KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
   09121 Transcription
 
   09122 Translation
 
   09123 Folding, sorting and degradation
     03060 Protein export [PATH:hsa03060]
     04141 Protein processing in endoplasmic reticulum [PATH:hsa04141]
     04130 SNARE interactions in vesicular transport [PATH:hsa04130]
     04120 Ubiquitin mediated proteolysis [PATH:hsa04120]
       10054 UBA2; ubiquitin like modifier activating enzyme 2
       10055 SAE1; SUMO1 activating enzyme subunit 1
       10075 HUWE1; HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
       10273 STUB1; STIP1 homology and U-box containing protein 1
       10277 UBE4B; ubiquitination factor E4B
       10393 ANAPC10; anaphase promoting complex subunit 10
       10401 PIAS3; protein inhibitor of activated STAT 3
       10477 UBE2E3; ubiquitin conjugating enzyme E2 E3
       11059 WWP1; WW domain containing E3 ubiquitin protein ligase 1
       11060 WWP2; WW domain containing E3 ubiquitin protein ligase 2
       11065 UBE2C; ubiquitin conjugating enzyme E2 C
       1161 ERCC8; ERCC excision repair 8, CSA ubiquitin ligase complex subunit
       118424 UBE2J2; ubiquitin conjugating enzyme E2 J2
       134111 UBE2QL1; ubiquitin conjugating enzyme E2 Q family like 1
       140739 UBE2F; ubiquitin conjugating enzyme E2 F (putative)
       148581 UBE2U; ubiquitin conjugating enzyme E2 U
       1642 DDB1; damage specific DNA binding protein 1
       1643 DDB2; damage specific DNA binding protein 2
       22888 UBOX5; U-box domain containing 5
       22954 TRIM32; tripartite motif containing 32
       23221 RHOBTB2; Rho related BTB domain containing 2
       23291 FBXW11; F-box and WD repeat domain containing 11
       23295 MGRN1; mahogunin ring finger 1
       23327 NEDD4L; NEDD4 like E3 ubiquitin protein ligase
       23624 CBLC; Cbl proto-oncogene C
       23759 PPIL2; peptidylprolyl isomerase like 2
       246184 CDC26; cell division cycle 26
       25847 ANAPC13; anaphase promoting complex subunit 13
       25898 RCHY1; ring finger and CHY zinc finger domain containing 1
       26091 HERC4; HECT and RLD domain containing E3 ubiquitin protein ligase 4
       26232 FBXO2; F-box protein 2
       26259 FBXW8; F-box and WD repeat domain containing 8
       26272 FBXO4; F-box protein 4
       27338 UBE2S; ubiquitin conjugating enzyme E2 S
       27339 PRPF19; pre-mRNA processing factor 19
       29882 ANAPC2; anaphase promoting complex subunit 2
       29945 ANAPC4; anaphase promoting complex subunit 4
       3093 UBE2K; ubiquitin conjugating enzyme E2 K
       326 AIRE; autoimmune regulator
       329 BIRC2; baculoviral IAP repeat containing 2
       330 BIRC3; baculoviral IAP repeat containing 3
       331 XIAP; X-linked inhibitor of apoptosis
       378884 NHLRC1; NHL repeat containing E3 ubiquitin protein ligase 1
       389898 UBE2NL; ubiquitin conjugating enzyme E2 N like (gene/pseudogene)
       4193 MDM2; MDM2 proto-oncogene
       4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1
       4281 MID1; midline 1
       4591 TRIM37; tripartite motif containing 37
       4734 NEDD4; NEDD4 E3 ubiquitin protein ligase
       5071 PRKN; parkin RBR E3 ubiquitin protein ligase
       51343 FZR1; fizzy and cell division cycle 20 related 1
       51366 UBR5; ubiquitin protein ligase E3 component n-recognin 5
       51433 ANAPC5; anaphase promoting complex subunit 5
       51434 ANAPC7; anaphase promoting complex subunit 7
       51465 UBE2J1; ubiquitin conjugating enzyme E2 J1
       51529 ANAPC11; anaphase promoting complex subunit 11
       51588 PIAS4; protein inhibitor of activated STAT 4
       51619 UBE2D4; ubiquitin conjugating enzyme E2 D4 (putative)
       5371 PML; PML nuclear body scaffold
       54926 UBE2R2; ubiquitin conjugating enzyme E2 R2
       55070 DET1; DET1 partner of COP1 E3 ubiquitin ligase
       55120 FANCL; FA complementation group L
       55236 UBA6; ubiquitin like modifier activating enzyme 6
       55284 UBE2W; ubiquitin conjugating enzyme E2 W
       55294 FBXW7; F-box and WD repeat domain containing 7
       55585 UBE2Q1; ubiquitin conjugating enzyme E2 Q1
       55958 KLHL9; kelch like family member 9
       57154 SMURF1; SMAD specific E3 ubiquitin protein ligase 1
       57448 BIRC6; baculoviral IAP repeat containing 6
       6233 RPS27A; ribosomal protein S27a
       63893 UBE2O; ubiquitin conjugating enzyme E2 O
       64326 COP1; COP1 E3 ubiquitin ligase
       64682 ANAPC1; anaphase promoting complex subunit 1
       64750 SMURF2; SMAD specific E3 ubiquitin protein ligase 2
       6477 SIAH1; siah E3 ubiquitin protein ligase 1
       6500 SKP1; S-phase kinase associated protein 1
       6502 SKP2; S-phase kinase associated protein 2
       65264 UBE2Z; ubiquitin conjugating enzyme E2 Z
       672 BRCA1; BRCA1 DNA repair associated
       6921 ELOC; elongin C
       6923 ELOB; elongin B
       7189 TRAF6; TNF receptor associated factor 6
       7311 UBA52; ubiquitin A-52 residue ribosomal protein fusion product 1
       7314 UBB; ubiquitin B
       7316 UBC; ubiquitin C
       7317 UBA1; ubiquitin like modifier activating enzyme 1
       7318 UBA7; ubiquitin like modifier activating enzyme 7
       7319 UBE2A; ubiquitin conjugating enzyme E2 A
       7320 UBE2B; ubiquitin conjugating enzyme E2 B
       7321 UBE2D1; ubiquitin conjugating enzyme E2 D1
       7322 UBE2D2; ubiquitin conjugating enzyme E2 D2
       7323 UBE2D3; ubiquitin conjugating enzyme E2 D3
       7324 UBE2E1; ubiquitin conjugating enzyme E2 E1
       7325 UBE2E2; ubiquitin conjugating enzyme E2 E2
       7326 UBE2G1; ubiquitin conjugating enzyme E2 G1
       7327 UBE2G2; ubiquitin conjugating enzyme E2 G2
       7328 UBE2H; ubiquitin conjugating enzyme E2 H
       7329 UBE2I; ubiquitin conjugating enzyme E2 I
       7332 UBE2L3; ubiquitin conjugating enzyme E2 L3
       7334 UBE2N; ubiquitin conjugating enzyme E2 N
       7337 UBE3A; ubiquitin protein ligase E3A
       7428 VHL; von Hippel-Lindau tumor suppressor
       79444 BIRC7; baculoviral IAP repeat containing 7
       8065 CUL5; cullin 5
       83737 ITCH; itchy E3 ubiquitin protein ligase
       84447 SYVN1; synoviolin 1
       8450 CUL4B; cullin 4B
       8451 CUL4A; cullin 4A
       8452 CUL3; cullin 3
       8453 CUL2; cullin 2
       8454 CUL1; cullin 1
       8554 PIAS1; protein inhibitor of activated STAT 1
       8651 SOCS1; suppressor of cytokine signaling 1
       867 CBL; Cbl proto-oncogene
       868 CBLB; Cbl proto-oncogene B
       8697 CDC23; cell division cycle 23
       8881 CDC16; cell division cycle 16
       8916 HERC3; HECT and RLD domain containing E3 ubiquitin protein ligase 3
       8924 HERC2; HECT and RLD domain containing E3 ubiquitin protein ligase 2
       8925 HERC1; HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
       8945 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
       89910 UBE3B; ubiquitin protein ligase E3B
       9021 SOCS3; suppressor of cytokine signaling 3
       90293 KLHL13; kelch like family member 13
       9039 UBA3; ubiquitin like modifier activating enzyme 3
       9040 UBE2M; ubiquitin conjugating enzyme E2 M
       9063 PIAS2; protein inhibitor of activated STAT 2
       9246 UBE2L6; ubiquitin conjugating enzyme E2 L6
       92912 UBE2Q2; ubiquitin conjugating enzyme E2 Q2
       9320 TRIP12; thyroid hormone receptor interactor 12
       9354 UBE4A; ubiquitination factor E4A
       9616 RNF7; ring finger protein 7
       9690 UBE3C; ubiquitin protein ligase E3C
       9817 KEAP1; kelch like ECH associated protein 1
       9820 CUL7; cullin 7
       9886 RHOBTB1; Rho related BTB domain containing 1
       991 CDC20; cell division cycle 20
       996 CDC27; cell division cycle 27
       997 CDC34; cell division cycle 34, ubiqiutin conjugating enzyme
       9978 RBX1; ring-box 1
K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
K03357 APC10; anaphase-promoting complex subunit 10
K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
K05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]
K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
K10570 ERCC8; DNA excision repair protein ERCC-8
K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
K10584 UBE2U; ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23]
K10610 DDB1; DNA damage-binding protein 1
K10140 DDB2; DNA damage-binding protein 2
K10600 UBOX5; U-box domain-containing protein 5
K10607 TRIM32; tripartite motif-containing protein 32 [EC:2.3.2.27]
K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]
K13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]
K22518 CBLC; E3 ubiquitin-protein ligase CBL-C [EC:2.3.2.27]
K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
K03359 APC12; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
K10099 FBXO2; F-box protein 2
K10264 FBXW8; F-box and WD-40 domain protein 8
K10291 FBXO4; F-box protein 4
K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
K03349 APC2; anaphase-promoting complex subunit 2
K03351 APC4; anaphase-promoting complex subunit 4
K04649 HIP2; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
K10603 AIRE; autoimmune regulator
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K08285 TRIM18; midline 1 [EC:2.3.2.27]
K10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]
K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
K04556 PARK2; parkin [EC:2.3.2.31]
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
K03352 APC5; anaphase-promoting complex subunit 5
K03354 APC7; anaphase-promoting complex subunit 7
K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
K03358 APC11; anaphase-promoting complex subunit 11
K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K10054 PML; probable transcription factor PML
K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
K10571 DET1; de-etiolated-1
K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
K10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]
K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.25]
K10260 FBXW7; F-box and WD-40 domain protein 7
K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
K10447 KLHL9_13; kelch-like protein 9/13
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K03348 APC1; anaphase-promoting complex subunit 1
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K03094 SKP1; S-phase kinase-associated protein 1
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
K10698 UBE1L; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]
K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K10612 CUL5; cullin 5
K05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
K10609 CUL4; cullin 4
K10609 CUL4; cullin 4
K03869 CUL3; cullin 3
K03870 CUL2; cullin 2
K03347 CUL1; cullin 1
K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
K04694 SOCS1; suppressor of cytokine signaling 1
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K03355 APC8; anaphase-promoting complex subunit 8
K03353 APC6; anaphase-promoting complex subunit 6
K10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]
K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
K10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
K04696 SOCS3; suppressor of cytokine signaling 3
K10447 KLHL9_13; kelch-like protein 9/13
K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
K04553 UBE2L6; ubiquitin-conjugating enzyme E2 L6 [EC:2.3.2.23]
K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
K10611 RBX2; RING-box protein 2
K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
K10456 KLHL19; kelch-like protein 19
K10613 CUL7; cullin 7
K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K03350 APC3; anaphase-promoting complex subunit 3
K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
     04122 Sulfur relay system [PATH:hsa04122]
     03050 Proteasome [PATH:hsa03050]
     03018 RNA degradation [PATH:hsa03018]
 
   09124 Replication and repair
     03030 DNA replication [PATH:hsa03030]
     03410 Base excision repair [PATH:hsa03410]
     03420 Nucleotide excision repair [PATH:hsa03420]
       100533467 BIVM-ERCC5; BIVM-ERCC5 readthrough
       1022 CDK7; cyclin dependent kinase 7
       1069 CETN2; centrin 2
       10714 POLD3; DNA polymerase delta 3, accessory subunit
       1161 ERCC8; ERCC excision repair 8, CSA ubiquitin ligase complex subunit
       1642 DDB1; damage specific DNA binding protein 1
       1643 DDB2; damage specific DNA binding protein 2
       2067 ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit
       2068 ERCC2; ERCC excision repair 2, TFIIH core complex helicase subunit
       2071 ERCC3; ERCC excision repair 3, TFIIH core complex helicase subunit
       2072 ERCC4; ERCC excision repair 4, endonuclease catalytic subunit
       2073 ERCC5; ERCC excision repair 5, endonuclease
       2074 ERCC6; ERCC excision repair 6, chromatin remodeling factor
       2965 GTF2H1; general transcription factor IIH subunit 1
       2966 GTF2H2; general transcription factor IIH subunit 2
       2967 GTF2H3; general transcription factor IIH subunit 3
       2968 GTF2H4; general transcription factor IIH subunit 4
       29935 RPA4; replication protein A4
       3978 LIG1; DNA ligase 1
       404672 GTF2H5; general transcription factor IIH subunit 5
       4331 MNAT1; MNAT1 component of CDK activating kinase
       5111 PCNA; proliferating cell nuclear antigen
       54107 POLE3; DNA polymerase epsilon 3, accessory subunit
       5424 POLD1; DNA polymerase delta 1, catalytic subunit
       5425 POLD2; DNA polymerase delta 2, accessory subunit
       5426 POLE; DNA polymerase epsilon, catalytic subunit
       5427 POLE2; DNA polymerase epsilon 2, accessory subunit
       56655 POLE4; DNA polymerase epsilon 4, accessory subunit
       57804 POLD4; DNA polymerase delta 4, accessory subunit
       5886 RAD23A; RAD23 homolog A, nucleotide excision repair protein
       5887 RAD23B; RAD23 homolog B, nucleotide excision repair protein
       5981 RFC1; replication factor C subunit 1
       5982 RFC2; replication factor C subunit 2
       5983 RFC3; replication factor C subunit 3
       5984 RFC4; replication factor C subunit 4
       5985 RFC5; replication factor C subunit 5
       6117 RPA1; replication protein A1
       6118 RPA2; replication protein A2
       6119 RPA3; replication protein A3
       728340 GTF2H2C; GTF2H2 family member C
       730394 GTF2H2C_2; GTF2H2 family member C, copy 2
       7507 XPA; XPA, DNA damage recognition and repair factor
       7508 XPC; XPC complex subunit, DNA damage recognition and repair factor
       8450 CUL4B; cullin 4B
       8451 CUL4A; cullin 4A
       902 CCNH; cyclin H
       9978 RBX1; ring-box 1
K10846 ERCC5; DNA excision repair protein ERCC-5
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K10840 CETN2; centrin-2
K03504 POLD3; DNA polymerase delta subunit 3
K10570 ERCC8; DNA excision repair protein ERCC-8
K10610 DDB1; DNA damage-binding protein 1
K10140 DDB2; DNA damage-binding protein 2
K10849 ERCC1; DNA excision repair protein ERCC-1
K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:3.6.4.12]
K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:3.6.4.12]
K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K10846 ERCC5; DNA excision repair protein ERCC-5
K10841 ERCC6; DNA excision repair protein ERCC-6
K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
K10741 RPA4; replication factor A4
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
K10842 MNAT1; CDK-activating kinase assembly factor MAT1
K04802 PCNA; proliferating cell nuclear antigen
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K03505 POLD4; DNA polymerase delta subunit 4
K10839 RAD23; UV excision repair protein RAD23
K10839 RAD23; UV excision repair protein RAD23
K10754 RFC1; replication factor C subunit 1
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K07466 RFA1; replication factor A1
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K10847 XPA; DNA-repair protein complementing XP-A cells
K10838 XPC; xeroderma pigmentosum group C-complementing protein
K10609 CUL4; cullin 4
K10609 CUL4; cullin 4
K06634 CCNH; cyclin H
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
     03430 Mismatch repair [PATH:hsa03430]
     03440 Homologous recombination [PATH:hsa03440]
     03450 Non-homologous end-joining [PATH:hsa03450]
     03460 Fanconi anemia pathway [PATH:hsa03460]
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09171 Infectious disease: bacterial
 
   09172 Infectious disease: viral
     05166 Human T-cell leukemia virus 1 infection [PATH:hsa05166]
     05170 Human immunodeficiency virus 1 infection [PATH:hsa05170]
       10000 AKT3; AKT serine/threonine kinase 3
       10053 AP1M2; adaptor related protein complex 1 subunit mu 2
       100913187 APOBEC3A_B; APOBEC3A and APOBEC3B deletion hybrid
       10298 PAK4; p21 (RAC1) activated kinase 4
       10454 TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1
       10681 GNB5; G protein subunit beta 5
       106821730 BUB1B-PAK6; BUB1B-PAK6 readthrough
       1072 CFL1; cofilin 1
       1073 CFL2; cofilin 2
       1111 CHEK1; checkpoint kinase 1
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       115004 CGAS; cyclic GMP-AMP synthase
       1174 AP1S1; adaptor related protein complex 1 subunit sigma 1
       1234 CCR5; C-C motif chemokine receptor 5
       130340 AP1S3; adaptor related protein complex 1 subunit sigma 3
       1398 CRK; CRK proto-oncogene, adaptor protein
       1399 CRKL; CRK like proto-oncogene, adaptor protein
       140564 APOBEC3D; apolipoprotein B mRNA editing enzyme catalytic subunit 3D
       1432 MAPK14; mitogen-activated protein kinase 14
       162 AP1B1; adaptor related protein complex 1 subunit beta 1
       163688 CALML6; calmodulin like 6
       164 AP1G1; adaptor related protein complex 1 subunit gamma 1
       1642 DDB1; damage specific DNA binding protein 1
       164668 APOBEC3H; apolipoprotein B mRNA editing enzyme catalytic subunit 3H
       200315 APOBEC3A; apolipoprotein B mRNA editing enzyme catalytic subunit 3A
       200316 APOBEC3F; apolipoprotein B mRNA editing enzyme catalytic subunit 3F
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       2185 PTK2B; protein tyrosine kinase 2 beta
       23118 TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2
       23291 FBXW11; F-box and WD repeat domain containing 11
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       2475 MTOR; mechanistic target of rapamycin kinase
       25939 SAMHD1; SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
       27350 APOBEC3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C
       2767 GNA11; G protein subunit alpha 11
       2770 GNAI1; G protein subunit alpha i1
       2771 GNAI2; G protein subunit alpha i2
       2773 GNAI3; G protein subunit alpha i3
       2775 GNAO1; G protein subunit alpha o1
       2776 GNAQ; G protein subunit alpha q
       2782 GNB1; G protein subunit beta 1
       2783 GNB2; G protein subunit beta 2
       2784 GNB3; G protein subunit beta 3
       2785 GNG3; G protein subunit gamma 3
       2786 GNG4; G protein subunit gamma 4
       2787 GNG5; G protein subunit gamma 5
       2788 GNG7; G protein subunit gamma 7
       2790 GNG10; G protein subunit gamma 10
       2791 GNG11; G protein subunit gamma 11
       2792 GNGT1; G protein subunit gamma transducin 1
       2793 GNGT2; G protein subunit gamma transducin 2
       29110 TBK1; TANK binding kinase 1
       2923 PDIA3; protein disulfide isomerase family A member 3
       3105 HLA-A; major histocompatibility complex, class I, A
       3106 HLA-B; major histocompatibility complex, class I, B
       3107 HLA-C; major histocompatibility complex, class I, C
       3133 HLA-E; major histocompatibility complex, class I, E
       3134 HLA-F; major histocompatibility complex, class I, F
       3135 HLA-G; major histocompatibility complex, class I, G
       3265 HRAS; HRas proto-oncogene, GTPase
       340061 STING1; stimulator of interferon response cGAMP interactor 1
       3439 IFNA1; interferon alpha 1
       3440 IFNA2; interferon alpha 2
       3441 IFNA4; interferon alpha 4
       3442 IFNA5; interferon alpha 5
       3443 IFNA6; interferon alpha 6
       3444 IFNA7; interferon alpha 7
       3445 IFNA8; interferon alpha 8
       3446 IFNA10; interferon alpha 10
       3447 IFNA13; interferon alpha 13
       3448 IFNA14; interferon alpha 14
       3449 IFNA16; interferon alpha 16
       3451 IFNA17; interferon alpha 17
       3452 IFNA21; interferon alpha 21
       3456 IFNB1; interferon beta 1
       355 FAS; Fas cell surface death receptor
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       356 FASLG; Fas ligand
       3654 IRAK1; interleukin 1 receptor associated kinase 1
       3661 IRF3; interferon regulatory factor 3
       3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
       3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
       3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       3845 KRAS; KRAS proto-oncogene, GTPase
       3984 LIMK1; LIM domain kinase 1
       3985 LIMK2; LIM domain kinase 2
       4615 MYD88; MYD88 innate immune signal transduction adaptor
       472 ATM; ATM serine/threonine kinase
       4772 NFATC1; nuclear factor of activated T cells 1
       4773 NFATC2; nuclear factor of activated T cells 2
       4775 NFATC3; nuclear factor of activated T cells 3
       4776 NFATC4; nuclear factor of activated T cells 4
       4790 NFKB1; nuclear factor kappa B subunit 1
       4792 NFKBIA; NFKB inhibitor alpha
       4893 NRAS; NRAS proto-oncogene, GTPase
       494551 WEE2; WEE2 oocyte meiosis inhibiting kinase
       5058 PAK1; p21 (RAC1) activated kinase 1
       5062 PAK2; p21 (RAC1) activated kinase 2
       5063 PAK3; p21 (RAC1) activated kinase 3
       51135 IRAK4; interleukin 1 receptor associated kinase 4
       51764 GNG13; G protein subunit gamma 13
       51806 CALML5; calmodulin like 5
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       5335 PLCG1; phospholipase C gamma 1
       5336 PLCG2; phospholipase C gamma 2
       54205 CYCS; cytochrome c, somatic
       54331 GNG2; G protein subunit gamma 2
       545 ATR; ATR serine/threonine kinase
       5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
       5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
       5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
       5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
       5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
       5578 PRKCA; protein kinase C alpha
       5579 PRKCB; protein kinase C beta
       5582 PRKCG; protein kinase C gamma
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       55970 GNG12; G protein subunit gamma 12
       5599 MAPK8; mitogen-activated protein kinase 8
       5600 MAPK11; mitogen-activated protein kinase 11
       5601 MAPK9; mitogen-activated protein kinase 9
       5602 MAPK10; mitogen-activated protein kinase 10
       5603 MAPK13; mitogen-activated protein kinase 13
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5606 MAP2K3; mitogen-activated protein kinase kinase 3
       5608 MAP2K6; mitogen-activated protein kinase kinase 6
       5609 MAP2K7; mitogen-activated protein kinase kinase 7
       567 B2M; beta-2-microglobulin
       56924 PAK6; p21 (RAC1) activated kinase 6
       57144 PAK5; p21 (RAC1) activated kinase 5
       572 BAD; BCL2 associated agonist of cell death
       5747 PTK2; protein tyrosine kinase 2
       578 BAK1; BCL2 antagonist/killer 1
       581 BAX; BCL2 associated X, apoptosis regulator
       5829 PXN; paxillin
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       59345 GNB4; G protein subunit beta 4
       596 BCL2; BCL2 apoptosis regulator
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       598 BCL2L1; BCL2 like 1
       60489 APOBEC3G; apolipoprotein B mRNA editing enzyme catalytic subunit 3G
       6198 RPS6KB1; ribosomal protein S6 kinase B1
       6199 RPS6KB2; ribosomal protein S6 kinase B2
       6300 MAPK12; mitogen-activated protein kinase 12
       637 BID; BH3 interacting domain death agonist
       6500 SKP1; S-phase kinase associated protein 1
       684 BST2; bone marrow stromal cell antigen 2
       6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
       6890 TAP1; transporter 1, ATP binding cassette subfamily B member
       6891 TAP2; transporter 2, ATP binding cassette subfamily B member
       6892 TAPBP; TAP binding protein
       6921 ELOC; elongin C
       6923 ELOB; elongin B
       7097 TLR2; toll like receptor 2
       7099 TLR4; toll like receptor 4
       7124 TNF; tumor necrosis factor
       7132 TNFRSF1A; TNF receptor superfamily member 1A
       7133 TNFRSF1B; TNF receptor superfamily member 1B
       7186 TRAF2; TNF receptor associated factor 2
       7188 TRAF5; TNF receptor associated factor 5
       7189 TRAF6; TNF receptor associated factor 6
       7465 WEE1; WEE1 G2 checkpoint kinase
       7852 CXCR4; C-X-C motif chemokine receptor 4
       801 CALM1; calmodulin 1
       805 CALM2; calmodulin 2
       8065 CUL5; cullin 5
       808 CALM3; calmodulin 3
       810 CALML3; calmodulin like 3
       811 CALR; calreticulin
       836 CASP3; caspase 3
       841 CASP8; caspase 8
       842 CASP9; caspase 9
       8450 CUL4B; cullin 4B
       8451 CUL4A; cullin 4A
       8454 CUL1; cullin 1
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       85363 TRIM5; tripartite motif containing 5
       85417 CCNB3; cyclin B3
       8717 TRADD; TNFRSF1A associated via death domain
       8737 RIPK1; receptor interacting serine/threonine kinase 1
       8772 FADD; Fas associated via death domain
       8905 AP1S2; adaptor related protein complex 1 subunit sigma 2
       8906 AP1G2; adaptor related protein complex 1 subunit gamma 2
       8907 AP1M1; adaptor related protein complex 1 subunit mu 1
       891 CCNB1; cyclin B1
       8945 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
       9133 CCNB2; cyclin B2
       915 CD3D; CD3d molecule
       916 CD3E; CD3e molecule
       917 CD3G; CD3g molecule
       91860 CALML4; calmodulin like 4
       919 CD247; CD247 molecule
       920 CD4; CD4 molecule
       94235 GNG8; G protein subunit gamma 8
       9582 APOBEC3B; apolipoprotein B mRNA editing enzyme catalytic subunit 3B
       9616 RNF7; ring finger protein 7
       9730 DCAF1; DDB1 and CUL4 associated factor 1
       983 CDK1; cyclin dependent kinase 1
       995 CDC25C; cell division cycle 25C
       9978 RBX1; ring-box 1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K12393 AP1M; AP-1 complex subunit mu
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05765 CFL; cofilin
K05765 CFL; cofilin
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K17834 MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
K04180 CCR5; C-C chemokine receptor type 5
K12395 AP1S3; AP-1 complex subunit sigma-3
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K12392 AP1B1; AP-1 complex subunit beta-1
K02183 CALM; calmodulin
K12391 AP1G1; AP-1 complex subunit gamma-1
K10610 DDB1; DNA damage-binding protein 1
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05871 PTK2B; focal adhesion kinase 2 [EC:2.7.10.2]
K04404 MAP3K7IP2; TAK1-binding protein 2
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K04379 FOS; proto-oncogene protein c-fos
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K02833 HRAS; GTPase HRas
K12654 TMEM173; transmembrane protein 173
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K05411 IRF3; interferon regulatory factor 3
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04448 JUN; transcription factor AP-1
K07827 KRAS; GTPase KRas
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K07828 NRAS; GTPase NRas
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K02183 CALM; calmodulin
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K08738 CYC; cytochrome c
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K08055 B2M; beta-2-microglobulin
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K14021 BAK; Bcl-2 homologous antagonist/killer
K02159 BAX; apoptosis regulator BAX
K05760 PXN; paxillin
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K02161 BCL2; apoptosis regulator Bcl-2
K04735 RELA; transcription factor p65
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04726 BID; BH3 interacting domain death agonist
K03094 SKP1; S-phase kinase-associated protein 1
K06731 BST2; bone marrow stromal cell antigen 2
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K05653 ABCB2; ATP-binding cassette, subfamily B (MDR/TAP), member 2
K05654 ABCB3; ATP-binding cassette, subfamily B (MDR/TAP), member 3
K08058 TAPBP; TAP binding protein (tapasin)
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K10159 TLR2; toll-like receptor 2
K10160 TLR4; toll-like receptor 4
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B; tumor necrosis factor receptor superfamily member 1B
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K04189 CXCR4; C-X-C chemokine receptor type 4
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K10612 CUL5; cullin 5
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K08057 CALR; calreticulin
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K10609 CUL4; cullin 4
K10609 CUL4; cullin 4
K03347 CUL1; cullin 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K02373 FADD; FAS-associated death domain protein
K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
K12391 AP1G1; AP-1 complex subunit gamma-1
K12393 AP1M; AP-1 complex subunit mu
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K02183 CALM; calmodulin
K06453 CD3Z; CD3Z antigen, zeta polypeptide
K06454 CD4; T-cell surface glycoprotein CD4
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
K10611 RBX2; RING-box protein 2
K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
     05161 Hepatitis B [PATH:hsa05161]
     05160 Hepatitis C [PATH:hsa05160]
     05171 Coronavirus disease - COVID-19 [PATH:hsa05171]
     05164 Influenza A [PATH:hsa05164]
     05162 Measles [PATH:hsa05162]
     05168 Herpes simplex virus 1 infection [PATH:hsa05168]
     05163 Human cytomegalovirus infection [PATH:hsa05163]
     05167 Kaposi sarcoma-associated herpesvirus infection [PATH:hsa05167]
     05169 Epstein-Barr virus infection [PATH:hsa05169]
     05165 Human papillomavirus infection [PATH:hsa05165]
 
   09174 Infectious disease: parasitic
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: January 16, 2021