KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
   09151 Immune system
 
   09152 Endocrine system
 
   09153 Circulatory system
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
     04320 Dorso-ventral axis formation
     04360 Axon guidance [PATH:hsa04360]
       22854 NTNG1; netrin G1
       84628 NTNG2; netrin G2
       57689 LRRC4C; leucine rich repeat containing 4C
       64101 LRRC4; leucine rich repeat containing 4
       9423 NTN1; netrin 1
       4917 NTN3; netrin 3
       59277 NTN4; netrin 4
       1630 DCC; DCC netrin 1 receptor
       5335 PLCG1; phospholipase C gamma 1
       5336 PLCG2; phospholipase C gamma 2
       7220 TRPC1; transient receptor potential cation channel subfamily C member 1
       7222 TRPC3; transient receptor potential cation channel subfamily C member 3
       7223 TRPC4; transient receptor potential cation channel subfamily C member 4
       7224 TRPC5; transient receptor potential cation channel subfamily C member 5
       7225 TRPC6; transient receptor potential cation channel subfamily C member 6
       5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
       5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
       5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
       5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
       5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
       4773 NFATC2; nuclear factor of activated T cells 2
       4775 NFATC3; nuclear factor of activated T cells 3
       4776 NFATC4; nuclear factor of activated T cells 4
       5747 PTK2; protein tyrosine kinase 2
       2534 FYN; FYN proto-oncogene, Src family tyrosine kinase
       6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       998 CDC42; cell division cycle 42
       3983 ABLIM1; actin binding LIM protein 1
       22885 ABLIM3; actin binding LIM protein family member 3
       84448 ABLIM2; actin binding LIM protein family member 2
       4690 NCK1; NCK adaptor protein 1
       5058 PAK1; p21 (RAC1) activated kinase 1
       5062 PAK2; p21 (RAC1) activated kinase 2
       5063 PAK3; p21 (RAC1) activated kinase 3
       10298 PAK4; p21 (RAC1) activated kinase 4
       57144 PAK5; p21 (RAC1) activated kinase 5
       56924 PAK6; p21 (RAC1) activated kinase 6
       106821730 BUB1B-PAK6; BUB1B-PAK6 readthrough
       387 RHOA; ras homolog family member A
       6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
       9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
       90249 UNC5A; unc-5 netrin receptor A
       219699 UNC5B; unc-5 netrin receptor B
       8633 UNC5C; unc-5 netrin receptor C
       137970 UNC5D; unc-5 netrin receptor D
       5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
       56963 RGMA; repulsive guidance molecule BMP co-receptor a
       4756 NEO1; neogenin 1
       4636 MYL5; myosin light chain 5
       10398 MYL9; myosin light chain 9
       103910 MYL12B; myosin light chain 12B
       10627 MYL12A; myosin light chain 12A
       23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
       9860 LRIG2; leucine rich repeats and immunoglobulin like domains 2
       1942 EFNA1; ephrin A1
       1943 EFNA2; ephrin A2
       1944 EFNA3; ephrin A3
       1945 EFNA4; ephrin A4
       1946 EFNA5; ephrin A5
       1947 EFNB1; ephrin B1
       1948 EFNB2; ephrin B2
       1949 EFNB3; ephrin B3
       2041 EPHA1; EPH receptor A1
       1969 EPHA2; EPH receptor A2
       2042 EPHA3; EPH receptor A3
       2043 EPHA4; EPH receptor A4
       2044 EPHA5; EPH receptor A5
       285220 EPHA6; EPH receptor A6
       2045 EPHA7; EPH receptor A7
       2046 EPHA8; EPH receptor A8
       2047 EPHB1; EPH receptor B1
       2048 EPHB2; EPH receptor B2
       2049 EPHB3; EPH receptor B3
       2050 EPHB4; EPH receptor B4
       2051 EPHB6; EPH receptor B6
       25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       55740 ENAH; ENAH actin regulator
       5921 RASA1; RAS p21 protein activator 1
       25791 NGEF; neuronal guanine nucleotide exchange factor
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       8440 NCK2; NCK adaptor protein 2
       5998 RGS3; regulator of G protein signaling 3
       6387 CXCL12; C-X-C motif chemokine ligand 12
       7852 CXCR4; C-X-C motif chemokine receptor 4
       2770 GNAI1; G protein subunit alpha i1
       2773 GNAI3; G protein subunit alpha i3
       2771 GNAI2; G protein subunit alpha i2
       6585 SLIT1; slit guidance ligand 1
       9353 SLIT2; slit guidance ligand 2
       6586 SLIT3; slit guidance ligand 3
       6091 ROBO1; roundabout guidance receptor 1
       6092 ROBO2; roundabout guidance receptor 2
       64221 ROBO3; roundabout guidance receptor 3
       23380 SRGAP2; SLIT-ROBO Rho GTPase activating protein 2
       57522 SRGAP1; SLIT-ROBO Rho GTPase activating protein 1
       9901 SRGAP3; SLIT-ROBO Rho GTPase activating protein 3
       10371 SEMA3A; semaphorin 3A
       7869 SEMA3B; semaphorin 3B
       10512 SEMA3C; semaphorin 3C
       223117 SEMA3D; semaphorin 3D
       9723 SEMA3E; semaphorin 3E
       6405 SEMA3F; semaphorin 3F
       56920 SEMA3G; semaphorin 3G
       5362 PLXNA2; plexin A2
       55558 PLXNA3; plexin A3
       5361 PLXNA1; plexin A1
       91584 PLXNA4; plexin A4
       8829 NRP1; neuropilin 1
       3897 L1CAM; L1 cell adhesion molecule
       3984 LIMK1; LIM domain kinase 1
       3985 LIMK2; LIM domain kinase 2
       1072 CFL1; cofilin 1
       1073 CFL2; cofilin 2
       29984 RHOD; ras homolog family member D
       27289 RND1; Rho family GTPase 1
       2242 FES; FES proto-oncogene, tyrosine kinase
       56896 DPYSL5; dihydropyrimidinase like 5
       1808 DPYSL2; dihydropyrimidinase like 2
       1020 CDK5; cyclin dependent kinase 5
       2932 GSK3B; glycogen synthase kinase 3 beta
       10505 SEMA4F; ssemaphorin 4F
       10507 SEMA4D; semaphorin 4D
       10509 SEMA4B; semaphorin 4B
       54910 SEMA4C; semaphorin 4C
       57715 SEMA4G; semaphorin 4G
       64218 SEMA4A; semaphorin 4A
       9037 SEMA5A; semaphorin 5A
       54437 SEMA5B; semaphorin 5B
       57556 SEMA6A; semaphorin 6A
       10501 SEMA6B; semaphorin 6B
       10500 SEMA6C; semaphorin 6C
       80031 SEMA6D; semaphorin 6D
       5364 PLXNB1; plexin B1
       23654 PLXNB2; plexin B2
       5365 PLXNB3; plexin B3
       4233 MET; MET proto-oncogene, receptor tyrosine kinase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       6237 RRAS; RAS related
       8482 SEMA7A; semaphorin 7A (JohnMiltonHagen blood group)
       10154 PLXNC1; plexin C1
       3688 ITGB1; integrin subunit beta 1
       6469 SHH; sonic hedgehog signaling molecule
       5727 PTCH1; patched 1
       6608 SMO; smoothened, frizzled class receptor
       5578 PRKCA; protein kinase C alpha
       3611 ILK; integrin linked kinase
       91653 BOC; BOC cell adhesion associated, oncogene regulated
       7474 WNT5A; Wnt family member 5A
       81029 WNT5B; Wnt family member 5B
       7976 FZD3; frizzled class receptor 3
       6259 RYK; receptor like tyrosine kinase
       815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
       816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       54361 WNT4; Wnt family member 4
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
       56288 PARD3; par-3 family cell polarity regulator
       5590 PRKCZ; protein kinase C zeta
       50855 PARD6A; par-6 family cell polarity regulator alpha
       84552 PARD6G; par-6 family cell polarity regulator gamma
       84612 PARD6B; par-6 family cell polarity regulator beta
       54434 SSH1; slingshot protein phosphatase 1
       54961 SSH3; slingshot protein phosphatase 3
       85464 SSH2; slingshot protein phosphatase 2
       655 BMP7; bone morphogenetic protein 7
       151449 GDF7; growth differentiation factor 7
       659 BMPR2; bone morphogenetic protein receptor type 2
       658 BMPR1B; bone morphogenetic protein receptor type 1B
K07522 NTNG1; netrin-G1
K16359 NTNG2; netrin-G2
K07523 LRRC4C; netrin-G1 ligand
K16351 LRRC4; netrin-G2 ligand
K06843 NTN1; netrin 1
K06844 NTN3; netrin 3
K06845 NTN4; netrin 4
K06765 DCC; deleted in colorectal carcinoma
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04964 TRPC1; transient receptor potential cation channel subfamily C member 1
K04966 TRPC3; transient receptor potential cation channel subfamily C member 3
K04967 TRPC4; transient receptor potential cation channel subfamily C member 4
K04968 TRPC5; transient receptor potential cation channel subfamily C member 5
K04969 TRPC6; transient receptor potential cation channel subfamily C member 6
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K07520 ABLIM; actin-binding LIM protein
K07520 ABLIM; actin-binding LIM protein
K07520 ABLIM; actin-binding LIM protein
K07365 NCK1; NCK adaptor protein 1
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K07521 UNC5; netrin receptor unc-5
K07521 UNC5; netrin receptor unc-5
K07521 UNC5; netrin receptor unc-5
K07521 UNC5; netrin receptor unc-5
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K23096 RGMA; repulsive guidance molecule A
K06766 NEO1; neogenin
K12753 MYL5; myosin regulatory light chain 5
K12755 MYL9; myosin regulatory light chain 9
K12757 MYL12; myosin regulatory light chain 12
K12757 MYL12; myosin regulatory light chain 12
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K24609 LRIG2; leucine-rich repeats and immunoglobulin-like domains protein 2
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05463 EFNB; ephrin-B
K05463 EFNB; ephrin-B
K05463 EFNB; ephrin-B
K05102 EPHA1; Eph receptor A1 [EC:2.7.10.1]
K05103 EPHA2; Eph receptor A2 [EC:2.7.10.1]
K05104 EPHA3; Eph receptor A3 [EC:2.7.10.1]
K05105 EPHA4; Eph receptor A4 [EC:2.7.10.1]
K05106 EPHA5; Eph receptor A5 [EC:2.7.10.1]
K05107 EPHA6; Eph receptor A6 [EC:2.7.10.1]
K05108 EPHA7; EphA7 [EC:2.7.10.1]
K05109 EPHA8; Eph receptor A8 [EC:2.7.10.1]
K05110 EPHB1; Eph receptor B1 [EC:2.7.10.1]
K05111 EPHB2; Eph receptor B2 [EC:2.7.10.1]
K05112 EPHB3; Eph receptor B3 [EC:2.7.10.1]
K05113 EPHB4; Eph receptor B4 [EC:2.7.10.1]
K05114 EPHB6; Eph receptor B6 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K05746 ENAH; enabled
K04352 RASA1; Ras GTPase-activating protein 1
K07525 NGEF; neuronal guanine nucleotide exchange factor
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K19862 NCK2; NCK adaptor protein 2
K07524 RGS3; regulator of G-protein signalling 3
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K06838 SLIT1; slit 1
K06839 SLIT2; slit 2
K06850 SLIT3; slit 3
K06753 ROBO1; roundabout, axon guidance receptor 1
K06754 ROBO2; roundabout, axon guidance receptor 2
K06755 ROBO3; roundabout, axon guidance receptor 3
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein
K06840 SEMA3; semaphorin 3
K06840 SEMA3; semaphorin 3
K06840 SEMA3; semaphorin 3
K06840 SEMA3; semaphorin 3
K06840 SEMA3; semaphorin 3
K06840 SEMA3; semaphorin 3
K06840 SEMA3; semaphorin 3
K06820 PLXNA; plexin A
K06820 PLXNA; plexin A
K06820 PLXNA; plexin A
K06820 PLXNA; plexin A
K06724 NRP1; neuropilin 1
K06550 L1CAM; L1 cell adhesion molecule
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05765 CFL; cofilin
K05765 CFL; cofilin
K07530 RHOD; Ras homolog gene family, member D
K07531 RND1; Rho family GTPase 1
K07527 FES; tyrosine-protein kinase Fes/Fps [EC:2.7.10.2]
K07529 DPYSL5; dihydropyrimidinase-like 5
K07528 DPYSL2; dihydropyrimidinase-like 2
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06521 SEMA4; semaphorin 4
K06521 SEMA4; semaphorin 4
K06521 SEMA4; semaphorin 4
K06521 SEMA4; semaphorin 4
K06521 SEMA4; semaphorin 4
K06521 SEMA4; semaphorin 4
K06841 SEMA5; semaphorin 5
K06841 SEMA5; semaphorin 5
K06842 SEMA6; semaphorin 6
K06842 SEMA6; semaphorin 6
K06842 SEMA6; semaphorin 6
K06842 SEMA6; semaphorin 6
K06821 PLXNB; plexin B
K06821 PLXNB; plexin B
K06821 PLXNB; plexin B
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07829 RRAS; Ras-related protein R-Ras
K06529 SEMA7; semaphorin 7
K06572 PLXNC; plexin C
K05719 ITGB1; integrin beta 1
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K20020 BOC; brother of CDO
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K02329 FZD3; frizzled 3
K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04237 PARD3; partitioning defective protein 3
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K16621 BMP7; bone morphogenetic protein 7
K20013 GDF7; growth differentiation factor 7
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
     04361 Axon regeneration
     04380 Osteoclast differentiation [PATH:hsa04380]
 
   09149 Aging
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 18, 2024