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1. Oxidoreductases
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2. Transferases
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3. Hydrolases
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3.1 Acting on ester bonds
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3.2 Glycosylases
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3.3 Acting on ether bonds
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3.4 Acting on peptide bonds (peptidases)
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3.4.11 Aminopeptidases
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3.4.13 Dipeptidases
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3.4.14 Dipeptidyl-peptidases and tripeptidyl-peptidases
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3.4.15 Peptidyl-dipeptidases
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3.4.16 Serine-type carboxypeptidases
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3.4.17 Metallocarboxypeptidases
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3.4.18 Cysteine-type carboxypeptidases
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3.4.19 Omega peptidases
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3.4.21 Serine endopeptidases
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3.4.22 Cysteine endopeptidases
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3.4.23 Aspartic endopeptidases
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3.4.24 Metalloendopeptidases
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3.4.24.1 atrolysin A
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3.4.24.3 microbial collagenase
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3.4.24.6 leucolysin
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3.4.24.7 interstitial collagenase
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3.4.24.11 neprilysin
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3.4.24.12 envelysin
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3.4.24.13 IgA-specific metalloendopeptidase
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3.4.24.14 procollagen N-endopeptidase
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3.4.24.15 thimet oligopeptidase
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3.4.24.16 neurolysin
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3.4.24.17 stromelysin 1
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3.4.24.18 meprin A
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3.4.24.19 procollagen C-endopeptidase
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3.4.24.20 peptidyl-Lys metalloendopeptidase
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3.4.24.21 astacin
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3.4.24.22 stromelysin 2
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3.4.24.23 matrilysin
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3.4.24.24 gelatinase A
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3.4.24.25 vibriolysin
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3.4.24.26 pseudolysin
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3.4.24.27 thermolysin
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3.4.24.28 bacillolysin
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3.4.24.29 aureolysin
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3.4.24.30 coccolysin
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3.4.24.31 mycolysin
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3.4.24.32 beta-lytic metalloendopeptidase
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3.4.24.33 peptidyl-Asp metalloendopeptidase
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3.4.24.34 neutrophil collagenase
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3.4.24.35 gelatinase B
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3.4.24.36 leishmanolysin
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3.4.24.37 saccharolysin
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3.4.24.38 gametolysin
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3.4.24.39 deuterolysin
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3.4.24.40 serralysin
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3.4.24.41 atrolysin B
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3.4.24.42 atrolysin C
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3.4.24.43 atroxase
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3.4.24.44 atrolysin E
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3.4.24.45 atrolysin F
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3.4.24.46 adamalysin
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3.4.24.47 horrilysin
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3.4.24.48 ruberlysin
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3.4.24.49 bothropasin
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3.4.24.50 bothrolysin
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3.4.24.51 ophiolysin
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3.4.24.52 trimerelysin I
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3.4.24.53 trimerelysin II
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3.4.24.54 mucrolysin
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3.4.24.55 pitrilysin
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3.4.24.56 insulysin
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3.4.24.57 O-sialoglycoprotein endopeptidase
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3.4.24.58 russellysin
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3.4.24.59 mitochondrial intermediate peptidase
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3.4.24.60 dactylysin
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3.4.24.61 nardilysin
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3.4.24.62 magnolysin
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3.4.24.63 meprin B
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3.4.24.64 mitochondrial processing peptidase
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3.4.24.65 macrophage elastase
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3.4.24.66 choriolysin L
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3.4.24.67 choriolysin H
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3.4.24.68 tentoxilysin
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3.4.24.69 bontoxilysin
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3.4.24.70 oligopeptidase A
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3.4.24.71 endothelin-converting enzyme 1
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3.4.24.72 fibrolase
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3.4.24.73 jararhagin
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3.4.24.74 fragilysin
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3.4.24.75 lysostaphin
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3.4.24.76 flavastacin
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3.4.24.77 snapalysin
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3.4.24.78 gpr endopeptidase
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3.4.24.79 pappalysin-1
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3.4.24.80 membrane-type matrix metalloproteinase-1
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3.4.24.81 ADAM10 endopeptidase
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3.4.24.82 ADAMTS-4 endopeptidase
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3.4.24.83 anthrax lethal factor endopeptidase
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3.4.24.84 Ste24 endopeptidase
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3.4.24.85 S2P endopeptidase
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3.4.24.86 ADAM 17 endopeptidase
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3.4.24.87 ADAMTS13 endopeptidase
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3.4.24.89 Pro-Pro endopeptidase
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3.4.24.-
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101 ADAM8; ADAM metallopeptidase domain 8
3792 KEL; Kell metallo-endopeptidase (Kell blood group)
2515 ADAM2; ADAM metallopeptidase domain 2
8754 ADAM9; ADAM metallopeptidase domain 9
8038 ADAM12; ADAM metallopeptidase domain 12
8751 ADAM15; ADAM metallopeptidase domain 15
8745 ADAM23; ADAM metallopeptidase domain 23
10531 PITRM1; pitrilysin metallopeptidase 1
4320 MMP11; matrix metallopeptidase 11
4322 MMP13; matrix metallopeptidase 13
4324 MMP15; matrix metallopeptidase 15
4325 MMP16; matrix metallopeptidase 16
4326 MMP17; matrix metallopeptidase 17
4327 MMP19; matrix metallopeptidase 19
9313 MMP20; matrix metallopeptidase 20
118856 MMP21; matrix metallopeptidase 21
8510 MMP23B; matrix metallopeptidase 23B
10893 MMP24; matrix metallopeptidase 24
64386 MMP25; matrix metallopeptidase 25
56547 MMP26; matrix metallopeptidase 26
64066 MMP27; matrix metallopeptidase 27
79148 MMP28; matrix metallopeptidase 28
8728 ADAM19; ADAM metallopeptidase domain 19
8748 ADAM20; ADAM metallopeptidase domain 20
8747 ADAM21; ADAM metallopeptidase domain 21
10863 ADAM28; ADAM metallopeptidase domain 28
11085 ADAM30; ADAM metallopeptidase domain 30
80332 ADAM33; ADAM metallopeptidase domain 33
9510 ADAMTS1; ADAM metallopeptidase with thrombospondin type 1 motif 1
9508 ADAMTS3; ADAM metallopeptidase with thrombospondin type 1 motif 3
11096 ADAMTS5; ADAM metallopeptidase with thrombospondin type 1 motif 5
11174 ADAMTS6; ADAM metallopeptidase with thrombospondin type 1 motif 6
11173 ADAMTS7; ADAM metallopeptidase with thrombospondin type 1 motif 7
11095 ADAMTS8; ADAM metallopeptidase with thrombospondin type 1 motif 8
56999 ADAMTS9; ADAM metallopeptidase with thrombospondin type 1 motif 9
81794 ADAMTS10; ADAM metallopeptidase with thrombospondin type 1 motif 10
81792 ADAMTS12; ADAM metallopeptidase with thrombospondin type 1 motif 12
140766 ADAMTS14; ADAM metallopeptidase with thrombospondin type 1 motif 14
170689 ADAMTS15; ADAM metallopeptidase with thrombospondin type 1 motif 15
170690 ADAMTS16; ADAM metallopeptidase with thrombospondin type 1 motif 16
170691 ADAMTS17; ADAM metallopeptidase with thrombospondin type 1 motif 17
170692 ADAMTS18; ADAM metallopeptidase with thrombospondin type 1 motif 18
171019 ADAMTS19; ADAM metallopeptidase with thrombospondin type 1 motif 19
27299 ADAMDEC1; ADAM like decysin 1
5251 PHEX; phosphate regulating endopeptidase homolog X-linked
60676 PAPPA2; pappalysin 2
10730 YME1L1; YME1 like 1 ATPase
10939 AFG3L2; AFG3 like matrix AAA peptidase subunit 2
6687 SPG7; SPG7 matrix AAA peptidase subunit, paraplegin
7092 TLL1; tolloid like 1
80070 ADAMTS20; ADAM metallopeptidase with thrombospondin type 1 motif 20
9427 ECEL1; endothelin converting enzyme like 1
7093 TLL2; tolloid like 2
89782 LMLN; leishmanolysin like peptidase
4185 ADAM11; ADAM metallopeptidase domain 11
53616 ADAM22; ADAM metallopeptidase domain 22
11086 ADAM29; ADAM metallopeptidase domain 29
203102 ADAM32; ADAM metallopeptidase domain 32
8756 ADAM7; ADAM metallopeptidase domain 7
8749 ADAM18; ADAM metallopeptidase domain 18
91419 ATP23; ATP23 metallopeptidase and ATP synthase assembly factor homolog
115209 OMA1; OMA1 zinc metallopeptidase
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K06540 ADAM8; disintegrin and metalloproteinase domain-containing protein 8 [EC:3.4.24.-]
K06577 KEL; Kell blood group glycoprotein [EC:3.4.24.-]
K06833 ADAM2; disintegrin and metalloproteinase domain-containing protein 2 [EC:3.4.24.-]
K06834 ADAM9; disintegrin and metalloproteinase domain-containing protein 9 [EC:3.4.24.-]
K06835 ADAM12; disintegrin and metalloproteinase domain-containing protein 12 [EC:3.4.24.-]
K06836 ADAM15; disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-]
K06837 ADAM23; disintegrin and metalloproteinase domain-containing protein 23 [EC:3.4.24.-]
K06972 PITRM1; presequence protease [EC:3.4.24.-]
K07993 MMP11; matrix metalloproteinase-11 (stromelysin 3) [EC:3.4.24.-]
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
K07995 MMP15; matrix metalloproteinase-15 (membrane-inserted) [EC:3.4.24.-]
K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
K07997 MMP17; matrix metalloproteinase-17 (membrane-inserted) [EC:3.4.24.-]
K07998 MMP19; matrix metalloproteinase-19 (RASI) [EC:3.4.24.-]
K07999 MMP20; matrix metalloproteinase-20 (enamelysin) [EC:3.4.24.-]
K08000 MMP21; matrix metalloproteinase-21 [EC:3.4.24.-]
K08001 MMP23; matrix metalloproteinase-23 (CA-MMP) [EC:3.4.24.-]
K08002 MMP24; matrix metalloproteinase-24 (membrane-inserted) [EC:3.4.24.-]
K08003 MMP25; matrix metalloproteinase-25 (membrane-inserted) [EC:3.4.24.-]
K08004 MMP26; matrix metalloproteinase-26 (matrilysin-2, endometase) [EC:3.4.24.-]
K08005 MMP27; matrix metalloproteinase-27 [EC:3.4.24.-]
K08006 MMP28; matrix metalloproteinase-28 (epilysin) [EC:3.4.24.-]
K08608 ADAM19; disintegrin and metalloproteinase domain-containing protein 19 [EC:3.4.24.-]
K08609 ADAM20; disintegrin and metalloproteinase domain-containing protein 20 [EC:3.4.24.-]
K08610 ADAM21; disintegrin and metalloproteinase domain-containing protein 21 [EC:3.4.24.-]
K08614 ADAM28; disintegrin and metalloproteinase domain-containing protein 28 [EC:3.4.24.-]
K08615 ADAM30; disintegrin and metalloproteinase domain-containing protein 30 [EC:3.4.24.-]
K08616 ADAM33; disintegrin and metalloproteinase domain-containing protein 33 [EC:3.4.24.-]
K08617 ADAMTS1; a disintegrin and metalloproteinase with thrombospondin motifs 1 [EC:3.4.24.-]
K08619 ADAMTS3; a disintegrin and metalloproteinase with thrombospondin motifs 3 [EC:3.4.24.-]
K08620 ADAMTS5; a disintegrin and metalloproteinase with thrombospondin motifs 5 [EC:3.4.24.-]
K08621 ADAMTS6; a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-]
K08622 ADAMTS7; a disintegrin and metalloproteinase with thrombospondin motifs 7 [EC:3.4.24.-]
K08623 ADAMTS8; a disintegrin and metalloproteinase with thrombospondin motifs 8 [EC:3.4.24.-]
K08624 ADAMTS9; a disintegrin and metalloproteinase with thrombospondin motifs 9 [EC:3.4.24.-]
K08625 ADAMTS10; a disintegrin and metalloproteinase with thrombospondin motifs 10 [EC:3.4.24.-]
K08626 ADAMTS12; a disintegrin and metalloproteinase with thrombospondin motifs 12 [EC:3.4.24.-]
K08628 ADAMTS14; a disintegrin and metalloproteinase with thrombospondin motifs 14 [EC:3.4.24.-]
K08629 ADAMTS15; a disintegrin and metalloproteinase with thrombospondin motifs 15 [EC:3.4.24.-]
K08630 ADAMTS16; a disintegrin and metalloproteinase with thrombospondin motifs 16 [EC:3.4.24.-]
K08631 ADAMTS17; a disintegrin and metalloproteinase with thrombospondin motifs 17 [EC:3.4.24.-]
K08632 ADAMTS18; a disintegrin and metalloproteinase with thrombospondin motifs 18 [EC:3.4.24.-]
K08633 ADAMTS19; a disintegrin and metalloproteinase with thrombospondin motifs 19 [EC:3.4.24.-]
K08634 ADAMDEC1; ADAM-like, decysin 1 [EC:3.4.24.-]
K08636 PHEX; phosphate-regulating neutral endopeptidase [EC:3.4.24.-]
K08647 PAPPA2; pappalysin-2 [EC:3.4.24.-]
K08955 YME1; ATP-dependent metalloprotease [EC:3.4.24.-]
K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
K09552 SPG7; spastic paraplegia 7 [EC:3.4.24.-]
K09608 TLL1; tolloid-like protein 1 [EC:3.4.24.-]
K09609 ADAMTS20; a disintegrin and metalloproteinase with thrombospondin motifs 20 [EC:3.4.24.-]
K09610 ECEL1; endothelin-converting enzyme-like 1 [EC:3.4.24.-]
K13047 TLL2; tolloid-like protein 2 [EC:3.4.24.-]
K13539 LMLN; leishmanolysin-like peptidase [EC:3.4.24.-]
K16067 ADAM11; disintegrin and metalloproteinase domain-containing protein 11 [EC:3.4.24.-]
K16068 ADAM22; disintegrin and metalloproteinase domain-containing protein 22 [EC:3.4.24.-]
K16069 ADAM29; disintegrin and metalloproteinase domain-containing protein 29 [EC:3.4.24.-]
K16070 ADAM32; disintegrin and metalloproteinase domain-containing protein 32 [EC:3.4.24.-]
K16071 ADAM7; disintegrin and metalloproteinase domain-containing protein 7 [EC:3.4.24.-]
K16909 ADAM18; disintegrin and metalloproteinase domain-containing protein 18 [EC:3.4.24.-]
K18156 ATP23; mitochondrial inner membrane protease ATP23 [EC:3.4.24.-]
K23010 OMA1; metalloendopeptidase OMA1, mitochondrial [EC:3.4.24.-]
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3.4.25 Threonine endopeptidases
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3.4.- Acting on peptide bonds (peptidases)
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3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
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3.6 Acting on acid anhydrides
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3.7 Acting on carbon-carbon bonds
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3.8 Acting on halide bonds
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3.9 Acting on phosphorus-nitrogen bonds
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3.10 Acting on sulfur-nitrogen bonds
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3.11 Acting on carbon-phosphorus bonds
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3.12 Acting on sulfur-sulfur bonds
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3.13 Acting on carbon-sulfur bonds
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3.-
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4. Lyases
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5. Isomerases
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6. Ligases
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7. Translocases
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