Ribosome Biogenesis - Homo sapiens (human)

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     KO
 Eukaryotic type
   Sno RNPs
   90S particles
   Pre-40S particles
     Kinases
     Export and cytoplasmic maturation factors
       27292 DIMT1; DIMT1 rRNA methyltransferase and ribosome maturation factor
       114049 BUD23; BUD23 rRNA methyltransferase and ribosome maturation factor
       29081 METTL5; methyltransferase like 5
       705 BYSL; bystin like
       84946 LTV1; LTV1 ribosome biogenesis factor
       28987 NOB1; NIN1 (RPN12) binding protein 1 homolog
       56902 PNO1; partner of NOB1 homolog
       5901 RAN; RAN, member RAS oncogene family
       102157402 AK6; adenylate kinase 6
       55720 TSR1; TSR1 ribosome maturation factor
       90121 TSR2; TSR2 ribosome maturation factor
       115939 TSR3; TSR3 ribosome maturation factor
       84306 PDCD2L; programmed cell death 2 like
       5134 PDCD2; programmed cell death 2
       7514 XPO1; exportin 1
       3837 KPNB1; karyopherin subunit beta 1
       3842 TNPO1; transportin 1
       79711 IPO4; importin 4
       3843 IPO5; importin 5
       10527 IPO7; importin 7
       55705 IPO9; importin 9
K14191 DIM1; 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase [EC:2.1.1.183] 
K19306 BUD23; 18S rRNA (guanine1575-N7)-methyltransferase [EC:2.1.1.309] 
K24418 METTL5; rRNA N6-adenosine-methyltransferase METTL5 
K14797 ENP1; essential nuclear protein 1 
K14798 LTV1; protein LTV1 
K11883 NOB1; RNA-binding protein NOB1 
K11884 PNO1; RNA-binding protein PNO1 
K07936 RAN; GTP-binding nuclear protein Ran 
K18532 AK6; adenylate kinase [EC:2.7.4.3] 
K14799 TSR1; pre-rRNA-processing protein TSR1 
K14800 TSR2; pre-rRNA-processing protein TSR2 
K09140 TSR3; pre-rRNA-processing protein TSR3 
K14801 TSR4; pre-rRNA-processing protein TSR4 
K14801 TSR4; pre-rRNA-processing protein TSR4 
K14290 XPO1; exportin-1 
K14293 KPNB1; importin subunit beta-1 
K18752 TNPO1; transportin-1 
K20221 IPO4; importin-4 
K20222 IPO5; importin-5 
K20223 IPO7; importin-7 
K20224 IPO9; importin-9 
     Other pre-40S particles
   Pre-60S particles
     Helicases
     GTPases
     RNases
     Kinases
     Export and cytoplasmic maturation factors
       10061 ABCF2; ATP binding cassette subfamily F member 2
       134218 DNAJC21; DnaJ heat shock protein family (Hsp40) member C21
       3692 EIF6; eukaryotic translation initiation factor 6
       3312 HSPA8; heat shock protein family A (Hsp70) member 8
       3303 HSPA1A; heat shock protein family A (Hsp70) member 1A
       3306 HSPA2; heat shock protein family A (Hsp70) member 2
       3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like
       3304 HSPA1B; heat shock protein family A (Hsp70) member 1B
       3310 HSPA6; heat shock protein family A (Hsp70) member 6
       51154 MRTO4; MRT4 homolog, ribosome maturation factor
       51068 NMD3; NMD3 ribosome export adaptor
       10482 NXF1; nuclear RNA export factor 1
       56001 NXF2; nuclear RNA export factor 2
       728343 NXF2B; nuclear RNA export factor 2B
       55998 NXF5; nuclear RNA export factor 5
       56000 NXF3; nuclear RNA export factor 3
       29107 NXT1; nuclear transport factor 2 like export factor 1
       55916 NXT2; nuclear transport factor 2 like export factor 2
       5901 RAN; RAN, member RAS oncogene family
       90441 ZNF622; zinc finger protein 622
       51119 SBDS; SBDS ribosome maturation factor
       166378 SPATA5; spermatogenesis associated 5
       14 AAMP; angio associated migratory cell protein
       7514 XPO1; exportin 1
       3837 KPNB1; karyopherin subunit beta 1
       3842 TNPO1; transportin 1
       79711 IPO4; importin 4
       3843 IPO5; importin 5
       10527 IPO7; importin 7
       55705 IPO9; importin 9
       11266 DUSP12; dual specificity phosphatase 12
K06185 ABCF2; ATP-binding cassette, subfamily F, member 2 
K09506 DNAJA5; DnaJ homolog subfamily A member 5 
K03264 EIF6; translation initiation factor 6 
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8 
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8 
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8 
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8 
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8 
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8 
K14815 MRT4; mRNA turnover protein 4 
K07562 NMD3; nonsense-mediated mRNA decay protein 3 
K14284 NXF; nuclear RNA export factor 
K14284 NXF; nuclear RNA export factor 
K14284 NXF; nuclear RNA export factor 
K14284 NXF; nuclear RNA export factor 
K14284 NXF; nuclear RNA export factor 
K14285 NXT1_2; NTF2-related export protein 1/2 
K14285 NXT1_2; NTF2-related export protein 1/2 
K07936 RAN; GTP-binding nuclear protein Ran 
K14816 REI1; pre-60S factor REI1 
K14574 SDO1; ribosome maturation protein SDO1 
K14575 AFG2; AAA family ATPase 
K14818 SQT1; ribosome assembly protein SQT1 
K14290 XPO1; exportin-1 
K14293 KPNB1; importin subunit beta-1 
K18752 TNPO1; transportin-1 
K20221 IPO4; importin-4 
K20222 IPO5; importin-5 
K20223 IPO7; importin-7 
K20224 IPO9; importin-9 
K14819 DUSP12; dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48] 
     5-FMC complex
     Other pre-60S particles
   Other ribosome biogenesis factors
 
 Prokaryotic type
 
 Related small nucleolar RNAs

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Last updated: October 8, 2020