Messenger RNA Biogenesis - Homo sapiens (human)

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     KO
 Eukaryotic type
   mRNA processing factors
   mRNA surveillance and transport factors
     Transport factors
       EJC complex
       TREX complex
       TREX-2 complex
       Nuclear pore complex
       Ran-mediated transport factors
         5901 RAN; RAN, member RAS oncogene family
         23519 ANP32D; acidic nuclear phosphoprotein 32 family member D
         23520 ANP32C; acidic nuclear phosphoprotein 32 family member C
         8125 ANP32A; acidic nuclear phosphoprotein 32 family member A
         10541 ANP32B; acidic nuclear phosphoprotein 32 family member B
         8741 TNFSF13; TNF superfamily member 13
         1994 ELAVL1; ELAV like RNA binding protein 1
         1993 ELAVL2; ELAV like RNA binding protein 2
         1995 ELAVL3; ELAV like RNA binding protein 3
         1996 ELAVL4; ELAV like RNA binding protein 4
         23197 FAF2; Fas associated factor family member 2
         7415 VCP; valosin containing protein
         79609 VCPKMT; valosin containing protein lysine methyltransferase
         30000 TNPO2; transportin 2
         7514 XPO1; exportin 1
         23039 XPO7; exportin 7
         64901 RANBP17; RAN binding protein 17
         5905 RANGAP1; Ran GTPase activating protein 1
         8148 TAF15; TATA-box binding protein associated factor 15
K07936 RAN; GTP-binding nuclear protein Ran 
K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D 
K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D 
K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D 
K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B 
K05475 TNFSF13; tumor necrosis factor ligand superfamily member 13 
K13088 ELAVL1; ELAV-like protein 1 
K13208 ELAVL2_3_4; ELAV like protein 2/3/4 
K13208 ELAVL2_3_4; ELAV like protein 2/3/4 
K13208 ELAVL2_3_4; ELAV like protein 2/3/4 
K18726 FAF2; FAS-associated factor 2 
K13525 VCP; transitional endoplasmic reticulum ATPase 
K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-] 
K18727 TNPO2; transportin-2 
K14290 XPO1; exportin-1 
K18460 XPO7; exportin-7 
K24115 RANBP17; Ran-binding protein 17 
K14319 RANGAP1; Ran GTPase-activating protein 1 
K14651 TAF15; transcription initiation factor TFIID subunit 15 
       eIF4F and regulatory proteins
       Other transport factors
     Surveillance factors
     Factors involved in mRNA localization
     mRNA cycle factors
       Common to processing body (P body) and stress granule
       P-body specific factors
       Stress granule specific factors
         7073 TIAL1; TIA1 cytotoxic granule associated RNA binding protein like 1
         7072 TIA1; TIA1 cytotoxic granule associated RNA binding protein
         26986 PABPC1; poly(A) binding protein cytoplasmic 1
         140886 PABPC5; poly(A) binding protein cytoplasmic 5
         5042 PABPC3; poly(A) binding protein cytoplasmic 3
         645974 PABPC1L2B; poly(A) binding protein cytoplasmic 1 like 2B
         80336 PABPC1L; poly(A) binding protein cytoplasmic 1 like
         340529 PABPC1L2A; poly(A) binding protein cytoplasmic 1 like 2A
         8761 PABPC4; poly(A) binding protein cytoplasmic 4
         132430 PABPC4L; poly(A) binding protein cytoplasmic 4 like
         27067 STAU2; staufen double-stranded RNA binding protein 2
         6780 STAU1; staufen double-stranded RNA binding protein 1
         2332 FMR1; FMRP translational regulator 1
         8087 FXR1; FMR1 autosomal homolog 1
         9513 FXR2; FMR1 autosomal homolog 2
         81030 ZBP1; Z-DNA binding protein 1
         1994 ELAVL1; ELAV like RNA binding protein 1
         10146 G3BP1; G3BP stress granule assembly factor 1
         83939 EIF2A; eukaryotic translation initiation factor 2A
         8662 EIF3B; eukaryotic translation initiation factor 3 subunit B
         1973 EIF4A1; eukaryotic translation initiation factor 4A1
         1974 EIF4A2; eukaryotic translation initiation factor 4A2
         9775 EIF4A3; eukaryotic translation initiation factor 4A3
         1975 EIF4B; eukaryotic translation initiation factor 4B
         8672 EIF4G3; eukaryotic translation initiation factor 4 gamma 3
         1981 EIF4G1; eukaryotic translation initiation factor 4 gamma 1
         1982 EIF4G2; eukaryotic translation initiation factor 4 gamma 2
         6197 RPS6KA3; ribosomal protein S6 kinase A3
         6195 RPS6KA1; ribosomal protein S6 kinase A1
         6196 RPS6KA2; ribosomal protein S6 kinase A2
         27330 RPS6KA6; ribosomal protein S6 kinase A6
         10399 RACK1; receptor for activated C kinase 1
         7186 TRAF2; TNF receptor associated factor 2
         10482 NXF1; nuclear RNA export factor 1
         56001 NXF2; nuclear RNA export factor 2
         728343 NXF2B; nuclear RNA export factor 2B
         55998 NXF5; nuclear RNA export factor 5
         56000 NXF3; nuclear RNA export factor 3
         10013 HDAC6; histone deacetylase 6
         81550 TDRD3; tudor domain containing 3
         113251 LARP4; La ribonucleoprotein 4
         23185 LARP4B; La ribonucleoprotein 4B
K13201 TIA1; nucleolysin TIA-1/TIAR 
K13201 TIA1; nucleolysin TIA-1/TIAR 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K17597 STAU; double-stranded RNA-binding protein Staufen 
K17597 STAU; double-stranded RNA-binding protein Staufen 
K15516 FMR; fragile X mental retardation protein 
K15516 FMR; fragile X mental retardation protein 
K15516 FMR; fragile X mental retardation protein 
K12965 ZBP1; Z-DNA binding protein 1 
K13088 ELAVL1; ELAV-like protein 1 
K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:3.6.4.12 3.6.4.13] 
K15026 EIF2A; translation initiation factor 2A 
K03253 EIF3B; translation initiation factor 3 subunit B 
K03257 EIF4A; translation initiation factor 4A 
K03257 EIF4A; translation initiation factor 4A 
K13025 EIF4A3; ATP-dependent RNA helicase [EC:3.6.4.13] 
K03258 EIF4B; translation initiation factor 4B 
K03260 EIF4G; translation initiation factor 4G 
K03260 EIF4G; translation initiation factor 4G 
K03260 EIF4G; translation initiation factor 4G 
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27] 
K14284 NXF; nuclear RNA export factor 
K14284 NXF; nuclear RNA export factor 
K14284 NXF; nuclear RNA export factor 
K14284 NXF; nuclear RNA export factor 
K14284 NXF; nuclear RNA export factor 
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98] 
K18404 TDRD3; tudor domain-containing protein 3 
K18763 LARP4; la-related protein 4 
K18763 LARP4; la-related protein 4 
   mRNA degradation factors
 
 Prokaryotic type

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Last updated: September 2, 2020