Messenger RNA Biogenesis - Homo sapiens (human)

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     KO
 Eukaryotic type
   mRNA processing factors
   mRNA surveillance and transport factors
     Transport factors
     Surveillance factors
     Factors involved in mRNA localization
     mRNA cycle factors
       Common to processing body (P body) and stress granule
         54464 XRN1; 5'-3' exoribonuclease 1
         192669 AGO3; argonaute RISC catalytic component 3
         26523 AGO1; argonaute RISC component 1
         192670 AGO4; argonaute RISC component 4
         27161 AGO2; argonaute RISC catalytic component 2
         1977 EIF4E; eukaryotic translation initiation factor 4E
         9470 EIF4E2; eukaryotic translation initiation factor 4E family member 2
         253314 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B
         5976 UPF1; UPF1 RNA helicase and ATPase
         1654 DDX3X; DEAD-box helicase 3 X-linked
         8653 DDX3Y; DEAD-box helicase 3 Y-linked
         1656 DDX6; DEAD-box helicase 6
         399664 MEX3D; mex-3 RNA binding family member D
         51320 MEX3C; mex-3 RNA binding family member C
         84206 MEX3B; mex-3 RNA binding family member B
         92312 MEX3A; mex-3 RNA binding family member A
         10922 FASTK; Fas activated serine/threonine kinase
         149986 LSM14B; LSM family member 14B
         26065 LSM14A; LSM14A mRNA processing body assembly factor
         5093 PCBP1; poly(rC) binding protein 1
         5094 PCBP2; poly(rC) binding protein 2
         4904 YBX1; Y-box binding protein 1
         8994 LIMD1; LIM domains containing 1
         84962 AJUBA; ajuba LIM protein
         126374 WTIP; WT1 interacting protein
         339 APOBEC1; apolipoprotein B mRNA editing enzyme catalytic subunit 1
         164668 APOBEC3H; apolipoprotein B mRNA editing enzyme catalytic subunit 3H
         200316 APOBEC3F; apolipoprotein B mRNA editing enzyme catalytic subunit 3F
         100913187 APOBEC3A_B; APOBEC3A and APOBEC3B deletion hybrid
         140564 APOBEC3D; apolipoprotein B mRNA editing enzyme catalytic subunit 3D
         200315 APOBEC3A; apolipoprotein B mRNA editing enzyme catalytic subunit 3A
         27350 APOBEC3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C
         60489 APOBEC3G; apolipoprotein B mRNA editing enzyme catalytic subunit 3G
         9582 APOBEC3B; apolipoprotein B mRNA editing enzyme catalytic subunit 3B
         4343 MOV10; Mov10 RISC complex RNA helicase
         55629 PNRC2; proline rich nuclear receptor coactivator 2
         3842 TNPO1; transportin 1
         23049 SMG1; SMG1 nonsense mediated mRNA decay associated PI3K related kinase
         23381 SMG5; SMG5 nonsense mediated mRNA decay factor
         23293 SMG6; SMG6 nonsense mediated mRNA decay factor
         9887 SMG7; SMG7 nonsense mediated mRNA decay factor
         7538 ZFP36; ZFP36 ring finger protein
         677 ZFP36L1; ZFP36 ring finger protein like 1
         678 ZFP36L2; ZFP36 ring finger protein like 2
         389421 LIN28B; lin-28 homolog B
         79727 LIN28A; lin-28 homolog A
         3064 HTT; huntingtin
         10526 IPO8; importin 8
         80114 BICC1; BicC family RNA binding protein 1
         220988 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3
         3178 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1
         144983 HNRNPA1L2; heterogeneous nuclear ribonucleoprotein A1 like 2
         5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
         5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
         5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
         23367 LARP1; La ribonucleoprotein 1, translational regulator
         55132 LARP1B; La ribonucleoprotein 1B
         11273 ATXN2L; ataxin 2 like
         6311 ATXN2; ataxin 2
K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
K11593 ELF2C; eukaryotic translation initiation factor 2C 
K11593 ELF2C; eukaryotic translation initiation factor 2C 
K11593 ELF2C; eukaryotic translation initiation factor 2C 
K11593 ELF2C; eukaryotic translation initiation factor 2C 
K03259 EIF4E; translation initiation factor 4E 
K03259 EIF4E; translation initiation factor 4E 
K03259 EIF4E; translation initiation factor 4E 
K14326 UPF1; regulator of nonsense transcripts 1 [EC:3.6.4.-] 
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13] 
K17642 DDX3Y; ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13] 
K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13] 
K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8] 
K18749 LSM14; protein LSM14 
K18749 LSM14; protein LSM14 
K12889 PCBP1; poly(rC)-binding protein 1 
K13162 PCBP2; poly(rC)-binding protein 2 
K09276 YBX1; Y-box-binding protein 1 
K16682 AJUBA; LIM domain-containing protein 
K16682 AJUBA; LIM domain-containing protein 
K16682 AJUBA; LIM domain-containing protein 
K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36] 
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-] 
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-] 
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-] 
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-] 
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-] 
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-] 
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-] 
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-] 
K18422 MOV10; helicase MOV-10 [EC:3.6.4.13] 
K18751 PNRC2; proline-rich nuclear receptor coactivator 2 
K18752 TNPO1; transportin-1 
K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1] 
K11125 SMG5; protein SMG5 
K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
K14409 SMG7; protein SMG7 
K15308 TTP; tristetraprolin 
K18753 ZFP36L; butyrate response factor 
K18753 ZFP36L; butyrate response factor 
K18754 LIN28; protein lin-28 
K18754 LIN28; protein lin-28 
K04533 HD; huntingtin 
K18755 IPO8; importin-8 
K18756 BICC1; protein bicaudal C 
K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K18757 LARP1; la-related protein 1 
K18757 LARP1; la-related protein 1 
K23625 ATXN2_2L; ataxin 2/2L 
K23625 ATXN2_2L; ataxin 2/2L 
       P-body specific factors
       Stress granule specific factors
   mRNA degradation factors
 
 Prokaryotic type

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Last updated: September 2, 2020