Chromosome and Associated Proteins - Homo sapiens (human)

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     KO
 Eukaryotic type
   Sister chromatid cohesion proteins
   Meiosis-specific proteins
   Nucleosome assembly factors
   Histone modification proteins
     HATs (histone acetyltransferases)
     HAT complexes
     HDACs (histone deacetylases)
       Class I HDACs
         3065 HDAC1; histone deacetylase 1
         3066 HDAC2; histone deacetylase 2
         8841 HDAC3; histone deacetylase 3
         55869 HDAC8; histone deacetylase 8
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98] 
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98] 
       Class II HDACs
       SIRTs (sirtuins, class III HDACs)
       Class IV HDACs
     HDAC complexes
       Sin3A-HDAC complex
         3065 HDAC1; histone deacetylase 1
         3066 HDAC2; histone deacetylase 2
         25942 SIN3A; SIN3 transcription regulator family member A
         5928 RBBP4; RB binding protein 4, chromatin remodeling factor
         5931 RBBP7; RB binding protein 7, chromatin remodeling factor
         64426 SUDS3; SDS3 homolog, SIN3A corepressor complex component
         8819 SAP30; Sin3A associated protein 30
         79685 SAP30L; SAP30 like
         10284 SAP18; Sin3A associated protein 18
         79595 SAP130; Sin3A associated protein 130
         100316904 SAP25; Sin3A associated protein 25
         5926 ARID4A; AT-rich interaction domain 4A
         51742 ARID4B; AT-rich interaction domain 4B
         25855 BRMS1; BRMS1 transcriptional repressor and anoikis regulator
         84312 BRMS1L; BRMS1 like transcriptional repressor
         3621 ING1; inhibitor of growth family member 1
         3622 ING2; inhibitor of growth family member 2
         58516 SINHCAF; SIN3-HDAC complex associated factor
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K11644 SIN3A; paired amphipathic helix protein Sin3a 
K10752 RBBP4; histone-binding protein RBBP4 
K11659 RBBP7; histone-binding protein RBBP7 
K19201 SUDS3; Sin3 histone deacetylase corepressor complex component SDS3 
K19202 SAP30; histone deacetylase complex subunit SAP30 
K19202 SAP30; histone deacetylase complex subunit SAP30 
K14324 SAP18; histone deacetylase complex subunit SAP18 
K19192 SAP130; histone deacetylase complex subunit SAP130 
K19193 SAP25; histone deacetylase complex subunit SAP25 
K19194 ARID4A; AT-rich interactive domain-containing protein 4A 
K19195 ARID4B; AT-rich interactive domain-containing protein 4B 
K19196 BRMS1; breast cancer metastasis-suppressor 1 and related proteins 
K19196 BRMS1; breast cancer metastasis-suppressor 1 and related proteins 
K19197 ING1; inhibitor of growth protein 1 
K19198 ING2; inhibitor of growth protein 2 
K26090 SINHCAF; SIN3-HDAC complex-associated factor 
       BRAF-HDAC complex
         3065 HDAC1; histone deacetylase 1
         3066 HDAC2; histone deacetylase 2
         10362 HMG20B; high mobility group 20B
         23028 KDM1A; lysine demethylase 1A
         23186 RCOR1; REST corepressor 1
         51317 PHF21A; PHD finger protein 21A
         9203 ZMYM3; zinc finger MYM-type containing 3
         9202 ZMYM4; zinc finger MYM-type containing 4
         7750 ZMYM2; zinc finger MYM-type containing 2
         7764 ZNF217; zinc finger protein 217
         23199 GSE1; Gse1 coiled-coil protein
         2969 GTF2I; general transcription factor IIi
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K24650 HMG20B; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related 
K11450 KDM1A; [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66] 
K11829 RCOR1; REST corepressor 1 
K24651 PHF21A; PHD finger protein 21A 
K24675 ZMYM2_3_4; zinc finger MYM-type protein 2/3/4 
K24675 ZMYM2_3_4; zinc finger MYM-type protein 2/3/4 
K24675 ZMYM2_3_4; zinc finger MYM-type protein 2/3/4 
K27275 ZNF217; zinc finger protein 217 
K27276 GSE1; genetic suppressor element 1 
K03121 TFII-I; transcription initiation factor TFII-I 
       REST complex
         5978 REST; RE1 silencing transcription factor
         25942 SIN3A; SIN3 transcription regulator family member A
         23309 SIN3B; SIN3 transcription regulator family member B
         3065 HDAC1; histone deacetylase 1
         3066 HDAC2; histone deacetylase 2
         23186 RCOR1; REST corepressor 1
         283248 RCOR2; REST corepressor 2
         55758 RCOR3; REST corepressor 3
         23028 KDM1A; lysine demethylase 1A
         6595 SMARCA2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
         6597 SMARCA4; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
         10919 EHMT2; euchromatic histone lysine methyltransferase 2
         79813 EHMT1; euchromatic histone lysine methyltransferase 1
K09222 REST; RE1-silencing transcription factor 
K11644 SIN3A; paired amphipathic helix protein Sin3a 
K23213 SIN3B; paired amphipathic helix protein Sin3b 
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K11829 RCOR1; REST corepressor 1 
K26242 RCOR2_3; REST corepressor 2/3 
K26242 RCOR2_3; REST corepressor 2/3 
K11450 KDM1A; [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66] 
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-] 
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-] 
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355] 
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355] 
       SHIP complex
         3065 HDAC1; histone deacetylase 1
         3066 HDAC2; histone deacetylase 2
         3635 INPP5D; inositol polyphosphate-5-phosphatase D
         3306 HSPA2; heat shock protein family A (Hsp70) member 2
         146212 KCTD19; potassium channel tetramerization domain containing 19
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K03084 SHIP1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86] 
K26598 HSPA2; heat shock 70kDa protein 2 
K26581 KCTD19; BTB/POZ domain-containing protein KCTD19 
       MiDAC complex
         3065 HDAC1; histone deacetylase 1
         3066 HDAC2; histone deacetylase 2
         91748 MIDEAS; mitotic deacetylase associated SANT domain protein
         116092 DNTTIP1; deoxynucleotidyltransferase terminal interacting protein 1
         55809 TRERF1; transcriptional regulating factor 1
         84215 ZNF541; zinc finger protein 541
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K26582 MIDEAS; mitotic deacetylase-associated SANT domain protein 
K08707 DNTTIP1; deoxynucleotidyltransferase terminal-interacting protein 1 
K26583 TRERF1; transcriptional-regulating factor 1 
K26584 ZNF541; zinc finger protein 541 
       SMART complex
       Other HDAC associated proteins
     HMTs (histone methyltransferases)
     HMT complexes
     Histone demethylases
     Polycomb repressive complex (PRC) and associated proteins
       Canonical PRC1 (PRC1.2/1.4)
       Noncanonical PRC1 (PRC1.1)
       Noncanonical PRC1 (PRC1.3/1.5)
       Noncanonical PRC1 (PRC1.6)
         6045 RNF2; ring finger protein 2
         6015 RING1; ring finger protein 1
         84108 PCGF6; polycomb group ring finger 6
         23429 RYBP; RING1 and YY1 binding protein
         10138 YAF2; YY1 associated factor 2
         1876 E2F6; E2F transcription factor 6
         7027 TFDP1; transcription factor Dp-1
         4149 MAX; MYC associated factor X
         23269 MGA; MAX dimerization protein MGA
         26013 L3MBTL1; L3MBTL histone methyl-lysine binding protein 1
         84456 L3MBTL3; L3MBTL histone methyl-lysine binding protein 3
         83746 L3MBTL2; L3MBTL histone methyl-lysine binding protein 2
         91133 L3MBTL4; L3MBTL histone methyl-lysine binding protein 4
         11335 CBX3; chromobox 3
         11091 WDR5; WD repeat domain 5
         54554 WDR5B; WD repeat domain 5B
         3065 HDAC1; histone deacetylase 1
         3066 HDAC2; histone deacetylase 2
K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27] 
K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27] 
K11470 PCGF6; polycomb group RING finger protein 6 
K11469 RYBP; RING1 and YY1-binding protein 
K11468 YAF2; YY1-associated factor 2 
K09390 E2F6; transcription factor E2F6 
K04683 TFDP1; transcription factor Dp-1 
K04453 MAX; Max protein 
K23399 MGA; MAX gene-associated protein 
K24387 L3MBTL; lethal(3)malignant brain tumor-like protein 
K24387 L3MBTL; lethal(3)malignant brain tumor-like protein 
K24387 L3MBTL; lethal(3)malignant brain tumor-like protein 
K24387 L3MBTL; lethal(3)malignant brain tumor-like protein 
K11586 CBX3; chromobox protein 3 
K14963 WDR5; COMPASS component SWD3 
K14963 WDR5; COMPASS component SWD3 
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
       PRC2.1
       PRC2.2
       PR-DUB complex
       Other PRC associated proteins
     Sir proteins
     Other histone modification proteins
   Chromosome condensation proteins
   Centromeric chromatin formation proteins
   Heterochromatin formation proteins
     HP1 (heterochromatin protein 1)
     MBPs (metylated DNA binding proteins)
     Other heterochromatin formation proteins
       546 ATRX; ATRX chromatin remodeler
       1786 DNMT1; DNA methyltransferase 1
       1788 DNMT3A; DNA methyltransferase 3 alpha
       1789 DNMT3B; DNA methyltransferase 3 beta
       29947 DNMT3L; DNA methyltransferase 3 like
       3065 HDAC1; histone deacetylase 1
       3066 HDAC2; histone deacetylase 2
       25942 SIN3A; SIN3 transcription regulator family member A
       1107 CHD3; chromodomain helicase DNA binding protein 3
       1108 CHD4; chromodomain helicase DNA binding protein 4
       5928 RBBP4; RB binding protein 4, chromatin remodeling factor
       55729 ATF7IP; activating transcription factor 7 interacting protein
       80063 ATF7IP2; activating transcription factor 7 interacting protein 2
       9869 SETDB1; SET domain bifurcated histone lysine methyltransferase 1
       83852 SETDB2; SET domain bifurcated histone lysine methyltransferase 2
       6839 SUV39H1; SUV39H1 histone lysine methyltransferase
       79723 SUV39H2; SUV39H2 histone lysine methyltransferase
       3930 LBR; lamin B receptor
       57167 SALL4; spalt like transcription factor 4
       6299 SALL1; spalt like transcription factor 1
       6297 SALL2; spalt like transcription factor 2
       27164 SALL3; spalt like transcription factor 3
       54737 MPHOSPH8; M-phase phosphoprotein 8
       51535 PPHLN1; periphilin 1
       23272 TASOR; transcription activation suppressor
       23394 ADNP; activity dependent neuroprotector homeobox
       27245 AHDC1; AT-hook DNA binding motif containing 1
       283489 CHAMP1; chromosome alignment maintaining phosphoprotein 1
       23126 POGZ; pogo transposable element derived with ZNF domain
       23347 SMCHD1; structural maintenance of chromosomes flexible hinge domain containing 1
       55791 LRIF1; ligand dependent nuclear receptor interacting factor 1
       100506736 SLFN12L; schlafen family member 12 like
       55106 SLFN12; schlafen family member 12
       79968 WDR76; WD repeat domain 76
K10779 ATRX; transcriptional regulator ATRX 
K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37] 
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37] 
K17400 DNMT3L; DNA (cytosine-5)-methyltransferase 3-like 
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K11644 SIN3A; paired amphipathic helix protein Sin3a 
K11642 CHD3; chromodomain-helicase-DNA-binding protein 3 [EC:5.6.2.-] 
K11643 CHD4; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-] 
K10752 RBBP4; histone-binding protein RBBP4 
K25802 ATF7IP; activating transcription factor 7-interacting protein 
K25802 ATF7IP; activating transcription factor 7-interacting protein 
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366] 
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355] 
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355] 
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355] 
K19532 LBR; Delta14-sterol reductase (lamin-B receptor) [EC:1.3.1.70] 
K19871 SALL; sal-like protein 
K19871 SALL; sal-like protein 
K19871 SALL; sal-like protein 
K19871 SALL; sal-like protein 
K21871 MPHOSPH8; M-phase phosphoprotein 8 
K21872 PPHLN1; periphilin-1 
K21873 FAM208A; protein TASOR 
K22591 ADNP; activity-dependent neuroprotector homeobox protein 
K22592 AHDC1; AT-hook DNA-binding motif-containing protein 1 
K22593 CHAMP1; chromosome alignment-maintaining phosphoprotein 1 
K22594 POGZ; pogo transposable element with ZNF domain 
K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1 
K23220 LRIF1; ligand-dependent nuclear receptor-interacting factor 1 
K24457 SLFN12; schlafen family member 12 
K24457 SLFN12; schlafen family member 12 
K24755 WDR76; WD repeat-containing protein 76 
   Gene silencing
   Centrosome formation proteins
   Sister chromatid separation proteins
   Chromatin remodeling factors
     BAF complex
     PBAF complex
     GBAF(ncBAF) complex
     CHRAC complex
     RSF complex
     WICH complex
     B-WICH complex
     NORC complex
     BRF complex
     NuRD complex
       3065 HDAC1; histone deacetylase 1
       3066 HDAC2; histone deacetylase 2
       1107 CHD3; chromodomain helicase DNA binding protein 3
       1108 CHD4; chromodomain helicase DNA binding protein 4
       5928 RBBP4; RB binding protein 4, chromatin remodeling factor
       5931 RBBP7; RB binding protein 7, chromatin remodeling factor
       9219 MTA2; metastasis associated 1 family member 2
       9112 MTA1; metastasis associated 1
       57504 MTA3; metastasis associated 1 family member 3
       53615 MBD3; methyl-CpG binding domain protein 3
       54815 GATAD2A; GATA zinc finger domain containing 2A
       57459 GATAD2B; GATA zinc finger domain containing 2B
       84295 PHF6; PHD finger protein 6
       8099 CDK2AP1; cyclin dependent kinase 2 associated protein 1
       10263 CDK2AP2; cyclin dependent kinase 2 associated protein 2
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98] 
K11642 CHD3; chromodomain-helicase-DNA-binding protein 3 [EC:5.6.2.-] 
K11643 CHD4; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-] 
K10752 RBBP4; histone-binding protein RBBP4 
K11659 RBBP7; histone-binding protein RBBP7 
K11660 MTA; metastasis-associated protein MTA 
K11660 MTA; metastasis-associated protein MTA 
K11660 MTA; metastasis-associated protein MTA 
K11591 MBD3; methyl-CpG-binding domain protein 3 
K23194 GATAD2; transcriptional repressor p66 
K23194 GATAD2; transcriptional repressor p66 
K23310 PHF6; PHD finger protein 6 
K26454 CDK2AP1; cyclin-dependent kinase 2-associated protein 1 
K26455 CDK2AP2; cyclin-dependent kinase 2-associated protein 2 
     NuRF complex
     NuRF complex (fruit fly)
     CERF complex
     SRCAP complex
     INO80 complex
     INO80 complex (yeast)
     RSC complex
     SWI/SNF complex
     SWR1 complex
     ASTRA complex
     Other chromatin remodeling factors
 
 Prokaryotic type

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Last updated: March 14, 2024