DNA Repair and Recombination Proteins - Homo sapiens (human)

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     KO
 Eukaryotic type
   SSBR (single strand breaks repair)
   DSBR (double strand breaks repair)
   TLS (translesion DNA synthesis) factors
   Check point factors
     Rad9-Hus1-Rad1 complex
     HRAD17(Rad24)-RFC complex
     Rad17-Mec3-Ddc1 complex
     FPC (fork protection complex)
     Triple T complex
     BAG6-UBL4A-GET4 complex
     Other check point factors
       545 ATR; ATR serine/threonine kinase
       84126 ATRIP; ATR interacting protein
       472 ATM; ATM serine/threonine kinase
       7157 TP53; tumor protein p53
       1111 CHEK1; checkpoint kinase 1
       11200 CHEK2; checkpoint kinase 2
       993 CDC25A; cell division cycle 25A
       994 CDC25B; cell division cycle 25B
       995 CDC25C; cell division cycle 25C
       7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
       7529 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
       10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
       7533 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
       7532 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
       7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
       89797 NAV2; neuron navigator 2
       7465 WEE1; WEE1 G2 checkpoint kinase
       494551 WEE2; WEE2 oocyte meiosis inhibiting kinase
       5187 PER1; period circadian regulator 1
       8864 PER2; period circadian regulator 2
       8863 PER3; period circadian regulator 3
       9656 MDC1; mediator of DNA damage checkpoint 1
       5358 PLS3; plastin 3
       64782 AEN; apoptosis enhancing nuclease
       1263 PLK3; polo like kinase 3
       126520 PLK5; polo like kinase 5 (inactive)
       341676 NEK5; NIMA related kinase 5
       4750 NEK1; NIMA related kinase 1
       6787 NEK4; NIMA related kinase 4
       152110 NEK10; NIMA related kinase 10
       79858 NEK11; NIMA related kinase 11
       29980 DONSON; DNA replication fork stabilization factor DONSON
       163782 KANK4; KN motif and ankyrin repeat domains 4
       23189 KANK1; KN motif and ankyrin repeat domains 1
       256949 KANK3; KN motif and ankyrin repeat domains 3
       25959 KANK2; KN motif and ankyrin repeat domains 2
       100144748 KLLN; killin, p53 regulated DNA replication inhibitor
       91607 SLFN11; schlafen family member 11
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1] 
K10905 ATRIP; ATR interacting protein 
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1] 
K04451 TP53; tumor protein p53 
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] 
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1] 
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48] 
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48] 
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48] 
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
K16198 YWHAG_H; 14-3-3 protein gamma/eta 
K16198 YWHAG_H; 14-3-3 protein gamma/eta 
K06630 YWHAE; 14-3-3 protein epsilon 
K19483 NAV2; neuron navigator 2 [EC:3.6.4.12] 
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] 
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] 
K21944 PER1; period circadian protein 1 
K02633 PER2; period circadian protein 2 
K21945 PER3; period circadian protein 3 
K20780 MDC1; mediator of DNA damage checkpoint protein 1 
K17336 PLS3; plastin-3 
K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-] 
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21] 
K19596 PLK5; inactive serine/threonine-protein kinase PLK5 
K08857 NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1] 
K08857 NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1] 
K08857 NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1] 
K20879 NEK10; NIMA (never in mitosis gene a)-related kinase 10 [EC:2.7.11.1] 
K20880 NEK11; NIMA (never in mitosis gene a)-related kinase 11 [EC:2.7.11.1] 
K22422 DONSON; protein downstream neighbor of Son 
K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
K23389 KLLN; killin 
K24458 SLFN11; schlafen family member 11 [EC:3.6.-.-] 
   Other factors with a suspected DNA repair function
 
 Prokaryotic type

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Last updated: October 14, 2020