Ubiquitin System - Homo sapiens (human)

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 Ubiquitins and ubiquitin-like proteins
 Ubiquitin-activating enzymes (E1)
 Ubiquitin-conjugating enzymes (E2)
 Ubiquitin ligases (E3)
   HECT type E3
   U-box type E3
   Single Ring-finger type E3
     BRE1 proteins
     CBL proteins
     SINA (Seven in absentia) proteins
     Ligand of Numb proteins
     March proteins
     MDM2/MDM4 proteins
     NFX1 proteins
     Pellino proteins
     Peripheral membrane proteins
     RBR proteins
     TRAF proteins
       7186 TRAF2; TNF receptor associated factor 2
       7188 TRAF5; TNF receptor associated factor 5
       7189 TRAF6; TNF receptor associated factor 6
       84231 TRAF7; TNF receptor associated factor 7
K03173 TRAF2; TNF receptor-associated factor 2 [EC:] 
K09849 TRAF5; TNF receptor-associated factor 5 
K03175 TRAF6; TNF receptor-associated factor 6 [EC:] 
K10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:] 
     TRIM/RBCC proteins
     UBR box proteins
     ATL proteins
     Other single Ring-finger type E3
   Atypical E3
   UBL E3 ligases
   Multi subunit Ring-finger type E3
 Deubiquitinating enzyme (DUB)

Last updated: September 3, 2020