Membrane Trafficking - Homo sapiens (human)

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     KO
 Exocytosis
 
 SNARE
 
 Endocytosis
   Clathrin-mediated endocytosis
     Clathrin
     Dynamin
       1759 DNM1; dynamin 1
       26052 DNM3; dynamin 3
       1785 DNM2; dynamin 2
       10059 DNM1L; dynamin 1 like
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5] 
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5] 
K23484 DNM2; dynamin 2 [EC:3.6.5.5] 
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5] 
     AP-2 complex
     Other core components
     Low-density lipoprotein receptor (LDLR) family proteins
     LDLR adaptor proteins
     GPCR adaptor proteins
     Receptor tyrosine kinase (RTK) adaptor proteins
     Inositol 5-phosphatases
     Kinases
     Ubiquitin E3 ligases
     Others
   Lipid raft mediated endocytosis
     Caveolin-mediated endocytosis
       857 CAV1; caveolin 1
       858 CAV2; caveolin 2
       859 CAV3; caveolin 3
       1759 DNM1; dynamin 1
       26052 DNM3; dynamin 3
       1785 DNM2; dynamin 2
       10059 DNM1L; dynamin 1 like
       6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
       5578 PRKCA; protein kinase C alpha
       50618 ITSN2; intersectin 2
       6453 ITSN1; intersectin 1
       23209 MLC1; modulator of VRAC current 1
K06278 CAV1; caveolin 1 
K12958 CAV2; caveolin 2 
K12959 CAV3; caveolin 3 
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5] 
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5] 
K23484 DNM2; dynamin 2 [EC:3.6.5.5] 
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5] 
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2] 
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13] 
K20045 ITSN; intersectin 
K20045 ITSN; intersectin 
K20070 MLC1; membrane protein MLC1 
     Flotillin-dependent endocytosis
     GRAF1-dependent endocytosis
     Arf6-dependent endocytosis
     RhoA-dependent endocytosis
       387 RHOA; ras homolog family member A
       1759 DNM1; dynamin 1
       26052 DNM3; dynamin 3
       1785 DNM2; dynamin 2
       10059 DNM1L; dynamin 1 like
       84894 LINGO1; leucine rich repeat and Ig domain containing 1
       158038 LINGO2; leucine rich repeat and Ig domain containing 2
       645191 LINGO3; leucine rich repeat and Ig domain containing 3
       339398 LINGO4; leucine rich repeat and Ig domain containing 4
K04513 RHOA; Ras homolog gene family, member A 
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5] 
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5] 
K23484 DNM2; dynamin 2 [EC:3.6.5.5] 
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5] 
K23533 LINGO; leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 
K23533 LINGO; leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 
K23533 LINGO; leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 
K23533 LINGO; leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 
   Phagocytosis
   Macropinocytosis
   Bin/Amphiphysin/Rvs (BAR) family proteins
   Rab GTPases and associated proteins
   Arf GTPases and associated proteins
   Others
 
 Endosome - Lysosome transport
 
 Protein recycling
 
 Endosome - Golgi transport
 
 Endoplasmic reticulum (ER) - Golgi transport
 
 Autophagy
 
 Others

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Last updated: October 23, 2020