Membrane Trafficking - Homo sapiens (human)

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     KO
 Exocytosis
 
 SNARE
   Syntaxin (Qa)
   SNAP-25[N] (Qb)
   SNAP-25[C] (Qc)
   SNAP-25 (Qb,c)
   VAMP, Ykt6, Sec22 (R)
   SNARE associated proteins
     Syntaxin-binding proteins
     Palmitoyltransferases
     Others
       23557 SNAPIN; SNAP associated protein
       57393 CLTRN; collectrin, amino acid transport regulator
       4905 NSF; N-ethylmaleimide sensitive factor, vesicle fusing ATPase
       8775 NAPA; NSF attachment protein alpha
       8774 NAPG; NSF attachment protein gamma
       23054 NCOA6; nuclear receptor coactivator 6
       2596 GAP43; growth associated protein 43
       1742 DLG4; discs large MAGUK scaffold protein 4
       8723 SNX4; sorting nexin 4
       64083 GOLPH3; golgi phosphoprotein 3
       55204 GOLPH3L; golgi phosphoprotein 3 like
       9842 PLEKHM1; pleckstrin homology and RUN domain containing M1
       1861 TOR1A; torsin family 1 member A
       27348 TOR1B; torsin family 1 member B
       23623 RUSC1; RUN and SH3 domain containing 1
       7415 VCP; valosin containing protein
       55968 NSFL1C; NSFL1 cofactor
       137886 UBXN2B; UBX domain protein 2B
K20002 SNAPIN; SNARE-associated protein Snapin 
K20004 TMEM27; collectrin 
K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6] 
K15296 NAPA; alpha-soluble NSF attachment protein 
K21198 NAPG; gamma-soluble NSF attachment protein 
K14971 NCOA6; nuclear receptor coactivator 6 
K20041 GAP43; neuromodulin 
K11828 DLG4; discs large protein 4 
K17919 SNX4; sorting nexin-4 
K15620 GOLPH3; golgi phosphoprotein 3 
K15620 GOLPH3; golgi phosphoprotein 3 
K23282 PLEKHM1; pleckstrin homology domain-containing family M member 1 
K22990 TOR1; torsin-1 
K22990 TOR1; torsin-1 
K23283 RUSC1; RUN and SH3 domain-containing protein 1 
K13525 VCP; transitional endoplasmic reticulum ATPase 
K14012 NSFL1C; UBX domain-containing protein 1 
K24347 UBXN2B; UBX domain-containing protein 2B 
 
 Endocytosis
   Clathrin-mediated endocytosis
     Clathrin
     Dynamin
     AP-2 complex
     Other core components
     Low-density lipoprotein receptor (LDLR) family proteins
     LDLR adaptor proteins
       26119 LDLRAP1; low density lipoprotein receptor adaptor protein 1
       1600 DAB1; DAB adaptor protein 1
       1601 DAB2; DAB adaptor protein 2
       8650 NUMB; NUMB endocytic adaptor protein
       9253 NUMBL; NUMB like endocytic adaptor protein
       322 APBB1; amyloid beta precursor protein binding family B member 1
       320 APBA1; amyloid beta precursor protein binding family A member 1
       321 APBA2; amyloid beta precursor protein binding family A member 2
       9479 MAPK8IP1; mitogen-activated protein kinase 8 interacting protein 1
       23542 MAPK8IP2; mitogen-activated protein kinase 8 interacting protein 2
       23396 PIP5K1C; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
       8394 PIP5K1A; phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
       8395 PIP5K1B; phosphatidylinositol-4-phosphate 5-kinase type 1 beta
       1742 DLG4; discs large MAGUK scaffold protein 4
       126326 GIPC3; GIPC PDZ domain containing family member 3
       10755 GIPC1; GIPC PDZ domain containing family member 1
       54810 GIPC2; GIPC PDZ domain containing family member 2
       55333 SYNJ2BP; synaptojanin 2 binding protein
       9270 ITGB1BP1; integrin subunit beta 1 binding protein 1
       9722 NOS1AP; nitric oxide synthase 1 adaptor protein
K12474 LDLRAP1; low density lipoprotein receptor adapter protein 1 
K20054 DAB1; disabled homolog 1 
K12475 DAB2; disabled homolog 2 
K06057 NUMBL; numb 
K06057 NUMBL; numb 
K04529 APBB1; amyloid beta A4 precursor protein-binding family B member 1 
K04531 APBA1; amyloid beta A4 precursor protein-binding family A member 1 
K20055 APBA2; amyloid beta A4 precursor protein-binding family A member 2 
K04434 MAPK8IP1; mitogen-activated protein kinase 8 interacting protein 1 
K04435 MAPK8IP2; mitogen-activated protein kinase 8 interacting protein 2 
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] 
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] 
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] 
K11828 DLG4; discs large protein 4 
K20056 GIPC; PDZ domain-containing protein GIPC 
K20056 GIPC; PDZ domain-containing protein GIPC 
K20056 GIPC; PDZ domain-containing protein GIPC 
K20057 SYNJ2BP; synaptojanin-2-binding protein 
K20058 ITGB1BP1; integrin beta-1-binding protein 1 
K16513 NOS1AP; carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein 
     GPCR adaptor proteins
     Receptor tyrosine kinase (RTK) adaptor proteins
     Inositol 5-phosphatases
     Kinases
     Ubiquitin E3 ligases
     Others
   Lipid raft mediated endocytosis
   Phagocytosis
   Macropinocytosis
   Bin/Amphiphysin/Rvs (BAR) family proteins
   Rab GTPases and associated proteins
   Arf GTPases and associated proteins
   Others
 
 Endosome - Lysosome transport
 
 Protein recycling
 
 Endosome - Golgi transport
 
 Endoplasmic reticulum (ER) - Golgi transport
 
 Autophagy
 
 Others

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Last updated: December 23, 2020