Membrane Trafficking - Homo sapiens (human)

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     KO
 Exocytosis
 
 SNARE
 
 Endocytosis
   Clathrin-mediated endocytosis
   Lipid raft mediated endocytosis
   Phagocytosis
   Macropinocytosis
   Bin/Amphiphysin/Rvs (BAR) family proteins
   Rab GTPases and associated proteins
   Arf GTPases and associated proteins
     Arf GTPases
     Arf associated proteins
       116983 ACAP3; ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
       23527 ACAP2; ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
       9744 ACAP1; ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
       116985 ARAP1; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
       116984 ARAP2; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
       64411 ARAP3; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
       64744 SMAP2; small ArfGAP2
       60682 SMAP1; small ArfGAP 1
       28964 GIT1; GIT ArfGAP 1
       9815 GIT2; GIT ArfGAP 2
       23362 PSD3; pleckstrin and Sec7 domain containing 3
       23550 PSD4; pleckstrin and Sec7 domain containing 4
       5662 PSD; pleckstrin and Sec7 domain containing
       84249 PSD2; pleckstrin and Sec7 domain containing 2
       23096 IQSEC2; IQ motif and Sec7 domain ArfGEF 2
       9922 IQSEC1; IQ motif and Sec7 domain ArfGEF 1
       440073 IQSEC3; IQ motif and Sec7 domain ArfGEF 3
       9265 CYTH3; cytohesin 3
       27128 CYTH4; cytohesin 4
       9266 CYTH2; cytohesin 2
       9267 CYTH1; cytohesin 1
       57465 TBC1D24; TBC1 domain family member 24
       55531 ELMOD1; ELMO domain containing 1
       255520 ELMOD2; ELMO domain containing 2
       84173 ELMOD3; ELMO domain containing 3
K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 
K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 
K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 
K18439 ARAP1; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 
K18440 ARAP2; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 
K12490 ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 
K12486 SMAP; stromal membrane-associated protein 
K12486 SMAP; stromal membrane-associated protein 
K05737 GIT1; G protein-coupled receptor kinase interactor 1 
K12487 GIT2; G protein-coupled receptor kinase interactor 2 
K12494 PSD; PH and SEC7 domain-containing protein 
K12494 PSD; PH and SEC7 domain-containing protein 
K12494 PSD; PH and SEC7 domain-containing protein 
K12494 PSD; PH and SEC7 domain-containing protein 
K12495 IQSEC; IQ motif and SEC7 domain-containing protein 
K12495 IQSEC; IQ motif and SEC7 domain-containing protein 
K12495 IQSEC; IQ motif and SEC7 domain-containing protein 
K18441 CYTH; cytohesin 
K18441 CYTH; cytohesin 
K18441 CYTH; cytohesin 
K18441 CYTH; cytohesin 
K21841 TBC1D24; TBC1 domain family member 24 
K23538 ELMOD; ELMO domain-containing protein 
K23538 ELMOD; ELMO domain-containing protein 
K23538 ELMOD; ELMO domain-containing protein 
   Others
 
 Endosome - Lysosome transport
 
 Protein recycling
 
 Endosome - Golgi transport
 
 Endoplasmic reticulum (ER) - Golgi transport
 
 Autophagy
 
 Others
   NADPH oxidases (Nox) and associated proteins
   Actin-binding proteins
   Mucins
   Rab GTPases of specific organelles
   Rho GTPase associated proteins
     Rho GTPase-activating proteins
       613 BCR; BCR activator of RhoGEF and GTPase
       29 ABR; ABR activator of RhoGEF and GTPase
       392 ARHGAP1; Rho GTPase activating protein 1
       1123 CHN1; chimerin 1
       1124 CHN2; chimerin 2
       393 ARHGAP4; Rho GTPase activating protein 4
       394 ARHGAP5; Rho GTPase activating protein 5
       395 ARHGAP6; Rho GTPase activating protein 6
       90627 STARD13; StAR related lipid transfer domain containing 13
       9754 STARD8; StAR related lipid transfer domain containing 8
       10395 DLC1; DLC1 Rho GTPase activating protein
       23779 ARHGAP8; Rho GTPase activating protein 8
       553158 PRR5-ARHGAP8; PRR5-ARHGAP8 readthrough
       64333 ARHGAP9; Rho GTPase activating protein 9
       79658 ARHGAP10; Rho GTPase activating protein 10
       89839 ARHGAP11B; Rho GTPase activating protein 11B
       9824 ARHGAP11A; Rho GTPase activating protein 11A
       201176 ARHGAP27; Rho GTPase activating protein 27
       94134 ARHGAP12; Rho GTPase activating protein 12
       23380 SRGAP2; SLIT-ROBO Rho GTPase activating protein 2
       57522 SRGAP1; SLIT-ROBO Rho GTPase activating protein 1
       9901 SRGAP3; SLIT-ROBO Rho GTPase activating protein 3
       55843 ARHGAP15; Rho GTPase activating protein 15
       55114 ARHGAP17; Rho GTPase activating protein 17
       93663 ARHGAP18; Rho GTPase activating protein 18
       343578 ARHGAP40; Rho GTPase activating protein 40
       79822 ARHGAP28; Rho GTPase activating protein 28
       84986 ARHGAP19; Rho GTPase activating protein 19
       57569 ARHGAP20; Rho GTPase activating protein 20
       57584 ARHGAP21; Rho GTPase activating protein 21
       57636 ARHGAP23; Rho GTPase activating protein 23
       58504 ARHGAP22; Rho GTPase activating protein 22
       83478 ARHGAP24; Rho GTPase activating protein 24
       9938 ARHGAP25; Rho GTPase activating protein 25
       23092 ARHGAP26; Rho GTPase activating protein 26
       23526 ARHGAP45; Rho GTPase activating protein 45
       9411 ARHGAP29; Rho GTPase activating protein 29
       257106 ARHGAP30; Rho GTPase activating protein 30
       57514 ARHGAP31; Rho GTPase activating protein 31
       9743 ARHGAP32; Rho GTPase activating protein 32
       115703 ARHGAP33; Rho GTPase activating protein 33
       2909 ARHGAP35; Rho GTPase activating protein 35
       158763 ARHGAP36; Rho GTPase activating protein 36
       80728 ARHGAP39; Rho GTPase activating protein 39
       4983 OPHN1; oligophrenin 1
       143872 ARHGAP42; Rho GTPase activating protein 42
       23616 SH3BP1; SH3 domain binding protein 1
       9912 ARHGAP44; Rho GTPase activating protein 44
       51291 GMIP; GEM interacting protein
       117289 TAGAP; T cell activation RhoGTPase activating protein
       85360 SYDE1; synapse defective Rho GTPase homolog 1
       84144 SYDE2; synapse defective Rho GTPase homolog 2
       116985 ARAP1; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
       116984 ARAP2; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
       64411 ARAP3; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
       29127 RACGAP1; Rac GTPase activating protein 1
       10928 RALBP1; ralA binding protein 1
       4649 MYO9A; myosin IXA
       4650 MYO9B; myosin IXB
       91544 UBXN11; UBX domain protein 11
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1] 
K20629 ABR; active breakpoint cluster region-related protein 
K18470 ARHGAP1; Rho GTPase-activating protein 1 
K20630 CHN1_2; chimaerin 
K20630 CHN1_2; chimaerin 
K20122 ARHGAP4; Rho GTPase-activating protein 4 
K13709 ARHGAP5; Rho GTPase-activating protein 5 
K20631 ARHGAP6; Rho GTPase-activating protein 6 
K20632 DLC; deleted in liver cancer protein 
K20632 DLC; deleted in liver cancer protein 
K20632 DLC; deleted in liver cancer protein 
K20633 ARHGAP8; Rho GTPase-activating protein 8 
K20633 ARHGAP8; Rho GTPase-activating protein 8 
K20634 ARHGAP9; Rho GTPase-activating protein 9 
K13736 ARHGAP10; Rho GTPase-activating protein 10 
K20635 ARHGAP11; Rho GTPase-activating protein 11 
K20635 ARHGAP11; Rho GTPase-activating protein 11 
K20636 ARHGAP12_27; Rho GTPase-activating protein 12/27 
K20636 ARHGAP12_27; Rho GTPase-activating protein 12/27 
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein 
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein 
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein 
K20637 ARHGAP15; Rho GTPase-activating protein 15 
K20638 ARHGAP17; Rho GTPase-activating protein 17 
K20639 ARHGAP18_28_40; Rho GTPase-activating protein 18/28/40 
K20639 ARHGAP18_28_40; Rho GTPase-activating protein 18/28/40 
K20639 ARHGAP18_28_40; Rho GTPase-activating protein 18/28/40 
K20640 ARHGAP19; Rho GTPase-activating protein 19 
K20641 ARHGAP20; Rho GTPase-activating protein 20 
K20315 ARHGAP21_23; Rho GTPase-activating protein 21/23 
K20315 ARHGAP21_23; Rho GTPase-activating protein 21/23 
K20642 ARHGAP22_24_25; Rho GTPase-activating protein 22/24/25 
K20642 ARHGAP22_24_25; Rho GTPase-activating protein 22/24/25 
K20642 ARHGAP22_24_25; Rho GTPase-activating protein 22/24/25 
K20071 ARHGAP26; Rho GTPase-activating protein 26 
K20644 ARHGAP29_45; Rho GTPase-activating protein 29/45 
K20644 ARHGAP29_45; Rho GTPase-activating protein 29/45 
K20645 ARHGAP30; Rho GTPase-activating protein 30 
K20646 ARHGAP31; Rho GTPase-activating protein 31 
K20647 ARHGAP32; Rho GTPase-activating protein 32 
K17933 ARHGAP33; Rho GTPase-activating protein 33 
K05732 ARHGAP35; glucocorticoid receptor DNA-binding factor 1 
K20648 ARHGAP36; Rho GTPase-activating protein 36 
K20649 ARHGAP39; Rho GTPase-activating protein 39 
K20650 OPHN1; oligophrenin-1 
K20651 ARHGAP42; Rho GTPase-activating protein 42 
K20652 SH3BP1; SH3-domain binding protein 1 
K21067 ARHGAP44; Rho GTPase-activating protein 44 
K20653 GMIP; GEM interacting protein 
K20654 TAGAP; T-cell activation Rho GTPase-activating protein 
K20655 SYDE; Rho GTPase-activating protein SYDE 
K20655 SYDE; Rho GTPase-activating protein SYDE 
K18439 ARAP1; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 
K18440 ARAP2; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 
K12490 ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 
K16733 RACGAP1; Rac GTPase-activating protein 1 
K08773 RALBP1; RalA-binding protein 1 
K10360 MYO9; myosin IX 
K10360 MYO9; myosin IX 
K24353 UBXN11; UBX domain-containing protein 11 
     Rho guanine nucleotide exchange factors (GEFs)

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Last updated: December 23, 2020