 09100 Metabolism
|
|
09120 Genetic Information Processing
|
|
 09130 Environmental Information Processing
|
|
09131 Membrane transport
|
|
09132 Signal transduction
|
02020 Two-component system [PATH:ko02020]
|
04010 MAPK signaling pathway [PATH:ko04010]
|
04013 MAPK signaling pathway - fly [PATH:ko04013]
|
04016 MAPK signaling pathway - plant [PATH:ko04016]
|
04011 MAPK signaling pathway - yeast [PATH:ko04011]
|
04012 ErbB signaling pathway [PATH:ko04012]
|
04014 Ras signaling pathway [PATH:ko04014]
|
04015 Rap1 signaling pathway [PATH:ko04015]
|
04310 Wnt signaling pathway [PATH:ko04310]
|
04330 Notch signaling pathway [PATH:ko04330]
|
04340 Hedgehog signaling pathway [PATH:ko04340]
|
04341 Hedgehog signaling pathway - fly [PATH:ko04341]
|
04350 TGF-beta signaling pathway [PATH:ko04350]
|
04390 Hippo signaling pathway [PATH:ko04390]
|
04391 Hippo signaling pathway - fly [PATH:ko04391]
|
04392 Hippo signaling pathway - multiple species [PATH:ko04392]
|
04370 VEGF signaling pathway [PATH:ko04370]
|
04371 Apelin signaling pathway [PATH:ko04371]
|
04630 JAK-STAT signaling pathway [PATH:ko04630]
|
04064 NF-kappa B signaling pathway [PATH:ko04064]
|
04668 TNF signaling pathway [PATH:ko04668]
|
 K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K09558 BAG4; BCL2-associated athanogene 4
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K05632 ITCH, AIP4; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K16510 RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K15637 PGAM5; serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K14625 CCL20; C-C motif chemokine 20
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K06052 JAG1, CD339; jagged-1
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05433 IL15; interleukin 15
K05419 LIF; leukemia inhibitory factor
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K09258 BCL3; B-cell CLL/lymphoma 3 protein
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K03172 TRAF1; TNF receptor-associated factor 1
K17072 IFI47; interferon gamma inducible protein 47
K09028 JUNB; transcription factor jun-B
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K07763 MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
K16366 EDN1; endothelin-1
K05449 VEGFC_D; vascular endothelial growth factor C/D
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K06494 SELE, CD62E; selectin, endothelial cell
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K03174 TRAF3; TNF receptor-associated factor 3
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K19901 DAB2IP, AIP1; disabled homolog 2-interacting protein
K09444 IRF1; interferon regulatory factor 1
K05415 IFNB; interferon beta
|
04066 HIF-1 signaling pathway [PATH:ko04066]
|
04068 FoxO signaling pathway [PATH:ko04068]
|
04020 Calcium signaling pathway [PATH:ko04020]
|
04070 Phosphatidylinositol signaling system [PATH:ko04070]
|
04072 Phospholipase D signaling pathway [PATH:ko04072]
|
04071 Sphingolipid signaling pathway [PATH:ko04071]
|
04024 cAMP signaling pathway [PATH:ko04024]
|
04022 cGMP-PKG signaling pathway [PATH:ko04022]
|
04151 PI3K-Akt signaling pathway [PATH:ko04151]
|
04152 AMPK signaling pathway [PATH:ko04152]
|
04150 mTOR signaling pathway [PATH:ko04150]
|
04075 Plant hormone signal transduction [PATH:ko04075]
|
|
09133 Signaling molecules and interaction
|
|
09140 Cellular Processes
|
|
09141 Transport and catabolism
|
|
09143 Cell growth and death
|
04110 Cell cycle [PATH:ko04110]
|
04111 Cell cycle - yeast [PATH:ko04111]
|
04112 Cell cycle - Caulobacter [PATH:ko04112]
|
04113 Meiosis - yeast [PATH:ko04113]
|
04114 Oocyte meiosis [PATH:ko04114]
|
04210 Apoptosis [PATH:ko04210]
|
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04396 CASP6; caspase 6 [EC:3.4.22.59]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10522 DIABLO, SMAC; diablo
K16943 SEPT4; septin 4
K08669 HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K07374 TUBA; tubulin alpha
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K05692 ACTB_G1; actin beta/gamma 1
K06114 SPTAN; spectrin alpha, non-erythrocytic (fodrin)
K12641 LMNA; lamin A/C
K07611 LMNB; lamin B
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K02310 DFFA, DFF45; DNA fragmentation factor, 45 kD, alpha subunit
K02311 DFFB, DFF40; DNA fragmentation factor, 40 kD, beta subunit [EC:3.-.-.-]
K01173 ENDOG; endonuclease G, mitochondrial
K04727 AIFM1, PDCD8; apoptosis-inducing factor 1 [EC:1.-.-.-]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K01275 CTSC; cathepsin C [EC:3.4.14.1]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K01373 CTSF; cathepsin F [EC:3.4.22.41]
K01366 CTSH; cathepsin H [EC:3.4.22.16]
K01371 CTSK; cathepsin K [EC:3.4.22.38]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01374 CTSO; cathepsin O [EC:3.4.22.42]
K01368 CTSS; cathepsin S [EC:3.4.22.27]
K01375 CTSL2, CTSV; cathepsin V [EC:3.4.22.43]
K08569 CTSW; cathepsin W [EC:3.4.22.-]
K08568 CTSZ; cathepsin X [EC:3.4.18.1]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K02308 DAXX; death-associated protein 6
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K19901 DAB2IP, AIP1; disabled homolog 2-interacting protein
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K04451 TP53, P53; tumor protein p53
K02512 HRK; activator of apoptosis harakiri
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02374 PTPN13, FAP-1; tyrosine-protein phosphatase non-receptor type 13
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K03172 TRAF1; TNF receptor-associated factor 1
K02162 BCL2A1; hematopoietic Bcl-2-related protein A1
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K10130 LRDD, PIDD; leucine-rich repeats and death domain-containing protein
K13773 TP53AIP1; p53-regulated apoptosis-inducing protein 1
K10132 BBC3, PUMA; Bcl-2-binding component 3
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K02186 CASP2; caspase 2 [EC:3.4.22.55]
K02582 NGFB; nerve growth factor, beta
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04736 IL3; interleukin 3
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
|
04214 Apoptosis - fly [PATH:ko04214]
|
04215 Apoptosis - multiple species [PATH:ko04215]
|
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3, PUMA; Bcl-2-binding component 3
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K10522 DIABLO, SMAC; diablo
K08669 HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
K16943 SEPT4; septin 4
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K16679 WGN; wengen
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K20009 DRONC; caspase Dronc [EC:3.4.22.-]
K20008 DCP1; death caspase-1 [EC:3.4.22.-]
K02561 BOK; Bcl-2-related ovarian killer protein
K20017 BUFFY; Bcl-2 family protein
K20018 GRIM; cell death protein Grim
K20014 RPR; cell death protein rpr
K20016 HID; cell death protein hid
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K20104 EGL1; programmed cell death activator egl-1 EGL-1
K20094 CED-9; cell death protein 9
K20105 CED-4; cell death protein 4
K20106 CED-3; cell death protein 3
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K08334 BECN, VPS30, ATG6; beclin
K10586 BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
K04489 CASP3A; caspase 3A [EC:3.4.22.-]
|
04216 Ferroptosis [PATH:ko04216]
|
04217 Necroptosis [PATH:ko04217]
|
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K10630 RBCK1, HOIL1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
K11974 RNF31, HOIP; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
K20894 SHARPIN; shank-associated RH domain-interacting protein
K17595 SPATA2; spermatogenesis-associated protein 2
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K00261 GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
K01915 glnA, GLUL; glutamine synthetase [EC:6.3.1.2]
K00688 PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K00522 FTH1; ferritin heavy chain [EC:1.16.3.1]
K13625 FTL; ferritin light chain
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K00460 ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K12350 SMPD1, ASM; sphingomyelin phosphodiesterase [EC:3.1.4.12]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K15637 PGAM5; serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K04519 IL1B; interleukin 1 beta
K12191 CHMP2A; charged multivesicular body protein 2A
K12192 CHMP2B; charged multivesicular body protein 2B
K12193 VPS24, CHMP3; charged multivesicular body protein 3
K12194 CHMP4A_B, SNF7, VPS32A_B; charged multivesicular body protein 4A/B
K24782 CHMP4C, SNF7, VPS32C; charged multivesicular body protein 4C
K12195 CHMP6, VPS20; charged multivesicular body protein 6
K12196 VPS4; vacuolar protein-sorting-associated protein 4
K12197 CHMP1, VPS46, DID2; charged multivesicular body protein 1
K12198 CHMP5, VPS60; charged multivesicular body protein 5
K15053 CHMP7; charged multivesicular body protein 7
K04982 TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K04383 IL1A; interleukin 1 alpha
K12967 IL33; interleukin 33
K10802 HMGB1; high mobility group protein B1
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04687 IFNG; interferon gamma
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K10160 TLR4, CD284; toll-like receptor 4
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K05842 TRIF; toll-like receptor adapter molecule 1
K05401 TLR3, CD283; toll-like receptor 3
K12965 ZBP1, DAI; Z-DNA binding protein 1
K21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]
K14381 SQSTM1; sequestosome 1
K04079 HSP90A, htpG; molecular chaperone HtpG
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K04727 AIFM1, PDCD8; apoptosis-inducing factor 1 [EC:1.-.-.-]
K11251 H2A; histone H2A
K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
K02161 BCL2; apoptosis regulator Bcl-2
|
04115 p53 signaling pathway [PATH:ko04115]
|
04218 Cellular senescence [PATH:ko04218]
|
|
09144 Cellular community - eukaryotes
|
|
09145 Cellular community - prokaryotes
|
|
09142 Cell motility
|
|
09150 Organismal Systems
|
|
09151 Immune system
|
04640 Hematopoietic cell lineage [PATH:ko04640]
|
04610 Complement and coagulation cascades [PATH:ko04610]
|
04611 Platelet activation [PATH:ko04611]
|
04613 Neutrophil extracellular trap formation [PATH:ko04613]
|
04620 Toll-like receptor signaling pathway [PATH:ko04620]
|
K05398 TLR1, CD281; toll-like receptor 1
K10159 TLR2, CD282; toll-like receptor 2
K10169 TLR6, CD286; toll-like receptor 6
K05399 LBP; lipopolysaccharide-binding protein
K04391 CD14; monocyte differentiation antigen CD14
K05400 LY96, MD-2; lymphocyte antigen 96
K05401 TLR3, CD283; toll-like receptor 3
K10160 TLR4, CD284; toll-like receptor 4
K10168 TLR5; toll-like receptor 5
K05404 TLR7; toll-like receptor 7
K10170 TLR8, CD288; toll-like receptor 8
K01371 CTSK; cathepsin K [EC:3.4.22.38]
K10161 TLR9, CD289; toll-like receptor 9
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05402 TOLLIP; toll-interacting protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K10030 IL8, CXCL8; interleukin 8
K12499 CCL5; C-C motif chemokine 5
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K05842 TRIF; toll-like receptor adapter molecule 1
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K09446 IRF5; interferon regulatory factor 5
K09447 IRF7; interferon regulatory factor 7
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K03174 TRAF3; TNF receptor-associated factor 3
K05411 IRF3; interferon regulatory factor 3
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K05416 CXCL9; C-X-C motif chemokine 9
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
|
04624 Toll and Imd signaling pathway [PATH:ko04624]
|
K20692 GNBP3; gram-negative bacteria-binding protein 3
K20697 GNBP1; gram-negative bacteria-binding protein 1
K01446 PGRP; peptidoglycan recognition protein
K20674 MODSP; modular serine protease [EC:3.4.21.-]
K20673 GRASS; gram-positive specific serine protease [EC:3.4.21.-]
K20693 SPHINX; sphinx [EC:3.4.21.-]
K20675 SPIRIT; serine protease immune response integrator
K20676 SPHEROIDE; spheroide [EC:3.4.21.-]
K20671 PSH; serine protease persephone [EC:3.4.21.-]
K20698 NEC; necrotic
K20672 SPE; spatzle-processing enzyme [EC:3.4.21.-]
K20694 SPZ; protein spaetzle
K18809 TL; protein toll
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K09254 REL; c-Rel proto-oncogene protein
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K20668 DEF; defensin
K20695 IM1_2_3; immune-induced peptide 1/2/3
K20702 IM4; immune-induced peptide 4
K20670 DRS; drosomycin
K20696 CEC; cecropin
K24097 PGRP-SD; peptidoglycan recognition protein SD
K24076 PGRP-LB; peptidoglycan-recognition protein LB [EC:3.5.1.28]
K24096 PGRP-SB; peptidoglycan recognition protein SB [EC:3.5.1.28]
K24092 PGRP-LA; peptidoglycan recognition protein LA
K24093 PGRP-LD; peptidoglycan recognition protein LD
K24074 PGRP-LE; peptidoglycan recognition protein LE
K24075 PGRP-LC; peptidoglycan recognition protein LC
K24077 PGRP-LF; peptidoglycan-recognition protein LF
K20701 PIRK; poor Imd response upon knock-in
K06689 UBE2D, UBC4, UBC5; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10580 UBE2N, BLU, UBC13; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K20699 IMD; immune deficiency
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04428 MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K13411 DUOX, THOX; dual oxidase [EC:1.6.3.1 1.11.1.-]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K09031 FOSLN; fos-like antigen, invertebrate
K20700 KEY; NF-kappa-B essential modulator
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K09255 ANK2, ANKB; ankyrin-2
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K20703 FAF1; FAS-associated factor 1
K20669 DPT; diptericin
|
04621 NOD-like receptor signaling pathway [PATH:ko04621]
|
K08727 NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04519 IL1B; interleukin 1 beta
K05482 IL18, IL1F4; interleukin 18
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K10030 IL8, CXCL8; interleukin 8
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K13916 CAMP, LL37; cathelicidin antimicrobial peptide
K05230 DEFA; defensin, alpha
K21100 DEFB4; beta-defensin 4
K23126 DEFB103; beta-defensin 103
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K17890 ATG16L1; autophagy-related protein 16-1
K08339 ATG5; autophagy-related protein 5
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
K10435 MAP1LC; microtubule-associated protein 1 light chain
K12795 SUGT1, SGT1; suppressor of G2 allele of SKP1
K20894 SHARPIN; shank-associated RH domain-interacting protein
K10630 RBCK1, HOIL1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
K11974 RNF31, HOIP; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K12797 CARD6; caspase recruitment domain-containing protein 6
K12792 TRIP6; thyroid receptor-interacting protein 6
K12796 ERBIN, ERBB2IP; erbb2-interacting protein
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K12794 CARD9; caspase recruitment domain-containing protein 9
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K12653 NLRX1; NLR family member X1
K08645 lef; anthrax lethal toxin endopeptidase [EC:3.4.24.83]
K11030 pagA; protective antigen
K20909 ANTXR; anthrax toxin receptor
K12798 NLRP1, CARD7; NACHT, LRR and PYD domains-containing protein 1
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K03443 PANX1; pannexin 1
K05220 P2RX7; P2X purinoceptor 7
K04977 TRPM2; transient receptor potential cation channel subfamily M member 2 [EC:3.6.1.13]
K04982 TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K04971 TRPV2; transient receptor potential cation channel subfamily V member 2
K04612 CASR; calcium-sensing receptor
K04622 GPRC6A; G protein-coupled receptor family C group 6 member A
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K01165 RNASEL; ribonuclease L
K17820 DHX33; ATP-dependent RNA helicase DHX33 [EC:5.6.2.6]
K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
K06030 MFN2, FZO1; mitofusin 2 [EC:3.6.5.-]
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
K03462 NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12]
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K20910 TXNIP; thioredoxin-interacting protein
K03671 TXN, trxA; thioredoxin
K20876 NEK7; serine/threonine-protein kinase Nek7 [EC:2.7.11.34]
K11864 BRCC3, BRCC36; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
K04079 HSP90A, htpG; molecular chaperone HtpG
K12801 CARD8, CARDINAL; caspase recruitment domain-containing protein 8
K15838 GPSM3, AGS4; G-protein signaling modulator 3
K14139 IRGM, LRG47; immunity-related GTPase family M protein [EC:3.6.5.-]
K12802 PYDC1; pyrin domain-containing protein 1
K20911 PYDC2, POP2; pyrin domain-containing protein 2
K12803 MEFV; pyrin
K12804 PSTPIP1; proline-serine-threonine phosphatase interacting protein 1
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02373 FADD; FAS-associated death domain protein
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K12806 CARD16_17_18; caspase recruitment domain-containing protein 16/17/18
K20863 NLRP6, NALP6; NACHT, LRR and PYD domains-containing protein 6
K20864 NLRP7, NALP7; NACHT, LRR and PYD domains-containing protein 7
K08598 yopJ; YopJ protease family
K20865 NLRP12; NACHT, LRR and PYD domains-containing protein 12
K02406 fliC, hag; flagellin
K12807 NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
K12805 NLRC4, CARD12; NLR family CARD domain-containing protein 4
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K20897 GBP2; guanylate-binding protein 2
K20898 GBP5; guanylate-binding protein 5
K12966 AIM2; absent in melanoma 2
K20914 IFI16; gamma-interferon-inducible protein 16
K20915 TP53BP1, P202; tumor suppressor p53-binding protein 1
K20916 POP3; pyrin domain-only protein 3
K04513 RHOA; Ras homolog gene family, member A
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K06630 YWHAE; 14-3-3 protein epsilon
K20899 GBP1_3_4_7; guanylate-binding protein 1/3/4/7
K04395 CASP5; caspase 5 [EC:3.4.22.58]
K04394 CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
K20917 GSDMD; gasdermin-D
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K10160 TLR4, CD284; toll-like receptor 4
K05842 TRIF; toll-like receptor adapter molecule 1
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
|
04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
|
K12646 RIGI, DDX58; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:5.6.2.6]
K27391 ZNFX1; NFX1-type zinc finger-containing protein 1
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K12649 DHX58, LGP2; ATP-dependent RNA helicase DHX58 [EC:5.6.2.6]
K03174 TRAF3; TNF receptor-associated factor 3
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K12651 AZI2; 5-azacytidine-induced protein 2
K12652 TBKBP1; TANK-binding kinase 1-binding protein
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05440 IFNW; interferon omega
K05442 IFNE; interferon epsilon
K05441 IFNK; interferon kappa
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K10030 IL8, CXCL8; interleukin 8
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12968 ADAR, ADAR1; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
K10652 TRIM25, EFP; tripartite motif-containing protein 25 [EC:2.3.2.27]
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]
K12159 ISG15; ubiquitin cross-reactive protein
K08339 ATG5; autophagy-related protein 5
K08336 ATG12; ubiquitin-like protein ATG12
K12653 NLRX1; NLR family member X1
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K12655 OTUD5, DUBA; OTU domain-containing protein 5 [EC:3.4.19.12]
K12656 SIKE; suppressor of IKK-epsilon
K11594 DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
K00863 DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]
|
04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
|
K03018 RPC1, POLR3A; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]
K03021 RPC2, POLR3B; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]
K03023 RPC3, POLR3C; DNA-directed RNA polymerase III subunit RPC3
K03026 RPC4, POLR3D; DNA-directed RNA polymerase III subunit RPC4
K14721 RPC5, POLR3E; DNA-directed RNA polymerase III subunit RPC5
K03027 RPAC1, RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1
K03019 RPC11, POLR3K; DNA-directed RNA polymerase III subunit RPC11
K03020 RPAC2, RPC19, POLR1D; DNA-directed RNA polymerases I and III subunit RPAC2
K03022 RPC8, POLR3H; DNA-directed RNA polymerase III subunit RPC8
K03024 RPC7, POLR3G; DNA-directed RNA polymerase III subunit RPC7
K03025 RPC6, POLR3F; DNA-directed RNA polymerase III subunit RPC6
K03013 RPABC1, RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
K03014 RPABC2, RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
K03016 RPABC3, RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
K03009 RPABC4, RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
K03007 RPABC5, RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
K12646 RIGI, DDX58; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05405 IL6; interleukin 6
K12889 PCBP1; poly(rC)-binding protein 1
K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
K27162 ZCCHC3; zinc finger CCHC domain-containing protein 3
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K20027 ZDHHC1_11; palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225]
K13116 DDX41, ABS; ATP-dependent RNA helicase DDX41 [EC:5.6.2.7]
K20914 IFI16; gamma-interferon-inducible protein 16
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K12965 ZBP1, DAI; Z-DNA binding protein 1
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K12964 CCL4; C-C motif chemokine 4
K12499 CCL5; C-C motif chemokine 5
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12966 AIM2; absent in melanoma 2
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K12803 MEFV; pyrin
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K22146 GSDME, DFNA5; gasdermin-E
K20917 GSDMD; gasdermin-D
K04519 IL1B; interleukin 1 beta
K05482 IL18, IL1F4; interleukin 18
K12967 IL33; interleukin 33
K12968 ADAR, ADAR1; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
K01158 DNASE2; deoxyribonuclease II [EC:3.1.22.1]
K12969 E3L; Poxviridae RNA-binding protein E3
K12970 M45; Murid betaherpesvirus 1 ribonucleoside-diphosphate reductase [EC:1.17.4.1]
K12971 IFI202; interferon-activable protein 202
|
04625 C-type lectin receptor signaling pathway [PATH:ko04625]
|
04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
|
04612 Antigen processing and presentation [PATH:ko04612]
|
04660 T cell receptor signaling pathway [PATH:ko04660]
|
04658 Th1 and Th2 cell differentiation [PATH:ko04658]
|
04659 Th17 cell differentiation [PATH:ko04659]
|
04657 IL-17 signaling pathway [PATH:ko04657]
|
K05493 IL17E, IL25; interleukin 17E
K05164 IL17RA, CD217; interleukin 17 receptor A
K05165 IL17RB, IL17RH1; interleukin 17 receptor B
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K21124 TRAF3IP2, ACT1; adaptor protein CIKS
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04379 FOS; proto-oncogene protein c-fos
K09029 FOSB; protein FosB
K04448 JUN; transcription factor AP-1
K04449 JUND; transcription factor jun-D
K04502 FOSL1; fos-like antigen 1
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05435 IL13; interleukin 13
K21083 CCL17; C-C motif chemokine 17
K16597 CCL11; C-C motif chemokine 11
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05166 IL17RC, IL17RL; interleukin 17 receptor C
K03174 TRAF3; TNF receptor-associated factor 3
K03352 APC5, ANAPC5; anaphase-promoting complex subunit 5
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06855 MAPK4_6; mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K09848 TRAF4; TNF receptor-associated factor 4
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
K09849 TRAF5; TNF receptor-associated factor 5
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K12890 SRSF1, SFRS1, ASF, SF2; serine/arginine-rich splicing factor 1
K13088 ELAVL1, HUR; ELAV-like protein 1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K14624 CCL2, MCP1; C-C motif chemokine 2
K05509 CCL7; C-C motif chemokine 7
K14625 CCL20; C-C motif chemokine 20
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K21100 DEFB4; beta-defensin 4
K13908 MUC5; mucin-5
K21126 S100A7; protein S100-A7
K21127 S100A8; protein S100-A8
K21128 S100A9; protein S100-A9
K21129 LCN2; lipocalin 2
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
K05491 IL17C, CX2; interleukin 17C
K05168 IL17RE; interleukin 17 receptor E
K04519 IL1B; interleukin 1 beta
K04687 IFNG; interferon gamma
K05490 IL17B, CX1; interleukin 17B
K05492 IL17D, IL27; interleukin 17D
|
04662 B cell receptor signaling pathway [PATH:ko04662]
|
04664 Fc epsilon RI signaling pathway [PATH:ko04664]
|
04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
|
04670 Leukocyte transendothelial migration [PATH:ko04670]
|
04672 Intestinal immune network for IgA production [PATH:ko04672]
|
04062 Chemokine signaling pathway [PATH:ko04062]
|
|
09152 Endocrine system
|
|
09153 Circulatory system
|
|
09154 Digestive system
|
|
09155 Excretory system
|
|
09156 Nervous system
|
|
09157 Sensory system
|
|
09158 Development and regeneration
|
|
09149 Aging
|
|
09159 Environmental adaptation
|
|
09160 Human Diseases
|
|
09161 Cancer: overview
|
05200 Pathways in cancer [PATH:ko05200]
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1, DIP13A; DCC-interacting protein 13 alpha
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT, SERPINA8; angiotensinogen
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04236 F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06485 ITGA6, CD49f; integrin alpha 6
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K08878 BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG, BK; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05071 IL4R, CD124; interleukin 4 receptor
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05072 IL7R, CD127; interleukin 7 receptor
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1, pnt; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8, CXCL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6, PTC; coiled-coil domain-containing protein 6
K09289 NCOA4, PTC3; nuclear receptor coactivator 4
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR, MLP1, MLP2; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K04411 STK4, MST1; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K08528 RARB, NR1B2; retinoic acid receptor beta
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K09101 NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K10056 JUP, PG; junction plakoglobin
K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K08527 RARA, NR1B1; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 RUNX1, AML1; runt-related transcription factor 1
K10053 RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03347 CUL1, CDC53; cullin 1
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3, PUMA; Bcl-2-binding component 3
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC, TCEB1; elongin-C
K03873 ELOB, TCEB2; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1, CD339; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR, NR3C4; androgen receptor
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K01351 KLK3, PSA; semenogelase [EC:3.4.21.77]
|
05202 Transcriptional misregulation in cancer [PATH:ko05202]
|
05206 MicroRNAs in cancer [PATH:ko05206]
|
05205 Proteoglycans in cancer [PATH:ko05205]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
|
05203 Viral carcinogenesis [PATH:ko05203]
|
05230 Central carbon metabolism in cancer [PATH:ko05230]
|
05231 Choline metabolism in cancer [PATH:ko05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
|
|
09162 Cancer: specific types
|
|
09172 Infectious disease: viral
|
05166 Human T-cell leukemia virus 1 infection [PATH:ko05166]
|
05170 Human immunodeficiency virus 1 infection [PATH:ko05170]
|
K24266 gp120; HIV envelope glycoprotein gp120
K06454 CD4; T-cell surface glycoprotein CD4
K22890 vpu; HIV-1 protein Vpu
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03347 CUL1, CDC53; cullin 1
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K22891 nef; HIV protein Nef
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05760 PXN; paxillin
K04438 CRK, CRKII; C-crk adapter molecule crk
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K02158 BAD; Bcl-2-antagonist of cell death
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05765 CFL; cofilin
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K19258 tat; HIV protein Tat
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K22892 vif; HIV virion infectivity factor
K22202 vpr; HIV virus protein R
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
K10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]
K06731 BST2, CD317; bone marrow stromal cell antigen 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K09849 TRAF5; TNF receptor-associated factor 5
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K12392 AP1B1; AP-1 complex subunit beta-1
K12391 AP1G1; AP-1 complex subunit gamma-1
K12393 AP1M; AP-1 complex subunit mu
K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
K12395 AP1S3; AP-1 complex subunit sigma-3
K08055 B2M; beta-2-microglobulin
K03873 ELOB, TCEB2; elongin-B
K03872 ELOC, TCEB1; elongin-C
K10612 CUL5; cullin 5
K10611 RBX2, ROC2, RNF7; RING-box protein 2
K11789 DCAF1, VPRBP; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
K10610 DDB1; DNA damage-binding protein 1
K10609 CUL4; cullin 4
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
|
05161 Hepatitis B [PATH:ko05161]
|
K23128 S; Orthohepadnavirus large envelope protein
K06255 HSPG2; basement membrane-specific heparan sulfate proteoglycan core protein
K14341 SLC10A1, NTCP; solute carrier family 10 (sodium/bile acid cotransporter), member 1
K21854 X; Orthohepadnavirus protein X
K23129 C; Orthohepadnavirus capsid protein
K21037 P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H [EC:2.7.7.7 2.7.7.49 3.1.26.4]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K23605 SMAD3; mothers against decapentaplegic homolog 3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K10610 DDB1; DNA damage-binding protein 1
K10140 DDB2; DNA damage-binding protein 2
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K02161 BCL2; apoptosis regulator Bcl-2
K02158 BAD; Bcl-2-antagonist of cell death
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K02084 APAF1; apoptotic protease-activating factor
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04451 TP53, P53; tumor protein p53
K06627 CCNA; cyclin-A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K03662 ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K15041 VDAC3; voltage-dependent anion channel protein 3
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04448 JUN; transcription factor AP-1
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K10030 IL8, CXCL8; interleukin 8
K04802 PCNA; proliferating cell nuclear antigen
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04375 ELK1; ETS domain-containing protein Elk-1
K10159 TLR2, CD282; toll-like receptor 2
K04729 MYD88; myeloid differentiation primary response protein MyD88
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K10160 TLR4, CD284; toll-like receptor 4
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K05405 IL6; interleukin 6
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K05401 TLR3, CD283; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K12646 RIGI, DDX58; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:5.6.2.6]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K11594 DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
|
05160 Hepatitis C [PATH:ko05160]
|
K12473 LDLR; low-density lipoprotein receptor
K22272 E2; Hepatitis C virus envelope glycoprotein E2
K13885 SCARB1; scavenger receptor class B, member 1
K06508 CD81, TAPA1, TSPAN28; CD81 antigen
K06087 CLDN; claudin
K06088 OCLN; occludin
K24861 E1; Hepatitis C virus envelope glycoprotein E1
K22497 NS2; Hepatitis C virus non-structural protein 2 [EC:3.4.22.-]
K22273 NS3; Hepatitis C virus serine protease / helicase NS3 [EC:3.4.21.98 3.6.1.15 5.6.2.6]
K22274 NS4A; Hepatitis C virus non-structural protein 4A
K22498 NS4B; Hepatitis C virus non-structural protein 4B
K22275 NS5A; Hepatitis C virus non-structural protein 5A
K22472 NS5B; Hepatitis C virus RNA-dependent RNA polymerase [EC:2.7.7.48]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K01165 RNASEL; ribonuclease L
K12646 RIGI, DDX58; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04687 IFNG; interferon gamma
K05401 TLR3, CD283; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K22271 Core; Hepatitis C virus core protein
K14217 IFIT1; interferon-induced protein with tetratricopeptide repeats 1
K03250 EIF3E, INT6; translation initiation factor 3 subunit E
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04692 STAT3; signal transducer and activator of transcription 3
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K14754 MX; interferon-induced GTP-binding protein Mx
K15045 RSAD2; radical S-adenosyl methionine domain-containing protein 2
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02158 BAD; Bcl-2-antagonist of cell death
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04451 TP53, P53; tumor protein p53
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K06698 PSME3; proteasome activator subunit 3 (PA28 gamma)
K08524 RXRA, NR2B1; retinoid X receptor alpha
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K08536 NR1H3, LXRA; liver X receptor alpha
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
|
05171 Coronavirus disease - COVID-19 [PATH:ko05171]
|
05164 Influenza A [PATH:ko05164]
|
K19251 HA; Influenza A virus hemagglutinin
K19392 NA; Influenza A/B virus neuraminidase [EC:3.2.1.18]
K19394 M2; Influenza A virus matrix protein 2
K19393 M1; Influenza A/B virus matrix protein 1
K19391 NP; Influenza virus nucleoprotein
K19390 PA; Influenza virus polymerase acidic protein
K19389 PB1; Influenza virus RNA-directed RNA polymerase catalytic subunit [EC:2.7.7.48]
K19388 PB2; Influenza virus polymerase basic protein 2
K19396 NS1; Influenza A virus non-structural protein 1
K19397 PB1F2; Influenza A virus protein PB1-F2
K19395 NEP, NS2; Influenza A virus nuclear export protein
K01340 E3.4.21.59; tryptase [EC:3.4.21.59]
K01315 PLG; plasminogen [EC:3.4.21.7]
K01312 PRSS1_2_3; trypsin [EC:3.4.21.4]
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09635 TMPRSS4; transmembrane protease serine 4 [EC:3.4.21.-]
K09641 TMPRSS11D; transmembrane protease serine 11D [EC:3.4.21.-]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K01165 RNASEL; ribonuclease L
K09507 DNAJB1; DnaJ homolog subfamily B member 1
K09523 DNAJC3; DnaJ homolog subfamily C member 3
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K10652 TRIM25, EFP; tripartite motif-containing protein 25 [EC:2.3.2.27]
K12646 RIGI, DDX58; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:5.6.2.6]
K12653 NLRX1; NLR family member X1
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K21348 CALCOCO2, NDP52; calcium-binding and coiled-coil domain-containing protein 2
K05401 TLR3, CD283; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K10160 TLR4, CD284; toll-like receptor 4
K05404 TLR7; toll-like receptor 7
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K09447 IRF7; interferon regulatory factor 7
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K10030 IL8, CXCL8; interleukin 8
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K14754 MX; interferon-induced GTP-binding protein Mx
K12968 ADAR, ADAR1; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K06752 MHC2; MHC class II antigen
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05482 IL18, IL1F4; interleukin 18
K12967 IL33; interleukin 33
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K05862 VDAC1; voltage-dependent anion channel protein 1
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K14404 CPSF4, YTH1; cleavage and polyadenylation specificity factor subunit 4
K14396 PABPN1, PABP2; polyadenylate-binding protein 2
K14284 NXF, TAP, MEX67; nuclear RNA export factor
K14285 NXT1_2, P15; NTF2-related export protein 1/2
K15047 HNRNPUL1, E1BAP5; heterogeneous nuclear ribonucleoprotein U-like protein 1
K14298 RAE1, GLE2; mRNA export factor
K14297 NUP98, ADAR2, NUP116; nuclear pore complex protein Nup98-Nup96
K15045 RSAD2; radical S-adenosyl methionine domain-containing protein 2
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K05692 ACTB_G1; actin beta/gamma 1
K07904 RAB11A; Ras-related protein Rab-11A
K07905 RAB11B; Ras-related protein Rab-11B
K14290 XPO1, CRM1; exportin-1
K23940 KPNA1; importin subunit alpha-5
K15043 KPNA2_7; importin subunit alpha-1/8
K15042 KPNA5_6; importin subunit alpha-6/7
|
05162 Measles [PATH:ko05162]
|
K19378 H; Morbillivirus hemagglutinin glycoprotein
K04007 CD46, MCP; membrane cofactor protein
K05763 MSN; moesin
K06536 SLAMF1, CD150; signaling lymphocytic activation molecule family member 1
K19379 F; Morbillivirus fusion glycoprotein F0
K06563 CLEC4L_M, DC-SIGN, CD209, CD299; C-type lectin domain family 4 member L/M
K12646 RIGI, DDX58; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:5.6.2.6]
K22281 V; measles non-structural protein V
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K19380 N; Morbillivirus nucleoprotein
K22280 C; measles protein C
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K19377 P, P/V/C; Morbillivirus phosphoprotein
K05404 TLR7; toll-like receptor 7
K10161 TLR9, CD289; toll-like receptor 9
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K12968 ADAR, ADAR1; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
K14754 MX; interferon-induced GTP-binding protein Mx
K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K19381 M; Morbillivirus matrix protein
K19376 L; Morbillivirus RNA-directed RNA polymerase L [EC:2.7.7.48 3.6.1.- 2.7.7.88 2.1.1.375]
K07899 RAB9A, RAB9; Ras-related protein Rab-9A
K07900 RAB9B; Ras-related protein Rab-9B
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03247 EIF3H; translation initiation factor 3 subunit H
K03237 EIF2S1; translation initiation factor 2 subunit 1
K10144 RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K10148 TP73; tumor protein p73
K10132 BBC3, PUMA; Bcl-2-binding component 3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02158 BAD; Bcl-2-antagonist of cell death
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06626 CCNE; G1/S-specific cyclin-E1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06470 CD28; CD28 antigen
K05429 IL2; interleukin 2
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K12560 FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
|
05168 Herpes simplex virus 1 infection [PATH:ko05168]
|
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K05152 TNFRSF14, HVEM, CD270; tumor necrosis factor receptor superfamily member 14
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K14624 CCL2, MCP1; C-C motif chemokine 2
K19264 gD; Simplexvirus envelope glycoprotein D
K06081 NECTIN1, PVRL1, CD111; poliovirus receptor-related protein 1
K06531 PVRL2, CD112; poliovirus receptor-related protein 2
K19255 gB; Herpesviridae envelope glycoprotein B
K19256 gC; Simplexvirus envelope glycoprotein C
K15411 PILR; paired immunoglobulin-like type 2 receptor
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K19434 gH, UL22; Simplexvirus envelope glycoprotein H
K19435 gL, UL1; Simplexvirus envelope glycoprotein L
K06484 ITGA5, CD49e; integrin alpha 5
K06493 ITGB3, CD61; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K12794 CARD9; caspase recruitment domain-containing protein 9
K05411 IRF3; interferon regulatory factor 3
K05415 IFNB; interferon beta
K19436 ICP0, RL2; Simplexvirus E3 ubiquitin-protein ligase ICP0
K04451 TP53, P53; tumor protein p53
K03990 C3; complement component 3
K03994 C5; complement component 5
K15412 CFP; complement factor properdin
K10159 TLR2, CD282; toll-like receptor 2
K10161 TLR9, CD289; toll-like receptor 9
K04729 MYD88; myeloid differentiation primary response protein MyD88
K09447 IRF7; interferon regulatory factor 7
K05401 TLR3, CD283; toll-like receptor 3
K19439 US3; Simplexvirus serine/threonine-protein kinase US3 [EC:2.7.11.1]
K05842 TRIF; toll-like receptor adapter molecule 1
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04519 IL1B; interleukin 1 beta
K12499 CCL5; C-C motif chemokine 5
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K19438 US11; Simplexvirus RNA-binding protein
K12646 RIGI, DDX58; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:5.6.2.6]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K21075 UL36, UL48; Herpesviridae large tegument protein deneddylase [EC:3.4.19.12 3.4.22.-]
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K19437 RL1; Simplexvirus neurovirulence factor ICP34.5
K05414 IFNA; interferon alpha
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K19447 UL41; Simplexvirus virion host shutoff protein [EC:3.1.27.-]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K03239 EIF2B1; translation initiation factor eIF-2B subunit alpha
K03754 EIF2B2; translation initiation factor eIF-2B subunit beta
K03241 EIF2B3; translation initiation factor eIF-2B subunit gamma
K03680 EIF2B4; translation initiation factor eIF-2B subunit delta
K03240 EIF2B5; translation initiation factor eIF-2B subunit epsilon
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K01165 RNASEL; ribonuclease L
K19444 UL48; Simplexvirus tegument protein VP16
K14966 HCFC1; host cell factor 1
K27390 HCFC2; host cell factor 2
K09364 POU2F, OTF; POU domain transcription factor, class 2
K19445 ICP4, RS1; Simplexvirus major viral transcription factor ICP4
K19441 US1; Simplexvirus transcriptional regulator ICP22
K19443 UL54; Simplexvirus mRNA export factor
K19446 US12; Simplexvirus ICP47 protein
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K19440 UL13; Simplexvirus serine/threonine-protein kinase UL13 [EC:2.7.11.1]
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K09228 KRAB; KRAB domain-containing zinc finger protein
K06731 BST2, CD317; bone marrow stromal cell antigen 2
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K02308 DAXX; death-associated protein 6
K15413 SP100; nuclear body protein Sp100
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K06752 MHC2; MHC class II antigen
K06505 CD74, DHLAG; CD74 antigen
K23212 UL46; Simplexvirus tegument protein VP11/12
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K15409 SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]
K12890 SRSF1, SFRS1, ASF, SF2; serine/arginine-rich splicing factor 1
K12891 SRSF2_8, SFRS2A_B; serine/arginine-rich splicing factor 2/8
K12892 SRSF3, SFRS3; serine/arginine-rich splicing factor 3
K12893 SRSF4_5_6, SFRS4_5_6; serine/arginine-rich splicing factor 4/5/6
K12896 SRSF7, SFRS7; serine/arginine-rich splicing factor 7
K21123 SRSF9, SFRS9; serine/arginine-rich splicing factor 9
K14284 NXF, TAP, MEX67; nuclear RNA export factor
K12881 THOC4, ALY; THO complex subunit 4
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K19448 UL39; Simplexvirus ribonucleoside-diphosphate reductase large subunit [EC:1.17.4.1]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K02158 BAD; Bcl-2-antagonist of cell death
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
|
05163 Human cytomegalovirus infection [PATH:ko05163]
|
K22773 gB, UL55; Betaherpesvirinae envelope glycoprotein B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K22774 UL123; HCMV immediate-early protein 1
K22775 UL122; Cytomegalovirus viral transcription factor IE2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K22776 UL38; Cytomegalovirus apoptosis inhibitor UL38
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04684 SP1; transcription factor Sp1
K22777 gH, UL75; Cytomegalovirus envelope glycoprotein H
K22778 gL, UL115; Cytomegalovirus envelope glycoprotein L
K06487 ITGAV, CD51; integrin alpha V
K06493 ITGB3, CD61; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K22779 UL82; Cytomegalovirus tegument protein pp71
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K09849 TRAF5; TNF receptor-associated factor 5
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K22780 UL26; Cytomegalovirus tegument protein UL26
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K10030 IL8, CXCL8; interleukin 8
K05405 IL6; interleukin 6
K22781 US28; HCMV envelope protein US28
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K16529 ARHGEF13; A-kinase anchor protein 13
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K02105 CTNNB1; catenin beta 1
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
K05055 IL6R, CD126; interleukin 6 receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05448 VEGFA; vascular endothelial growth factor A
K22782 UL33; Cytomegalovirus G-protein coupled receptor UL33
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K22783 US27; HCMV envelope glycoprotein US27
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K05760 PXN; paxillin
K21533 vIL10; Herpesviridae/Poxviridae viral interleukin 10
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K21046 UL146; HCMV chemokine vCXCL1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K22784 UL22A; HCMV glycoprotein UL22A
K04176 CCR1, CD191; C-C chemokine receptor type 1
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04180 CCR5, CD195; C-C chemokine receptor type 5
K22785 US6; HCMV membrane glycoprotein US6
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K21050 US2; HCMV unique short US2 glycoprotein
K22786 US11; HCMV membrane glycoprotein US11
K22787 US3; HCMV membrane glycoprotein US3
K21051 US10; HCMV unique short US10 glycoprotein
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K22788 UL36; Cytomegalovirus viral inhibitor of caspase-8-induced apoptosis
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K22789 UL37; UL37 HCMV immediate early glycoprotein
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
|
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:ko05167]
|
K21649 ORF4; KSHV complement control protein
K03990 C3; complement component 3
K05401 TLR3, CD283; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09447 IRF7; interferon regulatory factor 7
K21650 KIE1, ORF50; KSHV transcription activator ORF50
K21859 KIE2, ORF45; KSHV transcription activator ORF45
K21652 vIRF3; KSHV interferon regulatory factor-like protein 3
K05414 IFNA; interferon alpha
K05411 IRF3; interferon regulatory factor 3
K21653 vIRF1, K9; KSHV interferon regulatory factor-like protein 1
K21654 vIRF2, K11; KSHV interferon regulatory factor-like protein 2
K21655 K8; KSHV E3 SUMO-protein ligase K-bZIP
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K21656 K12; KSHV protein K12
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K15308 TTP; tristetraprolin
K05405 IL6; interleukin 6
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K21657 K4; KSHV macrophage inflammatory protein 2
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04176 CCR1, CD191; C-C chemokine receptor type 1
K21658 K4.1; KSHV protein vCCL3
K04179 CCR4, CD194; C-C chemokine receptor type 4
K21659 K6; KSHV protein K6
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K21660 vBCL2, ORF16; KSHV apoptosis regulator BCL2 homolog
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K21661 vIAP, K7; KSHV inhibitor of apoptosis protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K21662 vFLIP, K13, ORF71; KSHV FLICE inhibitory protein
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K21651 K15; KSHV signal transducing membrane protein
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K21663 vCyclin, ORF72; KSHV cyclin homolog
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K21664 vLANA, ORF73; KSHV latency-associated nuclear antigen
K06751 MHC1; MHC class I antigen
K21665 MIR1, K3; KSHV E3 ubiquitin-protein ligase MIR1 [EC:2.3.2.36]
K21666 MIR2, K5; KSHV E3 ubiquitin-protein ligase MIR2 [EC:2.3.2.36]
K05132 IFNGR1, CD119; interferon gamma receptor 1
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K05413 CD86; CD86 antigen
K07985 MIC; MHC class I-related protein
K10071 CLEC2B; C-type lectin domain family 2 member B
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K08334 BECN, VPS30, ATG6; beclin
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
K10435 MAP1LC; microtubule-associated protein 1 light chain
K21667 vGPCR; KSHV G-protein coupled receptor
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K12365 PREX1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K21860 K14; KSHV OX-2 membrane glycoprotein
K21668 CD200R; cell surface glycoprotein CD200 receptor
K21669 K1; KSHV protein K1
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K10030 IL8, CXCL8; interleukin 8
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K17901 RCAN1, MCIP1; calcipressin-1
K18497 FGF2; fibroblast growth factor 2
K05448 VEGFA; vascular endothelial growth factor A
K17386 PDGFB; platelet-derived growth factor subunit B
K21670 vIL6, K2; KSHV interleukin 6
K05466 ANGPT2; angiopoietin 2
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
|
05169 Epstein-Barr virus infection [PATH:ko05169]
|
K19450 BLLF1; Lymphocryptovirus envelope glycoprotein GP350
K04012 CR2, CD21; complement receptor type 2
K06465 CD19; B-lymphocyte antigen CD19
K19451 gH; Lymphocryptovirus envelope glycoprotein H
K19452 gL; Lymphocryptovirus envelope glycoprotein L
K19453 BBRF2; Lymphocryptovirus virion egress protein UL7
K06752 MHC2; MHC class II antigen
K10159 TLR2, CD282; toll-like receptor 2
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K22972 BPLF1; Lymphocryptovirus large tegment protein deneddylase [EC:3.4.19.12]
K12646 RIGI, DDX58; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K09447 IRF7; interferon regulatory factor 7
K19455 BGLF4; Lymphocryptovirus serine/threonine-protein kinase BGLF4 [EC:2.7.11.1]
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K19460 LMP2A; Lymphocryptovirus latent membrane protein 2A
K23074 LMP2B; Lymphocryptovirus latent membrane protein 2B
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K19459 LMP1; Lymphocryptovirus latent membrane protein 1
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12159 ISG15; ubiquitin cross-reactive protein
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K19458 EBNA6, EBNA3C; Lymphocryptovirus nuclear antigen 6
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K22973 BARF1; Lymphocryptovirus secreted protein BARF1
K02161 BCL2; apoptosis regulator Bcl-2
K19463 BHRF1; Lymphocryptovirus apoptosis regulator BHRF1
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K19461 EBNA1, BKRF1; Lymphocryptovirus nuclear antigen 1
K22974 BNLF2A; Lymphocryptovirus protein BNLF2a
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K22975 BILF1; Lymphocryptovirus G-protein coupled receptor BILF1
K19456 EBNALP; Lymphocryptovirus nuclear antigen leader protein
K19457 EBNA2; Lymphocryptovirus nuclear antigen 2
K06063 SNW1, SKIIP, SKIP; SNW domain-containing protein 1
K11644 SIN3A; paired amphipathic helix protein Sin3a
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06065 NCOR2, SMRT; nuclear receptor co-repressor 2
K19202 SAP30; histone deacetylase complex subunit SAP30
K06066 CIR; CBF1 interacting corepressor
K21855 EBNA3, EBNA3A; Lymphocryptovirus nuclear antigen 3
K21856 EBNA4, EBNA3B; Lymphocryptovirus nuclear antigen 4
K06053 RBPSUH, RBPJK; recombining binding protein suppressor of hairless
K06054 HES1; hairy and enhancer of split 1
K06468 FCER2, CD23; low affinity immunoglobulin epsilon Fc receptor
K09279 RUNX3, AML2; runt-related transcription factor 3
K04377 MYC; Myc proto-oncogene protein
K11838 USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K19462 BZLF1; Lymphocryptovirus trans-activator protein BZLF1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K09849 TRAF5; TNF receptor-associated factor 5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K01510 ENTPD1_3_8, CD39; apyrase [EC:3.6.1.5]
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K06256 CD44; CD44 antigen
K05718 ITGAL, CD11a; integrin alpha L
K06492 CD58, LFA3; CD58 antigen
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K07606 VIM; vimentin
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K10591 NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K07371 BLNK; B-cell linker protein
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06627 CCNA; cyclin-A
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
|
05165 Human papillomavirus infection [PATH:ko05165]
|
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K21807 E6; Alphapapillomavirus protein E6
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K10587 UBE3A, E6AP; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
K05401 TLR3, CD283; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K05415 IFNB; interferon beta
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K11315 TADA3, ADA3, NGG1; transcriptional adapter 3
K04451 TP53, P53; tumor protein p53
K19260 L1; Papillomaviridae major capsid protein L1
K21808 L2; Alphapapillomavirus minor capsid protein L2
K05631 AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04393 CDC42; cell division control protein 42
K16175 SCRIB; protein scribble
K12076 DLG1; disks large protein 1
K12075 DLG2; discs large protein 2
K21098 DLG3; discs large protein 3
K06094 LLGL; lethal(2) giant larvae protein
K06090 CRB3; crumbs 3
K06092 INADL, PATJ; InaD-like protein
K06091 MPP5, PALS1; MAGUK p55 subfamily member 5
K03900 VWF; von Willebrand factor
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K06493 ITGB3, CD61; integrin beta 3
K06525 ITGB4, CD104; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05760 PXN; paxillin
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K13365 SLC9A3R1, NHERF1; sodium/hydrogen exchange regulatory cofactor NHE-RF1
K21809 E7; Alphapapillomavirus protein E7
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K21810 E1; Alphapapillomavirus replication protein E1 [EC:5.6.2.-]
K21811 E2; Alphapapillomavirus regulatory protein E2
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K02158 BAD; Bcl-2-antagonist of cell death
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K21812 E5; Alphapapillomavirus protein E5
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K17454 E2F1; transcription factor E2F1
K06627 CCNA; cyclin-A
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K05448 VEGFA; vascular endothelial growth factor A
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K12236 NFX1; transcriptional repressor NF-X1
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11643 CHD4, MI2B; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-]
K09444 IRF1; interferon regulatory factor 1
K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
K06751 MHC1; MHC class I antigen
K14009 BCAP31, BAP31; B-cell receptor-associated protein 31
K02145 ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:7.1.2.2]
K02147 ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
K02148 ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C
K02149 ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D
K02150 ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
K02151 ATPeV1F, ATP6S14; V-type H+-transporting ATPase subunit F
K02152 ATPeV1G, ATP6G; V-type H+-transporting ATPase subunit G
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K02154 ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
K02146 ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
K02153 ATPeV0E, ATP6H; V-type H+-transporting ATPase subunit e
K02155 ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
K03661 ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
K03662 ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04345 PKA; protein kinase A [EC:2.7.11.11]
K02159 BAX; apoptosis regulator BAX
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K10691 UBR4, ZUBR1; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
K10389 TUBG; tubulin gamma
K00873 PK, pyk; pyruvate kinase [EC:2.7.1.40]
K05414 IFNA; interferon alpha
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K14608 OASL; 2'-5'-oligoadenylate synthase-like protein
K14754 MX; interferon-induced GTP-binding protein Mx
K12159 ISG15; ubiquitin cross-reactive protein
K06052 JAG1, CD339; jagged-1
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K05948 FNG; fringe [EC:2.4.1.222]
K06061 MAML; mastermind
K06053 RBPSUH, RBPJK; recombining binding protein suppressor of hairless
K06054 HES1; hairy and enhancer of split 1
K09087 HES2_6_7; hairy and enhancer of split 2/6/7
K09088 HES3; hairy and enhancer of split 3
K09089 HES4; hairy and enhancer of split 4
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
|
|
09171 Infectious disease: bacterial
|
05110 Vibrio cholerae infection [PATH:ko05110]
|
05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
|
05130 Pathogenic Escherichia coli infection [PATH:ko05130]
|
K11006 stxA; shiga toxin subunit A
K11007 stxB; shiga toxin subunit B
K06856 IGH; immunoglobulin heavy chain
K23648 espJ; T3SS secreted effector ADP-ribosyltransferase EspJ
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K18441 CYTH; cytohesin
K07941 ARF6; ADP-ribosylation factor 6
K07937 ARF1_2; ADP-ribosylation factor 1/2
K05750 NCKAP1, NAP125; NCK-associated protein 1
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K23649 ABI1; abl interactor 1
K05752 C3ORF10, HSPC300; chromosome 3 open reading frame 10
K05753 WASF1; WAS protein family, member 1
K05748 WASF2; WAS protein family, member 2
K06083 WASF3; WAS protein family, member 3
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K04513 RHOA; Ras homolog gene family, member A
K04393 CDC42; cell division control protein 42
K12785 espG, virA; LEE-encoded effector EspG
K12788 espH; LEE-encoded effector EspH
K10356 MYO1; myosin I
K10357 MYO5; myosin V
K10358 MYO6; myosin VI
K12559 MYO10; myosin X
K10352 MYH9s; myosin heavy chain 9/10/11/14
K23650 espB; LEE-encoded effector EspB
K23651 espT; T3SS secreted effector EspT
K23652 espW; T3SS secreted effector EspW
K12787 map; LEE-encoded effector Map
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K13365 SLC9A3R1, NHERF1; sodium/hydrogen exchange regulatory cofactor NHE-RF1
K08007 EZR, VIL2; ezrin
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12809 espG2; T3SS secreted effector EspG-like protein
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K12791 ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
K23653 espM; T3SS effector EspM
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K12790 eae; intimin
K12784 tir; translocated intimin receptor
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K20127 BAIAP2L1, IRTKS; BAI1-associated protein 2-like protein 1
K05627 BAIAP2, IRSP53; BAI1-associated protein 2
K12789 tccP; Tir-cytoskeleton coupling protein
K07365 NCK1; NCK adaptor protein 1
K19862 NCK2, GRB4; NCK adaptor protein 2
K19475 WIPF; WAS/WASL-interacting protein
K06106 CTTN, EMS1; cortactin
K11294 NCL, NSR1; nucleolin
K05719 ITGB1, CD29; integrin beta 1
K12810 bfpA; major structural subunit of bundle-forming pilus
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K10160 TLR4, CD284; toll-like receptor 4
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K10168 TLR5; toll-like receptor 5
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K00134 GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02985 RP-S3e, RPS3; small subunit ribosomal protein S3e
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K23654 nleE, ospZ; T3SS secreted effector NleE
K16042 nleH; non-LEE-encoded effector NleH
K23655 nleC; T3SS secreted effector NleC
K23656 nleD; T3SS secreted effector NleD
K23657 nleB; T3SS secreted effector NleB
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K21889 TMBIM6, BI1, TEGT; Bax inhibitor 1
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K02159 BAX; apoptosis regulator BAX
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K06185 ABCF2; ATP-binding cassette, subfamily F, member 2
K23658 nleF; T3SS secreted effector NleF
K23659 espZ; LEE-encoded effector EspZ
K23660 cif; cell inhibiting factor
K12786 espF; LEE-encoded effector EspF
K03221 yscF, sctF, ssaG, prgI; type III secretion protein F
K22487 prgJ; type III secretion system protein
K23661 escI; type III secretion system protein
K12807 NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
K22265 NLRP4; NACHT, LRR and PYD domains-containing protein 4
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K04394 CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
K05482 IL18, IL1F4; interleukin 18
K16041 nleA; non-LEE-encoded effector NleA
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K07874 RAB1A; Ras-related protein Rab-1A
K14007 SEC24; protein transport protein SEC24
K20352 TMED10, ERV25; p24 family protein delta-1
K06088 OCLN; occludin
K06087 CLDN; claudin
K05701 TJP1, ZO1; tight junction protein 1
|
05132 Salmonella infection [PATH:ko05132]
|
K11014 cdtB; cytolethal distending toxin subunit B
K11023 ptxA, artA, pltA; pertussis toxin subunit 1 [EC:2.4.2.-]
K19298 subB, artB, pltB; subtilase cytotoxin, subunit B
K06817 PODXL; podocalyxin-like
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K13085 ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78]
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K15347 sifA; secreted effector protein SifA
K07897 RAB7A; Ras-related protein Rab-7A
K07898 RAB7B; Ras-related protein Rab-7B
K23282 PLEKHM1; pleckstrin homology domain-containing family M member 1
K20179 VPS11, PEP5; vacuolar protein sorting-associated protein 11
K20180 VPS16; vacuolar protein sorting-associated protein 16
K20181 VPS18, PEP3; vacuolar protein sorting-associated protein 18
K20182 VPS33A; vacuolar protein sorting-associated protein 33A
K20183 VPS39, VAM6; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
K20184 VPS41; vacuolar protein sorting-associated protein 41
K23936 sopD2; secreted effector protein SopD2
K13883 RILP; Rab-interacting lysosomal protein
K10413 DYNC1H; dynein cytoplasmic 1 heavy chain
K10414 DYNC2H, DNCH2; dynein cytoplasmic 2 heavy chain
K10415 DYNC1I, DNCI; dynein cytoplasmic 1 intermediate chain
K10416 DYNC1LI, DNCLI; dynein cytoplasmic 1 light intermediate chain
K10417 DYNC2LI; dynein cytoplasmic 2 light intermediate chain
K10418 DYNLL; dynein light chain LC8-type
K10419 DYNLRB, DNCL2; dynein light chain roadblock-type
K10420 DYNLT1_3; dynein light chain Tctex-type 1/3
K04648 DCTN1; dynactin 1
K10424 DCTN2; dynactin 2
K10425 DCTN3; dynactin 3
K10426 DCTN4; dynactin 4
K10427 DCTN5; dynactin 5
K10428 DCTN6; dynactin 6
K16575 ACTR1, ARP1; centractin
K16576 ACTR10, ARP11; actin-related protein 10
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K21954 FYCO1; FYVE and coiled-coil domain-containing protein 1
K07955 ARL8; ADP-ribosylation factor-like protein 8
K15348 PLEKHM2, SKIP; pleckstrin homology domain-containing family M member 2
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K15352 pipB2; secreted effector protein PipB2
K15350 sseF; secreted effector protein SseF
K15351 sseG; secreted effector protein SseG
K23935 ACBD3; golgi resident protein GCP60
K04513 RHOA; Ras homolog gene family, member A
K15349 sseJ; secreted effector protein SseJ
K10089 M6PR; cation-dependent mannose-6-phosphate receptor
K07899 RAB9A, RAB9; Ras-related protein Rab-9A
K07900 RAB9B; Ras-related protein Rab-9B
K20282 GCC2; GRIP and coiled-coil domain-containing protein 2
K23937 STX10; syntaxin 10
K15353 sspH2; E3 ubiquitin-protein ligase SspH2
K15354 sseI, srfH; secreted effector protein SseI
K05759 PFN; profilin
K04437 FLNA; filamin-A
K15366 spvB; salmonella plasmid virulence protein B
K07195 EXOC7, EXO70; exocyst complex component 7
K19984 EXOC5, SEC10; exocyst complex component 5
K06111 EXOC4, SEC8; exocyst complex component 4
K17637 EXOC2, SEC5; exocyst complex component 2
K07834 RALA; Ras-related protein Ral-A
K13286 sipC, ipaC, bipC; invasin C
K13284 sipA, ipaA; invasin A
K05692 ACTB_G1; actin beta/gamma 1
K17274 S100A10; protein S100-A10
K17092 ANXA2; annexin A2
K23934 AHNAK; neuroblast differentiation-associated protein AHNAK
K13741 sopE; guanine nucleotide exchange factor SopE
K13740 sptP; secreted effector protein SptP
K07864 RHOJ, TCL; Ras homolog gene family, member J
K13744 ARHGEF26, SGEF; Rho guanine nucleotide exchange factor 26
K07863 RHOG; Ras homolog gene family, member G
K12366 ELMO1, CED12; engulfment and cell motility protein 1
K18985 ELMO2, CED12A; engulfment and cell motility protein 2
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K23938 FHOD1; FH1/FH2 domain-containing protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K05750 NCKAP1, NAP125; NCK-associated protein 1
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K23649 ABI1; abl interactor 1
K05752 C3ORF10, HSPC300; chromosome 3 open reading frame 10
K06083 WASF3; WAS protein family, member 3
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K10358 MYO6; myosin VI
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K00923 PIK3C2; phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
K18441 CYTH; cytohesin
K07941 ARF6; ADP-ribosylation factor 6
K07937 ARF1_2; ADP-ribosylation factor 1/2
K17923 SNX9_18_33; sorting nexin-9/18/33
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K23484 DNM2; dynamin 2 [EC:3.6.5.5]
K10169 TLR6, CD286; toll-like receptor 6
K10159 TLR2, CD282; toll-like receptor 2
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04391 CD14; monocyte differentiation antigen CD14
K10160 TLR4, CD284; toll-like receptor 4
K05400 LY96, MD-2; lymphocyte antigen 96
K02406 fliC, hag; flagellin
K10168 TLR5; toll-like receptor 5
K10161 TLR9, CD289; toll-like receptor 9
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K08727 NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K18423 CSE1, CAS, XPO2; exportin-2 (importin alpha re-exporter)
K23940 KPNA1; importin subunit alpha-5
K23583 KPNA3_4; importin subunit alpha-4/3
K02985 RP-S3e, RPS3; small subunit ribosomal protein S3e
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K02105 CTNNB1; catenin beta 1
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K19557 spvD; salmonella plasmid virulence protein D
K23941 pipA, gogA, gtgA; PipA/GogA/GtgA family effector protease
K15343 sspH1; E3 ubiquitin-protein ligase SspH1
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23942 gogB; Gifsy-1 prophage leucine-rich repeat protein
K10302 FBXO22; F-box protein 22
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K08598 yopJ; YopJ protease family
K18015 elaD, sseL; deubiquitinase [EC:3.4.22.-]
K13450 ospF, mkaD, spvC; phosphothreonine lyase [EC:4.2.3.-]
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K00134 GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K02161 BCL2; apoptosis regulator Bcl-2
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K07856 RHOB; Ras homolog gene family, member B
K07873 RHOH, TTF; Ras homolog gene family, member H
K07829 RRAS; Ras-related protein R-Ras
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K23943 sseK3; type III secretion system effector arginine glycosyltransferase
K23944 sseK1; type III secretion system effector arginine glycosyltransferase
K23945 sseK2; type III secretion system effector
K23946 slrP; E3 ubiquitin-protein ligase SlrP [EC:2.3.2.27]
K03671 TXN, trxA; thioredoxin
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K22487 prgJ; type III secretion system protein
K03221 yscF, sctF, ssaG, prgI; type III secretion protein F
K12807 NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
K12805 NLRC4, CARD12; NLR family CARD domain-containing protein 4
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05482 IL18, IL1F4; interleukin 18
K04394 CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
K04395 CASP5; caspase 5 [EC:3.4.22.58]
K20917 GSDMD; gasdermin-D
K13285 sipB, ipaB, bipB; invasin B
|
05131 Shigellosis [PATH:ko05131]
|
05135 Yersinia infection [PATH:ko05135]
|
05133 Pertussis [PATH:ko05133]
|
05134 Legionellosis [PATH:ko05134]
|
05150 Staphylococcus aureus infection [PATH:ko05150]
|
05152 Tuberculosis [PATH:ko05152]
|
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02084 APAF1; apoptotic protease-activating factor
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K02161 BCL2; apoptosis regulator Bcl-2
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K08061 RFX5; regulatory factor X 5
K08062 RFXANK; regulatory factor X-associated ankyrin-containing protein
K08063 RFXAP; regulatory factor X-associated protein
K08064 NFYA, HAP2; nuclear transcription factor Y, alpha
K08065 NFYB, HAP3; nuclear transcription Y subunit beta
K08066 NFYC, HAP5; nuclear transcription factor Y, gamma
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K06752 MHC2; MHC class II antigen
K06505 CD74, DHLAG; CD74 antigen
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K05443 IL10, CSIF; interleukin 10
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K01368 CTSS; cathepsin S [EC:3.4.22.27]
K10059 CLEC4E, MINCLE; C-type lectin domain family 4 member E
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K10074 CLEC7A, DECTIN1, CD369; C-type lectin domain family 7 member A
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K12794 CARD9; caspase recruitment domain-containing protein 9
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K07368 BCL10; B-cell CLL/lymphoma 10
K14952 namH; UDP-MurNAc hydroxylase
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K14953 lpqH; ipoprotein LpqH
K14954 lprG; lipoprotein LprG
K14955 lprA; lipoprotein LprA
K02040 pstS; phosphate transport system substrate-binding protein
K04043 dnaK, HSPA9; molecular chaperone DnaK
K04077 groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
K14956 esx, esat6, cfp10; ESAT-6 family protein
K05399 LBP; lipopolysaccharide-binding protein
K10159 TLR2, CD282; toll-like receptor 2
K05398 TLR1, CD281; toll-like receptor 1
K10169 TLR6, CD286; toll-like receptor 6
K10160 TLR4, CD284; toll-like receptor 4
K04391 CD14; monocyte differentiation antigen CD14
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05482 IL18, IL1F4; interleukin 18
K05426 IL23A; interleukin 23 subunit alpha
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K10049 CEBPG; CCAAT/enhancer binding protein (C/EBP), gamma
K10161 TLR9, CD289; toll-like receptor 9
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K06563 CLEC4L_M, DC-SIGN, CD209, CD299; C-type lectin domain family 4 member L/M
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K04513 RHOA; Ras homolog gene family, member A
K14957 LSP1; lymphocyte-specific protein 1
K08862 PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
K14958 KSR1; kinase suppressor of Ras 1
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K07438 CYP27B1; calcidiol 1-monooxygenase (25-hydroxyvitamin D3 1alpha-hydroxylase) [EC:1.14.15.18]
K08539 VDR, NR1I1; vitamin D3 receptor
K13916 CAMP, LL37; cathelicidin antimicrobial peptide
K03990 C3; complement component 3
K04011 CR1, CD35; complement component (3b/4b) receptor 1
K06462 ITGAX, CD11c; integrin alpha X
K06464 ITGB2, CD18; integrin beta 2
K06461 ITGAM, CD11b; integrin alpha M
K06560 MRC, CD206, CD280; mannose receptor, C type
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K02183 CALM; calmodulin
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K12478 EEA1; early endosome antigen 1
K07897 RAB7A; Ras-related protein Rab-7A
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K02154 ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
K02146 ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K03662 ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
K02155 ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
K03661 ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
K06528 LAMP1_2, CD107; lysosomal-associated membrane protein 1/2
K21302 sapM; phosphatidylinositol-3-phosphatase [EC:3.1.3.64]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K13882 CORO1A; coronin-1A
K14949 pknG; serine/threonine-protein kinase PknG [EC:2.7.11.1]
K06856 IGH; immunoglobulin heavy chain
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K12560 FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
K16824 FCGR2C, CD32; low affinity immunoglobulin gamma Fc receptor II-c
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
|
05100 Bacterial invasion of epithelial cells [PATH:ko05100]
|
|
09174 Infectious disease: parasitic
|
05146 Amoebiasis [PATH:ko05146]
|
05144 Malaria [PATH:ko05144]
|
05145 Toxoplasmosis [PATH:ko05145]
|
05140 Leishmaniasis [PATH:ko05140]
|
05142 Chagas disease [PATH:ko05142]
|
K10160 TLR4, CD284; toll-like receptor 4
K05842 TRIF; toll-like receptor adapter molecule 1
K13729 TCAC2, TC52; thiol-dependent reductase 1
K10159 TLR2, CD282; toll-like receptor 2
K10169 TLR6, CD286; toll-like receptor 6
K10161 TLR9, CD289; toll-like receptor 9
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05415 IFNB; interferon beta
K12499 CCL5; C-C motif chemokine 5
K14624 CCL2, MCP1; C-C motif chemokine 2
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K05408 CCL3; C-C motif chemokine 3
K04519 IL1B; interleukin 1 beta
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K23590 CRP; complement regulatory protein
K03990 C3; complement component 3
K08057 CALR; calreticulin
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K08571 E3.4.22.51; cruzipain [EC:3.4.22.51]
K05443 IL10, CSIF; interleukin 10
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K01283 ACE, CD143; peptidyl-dipeptidase A [EC:3.4.15.1]
K03898 KNG, BK; kininogen
K03916 BDKRB2; bradykinin receptor B2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04636 GNA14; guanine nucleotide-binding protein subunit alpha-14
K04637 GNA15; guanine nucleotide-binding protein subunit alpha-15
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K23591 TS; trans-sialidase [EC:3.2.1.-]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K05429 IL2; interleukin 2
|
05143 African trypanosomiasis [PATH:ko05143]
|
|
09163 Immune disease
|
|
09164 Neurodegenerative disease
|
05010 Alzheimer disease [PATH:ko05010]
|
K06704 ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
K06059 ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
K04520 APP; amyloid beta A4 protein
K04532 NAE1, APPBP1; NEDD8-activating enzyme E1 regulatory subunit
K04529 APBB1, FE65; amyloid beta A4 precursor protein-binding family B member 1
K00134 GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K04521 BACE1; beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46]
K07747 BACE2; beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45]
K20723 RTN3; reticulon-3
K20720 RTN4; reticulon-4
K06170 PSENEN, PEN2; presenilin enhancer 2
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2, PS2; presenilin 2 [EC:3.4.23.-]
K06171 NCSTN; nicastrin
K06172 APH1; gamma-secretase subunit APH-1
K01408 IDE, ide; insulysin [EC:3.4.24.56]
K01389 MME, CD10; neprilysin [EC:3.4.24.11]
K04380 MAPT, TAU; microtubule-associated protein tau
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K08683 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
K05864 PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K01059 LPL; lipoprotein lipase [EC:3.1.1.34]
K04524 APOE; apolipoprotein E
K04550 LRP1, CD91; low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K02158 BAD; Bcl-2-antagonist of cell death
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04133 CHRM5; muscarinic acetylcholine receptor M5
K04604 GRM5; metabotropic glutamate receptor 5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K20858 MCU; calcium uniporter protein, mitochondrial
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04963 RYR3; ryanodine receptor 3
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K09027 XBP1; X box-binding protein 1
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K11716 CDK5R1; cyclin-dependent kinase 5 activator 1
K14709 SLC39A1_2_3, ZIP1_2_3; solute carrier family 39 (zinc transporter), member 1/2/3
K14710 SLC39A4, ZIP4; solute carrier family 39 (zinc transporter), member 4
K14711 SLC39A5, ZIP5; solute carrier family 39 (zinc transporter), member 5
K14712 SLC39A6, LIV1, ZIP6; solute carrier family 39 (zinc transporter), member 6
K14713 SLC39A7, KE4, ZIP7; solute carrier family 39 (zinc transporter), member 7
K14714 SLC39A8, ZIP8; solute carrier family 39 (zinc transporter), member 8
K14715 SLC39A9, ZIP9; solute carrier family 39 (zinc transporter), member 9
K14716 SLC39A10, ZIP10; solute carrier family 39 (zinc transporter), member 10
K14717 SLC39A11, ZIP11; solute carrier family 39 (zinc transporter), member 11
K14718 SLC39A12, ZIP12; solute carrier family 39 (zinc transporter), member 12
K14719 SLC39A13, ZIP13; solute carrier family 39 (zinc transporter), member 13
K14720 SLC39A14, ZIP14; solute carrier family 39 (zinc transporter), member 14
K21398 SLC11A2, DMT1, NRAMP2; natural resistance-associated macrophage protein 2
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02165 DKK1_2_4; dickkopf 1/2/4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K04690 FZDN, fz3; frizzled
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K08008 NOX1, MOX1; NADPH oxidase 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K21423 NOX4, RENOX; NADPH oxidase 4 [EC:1.6.3.-]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K04528 SNCA; alpha-synuclein
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04526 INS; insulin
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K19730 ATG101; autophagy-related protein 101
K08331 ATG13; autophagy-related protein 13
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K08334 BECN, VPS30, ATG6; beclin
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K21246 NRBF2; nuclear receptor-binding factor 2
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K17906 ATG2; autophagy-related protein 2
K17908 WIPI1_2, ATG18; autophagy-related protein 18
|
05012 Parkinson disease [PATH:ko05012]
|
05014 Amyotrophic lateral sclerosis [PATH:ko05014]
|
05016 Huntington disease [PATH:ko05016]
|
05017 Spinocerebellar ataxia [PATH:ko05017]
|
05020 Prion disease [PATH:ko05020]
|
05022 Pathways of neurodegeneration - multiple diseases [PATH:ko05022]
|
K04520 APP; amyloid beta A4 protein
K04380 MAPT, TAU; microtubule-associated protein tau
K04528 SNCA; alpha-synuclein
K23600 TARDBP, TDP43; TAR DNA-binding protein 43
K13098 TLS, FUS; RNA-binding protein FUS
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K23625 ATXN2_2L; ataxin 2/2L
K04533 HD; huntingtin
K23616 ATXN1_1L; ataxin 1/1L
K11863 ATXN3, MJD; Ataxin-3 [EC:3.4.22.-]
K05634 PRNP, PrP, CD230; prion protein
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04133 CHRM5; muscarinic acetylcholine receptor M5
K23932 SPTBN2; spectrin beta, non-erythrocytic 2
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04556 PARK2; parkin [EC:2.3.2.31]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04966 TRPC3; transient receptor potential cation channel subfamily C member 3
K20719 SIGMAR1; sigma non-opioid intracellular receptor
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K15840 PDYN, PENKB; proenkephalin B (prodynorphin)
K11828 DLG4, PSD95; discs large protein 4
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04560 STX1A; syntaxin 1A
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2, PS2; presenilin 2 [EC:3.4.23.-]
K11519 DERL1; Derlin-1
K13525 VCP, CDC48; transitional endoplasmic reticulum ATPase
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
K03178 UBE1, UBA1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
K10698 UBE1L, UBA7; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]
K04552 UBE2L3, UBCH7; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
K04553 UBE2L6, UBCH8; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
K04554 UBE2J2, NCUBE2, UBC6; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
K10578 UBE2J1, NCUBE1, UBC6; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
K04555 UBE2G2, UBC7; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
K10575 UBE2G1, UBC7; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
K04243 GPR37; prosaposin receptor
K04557 SEPT5, PNUTL1, CDCREL1; septin 5
K04558 SNCAIP; synphilin-1
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K10707 VAPB, ALS8; vesicle-associated membrane protein-associated protein B
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K09027 XBP1; X box-binding protein 1
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K04418 MAP3K10, MLK2; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K05036 SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K02161 BCL2; apoptosis regulator Bcl-2
K05862 VDAC1; voltage-dependent anion channel protein 1
K11518 TOM40; mitochondrial import receptor subunit TOM40
K20858 MCU; calcium uniporter protein, mitochondrial
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K02158 BAD; Bcl-2-antagonist of cell death
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
K08669 HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
K09488 TRAP1, HSP75; TNF receptor-associated protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04559 HIP1; huntingtin interacting protein 1
K04638 IFT57, HIPPI, ESRRBL1; intraflagellar transport protein 57
K08683 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
K05864 PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05687 PARK7; protein DJ-1 [EC:3.5.1.124]
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
K06030 MFN2, FZO1; mitofusin 2 [EC:3.6.5.-]
K19946 OPTN, FIP2; optineurin
K14381 SQSTM1; sequestosome 1
K10435 MAP1LC; microtubule-associated protein 1 light chain
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K23610 WDR41; WD repeat-containing protein 41
K23611 SMCR8; guanine nucleotide exchange protein SMCR8
K23609 C9ORF72; guanine nucleotide exchange protein C9orf72
K07901 RAB8A, MEL; Ras-related protein Rab-8A
K07925 RAB39B; Ras-related protein Rab-39B
K07874 RAB1A; Ras-related protein Rab-1A
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K19730 ATG101; autophagy-related protein 101
K08331 ATG13; autophagy-related protein 13
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K08334 BECN, VPS30, ATG6; beclin
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K21246 NRBF2; nuclear receptor-binding factor 2
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K17906 ATG2; autophagy-related protein 2
K17908 WIPI1_2, ATG18; autophagy-related protein 18
K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
K04575 ALS2; amyotrophic lateral sclerosis 2 protein
K07887 RAB5A; Ras-related protein Rab-5A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K12192 CHMP2B; charged multivesicular body protein 2B
K22913 FIG4; phosphatidylinositol 3,5-bisphosphate 5-phosphatase [EC:3.1.3.-]
K19026 SPG11; spatacsin
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K02308 DAXX; death-associated protein 6
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K04569 CCS; copper chaperone for superoxide dismutase
K00432 gpx, btuE, bsaA; glutathione peroxidase [EC:1.11.1.9]
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K07607 PRPH; peripherin
K04572 NEFL, NF-L; neurofilament light polypeptide
K04573 NEF3, NF-M; neurofilament medium polypeptide (neurofilament 3)
K04574 NEFH, NF-H; neurofilament heavy polypeptide
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K04355 BDNF; brain-derived neurotrophic factor
K04648 DCTN1; dynactin 1
K10424 DCTN2; dynactin 2
K10425 DCTN3; dynactin 3
K10426 DCTN4; dynactin 4
K10427 DCTN5; dynactin 5
K10428 DCTN6; dynactin 6
K16575 ACTR1, ARP1; centractin
K16576 ACTR10, ARP11; actin-related protein 10
K04647 HAP1; huntingtin-associated protein 1
K10408 DNAH; dynein axonemal heavy chain
K10410 DNALI; dynein axonemal light intermediate chain 1
K10409 DNAI1; dynein axonemal intermediate chain 1
K11143 DNAI2; dynein axonemal intermediate chain 2
K10411 DNAL1; dynein axonemal light chain 1
K10412 DNAL4; dynein axonemal light chain 4
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K11716 CDK5R1; cyclin-dependent kinase 5 activator 1
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02165 DKK1_2_4; dickkopf 1/2/4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K04690 FZDN, fz3; frizzled
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08008 NOX1, MOX1; NADPH oxidase 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K21423 NOX4, RENOX; NADPH oxidase 4 [EC:1.6.3.-]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
|
|
09165 Substance dependence
|
|
09166 Cardiovascular disease
|
|
09167 Endocrine and metabolic disease
|
04930 Type II diabetes mellitus [PATH:ko04930]
|
04940 Type I diabetes mellitus [PATH:ko04940]
|
04950 Maturity onset diabetes of the young [PATH:ko04950]
|
04936 Alcoholic liver disease [PATH:ko04936]
|
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K01332 C2; complement component 2 [EC:3.4.21.43]
K03989 C4; complement component 4
K03990 C3; complement component 3
K04009 C3AR1; C3a anaphylatoxin chemotactic receptor
K03994 C5; complement component 5
K04010 C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
K05399 LBP; lipopolysaccharide-binding protein
K04391 CD14; monocyte differentiation antigen CD14
K05400 LY96, MD-2; lymphocyte antigen 96
K10160 TLR4, CD284; toll-like receptor 4
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K10030 IL8, CXCL8; interleukin 8
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05489 IL17A, CTLA8; interleukin 17A
K05164 IL17RA, CD217; interleukin 17 receptor A
K05166 IL17RC, IL17RL; interleukin 17 receptor C
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K07197 SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00507 SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K17125 MIR217; microRNA 217
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K12897 TRA2; transformer-2 protein
K07296 ADIPOQ, ACDC; adiponectin
K07297 ADIPOR; adiponectin receptor
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K07202 PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K09479 ACADVL; very long chain acyl-CoA dehydrogenase [EC:1.3.8.9]
K00249 ACADM, acd; acyl-CoA dehydrogenase [EC:1.3.8.7]
K00232 E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6]
K08750 FABP1, L-FABP; fatty acid-binding protein 1, liver
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA, ADH5, adhC; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K13952 ADH6; alcohol dehydrogenase 6 [EC:1.1.1.1]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K14085 ALDH7A1; aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
K00149 ALDH9A1; aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K21423 NOX4, RENOX; NADPH oxidase 4 [EC:1.6.3.-]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
|
04932 Non-alcoholic fatty liver disease [PATH:ko04932]
|
04931 Insulin resistance [PATH:ko04931]
|
04933 AGE-RAGE signaling pathway in diabetic complications [PATH:ko04933]
|
04934 Cushing syndrome [PATH:ko04934]
|
|
09175 Drug resistance: antimicrobial
|
|
09176 Drug resistance: antineoplastic
|
01521 EGFR tyrosine kinase inhibitor resistance [PATH:ko01521]
|
01524 Platinum drug resistance [PATH:ko01524]
|
K14686 SLC31A1, CTR1; solute carrier family 31 (copper transporter), member 1
K17686 copA, ctpA, ATP7; P-type Cu+ transporter [EC:7.2.2.8]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K02350 REV3L, POLZ; DNA polymerase zeta [EC:2.7.7.7]
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08734 MLH1; DNA mismatch repair protein MLH1
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3, PUMA; Bcl-2-binding component 3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
|
01523 Antifolate resistance [PATH:ko01523]
|
01522 Endocrine resistance [PATH:ko01522]
|
|
09180 Brite Hierarchies
|
|
09190 Not Included in Pathway or Brite
|
KEGG Orthology (KO)