 09100 Metabolism
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 09120 Genetic Information Processing
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09121 Transcription
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09122 Translation
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09123 Folding, sorting and degradation
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03060 Protein export [PATH:ko03060]
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04141 Protein processing in endoplasmic reticulum [PATH:ko04141]
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 K10956 SEC61A; protein transport protein SEC61 subunit alpha
K09481 SEC61B, SBH2; protein transport protein SEC61 subunit beta
K07342 SEC61G, SSS1, secE; protein transport protein SEC61 subunit gamma and related proteins
K12275 SEC62; translocation protein SEC62
K09540 SEC63, DNAJC23; translocation protein SEC63
K12666 RPN1, OST1; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit 1 (ribophorin I)
K12667 RPN2, SWP1; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit 2 (ribophorin II)
K12668 DAD1, OST2; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit DAD1/OST2
K12669 OST3_6; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit 3/6
K12670 DDOST, WBP1; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit DDOST/WBP1
K00730 OST4; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit 4
K12691 OST5; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit 5
K07151 STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]
K19478 MAGT1, TUSC3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit MAGT1/TUSC3
K26501 OSTC; oligosaccharyltransferase complex subunit OSTC
K26502 TMEM258; transmembrane protein 258
K01228 MOGS; mannosyl-oligosaccharide glucosidase [EC:3.2.1.106]
K13999 CKAP4, CLIMP63; cytoskeleton-associated protein 4
K14000 RRBP1; ribosome-binding protein 1
K14001 SIL1, SLS1; nucleotide exchange factor SIL1
K09486 HYOU1; hypoxia up-regulated 1
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K09517 DNAJB11; DnaJ homolog subfamily B member 11
K09521 DNAJC1; DnaJ homolog subfamily C member 1
K09523 DNAJC3; DnaJ homolog subfamily C member 3
K09530 DNAJC10; DnaJ homolog subfamily C member 10 [EC:1.8.4.-]
K14002 SCJ1; DnaJ-related protein SCJ1
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K05546 GANAB; mannosyl-oligosaccharide alpha-1,3-glucosidase [EC:3.2.1.207]
K08288 PRKCSH; protein kinase C substrate 80K-H
K08054 CANX; calnexin
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K01230 MAN1A_C, MNS1_2; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
K23741 MAN1B, MNS3; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]
K10082 LMAN2, VIP36; lectin, mannose-binding 2
K10080 LMAN1, ERGIC53; lectin, mannose-binding 1
K10081 LMAN1L, ERGL; lectin, mannose-binding 1-like
K14003 PREB, SEC12; prolactin regulatory element-binding protein
K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
K14004 SEC13; protein transport protein SEC13
K14005 SEC31; protein transport protein SEC31
K14006 SEC23; protein transport protein SEC23
K14007 SEC24; protein transport protein SEC24
K11718 HUGT; UDP-glucose:glycoprotein glucosyltransferase [EC:2.4.1.-]
K10084 EDEM1; ER degradation enhancer, mannosidase alpha-like 1
K10085 EDEM2; ER degradation enhancer, mannosidase alpha-like 2
K10086 EDEM3; ER degradation enhancer, mannosidase alpha-like 3
K09580 PDIA1, P4HB; protein disulfide-isomerase A1 [EC:5.3.4.1]
K09582 PDIA4, ERP72; protein disulfide-isomerase A4 [EC:5.3.4.1]
K09584 PDIA6, TXNDC7; protein disulfide-isomerase A6 [EC:5.3.4.1]
K13996 EPS1; protein disulfide-isomerase [EC:5.3.4.1]
K09586 ERP29; endoplasmic reticulum protein 29
K13984 TXNDC5, ERP46; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
K10950 ERO1L; ERO1-like protein alpha [EC:1.8.4.-]
K10976 ERO1LB; ERO1-like protein beta [EC:1.8.4.-]
K10088 OS9; protein OS-9
K14008 ERLEC1, XTP3B; endoplasmic reticulum lectin 1
K13249 SSR1; translocon-associated protein subunit alpha
K13250 SSR2; translocon-associated protein subunit beta
K13251 SSR3; translocon-associated protein subunit gamma
K04571 SSR4; translocon-associated protein subunit delta
K14009 BCAP31, BAP31; B-cell receptor-associated protein 31
K14010 TRAM1; translocating chain-associated membrane protein 1
K11519 DERL1; Derlin-1
K13989 DERL2_3; Derlin-2/3
K24348 UBXN1_4; UBX domain-containing protein 1/4
K24349 UBXN2A; UBX domain-containing protein 2A
K14011 UBXN6, UBXD1; UBX domain-containing protein 6
K24351 UBXN8; UBX domain-containing protein 8
K14012 NSFL1C, UBX1, SHP1; UBX domain-containing protein 1
K14013 UBX2, SEL1; UBX domain-containing protein 2
K14014 SVIP; small VCP/p97-interacting protein
K13525 VCP, CDC48; transitional endoplasmic reticulum ATPase
K14015 NPLOC4, NPL4; nuclear protein localization protein 4
K14016 UFD1; ubiquitin fusion degradation protein 1
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K09502 DNAJA1; DnaJ homolog subfamily A member 1
K09503 DNAJA2; DnaJ homolog subfamily A member 2
K09507 DNAJB1; DnaJ homolog subfamily B member 1
K09508 DNAJB2; DnaJ homolog subfamily B member 2
K09518 DNAJB12; DnaJ homolog subfamily B member 12
K09525 DNAJC5; DnaJ homolog subfamily C member 5
K04079 HSP90A, htpG; molecular chaperone HtpG
K09485 HSP110; heat shock protein 110kDa
K09555 BAG1; BCL2-associated athanogene 1
K09556 BAG2; BCL2-associated athanogene 2
K09562 HSPBP1, FES1; hsp70-interacting protein
K14017 SNL1; HSP70 co-chaperone SNL1
K09541 CRYAA; crystallin, alpha A
K09542 CRYAB; crystallin, alpha B
K13993 HSP20; HSP20 family protein
K13719 OTU1, YOD1; ubiquitin thioesterase OTU1 [EC:3.1.2.-]
K14018 PLAA, DOA1, UFD3; phospholipase A-2-activating protein
K10839 RAD23, HR23; UV excision repair protein RAD23
K04523 UBQLN, DSK2; ubiquilin
K01456 E3.5.1.52, NGLY1, PNG1; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase [EC:3.5.1.52]
K11863 ATXN3, MJD; Ataxin-3 [EC:3.4.22.-]
K10597 UBE4B, UFD2; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K14019 PPP1R15A, GADD34; protein phosphatase 1 regulatory subunit 15A
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K02161 BCL2; apoptosis regulator Bcl-2
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K14020 WFS1; wolfamin
K08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
K07765 MBTPS2; S2P endopeptidase [EC:3.4.24.85]
K09027 XBP1; X box-binding protein 1
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K10661 MARCH6, DOA10; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
K10578 UBE2J1, NCUBE1, UBC6; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
K04554 UBE2J2, NCUBE2, UBC6; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
K10575 UBE2G1, UBC7; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
K04555 UBE2G2, UBC7; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
K14022 CUE1, KIS4; coupling of ubiquitin conjugation to ER degradation protein 1
K14023 HRD3; ERAD-associated E3 ubiquitin-protein ligase component HRD3
K10601 SYVN1, HRD1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
K14024 USA1; U1 SNP1-associating protein 1
K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
K14025 SELS, VIMP; selenoprotein S
K14026 SEL1, SEL1L; SEL1 protein
K14027 HERPUD1, HERP; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
K10636 AMFR, GP78; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
K09561 STUB1, CHIP; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
K06689 UBE2D, UBC4, UBC5; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K04556 PARK2; parkin [EC:2.3.2.31]
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03347 CUL1, CDC53; cullin 1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K10099 FBXO2, NFB42; F-box protein 2
K10100 FBXO6; F-box protein 6
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04130 SNARE interactions in vesicular transport [PATH:ko04130]
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04120 Ubiquitin mediated proteolysis [PATH:ko04120]
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04122 Sulfur relay system [PATH:ko04122]
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03050 Proteasome [PATH:ko03050]
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03018 RNA degradation [PATH:ko03018]
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09124 Replication and repair
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09126 Chromosome
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09125 Information processing in viruses
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09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system [PATH:ko02020]
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04010 MAPK signaling pathway [PATH:ko04010]
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K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04852 CACNA1E, CAV2.3; voltage-dependent calcium channel R type alpha-1E
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04854 CACNA1G, CAV3.1; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H, CAV3.2; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I, CAV3.3; voltage-dependent calcium channel T type alpha-1I
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04858 CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
K04859 CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
K04860 CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
K04861 CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
K04862 CACNB1; voltage-dependent calcium channel beta-1
K04863 CACNB2; voltage-dependent calcium channel beta-2
K04864 CACNB3; voltage-dependent calcium channel beta-3
K04865 CACNB4; voltage-dependent calcium channel beta-4
K04866 CACNG1; voltage-dependent calcium channel gamma-1
K04867 CACNG2; voltage-dependent calcium channel gamma-2
K04868 CACNG3; voltage-dependent calcium channel gamma-3
K04869 CACNG4; voltage-dependent calcium channel gamma-4
K04870 CACNG5; voltage-dependent calcium channel gamma-5
K04871 CACNG6; voltage-dependent calcium channel gamma-6
K04872 CACNG7; voltage-dependent calcium channel gamma-7
K04873 CACNG8; voltage-dependent calcium channel gamma-8
K04345 PKA; protein kinase A [EC:2.7.11.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K12326 RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K08018 RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
K08052 NF1; neurofibromin 1
K04352 RASA1, RASGAP; Ras GTPase-activating protein 1
K08053 RASA2, GAP1M; Ras GTPase-activating protein 2
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05452 GDNF; glial cell derived neurotrophic factor
K25414 NRTN; neurturin
K25415 ARTN; artemin
K25416 PSPN; persephin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04370 LAMTOR3, MP1, MAP2K1IP1; ragulator complex protein LAMTOR3
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04372 MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04375 ELK1; ETS domain-containing protein Elk-1
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K04377 MYC; Myc proto-oncogene protein
K04378 SRF; serum response factor
K04379 FOS; proto-oncogene protein c-fos
K04380 MAPT, TAU; microtubule-associated protein tau
K04381 STMN1; stathmin 1
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K04391 CD14; monocyte differentiation antigen CD14
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K02308 DAXX; death-associated protein 6
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04405 ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
K04406 MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
K04407 MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
K04408 MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K04411 STK4, MST1; serine/threonine kinase 4
K04412 STK3, MST2; serine/threonine kinase 3
K04414 MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04419 MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
K04420 MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04417 MAP3K9, MLK1; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
K04418 MAP3K10, MLK2; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K17534 MLK4, KIAA1804; mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]
K04423 MAP3K12, MUK; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
K04422 MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
K04424 ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
K04425 MAP3K6, ASK2; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04428 MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04434 MAPK8IP1, JIP1; mitogen-activated protein kinase 8 interacting protein 1
K04435 MAPK8IP2, JIP2; mitogen-activated protein kinase 8 interacting protein 2
K04436 MAPK8IP3, JIP3; mitogen-activated protein kinase 8 interacting protein 3
K04437 FLNA; filamin-A
K04438 CRK, CRKII; C-crk adapter molecule crk
K04439 ARRB; beta-arrestin
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04442 MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K16510 RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K04448 JUN; transcription factor AP-1
K04449 JUND; transcription factor jun-D
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04451 TP53, P53; tumor protein p53
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K04453 MAX; Max protein
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K04455 HSPB1; heat shock protein beta-1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04457 PPM1A, PP2CA; protein phosphatase 1A [EC:3.1.3.16]
K04458 PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
K18018 PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
K18019 PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K04459 DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
K21946 DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
K18498 DUSP9, MKP4; dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
K20216 DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
K17614 DUSP3, VHR; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
K04460 PPP5C; serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
K04461 PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K09253 RELB; transcription factor RelB
|
04013 MAPK signaling pathway - fly [PATH:ko04013]
|
04016 MAPK signaling pathway - plant [PATH:ko04016]
|
04011 MAPK signaling pathway - yeast [PATH:ko04011]
|
04012 ErbB signaling pathway [PATH:ko04012]
|
04014 Ras signaling pathway [PATH:ko04014]
|
04015 Rap1 signaling pathway [PATH:ko04015]
|
04310 Wnt signaling pathway [PATH:ko04310]
|
04330 Notch signaling pathway [PATH:ko04330]
|
04340 Hedgehog signaling pathway [PATH:ko04340]
|
04341 Hedgehog signaling pathway - fly [PATH:ko04341]
|
04350 TGF-beta signaling pathway [PATH:ko04350]
|
04390 Hippo signaling pathway [PATH:ko04390]
|
04391 Hippo signaling pathway - fly [PATH:ko04391]
|
04392 Hippo signaling pathway - multiple species [PATH:ko04392]
|
04370 VEGF signaling pathway [PATH:ko04370]
|
04371 Apelin signaling pathway [PATH:ko04371]
|
04630 JAK-STAT signaling pathway [PATH:ko04630]
|
04064 NF-kappa B signaling pathway [PATH:ko04064]
|
04668 TNF signaling pathway [PATH:ko04668]
|
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K09558 BAG4; BCL2-associated athanogene 4
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K05632 ITCH, AIP4; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K16510 RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K15637 PGAM5; serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K14625 CCL20; C-C motif chemokine 20
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K06052 JAG1, CD339; jagged-1
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05433 IL15; interleukin 15
K05419 LIF; leukemia inhibitory factor
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K09258 BCL3; B-cell CLL/lymphoma 3 protein
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K03172 TRAF1; TNF receptor-associated factor 1
K17072 IFI47; interferon gamma inducible protein 47
K09028 JUNB; transcription factor jun-B
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K07763 MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
K16366 EDN1; endothelin-1
K05449 VEGFC_D; vascular endothelial growth factor C/D
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K06494 SELE, CD62E; selectin, endothelial cell
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K03174 TRAF3; TNF receptor-associated factor 3
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K19901 DAB2IP, AIP1; disabled homolog 2-interacting protein
K09444 IRF1; interferon regulatory factor 1
K05415 IFNB; interferon beta
|
04066 HIF-1 signaling pathway [PATH:ko04066]
|
04068 FoxO signaling pathway [PATH:ko04068]
|
04020 Calcium signaling pathway [PATH:ko04020]
|
04070 Phosphatidylinositol signaling system [PATH:ko04070]
|
04072 Phospholipase D signaling pathway [PATH:ko04072]
|
04071 Sphingolipid signaling pathway [PATH:ko04071]
|
04024 cAMP signaling pathway [PATH:ko04024]
|
04022 cGMP-PKG signaling pathway [PATH:ko04022]
|
K04166 AGTR1; angiotensin II receptor type 1
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04135 ADRA1A; adrenergic receptor alpha-1A
K04136 ADRA1B; adrenergic receptor alpha-1B
K04137 ADRA1D; adrenergic receptor alpha-1D
K04138 ADRA2A; adrenergic receptor alpha-2A
K04139 ADRA2B; adrenergic receptor alpha-2B
K04140 ADRA2C; adrenergic receptor alpha-2C
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K04969 TRPC6; transient receptor potential cation channel subfamily C member 6
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K09261 MEF2B; MADS-box transcription enhancer factor 2B
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K09262 MEF2D; MADS-box transcription enhancer factor 2D
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K04378 SRF; serum response factor
K09183 GATA4; GATA-binding protein 4
K17751 MYH6_7; myosin heavy chain 6/7
K12335 NPPB; natriuretic peptide B
K12334 NPPA; natriuretic peptide A
K12323 ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12336 NPPC; natriuretic peptide C
K12324 ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
K19477 PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04936 KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1
K05274 KCNMA3, KCNU1, KCA5.1; potassium large conductance calcium-activated channel subfamily M alpha member 3
K04937 KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
K04938 KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
K04939 KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
K04941 KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
K05849 SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540 ATP1B, CD298; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K18154 RGS2; regulator of G-protein signaling 2
K03121 TFII-I, GTF2I; transcription initiation factor TFII-I
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K12337 MRVI1, IRAG; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
K05852 PLN; phospholamban
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K02183 CALM; calmodulin
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K12755 MYL9; myosin regulatory light chain 9
K04948 CNGA1; cyclic nucleotide gated channel alpha 1
K04952 CNGB1; cyclic nucleotide gated channel beta 1
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K18283 PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
K19021 PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K13762 PDE5; cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K03898 KNG, BK; kininogen
K03916 BDKRB2; bradykinin receptor B2
K04213 OPRD1; delta-type opioid receptor
K04265 ADORA1; adenosine receptor A1
K04268 ADORA3; adenosine receptor A3
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04526 INS; insulin
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K04141 ADRB1; adrenergic receptor beta-1
K04142 ADRB2; adrenergic receptor beta-2
K04143 ADRB3; adrenergic receptor beta-3
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K05001 KCNJ8, KIR6.1; potassium inwardly-rectifying channel subfamily J member 8
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K02158 BAD; Bcl-2-antagonist of cell death
K06274 VASP; vasodilator-stimulated phosphoprotein
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
|
04151 PI3K-Akt signaling pathway [PATH:ko04151]
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05452 GDNF; glial cell derived neurotrophic factor
K25414 NRTN; neurturin
K25415 ARTN; artemin
K25416 PSPN; persephin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16172 IRS1; insulin receptor substrate 1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K06465 CD19; B-lymphocyte antigen CD19
K12230 PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
K05438 GH; growth hormone
K05439 PRL; prolactin
K05418 OSM; oncostatin M
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05405 IL6; interleukin 6
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05437 EPO; erythropoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05057 OSMR; oncostatin M receptor
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05071 IL4R, CD124; interleukin 4 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05079 EPOR; erythropoietin receptor
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K06493 ITGB3, CD61; integrin beta 3
K06525 ITGB4, CD104; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K08266 MLST8, GBL; target of rapamycin complex subunit LST8
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K23692 PKN3; serine/threonine-protein kinase N3 [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05631 AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K05629 AIP1; atrophin-1 interacting protein 1
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K16339 THEM4, CTMP; acyl-coenzyme A thioesterase THEM4 [EC:3.1.2.2]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K09554 CDC37; cell division cycle protein 37
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K10167 TCL1A; T-cell leukemia/lymphoma 1A
K16836 TCL1B; T-cell leukemia/lymphoma 1B
K16837 MTCP1; mature T-cell proliferation-1 type B1
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K01596 E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06626 CCNE; G1/S-specific cyclin-E1
K09408 FOXO3; forkhead box protein O3
K16332 RBL2; retinoblastoma-like protein 2
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K08524 RXRA, NR2B1; retinoid X receptor alpha
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K09420 MYB, C-MYB; transcriptional activator Myb
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
|
04152 AMPK signaling pathway [PATH:ko04152]
|
04150 mTOR signaling pathway [PATH:ko04150]
|
04075 Plant hormone signal transduction [PATH:ko04075]
|
|
09133 Signaling molecules and interaction
|
|
09140 Cellular Processes
|
|
09141 Transport and catabolism
|
04144 Endocytosis [PATH:ko04144]
|
04145 Phagosome [PATH:ko04145]
|
04142 Lysosome [PATH:ko04142]
|
04146 Peroxisome [PATH:ko04146]
|
04140 Autophagy - animal [PATH:ko04140]
|
04138 Autophagy - yeast [PATH:ko04138]
|
04136 Autophagy - other [PATH:ko04136]
|
04137 Mitophagy - animal [PATH:ko04137]
|
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
K17771 TOM7; mitochondrial import receptor subunit TOM7
K11518 TOM40; mitochondrial import receptor subunit TOM40
K17770 TOM20; mitochondrial import receptor subunit TOM20
K17768 TOM70; mitochondrial import receptor subunit TOM70
K04556 PARK2; parkin [EC:2.3.2.31]
K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K10636 AMFR, GP78; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
K10592 HUWE1, MULE, ARF-BP1, TOM1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
K06030 MFN2, FZO1; mitofusin 2 [EC:3.6.5.-]
K07870 RHOT1, ARHT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
K07871 RHOT2, ARHT2; mitochondrial Rho GTPase 2 [EC:3.6.5.-]
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K21347 TAX1BP1; Tax1-binding protein 1
K14381 SQSTM1; sequestosome 1
K21348 CALCOCO2, NDP52; calcium-binding and coiled-coil domain-containing protein 2
K19946 OPTN, FIP2; optineurin
K17987 NBR1; next to BRCA1 gene 1 protein
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
K10435 MAP1LC; microtubule-associated protein 1 light chain
K08334 BECN, VPS30, ATG6; beclin
K11839 USP8, UBP5; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
K21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]
K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K15637 PGAM5; serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K17986 FUNDC1; FUN14 domain-containing protein 1
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K15465 BNIP3L; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
K15485 BCL2L13, BCL-RAMBO; Bcl-2-like protein 13
K09574 FKBP8; FK506-binding protein 8 [EC:5.2.1.8]
K07277 SAM50, TOB55, bamA; outer membrane protein insertion porin family
K17081 PHB2; prohibitin 2
K12653 NLRX1; NLR family member X1
K17776 MTX; metaxin
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04735 RELA; transcription factor p65
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K17454 E2F1; transcription factor E2F1
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04684 SP1; transcription factor Sp1
K04451 TP53, P53; tumor protein p53
K09408 FOXO3; forkhead box protein O3
K21361 CITED2; Cbp/p300-interacting transactivator 2
K09455 MITF; microphthalmia-associated transcription factor
K15590 TFEB; transcription factor EB
K09105 TFE3; transcription factor E3
K20131 RABGEF1; Rab5 GDP/GTP exchange factor
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K20195 MON1; vacuolar fusion protein MON1
K27045 CCZ1; vacuolar fusion protein CCZ1, animal type
K07897 RAB7A; Ras-related protein Rab-7A
K07898 RAB7B; Ras-related protein Rab-7B
K20168 TBC1D15; TBC1 domain family member 15
K19945 TBC1D17; TBC1 domain family member 17
K17969 FIS1, TTC11, MDV2; mitochondrial fission 1 protein
K17907 ATG9; autophagy-related protein 9
K17079 OPA1; optic atrophy protein 1 [EC:3.6.5.5]
K13525 VCP, CDC48; transitional endoplasmic reticulum ATPase
|
04139 Mitophagy - yeast [PATH:ko04139]
|
04148 Efferocytosis [PATH:ko04148]
|
|
09143 Cell growth and death
|
04110 Cell cycle [PATH:ko04110]
|
04111 Cell cycle - yeast [PATH:ko04111]
|
04112 Cell cycle - Caulobacter [PATH:ko04112]
|
04113 Meiosis - yeast [PATH:ko04113]
|
04114 Oocyte meiosis [PATH:ko04114]
|
04210 Apoptosis [PATH:ko04210]
|
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04396 CASP6; caspase 6 [EC:3.4.22.59]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10522 DIABLO, SMAC; diablo
K16943 SEPT4; septin 4
K08669 HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K07374 TUBA; tubulin alpha
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K05692 ACTB_G1; actin beta/gamma 1
K06114 SPTAN; spectrin alpha, non-erythrocytic (fodrin)
K12641 LMNA; lamin A/C
K07611 LMNB; lamin B
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K02310 DFFA, DFF45; DNA fragmentation factor, 45 kD, alpha subunit
K02311 DFFB, DFF40; DNA fragmentation factor, 40 kD, beta subunit [EC:3.-.-.-]
K01173 ENDOG; endonuclease G, mitochondrial
K04727 AIFM1, PDCD8; apoptosis-inducing factor 1 [EC:1.-.-.-]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K01275 CTSC; cathepsin C [EC:3.4.14.1]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K01373 CTSF; cathepsin F [EC:3.4.22.41]
K01366 CTSH; cathepsin H [EC:3.4.22.16]
K01371 CTSK; cathepsin K [EC:3.4.22.38]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01374 CTSO; cathepsin O [EC:3.4.22.42]
K01368 CTSS; cathepsin S [EC:3.4.22.27]
K01375 CTSL2, CTSV; cathepsin V [EC:3.4.22.43]
K08569 CTSW; cathepsin W [EC:3.4.22.-]
K08568 CTSZ; cathepsin X [EC:3.4.18.1]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K02308 DAXX; death-associated protein 6
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K19901 DAB2IP, AIP1; disabled homolog 2-interacting protein
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K04451 TP53, P53; tumor protein p53
K02512 HRK; activator of apoptosis harakiri
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02374 PTPN13, FAP-1; tyrosine-protein phosphatase non-receptor type 13
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K03172 TRAF1; TNF receptor-associated factor 1
K02162 BCL2A1; hematopoietic Bcl-2-related protein A1
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K10130 LRDD, PIDD; leucine-rich repeats and death domain-containing protein
K13773 TP53AIP1; p53-regulated apoptosis-inducing protein 1
K10132 BBC3, PUMA; Bcl-2-binding component 3
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K02186 CASP2; caspase 2 [EC:3.4.22.55]
K02582 NGFB; nerve growth factor, beta
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04736 IL3; interleukin 3
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
|
04214 Apoptosis - fly [PATH:ko04214]
|
K14034 NR1H1, EcR; ecdysone receptor
K14030 NR2B4, usp; nuclear receptor subfamily 2 group B member 4
K20014 RPR; cell death protein rpr
K20009 DRONC; caspase Dronc [EC:3.4.22.-]
K09428 ELF1_2_4; E74-like factor 1/2/4
K02174 BR-C; broad-complex core protein
K20015 EIP93F; ecdysone-induced protein 93F, isoform B
K20016 HID; cell death protein hid
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02084 APAF1; apoptotic protease-activating factor
K20010 STRICA; Ser/Thr-rich caspase [EC:3.4.22.-]
K02561 BOK; Bcl-2-related ovarian killer protein
K20017 BUFFY; Bcl-2 family protein
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
K06030 MFN2, FZO1; mitofusin 2 [EC:3.6.5.-]
K08738 CYC; cytochrome c
K05770 TSPO, BZRP; translocator protein
K04727 AIFM1, PDCD8; apoptosis-inducing factor 1 [EC:1.-.-.-]
K07870 RHOT1, ARHT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
K10586 BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
K03386 PRDX2_4, ahpC; peroxiredoxin 2/4 [EC:1.11.1.24]
K20018 GRIM; cell death protein Grim
K20019 SKL; IAP-inhibitory protein Sickle
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K08669 HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K20008 DCP1; death caspase-1 [EC:3.4.22.-]
K01527 EGD1, BTF3; nascent polypeptide-associated complex subunit beta
K03262 EIF5; translation initiation factor 5
K07611 LMNB; lamin B
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K16736 BAN; bantam
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K07827 KRAS, KRAS2; GTPase KRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04412 STK3, MST2; serine/threonine kinase 3
K16686 SAV1, Sav; scaffold protein salvador
K08791 LATS1_2, Wts; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K09848 TRAF4; TNF receptor-associated factor 4
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K16678 EGR; eiger
K16679 WGN; wengen
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K09031 FOSLN; fos-like antigen, invertebrate
K20216 DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K10149 TP63; tumor protein p63
|
04215 Apoptosis - multiple species [PATH:ko04215]
|
04216 Ferroptosis [PATH:ko04216]
|
04217 Necroptosis [PATH:ko04217]
|
04115 p53 signaling pathway [PATH:ko04115]
|
04218 Cellular senescence [PATH:ko04218]
|
|
09144 Cellular community - eukaryotes
|
|
09145 Cellular community - prokaryotes
|
|
09142 Cell motility
|
|
09150 Organismal Systems
|
|
09151 Immune system
|
|
09152 Endocrine system
|
04911 Insulin secretion [PATH:ko04911]
|
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07593 SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K12407 GCK; glucokinase [EC:2.7.1.2]
K04979 TRPM4; transient receptor potential cation channel subfamily M member 4
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540 ATP1B, CD298; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K05032 ABCC8, SUR1; ATP-binding cassette subfamily C (CFTR/MRP) member 8
K05004 KCNJ11, KIR6.2; potassium inwardly-rectifying channel subfamily J member 11
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04936 KCNMA1, KCA1.1; potassium large conductance calcium-activated channel subfamily M alpha member 1
K05274 KCNMA3, KCNU1, KCA5.1; potassium large conductance calcium-activated channel subfamily M alpha member 3
K04937 KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
K04938 KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
K04939 KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
K04941 KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
K04942 KCNN1, KCA2.1; potassium intermediate/small conductance calcium-activated channel subfamily N member 1
K04943 KCNN2, KCA2.2; potassium intermediate/small conductance calcium-activated channel subfamily N member 2
K04944 KCNN3, KCA2.3; potassium intermediate/small conductance calcium-activated channel subfamily N member 3
K04945 KCNN4, KCA3.1; potassium intermediate/small conductance calcium-activated channel subfamily N member 4
K05259 GCG; glucagon
K04581 GLP1R; glucagon-like peptide 1 receptor
K05258 GIP; gastric inhibitory polypeptide
K08424 GPR119; glucose-dependent insulinotropic receptor
K05262 ADCYAP; pituitary adenylate cyclase-activating polypeptide
K04587 ADCYAP1R1, PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K07594 IPF1, PDX1; insulin promoter factor 1
K04526 INS; insulin
K04351 RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
K15297 RIMS2, RIM2; regulating synaptic membrane exocytosis protein 2
K16882 PCLO; protein piccolo
K07882 RAB3A; Ras-related protein Rab-3A
K05226 CCK; cholecystokinin
K04194 CCKAR; cholecystokinin A receptor
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04325 FFAR1, GPR40; free fatty acid receptor 1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04962 RYR2; ryanodine receptor 2
K13504 VAMP2; vesicle-associated membrane protein 2
K04560 STX1A; syntaxin 1A
K18211 SNAP25; synaptosomal-associated protein 25
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
|
04910 Insulin signaling pathway [PATH:ko04910]
|
04922 Glucagon signaling pathway [PATH:ko04922]
|
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K05259 GCG; glucagon
K04583 GCGR; glucagon receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K17491 SMEK, PPP4R3; protein phosphatase 4 regulatory subunit 3
K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16311 SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K07202 PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K19008 SIK1; serine/threonine-protein kinase SIK1 [EC:2.7.11.1]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K07201 FOXO1; forkhead box protein O1
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01596 E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K02183 CALM; calmodulin
K00688 PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]
K19028 PFKFB1; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07593 SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K12407 GCK; glucokinase [EC:2.7.1.2]
K03841 FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K00850 pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
K01834 PGAM, gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K00873 PK, pyk; pyruvate kinase [EC:2.7.1.40]
K00161 PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB, pdhB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
K00016 LDH, ldh; L-lactate dehydrogenase [EC:1.1.1.27]
|
04923 Regulation of lipolysis in adipocytes [PATH:ko04923]
|
04920 Adipocytokine signaling pathway [PATH:ko04920]
|
03320 PPAR signaling pathway [PATH:ko03320]
|
04929 GnRH secretion [PATH:ko04929]
|
04912 GnRH signaling pathway [PATH:ko04912]
|
K05252 GNRH; gonadotropin-releasing hormone
K04280 GNRHR; gonadotropin-releasing hormone receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04420 MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04428 MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04393 CDC42; cell division control protein 42
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K08521 LHB; lutropin subunit beta
K08522 CGA; glycoprotein hormones alpha chain
K05250 FSHB; follitropin subunit beta
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K07763 MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
K08523 HBEGF; heparin-binding EGF-like growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K09203 EGR1; early growth response protein 1
|
04913 Ovarian steroidogenesis [PATH:ko04913]
|
04915 Estrogen signaling pathway [PATH:ko04915]
|
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K09101 NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11255 NCOA2, TIF2, KAT13C; nuclear receptor coactivator 2
K11256 NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
K02161 BCL2; apoptosis regulator Bcl-2
K22455 EBAG9; estrogen receptor-binding fragment-associated gene 9 protein
K07604 KRT1; type I keratin, acidic
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K27477 GREB1; growth regulating estrogen receptor binding 1
K22456 TFF1; trefoil factor 1
K08556 PGR, NR3C3; progesterone receptor
K08774 TGFA; transforming growth factor, alpha
K08527 RARA, NR1B1; retinoic acid receptor alpha
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04684 SP1; transcription factor Sp1
K04246 GPER1, GPR30; G-protein coupled estrogen receptor 1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K08523 HBEGF; heparin-binding EGF-like growth factor
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04615 GABBR; gamma-aminobutyric acid type B receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04997 KCNJ3, KIR3.1; potassium inwardly-rectifying channel subfamily J member 3
K05000 KCNJ6, KIR3.2; potassium inwardly-rectifying channel subfamily J member 6
K05002 KCNJ9, KIR3.3; potassium inwardly-rectifying channel subfamily J member 9
K04999 KCNJ5, KIR3.4; potassium inwardly-rectifying channel subfamily J member 5
K05228 POMC; proopiomelanocortin
K04215 OPRM1; mu-type opioid receptor
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K04603 GRM1; metabotropic glutamate receptor 1
|
04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
|
04917 Prolactin signaling pathway [PATH:ko04917]
|
04921 Oxytocin signaling pathway [PATH:ko04921]
|
04926 Relaxin signaling pathway [PATH:ko04926]
|
K21998 RLN1_2; relaxin 1/2
K04306 RXFP1, LGR7; relaxin family peptide receptor 1
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K05449 VEGFC_D; vascular endothelial growth factor C/D
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K16366 EDN1; endothelin-1
K04198 EDNRB; endothelin receptor type B
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
K13375 TGFB1; transforming growth factor beta-1
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K12313 ACTA2; actin, aortic smooth muscle
K06236 COL1A; collagen type I alpha
K19720 COL3A; collagen type III alpha
K06237 COL4A; collagen type IV alpha
K21999 INSL3; insulin-like 3
K04307 RXFP2, LGR8; relaxin family peptide receptor 2
K22000 RLN3; relaxin 3
K08397 RXFP3, RLN3R1; relaxin family peptide receptor 3
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K03099 SOS; son of sevenless
K04439 ARRB; beta-arrestin
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K22001 INSL5; insulin-like 5
K08398 RXFP4, RLN3R2; relaxin family peptide receptor 4
K04637 GNA15; guanine nucleotide-binding protein subunit alpha-15
|
04935 Growth hormone synthesis, secretion and action [PATH:ko04935]
|
K05260 GHRH; growth hormone-releasing hormone
K04584 GHRHR; growth hormone releasing hormone receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K05237 SST; somatostatin
K04217 SSTR1; somatostatin receptor 1
K04218 SSTR2; somatostatin receptor 2
K04219 SSTR3; somatostatin receptor 3
K04221 SSTR5; somatostatin receptor 5
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K09363 POU1F, PIT1; POU domain transcription factor, class 1
K04379 FOS; proto-oncogene protein c-fos
K05438 GH; growth hormone
K05254 GHRL; ghrelin
K04284 GHSR; growth hormone secretagogue receptor
K25968 MRAP2; melanocortin-2 receptor accessory protein 2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K05080 GHR; growth hormone receptor
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K11220 STAT1; signal transducer and activator of transcription 1
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05459 IGF1; insulin-like growth factor 1
K09028 JUNB; transcription factor jun-B
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K04695 SOCS2, CIS2; suppressor of cytokine signaling 2
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K17256 IGFALS, ALS; insulin-like growth factor-binding protein complex acid labile subunit
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
|
04918 Thyroid hormone synthesis [PATH:ko04918]
|
K05251 TSHB; thyrotropin subunit beta
K08522 CGA; glycoprotein hormones alpha chain
K04249 TSHR; thyrotropin receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K15225 TTF1; transcription termination factor 1
K15173 TTF2; transcription termination factor 2 [EC:5.6.2.-]
K09293 PAX8; paired box protein 8
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K10809 TG; thyroglobulin
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K08054 CANX; calnexin
K09582 PDIA4, ERP72; protein disulfide-isomerase A4 [EC:5.3.4.1]
K10063 ASGR1; asialoglycoprotein receptor 1
K10064 ASGR2; asialoglycoprotein receptor 2
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K14385 SLC5A5, NIS; solute carrier family 5 (sodium/iodide cotransporter), member 5
K14702 SLC26A4, PDS; solute carrier family 26 (sodium-independent chloride/iodide transporter), member 4
K00431 TPO; thyroid peroxidase [EC:1.11.1.8]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540 ATP1B, CD298; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K17231 IYD, DEHAL1; iodotyrosine deiodinase [EC:1.21.1.1]
K17232 DUOXA2; dual oxidase maturation factor 2
K13411 DUOX, THOX; dual oxidase [EC:1.6.3.1 1.11.1.-]
K00432 gpx, btuE, bsaA; glutathione peroxidase [EC:1.11.1.9]
K00383 GSR, gor; glutathione reductase (NADPH) [EC:1.8.1.7]
K16141 ALB; serum albumin
K20731 TTR; transthyretin
K20734 SERPINA7, TBG; thyroxine-binding globulin
K06233 LRP2; low density lipoprotein-related protein 2
|
04919 Thyroid hormone signaling pathway [PATH:ko04919]
|
04928 Parathyroid hormone synthesis, secretion and action [PATH:ko04928]
|
K04612 CASR; calcium-sensing receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K21598 GCM; chorion-specific transcription factor GCM
K09036 MAFB; transcription factor MAFB
K17895 GATA3; GATA-binding protein 3
K04684 SP1; transcription factor Sp1
K08539 VDR, NR1I1; vitamin D3 receptor
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K14756 KL; klotho [EC:3.2.1.31]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K09203 EGR1; early growth response protein 1
K05261 PTH; parathyroid hormone
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K08867 WNK, PRKWNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
K08835 OXSR1, STK39; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
K14426 SLC12A3, TSC; solute carrier family 12 (sodium/chloride transporter), member 3
K22608 PTHLH, PTHRP; parathyroid hormone-related hormone
K04585 PTH1R, PTHR1; parathyroid hormone receptor 1
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04974 TRPV5; transient receptor potential cation channel subfamily V member 5
K14683 SLC34A, NPT, nptA; solute carrier family 34 (sodium-dependent phosphate cotransporter)
K13365 SLC9A3R1, NHERF1; sodium/hydrogen exchange regulatory cofactor NHE-RF1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K07438 CYP27B1; calcidiol 1-monooxygenase (25-hydroxyvitamin D3 1alpha-hydroxylase) [EC:1.14.15.18]
K07436 CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.15.16]
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K09262 MEF2D; MADS-box transcription enhancer factor 2D
K16834 SOST; sclerostin
K08558 NR4A2, NURR1; nuclear receptor subfamily 4 group A member 2
K03626 EGD2, NACA; nascent polypeptide-associated complex subunit alpha
K04449 JUND; transcription factor jun-D
K22609 BGLAP; osteocalcin
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K02161 BCL2; apoptosis regulator Bcl-2
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04379 FOS; proto-oncogene protein c-fos
K09278 RUNX2, AML3; runt-related transcription factor 2
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K16529 ARHGEF13; A-kinase anchor protein 13
K04513 RHOA; Ras homolog gene family, member A
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04439 ARRB; beta-arrestin
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K07763 MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
K07995 MMP15; matrix metalloproteinase-15 (membrane-inserted) [EC:3.4.24.-]
K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
K07997 MMP17; matrix metalloproteinase-17 (membrane-inserted) [EC:3.4.24.-]
K08002 MMP24; matrix metalloproteinase-24 (membrane-inserted) [EC:3.4.24.-]
K08003 MMP25; matrix metalloproteinase-25 (membrane-inserted) [EC:3.4.24.-]
K08523 HBEGF; heparin-binding EGF-like growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
|
04916 Melanogenesis [PATH:ko04916]
|
04924 Renin secretion [PATH:ko04924]
|
04614 Renin-angiotensin system [PATH:ko04614]
|
04925 Aldosterone synthesis and secretion [PATH:ko04925]
|
K09821 AGT, SERPINA8; angiotensinogen
K04166 AGTR1; angiotensin II receptor type 1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K09053 ATF1; activating transcription factor 1
K13806 DAGL; sn1-specific diacylglycerol lipase [EC:3.1.1.116]
K04914 KCNK3, K2P3.1; potassium channel subfamily K member 3
K04919 KCNK9, K2P9.1; potassium channel subfamily K member 9
K04999 KCNJ5, KIR3.4; potassium inwardly-rectifying channel subfamily J member 5
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540 ATP1B, CD298; sodium/potassium-transporting ATPase subunit beta
K04854 CACNA1G, CAV3.1; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H, CAV3.2; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I, CAV3.3; voltage-dependent calcium channel T type alpha-1I
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K16056 ORAI1; calcium release-activated calcium channel protein 1
K02183 CALM; calmodulin
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K07188 LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
K12473 LDLR; low-density lipoprotein receptor
K13885 SCARB1; scavenger receptor class B, member 1
K05228 POMC; proopiomelanocortin
K04200 MC2R; melanocortin 2 receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K07433 CYP11B2; steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
K16931 STAR; steroidogenic acute regulatory protein, mitochondrial
K08558 NR4A2, NURR1; nuclear receptor subfamily 4 group A member 2
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K12334 NPPA; natriuretic peptide A
K12323 ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K18283 PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
|
04927 Cortisol synthesis and secretion [PATH:ko04927]
|
K05228 POMC; proopiomelanocortin
K04200 MC2R; melanocortin 2 receptor
K22398 MRAP; melanocortin-2 receptor accessory protein
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08562 NR0B1, DAX1; nuclear receptor subfamily 0 group B member 1
K08560 NR5A1, SF1; steroidogenic factor 1
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K04684 SP1; transcription factor Sp1
K09355 PBX1; pre-B-cell leukemia transcription factor 1
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K16931 STAR; steroidogenic acute regulatory protein, mitochondrial
K14349 NCEH1, AADACL1; neutral cholesterol ester hydrolase 1 [EC:3.1.1.-]
K09821 AGT, SERPINA8; angiotensinogen
K04166 AGTR1; angiotensin II receptor type 1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04913 KCNK2, K2P2.1; potassium channel subfamily K member 2
K04854 CACNA1G, CAV3.1; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H, CAV3.2; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I, CAV3.3; voltage-dependent calcium channel T type alpha-1I
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K16056 ORAI1; calcium release-activated calcium channel protein 1
K04877 KCNA4, KV1.4; potassium voltage-gated channel Shaker-related subfamily A member 4
K04914 KCNK3, K2P3.1; potassium channel subfamily K member 3
K12473 LDLR; low-density lipoprotein receptor
K13885 SCARB1; scavenger receptor class B, member 1
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
|
|
09153 Circulatory system
|
04260 Cardiac muscle contraction [PATH:ko04260]
|
04261 Adrenergic signaling in cardiomyocytes [PATH:ko04261]
|
K04141 ADRB1; adrenergic receptor beta-1
K04142 ADRB2; adrenergic receptor beta-2
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K21108 BVES, POPDC1; blood vessel epicardial substance
K26206 POPDC2; popeye domain-containing protein 2
K26207 POPDC3; popeye domain-containing protein 3
K04913 KCNK2, K2P2.1; potassium channel subfamily K member 2
K04345 PKA; protein kinase A [EC:2.7.11.11]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540 ATP1B, CD298; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K04926 KCNQ1, KV7.1; potassium voltage-gated channel KQT-like subfamily member 1
K04894 KCNE1; potassium voltage-gated channel Isk-related subfamily E member 1
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05849 SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
K04838 SCN5A, NAV1.5; voltage-gated sodium channel type V alpha
K04839 SCN7A, SCN6A; voltage-gated sodium channel type VII alpha
K04845 SCN1B; voltage-gated sodium channel type I beta
K04848 SCN4B; voltage-gated sodium channel type IV beta
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04862 CACNB1; voltage-dependent calcium channel beta-1
K04863 CACNB2; voltage-dependent calcium channel beta-2
K04864 CACNB3; voltage-dependent calcium channel beta-3
K04865 CACNB4; voltage-dependent calcium channel beta-4
K04858 CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
K04859 CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
K04860 CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
K04861 CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
K04866 CACNG1; voltage-dependent calcium channel gamma-1
K04867 CACNG2; voltage-dependent calcium channel gamma-2
K04868 CACNG3; voltage-dependent calcium channel gamma-3
K04869 CACNG4; voltage-dependent calcium channel gamma-4
K04870 CACNG5; voltage-dependent calcium channel gamma-5
K04871 CACNG6; voltage-dependent calcium channel gamma-6
K04872 CACNG7; voltage-dependent calcium channel gamma-7
K04873 CACNG8; voltage-dependent calcium channel gamma-8
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04962 RYR2; ryanodine receptor 2
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K05865 TNNC1; troponin C, slow skeletal and cardiac muscles
K12044 TNNI3; troponin I, cardiac muscle
K12045 TNNT2; troponin T, cardiac muscle
K10373 TPM1; tropomyosin 1
K10374 TPM2; tropomyosin 2
K09290 TPM3; tropomyosin 3
K10375 TPM4; tropomyosin 4
K12314 ACTC1; actin, alpha cardiac muscle
K17751 MYH6_7; myosin heavy chain 6/7
K10351 MYL2; myosin regulatory light chain 2
K12749 MYL3; myosin light chain 3
K12750 MYL4; myosin light chain 4
K05852 PLN; phospholamban
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K09821 AGT, SERPINA8; angiotensinogen
K04166 AGTR1; angiotensin II receptor type 1
K04167 AGTR2; angiotensin II receptor type 2
K04135 ADRA1A; adrenergic receptor alpha-1A
K04136 ADRA1B; adrenergic receptor alpha-1B
K04137 ADRA1D; adrenergic receptor alpha-1D
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K08050 PPP1R1A; protein phosphatase 1 regulatory subunit 1A
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K09052 CREM; cAMP response element modulator
K02161 BCL2; apoptosis regulator Bcl-2
K08014 RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
|
04270 Vascular smooth muscle contraction [PATH:ko04270]
|
|
09154 Digestive system
|
|
09155 Excretory system
|
|
09156 Nervous system
|
04724 Glutamatergic synapse [PATH:ko04724]
|
04727 GABAergic synapse [PATH:ko04727]
|
04725 Cholinergic synapse [PATH:ko04725]
|
K00623 CHAT; choline O-acetyltransferase [EC:2.3.1.6]
K01049 ACHE; acetylcholinesterase [EC:3.1.1.7]
K14636 SLC18A3, VACHT; MFS transporter, DHA1 family, solute carrier family 18 (vesicular acetylcholine transporter), member 3
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04133 CHRM5; muscarinic acetylcholine receptor M5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04926 KCNQ1, KV7.1; potassium voltage-gated channel KQT-like subfamily member 1
K04927 KCNQ2, KV7.2; potassium voltage-gated channel KQT-like subfamily member 2
K04928 KCNQ3, KV7.3; potassium voltage-gated channel KQT-like subfamily member 3
K04929 KCNQ4, KV7.4; potassium voltage-gated channel KQT-like subfamily member 4
K04930 KCNQ5, KV7.5; potassium voltage-gated channel KQT-like subfamily member 5
K04996 KCNJ2, KIR2.1; potassium inwardly-rectifying channel subfamily J member 2
K05005 KCNJ12_18, KIR2.2, KIR2.6; potassium inwardly-rectifying channel subfamily J member 12/18
K04998 KCNJ4, KIR2.3; potassium inwardly-rectifying channel subfamily J member 4
K05007 KCNJ14, KIR2.4; potassium inwardly-rectifying channel subfamily J member 14
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04132 CHRM4; muscarinic acetylcholine receptor M4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04997 KCNJ3, KIR3.1; potassium inwardly-rectifying channel subfamily J member 3
K05000 KCNJ6, KIR3.2; potassium inwardly-rectifying channel subfamily J member 6
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K04806 CHRNA4; nicotinic acetylcholine receptor alpha-4
K04813 CHRNB2; nicotinic acetylcholine receptor beta-2
K04805 CHRNA3; nicotinic acetylcholine receptor alpha-3
K04815 CHRNB4; nicotinic acetylcholine receptor beta-4
K04808 CHRNA6; nicotinic acetylcholine receptor alpha-6
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator Bcl-2
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K14387 SLC5A7, CHT1; solute carrier family 5 (high affinity choline transporter), member 7
|
04728 Dopaminergic synapse [PATH:ko04728]
|
K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K01593 DDC, TDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
K08155 SLC18A1_2, VMAT; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K04144 DRD1; dopamine receptor D1
K05840 DRD5; dopamine receptor D5
K15493 CALY; neuron-specific vesicular protein calcyon
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04379 FOS; proto-oncogene protein c-fos
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K15494 PPP1R1B, DARPP32; protein phosphatase 1 regulatory subunit 1B
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04833 SCN1A, NAV1.1; voltage-gated sodium channel type I alpha
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04997 KCNJ3, KIR3.1; potassium inwardly-rectifying channel subfamily J member 3
K05000 KCNJ6, KIR3.2; potassium inwardly-rectifying channel subfamily J member 6
K05002 KCNJ9, KIR3.3; potassium inwardly-rectifying channel subfamily J member 9
K04999 KCNJ5, KIR3.4; potassium inwardly-rectifying channel subfamily J member 5
K04146 DRD3; dopamine receptor D3
K04147 DRD4; dopamine receptor D4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04145 DRD2; dopamine receptor D2
K04439 ARRB; beta-arrestin
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K10396 KIF5; kinesin family member 5
K02223 CLOCK, KAT13D; circadian locomoter output cycles kaput protein [EC:2.3.1.48]
K02296 ARNTL, BMAL1, CYC; aryl hydrocarbon receptor nuclear translocator-like protein 1
K05036 SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K00274 MAO, aofH; monoamine oxidase [EC:1.4.3.4]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
|
04726 Serotonergic synapse [PATH:ko04726]
|
04720 Long-term potentiation [PATH:ko04720]
|
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08050 PPP1R1A; protein phosphatase 1 regulatory subunit 1A
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08014 RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K02183 CALM; calmodulin
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
|
04730 Long-term depression [PATH:ko04730]
|
04723 Retrograde endocannabinoid signaling [PATH:ko04723]
|
04721 Synaptic vesicle cycle [PATH:ko04721]
|
04722 Neurotrophin signaling pathway [PATH:ko04722]
|
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K12457 NTF4; neurotrophin 4
K04356 NTF3; neurotrophin 3
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K05101 NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
K07193 SH2B, APS; SH2B adapter protein 2
K12459 SH2B1_3; SH2B adaptor protein 1/3
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K02161 BCL2; apoptosis regulator Bcl-2
K12460 KIDINS220, ARMS; ankyrin repeat-rich membrane spanning protein
K12461 FRS2; fibroblast growth factor receptor substrate 2
K04438 CRK, CRKII; C-crk adapter molecule crk
K06277 RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K09593 GAB1; GRB2-associated-binding protein 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K09408 FOXO3; forkhead box protein O3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K16172 IRS1; insulin receptor substrate 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K08888 MATK; megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K12462 ARHGDI, RHOGDI; Rho GDP-dissociation inhibitor
K04513 RHOA; Ras homolog gene family, member A
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04451 TP53, P53; tumor protein p53
K02159 BAX; apoptosis regulator BAX
K10148 TP73; tumor protein p73
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K12458 ZNF274; zinc finger protein 274
K12463 PRDM4; PR domain zinc finger protein 4 [EC:2.1.1.-]
K12464 MAGED1, NRAGE; melanoma-associated antigen D1
K12465 NGFRAP1; nerve growth factor receptor-associated protein 1
K06630 YWHAE; 14-3-3 protein epsilon
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
K04732 IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K12388 SORT1; sortilin
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2, PS2; presenilin 2 [EC:3.4.23.-]
|
|
09157 Sensory system
|
|
09158 Development and regeneration
|
|
09149 Aging
|
04211 Longevity regulating pathway [PATH:ko04211]
|
K04526 INS; insulin
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K08339 ATG5; autophagy-related protein 5
K14756 KL; klotho [EC:3.2.1.31]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1, PRAS40; proline-rich AKT1 substrate 1
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08331 ATG13; autophagy-related protein 13
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K19730 ATG101; autophagy-related protein 101
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K07296 ADIPOQ, ACDC; adiponectin
K07297 ADIPOR; adiponectin receptor
K08733 APPL1, DIP13A; DCC-interacting protein 13 alpha
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K02159 BAX; apoptosis regulator BAX
K04451 TP53, P53; tumor protein p53
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K07202 PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
|
04212 Longevity regulating pathway - worm [PATH:ko04212]
|
K19763 JKK1; dual specificity mitogen-activated protein kinase kinase JKK-1 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K19764 INS7; insulin-like neuropeptide
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K09408 FOXO3; forkhead box protein O3
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K27390 HCFC2; host cell factor 2
K17491 SMEK, PPP4R3; protein phosphatase 4 regulatory subunit 3
K14739 MT1_2; metallothionein 1/2
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K19765 HSBP1; heat shock factor-binding protein 1
K18463 CCDC53; WASH complex subunit CCDC53
K18461 WASH1; WAS protein family homolog 1
K09414 HSF1; heat shock transcription factor 1
K19766 HSP16.1; heat shock protein Hsp-16.1/Hsp-16.11
K19767 HSP16.49; heat shock protein Hsp-16.48/Hsp-16.49
K19768 HSP12.6; heat shock protein 12.6
K19769 SIP1; stress-induced protein 1
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K11204 GCLC; glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K08035 FOXA2, HNF3B; forkhead box protein A2, hepatocyte nuclear factor 3-beta
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K19770 RNASEK; ribonuclease kappa [EC:3.1.-.-]
K12824 TCERG1, CA150; transcription elongation regulator 1
K17705 KRIT1, CCM1; Krev interaction trapped protein 1
K19771 LIPL4; lipase
K19772 LIPS17; triacylglycerol lipase
K14938 NVD, DAF36; cholesterol 7-desaturase [EC:1.14.19.21]
K22878 DAF9; cytochrome P450 daf-9 [EC:1.14.15.15]
K14035 NR1IN; nuclear receptor subfamily 1 group I
K13356 FAR; alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]
K19773 NHR80; nuclear hormone receptor family member NHR-80
K00507 SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K01358 clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
K19762 HAF1; ATP-binding cassette, subfamily B, HAIF transporter
K19774 DVE1; homeobox domain-containing protein
K13113 UBL5, HUB1; ubiquitin-like protein 5
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K17794 TIM23; mitochondrial import inner membrane translocase subunit TIM23
K04043 dnaK, HSPA9; molecular chaperone DnaK
K04077 groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
|
04213 Longevity regulating pathway - multiple species [PATH:ko04213]
|
|
09159 Environmental adaptation
|
|
09160 Human Diseases
|
|
09161 Cancer: overview
|
05200 Pathways in cancer [PATH:ko05200]
|
05202 Transcriptional misregulation in cancer [PATH:ko05202]
|
05206 MicroRNAs in cancer [PATH:ko05206]
|
05205 Proteoglycans in cancer [PATH:ko05205]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
|
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K04439 ARRB; beta-arrestin
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K02213 CDC6; cell division control protein 6
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K04503 CCND1; G1/S-specific cyclin-D1
K04806 CHRNA4; nicotinic acetylcholine receptor alpha-4
K04813 CHRNB2; nicotinic acetylcholine receptor beta-2
K04805 CHRNA3; nicotinic acetylcholine receptor alpha-3
K04815 CHRNB4; nicotinic acetylcholine receptor beta-4
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04377 MYC; Myc proto-oncogene protein
K02161 BCL2; apoptosis regulator Bcl-2
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05448 VEGFA; vascular endothelial growth factor A
K18497 FGF2; fibroblast growth factor 2
K04141 ADRB1; adrenergic receptor beta-1
K04142 ADRB2; adrenergic receptor beta-2
K04143 ADRB3; adrenergic receptor beta-3
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K02158 BAD; Bcl-2-antagonist of cell death
K04810 CHRNA9; nicotinic acetylcholine receptor alpha-9
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K08539 VDR, NR1I1; vitamin D3 receptor
K10152 CCND3; G1/S-specific cyclin-D3
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K25039 PAQR7, MPRA; membrane progestin receptor alpha
K25040 PAQR8, MPRB; membrane progestin receptor beta
K25041 PAQR5, MPRG; membrane progestin receptor gamma
K08556 PGR, NR3C3; progesterone receptor
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K15618 BCL6; B-cell lymphoma 6 protein
K09206 KLF5; krueppel-like factor 5
K17846 KLF4; krueppel-like factor 4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K20994 NOTCH2; Notch 2
K06052 JAG1, CD339; jagged-1
K17018 MIR141; microRNA 141
K16995 MIR29A; microRNA 29a
K16996 MIR29B; microRNA 29b
K16997 MIR29C; microRNA 29c
K08557 AR, NR3C4; androgen receptor
K16980 MIRLET7; microRNA let-7
K04357 EGF; epidermal growth factor
K04358 FGF; fibroblast growth factor
K06051 DLL; delta
K15730 PTGES3; cytosolic prostaglandin-E synthase [EC:5.3.99.3]
K17767 AIP, XAP2; AH receptor-interacting protein
K09093 AHR; aryl hydrocarbon receptor
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K23940 KPNA1; importin subunit alpha-5
K15043 KPNA2_7; importin subunit alpha-1/8
K23583 KPNA3_4; importin subunit alpha-4/3
K15042 KPNA5_6; importin subunit alpha-6/7
K14293 KPNB1, IPO1; importin subunit beta-1
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K07408 CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K01253 EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
K22368 EPHX3; epoxide hydrolase 3 [EC:3.3.2.10]
K22369 EPHX4; epoxide hydrolase 4 [EC:3.3.-.-]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K17709 CYP2B6; cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K08541 NR1I3, CAR; constitutive androstane receptor
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K17689 CYP3A4; cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
|
05203 Viral carcinogenesis [PATH:ko05203]
|
K21854 X; Orthohepadnavirus protein X
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K10610 DDB1; DNA damage-binding protein 1
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08665 HPN; hepsin [EC:3.4.21.106]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04735 RELA; transcription factor p65
K09254 REL; c-Rel proto-oncogene protein
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04451 TP53, P53; tumor protein p53
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K15041 VDAC3; voltage-dependent anion channel protein 3
K22271 Core; Hepatitis C virus core protein
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K15413 SP100; nuclear body protein Sp100
K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K11594 DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K22273 NS3; Hepatitis C virus serine protease / helicase NS3 [EC:3.4.21.98 3.6.1.15 3.6.4.13]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K11252 H2B; histone H2B
K11254 H4; histone H4
K22275 NS5A; Hepatitis C virus non-structural protein 5A
K02159 BAX; apoptosis regulator BAX
K04364 GRB2; growth factor receptor-bound protein 2
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
K19461 EBNA1, BKRF1; Lymphocryptovirus nuclear antigen 1
K19456 EBNALP; Lymphocryptovirus nuclear antigen leader protein
K19457 EBNA2; Lymphocryptovirus nuclear antigen 2
K21855 EBNA3, EBNA3A; Lymphocryptovirus nuclear antigen 3
K21856 EBNA4, EBNA3B; Lymphocryptovirus nuclear antigen 4
K19458 EBNA6, EBNA3C; Lymphocryptovirus nuclear antigen 6
K19459 LMP1; Lymphocryptovirus latent membrane protein 1
K19460 LMP2A; Lymphocryptovirus latent membrane protein 2A
K11838 USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K06053 RBPSUH, RBPJK; recombining binding protein suppressor of hairless
K06063 SNW1, SKIIP, SKIP; SNW domain-containing protein 1
K03141 TFIIH1, GTF2H1, TFB1; transcription initiation factor TFIIH subunit 1
K03142 TFIIH2, GTF2H2, SSL1; transcription initiation factor TFIIH subunit 2
K03143 TFIIH3, GTF2H3, TFB4; transcription initiation factor TFIIH subunit 3
K03144 TFIIH4, GTF2H4, TFB2; transcription initiation factor TFIIH subunit 4
K03136 TFIIE1, GTF2E1, TFA1, tfe; transcription initiation factor TFIIE subunit alpha
K03137 TFIIE2, GTF2E2, TFA2; transcription initiation factor TFIIE subunit beta
K15979 SND1; staphylococcal nuclease domain-containing protein 1
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K03124 TFIIB, GTF2B, SUA7, tfb; transcription initiation factor TFIIB
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06627 CCNA; cyclin-A
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K16174 MRPS18B, MRPS18-2; small subunit ribosomal protein S18b, mitochondrial
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09849 TRAF5; TNF receptor-associated factor 5
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K21812 E5; Alphapapillomavirus protein E5
K21807 E6; Alphapapillomavirus protein E6
K21809 E7; Alphapapillomavirus protein E7
K02146 ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
K10587 UBE3A, E6AP; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
K12076 DLG1; disks large protein 1
K16175 SCRIB; protein scribble
K05760 PXN; paxillin
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K05411 IRF3; interferon regulatory factor 3
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K10691 UBR4, ZUBR1; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
K04448 JUN; transcription factor AP-1
K11643 CHD4, MI2B; chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
K11408 HDAC7; histone deacetylase 7 [EC:3.5.1.98]
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
K11409 HDAC9; histone deacetylase 9 [EC:3.5.1.98]
K18671 HDAC10; histone deacetylase 10 [EC:3.5.1.98]
K11418 HDAC11; histone deacetylase 11 [EC:3.5.1.98]
K00873 PK, pyk; pyruvate kinase [EC:2.7.1.40]
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K09504 DNAJA3; DnaJ homolog subfamily A member 3
K21857 tax; Deltaretrovirus protein Tax-1
K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
K03122 TFIIA1, GTF2A1, TOA1; transcription initiation factor TFIIA large subunit
K03123 TFIIA2, GTF2A2, TOA2; transcription initiation factor TFIIA small subunit
K04378 SRF; serum response factor
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K08053 RASA2, GAP1M; Ras GTPase-activating protein 2
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04513 RHOA; Ras homolog gene family, member A
K05768 GSN; gelsolin
K05699 ACTN1_4; actinin alpha 1/4
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K15305 VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
K15306 RANBP1; Ran-binding protein 1
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K21653 vIRF1, K9; KSHV interferon regulatory factor-like protein 1
K21654 vIRF2, K11; KSHV interferon regulatory factor-like protein 2
K21652 vIRF3; KSHV interferon regulatory factor-like protein 3
K21858 vIRF4, K10; KSHV interferon regulatory factor-like protein 4
K21859 KIE2, ORF45; KSHV transcription activator ORF45
K21650 KIE1, ORF50; KSHV transcription activator ORF50
K21670 vIL6, K2; KSHV interleukin 6
K21659 K6; KSHV protein K6
K21657 K4; KSHV macrophage inflammatory protein 2
K21658 K4.1; KSHV protein vCCL3
K21656 K12; KSHV protein K12
K21662 vFLIP, K13, ORF71; KSHV FLICE inhibitory protein
K21661 vIAP, K7; KSHV inhibitor of apoptosis protein
K21664 vLANA, ORF73; KSHV latency-associated nuclear antigen
K21663 vCyclin, ORF72; KSHV cyclin homolog
K21660 vBCL2, ORF16; KSHV apoptosis regulator BCL2 homolog
K21649 ORF4; KSHV complement control protein
K21665 MIR1, K3; KSHV E3 ubiquitin-protein ligase MIR1 [EC:2.3.2.36]
K21666 MIR2, K5; KSHV E3 ubiquitin-protein ligase MIR2 [EC:2.3.2.36]
K21667 vGPCR; KSHV G-protein coupled receptor
K21669 K1; KSHV protein K1
K21651 K15; KSHV signal transducing membrane protein
K21860 K14; KSHV OX-2 membrane glycoprotein
K21861 ORF35; KSHV protein ORF35
K09447 IRF7; interferon regulatory factor 7
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04179 CCR4, CD194; C-C chemokine receptor type 4
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02158 BAD; Bcl-2-antagonist of cell death
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K03990 C3; complement component 3
K06751 MHC1; MHC class I antigen
|
05230 Central carbon metabolism in cancer [PATH:ko05230]
|
05231 Choline metabolism in cancer [PATH:ko05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:ko05210]
|
05212 Pancreatic cancer [PATH:ko05212]
|
05225 Hepatocellular carcinoma [PATH:ko05225]
|
05226 Gastric cancer [PATH:ko05226]
|
05214 Glioma [PATH:ko05214]
|
05216 Thyroid cancer [PATH:ko05216]
|
05221 Acute myeloid leukemia [PATH:ko05221]
|
05220 Chronic myeloid leukemia [PATH:ko05220]
|
05217 Basal cell carcinoma [PATH:ko05217]
|
05218 Melanoma [PATH:ko05218]
|
05211 Renal cell carcinoma [PATH:ko05211]
|
05219 Bladder cancer [PATH:ko05219]
|
05215 Prostate cancer [PATH:ko05215]
|
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09435 ERG; transcriptional regulator ERG
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K09299 ZEB1; zinc finger homeobox protein 1
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K15619 SPINT1; Kunitz-type protease inhibitor 1
K15593 ETV5; ets translocation variant 5
K04526 INS; insulin
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K05459 IGF1; insulin-like growth factor 1
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K02105 CTNNB1; catenin beta 1
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02161 BCL2; apoptosis regulator Bcl-2
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K08557 AR, NR3C4; androgen receptor
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K01351 KLK3, PSA; semenogelase [EC:3.4.21.77]
|
05213 Endometrial cancer [PATH:ko05213]
|
05224 Breast cancer [PATH:ko05224]
|
05222 Small cell lung cancer [PATH:ko05222]
|
05223 Non-small cell lung cancer [PATH:ko05223]
|
|
09172 Infectious disease: viral
|
05166 Human T-cell leukemia virus 1 infection [PATH:ko05166]
|
K24862 gp46; HTLV envelope surface glycoprotein gp46
K24863 gp21; HTLV envelope transmembrane protein gp21
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06724 NRP1, CD304; neuropilin 1
K04377 MYC; Myc proto-oncogene protein
K08874 TRRAP; transformation/transcription domain-associated protein
K11304 TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
K10151 CCND2; G1/S-specific cyclin-D2
K23068 p30II; HTLV-1 accessory protein p30II
K05718 ITGAL, CD11a; integrin alpha L
K06464 ITGB2, CD18; integrin beta 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06454 CD4; T-cell surface glycoprotein CD4
K19259 env; Deltaretrovirus envelope glycoprotein gp62
K25051 MA; HTLV-1 matrix protein
K06271 TLN; talin
K23069 p12I; HTLV-1 accessory protein p12I
K23018 rex; HTLV-1 rex polyprotein
K15304 RANBP3; Ran-binding protein 3
K07936 RAN; GTP-binding nuclear protein Ran
K14290 XPO1, CRM1; exportin-1
K08057 CALR; calreticulin
K08054 CANX; calnexin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05429 IL2; interleukin 2
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K23070 p13; HTLV-1 accessory protein p13
K05862 VDAC1; voltage-dependent anion channel protein 1
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05770 TSPO, BZRP; translocator protein
K15305 VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
K15306 RANBP1; Ran-binding protein 1
K21857 tax; Deltaretrovirus protein Tax-1
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K06637 BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K03348 APC1, ANAPC1; anaphase-promoting complex subunit 1
K03349 APC2, ANAPC2; anaphase-promoting complex subunit 2
K03350 APC3, CDC27; anaphase-promoting complex subunit 3
K03351 APC4, ANAPC4; anaphase-promoting complex subunit 4
K03352 APC5, ANAPC5; anaphase-promoting complex subunit 5
K03353 APC6, CDC16; anaphase-promoting complex subunit 6
K03354 APC7, ANAPC7; anaphase-promoting complex subunit 7
K03355 APC8, CDC23; anaphase-promoting complex subunit 8
K03357 APC10, ANAPC10, DOC1; anaphase-promoting complex subunit 10
K03358 APC11, ANAPC11; anaphase-promoting complex subunit 11
K03359 APC12, CDC26; anaphase-promoting complex subunit 12
K12456 APC13, ANAPC13; anaphase-promoting complex subunit 13
K25228 APC15, ANAPC15; anaphase-promoting complex subunit 15
K25229 APC16, ANAPC16; anaphase-promoting complex subunit 16
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10152 CCND3; G1/S-specific cyclin-D3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06627 CCNA; cyclin-A
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K12076 DLG1; disks large protein 1
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K01397 MMP7; matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
K23071 HBZ; HTLV-1 basic zipper factor
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K15307 GPS2; G protein pathway suppressor 2
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05151 TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K15308 TTP; tristetraprolin
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05433 IL15; interleukin 15
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05405 IL6; interleukin 6
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08065 NFYB, HAP3; nuclear transcription Y subunit beta
K06752 MHC2; MHC class II antigen
K04378 SRF; serum response factor
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K04375 ELK1; ETS domain-containing protein Elk-1
K09438 SPI1; transcription factor PU.1
K02678 ETS1, pnt; C-ets-1
K21932 ETS2; C-ets-2
K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
K04379 FOS; proto-oncogene protein c-fos
K09203 EGR1; early growth response protein 1
K04502 FOSL1; fos-like antigen 1
K12496 EGR2; early growth response protein 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K15309 CRTC1, TORC1; CREB-regulated transcription coactivator 1
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16334 CRTC3, TORC3; CREB-regulated transcription coactivator 3
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
K09063 TCF3, E2A; transcription factor E2-alpha
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K02159 BAX; apoptosis regulator BAX
K06622 CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K09341 MSX; homeobox protein MSX
K25052 CA; HTLV-1 capsid protein
K25053 NC; HTLV-1 nucleocapsid protein
K25054 PR; HTLV-1 protease [EC:3.4.23.-]
K25055 RT; HTLV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.4]
K25056 IN; HTLV-1 integrase
|
05170 Human immunodeficiency virus 1 infection [PATH:ko05170]
|
05161 Hepatitis B [PATH:ko05161]
|
K23128 S; Orthohepadnavirus large envelope protein
K06255 HSPG2; basement membrane-specific heparan sulfate proteoglycan core protein
K14341 SLC10A1, NTCP; solute carrier family 10 (sodium/bile acid cotransporter), member 1
K21854 X; Orthohepadnavirus protein X
K23129 C; Orthohepadnavirus capsid protein
K21037 P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H [EC:2.7.7.7 2.7.7.49 3.1.26.4]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K23605 SMAD3; mothers against decapentaplegic homolog 3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K10610 DDB1; DNA damage-binding protein 1
K10140 DDB2; DNA damage-binding protein 2
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K02161 BCL2; apoptosis regulator Bcl-2
K02158 BAD; Bcl-2-antagonist of cell death
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K02084 APAF1; apoptotic protease-activating factor
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04451 TP53, P53; tumor protein p53
K06627 CCNA; cyclin-A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K03662 ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K15041 VDAC3; voltage-dependent anion channel protein 3
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04448 JUN; transcription factor AP-1
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K10030 IL8, CXCL8; interleukin 8
K04802 PCNA; proliferating cell nuclear antigen
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04375 ELK1; ETS domain-containing protein Elk-1
K10159 TLR2, CD282; toll-like receptor 2
K04729 MYD88; myeloid differentiation primary response protein MyD88
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K10160 TLR4, CD284; toll-like receptor 4
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K05405 IL6; interleukin 6
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K05401 TLR3, CD283; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K12646 DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K11594 DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
|
05160 Hepatitis C [PATH:ko05160]
|
05171 Coronavirus disease - COVID-19 [PATH:ko05171]
|
05164 Influenza A [PATH:ko05164]
|
05162 Measles [PATH:ko05162]
|
05168 Herpes simplex virus 1 infection [PATH:ko05168]
|
05163 Human cytomegalovirus infection [PATH:ko05163]
|
K22773 gB, UL55; Betaherpesvirinae envelope glycoprotein B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K22774 UL123; HCMV immediate-early protein 1
K22775 UL122; Cytomegalovirus viral transcription factor IE2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K22776 UL38; Cytomegalovirus apoptosis inhibitor UL38
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04684 SP1; transcription factor Sp1
K22777 gH, UL75; Cytomegalovirus envelope glycoprotein H
K22778 gL, UL115; Cytomegalovirus envelope glycoprotein L
K06487 ITGAV, CD51; integrin alpha V
K06493 ITGB3, CD61; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K22779 UL82; Cytomegalovirus tegument protein pp71
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K09849 TRAF5; TNF receptor-associated factor 5
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K22780 UL26; Cytomegalovirus tegument protein UL26
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K10030 IL8, CXCL8; interleukin 8
K05405 IL6; interleukin 6
K22781 US28; HCMV envelope protein US28
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K16529 ARHGEF13; A-kinase anchor protein 13
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K02105 CTNNB1; catenin beta 1
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
K05055 IL6R, CD126; interleukin 6 receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05448 VEGFA; vascular endothelial growth factor A
K22782 UL33; Cytomegalovirus G-protein coupled receptor UL33
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K22783 US27; HCMV envelope glycoprotein US27
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K05760 PXN; paxillin
K21533 vIL10; Herpesviridae/Poxviridae viral interleukin 10
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K21046 UL146; HCMV chemokine vCXCL1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K22784 UL22A; HCMV glycoprotein UL22A
K04176 CCR1, CD191; C-C chemokine receptor type 1
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04180 CCR5, CD195; C-C chemokine receptor type 5
K22785 US6; HCMV membrane glycoprotein US6
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K21050 US2; HCMV unique short US2 glycoprotein
K22786 US11; HCMV membrane glycoprotein US11
K22787 US3; HCMV membrane glycoprotein US3
K21051 US10; HCMV unique short US10 glycoprotein
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K22788 UL36; Cytomegalovirus viral inhibitor of caspase-8-induced apoptosis
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K22789 UL37; UL37 HCMV immediate early glycoprotein
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
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05167 Kaposi sarcoma-associated herpesvirus infection [PATH:ko05167]
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05169 Epstein-Barr virus infection [PATH:ko05169]
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05165 Human papillomavirus infection [PATH:ko05165]
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09171 Infectious disease: bacterial
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09174 Infectious disease: parasitic
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09163 Immune disease
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09164 Neurodegenerative disease
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05010 Alzheimer disease [PATH:ko05010]
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K06704 ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
K06059 ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
K04520 APP; amyloid beta A4 protein
K04532 NAE1, APPBP1; NEDD8-activating enzyme E1 regulatory subunit
K04529 APBB1, FE65; amyloid beta A4 precursor protein-binding family B member 1
K00134 GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K04521 BACE1; beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46]
K07747 BACE2; beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45]
K20723 RTN3; reticulon-3
K20720 RTN4; reticulon-4
K06170 PSENEN, PEN2; presenilin enhancer 2
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2, PS2; presenilin 2 [EC:3.4.23.-]
K06171 NCSTN; nicastrin
K06172 APH1; gamma-secretase subunit APH-1
K01408 IDE, ide; insulysin [EC:3.4.24.56]
K01389 MME, CD10; neprilysin [EC:3.4.24.11]
K04380 MAPT, TAU; microtubule-associated protein tau
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K08683 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
K05864 PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K01059 LPL; lipoprotein lipase [EC:3.1.1.34]
K04524 APOE; apolipoprotein E
K04550 LRP1, CD91; low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K02158 BAD; Bcl-2-antagonist of cell death
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04133 CHRM5; muscarinic acetylcholine receptor M5
K04604 GRM5; metabotropic glutamate receptor 5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K20858 MCU; calcium uniporter protein, mitochondrial
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04963 RYR3; ryanodine receptor 3
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K09027 XBP1; X box-binding protein 1
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K11716 CDK5R1; cyclin-dependent kinase 5 activator 1
K14709 SLC39A1_2_3, ZIP1_2_3; solute carrier family 39 (zinc transporter), member 1/2/3
K14710 SLC39A4, ZIP4; solute carrier family 39 (zinc transporter), member 4
K14711 SLC39A5, ZIP5; solute carrier family 39 (zinc transporter), member 5
K14712 SLC39A6, LIV1, ZIP6; solute carrier family 39 (zinc transporter), member 6
K14713 SLC39A7, KE4, ZIP7; solute carrier family 39 (zinc transporter), member 7
K14714 SLC39A8, ZIP8; solute carrier family 39 (zinc transporter), member 8
K14715 SLC39A9, ZIP9; solute carrier family 39 (zinc transporter), member 9
K14716 SLC39A10, ZIP10; solute carrier family 39 (zinc transporter), member 10
K14717 SLC39A11, ZIP11; solute carrier family 39 (zinc transporter), member 11
K14718 SLC39A12, ZIP12; solute carrier family 39 (zinc transporter), member 12
K14719 SLC39A13, ZIP13; solute carrier family 39 (zinc transporter), member 13
K14720 SLC39A14, ZIP14; solute carrier family 39 (zinc transporter), member 14
K21398 SLC11A2, DMT1, NRAMP2; natural resistance-associated macrophage protein 2
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02165 DKK1_2_4; dickkopf 1/2/4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K04690 FZDN, fz3; frizzled
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K08008 NOX1, MOX1; NADPH oxidase 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K21423 NOX4, RENOX; NADPH oxidase 4 [EC:1.6.3.-]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K04528 SNCA; alpha-synuclein
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04526 INS; insulin
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K19730 ATG101; autophagy-related protein 101
K08331 ATG13; autophagy-related protein 13
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K08334 BECN, VPS30, ATG6; beclin
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K21246 NRBF2; nuclear receptor-binding factor 2
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K17906 ATG2; autophagy-related protein 2
K17908 WIPI1_2, ATG18; autophagy-related protein 18
|
05012 Parkinson disease [PATH:ko05012]
|
K04266 ADORA2A, ADOR; adenosine receptor A2a
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04145 DRD2; dopamine receptor D2
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04144 DRD1; dopamine receptor D1
K03178 UBE1, UBA1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
K10698 UBE1L, UBA7; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K04552 UBE2L3, UBCH7; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
K04553 UBE2L6, UBCH8; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
K04554 UBE2J2, NCUBE2, UBC6; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
K10578 UBE2J1, NCUBE1, UBC6; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
K04555 UBE2G2, UBC7; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
K10575 UBE2G1, UBC7; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
K04556 PARK2; parkin [EC:2.3.2.31]
K04528 SNCA; alpha-synuclein
K04243 GPR37; prosaposin receptor
K04557 SEPT5, PNUTL1, CDCREL1; septin 5
K04558 SNCAIP; synphilin-1
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04380 MAPT, TAU; microtubule-associated protein tau
K04963 RYR3; ryanodine receptor 3
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K09027 XBP1; X box-binding protein 1
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K00274 MAO, aofH; monoamine oxidase [EC:1.4.3.4]
K05036 SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K08155 SLC18A1_2, VMAT; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K21398 SLC11A2, DMT1, NRAMP2; natural resistance-associated macrophage protein 2
K14709 SLC39A1_2_3, ZIP1_2_3; solute carrier family 39 (zinc transporter), member 1/2/3
K14710 SLC39A4, ZIP4; solute carrier family 39 (zinc transporter), member 4
K14711 SLC39A5, ZIP5; solute carrier family 39 (zinc transporter), member 5
K14712 SLC39A6, LIV1, ZIP6; solute carrier family 39 (zinc transporter), member 6
K14713 SLC39A7, KE4, ZIP7; solute carrier family 39 (zinc transporter), member 7
K14714 SLC39A8, ZIP8; solute carrier family 39 (zinc transporter), member 8
K14715 SLC39A9, ZIP9; solute carrier family 39 (zinc transporter), member 9
K14716 SLC39A10, ZIP10; solute carrier family 39 (zinc transporter), member 10
K14717 SLC39A11, ZIP11; solute carrier family 39 (zinc transporter), member 11
K14718 SLC39A12, ZIP12; solute carrier family 39 (zinc transporter), member 12
K14719 SLC39A13, ZIP13; solute carrier family 39 (zinc transporter), member 13
K14720 SLC39A14, ZIP14; solute carrier family 39 (zinc transporter), member 14
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
K20858 MCU; calcium uniporter protein, mitochondrial
K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
K08669 HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
K09488 TRAP1, HSP75; TNF receptor-associated protein 1
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K05687 PARK7; protein DJ-1 [EC:3.5.1.124]
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02159 BAX; apoptosis regulator BAX
K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
K06030 MFN2, FZO1; mitofusin 2 [EC:3.6.5.-]
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K04451 TP53, P53; tumor protein p53
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K03671 TXN, trxA; thioredoxin
K02308 DAXX; death-associated protein 6
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
|
05014 Amyotrophic lateral sclerosis [PATH:ko05014]
|
K04451 TP53, P53; tumor protein p53
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K04726 BID; BH3 interacting domain death agonist
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02159 BAX; apoptosis regulator BAX
K02158 BAD; Bcl-2-antagonist of cell death
K02084 APAF1; apoptotic protease-activating factor
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K05862 VDAC1; voltage-dependent anion channel protein 1
K11518 TOM40; mitochondrial import receptor subunit TOM40
K20858 MCU; calcium uniporter protein, mitochondrial
K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
K04556 PARK2; parkin [EC:2.3.2.31]
K19946 OPTN, FIP2; optineurin
K14381 SQSTM1; sequestosome 1
K10435 MAP1LC; microtubule-associated protein 1 light chain
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K23610 WDR41; WD repeat-containing protein 41
K23611 SMCR8; guanine nucleotide exchange protein SMCR8
K23609 C9ORF72; guanine nucleotide exchange protein C9orf72
K07901 RAB8A, MEL; Ras-related protein Rab-8A
K07925 RAB39B; Ras-related protein Rab-39B
K07874 RAB1A; Ras-related protein Rab-1A
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K19730 ATG101; autophagy-related protein 101
K08331 ATG13; autophagy-related protein 13
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K08334 BECN, VPS30, ATG6; beclin
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K21246 NRBF2; nuclear receptor-binding factor 2
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K17906 ATG2; autophagy-related protein 2
K17908 WIPI1_2, ATG18; autophagy-related protein 18
K04575 ALS2; amyotrophic lateral sclerosis 2 protein
K07887 RAB5A; Ras-related protein Rab-5A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K12192 CHMP2B; charged multivesicular body protein 2B
K22913 FIG4; phosphatidylinositol 3,5-bisphosphate 5-phosphatase [EC:3.1.3.-]
K19026 SPG11; spatacsin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04523 UBQLN, DSK2; ubiquilin
K13525 VCP, CDC48; transitional endoplasmic reticulum ATPase
K11519 DERL1; Derlin-1
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
K23600 TARDBP, TDP43; TAR DNA-binding protein 43
K13098 TLS, FUS; RNA-binding protein FUS
K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
K23625 ATXN2_2L; ataxin 2/2L
K13213 MATR3; matrin 3
K16631 ANG, RNASE5; angiogenin [EC:3.1.27.-]
K12882 NCBP1, CBP80; nuclear cap-binding protein subunit 1
K12881 THOC4, ALY; THO complex subunit 4
K12892 SRSF3, SFRS3; serine/arginine-rich splicing factor 3
K12896 SRSF7, SFRS7; serine/arginine-rich splicing factor 7
K14284 NXF, TAP, MEX67; nuclear RNA export factor
K14285 NXT1_2, P15; NTF2-related export protein 1/2
K18723 GLE1; nucleoporin GLE1
K09291 TPR, MLP1, MLP2; nucleoprotein TPR
K14295 NUP50, NPAP60; nuclear pore complex protein Nup50
K14296 NUP153; nuclear pore complex protein Nup153
K14297 NUP98, ADAR2, NUP116; nuclear pore complex protein Nup98-Nup96
K14298 RAE1, GLE2; mRNA export factor
K14004 SEC13; protein transport protein SEC13
K14299 SEH1; nucleoporin SEH1
K14300 NUP133; nuclear pore complex protein Nup133
K14301 NUP107, NUP84; nuclear pore complex protein Nup107
K14302 NUP37; nuclear pore complex protein Nup37
K14303 NUP160, NUP120; nuclear pore complex protein Nup160
K14304 NUP85; nuclear pore complex protein Nup85
K14305 NUP43; nuclear pore complex protein Nup43
K14306 NUP62, NSP1; nuclear pore complex protein Nup62
K14307 NUPL1, NUP49; nucleoporin p58/p45
K14308 NUP54, NUP57; nuclear pore complex protein Nup54
K14309 NUP93, NIC96; nuclear pore complex protein Nup93
K14310 NUP205, NUP192; nuclear pore complex protein Nup205
K14311 NUP188; nuclear pore complex protein Nup188
K14312 NUP155, NUP170, NUP157; nuclear pore complex protein Nup155
K14313 NUP35, NUP53; nuclear pore complex protein Nup53
K14314 NUP210, GP210; nuclear pore complex protein Nup210
K14315 NDC1, TMEM48; nucleoporin NDC1
K14316 POM121, NUP121; nuclear pore complex protein Nup121
K14317 NUP214, CAN; nuclear pore complex protein Nup214
K14318 NUP88; nuclear pore complex protein Nup88
K12172 RANBP2, NUP358; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
K10706 SETX, ALS4; senataxin [EC:5.6.2.-]
K22759 CHCHD10; coiled-coil-helix-coiled-coil-helix domain-containing protein 10
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K10707 VAPB, ALS8; vesicle-associated membrane protein-associated protein B
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K09027 XBP1; X box-binding protein 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K20719 SIGMAR1; sigma non-opioid intracellular receptor
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K02308 DAXX; death-associated protein 6
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K04569 CCS; copper chaperone for superoxide dismutase
K00432 gpx, btuE, bsaA; glutathione peroxidase [EC:1.11.1.9]
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K07607 PRPH; peripherin
K04572 NEFL, NF-L; neurofilament light polypeptide
K04573 NEF3, NF-M; neurofilament medium polypeptide (neurofilament 3)
K04574 NEFH, NF-H; neurofilament heavy polypeptide
K05759 PFN; profilin
K05692 ACTB_G1; actin beta/gamma 1
K17095 ANXA7_11; annexin A7/11
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K04648 DCTN1; dynactin 1
K10424 DCTN2; dynactin 2
K10425 DCTN3; dynactin 3
K10426 DCTN4; dynactin 4
K10427 DCTN5; dynactin 5
K10428 DCTN6; dynactin 6
K16575 ACTR1, ARP1; centractin
K16576 ACTR10, ARP11; actin-related protein 10
K04647 HAP1; huntingtin-associated protein 1
K10408 DNAH; dynein axonemal heavy chain
K10410 DNALI; dynein axonemal light intermediate chain 1
K10409 DNAI1; dynein axonemal intermediate chain 1
K11143 DNAI2; dynein axonemal intermediate chain 2
K10411 DNAL1; dynein axonemal light chain 1
K10412 DNAL4; dynein axonemal light chain 4
K05613 SLC1A2, EAAT2; solute carrier family 1 (glial high affinity glutamate transporter), member 2
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
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05016 Huntington disease [PATH:ko05016]
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05017 Spinocerebellar ataxia [PATH:ko05017]
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05020 Prion disease [PATH:ko05020]
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K05634 PRNP, PrP, CD230; prion protein
K06491 NCAM, CD56; neural cell adhesion molecule
K05635 LAMC1; laminin, gamma 1
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K09553 STIP1; stress-induced-phosphoprotein 1
K04345 PKA; protein kinase A [EC:2.7.11.11]
K02159 BAX; apoptosis regulator BAX
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05214 GRIN3B; glutamate receptor ionotropic, NMDA 3B
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K02158 BAD; Bcl-2-antagonist of cell death
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K02084 APAF1; apoptotic protease-activating factor
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K20858 MCU; calcium uniporter protein, mitochondrial
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K03994 C5; complement component 5
K03995 C6; complement component 6
K03996 C7; complement component 7
K03997 C8A; complement component 8 subunit alpha
K03998 C8B; complement component 8 subunit beta
K03999 C8G; complement component 8 subunit gamma
K04000 C9; complement component 9
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K02599 NOTCH1; Notch 1
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K09203 EGR1; early growth response protein 1
K12499 CCL5; C-C motif chemokine 5
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
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05022 Pathways of neurodegeneration - multiple diseases [PATH:ko05022]
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K04520 APP; amyloid beta A4 protein
K04380 MAPT, TAU; microtubule-associated protein tau
K04528 SNCA; alpha-synuclein
K23600 TARDBP, TDP43; TAR DNA-binding protein 43
K13098 TLS, FUS; RNA-binding protein FUS
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K23625 ATXN2_2L; ataxin 2/2L
K04533 HD; huntingtin
K23616 ATXN1_1L; ataxin 1/1L
K11863 ATXN3, MJD; Ataxin-3 [EC:3.4.22.-]
K05634 PRNP, PrP, CD230; prion protein
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04133 CHRM5; muscarinic acetylcholine receptor M5
K23932 SPTBN2; spectrin beta, non-erythrocytic 2
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04556 PARK2; parkin [EC:2.3.2.31]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04966 TRPC3; transient receptor potential cation channel subfamily C member 3
K20719 SIGMAR1; sigma non-opioid intracellular receptor
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K15840 PDYN, PENKB; proenkephalin B (prodynorphin)
K11828 DLG4, PSD95; discs large protein 4
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K04849 CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04560 STX1A; syntaxin 1A
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2, PS2; presenilin 2 [EC:3.4.23.-]
K11519 DERL1; Derlin-1
K13525 VCP, CDC48; transitional endoplasmic reticulum ATPase
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
K03178 UBE1, UBA1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
K10698 UBE1L, UBA7; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]
K04552 UBE2L3, UBCH7; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
K04553 UBE2L6, UBCH8; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
K04554 UBE2J2, NCUBE2, UBC6; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
K10578 UBE2J1, NCUBE1, UBC6; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
K04555 UBE2G2, UBC7; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
K10575 UBE2G1, UBC7; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
K04243 GPR37; prosaposin receptor
K04557 SEPT5, PNUTL1, CDCREL1; septin 5
K04558 SNCAIP; synphilin-1
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K10707 VAPB, ALS8; vesicle-associated membrane protein-associated protein B
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K09027 XBP1; X box-binding protein 1
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K04418 MAP3K10, MLK2; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K05036 SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:7.1.2.2]
K02136 ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
K02161 BCL2; apoptosis regulator Bcl-2
K05862 VDAC1; voltage-dependent anion channel protein 1
K11518 TOM40; mitochondrial import receptor subunit TOM40
K20858 MCU; calcium uniporter protein, mitochondrial
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K02158 BAD; Bcl-2-antagonist of cell death
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
K08669 HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
K09488 TRAP1, HSP75; TNF receptor-associated protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04559 HIP1; huntingtin interacting protein 1
K04638 IFT57, HIPPI, ESRRBL1; intraflagellar transport protein 57
K08683 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
K05864 PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05687 PARK7; protein DJ-1 [EC:3.5.1.124]
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
K06030 MFN2, FZO1; mitofusin 2 [EC:3.6.5.-]
K19946 OPTN, FIP2; optineurin
K14381 SQSTM1; sequestosome 1
K10435 MAP1LC; microtubule-associated protein 1 light chain
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K23610 WDR41; WD repeat-containing protein 41
K23611 SMCR8; guanine nucleotide exchange protein SMCR8
K23609 C9ORF72; guanine nucleotide exchange protein C9orf72
K07901 RAB8A, MEL; Ras-related protein Rab-8A
K07925 RAB39B; Ras-related protein Rab-39B
K07874 RAB1A; Ras-related protein Rab-1A
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K19730 ATG101; autophagy-related protein 101
K08331 ATG13; autophagy-related protein 13
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
K08334 BECN, VPS30, ATG6; beclin
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K21246 NRBF2; nuclear receptor-binding factor 2
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K17906 ATG2; autophagy-related protein 2
K17908 WIPI1_2, ATG18; autophagy-related protein 18
K17603 ZFYVE1; zinc finger FYVE domain-containing protein 1
K04575 ALS2; amyotrophic lateral sclerosis 2 protein
K07887 RAB5A; Ras-related protein Rab-5A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K12192 CHMP2B; charged multivesicular body protein 2B
K22913 FIG4; phosphatidylinositol 3,5-bisphosphate 5-phosphatase [EC:3.1.3.-]
K19026 SPG11; spatacsin
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K02308 DAXX; death-associated protein 6
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K04569 CCS; copper chaperone for superoxide dismutase
K00432 gpx, btuE, bsaA; glutathione peroxidase [EC:1.11.1.9]
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K07607 PRPH; peripherin
K04572 NEFL, NF-L; neurofilament light polypeptide
K04573 NEF3, NF-M; neurofilament medium polypeptide (neurofilament 3)
K04574 NEFH, NF-H; neurofilament heavy polypeptide
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K04355 BDNF; brain-derived neurotrophic factor
K04648 DCTN1; dynactin 1
K10424 DCTN2; dynactin 2
K10425 DCTN3; dynactin 3
K10426 DCTN4; dynactin 4
K10427 DCTN5; dynactin 5
K10428 DCTN6; dynactin 6
K16575 ACTR1, ARP1; centractin
K16576 ACTR10, ARP11; actin-related protein 10
K04647 HAP1; huntingtin-associated protein 1
K10408 DNAH; dynein axonemal heavy chain
K10410 DNALI; dynein axonemal light intermediate chain 1
K10409 DNAI1; dynein axonemal intermediate chain 1
K11143 DNAI2; dynein axonemal intermediate chain 2
K10411 DNAL1; dynein axonemal light chain 1
K10412 DNAL4; dynein axonemal light chain 4
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K11716 CDK5R1; cyclin-dependent kinase 5 activator 1
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02165 DKK1_2_4; dickkopf 1/2/4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K04690 FZDN, fz3; frizzled
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08008 NOX1, MOX1; NADPH oxidase 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K21423 NOX4, RENOX; NADPH oxidase 4 [EC:1.6.3.-]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
|
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09165 Substance dependence
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05030 Cocaine addiction [PATH:ko05030]
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K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K01593 DDC, TDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
K08155 SLC18A1_2, VMAT; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K00274 MAO, aofH; monoamine oxidase [EC:1.4.3.4]
K05036 SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K04144 DRD1; dopamine receptor D1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04605 GRM2; metabotropic glutamate receptor 2
K04606 GRM3; metabotropic glutamate receptor 3
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04145 DRD2; dopamine receptor D2
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K15839 GPSM1, AGS3; G-protein signaling modulator 1
K13765 RGS9; regulator of G-protein signaling 9
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K15840 PDYN, PENKB; proenkephalin B (prodynorphin)
K04355 BDNF; brain-derived neurotrophic factor
K04448 JUN; transcription factor AP-1
K09029 FOSB; protein FosB
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K11716 CDK5R1; cyclin-dependent kinase 5 activator 1
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05214 GRIN3B; glutamate receptor ionotropic, NMDA 3B
K11828 DLG4, PSD95; discs large protein 4
K15494 PPP1R1B, DARPP32; protein phosphatase 1 regulatory subunit 1B
K05198 GRIA2; glutamate receptor 2
|
05031 Amphetamine addiction [PATH:ko05031]
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K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K01593 DDC, TDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
K08155 SLC18A1_2, VMAT; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K00274 MAO, aofH; monoamine oxidase [EC:1.4.3.4]
K05036 SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05214 GRIN3B; glutamate receptor ionotropic, NMDA 3B
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K04144 DRD1; dopamine receptor D1
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04560 STX1A; syntaxin 1A
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02183 CALM; calmodulin
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K15494 PPP1R1B, DARPP32; protein phosphatase 1 regulatory subunit 1B
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K15840 PDYN, PENKB; proenkephalin B (prodynorphin)
K15867 ARC; activity-regulated cytoskeleton-associated protein
K04379 FOS; proto-oncogene protein c-fos
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04448 JUN; transcription factor AP-1
K09029 FOSB; protein FosB
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
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05032 Morphine addiction [PATH:ko05032]
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05033 Nicotine addiction [PATH:ko05033]
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05034 Alcoholism [PATH:ko05034]
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K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K01593 DDC, TDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
K08155 SLC18A1_2, VMAT; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K00274 MAO, aofH; monoamine oxidase [EC:1.4.3.4]
K05036 SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05214 GRIN3B; glutamate receptor ionotropic, NMDA 3B
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
K11408 HDAC7; histone deacetylase 7 [EC:3.5.1.98]
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
K11409 HDAC9; histone deacetylase 9 [EC:3.5.1.98]
K18671 HDAC10; histone deacetylase 10 [EC:3.5.1.98]
K11418 HDAC11; histone deacetylase 11 [EC:3.5.1.98]
K11251 H2A; histone H2A
K11252 H2B; histone H2B
K11253 H3; histone H3
K11254 H4; histone H4
K11303 HAT1, KAT1; histone acetyltransferase 1 [EC:2.3.1.48]
K04144 DRD1; dopamine receptor D1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04145 DRD2; dopamine receptor D2
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K15014 SLC29A1_2_3, ENT1_2_3; solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3
K04266 ADORA2A, ADOR; adenosine receptor A2a
K04267 ADORA2B; adenosine receptor A2b
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K05256 CRH; corticotropin-releasing hormone
K05232 NPY; neuropeptide Y
K04355 BDNF; brain-derived neurotrophic factor
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K15840 PDYN, PENKB; proenkephalin B (prodynorphin)
K02183 CALM; calmodulin
K00908 CAMKK1; calcium/calmodulin-dependent protein kinase kinase 1 [EC:2.7.11.17]
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K09029 FOSB; protein FosB
K15494 PPP1R1B, DARPP32; protein phosphatase 1 regulatory subunit 1B
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K15985 PKIA; cAMP-dependent protein kinase inhibitor alpha
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09166 Cardiovascular disease
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05417 Lipid and atherosclerosis [PATH:ko05417]
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K14462 APOB; apolipoprotein B
K08760 APOA4; apolipoprotein A-IV
K08757 APOA1; apolipoprotein A-I
K12473 LDLR; low-density lipoprotein receptor
K08763 OLR1; oxidised low-density lipoprotein receptor 1
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K04513 RHOA; Ras homolog gene family, member A
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02159 BAX; apoptosis regulator BAX
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K09364 POU2F, OTF; POU domain transcription factor, class 2
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K07408 CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K17683 CYP2A6; cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
K17709 CYP2B6; cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
K17718 CYP2C8; cytochrome P450 family 2 subfamily C8 [EC:1.14.14.1]
K17719 CYP2C9; cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
K19722 AGER, RAGE; receptor for advanced glycosylation end products
K08008 NOX1, MOX1; NADPH oxidase 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K04393 CDC42; cell division control protein 42
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K14624 CCL2, MCP1; C-C motif chemokine 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K10030 IL8, CXCL8; interleukin 8
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K06494 SELE, CD62E; selectin, endothelial cell
K06496 SELP, CD62P; selectin, platelet
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04077 groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K26598 HSPA2; heat shock 70kDa protein 2
K09489 HSPA4; heat shock 70kDa protein 4
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K10159 TLR2, CD282; toll-like receptor 2
K05399 LBP; lipopolysaccharide-binding protein
K04391 CD14; monocyte differentiation antigen CD14
K05400 LY96, MD-2; lymphocyte antigen 96
K10160 TLR4, CD284; toll-like receptor 4
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09447 IRF7; interferon regulatory factor 7
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K06259 CD36; CD36 antigen
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K10169 TLR6, CD286; toll-like receptor 6
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K12499 CCL5; C-C motif chemokine 5
K05408 CCL3; C-C motif chemokine 3
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K05482 IL18, IL1F4; interleukin 18
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K10950 ERO1L; ERO1-like protein alpha [EC:1.8.4.-]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K09027 XBP1; X box-binding protein 1
K05641 ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
K05679 ABCG1; ATP-binding cassette, subfamily G (WHITE), member 1
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K20053 VLDLR; very low-density lipoprotein receptor
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K04396 CASP6; caspase 6 [EC:3.4.22.59]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K04451 TP53, P53; tumor protein p53
|
05418 Fluid shear stress and atherosclerosis [PATH:ko05418]
|
05410 Hypertrophic cardiomyopathy [PATH:ko05410]
|
05412 Arrhythmogenic right ventricular cardiomyopathy [PATH:ko05412]
|
05414 Dilated cardiomyopathy [PATH:ko05414]
|
05415 Diabetic cardiomyopathy [PATH:ko05415]
|
05416 Viral myocarditis [PATH:ko05416]
|
|
09167 Endocrine and metabolic disease
|
04930 Type II diabetes mellitus [PATH:ko04930]
|
04940 Type I diabetes mellitus [PATH:ko04940]
|
04950 Maturity onset diabetes of the young [PATH:ko04950]
|
04936 Alcoholic liver disease [PATH:ko04936]
|
04932 Non-alcoholic fatty liver disease [PATH:ko04932]
|
K05405 IL6; interleukin 6
K05055 IL6R, CD126; interleukin 6 receptor
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04526 INS; insulin
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K08536 NR1H3, LXRA; liver X receptor alpha
K08524 RXRA, NR2B1; retinoid X receptor alpha
K07197 SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
K09113 MLX; MAX-like protein X
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K05424 LEP; leptin
K05062 LEPR, CD295; leptin receptor
K07296 ADIPOQ, ACDC; adiponectin
K07297 ADIPOR; adiponectin receptor
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04419 MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K05632 ITCH, AIP4; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K09027 XBP1; X box-binding protein 1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K10030 IL8, CXCL8; interleukin 8
K13375 TGFB1; transforming growth factor beta-1
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K02159 BAX; apoptosis regulator BAX
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K08738 CYC; cytochrome c
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
|
04931 Insulin resistance [PATH:ko04931]
|
04933 AGE-RAGE signaling pathway in diabetic complications [PATH:ko04933]
|
04934 Cushing syndrome [PATH:ko04934]
|
K05256 CRH; corticotropin-releasing hormone
K04578 CRHR1; corticotropin releasing hormone receptor 1
K04579 CRHR2; corticotropin releasing hormone receptor 2
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K14970 MEN1, MNN1; menin
K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
K14961 RBBP5, SWD1, CPS50; COMPASS component SWD1
K14963 WDR5, SWD3, CPS30; COMPASS component SWD3
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
K09187 MLL2, ALR; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
K06622 CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K07843 RASD1; RAS, dexamethasone-induced Ras-related protein 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K09093 AHR; aryl hydrocarbon receptor
K17767 AIP, XAP2; AH receptor-interacting protein
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04850 CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K11839 USP8, UBP5; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
K05228 POMC; proopiomelanocortin
K04200 MC2R; melanocortin 2 receptor
K22398 MRAP; melanocortin-2 receptor accessory protein
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K08560 NR5A1, SF1; steroidogenic factor 1
K04684 SP1; transcription factor Sp1
K09355 PBX1; pre-B-cell leukemia transcription factor 1
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K16931 STAR; steroidogenic acute regulatory protein, mitochondrial
K14349 NCEH1, AADACL1; neutral cholesterol ester hydrolase 1 [EC:3.1.1.-]
K22499 ARMC5; armadillo repeat-containing protein 5
K09821 AGT, SERPINA8; angiotensinogen
K04166 AGTR1; angiotensin II receptor type 1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04913 KCNK2, K2P2.1; potassium channel subfamily K member 2
K04854 CACNA1G, CAV3.1; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H, CAV3.2; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I, CAV3.3; voltage-dependent calcium channel T type alpha-1I
K16056 ORAI1; calcium release-activated calcium channel protein 1
K04877 KCNA4, KV1.4; potassium voltage-gated channel Shaker-related subfamily A member 4
K04914 KCNK3, K2P3.1; potassium channel subfamily K member 3
K12473 LDLR; low-density lipoprotein receptor
K13885 SCARB1; scavenger receptor class B, member 1
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K01679 E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09181 Protein families: metabolism
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09182 Protein families: genetic information processing
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03000 Transcription factors [BR:ko03000]
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K09027 XBP1; X box-binding protein 1
K04448 JUN; transcription factor AP-1
K09028 JUNB; transcription factor jun-B
K04449 JUND; transcription factor jun-D
K04379 FOS; proto-oncogene protein c-fos
K09029 FOSB; protein FosB
K04502 FOSL1; fos-like antigen 1
K09030 FOSL2; fos-like antigen 2
K09031 FOSLN; fos-like antigen, invertebrate
K09032 ATF3, LRF1; activating transcription factor 3
K21406 ATF3, A3-3; activating transcription factor 3
K09033 JDP2; jun dimerization protein 2
K09034 BATF; ATF-like basic leucine zipper transcriptional factor
K09035 CMAF, MAF; transcription factor Maf
K07595 MAFA; transcription factor MAFA
K09036 MAFB; transcription factor MAFB
K09037 MAFF_G_K; transcription factor MAFF/G/K
K09038 NRL; neural retina-specific leucine zipper protein
K09039 NFE2; nuclear factor erythroid 2
K09040 NFE2L1_3; nuclear factor erythroid 2-related factor 1/3
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K09041 NFE2N, CNC; nuclear factor erythroid 2, invertebrate
K09042 BACH; transcription regulator BACH
K09464 GCN4; general control protein GCN4
K09043 YAP; AP-1-like transcription factor
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09044 ATF5; activating transcription factor 5
K09045 ATF7, ATFA; activating transcription factor 7
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K21548 CREBZF; ATF/CREB family transcription factor
K09051 SKO1, ATF1, PCR1; ATF/CREB family transcription factor
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K09052 CREM; cAMP response element modulator
K09053 ATF1; activating transcription factor 1
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K16230 HAC1; transcriptional activator HAC1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K10049 CEBPG; CCAAT/enhancer binding protein (C/EBP), gamma
K10050 CEBPD; CCAAT/enhancer binding protein (C/EBP), delta
K10051 CEBPE; CCAAT/enhancer binding protein (C/EBP), epsilon
K10052 CEBPN; CCAAT/enhancer binding protein (C/EBP), invertebrate
K23479 CCAAT/enhancer binding protein (C/EBP), other
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K09056 DBP; albumin D box-binding protein
K09057 HLF; hepatic leukemia factor
K09058 TEF; thyrotrophic embryonic factor
K09059 NFIL3, E4BP4; nuclear factor, interleukin 3 regulated
K14432 ABF; ABA responsive element binding factor
K14431 TGA; transcription factor TGA
K09060 GBF; plant G-box-binding factor
K16241 HY5; transcription factor HY5
K20557 VIP1; transcription factor VIP1
K25786 BZIP1S; bZIP transcription factor 1/2/11/44/53
K25784 BZIP9_10_25_63; bZIP transcription factor 9/10/25/63
K25783 BZIP17_28_49; bZIP transcription factor 17/28/49
K25785 BZIP19_23_24; bZIP transcription factor 19/23/24
K09061 GCF, C2orf3; GC-rich sequence DNA-binding factor
K12114 VRI; vrille
K09062 GT; protein giant
K27348 CES-2; transcription factor Ces-2
K06649 SWI4; regulatory protein SWI4
K06648 SWI6; regulatory protein SWI6
K21642 OPI1; transcriptional repressor OPI1
K21646 GCR1; glycolytic genes transcriptional activator GCR1
K21671 GCR2; glycolytic genes transcriptional activator GCR2
K21451 XLNR; xylanolytic transcriptional activator XlnR
K21452 MBZ1; bZIP-type transcription factor MBZ1
K09063 TCF3, E2A; transcription factor E2-alpha
K15603 TCF4_12; transcription factor 4/12
K09064 MYOD1, MYF3; myogenic factor 3
K18483 MYF4, MYOG; myogenic factor 4 (myogenin)
K18484 MYF5; myogenic factor 5
K18485 MYF6, MRF4; myogenic factor 6
K09066 FIGLA; factor in the germline alpha
K09067 ASCL; achaete-scute complex protein
K09068 TAL; T-cell acute lymphocytic leukemia protein
K15604 LYL1; protein lyl-1
K09069 TWIST; twist
K09070 TCF15, PARAXIS; transcription factor 15
K09071 HAND1; heart-and neural crest derivatives-expressed protein 1
K18486 HAND2; heart-and neural crest derivatives-expressed protein 2
K09072 MSC; musculin (activated B-cell factor-1)
K09073 PTF1A; pancreas-specific transcription factor 1a
K22400 FERD3L; Fer3-like protein
K09074 TYE7; fungal twist-like factor
K09075 NHLH, HEN, NSCL; nescient helix-loop-helix protein
K09076 MESP; mesoderm posterior
K09077 MSGN1; mesogenin 1
K08033 NEUROD1; neurogenic differentiation factor 1
K09078 NEUROD2; neurogenic differentiation factor 2
K09079 NEUROD4, ATOH3, MATH3; neurogenic differentiation factor 4
K09080 NEUROD6, ATOH2, MATH2; neurogenic differentiation factor 6
K09081 NEUROG1; neurogenin 1
K09082 NEUROG2; neurogenin 2
K08028 NEUROG3; neurogenin 3
K09083 ATOH1_7; atonal protein 1/7
K09084 ATOH8; atonal protein 8
K24145 BHLHA9; class A basic helix-loop-helix protein 9
K09085 BHLHB1_6_7; class B basic helix-loop-helix protein 1/6/7
K08040 BHLHB8, MIST1; class B basic helix-loop-helix protein 8
K09086 BHLHB4_5, BETA; class B basic helix-loop-helix protein 4/5
K06054 HES1; hairy and enhancer of split 1
K09087 HES2_6_7; hairy and enhancer of split 2/6/7
K09088 HES3; hairy and enhancer of split 3
K09089 HES4; hairy and enhancer of split 4
K06055 HES5; hairy and enhancer of split 5
K09090 HESN; hairy and enhancer of split, invertebrate
K09091 HEY; hairy and enhancer of split related with YRPW motif
K03729 BHLHB2, DEC1; class B basic helix-loop-helix protein 2
K03730 BHLHB3, DEC2; class B basic helix-loop-helix protein 3
K09092 TCFL5, CHA; transcription factor-like 5
K27237 CWO; transcription factor CWO
K06658 PHO4; phosphate system positive regulatory protein PHO4
K06654 PHO80; phosphate system cyclin PHO80
K09093 AHR; aryl hydrocarbon receptor
K09094 AHRR, AHH; aryl hydrocarbon receptor repressor
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
K09096 HIF3A; hypoxia-inducible factor 3 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K09098 NPAS1_3; neuronal PAS domain-containing protein 1/3
K09026 NPAS2; neuronal PAS domain-containing protein 2
K26457 NPAS4; neuronal PAS domain-containing protein 4
K02223 CLOCK, KAT13D; circadian locomoter output cycles kaput protein [EC:2.3.1.48]
K02296 ARNTL, BMAL1, CYC; aryl hydrocarbon receptor nuclear translocator-like protein 1
K09099 ARNTL2, BMAL2; aryl hydrocarbon receptor nuclear translocator-like protein 2
K09100 SIM; single-minded
K25796 YAB; plant-specific transcription factor YABBY family protein
K09102 INO; heteromeric Ino2p/Ino4p transcription factor
K04680 ID1; DNA-binding protein inhibitor ID1
K17693 ID2; DNA-binding protein inhibitor ID2
K17694 ID3; DNA-binding protein inhibitor ID3
K17695 ID4; DNA-binding protein inhibitor ID4
K17696 EMC; DNA-binding protein inhibitor ID, other
K09103 EBF, COE; early B-cell factor
K21626 CCNDBP1, DIP1, GCIP; cyclin-D1-binding protein 1
K22495 SOHLH1; spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1
K12126 PIF3; phytochrome-interacting factor 3
K16189 PIF4; phytochrome-interacting factor 4
K13422 MYC2; transcription factor MYC2
K20558 SPCH; transcription factor SPEECHLESS
K26213 FAMA; transcription factor FAMA
K26214 FIT; transcription factor FER-LIKE IRON
K09104 TX; delilah
K22484 CBF1; transcriptional regulator CBF1
K09105 TFE3; transcription factor E3
K15590 TFEB; transcription factor EB
K15591 TFEC; transcription factor EC
K09455 MITF; microphthalmia-associated transcription factor
K09106 USF; upstream stimulatory factor
K07197 SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
K09107 SREBP2, SREBF2; sterol regulatory element-binding transcription factor 2
K09108 TFAP4; transcription factor AP-4
K04377 MYC; Myc proto-oncogene protein
K09109 NMYC, MYCN; N-myc proto-oncogene protein
K09110 LMYC, MYCL; L-myc proto-oncogene protein
K09111 BMYC, MYCB; brain expressed myelocytomatosis oncogene
K09112 SMYC, MYCS; myc-like oncogene
K04453 MAX; Max protein
K09113 MLX; MAX-like protein X
K09114 MXD, MAD; MAX dimerization protein
K09115 MNT, ROX; MAX-binding protein
K17482 SPZ1; spermatogenic leucine zipper protein 1
K09168 NFIA; nuclear factor I/A
K09169 NFIB; nuclear factor I/B
K09170 NFIC; nuclear factor I/C
K09171 NFIX; nuclear factor I/X
K09172 NFIN; nuclear factor I, invertebrate
K09173 RFX1_2_3; regulatory factor X 1/2/3
K09174 RFX4; regulatory factor X 4
K08061 RFX5; regulatory factor X 5
K19521 RFX6; regulatory factor X 6
K09175 RFX7; DNA-binding protein RFX7
K09176 TFAP2A_B; transcription factor AP-2 alpha/beta
K09177 TFAP2C; transcription factor AP-2 gamma
K09178 TFAP2D; transcription factor AP-2 delta
K09179 TFAP2E; transcription factor AP-2 epsilon
K09180 TFAP2N; transcription factor AP-2, invertebrate
K05547 THRA, NR1A1; thyroid hormone receptor alpha
K08362 THRB, NR1A2; thyroid hormone receptor beta
K08527 RARA, NR1B1; retinoic acid receptor alpha
K08528 RARB, NR1B2; retinoic acid receptor beta
K08529 RARG, NR1B3; retinoic acid receptor gamma
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K03728 NR1D1; nuclear receptor subfamily 1 group D member 1
K08531 NR1D2; nuclear receptor subfamily 1 group D member 2
K08701 NR1D3; nuclear receptor subfamily 1 group D member 3
K08532 NR1F1, RORA; RAR-related orphan receptor alpha
K08533 NR1F2, RORB; RAR-related orphan receptor beta
K08534 NR1F3, RORC; RAR-related orphan receptor gamma
K14033 NR1F4; nuclear receptor subfamily 1 group F member 4
K08536 NR1H3, LXRA; liver X receptor alpha
K08535 NR1H2, LXRB; liver X receptor beta
K08537 NR1H4, FXR; farnesoid X receptor
K08538 NR1H5, FXRB; farnesoid X receptor beta
K14034 NR1H1, EcR; ecdysone receptor
K08539 VDR, NR1I1; vitamin D3 receptor
K08540 NR1I2, PXR; pregnane X receptor
K08541 NR1I3, CAR; constitutive androstane receptor
K14035 NR1IN; nuclear receptor subfamily 1 group I
K07292 NR2A1, HNF4A; hepatocyte nuclear factor 4-alpha
K08037 NR2A2, HNF4G; hepatocyte nuclear factor 4-gamma
K08542 NR2A3, HNF4B; hepatocyte nuclear factor 4-beta
K08704 NR2A4, Hnf4; hepatocyte nuclear factor 4
K07295 NR2AN, dsf; nuclear receptor subfamily 2 group A
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K14030 NR2B4, usp; nuclear receptor subfamily 2 group B member 4
K08543 NR2C1, TR2; testicular receptor 2
K08544 NR2C2, TR4; testicular receptor 4
K14031 NR2CN; nuclear receptor subfamily 2 group C
K08545 NR2E1, TLX, tll; nuclear receptor subfamily 2 group E member 1
K08546 NR2E3, PNR; nuclear receptor subfamily 2 group E member 3
K08547 NR2F1, TFCOUP1; COUP transcription factor 1
K08548 NR2F2, TFCOUP2; COUP transcription factor 2
K14032 NR2F3, svp; nuclear receptor subfamily 2 group F member 3
K08702 NR2F5, SVP46; nuclear receptor subfamily 2 group F member 5
K08549 NR2F6, EAR2; nuclear receptor subfamily 2 group F member 6
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K08552 NR3B1, ESRRA; estrogen-related receptor alpha
K08553 NR3B2, ESRRB; estrogen-related receptor beta
K08554 NR3B3, ESRRG; estrogen-related receptor gamma
K08703 NR3BN, ERR; estrogen-related receptor ERR
K05771 NR3C1, GR; glucocorticoid receptor
K08555 NR3C2, MR; mineralocorticoid receptor
K08556 PGR, NR3C3; progesterone receptor
K08557 AR, NR3C4; androgen receptor
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K08558 NR4A2, NURR1; nuclear receptor subfamily 4 group A member 2
K08559 NR4A3, NOR1; nuclear receptor subfamily 4 group A member 3
K08560 NR5A1, SF1; steroidogenic factor 1
K08027 NR5A2, FTF; nuclear receptor subfamily 5 group A member 2
K08705 NR5A3, ftz-f1; nuclear receptor subfamily 5 group A member 3
K08561 NR6A1, GCNF; germ cell nuclear factor
K09185 NR6AN; nuclear receptor subfamily 6 group A
K08706 NR0AN, kni; nuclear receptor subfamily 0 group A
K08562 NR0B1, DAX1; nuclear receptor subfamily 0 group B member 1
K08563 NR0B2, SHP; nuclear receptor subfamily 0 group B member 2
K09182 GATA1; GATA-binding protein 1
K17894 GATA2; GATA-binding protein 2
K17895 GATA3; GATA-binding protein 3
K09183 GATA4; GATA-binding protein 4
K17896 GATA5; GATA-binding protein 5
K17897 GATA6; GATA-binding protein 6
K09184 GATAF; GATA-binding protein, other eukaryote
K21630 ZGLP1; GATA-type zinc finger protein 1
K22040 TRPS1; atypical GATA-binding protein TRPS1
K23407 GATAD1; GATA zinc finger domain-containing protein 1
K23194 GATAD2; transcriptional repressor p66
K05628 RERE; arginine-glutamic acid dipeptide repeats protein
K11660 MTA; metastasis-associated protein MTA
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K17400 DNMT3L; DNA (cytosine-5)-methyltransferase 3-like
K10779 ATRX; transcriptional regulator ATRX
K18658 ASH1; transcriptional regulatory protein ASH1
K04684 SP1; transcription factor Sp1
K09192 SP2; transcription factor Sp2
K09193 SP3; transcription factor Sp3
K09194 SP4; transcription factor Sp4
K09195 SP5; transcription factor Sp5
K09196 SP6; transcription factor Sp6
K09197 SP7; transcription factor Sp7
K09198 SP8; transcription factor Sp8
K09199 SP9; transcription factor Sp9
K09200 SP-N; transcription factor Sp, invertebrate
K09204 KLF1; krueppel-like factor 1
K17845 KLF2; krueppel-like factor 2
K15605 KLF3; krueppel-like factor 3
K17846 KLF4; krueppel-like factor 4
K09206 KLF5; krueppel-like factor 5
K09207 KLF6_7; krueppel-like factor 6/7
K09205 KLF8_12; krueppel-like factor 8/12
K09208 KLF9S, BTEB; krueppel-like factor 9/13/14/16
K09209 KLF10_11, TIEG; krueppel-like factor 10/11
K09210 KLF15; krueppel-like factor 15
K09211 KLF17; krueppel-like factor 17
K09203 EGR1; early growth response protein 1
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K12498 EGR4; early growth response protein 4
K09202 SWI5; regulatory protein SWI5
K09234 WT1; Wilms tumor protein 1
K12379 HKB; huckebein
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K09232 GLIS1_3; zinc finger protein GLIS1/3
K09233 GLIS2; zinc finger protein GLIS2
K09224 ZIC1; zinc finger protein ZIC 1
K06235 ZIC2; zinc finger protein ZIC 2
K18487 ZIC3; zinc finger protein ZIC 3
K09225 ZIC4; zinc finger protein ZIC 4
K09226 ZIC5; zinc finger protein ZIC 5
K09227 ZICN; zinc finger protein ZIC, invertebrate
K16799 CI; transcriptional activator cubitus interruptus
K05707 SNAI1; snail 1
K05706 SNAI2, SLUG; snail 2
K09217 SNAI3; snail 3
K09219 SCRT; scratch
K25795 INSM; insulinoma-associated protein
K10488 ZBTB1; zinc finger and BTB domain-containing protein 1
K10489 ZBTB2; zinc finger and BTB domain-containing protein 2
K10490 ZBTB3; zinc finger and BTB domain-containing protein 3
K10491 ZBTB4; zinc finger and BTB domain-containing protein 4
K10492 ZBTB5; zinc finger and BTB domain-containing protein 5
K10493 ZBTB6; zinc finger and BTB domain-containing protein 6
K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
K10496 ZBTB9; zinc finger and BTB domain-containing protein 9
K10497 ZBTB10, RINZF; zinc finger and BTB domain-containing protein 10
K10498 ZBTB11; zinc finger and BTB domain-containing protein 11
K10499 ZBTB12; zinc finger and BTB domain-containing protein 12
K24804 ZBTB14; zinc finger and BTB domain-containing protein 14
K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K10500 ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
K10501 ZBTB20, HOF, DPZF; zinc finger and BTB domain-containing protein 20
K24805 ZBTB21; zinc finger and BTB domain-containing protein 21
K10502 ZBTB22, BING1; zinc finger and BTB domain-containing protein 22
K10503 ZBTB24, BIF1; zinc finger and BTB domain-containing protein 24
K10504 ZBTB25; zinc finger and BTB domain-containing protein 25
K10505 ZBTB26; zinc finger and BTB domain-containing protein 26
K10506 ZBTB32, TZFP; zinc finger and BTB domain-containing protein 32
K10507 ZBTB33, KAISO; zinc finger and BTB domain-containing protein 33
K10508 ZBTB34; zinc finger and BTB domain-containing protein 34
K24806 ZBTB35, ZNF131; zinc finger and BTB domain-containing protein 35
K10509 ZBTB37; zinc finger and BTB domain-containing protein 37
K10510 ZBTB38; zinc finger and BTB domain-containing protein 38
K10511 ZBTB39; zinc finger and BTB domain-containing protein 39
K10512 ZBTB40; zinc finger and BTB domain-containing protein 40
K10513 ZBTB41; zinc finger and BTB domain-containing protein 41
K10514 ZBTB43; zinc finger and BTB domain-containing protein 43
K10515 ZBTB44, BTBD15; zinc finger and BTB domain-containing protein 44
K10516 ZBTB45; zinc finger and BTB domain-containing protein 45
K10517 ZBTB46, BTBD4; zinc finger and BTB domain-containing protein 46
K10518 ZBTB47; zinc finger and BTB domain-containing protein 47
K10519 ZBTB48, HKR3; zinc finger and BTB domain-containing protein 48
K24807 ZBTB49; zinc finger and BTB domain-containing protein 49
K23196 ZBTB18_42; zinc finger and BTB domain-containing protein 18/42
K22402 GZF1; GDNF-inducible zinc finger protein 1
K15618 BCL6; B-cell lymphoma 6 protein
K22648 BCL6B; B-cell CLL/lymphoma 6 member B protein
K24383 PATZ1; POZ-AT hook zinc finger protein 1
K26610 VEZF1; vascular endothelial zinc finger 1
K24384 HIC; hypermethylated in cancer protein
K24385 MYNN; myoneurin
K09237 TTK; tramtrack
K02174 BR-C; broad-complex core protein
K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
K24638 ZBED2; zinc finger BED domain-containing protein 2
K24639 ZBED3; zinc finger BED domain-containing protein 3
K24640 ZBED4; zinc finger BED domain-containing protein 4
K24641 ZBED6; zinc finger BED domain-containing protein 6
K24501 PRDM1; PR domain zinc finger protein 1 [EC:2.1.1.-]
K11432 PRDM2, RIZ; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K12463 PRDM4; PR domain zinc finger protein 4 [EC:2.1.1.-]
K22534 PRDM5; PR domain zinc finger protein 5 [EC:2.1.1.-]
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361]
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K24643 PRDM10; PR domain zinc finger protein 10 [EC:2.1.1.-]
K24644 PRDM11; PR domain zinc finger protein 11 [EC:2.1.1.-]
K24645 PRDM13; PR domain zinc finger protein 13 [EC:2.1.1.-]
K24646 PRDM14; PR domain zinc finger protein 14 [EC:2.1.1.-]
K24647 PRDM15; PR domain zinc finger protein 15 [EC:2.1.1.-]
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367]
K09238 ACE2; metallothionein expression activator
K09466 ADR1; zinc finger protein ADR1
K09467 MIG; zinc-finger protein CreA/MIG
K09468 MSN2_4; zinc finger protein MSN2/4
K19798 GIS1; transcriptional activator/repressor GIS1
K19799 RPH1; DNA damage-responsive transcriptional repressor / [histone H3]-trimethyl-L-lysine36 demethylase [EC:1.14.11.69]
K09215 OSR, ODD; odd-skipped
K09216 OVOL; ovo
K09220 IKZF, ZNFN1A; IKAROS family zinc finger protein
K09221 MZF1; myeloid zinc finger protein 1
K09222 REST; RE1-silencing transcription factor
K09223 GFI1; growth factor independent 1
K09236 TSHZ; teashirt
K09239 HIVEP; human immunodeficiency virus type I enhancer-binding protein
K17452 AEBP2; zinc finger protein AEBP2
K19484 PLAG1; zinc finger protein PLAG1
K19485 PLAGL1; zinc finger protein PLAGL1
K19486 PLAGL2; zinc finger protein PLAGL2
K20210 RREB1; ras-responsive element-binding protein 1
K22045 BCL11A; B-cell lymphoma/leukemia 11A
K22046 BCL11B; B-cell lymphoma/leukemia 11B
K22401 E4F1; transcription factor E4F1 / E3 ubiquitin-protein ligase [EC:2.3.2.27]
K23195 CTCF, CTCFL; transcriptional repressor CTCF
K23317 MTF1; metal regulatory transcription factor 1
K24146 BNC; zinc finger protein basonuclin
K09191 GTF3A; general transcription factor IIIA
K09201 YY; transcription factor YY
K07466 RFA1, RPA1, rpa; replication factor A1
K26101 ZNF16, HZF1; zinc finger protein 16
K24851 ZNF142; zinc finger protein 142
K24370 ZNF148; zinc finger protein 148
K27241 ZNF219; zinc finger protein 219
K12458 ZNF274; zinc finger protein 274
K26728 ZNF292; zinc finger protein 292
K24371 ZNF335; zinc finger protein 335
K24852 ZNF341; zinc finger protein 341
K23480 ZNF362_384, LIN-29; zinc finger protein 362/384
K26729 ZNF407; Zinc finger protein 407
K24372 ZNF408; zinc finger protein 408
K25858 ZNF410; zinc finger protein 410
K22870 ZNF423; zinc finger protein 423
K24853 ZNF462; zinc finger protein 462
K24373 ZNF513; zinc finger protein 513
K22411 ZNF516; zinc finger protein 516
K24916 ZNF521, EVI3; zinc finger protein 521
K26978 ZNF526_574; zinc finger protein 526/574
K27242 ZNF536; zinc finger protein 536
K24692 ZNF638; zinc finger protein 638
K24374 ZNF644; zinc finger protein 644
K27106 ZNF668; zinc finger protein 668
K24375 ZNF687; zinc finger protein 687
K24376 ZNF711; zinc finger protein 711
K24377 ZNF750; zinc finger protein 750
K09228 KRAB; KRAB domain-containing zinc finger protein
K09229 ZKSCAN; KRAB and SCAN domains-containing zinc finger protein
K09230 SCAN; SCAN domain-containing zinc finger protein
K24502 FEZF; Fez family zinc finger protein
K25209 CASZ1; zinc finger protein castor
K25794 HINFP; histone H4 transcription factor
K09231 KR; krueppel
K13943 CBT; cabut
K09213 HB; hunchback
K09214 GL; glass
K02215 CF2; chorion factor 2
K22535 DRM; drumstick
K25869 IDD1_2; zinc finger protein IDD1/2
K25870 IDD3S; zinc finger protein IDD3/4/5/6/7/8/9/10/11/12/13
K25871 IDD14_15_16; zinc finger protein IDD14/15/16
K09235 RME1; zinc finger protein RME1
K09465 BRLA; zinc finger protein BrlA
K19487 SFP1; transcription factor SFP1
K22412 SDC-1; zinc finger protein Sdc-1
K21455 CON7; transcription factor CON7
K21543 CRZ1, CRZA; transcription factor CRZ1
K21544 NSF1, BCR1, DVRA; C2H2 transcription facotor
K21545 MNL1, SEB1, SEBA, COM2; C2H2 transcription facotor
K21597 CAS5; cell wall integrity transcriptional regulator CAS5
K23192 MYT1; myelin transcription factor 1
K23193 MYT1L; myelin transcription factor 1-like protein
K24386 ST18; suppression of tumorigenicity 18 protein
K17441 ZFPM1, FOG1; zinc finger protein ZFPM1
K17442 ZFPM2, FOG2; zinc finger protein ZFPM2
K11308 MYST1, MOF, KAT8; histone acetyltransferase MYST1 [EC:2.3.1.48]
K11307 MYST2, HBO1, KAT7; histone acetyltransferase MYST2 [EC:2.3.1.48]
K11305 MYST3, KAT6A; histone acetyltransferase MYST3 [EC:2.3.1.48]
K11306 MYST4, KAT6B; histone acetyltransferase MYST4 [EC:2.3.1.48]
K11304 TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
K24387 L3MBTL; lethal(3)malignant brain tumor-like protein
K15263 LYER; cell growth-regulating nucleolar protein
K24388 ZC3H8; zinc finger CCCH domain-containing protein 8
K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
K10643 CNOT4, NOT4, MOT2; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
K23203 THAP1_3; THAP domain-containing protein 1/3
K23206 THAP5_8; THAP domain-containing protein 5/8
K23208 THAP7; THAP domain-containing protein 7
K23210 THAP10; THAP domain-containing protein 10
K23211 THAP11; THAP domain-containing protein 11
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
K14960 CXXC1, SPP1, CPS40; COMPASS component SPP1
K22760 CXXC5; CXXC-type zinc finger protein 5
K13097 TET1; methylcytosine dioxygenase [EC:1.14.11.80]
K24309 TET2_3; methylcytosine dioxygenase TET2/3 [EC:1.14.11.80]
K00558 DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K10276 FBXL10_11, KDM2; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
K10285 FBXL19; F-box and leucine-rich repeat protein 19
K11589 MBD1; methyl-CpG-binding domain protein 1
K03344 IDAX; Dvl-binding protein IDAX
K09240 CAT8; transcriptional regulatory protein CAT8
K27389 RDS2, ERT1, GSM1; transcription activator of gluconeogenesis
K09241 GAL4; transcriptional regulatory protein GAL4
K09242 LEU3; transcriptional regulatory protein LEU3
K09243 UME6; transcriptional regulatory protein UME6
K09244 AMDR; transcriptional regulatory protein AMDR
K09245 UGA3; transcriptional activator protein UGA3
K09246 ARG81, ARGR2; arginine metabolism regulation protein II
K09247 CYP1, HAP1; heme activator protein 1
K09248 PUT3; proline utilization trans-activator
K21641 RGT1; glucose transport transcription regulator RGT1
K21546 GLIZ; C6 transcription factor GliZ
K21450 ARAR; arabinolytic transcriptional activator AraR
K23629 ASAR; C6 transcription factor AsaR
K21547 PRO1, NOSA; C6 transcription factor Pro1
K21632 WOR2; white-opaque regulator 2
K21633 CZF1; zinc cluster transcription factor CZF1
K11467 PHF1, PCL1; PHD finger protein 1
K23310 PHF6; PHD finger protein 6
K11486 PHF19, PCL3; PHD finger protein 19
K26271 MS1, MMD1; PHD finger protein MS1/MMD1
K26274 AL; PHD finger protein ALFIN-LIKE
K11485 MTF2, PCL2; metal regulatory transcription factor 2
K12236 NFX1; transcriptional repressor NF-X1
K19749 RAI1; retinoic acid-induced protein 1
K09250 CNBP; cellular nucleic acid-binding protein
K24369 ZC4H2; zinc finger C4H2 domain-contaning protein
K24769 TCF20; transcription factor 20
K22383 IRF2BP; interferon regulatory factor 2-binding protein
K27448 IRF2BP2; interferon regulatory factor 2-binding protein 2
K09249 ABF1, BAF1; ARS-binding factor 1
K21950 HOXA9; homeobox protein Hox-A9
K09294 HOX_9; homeobox protein HoxB/C/D9
K17443 HOXA10; homrobox protein Hox-A10
K17444 HOXC10; homrobox protein Hox-C10
K09295 HOXD10; homrobox protein Hox-D10
K21951 HOXA11; homeobox protein Hox-A11
K09296 HOX_11; homeobox protein HoxC/D11
K09297 HOX_12; homeobox protein HoxC/D12
K09298 HOX_13; homeobox protein HoxA/B/C/D13
K09301 HOX_1; homeobox protein HoxA/B/D1
K09302 HOX_2; homeobox protein HoxA/B2
K09303 HOX_3; homeobox protein HoxA/B/D3
K09304 HOX_4; homeobox protein HoxA/B/C/D4
K09305 HOX_5; homeobox protein HoxA/B/C5
K09306 HOX_6; homeobox protein HoxA/B/C6
K09307 HOX_7; homeobox protein HoxA/B7
K09308 HOX_8; homeobox protein HoxB/C/D8
K09310 GSH; homeobox protein GSH
K07594 IPF1, PDX1; insulin promoter factor 1
K09312 CDX1_4; homeobox protein CDX1/4
K22234 CDX2; homeobox protein CDX2
K09320 EVX; homeobox even-skipped homolog protein
K09321 GBX; homeobox protein GBX
K08025 HLXB9, HB9; homeobox protein HB9
K09322 MEOX, MOX; homeobox protein MOX
K09300 ABDB; homeobox protein abdominal-B and related proteins
K18659 BCD; homeotic protein bicoid
K09309 NKX1; homeobox protein Nkx-1
K09342 NKX2-1, TITF1; homeobox protein Nkx-2.1
K08029 NKX2-2; homeobox protein Nkx-2.2
K09343 NKX2-3; homeobox protein Nkx-2.3
K09344 NKX2-4; homeobox protein Nkx-2.4
K09345 NKX2-5; homeobox protein Nkx-2.5
K09346 NKX2-6; homeobox protein Nkx-2.6
K09347 NKX2-8; homeobox protein Nkx-2.8
K09348 NKX3-1; homeobox protein Nkx-3.1
K09995 NKX3-2, BAPX1; homeobox protein Nkx-3.2
K09349 NKX5, HMX; homeobox protein Nkx-5
K08030 NKX6-1; homeobox protein Nkx-6.1
K09350 NKX6-2; homeobox protein Nkx-6.2
K09351 NKX6-3; homeobox protein Nkx-6.3
K09352 NKXN; homeobox protein Nkx, invertebrate
K09314 DLX1_4_6; homeobox protein DLX1/4/6
K18488 DLX2; homeobox protein DLX2
K09315 DLX3; homeobox protein DLX3
K18489 DLX5; homeobox protein DLX5
K09340 TLX1, HOX11; T-cell leukemia homeobox protein 1
K15606 TLX2, HOX11L1; T-cell leukemia homeobox protein 2
K15607 TLX3, HOX11L2; T-cell leukemia homeobox protein 3
K09339 HLX1; homeobox protein HLX1
K09317 EMX; homeobox protein EMX
K09318 VAX; homeobox protein ventral anterior
K09319 EN; homeobox protein engrailed
K09341 MSX; homeobox protein MSX
K09353 LBX; homeobox protein LBX
K08024 HHEX, HEX, PRH; homeobox protein HEX
K09360 BARHL; BarH-like
K09361 BARX; BarH-like homeobox
K10164 NANOG; homeobox protein Nanog
K24874 BSX; brain-specific homeobox protein
K24875 DBX; homeobox protein DBX
K24876 NOTO; homeobox protein notochord
K24877 VENTX; homeobox protein VENTX
K09452 ARX; homeobox protein aristaless-related
K09323 ALX3; homeobox protein aristaless-like 3
K09451 ALX4; homeobox protein aristaless-like 4
K09324 GSC; homeobox protein goosecoid
K09325 GSCL; homeobox protein goosecoid-like
K09326 OTX1; homeobox protein OTX1
K18490 OTX2; homeobox protein OTX2
K09327 PROP1; homeobox protein prophet of Pit-1
K09328 UNC4; homeobox protein Unc-4
K09329 PRRX, PMX; paired mesoderm homeobox protein
K09330 PHOX2, PMX2; paired mesoderm homeobox protein 2
K09331 SHOX; short stature homeobox protein
K09332 RAX, RX; retina and anterior neural fold homeobox protein
K09333 RAXL; retina and anterior neural fold homeobox-like protein
K09334 ALX1, CART1; ALX homeobox protein 1
K09335 VSX1; visual system homeobox protein 1
K09336 VSX2, CHX10; visual system homeobox protein 2
K09337 CRX; cone-rod homeobox protein
K18491 ESX1; homeobox protein ESX1
K24199 NOBOX; homeobox protein NOBOX
K09356 PITX1; paired-like homeodomain transcription factor 1
K04686 PITX2; paired-like homeodomain transcription factor 2
K09357 PITX3; paired-like homeodomain transcription factor 3
K09354 HESX1; homeobox protein expressed in ES cells 1
K24892 ARGFX; arginine-fifty homeobox
K24893 DMBX1; diencephalon/mesencephalon homeobox protein 1
K24894 DPRX; divergent paired-related homeobox
K24895 DRGX, PRRXL1; dorsal root ganglia homeobox protein
K24896 DUX; double homeobox protein
K24897 HOPX; homeodomain-only protein
K24898 ISX; intestine-specific homeobox
K24899 LEUTX; leucine-twenty homeobox
K24900 MIXL1; homeobox protein MIXL1
K24901 OTP; homeobox protein orthopedia
K24902 RHOXF1; rhox homeobox family member 1
K24903 RHOXF2; rhox homeobox family member 2
K24904 SEBOX; homeobox protein SEBOX
K24905 TPRX1; tetra-peptide repeat homeobox protein 1
K09382 PAX1_9; paired box protein 1/9
K15608 PAX2; paired box protein 2
K09381 PAX3_7; paired box protein 3/7
K08032 PAX4; paired box protein 4
K09383 PAX5; paired box protein 5
K08031 PAX6; paired box protein 6
K09293 PAX8; paired box protein 8
K09370 ISL1; insulin gene enhancer protein ISL-1
K18492 ISL2; insulin gene enhancer protein ISL-2
K09371 LMX1; LIM homeobox transcription factor 1
K09372 LHX1; LIM homeobox protein 1
K09373 LHX2_9; LIM homeobox protein 2/9
K09374 LHX3_4; LIM homeobox protein 3/4
K18493 LHX5; LIM homeobox protein 5
K09375 LHX6_8; LIM homeobox protein 6/8
K09377 CSRP; cysteine and glycine-rich protein
K09363 POU1F, PIT1; POU domain transcription factor, class 1
K09364 POU2F, OTF; POU domain transcription factor, class 2
K09365 POU3F, OTF; POU domain transcription factor, class 3
K09366 POU4F, BRN3; POU domain transcription factor, class 4
K09367 POU5F; POU domain transcription factor, class 5
K09368 POU6F; POU domain transcription factor, class 6
K24884 HDX; highly divergent homeobox
K08036 TCF1, HNF1A; transcription factor 1, hepatocyte nuclear factor 1-alpha
K08034 TCF2, HNF1B; transcription factor 2, hepatocyte nuclear factor 1-beta
K24885 HMBOX1; homeobox-containing protein 1
K15614 SIX1; homeobox protein SIX1
K19472 SIX2; homeobox protein SIX2
K19473 SIX3_6, OPTIX; homeobox protein SIX3/6
K15615 SIX4; homeobox protein SIX4
K19474 SIX5; homeobox protein SIX5
K09379 ZFHX2; zinc finger homeobox protein 2
K09378 ZFHX3, ATBF1; zinc finger homeobox protein 3
K09380 ZFHX4; zinc finger homeobox protein 4
K09299 ZEB1; zinc finger homeobox protein 1
K23560 ZEB2; zinc finger homeobox protein 2
K22591 ADNP; activity-dependent neuroprotector homeobox protein
K24878 ADNP2; activity-dependent neuroprotector homeobox protein 2
K24879 ZHX1; zinc fingers and homeoboxes protein 1
K24880 ZHX2; zinc fingers and homeoboxes protein 2
K24881 ZHX3; zinc fingers and homeoboxes protein 3
K24883 HOMEZ; homeobox and leucine zipper protein Homez
K24882 NANOGNB; NANOG neighbor homeobox
K09313 CUTL; homeobox protein cut-like
K08026 ONECUT1, HNF6; one cut domain, family member 1 (hepatocyte nuclear factor 6)
K24170 ONECUT2; one cut domain family member 2
K24171 ONECUT3; one cut domain family member 3
K23225 SATB1; DNA-binding protein SATB1
K23226 SATB2; DNA-binding protein SATB2
K20211 PROX1; prospero homeobox 1
K20212 PROX2; prospero homeobox 2
K09355 PBX1; pre-B-cell leukemia transcription factor 1
K15609 PBX2; pre-B-cell leukemia transcription factor 2
K15610 PBX3; pre-B-cell leukemia transcription factor 3
K15611 PBX4; pre-B-cell leukemia transcription factor 4
K15613 MEIS1; homeobox protein Meis1
K16670 MEIS2; homeobox protein Meis2
K16671 MEIS3; homeobox protein Meis3
K19383 TGIF1; homeobox protein TGIF1
K19553 TGIF2; homeobox protein TGIF2
K19554 TGIF2L, TGIFL; homeobox protein TGIF2L
K24889 IRX; iroquois-class homeodomain protein IRX
K24890 MKX; homeobox protein Mohawk
K24891 PKNOX; homeobox protein PKNOX
K16672 HTH; homeobox protein homothorax
K09359 MATA2; mating-type protein A2
K22536 DAN, DANR; distal antenna
K09338 HD-ZIP; homeobox-leucine zipper protein
K09358 MATA1; mating-type protein A1
K02646 PHO2; regulatory protein PHO2
K12411 YOX1, YHP1; homeobox protein YOX1/YHP1
K09362 K09362; homeo domain only family, other
K08035 FOXA2, HNF3B; forkhead box protein A2, hepatocyte nuclear factor 3-beta
K09396 FOXC; forkhead box protein C
K09385 FOXG; forkhead box protein G
K09407 FOXN; forkhead box protein N
K09387 FOXA1, HNF3A; forkhead box protein A1, hepatocyte nuclear factor 3-alpha
K08038 FOXA3, HNF3G; forkhead box protein A3, hepatocyte nuclear factor 3-gamma
K09402 FOXJ1; forkhead box protein J1
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K09390 E2F6; transcription factor E2F6
K09391 E2F7_8; transcription factor E2F7/8
K04683 TFDP1; transcription factor Dp-1
K09392 TFDP2; transcription factor Dp-2
K09393 TFDP3; transcription factor Dp-3
K09395 FOXB; forkhead box protein B
K09397 FOXD; forkhead box protein D
K09398 FOXE; forkhead box protein E
K09399 FOXF; forkhead box protein F
K09400 FOXH; forkhead box protein H
K09401 FOXI; forkhead box protein I
K09403 FOXJ2_3; forkhead box protein J2/3
K09404 FOXK; forkhead box protein K
K09405 FOXL; forkhead box protein L
K09406 FOXM; forkhead box protein M
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K23582 FOXP1; forkhead box protein P1
K09409 FOXP2_4; forkhead box protein P2/4
K10163 FOXP3, IPEX; forkhead box P3
K09410 FOXQ, HFH1; forkhead box protein Q
K26215 FOXR; forkhead box protein R
K09412 FOXS; forkhead box protein S
K09411 FOXX; forkhead box protein, other
K09413 HCM1; forkhead transcription factor HCM1
K24664 FKH; forkhead protein FKH
K09414 HSF1; heat shock transcription factor 1
K09415 HSF2; heat shock transcription factor 2
K09416 HSF3; heat shock transcription factor 3
K09417 HSF4; heat shock transcription factor 4
K09419 HSFF; heat shock transcription factor, other eukaryote
K09420 MYB, C-MYB; transcriptional activator Myb
K09421 MYBL1, A-MYB; myb-related protein A
K21769 MYBL2, B-MYB; myb-related protein B
K09422 MYBP; transcription factor MYB, plant
K23865 MYB30; transcription factor MYB30
K16166 PAP1, MYB75; transcription factor MYB75
K12133 LHY; MYB-related transcription factor LHY
K12134 CCA1; circadian clock associated 1
K09453 SNAPC4; snRNA-activating protein complex subunit 4
K21625 DMTF1, DMP1; cyclin-D-binding Myb-like transcription factor 1
K09423 BAS1; Myb-like DNA-binding protein BAS1
K09424 REB1; Myb-like DNA-binding protein REB1
K09425 K09425; Myb-like DNA-binding protein FlbD
K09426 RAP1; Myb-like DNA-binding protein RAP1
K09427 ADF1; Adh transcription factor 1
K09428 ELF1_2_4; E74-like factor 1/2/4
K09429 K09429, ELF3; E74-like factor 3
K17101 ELF5; E74-like factor 5
K17102 EHF; ETS homologous factor
K04375 ELK1; ETS domain-containing protein Elk-1
K09430 ELK3; ETS domain-containing protein Elk-3 (SRF accessory protein 2)
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K09431 ETV1; ets translocation variant 1
K09432 ETV2, ER71; ETS translocation variant 2
K09433 ETV3; ETS translocation variant 3
K15592 ETV4; ets translocation variant 4
K15593 ETV5; ets translocation variant 5
K03211 ETV6_7, yan; ETS translocation variant 6/7
K09434 ERF; ETS domain-containing transcription factor ERF
K02678 ETS1, pnt; C-ets-1
K21932 ETS2; C-ets-2
K09435 ERG; transcriptional regulator ERG
K09436 FLI1; friend leukemia integration 1 transcription factor
K09437 FEV; ETS oncogene family protein FEV
K09438 SPI1; transcription factor PU.1
K09439 SPIB; transcription factor Spi-B
K09440 SPIC; transcription factor Spi-C
K09441 GABPA; GA-binding protein transcription factor, alpha
K09442 SPDEF; SAM pointed domain-containing ETS transcription factor
K09443 K09443; ETS-type family, other
K09444 IRF1; interferon regulatory factor 1
K10153 IRF2; interferon regulatory factor 2
K05411 IRF3; interferon regulatory factor 3
K09445 IRF4; interferon regulatory factor 4
K09446 IRF5; interferon regulatory factor 5
K10154 IRF6; interferon regulatory factor 6
K09447 IRF7; interferon regulatory factor 7
K10155 IRF8; interferon regulatory factor 8
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K09448 TEAD; transcriptional enhancer factor
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11765 ARID2; AT-rich interactive domain-containing protein 2
K25856 ARID3; AT-rich interactive domain-containing protein 3
K19194 ARID4A, RBP1; AT-rich interactive domain-containing protein 4A
K19195 ARID4B; AT-rich interactive domain-containing protein 4B
K25857 ARID5; AT-rich interactive domain-containing protein 5
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K09253 RELB; transcription factor RelB
K09254 REL; c-Rel proto-oncogene protein
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K14214 NFKBID; NF-kappa-B inhibitor delta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K14242 NFKBIZ; NF-kappa-B inhibitor zeta
K09256 NFKBIL1; NF-kappa-B inhibitor-like protein 1
K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
K09258 BCL3; B-cell CLL/lymphoma 3 protein
K09454 GABPB; GA-binding protein transcription factor, beta
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K17335 NFAT5; nuclear factor of activated T-cells 5
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K04451 TP53, P53; tumor protein p53
K10148 TP73; tumor protein p73
K10149 TP63; tumor protein p63
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K09261 MEF2B; MADS-box transcription enhancer factor 2B
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K09262 MEF2D; MADS-box transcription enhancer factor 2D
K09264 K09264; MADS-box transcription factor, plant
K12412 MCM1; pheromone receptor transcription factor
K19808 ARG80, ARGR1; arginine metabolism regulation protein I
K09265 RLM1; transcription factor RLM1
K19807 SMP1; transcription factor SMP1
K04378 SRF; serum response factor
K15413 SP100; nuclear body protein Sp100
K24503 SP110; nuclear body protein Sp110
K24504 SP140; nuclear body protein Sp140
K10603 AIRE; autoimmune regulator
K23041 DEAF1; deformed epidermal autoregulatory factor 1
K24505 GMEB; glucocorticoid modulatory element-binding protein
K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
K09266 SRY; sex-determining region Y protein (SOX group A)
K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
K16796 SOX2; transcription factor SOX2 (SOX group B)
K23581 SOX4; transcription factor SOX4 (SOX group C)
K09268 SOX11_12; transcription factor SOX11/12 (SOX group C)
K09269 SOX5_6_13; transcription factor SOX5/6/13 (SOX group D)
K09270 SOX7S; transcription factor SOX7/8/10/18 (SOX group E/F)
K18435 SOX9; transcription factor SOX9 (SOX group E)
K04495 SOX17; transcription factor SOX17 (SOX group F)
K09271 SOX15_30; transcription factor SOX15/30
K20225 CIC; capicua transcriptional repressor
K21643 BBX, HBP2; HMG box transcription factor BBX
K21644 HBP1; HMG box transcription factor 1
K04492 LEF1; lymphoid enhancer-binding factor 1
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K09272 SSRP1, POB3; FACT complex subunit SSRP1/POB3
K09273 UBTF; upstream-binding transcription factor
K22483 HMO1; transcriptional regulator HMO1
K22496 RFG1, ROX1; repressor RFG1/ROX1
K09274 K09274; HMG box factor, other
K08064 NFYA, HAP2; nuclear transcription factor Y, alpha
K08065 NFYB, HAP3; nuclear transcription Y subunit beta
K08066 NFYC, HAP5; nuclear transcription factor Y, gamma
K09275 TFCP2; transcription factor CP2 and related proteins
K06099 CSDA, ZONAB; cold shock domain protein A
K09276 YBX1, NSEP1; Y-box-binding protein 1
K09277 YBX2; Y-box-binding protein 2
K08367 RUNX1, AML1; runt-related transcription factor 1
K09278 RUNX2, AML3; runt-related transcription factor 2
K09279 RUNX3, AML2; runt-related transcription factor 3
K20213 RUN; RUNX transcription factor Runt
K20214 LZ; RUNX transcription factor Lozenge
K09280 RUNXA_B; runt-related transcription factor
K24768 MYRF; myelin regulatory factor [EC:3.4.-.-]
K12769 NDT80; meiosis-specific transcription factor NDT80
K09282 HMGA1; high mobility group AT-hook protein 1
K09283 HMGA2; high mobility group AT-hook protein 2
K15626 NUPR1, COM1; nuclear protein 1
K25793 NUPR2, NUPR1L; nuclear protein 2
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K10172 BRA, T; brachyury protein
K10173 EOMES, TBR2; eomesodermin protein
K10174 TBR1; T-box brain protein 1
K10175 TBX1; T-box protein 1
K10176 TBX2; T-box protein 2
K10177 TBX3; T-box protein 3
K10178 TBX4; T-box protein 4
K10179 TBX5, HOS; T-box protein 5
K10180 TBX6; T-box protein 6
K10181 TBX10, TBX7; T-box protein 10
K10182 TBX15, TBX14; T-box protein 15
K10183 TBX18; T-box protein 18
K10184 TBX19; T-box protein 19
K10185 TBX20; T-box protein 20
K10166 TBX21; T-box protein 21
K10186 TBX22; T-box protein 22
K19488 DMRT1; doublesex- and mab-3-related transcription factor 1
K19489 DMRT2; doublesex- and mab-3-related transcription factor 2
K19490 DMRT3; doublesex- and mab-3-related transcription factor 3
K19491 DMRT4_5, DMRTA; doublesex- and mab-3-related transcription factor 4/5
K19492 DMRT6, DMRTB; doublesex- and mab-3-related transcription factor 6
K19493 DMRT7, DMRTC2; doublesex- and mab-3-related transcription factor 7
K19494 DMRT8, DMRTC1; doublesex- and mab-3-related transcription factor 8
K26434 LRRFIP; leucine-rich repeat flightless-interacting protein
K16221 TCP21, CHE; transcription factor TCP21 (protein CCA1 HIKING EXPEDITION)
K09284 AP2; AP2-like factor, euAP2 lineage
K09285 OVM, ANT; AP2-like factor, ANT lineage
K09287 RAV; RAV-like factor
K09286 EREBP; EREBP-like factor
K14516 ERF1; ethylene-responsive transcription factor 1
K14517 ERF2; ethylene-responsive transcription factor 2
K14507 ORCA2_3; AP2-domain DNA-binding protein ORCA2/3
K13432 PTI4; pathogenesis-related genes transcriptional activator PTI4
K13433 PTI5; pathogenesis-related genes transcriptional activator PTI5
K13434 PTI6; pathogenesis-related genes transcriptional activator PTI6
K18834 WRKY1; WRKY transcription factor 1
K18835 WRKY2; WRKY transcription factor 2
K13425 WRKY22; WRKY transcription factor 22
K13423 WRKY25; WRKY transcription factor 25
K13426 WRKY29; WRKY transcription factor 29
K13424 WRKY33; WRKY transcription factor 33
K13944 LBD16; LOB domain-containing protein 16
K21994 LBD18; LOB domain-containing protein 18
K13945 LBD29; LOB domain-containing protein 29
K09281 K09281; copper-fist transcription factor
K21404 AKNA; AT-hook-containing transcription factor
K21595 CARF; calcium-responsive transcription factor
K21596 CAMTA; calmodulin-binding transcription activator
K21598 GCM; chorion-specific transcription factor GCM
K21599 CIART, CHRONO, GM129; circadian-associated transcriptional repressor
K22145 TMEM18; transmembrane protein 18
K22543 MN1; transcriptional activator MN1
K22758 CHCHD2; coiled-coil-helix-coiled-coil-helix domain-containing protein 2
K06053 RBPSUH, RBPJK; recombining binding protein suppressor of hairless
K23804 GON4L; GON-4-like protein
K21772 PURA; transcriptional activator protein Pur-alpha
K21799 PURB; transcriptional activator protein Pur-beta
K24992 MYEF2; myelin expression factor 2
K23408 CDCA7, CDCA7L, JPO1; cell division cycle-associated protein 7
K26458 NKRF; NF-kappa-B-repressing factor
K14514 EIN3; ethylene-insensitive protein 3
K11215 STE12; transcription factor STE12
K12413 WHI5; G1-specific transcriptional repressor WHI5
K12764 IME1; meiosis-inducing protein 1
K12779 SUM1; suppressor of MAR1-1 protein
K19815 HOT1; high-osmolarity-induced transcription protein 1
K19816 MSS11; transcription activator MSS11
K21631 GTI1, PAC2, WOR1; Gti1/Pac2 family transcription factor
K12763 EFG1, SOK2; enhanced filamentous growth protein 1
K02099 araC; AraC family transcriptional regulator, arabinose operon regulatory protein
K02508 hpaA; AraC family transcriptional regulator, 4-hydroxyphenylacetate 3-monooxygenase operon regulatory protein
K02854 rhaR; AraC family transcriptional regulator, L-rhamnose operon transcriptional activator RhaR
K02855 rhaS; AraC family transcriptional regulator, L-rhamnose operon regulatory protein RhaS
K03490 chbR, celD; AraC family transcriptional regulator, dual regulator of chb operon
K03755 adiY; AraC family transcriptional regulator, transcriptional activator of adiA
K04033 eutR; AraC family transcriptional regulator, ethanolamine operon transcriptional activator
K05372 ybtA; AraC family transcriptional regulator
K06599 chpD; AraC family transcriptional regulator, chemosensory pili system protein ChpD
K07780 appY; AraC family transcriptional regulator, transcriptional regulator required for anaerobic and stationary phase induction of genes
K10923 tcpN, toxT; AraC family transcriptional regulator, TCP pilus virulence regulatory protein
K11920 envY; AraC family transcriptional regulator
K12243 pchR; AraC family transcriptional regulator, transcriptional activator of the genes for pyochelin and ferripyochelin receptors
K13631 soxS; AraC family transcriptional regulator, mar-sox-rob regulon activator
K13632 marA; AraC family transcriptional regulator, mar-sox-rob regulon activator
K05804 rob; AraC family transcriptional regulator, mar-sox-rob regulon activator
K18325 ramA; AraC family of transcriptional regulator, multidrug resistance transcriptional activator
K14063 feaR; AraC family transcriptional regulator, positive regulator of tynA and feaB
K18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA
K18991 mtrA; AraC family transcriptional regulator, activator of mtrCDE
K19056 tetD; AraC family transcriptional regulator, transposon Tn10 TetD protein
K20968 exsA; AraC family transcriptional regulator, exoenzyme S synthesis regulatory protein ExsA
K21746 rclR; AraC family transcriptional regulator, reactive chlorine species (RCS)-specific activator of rcl operon
K21747 alkR; AraC family transcriptional regulator, alkane utilization regulator
K21906 gadW; AraC family transcriptional regulator, glutamate-dependent acid resistance regulator
K21905 gadX; AraC family transcriptional regulator, glutamate-dependent acid resistance regulator
K23237 melR; AraC family transcriptional regulator, melibiose operon regulatory protein
K25495 nimR; AraC family transcriptional regulator, regulator of nimT
K19693 tfoS; AraC family transcriptional regulator, chitin signaling transcriptional activator
K21701 btr; AraC family transcriptional regulator, transcriptional activator for feuABC-ybbA operon
K27259 pocR; AraC family transcriptional regulator, pdu and cob operon regulator
K13652 K13652; AraC family transcriptional regulator
K13653 K13653; AraC family transcriptional regulator
K07506 K07506; AraC family transcriptional regulator
K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
K13530 adaA; AraC family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]
K13633 ftrA; AraC family transcriptional regulator, transcriptional activator FtrA
K17736 cdhR; AraC family transcriptional regulator, carnitine catabolism transcriptional activator
K21825 argR; AraC family transcriptional regulator, L-arginine-responsive activator
K21826 gbdR; AraC family transcriptional regulator, glycine betaine-responsive activator
K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator
K02521 ilvY; LysR family transcriptional regulator, positive regulator for ilvC
K02623 pcaQ; LysR family transcriptional regulator, pca operon transcriptional activator
K03576 metR; LysR family transcriptional regulator, regulator for metE and metH
K03717 nhaR; LysR family transcriptional regulator, transcriptional activator of nhaA
K04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator
K05596 iciA; LysR family transcriptional regulator, chromosome initiation inhibitor
K05798 leuO; LysR family transcriptional regulator, transcriptional activator for leuABCD operon
K05817 hcaR; LysR family transcriptional regulator, hca operon transcriptional activator
K07592 tdcA; LysR family transcriptional regulator, tdc operon transcriptional activator
K09681 gltC; LysR family transcriptional regulator, transcription activator of glutamate synthase operon
K10918 aphB; LysR family transcriptional regulator, transcriptional activator AphB
K10972 allS; LysR family transcriptional regulator, transcriptional activator of the allD operon
K11921 cynR; LysR family transcriptional regulator, cyn operon transcriptional activator
K13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator
K13635 cbl; LysR family transcriptional regulator, cys regulon transcriptional activator
K13636 dsdC; LysR family transcriptional regulator, D-serine deaminase activator
K13794 tcuR; LysR family transcriptional regulator, regulatory protein for tcuABC
K13928 mdcR; LysR family transcriptional regulator, malonate utilization transcriptional regulator
K14057 abgR; LysR family transcriptional regulator, regulator of abg operon
K14657 nodD; LysR family transcriptional regulator, nod-box dependent transcriptional activator
K25882 syrM; LysR family transcriptional regulator, transcriptional activator of nodD3 and syrA
K16135 dmlR; LysR family transcriptional regulator, transcriptional activator for dmlA
K17737 dhcR; LysR family transcriptional regulator, carnitine catabolism transcriptional activator
K16516 galR; LysR family transcriptional regulator, regulator for genes of the gallate degradation pathway
K17850 ampR; LysR family transcriptional regulator, regulator of gene expression of beta-lactamase
K18297 mexT; LysR family transcriptional regulator, mexEF-oprN operon transcriptional activator
K18900 bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC
K18927 lldR; LysR family transcriptional regulator, L-lactate utilization regulator
K19242 citR; LysR family transcriptional regulator, repressor for citA
K19338 nac; LysR family transcriptional regulator, nitrogen assimilation regulatory protein
K19555 spvR; LysR family transcriptional regulator, spv operon transcriptional activator
K19618 fitG; LysR family transcriptional regulator, activator of insecticidal toxin
K19624 phcA; LysR family transcriptional regulator, virulence genes transcriptional regulator
K19735 mvfR, pqsR; LysR family transcriptional regulator, quorum-sensing system regulator MvfR
K21645 hypT, qseD; LysR family transcriptional regulator, hypochlorite-specific transcription factor HypT
K21698 aaeR; LysR family transcriptional regulator, transcriptional activator for aaeXAB operon
K21699 bauR; LysR family transcriptional regulator, transcriptional activator for bauABCD operon
K21703 cbbR, cmpR, ndhR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator
K21711 pycR; LysR family transcriptional regulator, putative pyruvate carboxylase regulator
K21742 ttdR; LysR family transcriptional regulator, transcriptional activator for ttdABT operon
K21755 bsdA; LysR family transcriptional regulator, salicylic acid-responsive activator of bsdBCD
K21756 catM; LysR family transcriptional regulator, cis,cis-muconate-responsive activator of cat and ben genes
K21757 benM; LysR family transcriptional regulator, benzoate and cis,cis-muconate-responsive activator of ben and cat genes
K21900 cysL; LysR family transcriptional regulator, transcriptional activator of the cysJI operon
K21959 ftsR; LysR family transcriptional regulator, cell division regulator
K22711 pltR; LysR family transcriptional regulator, pyoluteorin biosynthesis regulator
K23773 hdfR; LysR family transcriptional regulator, flagellar master operon regulator
K24082 pgrR; LysR family transcriptional regulator, regulator of peptidoglycan recycling
K26290 palR; LysR family transcriptional regulator, regulator of pal gene cluster
K27042 trpI; LysR family transcriptional regulator, trpBA operon transcriptional activator
K21960 ytlI; LysR family transcriptional regulator, regulator of the ytmI operon
K11534 deoR; DeoR family transcriptional regulator, deoxyribose operon repressor
K02444 glpR; DeoR family transcriptional regulator, glycerol-3-phosphate regulon repressor
K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor
K02436 gatR; DeoR family transcriptional regulator, galactitol utilization operon repressor
K02081 agaR; DeoR family transcriptional regulator, aga operon transcriptional repressor
K02430 fucR; DeoR family transcriptional regulator, L-fucose operon activator
K03436 fruR2, fruR; DeoR family transcriptional regulator, fructose operon transcriptional repressor
K02468 srlR, gutR; DeoR family transcriptional regulator, glucitol operon repressor
K03477 ulaR; DeoR family transcriptional regulator, ulaG and ulaABCDEF operon transcriptional repressor
K06283 spoIIID; putative DeoR family transcriptional regulator, stage III sporulation protein D
K06608 iolR; DeoR family transcriptional regulator, myo-inositol catabolism operon repressor
K20271 accR; DeoR family transcriptional regulator, repressor of opine catabolism and conjugal transfer
K22103 glcR; DeoR family transcriptional regulator, carbon catabolite repression regulator
K23774 ccpN; DeoR family transcriptional regulator, catabolite repression regulator
K27243 csqR; DeoR family transcriptional regulator, sulfoquinovose operon repressor
K21601 ycnK; DeoR family transcriptional regulator, copper-sensing transcriptional repressor
K09012 sufR; DeoR family transcriptional regulator, suf operon transcriptional repressor
K27069 lacI; LacI family transcriptional regulator, lactose operon repressor
K02529 galR; LacI family transcriptional regulator, galactose operon repressor
K02525 kdgR; LacI family transcriptional regulator, kdg operon repressor
K05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG
K03435 fruR1, fruR; LacI family transcriptional regulator, fructose operon transcriptional repressor
K03484 scrR; LacI family transcriptional regulator, sucrose operon repressor
K03485 treR; LacI family transcriptional regulator, trehalose operon repressor
K03487 ascG; LacI family transcriptional regulator, asc operon repressor
K03604 purR; LacI family transcriptional regulator, purine nucleotide synthesis repressor
K06145 gntR; LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor
K06146 idnR, gntH; LacI family transcriptional regulator, gluconate utilization system Gnt-II transcriptional activator
K12113 ebgR; LacI family transcriptional regulator, ebg operon repressor
K16136 malI; LacI family transcriptional regulator, maltose regulon regulatory protein
K17640 bxlR; LacI family transcriptional regulator, xylobiose transport system transcriptional regulator
K26609 exuR; LacI family transcriptional regulator, galacturonate utilization repressor
K02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor
K03482 yidP; GntR family transcriptional regulator, glv operon transcriptional regulator
K03486 treR2, treR; GntR family transcriptional regulator, trehalose operon transcriptional repressor
K03489 yydK; GntR family transcriptional regulator, transcriptional regulator of bglA
K03492 gmuR; GntR family transcriptional regulator, regulator of glucomannan utilization
K02043 phnF; GntR family transcriptional regulator, phosphonate transport system regulatory protein
K05836 hutC; GntR family transcriptional regulator, histidine utilization repressor
K10711 frlR; GntR family transcriptional regulator, frlABCD operon transcriptional regulator
K11922 mngR, farR; GntR family transcriptional regulator, mannosyl-D-glycerate transport/metabolism system repressor
K24966 gamR; GntR family transcriptional regulator, amino sugar utilization regulator
K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator
K24968 phnF; GntR family transcriptional regulator, repressor of the phnDCE operon
K24969 dasR; GntR family transcriptional regulator, nutrient-sensing system regulator
K03710 K03710; GntR family transcriptional regulator
K03603 fadR; GntR family transcriptional regulator, negative regulator for fad regulon and positive regulator of fabA
K05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex
K11474 glcC; GntR family transcriptional regulator, glc operon transcriptional activator
K13637 uxuR; GntR family transcriptional regulator, uxu operon transcriptional repressor
K19775 exuR; GntR family transcriptional regulator, hexuronate regulon transcriptional repressor
K14348 lldR; GntR family transcriptional regulator, L-lactate dehydrogenase operon regulator
K19776 dgoR; GntR family transcriptional regulator, galactonate operon transcriptional repressor
K22104 nanR; GntR family transcriptional regulator, sialic acid-inducible nan operon repressor
K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase
K18907 norG; GntR family transcriptional regulator, regulator for abcA and norABC
K07978 plmA; GntR family transcriptional regulator
K07979 ytrA; GntR family transcriptional regulator
K11476 gntR; GntR family transcriptional regulator, gluconate operon transcriptional repressor
K11475 vanR; GntR family transcriptional regulator, vanillate catabolism transcriptional regulator
K13654 mcbR; GntR family transcriptional regulator, colanic acid and biofilm gene transcriptional regulator
K15735 csiR; GntR family transcriptional regulator, carbon starvation induced regulator
K22293 rspR; GntR family transcriptional regulator, rspAB operon transcriptional repressor
K23015 lgoR; GntR family transcriptional regulator, transcriptional activator for L-galactonate catabolism
K23466 tgnR; GntR family transcriptional regulator, trigonelline degradation regulator
K18476 tetR; TetR/AcrR family transcriptional regulator, tetracycline repressor protein
K19047 tetC; TetR/AcrR family transcriptional regulator, repressor of tetCD
K02167 betI; TetR/AcrR family transcriptional regulator, transcriptional repressor of bet genes
K03577 acrR, smeT; TetR/AcrR family transcriptional regulator, acrAB operon repressor
K18136 acrR; TetR/AcrR family transcriptional regulator, multidrug resistance operon repressor
K05501 slmA, ttk; TetR/AcrR family transcriptional regulator
K09017 rutR; TetR/AcrR family transcriptional regulator
K10913 hapR, luxR, litR; TetR/AcrR family transcriptional regulator, hemagglutinin/protease regulatory protein
K19736 aefR; TetR/AcrR family transcriptional regulator, regulator of autoinduction and epiphytic fitness
K13770 ysiA, fadR; TetR/AcrR family transcriptional regulator, fatty acid metabolism regulator protein
K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
K16138 uidR; TetR/AcrR family transcriptional regulator, repressor for uid operon
K18301 mexL; TetR/AcrR family transcriptional regulator, mexJK operon transcriptional repressor
K18129 mexZ; TetR/AcrR family transcriptional regulator, mexXY operon repressor
K18130 nalC; TetR/AcrR family transcriptional regulator, transcriptional repressor NalC
K18135 nalD; TetR/AcrR family transcriptional regulator, repressor of the mexAB-oprM multidrug resistance operon
K18137 adeN; TetR/AcrR family transcriptional regulator, repressor of the adeIJK operon
K18140 envR, acrS; TetR/AcrR family transcriptional regulator, acrEF/envCD operon repressor
K18294 nfxB; TetR/AcrR family transcriptional regulator, mexCD-oprJ operon repressor
K18905 ameR, rmiR; TetR/AcrR family transcriptional regulator, repressor of the ameABC operon
K18937 lfrR; TetR/AcrR family transcriptional regulator, repressor for lfrA
K18938 qacR; TetR/AcrR family transcriptional regulator, repressor for qacA
K18939 lmrA, yxaF; TetR/AcrR family transcriptional regulator, lmrAB and yxaGH operons repressor
K18992 cmeR; TetR/AcrR family transcriptional regulator, cmeABC operon repressor
K19060 mphR; TetR/AcrR family transcriptional regulator, macrolide resistance operon repressor
K19335 bdcR; TetR/AcrR family transcriptional regulator, repressor for divergent bdcA
K20325 fhrR; TetR/AcrR family transcriptional regulator, Clp-modulated transcription factor
K21453 icaR; TetR/AcrR family transcriptional regulator, biofilm operon repressor
K21961 ethR, etaR; TetR/AcrR family transcriptional regulator, ethionamide resistance regulator
K21962 acnR; TetR/AcrR family transcriptional regulator, transcriptional repressor of aconitase
K22041 comR; TetR/AcrR family transcriptional regulator, copper-responsive repressor
K22105 fabR; TetR/AcrR family transcriptional regulator, fatty acid biosynthesis regulator
K22106 fatR, bscR; TetR/AcrR family transcriptional regulator, repressor of fatR-cypB operon
K22107 kstR; TetR/AcrR family transcriptional regulator, cholesterol catabolism regulator
K22108 kstR2; TetR/AcrR family transcriptional regulator, cholesterol catabolism regulator
K22294 nicS; TetR/AcrR family transcriptional regulator, upper aerobic nicotinate degradation pathway regulator
K23777 cecR; TetR/AcrR family transcriptional regulator, regulator of cefoperazone and chloramphenicol sensitivity
K24699 mftR; TetR/AcrR family transcriptional regulator, regulator of mycofactocin system
K27107 mce3R; TetR/AcrR family transcriptional regulator, mce3 operon repressor
K22295 K22295; TetR/AcrR family transcriptional regulator, repressor for neighboring sulfatase
K23778 rcdA; TetR/AcrR family transcriptional regulator, regulator of biofilm formation and stress response
K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
K06154 lysM; Lrp/AsnC family transcriptional regulator, involved in the regulation of lysine biosynthesis
K15782 doeX; Lrp/AsnC family transcriptional regulator, regulator of ectoine-degradation genes
K05800 decR, cyuR; Lrp/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator
K26601 azlB; Lrp/AsnC family transcriptional regulator, repressor for azl operon
K15852 luxR, vanR; LuxR family transcriptional regulator, transcriptional activator of the bioluminescence operon
K18304 lasR; LuxR family transcriptional regulator, quorum-sensing system regulator LasR
K18099 rhlR, phzR; LuxR family transcriptional regulator, quorum-sensing system regulator RhlR
K18098 bjaR1, rpaR, rhiR; LuxR family transcriptional regulator, quorum-sensing system regulator BjaR1
K07782 sdiA; LuxR family transcriptional regulator, quorum-sensing system regulator SdiA
K19666 solR, cepR, tofR; LuxR family transcriptional regulator, quorum-sensing system regulator SolR
K20540 cepR2; LuxR family transcriptional regulator, quorum-sensing system regulator CepR2
K19731 cciR; LuxR family transcriptional regulator, quorum-sensing system regulator CciR
K19732 traR; LuxR family transcriptional regulator, activator of conjugal transfer of Ti plasmids
K19733 sinR, avsR; LuxR family transcriptional regulator, quorum-sensing system regulator SinR
K19734 expR; LuxR family transcriptional regulator, quorum-sensing system regulator ExpR
K20252 cinR; LuxR family transcriptional regulator, quorum-sensing system regulator CinR
K20253 bisR; LuxR family transcriptional regulator, quorum-sensing system regulator BisR
K21697 vjbR; LuxR family transcriptional regulator, quorum-sensing system regulator VjbR
K21963 ecpR, matA; LuxR family transcriptional regulator, Mat/Ecp fimbriae transcriptional regulator
K25873 raiR; LuxR family transcriptional regulator, quorum-sensing system regulator RaiR
K07781 rcsA; LuxR family transcriptional regulator, capsular biosynthesis positive transcription factor
K04333 csgD; LuxR family transcriptional regulator, csgAB operon transcriptional regulatory protein
K01994 gerE; LuxR family transcriptional regulator, transcriptional regulator of spore coat protein
K20330 toxJ; LuxR family transcriptional regulator, activator of tox operons
K20334 cviR; LuxR family transcriptional regulator, quorum-sensing system regulator CviR
K20918 vpsT; LuxR family transcriptional regulator, positive regulator of biofilm formation
K21685 ramA; LuxR family transcriptional regulator, regulator of acetate metabolism
K21901 dctR; LuxR family transcriptional regulator, dicarboxylate transport regulator
K22650 bglJ; LuxR family transcriptional regulator, regulator of transport and utilization of aryl beta-glucosides
K24912 ramR, amfR; LuxR family transcriptional regulator, transcriptional activator for aerial hyphae formation
K03556 malT; LuxR family transcriptional regulator, maltose regulon positive regulatory protein
K21748 alkS; LuxR family transcriptional regulator, alkane degradation pathway regulator
K16247 gutR; LuxR family transcriptional regulator, glucitol operon activator
K21907 gadE; LuxR family transcriptional regulator, glutamate-dependent acid resistance regulator
K03712 marR; MarR family transcriptional regulator, multiple antibiotic resistance protein MarR
K06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin
K09682 hpr; MarR family transcriptional regulator, protease production regulatory protein HPr
K15973 mhqR; MarR family transcriptional regulator, 2-MHQ and catechol-resistance regulon repressor
K15974 emrR, mprA; MarR family transcriptional regulator, negative regulator of the multidrug operon emrRAB
K18131 mexR; MarR family transcriptional regulator, repressor of the mexAB-oprM multidrug resistance operon
K18906 mgrA; MarR family transcriptional regulator, multiple gene regulator MgrA
K18909 mepR; MarR family transcriptional regulator, repressor for mepA
K20338 rot; MarR family transcriptional regulator, global regulator for virulence
K21454 tcaR; MarR family transcriptional regulator, teicoplanin-associated locus regulator
K22296 nicR; MarR family transcriptional regulator, lower aerobic nicotinate degradation pathway regulator
K22489 hosA; MarR family transcriptional regulator, temperature-dependent positive regulator of motility
K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
K25883 expG, wggR; MarR family transcriptional regulator, exopolysaccharide II synthesis transcriptional activator
K03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor
K08365 merR; MerR family transcriptional regulator, mercuric resistance operon regulatory protein
K19057 merD; MerR family transcriptional regulator, mercuric resistance operon regulatory protein
K19591 cueR; MerR family transcriptional regulator, copper efflux regulator
K11923 cueR; MerR family transcriptional regulator, copper efflux regulator
K13638 zntR; MerR family transcriptional regulator, Zn(II)-responsive regulator of zntA
K13639 soxR; MerR family transcriptional regulator, redox-sensitive transcriptional activator SoxR
K13640 hspR; MerR family transcriptional regulator, heat shock protein HspR
K19575 bmrR; MerR family transcriptional regulator, activator of bmr gene
K19592 golS; MerR family transcriptional regulator, gold-responsive activator of gol and ges genes
K21089 mlrA; MerR family transcriptional regulator, activator of the csg genes
K21743 mta; MerR family transcriptional regulator, multidrug-efflux activator
K21744 tipA; MerR family transcriptional regulator, thiopeptide resistance regulator
K21745 adhR; MerR family transcriptional regulator, aldehyde-responsive regulator
K21972 bluR; MerR family transcriptional regulator, repressor of blue light- and temperature-responsive genes
K22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator
K23776 tnrA; MerR family transcriptional regulator, global nitrogen regulator
K21902 yfmP; MerR family transcriptional regulator, repressor of the yfmOP operon
K03711 fur, zur, furB; Fur family transcriptional regulator, ferric uptake regulator
K22297 furA; Fur family transcriptional regulator, stress-responsive regulator
K09823 zur; Fur family transcriptional regulator, zinc uptake regulator
K02076 zurR, zur; Fur family transcriptional regulator, zinc uptake regulator
K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator
K09826 irr; Fur family transcriptional regulator, iron response regulator
K13641 iclR; IclR family transcriptional regulator, acetate operon repressor
K02624 pcaR; IclR family transcriptional regulator, pca regulon regulatory protein
K05818 mhpR; IclR family transcriptional regulator, mhp operon transcriptional activator
K10973 allR; IclR family transcriptional regulator, negative regulator of allantoin and glyoxylate utilization operons
K19333 kdgR; IclR family transcriptional regulator, KDG regulon repressor
K20329 qsmR; IclR family transcriptional regulator, positive regulator for flagellar biogenesis
K20539 blcR; IclR family transcriptional regulator, blcABC operon repressor
K21602 yiaJ; IclR family transcriptional regulator, carbohydrate utilization repressor
K21827 arcR; IclR family transcriptional regulator, arginine deiminase pathway regulator
K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
K01420 fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein
K13642 ftrB; CRP/FNR family transcriptional regulator, transcriptional activator FtrB
K15861 fixK; CRP/FNR family transcriptional regulator, nitrogen fixation regulation protein
K21555 cooA; CRP/FNR family transcriptional regulator, carbon monoxide oxidation system transcription regulator
K21556 malR; CRP/FNR family transcriptional regulator, polysaccharide utilization system transcription regulator
K21558 cprK; CRP/FNR family transcriptional regulator, reductive dehalogenation system regulator
K21560 prfA; CRP/FNR family transcriptional regulator, listeriolysin regulatory protein
K21561 ntcA; CRP/FNR family transcriptional regulator, global nitrogen regulator
K21562 flp; CRP/FNR family transcriptional regulator, anaerobic regulatory protein
K21563 dnr; CRP/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator
K21564 nnrR; CRP/FNR family transcriptional regulator, nitrogen oxide reductase regulator
K21828 arcR; CRP/FNR family transcriptional regulator, arginine deiminase pathway regulator
K21884 cmr; CRP/FNR family transcriptional regulator, cAMP and macrophage regulator
K22490 ldrP; CRP/FNR family transcriptional regulator, LitR-dependent transcriptional activator
K16326 yeiL; CRP/FNR family transcriptional regulator, putaive post-exponential-phase nitrogen-starvation regulator
K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor
K13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor
K13772 rirA; Rrf2 family transcriptional regulator, iron-responsive regulator
K17472 cymR; Rrf2 family transcriptional regulator, cysteine metabolism repressor
K19587 oqxR; Rrf2 family transcriptional regulator, repressor of oqxAB
K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
K23988 arsR-arsC; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor / arsenate reductase (thioredoxin) [EC:1.20.4.4]
K21885 cmtR; ArsR family transcriptional regulator, cadmium/lead-responsive transcriptional repressor
K21886 nmtR; ArsR family transcriptional regulator, nickel/cobalt-responsive transcriptional repressor
K21903 cadC, smtB; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor
K22043 czrA; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor
K22298 smtB; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor
K22042 hlyU; ArsR family transcriptional regulator, virulence genes transcriptional regulator
K26993 sdpR; ArsR family transcriptional regulator, repressor of sdpIR and other operons
K07721 K07721; ArsR family transcriptional regulator
K15546 boxR, bzdR; XRE family transcriptional regulator, aerobic/anaerobic benzoate catabolism transcriptional regulator
K19449 sinR; XRE family transcriptional regulator, master regulator for biofilm formation
K21686 prpR; XRE family transcriptional regulator, fatty acid utilization regulator
K07110 ramB; XRE family transcriptional regulator, fatty acid utilization regulator
K22206 thiR; XRE family transcriptional regulator, thiamine biosynthesis regulator
K23779 sutR; XRE family transcriptional regulator, regulator of sulfur utilization
K19417 slrR; XRE family transcriptional regulator, biofilm formation regulator
K27043 clgR; XRE family transcriptional regulator, stress-response regulator
K26739 padR; PadR family transcriptional regulator, phenolic acid-responsive transcriptional regulator
K10917 aphA; PadR family transcriptional regulator, regulatory protein AphA
K26740 vanR; PadR family transcriptional regulator, regulator of vanillate utilization
K26741 ladR; PadR family transcriptional regulator, multidrug transcriptional repressor LadR
K26742 lmrR; PadR family transcriptional regulator, multidrug transcriptional repressor LmrR
K26743 pex; PadR family transcriptional regulator, circadian period extender
K23305 gvpE; PadR family transcriptional regulator, activator of gas vesicle formation
K10947 K10947; PadR family transcriptional regulator
K26252 dtxR, ideR; DtxR family transcriptional regulator, iron-dependent repressor
K03709 troR, sirR, scaR, mntR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
K11924 mntR; DtxR family transcriptional regulator, manganese transport regulator
K23238 rpiR, alsR; RpiR family transcriptional regulator, repressor of rpiB and als operon
K03481 glvR; RpiR family transcriptional regulator, glv operon transcriptional regulator
K15835 murR; RpiR family transcriptional regulator, murPQ operon repressor
K19337 hexR; RpiR family transcriptional regulator, carbohydrate utilization regulator
K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor
K02546 mecI; BlaI family transcriptional regulator, methicillin resistance regulatory protein
K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
K03720 trpR; TrpR family transcriptional regulator, trp operon repressor
K02688 prpR; transcriptional regulator, propionate catabolism operon regulatory protein
K07724 ner, nlp, sfsB; Ner family transcriptional regulator
K11925 sgrR; SgrR family transcriptional regulator
K06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22]
K13655 mqsA; HTH-type transcriptional regulator / antitoxin MqsA
K14056 puuR; HTH-type transcriptional regulator, repressor for puuD
K15773 hipB; HTH-type transcriptional regulator / antitoxin HipB
K18830 pezA; HTH-type transcriptional regulator / antitoxin PezA
K20480 nprR, nprA; HTH-type transcriptional regulator, quorum sensing regulator NprR
K20342 comR; HTH-type transcriptional regulator, regulator for ComX
K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator
K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor
K22299 rghR; HTH-type transcriptional regulator, competence development regulator
K22300 dicA; HTH-type transcriptional regulator, cell division transcriptional repressor
K20391 plcR; HTH-type transcriptional regulator, pleiotropic regulator of extracellular virulence genes
K20375 ropB, rgg1; HTH-type transcriptional regulator, pheromone-responsive regulator
K20380 traA; HTH-type transcriptional regulator, pheromone-responsive repressor
K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
K20388 cylR2; HTH-type transcriptional regulator, cytolysin regulator
K20377 prgX; HTH-type transcriptional regulator, major conjugation operon repressor
K21557 susR; HTH-type transcriptional regulator, polysaccharide utilization system transcription regulator
K09720 nrpRI; HTH-type transcriptional regulator, global nitrogen regulator NrpRI
K22109 gbsR; HTH-type transcriptional regulator, glycine betaine synthesis regulator
K22301 opcR; HTH-type transcriptional regulator, osmoprotectant uptake regulator
K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
K09714 tfx; HTH-type transcriptional regulator, fmd operon transcriptional regulator
K09685 purR; HTH-type transcriptional regulator, purine operon repressor
K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism
K10941 flrA, fleQ, flaK; sigma-54 dependent transcriptional regulator, flagellar regulatory protein
K18219 txr; sigma-54 dependent transcriptional regulator, tetracycline resistant transcriptional regulator
K20919 vpsR, cpsR; sigma-54 dependent transcriptional regulator, positive regulator of biofilm formation
K17473 dgaR; sigma-54 dependent transcriptional regulator, dga operon transcriptional activator
K19505 gfrR; sigma-54 dependent transcriptional regulator, gfr operon transcriptional activator
K21405 acoR; sigma-54 dependent transcriptional regulator, acetoin dehydrogenase operon transcriptional activator AcoR
K11908 vasH; sigma-54 dependent transcriptional regulator
K11917 sfa3; sigma-54 dependent transcriptional regulator
K11914 sfa2; sigma-54 dependent transcriptional regulator
K26990 rsoA; sigma-O factor regulatory protein RsoA
K12146 hyfR; hydrogenase-4 transcriptional activator
K12266 norR; anaerobic nitric oxide reductase transcription regulator
K15836 fhlA; formate hydrogenlyase transcriptional activator
K02584 nifA; Nif-specific regulatory protein
K02647 cdaR; carbohydrate diacid regulator
K06714 rocR; arginine utilization regulatory protein
K02019 modE; molybdate transport system regulatory protein
K01926 rex; redox-sensing transcriptional repressor
K03706 codY; transcriptional pleiotropic repressor
K17071 dcmR; transcriptional repressor of dcmA and dcmR
K07725 csa3; CRISPR-associated protein Csa3
K21829 dauR; D-arginine utilization repressor
K27097 espR; ESX-1-secreted protein regulator
K07726 K07726; putative transcriptional regulator
K07727 K07727; putative transcriptional regulator
K07728 K07728; putative transcriptional regulator
K07729 K07729; putative transcriptional regulator
K07730 K07730; putative transcriptional regulator
K07731 K07731; putative transcriptional regulator
K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
K07723 ndoAI; CopG family transcriptional regulator / antitoxin EndoAI
K03764 metJ; MetJ family transcriptional regulator, methionine regulon repressor
K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
K03488 licT, bglG; beta-glucoside operon transcriptional antiterminator
K26931 sacY; levansucrase and sucrase synthesis operon transcriptional antiterminator
K26932 sacT; sacPA operon transcriptional antiterminator
K03480 glcT; transcriptional antiterminator
K03493 bglG1; transcriptional antiterminator
K03483 mtlR; mannitol operon transcriptional activator
K02538 manR; mannose operon transcriptional activator
K03491 licR; probable licABCH operon transcriptional regulator
K18531 frvR; putative frv operon regulatory protein
K22976 atxA; anthrax toxin expression trans-acting positive regulator
K22977 acpA; capsule synthesis positive regulator AcpA
K22980 acpB; capsule synthesis positive regulator AcpB
K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
K18956 whiB5; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
K18957 whiB6; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
K18958 whiB7; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
K19339 nosR; NosR/NirI family transcriptional regulator, nitrous oxide reductase regulator
K19343 nirI; NosR/NirI family transcriptional regulator, nitrite reductase regulator
K21559 cprC; NosR/NirI family transcriptional regulator, putative reductive dehalogenation system regulator
K23239 frmR; FrmR/RcnR family transcriptional regulator, repressor of frmRAB operon
K23240 rcnR; FrmR/RcnR family transcriptional regulator, repressor of rcnA expression
K21600 csoR, ricR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor
K09684 pucR; PucR family transcriptional regulator, purine catabolism regulatory protein
K23253 putR; PucR family transcriptional regulator, proline-responsive transcriptional activator
K06284 abrB, abh; AbrB family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes
K04769 spoVT; AbrB family transcriptional regulator, stage V sporulation protein T
K21696 rcoM; LytTR family transcriptional regulator, CO-responsive transcriptional regulator RcoM
K05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator
K22894 embR; SARP family transcriptional regulator, regulator of embCAB operon
K03497 parB, spo0J; ParB family transcriptional regulator, chromosome partitioning protein
K23371 sbnI; L-serine kinase (ATP) / ParB family transcriptional regulator, heme-responsive regulator [EC:2.7.1.225]
K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription
K25884 mucR, rosR; MucR family transcriptional regulator, transcriptional regulator of exopolysaccharide biosynthesis
K02443 glpP; glycerol uptake operon antiterminator
K02531 lacT; transcriptional antiterminator
K05785 rfaH; transcriptional antiterminator RfaH
K03402 argR, ahrC; transcriptional regulator of arginine metabolism
K02565 nagC; N-acetylglucosamine repressor
K15545 mlc; transcriptional regulator of PTS gene
K02562 mtlR; mannitol operon repressor
K03705 hrcA; heat-inducible transcriptional repressor
K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
K10810 tenI; thiazole tautomerase (transcriptional regulator TenI) [EC:5.3.99.10]
K03708 ctsR; transcriptional regulator of stress and heat shock response
K03721 tyrR; transcriptional regulator of aroF, aroG, tyrA and aromatic amino acid transport
K03765 cadC; transcriptional activator of cad operon
K22486 hilA; transcriptional regulator HilA, main transcriptional regulator of SPI1
K03567 gcvR; glycine cleavage system transcriptional repressor
K02616 paaX; phenylacetic acid degradation operon negative regulatory protein
K03974 pspF; psp operon transcriptional activator
K03973 pspC; phage shock protein C
K05311 cggR; central glycolytic genes regulator
K05346 deoR; deoxyribonucleoside regulator
K11531 lsrR; lsr operon transcriptional repressor
K05519 med; transcriptional activator of comK gene
K05880 dhaR; transcriptional activator for dhaKLM operon
K06140 rnk; regulator of nucleoside diphosphate kinase
K06285 mtrB; transcription attenuation protein (tryptophan RNA-binding attenuator protein)
K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
K06314 rsfA; prespore-specific regulator
K06315 splA; transcriptional regulator of the spore photoproduct lyase operon
K07733 alpA; prophage regulatory protein
K07734 paiB; transcriptional regulator
K07735 algH; putative transcriptional regulator
K08277 caiF; transcriptional activator CaiF
K06204 dksA; RNA polymerase-binding transcription factor
K07738 nrdR; transcriptional repressor NrdR
K09683 hutP; hut operon positive regulatory protein
K11926 crl; sigma factor-binding protein Crl
K12296 comX1_2; competence protein ComX
K02250 comK; competence protein ComK
K14414 rtcR; transcriptional regulatory protein RtcR
K19667 xpsR; transcriptional activator of eps genes
K22302 dicC; transcriptional repressor of cell division inhibition gene dicB
K23306 brz; bacteriorhodopsin-regulating zinc finger protein
K03925 mraZ; transcriptional regulator MraZ
K08088 fimY; fimbrial regulator
K25885 exoR; exopolysaccharide production negative regulator
K07471 ygiV; probable transcriptional regulator
K26991 yvrL; membrane-bound negative regulator
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03021 Transcription machinery [BR:ko03021]
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03019 Messenger RNA biogenesis [BR:ko03019]
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03041 Spliceosome [BR:ko03041]
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03011 Ribosome [BR:ko03011]
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03009 Ribosome biogenesis [BR:ko03009]
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03016 Transfer RNA biogenesis [BR:ko03016]
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03012 Translation factors [BR:ko03012]
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03110 Chaperones and folding catalysts [BR:ko03110]
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04131 Membrane trafficking [BR:ko04131]
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04121 Ubiquitin system [BR:ko04121]
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03051 Proteasome [BR:ko03051]
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03032 DNA replication proteins [BR:ko03032]
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03036 Chromosome and associated proteins [BR:ko03036]
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03400 DNA repair and recombination proteins [BR:ko03400]
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03029 Mitochondrial biogenesis [BR:ko03029]
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09183 Protein families: signaling and cellular processes
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO)