KEGG Orthology (KO)

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 09100 Metabolism

 

 09120 Genetic Information Processing

 

 09130 Environmental Information Processing

 

   09131 Membrane transport

 

   09132 Signal transduction

     02020 Two-component system [PATH:ko02020]

     04010 MAPK signaling pathway [PATH:ko04010]

     04013 MAPK signaling pathway - fly [PATH:ko04013]

     04016 MAPK signaling pathway - plant [PATH:ko04016]

     04011 MAPK signaling pathway - yeast [PATH:ko04011]

     04012 ErbB signaling pathway [PATH:ko04012]

     04014 Ras signaling pathway [PATH:ko04014]

     04015 Rap1 signaling pathway [PATH:ko04015]

     04310 Wnt signaling pathway [PATH:ko04310]

     04330 Notch signaling pathway [PATH:ko04330]

     04340 Hedgehog signaling pathway [PATH:ko04340]

     04341 Hedgehog signaling pathway - fly [PATH:ko04341]

     04350 TGF-beta signaling pathway [PATH:ko04350]

     04390 Hippo signaling pathway [PATH:ko04390]

     04391 Hippo signaling pathway - fly [PATH:ko04391]

     04392 Hippo signaling pathway - multiple species [PATH:ko04392]

     04370 VEGF signaling pathway [PATH:ko04370]

     04371 Apelin signaling pathway [PATH:ko04371]

     04630 JAK-STAT signaling pathway [PATH:ko04630]

       K05429  IL2; interleukin 2
       K05430  IL4; interleukin 4
       K05431  IL7; interleukin 7
       K05432  IL9; interleukin 9
       K05433  IL15; interleukin 15
       K05434  IL21; interleukin 21
       K05436  TSLP; thymic stromal lymphopoietin
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05069  IL2RB, CD122; interleukin 2 receptor beta
       K05070  IL2RG, CD132; interleukin 2 receptor gamma
       K05071  IL4R, CD124; interleukin 4 receptor
       K05072  IL7R, CD127; interleukin 7 receptor
       K05073  IL9R, CD129; interleukin 9 receptor
       K05074  IL15RA, CD215; interleukin 15 receptor alpha
       K05075  IL21R, CD360; interleukin 21 receptor
       K05078  TSLPR; thymic stromal-derived lymphopoietin receptor
       K04736  IL3; interleukin 3
       K05428  IL5; interleukin 5
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K04737  IL3RA, CD123; interleukin 3 receptor alpha
       K05067  IL5RA, CD125; interleukin 5 receptor alpha
       K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
       K04738  CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
       K05405  IL6; interleukin 6
       K05417  IL11; interleukin 11
       K05435  IL13; interleukin 13
       K22629  IL27, IL27A; interleukin 27 subunit alpha
       K22631  IL31; interleukin 31
       K05418  OSM; oncostatin M
       K05419  LIF; leukemia inhibitory factor
       K05420  CNTF; ciliary neurotrophic factor
       K05422  CTF1, CT1; cardiotrophin 1
       K24382  CTF2; cardiotrophin 2
       K05421  CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
       K05055  IL6R, CD126; interleukin 6 receptor
       K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
       K05056  IL11RA; interleukin 11 receptor alpha
       K05076  IL13RA1, CD213A1; interleukin 13 receptor alpha-1
       K05077  IL13RA2, CD213A2; interleukin 13 receptor alpha-2
       K19598  IL27RA; interleukin 27 receptor alpha
       K22630  IL31RA; interleukin 31 receptor subunit alpha
       K05057  OSMR; oncostatin M receptor
       K05058  LIFR, CD118; leukemia inhibitory factor receptor
       K05059  CNTFR; ciliary neurotrophic factor receptor
       K05443  IL10, CSIF; interleukin 10
       K05444  IL19; interleukin 19
       K05445  IL22, IL-TIF; interleukin 22
       K22667  IL20; interleukin 20
       K22668  IL24; interleukin 24
       K05446  IL26; interleukin 26
       K05134  IL10RA, CD210A; interleukin 10 receptor alpha
       K05135  IL10RB, CD210B; interleukin 10 receptor beta
       K05136  IL20RA; interleukin 20 receptor alpha
       K05137  IL20RB; interleukin 20 receptor beta
       K05138  IL22RA1; interleukin 22 receptor alpha 1
       K05139  IL22RA2; interleukin 22 receptor alpha 2
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K05426  IL23A; interleukin 23 subunit alpha
       K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
       K05064  IL12RB2; interleukin 12 receptor beta-2
       K05065  IL23R; interleukin 23 receptor
       K05437  EPO; erythropoietin
       K05438  GH; growth hormone
       K05439  PRL; prolactin
       K06854  THPO; thrombopoietin
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05424  LEP; leptin
       K16689  UPD; unpaired
       K05079  EPOR; erythropoietin receptor
       K05080  GHR; growth hormone receptor
       K05081  PRLR; prolactin receptor
       K05082  TPOR, MPL, CD110; thrombopoietin receptor
       K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
       K05062  LEPR, CD295; leptin receptor
       K19599  DOME; cytokine receptor domeless
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05442  IFNE; interferon epsilon
       K05441  IFNK; interferon kappa
       K05447  IFNL1, IL29; interferon lambda 1
       K22669  IFNL2_3, IL28; interferon lambda 2/3
       K05440  IFNW; interferon omega
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05140  IFNLR1, IL28RA; interferon lambda receptor 1
       K04687  IFNG; interferon gamma
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K04357  EGF; epidermal growth factor
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K04692  STAT3; signal transducer and activator of transcription 3
       K11222  STAT4; signal transducer and activator of transcription 4
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K11225  STAT6; signal transducer and activator of transcription 6
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K04701  CISH; cytokine inducible SH2-containing protein
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K04697  SOCS4; suppressor of cytokine signaling 4
       K04698  SOCS5; suppressor of cytokine signaling 5
       K04699  SOCS6_7; suppressor of cytokine signaling 6/7
       K02161  BCL2; apoptosis regulator Bcl-2
       K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K04702  PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; G1/S-specific cyclin-D1
       K10151  CCND2; G1/S-specific cyclin-D2
       K10152  CCND3; G1/S-specific cyclin-D3
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K00157  AOX; aldehyde oxidase [EC:1.2.3.1]
       K05640  GFAP; glial fibrillary acidic protein
       K04705  STAM; signal transducing adaptor molecule
       K18026  PTPN2, PTPT; tyrosine-protein phosphatase non-receptor type 2 [EC:3.1.3.48]
       K05697  PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K04706  PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
       K16063  PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
       K16064  PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
       K16065  PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
       K14365  FHL1, SLIM1; four and a half LIM domains protein 1
       K07293  PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K04364  GRB2; growth factor receptor-bound protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]

     04064 NF-kappa B signaling pathway [PATH:ko04064]

     04668 TNF signaling pathway [PATH:ko04668]

     04066 HIF-1 signaling pathway [PATH:ko04066]

     04068 FoxO signaling pathway [PATH:ko04068]

     04020 Calcium signaling pathway [PATH:ko04020]

     04070 Phosphatidylinositol signaling system [PATH:ko04070]

     04072 Phospholipase D signaling pathway [PATH:ko04072]

     04071 Sphingolipid signaling pathway [PATH:ko04071]

     04024 cAMP signaling pathway [PATH:ko04024]

     04022 cGMP-PKG signaling pathway [PATH:ko04022]

     04151 PI3K-Akt signaling pathway [PATH:ko04151]

     04152 AMPK signaling pathway [PATH:ko04152]

     04150 mTOR signaling pathway [PATH:ko04150]

     04075 Plant hormone signal transduction [PATH:ko04075]

 

   09133 Signaling molecules and interaction

     04080 Neuroactive ligand-receptor interaction [PATH:ko04080]

     04060 Cytokine-cytokine receptor interaction [PATH:ko04060]

       K05514  CCL1; C-C motif chemokine 1
       K13072  CCL25; C-C motif chemokine 25
       K05512  CCL19, ELC; C-C motif chemokine 19
       K16062  CCL21, SLC; C-C motif chemokine 21
       K05408  CCL3; C-C motif chemokine 3
       K12964  CCL4; C-C motif chemokine 4
       K21083  CCL17; C-C motif chemokine 17
       K21095  CCL22; C-C motif chemokine 22
       K12499  CCL5; C-C motif chemokine 5
       K16596  CCL8; C-C motif chemokine 8
       K22671  CCL9; C-C motif chemokine 9
       K21092  CCL14; C-C motif chemokine 14
       K21093  CCL16; C-C motif chemokine 16
       K05511  CCL15_23; C-C motif chemokine 15/23
       K16595  CCL13; C-C motif chemokine 13
       K05510  CCL6; C-C motif chemokine 6
       K05509  CCL7; C-C motif chemokine 7
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K16597  CCL11; C-C motif chemokine 11
       K21097  CCL24; C-C motif chemokine 24
       K21096  CCL26; C-C motif chemokine 26
       K16598  CCL27; C-C motif chemokine 27
       K05513  CCL28; C-C motif chemokine 28
       K21094  CCL18; C-C motif chemokine 18
       K14625  CCL20; C-C motif chemokine 20
       K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
       K05506  CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
       K10030  IL8, CXCL8; interleukin 8
       K10029  PPBP, CXCL7; platelet basic protein
       K05407  PF4, CXCL4; platelet factor 4
       K05416  CXCL9; C-X-C motif chemokine 9
       K12671  CXCL10, IP10; C-X-C motif chemokine 10
       K12672  CXCL11, I-TAC; C-X-C motif chemokine 11
       K10032  CXCL13; C-X-C motif chemokine 13
       K10031  CXCL12; C-X-C motif chemokine 12
       K10035  CXCL16; C-X-C motif chemokine 16
       K10033  CXCL14, SCYB14; C-X-C motif chemokine 14
       K10034  CXCL15; C-X-C motif chemokine 15
       K22627  CXCL17; C-X-C motif chemokine 17
       K05507  XCL1, SCM1; C motif chemokine 1
       K22675  XCL2, SCM1B; C motif chemokine 2
       K05508  CX3CL1, NTT; C-X3-C motif chemokine 1
       K05429  IL2; interleukin 2
       K05430  IL4; interleukin 4
       K05431  IL7; interleukin 7
       K05432  IL9; interleukin 9
       K05433  IL15; interleukin 15
       K05434  IL21; interleukin 21
       K05436  TSLP; thymic stromal lymphopoietin
       K04736  IL3; interleukin 3
       K05428  IL5; interleukin 5
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K05435  IL13; interleukin 13
       K05437  EPO; erythropoietin
       K05438  GH; growth hormone
       K05439  PRL; prolactin
       K06854  THPO; thrombopoietin
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05424  LEP; leptin
       K05405  IL6; interleukin 6
       K05417  IL11; interleukin 11
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K05426  IL23A; interleukin 23 subunit alpha
       K22629  IL27, IL27A; interleukin 27 subunit alpha
       K24476  EBI3, IL27B; interleukin 27 subunit beta
       K22631  IL31; interleukin 31
       K05421  CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
       K05420  CNTF; ciliary neurotrophic factor
       K05422  CTF1, CT1; cardiotrophin 1
       K24382  CTF2; cardiotrophin 2
       K05419  LIF; leukemia inhibitory factor
       K05418  OSM; oncostatin M
       K05443  IL10, CSIF; interleukin 10
       K05444  IL19; interleukin 19
       K22667  IL20; interleukin 20
       K22668  IL24; interleukin 24
       K05445  IL22, IL-TIF; interleukin 22
       K05446  IL26; interleukin 26
       K22669  IFNL2_3, IL28; interferon lambda 2/3
       K05447  IFNL1, IL29; interferon lambda 1
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05440  IFNW; interferon omega
       K05441  IFNK; interferon kappa
       K05442  IFNE; interferon epsilon
       K04687  IFNG; interferon gamma
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K05481  IL1RN, IL1F3; interleukin 1 receptor antagonist
       K05483  IL36RN, IL1F5; interleukin 36 receptor antagonist protein
       K05484  IL36A, IL1F6; interleukin 36 alpha
       K05486  IL36B, IL1F8; interleukin 36 beta
       K05487  IL36G, IL1F9; interleukin 36 gamma
       K05488  IL1F10, FKSG75; interleukin 1 family member 10
       K05485  IL37, IL1F7; interleukin 37
       K05482  IL18, IL1F4; interleukin 18
       K12967  IL33; interleukin 33
       K05489  IL17A, CTLA8; interleukin 17A
       K05494  IL17F, ML1; interleukin 17F
       K05490  IL17B, CX1; interleukin 17B
       K05491  IL17C, CX2; interleukin 17C
       K05492  IL17D, IL27; interleukin 17D
       K05493  IL17E, IL25; interleukin 17E
       K22628  IL16; interleukin 16
       K22632  IL32; interleukin 32
       K22633  IL34; interleukin 34
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
       K03157  LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
       K05477  TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K05478  TNFSF15, VEGI; tumor necrosis factor ligand superfamily member 15
       K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
       K05480  EDA; ectodysplasin-A
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
       K05474  TNFSF12, TWEAK; tumor necrosis factor ligand superfamily member 12
       K05470  TNFSF7, CD70; tumor necrosis factor ligand superfamily member 7
       K05471  TNFSF8, CD153; tumor necrosis factor ligand superfamily member 8
       K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
       K05472  TNFSF9, CD137L; tumor necrosis factor ligand superfamily member 9
       K05469  TNFSF4, OX40L, CD252; tumor necrosis factor ligand superfamily member 4
       K05479  TNFSF18, GITRL; tumor necrosis factor ligand superfamily member 18
       K05475  TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
       K05476  TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K05504  GDF15; growth differentiation factor 15
       K05503  GDF2, BMP9; growth differentiation factor 2
       K22670  BMP10; bone morphogenetic protein 10
       K05500  INHA; inhibin, alpha
       K05496  BMP3; bone morphogenetic protein 3
       K22674  GDF10, BMP3B; growth differentiation factor 10
       K22679  GDF11; growth differentiation factor 11
       K05497  MSTN, GDF8; growth differentiation factor 8
       K04667  INHBA; inhibin beta A chain
       K22687  INHBB; inhibin beta B chain
       K05495  GDF1; growth differentiation factor 1
       K22672  GDF3; growth differentiation factor 3
       K04666  NODAL; nodal
       K22673  GDF9; growth differentiation factor 9
       K22688  INHBC; inhibin beta C chain
       K22689  INHBE; inhibin beta E chain
       K04665  AMH; anti-mullerian hormone
       K21283  BMP2; bone morphogenetic protein 2
       K04662  BMP4; bone morphogenetic protein 4
       K04664  GDF5; growth differentiation factor 5
       K20012  GDF6; growth differentiation factor 6
       K20013  GDF7; growth differentiation factor 7
       K05498  BMP15, GDF9B; bone morphogenetic protein 15
       K04663  BMP5; bone morphogenetic protein 5
       K16620  BMP6; bone morphogenetic protein 6
       K16621  BMP7; bone morphogenetic protein 7
       K16622  BMP8; bone morphogenetic protein 8
       K04183  CCR8, CDw198; C-C chemokine receptor type 8
       K04184  CCR9, CDw199; C-C chemokine receptor type 9
       K04186  ACKR4, CCRL1, CCR11; atypical chemokine receptor 4
       K04182  CCR7, CD197; C-C chemokine receptor type 7
       K04179  CCR4, CD194; C-C chemokine receptor type 4
       K04180  CCR5, CD195; C-C chemokine receptor type 5
       K04178  CCR3, CD193; C-C chemokine receptor type 3
       K04177  CCR2, CD192; C-C chemokine receptor type 2
       K04176  CCR1, CD191; C-C chemokine receptor type 1
       K04185  CCR10; C-C chemokine receptor type 10
       K04181  CCR6, CD196; C-C chemokine receptor type 6
       K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
       K05050  CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
       K04188  CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
       K04190  CXCR5, BLR1, CD185; C-X-C chemokine receptor type 5
       K04189  CXCR4, CD184; C-X-C chemokine receptor type 4
       K04304  CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
       K04191  CXCR6, CD186; C-X-C chemokine receptor type 6
       K04193  XCR1; XC chemokine receptor 1
       K04192  CX3CR1; CX3C chemokine receptor 1
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05069  IL2RB, CD122; interleukin 2 receptor beta
       K05070  IL2RG, CD132; interleukin 2 receptor gamma
       K05071  IL4R, CD124; interleukin 4 receptor
       K05072  IL7R, CD127; interleukin 7 receptor
       K05073  IL9R, CD129; interleukin 9 receptor
       K05074  IL15RA, CD215; interleukin 15 receptor alpha
       K05075  IL21R, CD360; interleukin 21 receptor
       K05078  TSLPR; thymic stromal-derived lymphopoietin receptor
       K04737  IL3RA, CD123; interleukin 3 receptor alpha
       K04738  CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
       K05067  IL5RA, CD125; interleukin 5 receptor alpha
       K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
       K05076  IL13RA1, CD213A1; interleukin 13 receptor alpha-1
       K05077  IL13RA2, CD213A2; interleukin 13 receptor alpha-2
       K05079  EPOR; erythropoietin receptor
       K05080  GHR; growth hormone receptor
       K05081  PRLR; prolactin receptor
       K05082  TPOR, MPL, CD110; thrombopoietin receptor
       K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
       K05062  LEPR, CD295; leptin receptor
       K05055  IL6R, CD126; interleukin 6 receptor
       K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
       K05056  IL11RA; interleukin 11 receptor alpha
       K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
       K05064  IL12RB2; interleukin 12 receptor beta-2
       K05065  IL23R; interleukin 23 receptor
       K19598  IL27RA; interleukin 27 receptor alpha
       K22630  IL31RA; interleukin 31 receptor subunit alpha
       K05059  CNTFR; ciliary neurotrophic factor receptor
       K05058  LIFR, CD118; leukemia inhibitory factor receptor
       K05057  OSMR; oncostatin M receptor
       K05134  IL10RA, CD210A; interleukin 10 receptor alpha
       K05135  IL10RB, CD210B; interleukin 10 receptor beta
       K05136  IL20RA; interleukin 20 receptor alpha
       K05137  IL20RB; interleukin 20 receptor beta
       K05138  IL22RA1; interleukin 22 receptor alpha 1
       K05140  IFNLR1, IL28RA; interferon lambda receptor 1
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K04386  IL1R1, CD121a; interleukin 1 receptor type I
       K04723  IL1RAP; interleukin 1 receptor accessory protein
       K04387  IL1R2, CD121b; interleukin 1 receptor type II
       K05172  IL1RL2, IL1RRP2; interleukin 1 receptor-like 2
       K05173  IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
       K05174  IL18RAP, ACPL, CD218b; interleukin 18 receptor accessory protein
       K05171  IL1RL1, ST2; interleukin 1 receptor-like 1
       K05164  IL17RA, CD217; interleukin 17 receptor A
       K05166  IL17RC, IL17RL; interleukin 17 receptor C
       K05165  IL17RB, IL17RH1; interleukin 17 receptor B
       K05168  IL17RE; interleukin 17 receptor E
       K06454  CD4; T-cell surface glycoprotein CD4
       K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K05141  TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K05152  TNFRSF14, HVEM, CD270; tumor necrosis factor receptor superfamily member 14
       K05143  TNFRSF6B, DCR3; tumor necrosis factor receptor superfamily member 6B
       K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
       K05160  TNFRSF25; tumor necrosis factor receptor superfamily member 25
       K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
       K22701  TNFRSF10C, TRAILR3, DCR1, CD263; tumor necrosis factor receptor superfamily member 10C
       K22702  TNFRSF10D, TRAILR4, DCR2, CD264; tumor necrosis factor receptor superfamily member 10D
       K05157  TNFRSF21, DR6, CD358; tumor necrosis factor receptor superfamily member 21
       K05162  EDAR; tumor necrosis factor receptor superfamily member EDAR
       K05163  EDA2R, TNFRSF27, XEDAR; tumor necrosis factor receptor superfamily member 27
       K02583  NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
       K05148  TNFRSF11B, OPG; tumor necrosis factor receptor superfamily member 11B
       K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
       K05149  TNFRSF12A, FN14, TWEAKR, CD266; tumor necrosis factor receptor superfamily member 12A
       K05144  TNFRSF7, CD27; tumor necrosis factor receptor superfamily member 7
       K05145  TNFRSF8, CD30; tumor necrosis factor receptor superfamily member 8
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K05146  TNFRSF9, CD137; tumor necrosis factor receptor superfamily member 9
       K05142  TNFRSF4, OX40, CD134; tumor necrosis factor receptor superfamily member 4
       K05154  TNFRSF18, GITR, CD357; tumor necrosis factor receptor superfamily member 18
       K05153  TNFRSF17, BCMA, CD269; tumor necrosis factor receptor superfamily member 17
       K05150  TNFRSF13B, TACI, CD267; tumor necrosis factor receptor superfamily member 13B
       K05151  TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
       K05155  TNFRSF19, TROY; tumor necrosis factor receptor superfamily member 19
       K05156  RELT, TNFRSF19L; tumor necrosis factor receptor superfamily member 19-like
       K26541  RELL; RELT-like protein
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K13594  ACVRL1, ALK1; activin receptor-like kinase 1 [EC:2.7.11.30]
       K04670  ACVR2A; activin receptor type-2A [EC:2.7.11.30]
       K04671  BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
       K13596  ACVR2B; activin receptor type-2B [EC:2.7.11.30]
       K13567  ACVR1B, ALK4; activin receptor type-1B [EC:2.7.11.30]
       K13568  ACVR1C, ALK7; activin receptor type-1C [EC:2.7.11.30]
       K04675  ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
       K04672  AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]
       K04673  BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
       K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]

     04061 Viral protein interaction with cytokine and cytokine receptor [PATH:ko04061]

     04512 ECM-receptor interaction [PATH:ko04512]

     04514 Cell adhesion molecules [PATH:ko04514]

 

 09140 Cellular Processes

 

 09150 Organismal Systems

 

 09160 Human Diseases

 

 09180 Brite Hierarchies

 

   09181 Protein families: metabolism

 

   09182 Protein families: genetic information processing

 

   09183 Protein families: signaling and cellular processes

     02000 Transporters [BR:ko02000]

     02044 Secretion system [BR:ko02044]

     02042 Bacterial toxins [BR:ko02042]

     02022 Two-component system [BR:ko02022]

     02035 Bacterial motility proteins [BR:ko02035]

     03037 Cilium and associated proteins [BR:ko03037]

     04812 Cytoskeleton proteins [BR:ko04812]

     04147 Exosome [BR:ko04147]

     02048 Prokaryotic defense system [BR:ko02048]

     04030 G protein-coupled receptors [BR:ko04030]

     04050 Cytokine receptors [BR:ko04050]

     04054 Pattern recognition receptors [BR:ko04054]

     03310 Nuclear receptors [BR:ko03310]

     04040 Ion channels [BR:ko04040]

     04031 GTP-binding proteins [BR:ko04031]

     04052 Cytokines and neuropeptides [BR:ko04052]

       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K05481  IL1RN, IL1F3; interleukin 1 receptor antagonist
       K05488  IL1F10, FKSG75; interleukin 1 family member 10
       K05429  IL2; interleukin 2
       K04736  IL3; interleukin 3
       K05430  IL4; interleukin 4
       K05428  IL5; interleukin 5
       K05405  IL6; interleukin 6
       K05431  IL7; interleukin 7
       K05432  IL9; interleukin 9
       K05443  IL10, CSIF; interleukin 10
       K05417  IL11; interleukin 11
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K05435  IL13; interleukin 13
       K05433  IL15; interleukin 15
       K22628  IL16; interleukin 16
       K05489  IL17A, CTLA8; interleukin 17A
       K05490  IL17B, CX1; interleukin 17B
       K05491  IL17C, CX2; interleukin 17C
       K05492  IL17D, IL27; interleukin 17D
       K05493  IL17E, IL25; interleukin 17E
       K05494  IL17F, ML1; interleukin 17F
       K05482  IL18, IL1F4; interleukin 18
       K05444  IL19; interleukin 19
       K22667  IL20; interleukin 20
       K05434  IL21; interleukin 21
       K05445  IL22, IL-TIF; interleukin 22
       K05426  IL23A; interleukin 23 subunit alpha
       K22668  IL24; interleukin 24
       K05446  IL26; interleukin 26
       K22629  IL27, IL27A; interleukin 27 subunit alpha
       K24476  EBI3, IL27B; interleukin 27 subunit beta
       K22631  IL31; interleukin 31
       K22632  IL32; interleukin 32
       K12967  IL33; interleukin 33
       K22633  IL34; interleukin 34
       K05484  IL36A, IL1F6; interleukin 36 alpha
       K05486  IL36B, IL1F8; interleukin 36 beta
       K05487  IL36G, IL1F9; interleukin 36 gamma
       K05483  IL36RN, IL1F5; interleukin 36 receptor antagonist protein
       K05485  IL37, IL1F7; interleukin 37
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K04687  IFNG; interferon gamma
       K05442  IFNE; interferon epsilon
       K05441  IFNK; interferon kappa
       K05447  IFNL1, IL29; interferon lambda 1
       K22669  IFNL2_3, IL28; interferon lambda 2/3
       K05440  IFNW; interferon omega
       K27353  IFNT; interferon tau
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05437  EPO; erythropoietin
       K05438  GH; growth hormone
       K06854  THPO; thrombopoietin
       K05436  TSLP; thymic stromal lymphopoietin
       K05418  OSM; oncostatin M
       K05419  LIF; leukemia inhibitory factor
       K05420  CNTF; ciliary neurotrophic factor
       K05421  CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
       K05422  CTF1, CT1; cardiotrophin 1
       K24382  CTF2; cardiotrophin 2
       K05514  CCL1; C-C motif chemokine 1
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K05408  CCL3; C-C motif chemokine 3
       K12964  CCL4; C-C motif chemokine 4
       K12499  CCL5; C-C motif chemokine 5
       K05510  CCL6; C-C motif chemokine 6
       K05509  CCL7; C-C motif chemokine 7
       K16596  CCL8; C-C motif chemokine 8
       K22671  CCL9; C-C motif chemokine 9
       K16597  CCL11; C-C motif chemokine 11
       K16595  CCL13; C-C motif chemokine 13
       K21092  CCL14; C-C motif chemokine 14
       K05511  CCL15_23; C-C motif chemokine 15/23
       K21093  CCL16; C-C motif chemokine 16
       K21083  CCL17; C-C motif chemokine 17
       K21094  CCL18; C-C motif chemokine 18
       K05512  CCL19, ELC; C-C motif chemokine 19
       K14625  CCL20; C-C motif chemokine 20
       K16062  CCL21, SLC; C-C motif chemokine 21
       K21095  CCL22; C-C motif chemokine 22
       K21097  CCL24; C-C motif chemokine 24
       K13072  CCL25; C-C motif chemokine 25
       K21096  CCL26; C-C motif chemokine 26
       K16598  CCL27; C-C motif chemokine 27
       K05513  CCL28; C-C motif chemokine 28
       K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
       K05407  PF4, CXCL4; platelet factor 4
       K05506  CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
       K10029  PPBP, CXCL7; platelet basic protein
       K10030  IL8, CXCL8; interleukin 8
       K05416  CXCL9; C-X-C motif chemokine 9
       K12671  CXCL10, IP10; C-X-C motif chemokine 10
       K12672  CXCL11, I-TAC; C-X-C motif chemokine 11
       K10031  CXCL12; C-X-C motif chemokine 12
       K10032  CXCL13; C-X-C motif chemokine 13
       K10033  CXCL14, SCYB14; C-X-C motif chemokine 14
       K10034  CXCL15; C-X-C motif chemokine 15
       K10035  CXCL16; C-X-C motif chemokine 16
       K22627  CXCL17; C-X-C motif chemokine 17
       K05508  CX3CL1, NTT; C-X3-C motif chemokine 1
       K05507  XCL1, SCM1; C motif chemokine 1
       K22675  XCL2, SCM1B; C motif chemokine 2
       K24191  PROK; prokineticin
       K25387  GPR15L; protein GPR15L
       K25418  CYTL1; cytokine-like protein 1
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
       K03157  LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
       K05469  TNFSF4, OX40L, CD252; tumor necrosis factor ligand superfamily member 4
       K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K05470  TNFSF7, CD70; tumor necrosis factor ligand superfamily member 7
       K05471  TNFSF8, CD153; tumor necrosis factor ligand superfamily member 8
       K05472  TNFSF9, CD137L; tumor necrosis factor ligand superfamily member 9
       K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
       K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
       K05474  TNFSF12, TWEAK; tumor necrosis factor ligand superfamily member 12
       K05475  TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
       K05476  TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
       K05477  TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
       K05478  TNFSF15, VEGI; tumor necrosis factor ligand superfamily member 15
       K05479  TNFSF18, GITRL; tumor necrosis factor ligand superfamily member 18
       K05480  EDA; ectodysplasin-A
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04384  TGFBN; transforming growth factor beta, invertebrate
       K05502  BMP1, TLD; bone morphogenetic protein 1 [EC:3.4.24.19]
       K21283  BMP2; bone morphogenetic protein 2
       K05496  BMP3; bone morphogenetic protein 3
       K04662  BMP4; bone morphogenetic protein 4
       K04663  BMP5; bone morphogenetic protein 5
       K16620  BMP6; bone morphogenetic protein 6
       K16621  BMP7; bone morphogenetic protein 7
       K16622  BMP8; bone morphogenetic protein 8
       K22670  BMP10; bone morphogenetic protein 10
       K05498  BMP15, GDF9B; bone morphogenetic protein 15
       K05495  GDF1; growth differentiation factor 1
       K05503  GDF2, BMP9; growth differentiation factor 2
       K22672  GDF3; growth differentiation factor 3
       K04664  GDF5; growth differentiation factor 5
       K20012  GDF6; growth differentiation factor 6
       K20013  GDF7; growth differentiation factor 7
       K05497  MSTN, GDF8; growth differentiation factor 8
       K22673  GDF9; growth differentiation factor 9
       K22674  GDF10, BMP3B; growth differentiation factor 10
       K22679  GDF11; growth differentiation factor 11
       K05504  GDF15; growth differentiation factor 15
       K04666  NODAL; nodal
       K05500  INHA; inhibin, alpha
       K04667  INHBA; inhibin beta A chain
       K22687  INHBB; inhibin beta B chain
       K22688  INHBC; inhibin beta C chain
       K22689  INHBE; inhibin beta E chain
       K04665  AMH; anti-mullerian hormone
       K04668  LEFTY; left-right determination factor
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K16859  PGF; placenta growth factor
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04356  NTF3; neurotrophin 3
       K12457  NTF4; neurotrophin 4
       K04355  BDNF; brain-derived neurotrophic factor
       K05452  GDNF; glial cell derived neurotrophic factor
       K25414  NRTN; neurturin
       K25415  ARTN; artemin
       K25416  PSPN; persephin
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K18496  FGF1; fibroblast growth factor 1
       K18497  FGF2; fibroblast growth factor 2
       K04358  FGF; fibroblast growth factor
       K22413  FGF11_12_13, FHF3_1_2; fibroblast growth factor 11/12/13
       K23920  FGF14, FHF4; fibroblast growth factor 14
       K22603  FGF19; fibroblast growth factor 19
       K22429  FGF21; fibroblast growth factor 21
       K22428  FGF23; fibroblast growth factor 23
       K05455  NRG1; neuregulin 1
       K05456  NRG2; neuregulin 2
       K05457  NRG3; neuregulin 3
       K05458  NRG4; neuregulin 4
       K05459  IGF1; insulin-like growth factor 1
       K13769  IGF2; insulin-like growth factor 2
       K05460  HGF; hepatocyte growth factor
       K04357  EGF; epidermal growth factor
       K08774  TGFA; transforming growth factor, alpha
       K09784  EREG; epiregulin
       K09782  AREG; amphiregulin
       K05461  KITLG; KIT ligand
       K05462  EFNA; ephrin-A
       K05463  EFNB; ephrin-B
       K05464  GAS6; growth arrest-specific 6
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K09821  AGT, SERPINA8; angiotensinogen
       K03898  KNG, BK; kininogen
       K05235  NTS; neurotensin
       K05225  APLN; apelin
       K05223  NMB; neuromedin B
       K05224  GRP; gastrin-releasing peptide
       K05226  CCK; cholecystokinin
       K16366  EDN1; endothelin-1
       K16367  EDN2; endothelin-2
       K05227  EDN3; endothelin-3
       K05244  GAL; galanin
       K25482  GALP; galanin-like peptide
       K25694  SPX; spexin
       K05254  GHRL; ghrelin
       K05265  MLN; motilin
       K05249  NMU; neuromedin U
       K25690  NMS; neuromedin S
       K05247  NPFF; neuropeptide FF-amide peptide
       K25692  NPVF; pro-FMRFamide-related neuropeptide VF
       K25691  NPS; neuropeptide S
       K05232  NPY; neuropeptide Y
       K05234  PPY; pancreatic polypeptide
       K05233  PYY; peptide YY
       K05267  NPB; preproneuropeptide B
       K23141  NPW; neuropeptide W
       K05228  POMC; proopiomelanocortin
       K18832  PENK; proenkephalin A
       K15840  PDYN, PENKB; proenkephalin B (prodynorphin)
       K25696  PNOC; prepronociceptin
       K25693  QRFP; orexigenic neuropeptide QRFP
       K05243  OXT; oxytocin-neurophysin 1
       K05237  SST; somatostatin
       K05238  CORT; cortistatin
       K05239  TAC1; tachykinin 1
       K05240  TAC3; tachykinin 3
       K05241  TAC4; tachykinin 4
       K05248  UTS2; urotensin 2
       K24267  UTS2B; urotensin-2B
       K05242  AVP; arginine vasopressin
       K05269  PRH; Prolactin-releasing peptide
       K23140  KISS1; metastasis-suppressor KiSS-1
       K05246  HCRT; hypocretin (orexin) neuropeptide
       K25695  VGF; neurosecretory protein VGF
       K19990  CHGA; chromogranin-A
       K19991  CHGB; chromogranin-B
       K25732  SCG2; secretogranin-2
       K25733  SCG3; secretogranin-3
       K25734  SCG5; neuroendocrine protein 7B2
       K05252  GNRH; gonadotropin-releasing hormone
       K05253  TRH; thyrotropin-releasing hormone
       K21998  RLN1_2; relaxin 1/2
       K22000  RLN3; relaxin 3
       K21999  INSL3; insulin-like 3
       K22001  INSL5; insulin-like 5
       K05229  PMCH; pro-melanin-concentrating hormone
       K13768  GAST; gastrin
       K12332  CALC; calcitonin
       K12333  ADM; adrenomedullin
       K25343  ADM2; adrenomedullin-2
       K08039  IAPP; islet amyloid polypeptide
       K05256  CRH; corticotropin-releasing hormone
       K23142  UCN; urcortin
       K05257  UCN2_3; urocortin 2/3
       K05258  GIP; gastric inhibitory polypeptide
       K05259  GCG; glucagon
       K05260  GHRH; growth hormone-releasing hormone
       K05261  PTH; parathyroid hormone
       K23143  PTH2, TIP39; tuberoinfundibular peptide of 39 residues
       K05262  ADCYAP; pituitary adenylate cyclase-activating polypeptide
       K05263  SCT; secretin
       K05264  VIP; vasoactive intestinal peptide
       K22608  PTHLH, PTHRP; parathyroid hormone-related hormone
       K08522  CGA; glycoprotein hormones alpha chain
       K05250  FSHB; follitropin subunit beta
       K08521  LHB; lutropin subunit beta
       K10045  CGB; chorionic gonadotropin, beta polypeptide
       K05251  TSHB; thyrotropin subunit beta
       K25483  GPHA2; glycoprotein hormone alpha-2
       K25484  GPHB5; glycoprotein hormone beta-5
       K12334  NPPA; natriuretic peptide A
       K12335  NPPB; natriuretic peptide B
       K12336  NPPC; natriuretic peptide C
       K16656  NXPH1; neurexophilin-1
       K16657  NXPH2; neurexophilin-2
       K16658  NXPH3; neurexophilin-3
       K25711  NXPH4; neurexophilin-4
       K04526  INS; insulin
       K05424  LEP; leptin
       K05439  PRL; prolactin
       K25453  CARTPT; cocaine- and amphetamine-regulated transcript protein
       K05231  AGRP; agouti related protein
       K08762  DBI, ACBP; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)
       K24235  CBLN; cerebellin
       K07296  ADIPOQ, ACDC; adiponectin
       K03462  NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12]
       K13438  RETN; resistin
       K20371  NUCB; nucleobindin
       K13113  UBL5, HUB1; ubiquitin-like protein 5

     04515 Cell adhesion molecules [BR:ko04515]

     04090 CD molecules [BR:ko04090]

     01504 Antimicrobial resistance genes [BR:ko01504]

     00535 Proteoglycans [BR:ko00535]

     00536 Glycosaminoglycan binding proteins [BR:ko00536]

     00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]

     04091 Lectins [BR:ko04091]

     04990 Domain-containing proteins not elsewhere classified [BR:ko04990]

 

   09185 Viral protein families

 

   09184 RNA family

 

 09190 Not Included in Pathway or Brite
[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 25, 2024