 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system [PATH:ko02020]
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04010 MAPK signaling pathway [PATH:ko04010]
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04013 MAPK signaling pathway - fly [PATH:ko04013]
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04016 MAPK signaling pathway - plant [PATH:ko04016]
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04011 MAPK signaling pathway - yeast [PATH:ko04011]
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04012 ErbB signaling pathway [PATH:ko04012]
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04014 Ras signaling pathway [PATH:ko04014]
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04015 Rap1 signaling pathway [PATH:ko04015]
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04310 Wnt signaling pathway [PATH:ko04310]
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04330 Notch signaling pathway [PATH:ko04330]
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04340 Hedgehog signaling pathway [PATH:ko04340]
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04341 Hedgehog signaling pathway - fly [PATH:ko04341]
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04350 TGF-beta signaling pathway [PATH:ko04350]
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04390 Hippo signaling pathway [PATH:ko04390]
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04391 Hippo signaling pathway - fly [PATH:ko04391]
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04392 Hippo signaling pathway - multiple species [PATH:ko04392]
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04370 VEGF signaling pathway [PATH:ko04370]
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04371 Apelin signaling pathway [PATH:ko04371]
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04630 JAK-STAT signaling pathway [PATH:ko04630]
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04064 NF-kappa B signaling pathway [PATH:ko04064]
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 K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K07371 BLNK; B-cell linker protein
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K20912 CARD10; caspase recruitment domain-containing protein 10
K07367 CARD11; caspase recruitment domain-containing protein 11
K20913 CARD14; caspase recruitment domain-containing protein 14
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K05480 EDA; ectodysplasin-A
K05162 EDAR; tumor necrosis factor receptor superfamily member EDAR
K23324 EDARADD; ectodysplasin-A receptor-associated adapter protein
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K05163 EDA2R, TNFRSF27, XEDAR; tumor necrosis factor receptor superfamily member 27
K12646 DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K10652 TRIM25, EFP; tripartite motif-containing protein 25 [EC:2.3.2.27]
K05399 LBP; lipopolysaccharide-binding protein
K04391 CD14; monocyte differentiation antigen CD14
K10160 TLR4, CD284; toll-like receptor 4
K05400 LY96, MD-2; lymphocyte antigen 96
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K05842 TRIF; toll-like receptor adapter molecule 1
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K03174 TRAF3; TNF receptor-associated factor 3
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05147 TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K05151 TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
K10577 UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K10130 LRDD, PIDD; leucine-rich repeats and death domain-containing protein
K16072 ERC1, CAST2, ELKS; ELKS/RAB6-interacting/CAST family member 1
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K27356 PPP1R13L; RelA-associated inhibitor
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K03172 TRAF1; TNF receptor-associated factor 1
K02162 BCL2A1; hematopoietic Bcl-2-related protein A1
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K10030 IL8, CXCL8; interleukin 8
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K12964 CCL4; C-C motif chemokine 4
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K09253 RELB; transcription factor RelB
K16595 CCL13; C-C motif chemokine 13
K05512 CCL19, ELC; C-C motif chemokine 19
K16062 CCL21, SLC; C-C motif chemokine 21
K10031 CXCL12; C-X-C motif chemokine 12
K06490 ICAM1, CD54; intercellular adhesion molecule 1
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04668 TNF signaling pathway [PATH:ko04668]
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04066 HIF-1 signaling pathway [PATH:ko04066]
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04068 FoxO signaling pathway [PATH:ko04068]
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04020 Calcium signaling pathway [PATH:ko04020]
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04070 Phosphatidylinositol signaling system [PATH:ko04070]
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04072 Phospholipase D signaling pathway [PATH:ko04072]
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04071 Sphingolipid signaling pathway [PATH:ko04071]
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04024 cAMP signaling pathway [PATH:ko04024]
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04022 cGMP-PKG signaling pathway [PATH:ko04022]
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04151 PI3K-Akt signaling pathway [PATH:ko04151]
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04152 AMPK signaling pathway [PATH:ko04152]
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04150 mTOR signaling pathway [PATH:ko04150]
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04075 Plant hormone signal transduction [PATH:ko04075]
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09133 Signaling molecules and interaction
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04080 Neuroactive ligand-receptor interaction [PATH:ko04080]
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04060 Cytokine-cytokine receptor interaction [PATH:ko04060]
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K05514 CCL1; C-C motif chemokine 1
K13072 CCL25; C-C motif chemokine 25
K05512 CCL19, ELC; C-C motif chemokine 19
K16062 CCL21, SLC; C-C motif chemokine 21
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K21083 CCL17; C-C motif chemokine 17
K21095 CCL22; C-C motif chemokine 22
K12499 CCL5; C-C motif chemokine 5
K16596 CCL8; C-C motif chemokine 8
K22671 CCL9; C-C motif chemokine 9
K21092 CCL14; C-C motif chemokine 14
K21093 CCL16; C-C motif chemokine 16
K05511 CCL15_23; C-C motif chemokine 15/23
K16595 CCL13; C-C motif chemokine 13
K05510 CCL6; C-C motif chemokine 6
K05509 CCL7; C-C motif chemokine 7
K14624 CCL2, MCP1; C-C motif chemokine 2
K16597 CCL11; C-C motif chemokine 11
K21097 CCL24; C-C motif chemokine 24
K21096 CCL26; C-C motif chemokine 26
K16598 CCL27; C-C motif chemokine 27
K05513 CCL28; C-C motif chemokine 28
K21094 CCL18; C-C motif chemokine 18
K14625 CCL20; C-C motif chemokine 20
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K10029 PPBP, CXCL7; platelet basic protein
K05407 PF4, CXCL4; platelet factor 4
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10032 CXCL13; C-X-C motif chemokine 13
K10031 CXCL12; C-X-C motif chemokine 12
K10035 CXCL16; C-X-C motif chemokine 16
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K10034 CXCL15; C-X-C motif chemokine 15
K22627 CXCL17; C-X-C motif chemokine 17
K05507 XCL1, SCM1; C motif chemokine 1
K22675 XCL2, SCM1B; C motif chemokine 2
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05433 IL15; interleukin 15
K05434 IL21; interleukin 21
K05436 TSLP; thymic stromal lymphopoietin
K04736 IL3; interleukin 3
K05428 IL5; interleukin 5
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05435 IL13; interleukin 13
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K05439 PRL; prolactin
K06854 THPO; thrombopoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05424 LEP; leptin
K05405 IL6; interleukin 6
K05417 IL11; interleukin 11
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05426 IL23A; interleukin 23 subunit alpha
K22629 IL27, IL27A; interleukin 27 subunit alpha
K24476 EBI3, IL27B; interleukin 27 subunit beta
K22631 IL31; interleukin 31
K05421 CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
K05420 CNTF; ciliary neurotrophic factor
K05422 CTF1, CT1; cardiotrophin 1
K24382 CTF2; cardiotrophin 2
K05419 LIF; leukemia inhibitory factor
K05418 OSM; oncostatin M
K05443 IL10, CSIF; interleukin 10
K05444 IL19; interleukin 19
K22667 IL20; interleukin 20
K22668 IL24; interleukin 24
K05445 IL22, IL-TIF; interleukin 22
K05446 IL26; interleukin 26
K22669 IFNL2_3, IL28; interferon lambda 2/3
K05447 IFNL1, IL29; interferon lambda 1
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05440 IFNW; interferon omega
K05441 IFNK; interferon kappa
K05442 IFNE; interferon epsilon
K04687 IFNG; interferon gamma
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05481 IL1RN, IL1F3; interleukin 1 receptor antagonist
K05483 IL36RN, IL1F5; interleukin 36 receptor antagonist protein
K05484 IL36A, IL1F6; interleukin 36 alpha
K05486 IL36B, IL1F8; interleukin 36 beta
K05487 IL36G, IL1F9; interleukin 36 gamma
K05488 IL1F10, FKSG75; interleukin 1 family member 10
K05485 IL37, IL1F7; interleukin 37
K05482 IL18, IL1F4; interleukin 18
K12967 IL33; interleukin 33
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05490 IL17B, CX1; interleukin 17B
K05491 IL17C, CX2; interleukin 17C
K05492 IL17D, IL27; interleukin 17D
K05493 IL17E, IL25; interleukin 17E
K22628 IL16; interleukin 16
K22632 IL32; interleukin 32
K22633 IL34; interleukin 34
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K05478 TNFSF15, VEGI; tumor necrosis factor ligand superfamily member 15
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K05480 EDA; ectodysplasin-A
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05474 TNFSF12, TWEAK; tumor necrosis factor ligand superfamily member 12
K05470 TNFSF7, CD70; tumor necrosis factor ligand superfamily member 7
K05471 TNFSF8, CD153; tumor necrosis factor ligand superfamily member 8
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K05472 TNFSF9, CD137L; tumor necrosis factor ligand superfamily member 9
K05469 TNFSF4, OX40L, CD252; tumor necrosis factor ligand superfamily member 4
K05479 TNFSF18, GITRL; tumor necrosis factor ligand superfamily member 18
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K05504 GDF15; growth differentiation factor 15
K05503 GDF2, BMP9; growth differentiation factor 2
K22670 BMP10; bone morphogenetic protein 10
K05500 INHA; inhibin, alpha
K05496 BMP3; bone morphogenetic protein 3
K22674 GDF10, BMP3B; growth differentiation factor 10
K22679 GDF11; growth differentiation factor 11
K05497 MSTN, GDF8; growth differentiation factor 8
K04667 INHBA; inhibin beta A chain
K22687 INHBB; inhibin beta B chain
K05495 GDF1; growth differentiation factor 1
K22672 GDF3; growth differentiation factor 3
K04666 NODAL; nodal
K22673 GDF9; growth differentiation factor 9
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04665 AMH; anti-mullerian hormone
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K05498 BMP15, GDF9B; bone morphogenetic protein 15
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K04184 CCR9, CDw199; C-C chemokine receptor type 9
K04186 ACKR4, CCRL1, CCR11; atypical chemokine receptor 4
K04182 CCR7, CD197; C-C chemokine receptor type 7
K04179 CCR4, CD194; C-C chemokine receptor type 4
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04177 CCR2, CD192; C-C chemokine receptor type 2
K04176 CCR1, CD191; C-C chemokine receptor type 1
K04185 CCR10; C-C chemokine receptor type 10
K04181 CCR6, CD196; C-C chemokine receptor type 6
K04175 CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K04188 CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
K04190 CXCR5, BLR1, CD185; C-X-C chemokine receptor type 5
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04304 CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
K04191 CXCR6, CD186; C-X-C chemokine receptor type 6
K04193 XCR1; XC chemokine receptor 1
K04192 CX3CR1; CX3C chemokine receptor 1
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K05071 IL4R, CD124; interleukin 4 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05073 IL9R, CD129; interleukin 9 receptor
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05075 IL21R, CD360; interleukin 21 receptor
K05078 TSLPR; thymic stromal-derived lymphopoietin receptor
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05077 IL13RA2, CD213A2; interleukin 13 receptor alpha-2
K05079 EPOR; erythropoietin receptor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05082 TPOR, MPL, CD110; thrombopoietin receptor
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05062 LEPR, CD295; leptin receptor
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05056 IL11RA; interleukin 11 receptor alpha
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05065 IL23R; interleukin 23 receptor
K19598 IL27RA; interleukin 27 receptor alpha
K22630 IL31RA; interleukin 31 receptor subunit alpha
K05059 CNTFR; ciliary neurotrophic factor receptor
K05058 LIFR, CD118; leukemia inhibitory factor receptor
K05057 OSMR; oncostatin M receptor
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K05136 IL20RA; interleukin 20 receptor alpha
K05137 IL20RB; interleukin 20 receptor beta
K05138 IL22RA1; interleukin 22 receptor alpha 1
K05140 IFNLR1, IL28RA; interferon lambda receptor 1
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K05172 IL1RL2, IL1RRP2; interleukin 1 receptor-like 2
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K05174 IL18RAP, ACPL, CD218b; interleukin 18 receptor accessory protein
K05171 IL1RL1, ST2; interleukin 1 receptor-like 1
K05164 IL17RA, CD217; interleukin 17 receptor A
K05166 IL17RC, IL17RL; interleukin 17 receptor C
K05165 IL17RB, IL17RH1; interleukin 17 receptor B
K05168 IL17RE; interleukin 17 receptor E
K06454 CD4; T-cell surface glycoprotein CD4
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K05152 TNFRSF14, HVEM, CD270; tumor necrosis factor receptor superfamily member 14
K05143 TNFRSF6B, DCR3; tumor necrosis factor receptor superfamily member 6B
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K05160 TNFRSF25; tumor necrosis factor receptor superfamily member 25
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K22701 TNFRSF10C, TRAILR3, DCR1, CD263; tumor necrosis factor receptor superfamily member 10C
K22702 TNFRSF10D, TRAILR4, DCR2, CD264; tumor necrosis factor receptor superfamily member 10D
K05157 TNFRSF21, DR6, CD358; tumor necrosis factor receptor superfamily member 21
K05162 EDAR; tumor necrosis factor receptor superfamily member EDAR
K05163 EDA2R, TNFRSF27, XEDAR; tumor necrosis factor receptor superfamily member 27
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K05148 TNFRSF11B, OPG; tumor necrosis factor receptor superfamily member 11B
K05147 TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
K05149 TNFRSF12A, FN14, TWEAKR, CD266; tumor necrosis factor receptor superfamily member 12A
K05144 TNFRSF7, CD27; tumor necrosis factor receptor superfamily member 7
K05145 TNFRSF8, CD30; tumor necrosis factor receptor superfamily member 8
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05146 TNFRSF9, CD137; tumor necrosis factor receptor superfamily member 9
K05142 TNFRSF4, OX40, CD134; tumor necrosis factor receptor superfamily member 4
K05154 TNFRSF18, GITR, CD357; tumor necrosis factor receptor superfamily member 18
K05153 TNFRSF17, BCMA, CD269; tumor necrosis factor receptor superfamily member 17
K05150 TNFRSF13B, TACI, CD267; tumor necrosis factor receptor superfamily member 13B
K05151 TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
K05155 TNFRSF19, TROY; tumor necrosis factor receptor superfamily member 19
K05156 RELT, TNFRSF19L; tumor necrosis factor receptor superfamily member 19-like
K26541 RELL; RELT-like protein
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K13594 ACVRL1, ALK1; activin receptor-like kinase 1 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K13567 ACVR1B, ALK4; activin receptor type-1B [EC:2.7.11.30]
K13568 ACVR1C, ALK7; activin receptor type-1C [EC:2.7.11.30]
K04675 ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
K04672 AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
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04061 Viral protein interaction with cytokine and cytokine receptor [PATH:ko04061]
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K23381 vCCI; Poxvirus chemokine inhibitor
K22784 UL22A; HCMV glycoprotein UL22A
K23382 gG; Simplexvirus envelope glycoprotein G
K21538 vTNFR2; Poxvirus tumor necrosis factor receptor II
K22973 BARF1; Lymphocryptovirus secreted protein BARF1
K12499 CCL5; C-C motif chemokine 5
K05408 CCL3; C-C motif chemokine 3
K16596 CCL8; C-C motif chemokine 8
K22671 CCL9; C-C motif chemokine 9
K21092 CCL14; C-C motif chemokine 14
K21093 CCL16; C-C motif chemokine 16
K05511 CCL15_23; C-C motif chemokine 15/23
K16595 CCL13; C-C motif chemokine 13
K05510 CCL6; C-C motif chemokine 6
K05509 CCL7; C-C motif chemokine 7
K21657 K4; KSHV macrophage inflammatory protein 2
K22624 vCCL27; MOCV1 CC chemokine receptor antagonist
K23392 vCCL4a, U83; HHV6 CCRs chemokine agonist
K21040 vCCL4b, U83; HHV6 CCR2 chemokine agonist
K14624 CCL2, MCP1; C-C motif chemokine 2
K16598 CCL27; C-C motif chemokine 27
K16597 CCL11; C-C motif chemokine 11
K21097 CCL24; C-C motif chemokine 24
K21096 CCL26; C-C motif chemokine 26
K05513 CCL28; C-C motif chemokine 28
K21083 CCL17; C-C motif chemokine 17
K21095 CCL22; C-C motif chemokine 22
K21658 K4.1; KSHV protein vCCL3
K12964 CCL4; C-C motif chemokine 4
K21659 K6; KSHV protein K6
K24266 gp120; HIV envelope glycoprotein gp120
K14625 CCL20; C-C motif chemokine 20
K05514 CCL1; C-C motif chemokine 1
K13072 CCL25; C-C motif chemokine 25
K21094 CCL18; C-C motif chemokine 18
K05512 CCL19, ELC; C-C motif chemokine 19
K16062 CCL21, SLC; C-C motif chemokine 21
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K21046 UL146; HCMV chemokine vCXCL1
K10029 PPBP, CXCL7; platelet basic protein
K05407 PF4, CXCL4; platelet factor 4
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10032 CXCL13; C-X-C motif chemokine 13
K10031 CXCL12; C-X-C motif chemokine 12
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K05507 XCL1, SCM1; C motif chemokine 1
K22675 XCL2, SCM1B; C motif chemokine 2
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05443 IL10, CSIF; interleukin 10
K21533 vIL10; Herpesviridae/Poxviridae viral interleukin 10
K05405 IL6; interleukin 6
K21670 vIL6, K2; KSHV interleukin 6
K05429 IL2; interleukin 2
K23069 p12I; HTLV-1 accessory protein p12I
K05482 IL18, IL1F4; interleukin 18
K05485 IL37, IL1F7; interleukin 37
K05444 IL19; interleukin 19
K22667 IL20; interleukin 20
K22668 IL24; interleukin 24
K23426 134R; YLDV 134R protein
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K21807 E6; Alphapapillomavirus protein E6
K23428 2L; TPV TNF binding protein 2L
K19264 gD; Simplexvirus envelope glycoprotein D
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K21049 UL141; Cytomegalovirus protein UL141
K22633 IL34; interleukin 34
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K04176 CCR1, CD191; C-C chemokine receptor type 1
K22781 US28; HCMV envelope protein US28
K23431 HHV6-U12; HHV6 CC-chemokine receptor U12
K04177 CCR2, CD192; C-C chemokine receptor type 2
K23433 HHV6-U51; HHV6 G-protein coupled receptor homolog U51
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04179 CCR4, CD194; C-C chemokine receptor type 4
K23432 HHV7-U12; HHV7 CC-chemokine receptor U12
K23434 HHV7-U51; HHV7 G-protein coupled receptor homolog U51
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04181 CCR6, CD196; C-C chemokine receptor type 6
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K21667 vGPCR; KSHV G-protein coupled receptor
K23427 7L; Poxvirus chemokine receptor 7L
K04184 CCR9, CDw199; C-C chemokine receptor type 9
K04186 ACKR4, CCRL1, CCR11; atypical chemokine receptor 4
K04185 CCR10; C-C chemokine receptor type 10
K04182 CCR7, CD197; C-C chemokine receptor type 7
K04175 CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K04188 CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
K04190 CXCR5, BLR1, CD185; C-X-C chemokine receptor type 5
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04304 CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
K04193 XCR1; XC chemokine receptor 1
K04192 CX3CR1; CX3C chemokine receptor 1
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K05174 IL18RAP, ACPL, CD218b; interleukin 18 receptor accessory protein
K05136 IL20RA; interleukin 20 receptor alpha
K05137 IL20RB; interleukin 20 receptor beta
K05138 IL22RA1; interleukin 22 receptor alpha 1
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K05152 TNFRSF14, HVEM, CD270; tumor necrosis factor receptor superfamily member 14
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K22701 TNFRSF10C, TRAILR3, DCR1, CD263; tumor necrosis factor receptor superfamily member 10C
K22702 TNFRSF10D, TRAILR4, DCR2, CD264; tumor necrosis factor receptor superfamily member 10D
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
|
04512 ECM-receptor interaction [PATH:ko04512]
|
04514 Cell adhesion molecules [PATH:ko04514]
|
|
09140 Cellular Processes
|
|
09141 Transport and catabolism
|
|
09143 Cell growth and death
|
|
09144 Cellular community - eukaryotes
|
|
09145 Cellular community - prokaryotes
|
|
09142 Cell motility
|
02030 Bacterial chemotaxis [PATH:ko02030]
|
02040 Flagellar assembly [PATH:ko02040]
|
04814 Motor proteins [PATH:ko04814]
|
04820 Cytoskeleton in muscle cells [PATH:ko04820]
|
04810 Regulation of actin cytoskeleton [PATH:ko04810]
|
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04526 INS; insulin
K04357 EGF; epidermal growth factor
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05717 FN1; fibronectin 1
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV, CD51; integrin alpha V
K05718 ITGAL, CD11a; integrin alpha L
K06461 ITGAM, CD11b; integrin alpha M
K06462 ITGAX, CD11c; integrin alpha X
K06594 ITGAD, CD11d; integrin alpha D
K06524 ITGAE, CD103; integrin alpha E
K05719 ITGB1, CD29; integrin beta 1
K06464 ITGB2, CD18; integrin beta 2
K06493 ITGB3, CD61; integrin beta 3
K06525 ITGB4, CD104; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K03898 KNG, BK; kininogen
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04132 CHRM4; muscarinic acetylcholine receptor M4
K04133 CHRM5; muscarinic acetylcholine receptor M5
K03994 C5; complement component 5
K03995 C6; complement component 6
K03996 C7; complement component 7
K03997 C8A; complement component 8 subunit alpha
K03998 C8B; complement component 8 subunit beta
K03999 C8G; complement component 8 subunit gamma
K04000 C9; complement component 9
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K05720 FGD1; FYVE, RhoGEF and PH domain containing 1
K05722 FGD3; FYVE, RhoGEF and PH domain containing 3
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K05729 ARHGEF6, PIXA; Rho guanine nucleotide exchange factor 6
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05730 VAV; guanine nucleotide exchange factor VAV
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K26108 RGCC, RGC32; regulator of cell cycle RGCC
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K05732 ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
K04513 RHOA; Ras homolog gene family, member A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K13710 ARHGEF7, PIXB; Rho guanine nucleotide exchange factor 7
K05737 GIT1; G protein-coupled receptor kinase interactor 1
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K10352 MYH9s; myosin heavy chain 9/10/11/14
K05740 DIAPH1; diaphanous 1
K05741 DIAPH2; diaphanous 2
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00920 PIP4K2; 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]
K00921 PIKFYVE, FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05745 DIAPH3, DRF3; diaphanous 3
K05627 BAIAP2, IRSP53; BAI1-associated protein 2
K05746 ENAH, MENA; enabled
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K05748 WASF2; WAS protein family, member 2
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K05750 NCKAP1, NAP125; NCK-associated protein 1
K05751 ABI2; abl interactor 2
K05752 C3ORF10, HSPC300; chromosome 3 open reading frame 10
K05753 WASF1; WAS protein family, member 1
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K05759 PFN; profilin
K05760 PXN; paxillin
K08007 EZR, VIL2; ezrin
K05762 RDX; radixin
K05763 MSN; moesin
K05764 TMSB4; thymosin, beta 4
K05765 CFL; cofilin
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K05700 VCL; vinculin
K16848 IQGAP1; Ras GTPase-activating-like protein IQGAP1
K05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
K05768 GSN; gelsolin
K05699 ACTN1_4; actinin alpha 1/4
K02085 APC; adenomatosis polyposis coli protein
K05769 ARHGEF4_29, ASEF1_2; Rho guanine nucleotide exchange factor 4/29
|
|
09150 Organismal Systems
|
|
09151 Immune system
|
04640 Hematopoietic cell lineage [PATH:ko04640]
|
04610 Complement and coagulation cascades [PATH:ko04610]
|
04611 Platelet activation [PATH:ko04611]
|
04613 Neutrophil extracellular trap formation [PATH:ko04613]
|
04620 Toll-like receptor signaling pathway [PATH:ko04620]
|
04624 Toll and Imd signaling pathway [PATH:ko04624]
|
04621 NOD-like receptor signaling pathway [PATH:ko04621]
|
04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
|
04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
|
04625 C-type lectin receptor signaling pathway [PATH:ko04625]
|
04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
|
04612 Antigen processing and presentation [PATH:ko04612]
|
04660 T cell receptor signaling pathway [PATH:ko04660]
|
04658 Th1 and Th2 cell differentiation [PATH:ko04658]
|
04659 Th17 cell differentiation [PATH:ko04659]
|
04657 IL-17 signaling pathway [PATH:ko04657]
|
04662 B cell receptor signaling pathway [PATH:ko04662]
|
04664 Fc epsilon RI signaling pathway [PATH:ko04664]
|
04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
|
04670 Leukocyte transendothelial migration [PATH:ko04670]
|
K06785 JAM3; junctional adhesion molecule 3
K06461 ITGAM, CD11b; integrin alpha M
K06464 ITGB2, CD18; integrin beta 2
K06735 JAM2, CD322; junctional adhesion molecule 2
K06483 ITGA4, CD49d; integrin alpha 4
K05719 ITGB1, CD29; integrin beta 1
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K06520 CD99, MIC2; CD99 antigen
K05718 ITGAL, CD11a; integrin alpha L
K06089 F11R, JAM1, CD321; junctional adhesion molecule 1
K06533 CDH5, CD144; cadherin 5, type 2, VE-cadherin
K06087 CLDN; claudin
K06088 OCLN; occludin
K06787 ESAM; endothelial cell adhesion molecule
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K08007 EZR, VIL2; ezrin
K05763 MSN; moesin
K05692 ACTB_G1; actin beta/gamma 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K02105 CTNNB1; catenin beta 1
K05690 CTNND1; catenin (cadherin-associated protein), delta 1
K05691 CTNNA; catenin alpha
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05760 PXN; paxillin
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K06514 THY1, CD90; Thy-1 cell surface antigen
K05732 ARHGAP35, GRLF1; glucocorticoid receptor DNA-binding factor 1
K13709 ARHGAP5; Rho GTPase-activating protein 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K05702 AF6, MLLT4; afadin
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K08013 SIPA1; signal-induced proliferation-associated gene 1
K06274 VASP; vasodilator-stimulated phosphoprotein
K05699 ACTN1_4; actinin alpha 1/4
K05700 VCL; vinculin
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08014 RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K08016 TXK, RLK; tyrosine-protein kinase TXK [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K04393 CDC42; cell division control protein 42
K07873 RHOH, TTF; Ras homolog gene family, member H
|
04672 Intestinal immune network for IgA production [PATH:ko04672]
|
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06752 MHC2; MHC class II antigen
K06470 CD28; CD28 antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05443 IL10, CSIF; interleukin 10
K13375 TGFB1; transforming growth factor beta-1
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K05150 TNFRSF13B, TACI, CD267; tumor necrosis factor receptor superfamily member 13B
K05153 TNFRSF17, BCMA, CD269; tumor necrosis factor receptor superfamily member 17
K05151 TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
K06856 IGH; immunoglobulin heavy chain
K10989 AICDA, AID; activation-induced cytidine deaminase [EC:3.5.4.38]
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K06713 ICOS, AILIM, CD278; inducible T-cell co-stimulator
K06710 ICOSLG, ICOSL, CD275; inducible T-cell co-stimulator ligand
K04184 CCR9, CDw199; C-C chemokine receptor type 9
K06483 ITGA4, CD49d; integrin alpha 4
K06590 ITGB7; integrin beta 7
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K05513 CCL28; C-C motif chemokine 28
K04185 CCR10; C-C chemokine receptor type 10
K13072 CCL25; C-C motif chemokine 25
K06779 MADCAM1; mucosal vascular addressin cell adhesion molecule 1
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K05433 IL15; interleukin 15
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K13073 PIGR; polymeric immunoglobulin receptor
|
04062 Chemokine signaling pathway [PATH:ko04062]
|
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10029 PPBP, CXCL7; platelet basic protein
K10030 IL8, CXCL8; interleukin 8
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10031 CXCL12; C-X-C motif chemokine 12
K10032 CXCL13; C-X-C motif chemokine 13
K10035 CXCL16; C-X-C motif chemokine 16
K10034 CXCL15; C-X-C motif chemokine 15
K05407 PF4, CXCL4; platelet factor 4
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K05507 XCL1, SCM1; C motif chemokine 1
K22675 XCL2, SCM1B; C motif chemokine 2
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05514 CCL1; C-C motif chemokine 1
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K12499 CCL5; C-C motif chemokine 5
K05510 CCL6; C-C motif chemokine 6
K05509 CCL7; C-C motif chemokine 7
K16596 CCL8; C-C motif chemokine 8
K22671 CCL9; C-C motif chemokine 9
K16597 CCL11; C-C motif chemokine 11
K16595 CCL13; C-C motif chemokine 13
K21092 CCL14; C-C motif chemokine 14
K05511 CCL15_23; C-C motif chemokine 15/23
K21093 CCL16; C-C motif chemokine 16
K21083 CCL17; C-C motif chemokine 17
K21094 CCL18; C-C motif chemokine 18
K05512 CCL19, ELC; C-C motif chemokine 19
K14625 CCL20; C-C motif chemokine 20
K16062 CCL21, SLC; C-C motif chemokine 21
K21095 CCL22; C-C motif chemokine 22
K21097 CCL24; C-C motif chemokine 24
K13072 CCL25; C-C motif chemokine 25
K21096 CCL26; C-C motif chemokine 26
K16598 CCL27; C-C motif chemokine 27
K05513 CCL28; C-C motif chemokine 28
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K04175 CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
K04188 CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04190 CXCR5, BLR1, CD185; C-X-C chemokine receptor type 5
K04191 CXCR6, CD186; C-X-C chemokine receptor type 6
K04193 XCR1; XC chemokine receptor 1
K04192 CX3CR1; CX3C chemokine receptor 1
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K04181 CCR6, CD196; C-C chemokine receptor type 6
K04184 CCR9, CDw199; C-C chemokine receptor type 9
K04179 CCR4, CD194; C-C chemokine receptor type 4
K04182 CCR7, CD197; C-C chemokine receptor type 7
K04177 CCR2, CD192; C-C chemokine receptor type 2
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04176 CCR1, CD191; C-C chemokine receptor type 1
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04185 CCR10; C-C chemokine receptor type 10
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11224 STAT5B; signal transducer and activator of transcription 5B
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K08891 FGR, SRC2; tyrosine-protein kinase Fgr [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K09408 FOXO3; forkhead box protein O3
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02158 BAD; Bcl-2-antagonist of cell death
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04393 CDC42; cell division control protein 42
K05747 WAS; Wiskott-Aldrich syndrome protein
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K12365 PREX1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein
K12366 ELMO1, CED12; engulfment and cell motility protein 1
K12367 DOCK2; dedicator of cytokinesis protein 2
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05760 PXN; paxillin
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K12361 RASGRP2; RAS guanyl-releasing protein 2
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04237 PARD3; partitioning defective protein 3
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
K00910 ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K04439 ARRB; beta-arrestin
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|
09152 Endocrine system
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09153 Circulatory system
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09154 Digestive system
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09155 Excretory system
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09156 Nervous system
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09157 Sensory system
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|
09158 Development and regeneration
|
04320 Dorso-ventral axis formation [PATH:ko04320]
|
04360 Axon guidance [PATH:ko04360]
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K07522 NTNG1; netrin-G1
K16359 NTNG2; netrin-G2
K07523 LRRC4C, NGL1; netrin-G1 ligand
K16351 LRRC4, NGL2; netrin-G2 ligand
K06843 NTN1; netrin 1
K06844 NTN3; netrin 3
K06845 NTN4; netrin 4
K06765 DCC; deleted in colorectal carcinoma
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04964 TRPC1; transient receptor potential cation channel subfamily C member 1
K04966 TRPC3; transient receptor potential cation channel subfamily C member 3
K04967 TRPC4; transient receptor potential cation channel subfamily C member 4
K04968 TRPC5; transient receptor potential cation channel subfamily C member 5
K04969 TRPC6; transient receptor potential cation channel subfamily C member 6
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K07520 ABLIM; actin-binding LIM protein
K07365 NCK1; NCK adaptor protein 1
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K07521 UNC5; netrin receptor unc-5
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K23096 RGMA; repulsive guidance molecule A
K06766 NEO1; neogenin
K12753 MYL5; myosin regulatory light chain 5
K12755 MYL9; myosin regulatory light chain 9
K12757 MYL12; myosin regulatory light chain 12
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K24609 LRIG2; leucine-rich repeats and immunoglobulin-like domains protein 2
K05462 EFNA; ephrin-A
K05463 EFNB; ephrin-B
K05102 EPHA1, EPH; Eph receptor A1 [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K05104 EPHA3, HEK, TYRO4; Eph receptor A3 [EC:2.7.10.1]
K05105 EPHA4, SEK, TYRO1; Eph receptor A4 [EC:2.7.10.1]
K05106 EPHA5, EHK1, TYRO4; Eph receptor A5 [EC:2.7.10.1]
K05107 EPHA6, EHK2; Eph receptor A6 [EC:2.7.10.1]
K05108 EPHA7, EHK3, HEK11; EphA7 [EC:2.7.10.1]
K05109 EPHA8, EEK; Eph receptor A8 [EC:2.7.10.1]
K05110 EPHB1, ELK, NET; Eph receptor B1 [EC:2.7.10.1]
K05111 EPHB2, ERK, DRT; Eph receptor B2 [EC:2.7.10.1]
K05112 EPHB3, HEK2, ETK2; Eph receptor B3 [EC:2.7.10.1]
K05113 EPHB4, HTK; Eph receptor B4 [EC:2.7.10.1]
K05114 EPHB6; Eph receptor B6 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K05746 ENAH, MENA; enabled
K04352 RASA1, RASGAP; Ras GTPase-activating protein 1
K07525 NGEF, EPHEXIN, ARHGEF27; neuronal guanine nucleotide exchange factor
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K19862 NCK2, GRB4; NCK adaptor protein 2
K07524 RGS3; regulator of G-protein signalling 3
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K06838 SLIT1; slit 1
K06839 SLIT2; slit 2
K06850 SLIT3; slit 3
K06753 ROBO1; roundabout, axon guidance receptor 1
K06754 ROBO2; roundabout, axon guidance receptor 2
K06755 ROBO3; roundabout, axon guidance receptor 3
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein
K06840 SEMA3; semaphorin 3
K06820 PLXNA; plexin A
K06724 NRP1, CD304; neuropilin 1
K06550 L1CAM, CD171; L1 cell adhesion molecule
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05765 CFL; cofilin
K07530 RHOD; Ras homolog gene family, member D
K07531 RND1; Rho family GTPase 1
K07527 FES, FPS; tyrosine-protein kinase Fes/Fps [EC:2.7.10.2]
K07529 DPYSL5, CRAM; dihydropyrimidinase-like 5
K07528 DPYSL2, CRMP2; dihydropyrimidinase-like 2
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06521 SEMA4, CD100; semaphorin 4
K06841 SEMA5; semaphorin 5
K06842 SEMA6; semaphorin 6
K06821 PLXNB; plexin B
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07829 RRAS; Ras-related protein R-Ras
K06529 SEMA7, CD108; semaphorin 7
K06572 PLXNC, CD232; plexin C
K05719 ITGB1, CD29; integrin beta 1
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K20020 BOC; brother of CDO
K00444 WNT5; wingless-type MMTV integration site family, member 5
K02329 FZD3; frizzled 3
K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04237 PARD3; partitioning defective protein 3
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06093 PARD6; partitioning defective protein 6
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K16621 BMP7; bone morphogenetic protein 7
K20013 GDF7; growth differentiation factor 7
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
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04361 Axon regeneration [PATH:ko04361]
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04380 Osteoclast differentiation [PATH:ko04380]
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09149 Aging
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09159 Environmental adaptation
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09160 Human Diseases
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|
09161 Cancer: overview
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05200 Pathways in cancer [PATH:ko05200]
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1, DIP13A; DCC-interacting protein 13 alpha
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT, SERPINA8; angiotensinogen
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04236 F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06485 ITGA6, CD49f; integrin alpha 6
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K08878 BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG, BK; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05071 IL4R, CD124; interleukin 4 receptor
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05072 IL7R, CD127; interleukin 7 receptor
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1, pnt; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8, CXCL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6, PTC; coiled-coil domain-containing protein 6
K09289 NCOA4, PTC3; nuclear receptor coactivator 4
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR, MLP1, MLP2; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K04411 STK4, MST1; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K08528 RARB, NR1B2; retinoic acid receptor beta
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K09101 NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K10056 JUP, PG; junction plakoglobin
K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K08527 RARA, NR1B1; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 RUNX1, AML1; runt-related transcription factor 1
K10053 RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03347 CUL1, CDC53; cullin 1
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3, PUMA; Bcl-2-binding component 3
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC, TCEB1; elongin-C
K03873 ELOB, TCEB2; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1, CD339; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR, NR3C4; androgen receptor
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K01351 KLK3, PSA; semenogelase [EC:3.4.21.77]
|
05202 Transcriptional misregulation in cancer [PATH:ko05202]
|
05206 MicroRNAs in cancer [PATH:ko05206]
|
05205 Proteoglycans in cancer [PATH:ko05205]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
|
05203 Viral carcinogenesis [PATH:ko05203]
|
05230 Central carbon metabolism in cancer [PATH:ko05230]
|
05231 Choline metabolism in cancer [PATH:ko05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
|
|
09162 Cancer: specific types
|
|
09172 Infectious disease: viral
|
05166 Human T-cell leukemia virus 1 infection [PATH:ko05166]
|
05170 Human immunodeficiency virus 1 infection [PATH:ko05170]
|
05161 Hepatitis B [PATH:ko05161]
|
05160 Hepatitis C [PATH:ko05160]
|
05171 Coronavirus disease - COVID-19 [PATH:ko05171]
|
05164 Influenza A [PATH:ko05164]
|
05162 Measles [PATH:ko05162]
|
05168 Herpes simplex virus 1 infection [PATH:ko05168]
|
05163 Human cytomegalovirus infection [PATH:ko05163]
|
K22773 gB, UL55; Betaherpesvirinae envelope glycoprotein B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K22774 UL123; HCMV immediate-early protein 1
K22775 UL122; Cytomegalovirus viral transcription factor IE2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K22776 UL38; Cytomegalovirus apoptosis inhibitor UL38
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04684 SP1; transcription factor Sp1
K22777 gH, UL75; Cytomegalovirus envelope glycoprotein H
K22778 gL, UL115; Cytomegalovirus envelope glycoprotein L
K06487 ITGAV, CD51; integrin alpha V
K06493 ITGB3, CD61; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K22779 UL82; Cytomegalovirus tegument protein pp71
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K09849 TRAF5; TNF receptor-associated factor 5
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K22780 UL26; Cytomegalovirus tegument protein UL26
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K10030 IL8, CXCL8; interleukin 8
K05405 IL6; interleukin 6
K22781 US28; HCMV envelope protein US28
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K16529 ARHGEF13; A-kinase anchor protein 13
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K02105 CTNNB1; catenin beta 1
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
K05055 IL6R, CD126; interleukin 6 receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05448 VEGFA; vascular endothelial growth factor A
K22782 UL33; Cytomegalovirus G-protein coupled receptor UL33
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K22783 US27; HCMV envelope glycoprotein US27
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; C-crk adapter molecule crk
K05760 PXN; paxillin
K21533 vIL10; Herpesviridae/Poxviridae viral interleukin 10
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K21046 UL146; HCMV chemokine vCXCL1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K22784 UL22A; HCMV glycoprotein UL22A
K04176 CCR1, CD191; C-C chemokine receptor type 1
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04180 CCR5, CD195; C-C chemokine receptor type 5
K22785 US6; HCMV membrane glycoprotein US6
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K21050 US2; HCMV unique short US2 glycoprotein
K22786 US11; HCMV membrane glycoprotein US11
K22787 US3; HCMV membrane glycoprotein US3
K21051 US10; HCMV unique short US10 glycoprotein
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K22788 UL36; Cytomegalovirus viral inhibitor of caspase-8-induced apoptosis
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K22789 UL37; UL37 HCMV immediate early glycoprotein
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
|
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:ko05167]
|
05169 Epstein-Barr virus infection [PATH:ko05169]
|
05165 Human papillomavirus infection [PATH:ko05165]
|
|
09171 Infectious disease: bacterial
|
|
09174 Infectious disease: parasitic
|
|
09163 Immune disease
|
05310 Asthma [PATH:ko05310]
|
05322 Systemic lupus erythematosus [PATH:ko05322]
|
05323 Rheumatoid arthritis [PATH:ko05323]
|
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K06538 CTLA4, CD152; cytotoxic T-lymphocyte-associated protein 4
K06752 MHC2; MHC class II antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05718 ITGAL, CD11a; integrin alpha L
K06464 ITGB2, CD18; integrin beta 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K05433 IL15; interleukin 15
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K06856 IGH; immunoglobulin heavy chain
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05417 IL11; interleukin 11
K05482 IL18, IL1F4; interleukin 18
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K05426 IL23A; interleukin 23 subunit alpha
K05489 IL17A, CTLA8; interleukin 17A
K05261 PTH; parathyroid hormone
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05147 TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
K02145 ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:7.1.2.2]
K02147 ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
K02148 ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C
K02149 ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D
K02150 ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
K02151 ATPeV1F, ATP6S14; V-type H+-transporting ATPase subunit F
K02152 ATPeV1G, ATP6G; V-type H+-transporting ATPase subunit G
K02153 ATPeV0E, ATP6H; V-type H+-transporting ATPase subunit e
K02154 ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
K02146 ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K03662 ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
K02155 ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
K03661 ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
K01371 CTSK; cathepsin K [EC:3.4.22.38]
K14379 ACP5; tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K12499 CCL5; C-C motif chemokine 5
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K14625 CCL20; C-C motif chemokine 20
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K10031 CXCL12; C-X-C motif chemokine 12
K05448 VEGFA; vascular endothelial growth factor A
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05465 ANGPT1; angiopoietin 1
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K04687 IFNG; interferon gamma
|
05320 Autoimmune thyroid disease [PATH:ko05320]
|
05321 Inflammatory bowel disease [PATH:ko05321]
|
05330 Allograft rejection [PATH:ko05330]
|
05332 Graft-versus-host disease [PATH:ko05332]
|
05340 Primary immunodeficiency [PATH:ko05340]
|
|
09164 Neurodegenerative disease
|
|
09165 Substance dependence
|
|
09166 Cardiovascular disease
|
|
09167 Endocrine and metabolic disease
|
|
09175 Drug resistance: antimicrobial
|
|
09176 Drug resistance: antineoplastic
|
|
09180 Brite Hierarchies
|
|
09181 Protein families: metabolism
|
|
09182 Protein families: genetic information processing
|
|
09183 Protein families: signaling and cellular processes
|
02000 Transporters [BR:ko02000]
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02044 Secretion system [BR:ko02044]
|
02042 Bacterial toxins [BR:ko02042]
|
02022 Two-component system [BR:ko02022]
|
02035 Bacterial motility proteins [BR:ko02035]
|
03037 Cilium and associated proteins [BR:ko03037]
|
04812 Cytoskeleton proteins [BR:ko04812]
|
04147 Exosome [BR:ko04147]
|
02048 Prokaryotic defense system [BR:ko02048]
|
04030 G protein-coupled receptors [BR:ko04030]
|
04050 Cytokine receptors [BR:ko04050]
|
04054 Pattern recognition receptors [BR:ko04054]
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03310 Nuclear receptors [BR:ko03310]
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04040 Ion channels [BR:ko04040]
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04031 GTP-binding proteins [BR:ko04031]
|
04052 Cytokines and neuropeptides [BR:ko04052]
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K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05481 IL1RN, IL1F3; interleukin 1 receptor antagonist
K05488 IL1F10, FKSG75; interleukin 1 family member 10
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05443 IL10, CSIF; interleukin 10
K05417 IL11; interleukin 11
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K22628 IL16; interleukin 16
K05489 IL17A, CTLA8; interleukin 17A
K05490 IL17B, CX1; interleukin 17B
K05491 IL17C, CX2; interleukin 17C
K05492 IL17D, IL27; interleukin 17D
K05493 IL17E, IL25; interleukin 17E
K05494 IL17F, ML1; interleukin 17F
K05482 IL18, IL1F4; interleukin 18
K05444 IL19; interleukin 19
K22667 IL20; interleukin 20
K05434 IL21; interleukin 21
K05445 IL22, IL-TIF; interleukin 22
K05426 IL23A; interleukin 23 subunit alpha
K22668 IL24; interleukin 24
K05446 IL26; interleukin 26
K22629 IL27, IL27A; interleukin 27 subunit alpha
K24476 EBI3, IL27B; interleukin 27 subunit beta
K22631 IL31; interleukin 31
K22632 IL32; interleukin 32
K12967 IL33; interleukin 33
K22633 IL34; interleukin 34
K05484 IL36A, IL1F6; interleukin 36 alpha
K05486 IL36B, IL1F8; interleukin 36 beta
K05487 IL36G, IL1F9; interleukin 36 gamma
K05483 IL36RN, IL1F5; interleukin 36 receptor antagonist protein
K05485 IL37, IL1F7; interleukin 37
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04687 IFNG; interferon gamma
K05442 IFNE; interferon epsilon
K05441 IFNK; interferon kappa
K05447 IFNL1, IL29; interferon lambda 1
K22669 IFNL2_3, IL28; interferon lambda 2/3
K05440 IFNW; interferon omega
K27353 IFNT; interferon tau
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K06854 THPO; thrombopoietin
K05436 TSLP; thymic stromal lymphopoietin
K05418 OSM; oncostatin M
K05419 LIF; leukemia inhibitory factor
K05420 CNTF; ciliary neurotrophic factor
K05421 CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
K05422 CTF1, CT1; cardiotrophin 1
K24382 CTF2; cardiotrophin 2
K05514 CCL1; C-C motif chemokine 1
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K12499 CCL5; C-C motif chemokine 5
K05510 CCL6; C-C motif chemokine 6
K05509 CCL7; C-C motif chemokine 7
K16596 CCL8; C-C motif chemokine 8
K22671 CCL9; C-C motif chemokine 9
K16597 CCL11; C-C motif chemokine 11
K16595 CCL13; C-C motif chemokine 13
K21092 CCL14; C-C motif chemokine 14
K05511 CCL15_23; C-C motif chemokine 15/23
K21093 CCL16; C-C motif chemokine 16
K21083 CCL17; C-C motif chemokine 17
K21094 CCL18; C-C motif chemokine 18
K05512 CCL19, ELC; C-C motif chemokine 19
K14625 CCL20; C-C motif chemokine 20
K16062 CCL21, SLC; C-C motif chemokine 21
K21095 CCL22; C-C motif chemokine 22
K21097 CCL24; C-C motif chemokine 24
K13072 CCL25; C-C motif chemokine 25
K21096 CCL26; C-C motif chemokine 26
K16598 CCL27; C-C motif chemokine 27
K05513 CCL28; C-C motif chemokine 28
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05407 PF4, CXCL4; platelet factor 4
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10029 PPBP, CXCL7; platelet basic protein
K10030 IL8, CXCL8; interleukin 8
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10031 CXCL12; C-X-C motif chemokine 12
K10032 CXCL13; C-X-C motif chemokine 13
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K10034 CXCL15; C-X-C motif chemokine 15
K10035 CXCL16; C-X-C motif chemokine 16
K22627 CXCL17; C-X-C motif chemokine 17
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05507 XCL1, SCM1; C motif chemokine 1
K22675 XCL2, SCM1B; C motif chemokine 2
K24191 PROK; prokineticin
K25387 GPR15L; protein GPR15L
K25418 CYTL1; cytokine-like protein 1
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K05469 TNFSF4, OX40L, CD252; tumor necrosis factor ligand superfamily member 4
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K05470 TNFSF7, CD70; tumor necrosis factor ligand superfamily member 7
K05471 TNFSF8, CD153; tumor necrosis factor ligand superfamily member 8
K05472 TNFSF9, CD137L; tumor necrosis factor ligand superfamily member 9
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05474 TNFSF12, TWEAK; tumor necrosis factor ligand superfamily member 12
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K05478 TNFSF15, VEGI; tumor necrosis factor ligand superfamily member 15
K05479 TNFSF18, GITRL; tumor necrosis factor ligand superfamily member 18
K05480 EDA; ectodysplasin-A
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04384 TGFBN; transforming growth factor beta, invertebrate
K05502 BMP1, TLD; bone morphogenetic protein 1 [EC:3.4.24.19]
K21283 BMP2; bone morphogenetic protein 2
K05496 BMP3; bone morphogenetic protein 3
K04662 BMP4; bone morphogenetic protein 4
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K22670 BMP10; bone morphogenetic protein 10
K05498 BMP15, GDF9B; bone morphogenetic protein 15
K05495 GDF1; growth differentiation factor 1
K05503 GDF2, BMP9; growth differentiation factor 2
K22672 GDF3; growth differentiation factor 3
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K05497 MSTN, GDF8; growth differentiation factor 8
K22673 GDF9; growth differentiation factor 9
K22674 GDF10, BMP3B; growth differentiation factor 10
K22679 GDF11; growth differentiation factor 11
K05504 GDF15; growth differentiation factor 15
K04666 NODAL; nodal
K05500 INHA; inhibin, alpha
K04667 INHBA; inhibin beta A chain
K22687 INHBB; inhibin beta B chain
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04665 AMH; anti-mullerian hormone
K04668 LEFTY; left-right determination factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K05449 VEGFC_D; vascular endothelial growth factor C/D
K16859 PGF; placenta growth factor
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04355 BDNF; brain-derived neurotrophic factor
K05452 GDNF; glial cell derived neurotrophic factor
K25414 NRTN; neurturin
K25415 ARTN; artemin
K25416 PSPN; persephin
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22413 FGF11_12_13, FHF3_1_2; fibroblast growth factor 11/12/13
K23920 FGF14, FHF4; fibroblast growth factor 14
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05460 HGF; hepatocyte growth factor
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K05461 KITLG; KIT ligand
K05462 EFNA; ephrin-A
K05463 EFNB; ephrin-B
K05464 GAS6; growth arrest-specific 6
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K09821 AGT, SERPINA8; angiotensinogen
K03898 KNG, BK; kininogen
K05235 NTS; neurotensin
K05225 APLN; apelin
K05223 NMB; neuromedin B
K05224 GRP; gastrin-releasing peptide
K05226 CCK; cholecystokinin
K16366 EDN1; endothelin-1
K16367 EDN2; endothelin-2
K05227 EDN3; endothelin-3
K05244 GAL; galanin
K25482 GALP; galanin-like peptide
K25694 SPX; spexin
K05254 GHRL; ghrelin
K05265 MLN; motilin
K05249 NMU; neuromedin U
K25690 NMS; neuromedin S
K05247 NPFF; neuropeptide FF-amide peptide
K25692 NPVF; pro-FMRFamide-related neuropeptide VF
K25691 NPS; neuropeptide S
K05232 NPY; neuropeptide Y
K05234 PPY; pancreatic polypeptide
K05233 PYY; peptide YY
K05267 NPB; preproneuropeptide B
K23141 NPW; neuropeptide W
K05228 POMC; proopiomelanocortin
K18832 PENK; proenkephalin A
K15840 PDYN, PENKB; proenkephalin B (prodynorphin)
K25696 PNOC; prepronociceptin
K25693 QRFP; orexigenic neuropeptide QRFP
K05243 OXT; oxytocin-neurophysin 1
K05237 SST; somatostatin
K05238 CORT; cortistatin
K05239 TAC1; tachykinin 1
K05240 TAC3; tachykinin 3
K05241 TAC4; tachykinin 4
K05248 UTS2; urotensin 2
K24267 UTS2B; urotensin-2B
K05242 AVP; arginine vasopressin
K05269 PRH; Prolactin-releasing peptide
K23140 KISS1; metastasis-suppressor KiSS-1
K05246 HCRT; hypocretin (orexin) neuropeptide
K25695 VGF; neurosecretory protein VGF
K19990 CHGA; chromogranin-A
K19991 CHGB; chromogranin-B
K25732 SCG2; secretogranin-2
K25733 SCG3; secretogranin-3
K25734 SCG5; neuroendocrine protein 7B2
K05252 GNRH; gonadotropin-releasing hormone
K05253 TRH; thyrotropin-releasing hormone
K21998 RLN1_2; relaxin 1/2
K22000 RLN3; relaxin 3
K21999 INSL3; insulin-like 3
K22001 INSL5; insulin-like 5
K05229 PMCH; pro-melanin-concentrating hormone
K13768 GAST; gastrin
K12332 CALC; calcitonin
K12333 ADM; adrenomedullin
K25343 ADM2; adrenomedullin-2
K08039 IAPP; islet amyloid polypeptide
K05256 CRH; corticotropin-releasing hormone
K23142 UCN; urcortin
K05257 UCN2_3; urocortin 2/3
K05258 GIP; gastric inhibitory polypeptide
K05259 GCG; glucagon
K05260 GHRH; growth hormone-releasing hormone
K05261 PTH; parathyroid hormone
K23143 PTH2, TIP39; tuberoinfundibular peptide of 39 residues
K05262 ADCYAP; pituitary adenylate cyclase-activating polypeptide
K05263 SCT; secretin
K05264 VIP; vasoactive intestinal peptide
K22608 PTHLH, PTHRP; parathyroid hormone-related hormone
K08522 CGA; glycoprotein hormones alpha chain
K05250 FSHB; follitropin subunit beta
K08521 LHB; lutropin subunit beta
K10045 CGB; chorionic gonadotropin, beta polypeptide
K05251 TSHB; thyrotropin subunit beta
K25483 GPHA2; glycoprotein hormone alpha-2
K25484 GPHB5; glycoprotein hormone beta-5
K12334 NPPA; natriuretic peptide A
K12335 NPPB; natriuretic peptide B
K12336 NPPC; natriuretic peptide C
K16656 NXPH1; neurexophilin-1
K16657 NXPH2; neurexophilin-2
K16658 NXPH3; neurexophilin-3
K25711 NXPH4; neurexophilin-4
K04526 INS; insulin
K05424 LEP; leptin
K05439 PRL; prolactin
K25453 CARTPT; cocaine- and amphetamine-regulated transcript protein
K05231 AGRP; agouti related protein
K08762 DBI, ACBP; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)
K24235 CBLN; cerebellin
K07296 ADIPOQ, ACDC; adiponectin
K03462 NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12]
K13438 RETN; resistin
K20371 NUCB; nucleobindin
K13113 UBL5, HUB1; ubiquitin-like protein 5
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04515 Cell adhesion molecules [BR:ko04515]
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04090 CD molecules [BR:ko04090]
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01504 Antimicrobial resistance genes [BR:ko01504]
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00535 Proteoglycans [BR:ko00535]
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00536 Glycosaminoglycan binding proteins [BR:ko00536]
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K04519 IL1B; interleukin 1 beta
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05431 IL7; interleukin 7
K05443 IL10, CSIF; interleukin 10
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04687 IFNG; interferon gamma
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K12499 CCL5; C-C motif chemokine 5
K16595 CCL13; C-C motif chemokine 13
K05407 PF4, CXCL4; platelet factor 4
K10030 IL8, CXCL8; interleukin 8
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K10031 CXCL12; C-X-C motif chemokine 12
K06495 SELL, CD62L; selectin, lymphocyte
K06496 SELP, CD62P; selectin, platelet
K06461 ITGAM, CD11b; integrin alpha M
K06491 NCAM, CD56; neural cell adhesion molecule
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K16621 BMP7; bone morphogenetic protein 7
K06224 HH; hedgehog
K11988 SHH; sonic hedgehog
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K09782 AREG; amphiregulin
K09783 BTC; betacellulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22413 FGF11_12_13, FHF3_1_2; fibroblast growth factor 11/12/13
K23920 FGF14, FHF4; fibroblast growth factor 14
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K08523 HBEGF; heparin-binding EGF-like growth factor
K05460 HGF; hepatocyte growth factor
K06828 MDK; midkine
K13769 IGF2; insulin-like growth factor 2
K05455 NRG1; neuregulin 1
K16641 HDGF; hepatoma-derived growth factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K16642 PTN; pleiotrophin
K05448 VEGFA; vascular endothelial growth factor A
K25640 MPIG6B; megakaryocyte and platelet inhibitory receptor G6b
K03903 FGA; fibrinogen alpha chain
K03904 FGB; fibrinogen beta chain
K03905 FGG; fibrinogen gamma chain
K05717 FN1; fibronectin 1
K06825 FBN1; fibrillin 1
K23342 FBN2_3; fibrillin 2/3
K06252 TN; tenascin
K24354 SMOC; SPARC-related modular calcium-binding protein
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K06251 VTN; vitronectin
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K19720 COL3A; collagen type III alpha
K06237 COL4A; collagen type IV alpha
K19721 COL5AS; collagen type V/XI/XXIV/XXVII, alpha
K06238 COL6A; collagen type VI alpha
K16617 COL13A; collagen type XIII alpha
K06823 COL18A; collagen type XVIII alpha
K24340 COL19A; collagen type XIX alpha
K24355 COL23A; collagen type XXIII alpha
K24356 COL25A; collagen type XXV alpha
K26586 COLQ; acetylcholinesterase collagenic tail peptide
K05462 EFNA; ephrin-A
K06843 NTN1; netrin 1
K06838 SLIT1; slit 1
K06839 SLIT2; slit 2
K06850 SLIT3; slit 3
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K01314 F10; coagulation factor X [EC:3.4.21.6]
K03913 SERPINA5, PCI; protein C inhibitor
K03911 SERPINC1, AT3; antithrombin III
K03912 SERPIND1, HCF2; heparin cofactor II
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K16643 SERPINE2; glia-derived nexin
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03909 TFPI; tissue factor pathway inhibitor
K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
K07964 HPSE; heparanase [EC:3.2.1.166]
K07965 HPSE2; heparanase 2 [EC:3.2.1.-]
K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
K01059 LPL; lipoprotein lipase [EC:3.1.1.34]
K16627 SOD3; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K19252 VP1; Dependoparvovirus capsid protein VP1/VP2/VP3
K19255 gB; Herpesviridae envelope glycoprotein B
K19256 gC; Simplexvirus envelope glycoprotein C
K19264 gD; Simplexvirus envelope glycoprotein D
K19257 gM, UL10; Herpesviridae envelope glycoprotein M
K22773 gB, UL55; Betaherpesvirinae envelope glycoprotein B
K19287 env, gp160; HIV envelope glycoprotein gp160
K24266 gp120; HIV envelope glycoprotein gp120
K19258 tat; HIV protein Tat
K19259 env; Deltaretrovirus envelope glycoprotein gp62
K24862 gp46; HTLV envelope surface glycoprotein gp46
K19288 p130; Alphavirus structral polyprotein
K19260 L1; Papillomaviridae major capsid protein L1
K19261 F; Pneumoviridae fusion glycoprotein F0
K19262 L5; Mastadenovirus fiber protein
K19263 A27L; Orthopoxvirus protein A27
K13836 CSP; circumsporozoite protein
K15125 fhaB; filamentous hemagglutinin
K16644 actA; actin-assembly inducing protein
K16645 hbhA; heparin binding hemagglutinin HbhA
K16631 ANG, RNASE5; angiogenin [EC:3.1.27.-]
K16646 ANXA5; annexin A5
K09025 APOA5; apolipoprotein A-V
K14462 APOB; apolipoprotein B
K04524 APOE; apolipoprotein E
K04520 APP; amyloid beta A4 protein
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K01319 CTSG; cathepsin G [EC:3.4.21.20]
K05634 PRNP, PrP, CD230; prion protein
K05849 SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
K01242 CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
K06256 CD44; CD44 antigen
K06267 HMMR, RHAMM, CD168; hyaluronan-mediated motility receptor
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K10077 LAYN; layilin
K19012 LYVE1; lymphatic vessel endothelial hyaluronan receptor 1
K19020 STAB1; stabilin-1
K19013 STAB2, HARE; stabilin-2
K19031 CEMIP, KIAA1199; cell migration-inducing and hyaluronan-binding protein [EC:3.2.1.35]
K22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]
K06792 AGC1, CSPG1; aggrecan 1
K06795 BCAN; brevican
K15414 C1QBP; complement component 1 Q subcomponent-binding protein, mitochondrial
K08648 HABP2; hyaluronan binding protein 2 [EC:3.4.21.-]
K06848 HAPLN1, CRTL1; hyaluronan and proteoglycan link protein 1
K06851 HAPLN2; hyaluronan and proteoglycan link protein 2
K06853 HAPLN4; hyaluronan and proteoglycan link protein 4
K18977 HPX; hemopexin
K19014 ITIH1, SHAP; inter-alpha-trypsin inhibitor heavy chain H1
K19015 ITIH2, SHAP; inter-alpha-trypsin inhibitor heavy chain H2
K24513 ITIH3, SHAP; inter-alpha-trypsin inhibitor heavy chain H3
K06794 NCAN, CSPG3; neurocan core protein
K19016 IMPG1, SPACR; interphotoreceptor matrix proteoglycan 1
K19017 IMPG2, SPACRCAN; interphotoreceptor matrix proteoglycan 2
K19018 TNFAIP6, TSG6; tumor necrosis factor-inducible gene 6 protein
K06793 VCAN, CSPG2; versican core protein
K09554 CDC37; cell division cycle protein 37
K19019 HABP4; intracellular hyaluronan-binding protein 4
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00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
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04091 Lectins [BR:ko04091]
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04990 Domain-containing proteins not elsewhere classified [BR:ko04990]
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO)