K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06751 MHC1; MHC class I antigen
K24231 KIR2DL4, CD158D; killer cell immunoglobulin-like receptor 2DL4
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K02833 HRAS; GTPase HRas
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K06627 CCNA; cyclin-A
K21769 MYBL2, B-MYB; myb-related protein B
K21773 LIN9; protein lin-9
K21774 LIN37; protein lin-37
K21775 LIN52; protein lin-52
K21776 LIN54; protein lin-54
K10752 RBBP4, HAT2, CAF1, MIS16; histone-binding protein RBBP4
K09406 FOXM; forkhead box protein M
K04377 MYC; Myc proto-oncogene protein
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1, pnt; C-ets-1
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN, NBS1; nibrin
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K02830 HRAD1, RAD17; cell cycle checkpoint protein [EC:3.1.11.2]
K10903 HUS1; HUS1 checkpoint protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K14381 SQSTM1; sequestosome 1
K09183 GATA4; GATA-binding protein 4
K21124 TRAF3IP2, ACT1; adaptor protein CIKS
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04383 IL1A; interleukin 1 alpha
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K18753 ZFP36L; butyrate response factor
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K04982 TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
|
K00567 ogt, MGMT; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
K10860 ALKBH3, DEPC1; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
K01669 phr, PHR1; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
K03648 UNG, UDG; uracil-DNA glycosylase [EC:3.2.2.27]
K10861 UDG2, CCNO; uracil-DNA glycosylase 2 [EC:3.2.2.-]
K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
K10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]
K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]
K10773 NTHL1, nth; endonuclease III [EC:3.2.2.- 4.2.99.18]
K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K04802 PCNA; proliferating cell nuclear antigen
K04799 FEN1, RAD2; flap endonuclease-1 [EC:3.1.-.-]
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K10803 XRCC1; DNA-repair protein XRCC1
K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
K08075 E3.1.3.32; polynucleotide 3'-phosphatase [EC:3.1.3.32]
K10802 HMGB1; high mobility group protein B1
K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10838 XPC; xeroderma pigmentosum group C-complementing protein
K10839 RAD23, HR23; UV excision repair protein RAD23
K10840 CETN2; centrin-2
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K10609 CUL4; cullin 4
K10610 DDB1; DNA damage-binding protein 1
K10140 DDB2; DNA damage-binding protein 2
K15082 RAD7; DNA repair protein RAD7
K15083 RAD16; DNA repair protein RAD16
K03006 RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
K03010 RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
K03011 RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3
K03012 RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
K03013 RPABC1, RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
K03014 RPABC2, RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
K03015 RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
K03016 RPABC3, RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
K03017 RPB9, POLR2I; DNA-directed RNA polymerase II subunit RPB9
K03007 RPABC5, RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
K03008 RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11
K03009 RPABC4, RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
K10570 ERCC8, CKN1, CSA; DNA excision repair protein ERCC-8
K10841 ERCC6, CSB, RAD26; DNA excision repair protein ERCC-6
K23720 UVSSA; UV-stimulated scaffold protein A
K25829 ELOF1, ELF1; transcription elongation factor 1
K10843 ERCC3, XPB; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
K10844 ERCC2, XPD; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
K03141 TFIIH1, GTF2H1, TFB1; transcription initiation factor TFIIH subunit 1
K03142 TFIIH2, GTF2H2, SSL1; transcription initiation factor TFIIH subunit 2
K03143 TFIIH3, GTF2H3, TFB4; transcription initiation factor TFIIH subunit 3
K03144 TFIIH4, GTF2H4, TFB2; transcription initiation factor TFIIH subunit 4
K10845 TTDA, GTF2H5, TFB5; TFIIH basal transcription factor complex TTD-A subunit
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K06634 CCNH; cyclin H
K10842 MNAT1; CDK-activating kinase assembly factor MAT1
K07466 RFA1, RPA1, rpa; replication factor A1
K10739 RFA2, RPA2; replication factor A2
K10740 RPA3; replication factor A3
K10741 RPA4; replication factor A4
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K10848 ERCC4, XPF; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K10846 ERCC5, XPG, RAD2; DNA excision repair protein ERCC-5
K15075 MET18, MMS19; DNA repair/transcription protein MET18/MMS19
K03869 CUL3; cullin 3
K10612 CUL5; cullin 5
K03872 ELOC, TCEB1; elongin-C
K03873 ELOB, TCEB2; elongin-B
K15076 ELOA, TCEB3; elongin-A
K15077 ELA1; elongin-A
K26545 UBAP2; ubiquitin-associated protein 2
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K10864 PMS1; DNA mismatch repair protein PMS1
K08734 MLH1; DNA mismatch repair protein MLH1
K10858 PMS2; DNA mismatch repair protein PMS2
K08739 MLH3; DNA mismatch repair protein MLH3
K10754 RFC1; replication factor C subunit 1
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
K24755 WDR76, CMR1; WD repeat-containing protein 76
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN, NBS1; nibrin
K10868 XRS2; DNA repair protein XRS2
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K10683 BARD1; BRCA1-associated RING domain protein 1
K20774 FAM175A, ABRA1; BRCA1-A complex subunit Abraxas
K20775 UIMC1, RAP80; BRCA1-A complex subunit RAP80
K20776 BABAM, NBA1, MERIT40; BRISC and BRCA1-A complex member 1
K12173 BRE, BRCC45; BRCA1-A complex subunit BRE
K11864 BRCC3, BRCC36; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
K15362 BRIP1, BACH1, FANCJ; fanconi anemia group J protein [EC:5.6.2.3]
K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
K20773 RBBP8, CTIP; DNA endonuclease RBBP8 [EC:3.1.-.-]
K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
K10897 PALB2, FANCN; partner and localizer of BRCA2
K04482 RAD51; DNA repair protein RAD51
K10869 RAD51L1, RAD51B; RAD51-like protein 1
K10870 RAD51L2, RAD51C; RAD51-like protein 2
K10871 RAD51L3, RAD51D; RAD51-like protein 3
K10879 XRCC2; DNA-repair protein XRCC2
K10880 XRCC3; DNA-repair protein XRCC3
K10957 RAD55; DNA repair protein RAD55
K10958 RAD57; DNA repair protein RAD57
K10873 RAD52; DNA repair and recombination protein RAD52
K10874 RDM1, RAD52B; RAD52 motif-containing protein 1
K26556 RAD52-1; DNA repair RAD52-like protein 1, mitochondrial
K26558 RAD52-2; DNA repair RAD52-like protein 2, chloroplastic
K10959 RAD59; DNA repair protein RAD59
K10875 RAD54L, RAD54; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
K10900 WRN, RECQL2; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
K10901 BLM, RECQL3, SGS1; bloom syndrome protein [EC:5.6.2.4]
K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K10990 RMI1, BRAP75; RecQ-mediated genome instability protein 1
K15364 NCE4, RMI1; RecQ-mediated genome instability protein 1
K15365 RMI2; RecQ-mediated genome instability protein 2
K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
K17491 SMEK, PPP4R3; protein phosphatase 4 regulatory subunit 3
K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
K19022 AP5B1; AP-5 complex subunit beta-1
K19023 AP5M1, MUDENG; AP-5 complex subunit mu-1
K19024 AP5S1; AP-5 complex subunit sigma-1
K19025 AP5Z1, SPG48; AP-5 complex subunit zeta-1
K22803 SMC5; structural maintenance of chromosomes protein 5
K22804 SMC6; structural maintenance of chromosomes protein 6
K22805 FAM84A, NSE1; protein FAM84A
K22817 NSMCE1, NSE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
K22756 NSMCE2, NSE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
K22823 NSMCE3, NSE3; non-structural maintenance of chromosomes element 3
K22825 NSMCE4, NSE4; non-structural maintenance of chromosomes element 4
K22826 EID3, NSMCE4B; EP300-interacting inhibitor of differentiation 3
K26126 SLF1; SMC5-SMC6 complex localization factor protein 1
K26127 SLF2; SMC5-SMC6 complex localization factor protein 2
K10882 EME1, MMS4; crossover junction endonuclease EME1 [EC:3.1.22.-]
K10883 EME2; crossover junction endonuclease EME2
K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K10991 SWI5, SAE3; DNA repair protein Swi5/Sae3
K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
K10484 BTBD12, SLX4; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
K15079 SLX4; structure-specific endonuclease subunit SLX4
K15338 GEN1, YEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
K19026 SPG11; spatacsin
K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
K20778 RAD51AP1; RAD51-associated protein 1
K11339 MORF4L1, MRG15, EAF3; mortality factor 4-like protein 1
K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
K22806 SPIDR; DNA repair-scaffolding protein
K22810 FAM84B; protein FAM84B
K23112 BRAT1; BRCA1-associated ATM activator 1
K23456 CFAP410, C21ORF2; cilla- and flagella-associated protein
K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
K25770 ZSWIM7, SWS1; zinc finger SWIM domain-containing protein 7
K25771 SWSAP1; ATPase SWSAP1
K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
K25791 HSF2BP; heat shock factor 2-binding protein
K26125 MMS22L; protein MMS22-like
K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
K27412 PARPBP; PCNA-interacting partner
K22807 WRNexo; werner syndrome-like exonuclease [EC:3.1.11.-]
K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
K26559 WHY1; single-stranded DNA-binding protein WHY1
K26561 WHY2; single-stranded DNA-binding protein WHY2
K26560 WHY3; single-stranded DNA-binding protein WHY3
K14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
K15080 SAW1; single-strand annealing weakened protein 1
K26124 RTT101, CUL8; cullin 8
K26122 MMS22; E3 ubiquitin-protein ligase substrate receptor MMS22
K26123 MMS1; E3 ubiquitin-protein ligase linker protein MMS1
K10884 XRCC6, KU70, G22P1; ATP-dependent DNA helicase 2 subunit 1
K10885 XRCC5, KU80, G22P2; ATP-dependent DNA helicase 2 subunit 2
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K10777 LIG4, DNL4; DNA ligase 4 [EC:6.5.1.1]
K10886 XRCC4; DNA-repair protein XRCC4
K10980 NHEJ1, XLF; non-homologous end-joining factor 1
K10982 LIF1; ligase-interacting factor 1
K10983 NEJ1, LIF2; non-homologous end-joining protein 1
K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
K10887 DCLRE1C, ARTEMIS, SCIDA; DNA cross-link repair 1C protein [EC:3.1.-.-]
K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
K23386 PWWP3, MUM1; PWWP domain-containing DNA repair factor 3
K25772 PAXX; protein PAXX
K26155 CYREN, MRI; cell cycle regulator of non-homologous end joining
K25792 JMJD8; jumonji domain-containing protein 8
K26128 SHLD1; shieldin complex subunit 1
K26129 SHLD2; shieldin complex subunit 2
K26130 SHLD3; shieldin complex subunit 3
K10888 FANCA; fanconi anemia group A protein
K10889 FANCB; fanconi anemia group B protein
K10890 FANCC; fanconi anemia group C protein
K10892 FANCE; fanconi anemia group E protein
K10893 FANCF; fanconi anemia group F protein
K10894 FANCG; fanconi anemia group G protein
K10606 FANCL, PHF9; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
K10896 FANCM; fanconi anemia group M protein
K10898 FAAP24; fanconi anemia-associated protein
K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
K06054 HES1; hairy and enhancer of split 1
K11511 APITD1, CENPS, MHF1; centromere protein S
K15360 STRA13, CENPX, MHF2; centromere protein X
K13960 UBE2T, HSPC150; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
K10891 FANCD2; fanconi anemia group D2 protein
K10895 FANCI; fanconi anemia group I protein
K15363 FAN1, MTMR15; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
K11137 TELO2, TEL2; telomere length regulation protein
K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
K15361 WDR48, UAF1; WD repeat-containing protein 48
K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
K15499 PPP6R1, SAPS1; serine/threonine-protein phosphatase 6 regulatory subunit 1
K15500 PPP6R2, SAPS2; serine/threonine-protein phosphatase 6 regulatory subunit 2
K15501 PPP6R3, SAPS3; serine/threonine-protein phosphatase 6 regulatory subunit 3
K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
K23314 WRAP53, TCAB1; telomerase Cajal body protein 1
K24164 TPRN; taperin
K24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1
K24752 WDR70; WD repeat-containing protein 70
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
K02350 REV3L, POLZ; DNA polymerase zeta [EC:2.7.7.7]
K03508 POLZ2, rev7; DNA polymerase zeta [EC:2.7.7.7]
K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
K10573 UBE2A, UBC2, RAD6A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
K10574 UBE2B, RAD6B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
K15711 SMARCA3, HLTF; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10580 UBE2N, BLU, UBC13; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K24051 SPRTN; SprT-like domain-contaning protein Spartan
K26957 GCNA, ACRC; germ cell nuclear acidic protein
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K10903 HUS1; HUS1 checkpoint protein
K10996 HUS1B; checkpoint protein HUS1B
K02830 HRAD1, RAD17; cell cycle checkpoint protein [EC:3.1.11.2]
K06662 HRAD17, RAD24; cell cycle checkpoint protein
K02544 MEC3; G2-specific checkpoint protein
K06663 DDC1; DNA damage checkpoint protein
K10997 TIMELESS, TOF1, SWI1; replication fork protection complex subunit TIMELESS/Tof1/Swi1
K10998 TIPIN, CSM3, SWI3; replication fork protection complex subunit TIPIN/Csm3/Swi3
K25773 CLSPN; claspin
K11272 MRC1; mediator of replication checkpoint protein 1
K20403 TTI1; TELO2-interacting protein 1
K23115 TTI2; TELO2-interacting protein 2
K23390 BAG6; large proline-rich protein BAG6
K23388 UBL4; ubiquitin-like protein 4
K23387 GET4; golgi to ER traffic protein 4
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K10905 ATRIP; ATR interacting protein
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06630 YWHAE; 14-3-3 protein epsilon
K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K02831 RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
K21944 PER1; period circadian protein 1
K02633 PER2; period circadian protein 2
K21945 PER3; period circadian protein 3
K06661 RAD9; DNA repair protein RAD9
K20780 MDC1; mediator of DNA damage checkpoint protein 1
K02543 MEC1; cell cycle checkpoint protein MEC1
K15081 AMN1; antagonist of mitotic exit network protein 1
K17336 PLS3; plastin-3
K18340 AEN, ISG20L1; apoptosis-enhancing nuclease [EC:3.1.-.-]
K08862 PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
K19596 PLK5; inactive serine/threonine-protein kinase PLK5
K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
K24663 NDD1; nuclear division defective protein 1
K24664 FKH; forkhead protein FKH
K22422 DONSON; protein downstream neighbor of Son
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K23389 KLLN; killin
K24458 SLFN11; schlafen family member 11 [EC:3.6.-.-]
K24782 CHMP4C, SNF7, VPS32C; charged multivesicular body protein 4C
K12196 VPS4; vacuolar protein-sorting-associated protein 4
K24778 ZFYVE19, ANCHR; abscission/NoCut checkpoint regulator
K25059 SDE2; replication stress response regulator SDE2
K24770 DSE1, ALT2, EMB2757; protein decreased size exclusion limit 1
K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
K02331 POL5, MYBBP1A; DNA polymerase phi [EC:2.7.7.7]
K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
K10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]
K15340 DCLRE1A, SNM1A, PSO2; DNA cross-link repair 1A protein
K15341 DCLRE1B, SNM1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
K17815 EXO5; exonuclease V [EC:3.1.-.-]
K21813 ENDOV; endonuclease V [EC:3.1.26.-]
K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
K21411 ANKLE1, LEM3; ankyrin repeat and LEM domain-containing protein 1
K05986 NUCS; nuclease S1 [EC:3.1.30.1]
K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
K10599 PRPF19, PRP19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
K12860 CDC5L, CDC5, CEF1; pre-mRNA-splicing factor CDC5/CEF1
K12861 BCAS2; pre-mRNA-splicing factor SPF27
K12862 PLRG1, PRL1, PRP46; pleiotropic regulator 1
K03574 mutT, NUDT15, MTH2; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
K17816 NUDT1, MTH1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
K17817 NUDT18, MTH3; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
K01520 dut, DUT; dUTP diphosphatase [EC:3.6.1.23]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
K13530 adaA; AraC family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]
K13531 adaB; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
K10563 mutM, fpg; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
K01142 E3.1.11.2, xthA; exodeoxyribonuclease III [EC:3.1.11.2]
K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
K05982 E3.1.21.7, nfi; deoxyribonuclease V [EC:3.1.21.7]
K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
K01972 E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
K02335 polA; DNA polymerase I [EC:2.7.7.7]
K03701 uvrA; excinuclease ABC subunit A
K03702 uvrB; excinuclease ABC subunit B
K03703 uvrC; excinuclease ABC subunit C
K05984 cho; excinuclease Cho [EC:3.1.25.-]
K03657 uvrD, pcrA; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
K13797 rpoBC; DNA-directed RNA polymerase subunit beta-beta' [EC:2.7.7.6]
K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
K03048 rpoE; DNA-directed RNA polymerase subunit delta
K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
K03555 mutS; DNA mismatch repair protein MutS
K07456 mutS2; DNA mismatch repair protein MutS2
K03572 mutL; DNA mismatch repair protein MutL
K03573 mutH; DNA mismatch repair protein MutH
K01141 sbcB, exoI; exodeoxyribonuclease I [EC:3.1.11.1]
K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
K14159 rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
K03111 ssb; single-strand DNA-binding protein
K06223 dam; DNA adenine methylase [EC:2.1.1.72]
K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
K03553 recA; recombination protein RecA
K03550 ruvA; holliday junction DNA helicase RuvA
K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
K02686 priB; primosomal replication protein N
K04067 priC; primosomal replication protein N''
K02317 dnaT; DNA replication protein DnaT
K03546 sbcC, rad50; DNA repair protein SbcC/Rad50
K03547 sbcD, mre11; DNA repair protein SbcD/Mre11
K04485 radA, sms; DNA repair protein RadA/Sms
K03629 recF; DNA replication and repair protein RecF
K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
K03584 recO; DNA repair protein RecO (recombination protein O)
K06187 recR; recombination protein RecR
K03631 recN; DNA repair protein RecN (Recombination protein N)
K03700 recU; recombination protein U
K03554 rdgC; recombination associated protein RdgC
K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
K15342 cas1; CRISP-associated protein Cas1
K19789 radD; DNA repair protein RadD
K04483 radA; DNA repair protein RadA
K04484 radB; DNA repair protein RadB
K03552 hjr, hjc, hje; holliday junction resolvase [EC:3.1.21.10]
K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-]
K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
K10979 ku; DNA end-binding protein Ku
K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
K05787 hupA; DNA-binding protein HU-alpha
K03530 hupB; DNA-binding protein HU-beta
K10906 recE; exodeoxyribonuclease VIII [EC:3.1.11.-]
K07455 recT; recombination protein RecT
K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
K04764 ihfA, himA; integration host factor subunit alpha
K05788 ihfB, himD; integration host factor subunit beta
K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
K03746 hns; DNA-binding protein H-NS
K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
K03502 umuC; DNA polymerase V
K03503 umuD; DNA polymerase V [EC:3.4.21.-]
K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
K01356 lexA; repressor LexA [EC:3.4.21.88]
K02336 polB; DNA polymerase II [EC:2.7.7.7]
K14160 imuA; protein ImuA
K14161 imuB; protein ImuB
K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
K14623 dinD; DNA-damage-inducible protein D
K12149 dinI; DNA-damage-inducible protein I
K03565 recX; regulatory protein
K01157 rpnA; recombination-promoting nuclease RpnA [EC:3.1.21.-]
K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
K24088 rpnC; recombination-promoting nuclease RpnC [EC:3.1.21.-]
K24089 rpnD; recombination-promoting nuclease RpnD [EC:3.1.21.-]
K24090 rpnE; recombination-promoting nuclease RpnE
K02347 polX, dpx; DNA polymerase (family X)
K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
K03658 helD; DNA helicase IV [EC:5.6.2.4]
K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:3.6.4.13 5.6.2.4]
K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
K00525 E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
K00526 E1.17.4.1B, nrdB, nrdF; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
K22585 nreA; DNA repair protein NreA
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