KEGG Orthology (KO)

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 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:ko00061]
     00062 Fatty acid elongation [PATH:ko00062]
     00071 Fatty acid degradation [PATH:ko00071]
     00072 Synthesis and degradation of ketone bodies [PATH:ko00072]
     00073 Cutin, suberine and wax biosynthesis [PATH:ko00073]
     00100 Steroid biosynthesis [PATH:ko00100]
     00120 Primary bile acid biosynthesis [PATH:ko00120]
       K07440  CYP46A1; cholesterol 24-hydroxylase [EC:1.14.14.25]
       K07439  CYP39A1; 24-hydroxycholesterol 7alpha-hydroxylase [EC:1.14.14.26]
       K12408  HSD3B7; cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase [EC:1.1.1.181]
       K10223  CH25H; cholesterol 25-hydroxylase [EC:1.14.99.38]
       K07430  CYP7B; 25/26-hydroxycholesterol 7alpha-hydroxylase [EC:1.14.14.29]
       K00489  CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
       K00488  CYP27A1; cholestanetriol 26-monooxygenase [EC:1.14.15.15]
       K07431  CYP8B1; sterol 12-alpha-hydroxylase [EC:1.14.18.8 1.14.14.139]
       K00251  AKR1D1; 3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]
       K00037  AKR1C4; 3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
       K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
       K01796  E5.1.99.4, AMACR, mcr; alpha-methylacyl-CoA racemase [EC:5.1.99.4]
       K10214  ACOX2; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:1.17.99.3]
       K12405  HSD17B4; (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.- 4.2.1.107 4.2.1.119]
       K08764  SCP2, SCPX; sterol carrier protein 2 [EC:2.3.1.176]
       K11992  ACOT8, PTE; acyl-CoA thioesterase 8 [EC:3.1.2.27]
       K00659  BAAT; bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
       K01442  E3.5.1.24; choloylglycine hydrolase [EC:3.5.1.24]
     00121 Secondary bile acid biosynthesis [PATH:ko00121]
     00140 Steroid hormone biosynthesis [PATH:ko00140]
     00561 Glycerolipid metabolism [PATH:ko00561]
     00564 Glycerophospholipid metabolism [PATH:ko00564]
     00565 Ether lipid metabolism [PATH:ko00565]
     00600 Sphingolipid metabolism [PATH:ko00600]
     00590 Arachidonic acid metabolism [PATH:ko00590]
     00591 Linoleic acid metabolism [PATH:ko00591]
     00592 alpha-Linolenic acid metabolism [PATH:ko00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:ko01040]
       K10247  ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199]
       K10205  ELOVL2; elongation of very long chain fatty acids protein 2 [EC:2.3.1.199]
       K10248  ELOVL3; elongation of very long chain fatty acids protein 3 [EC:2.3.1.199]
       K10249  ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
       K10244  ELOVL5; elongation of very long chain fatty acids protein 5 [EC:2.3.1.199]
       K10203  ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]
       K10250  ELOVL7; elongation of very long chain fatty acids protein 7 [EC:2.3.1.199]
       K10245  ELO2; fatty acid elongase 2 [EC:2.3.1.199]
       K10246  ELO3; fatty acid elongase 3 [EC:2.3.1.199]
       K10251  HSD17B12, KAR, IFA38; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
       K10703  HACD, PHS1, PAS2; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
       K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
       K00507  SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
       K03921  FAB2, SSI2, desA1; acyl-[acyl-carrier-protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]
       K03922  desA2; acyl-[acyl-carrier-protein] desaturase [EC:1.14.19.2]
       K22769  desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-]
       K22770  K22770; stearoyl-CoA 9-desaturase NADPH oxidoreductase
       K10256  FAD2; omega-6 fatty acid desaturase / acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:1.14.19.6 1.14.19.22]
       K23006  FAD3; omega-3 fatty acid desaturase (Delta-15 desaturase) [EC:1.14.19.-]
       K22993  K22993; bifunctional Delta-12/omega-3 fatty acid desaturase [EC:1.14.19.6 1.14.19.-]
       K10226  FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
       K10224  FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44]
       K00232  E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6]
       K12405  HSD17B4; (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.- 4.2.1.107 4.2.1.119]
       K07513  ACAA1; acetyl-CoA acyltransferase 1 [EC:2.3.1.16]
       K08764  SCP2, SCPX; sterol carrier protein 2 [EC:2.3.1.176]
       K01068  ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
       K17360  ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2]
       K00659  BAAT; bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
       K10804  tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]
       K10805  tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
       K10806  yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-]
 
   09104 Nucleotide metabolism
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
     04144 Endocytosis [PATH:ko04144]
     04145 Phagosome [PATH:ko04145]
     04142 Lysosome [PATH:ko04142]
     04146 Peroxisome [PATH:ko04146]
       K13335  PEX16; peroxin-16
       K13336  PEX3; peroxin-3
       K13337  PEX19; peroxin-19
       K05677  ABCD3, PMP70; ATP-binding cassette, subfamily D (ALD), member 3
       K13338  PEX1; peroxin-1
       K13339  PEX6, PXAAA1; peroxin-6
       K13340  PEX26; peroxin-26
       K13341  PEX7, PTS2R; peroxin-7
       K13342  PEX5, PXR1; peroxin-5
       K13343  PEX14; peroxin-14
       K13344  PEX13; peroxin-13
       K13345  PEX12, PAF3; peroxin-12
       K13346  PEX10; peroxin-10
       K06664  PEX2, PXMP3; peroxin-2
       K13347  PXMP2, PMP22; peroxisomal membrane protein 2
       K13348  MPV17; protein Mpv17
       K13349  MPV17L; Mpv17-like protein
       K13350  PXMP4, PMP24; peroxisomal membrane protein 4
       K13351  PEX11A; peroxin-11A
       K13352  PEX11B; peroxin-11B
       K13353  PEX11C; peroxin-11C
       K13354  SLC25A17, PMP34; solute carrier family 25 (peroxisomal adenine nucleotide transporter), member 17
       K12261  HACL1; 2-hydroxyacyl-CoA lyase 1 [EC:4.1.-.-]
       K01796  E5.1.99.4, AMACR, mcr; alpha-methylacyl-CoA racemase [EC:5.1.99.4]
       K00477  PHYH; phytanoyl-CoA hydroxylase [EC:1.14.11.18]
       K00232  E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6]
       K10214  ACOX2; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:1.17.99.3]
       K12405  HSD17B4; (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.- 4.2.1.107 4.2.1.119]
       K08764  SCP2, SCPX; sterol carrier protein 2 [EC:2.3.1.176]
       K00659  BAAT; bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
       K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
       K07513  ACAA1; acetyl-CoA acyltransferase 1 [EC:2.3.1.16]
       K13237  DECR2; peroxisomal 2,4-dienoyl-CoA reductase [EC:1.3.1.34]
       K12663  ECH1; Delta3,5-Delta2,4-dienoyl-CoA isomerase [EC:5.3.3.21]
       K05675  ABCD1, ALD; ATP-binding cassette, subfamily D (ALD), member 1
       K05676  ABCD2, ALDL1; ATP-binding cassette, subfamily D (ALD), member 2
       K05678  ABCD4, PXMP1L; ATP-binding cassette, subfamily D (ALD), member 4
       K15628  PXA; ATP-binding cassette, subfamily D (ALD), peroxisomal long-chain fatty acid import protein
       K08746  SLC27A2, FACVL1, FATP2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
       K01897  ACSL, fadD; long-chain acyl-CoA synthetase [EC:6.2.1.3]
       K07753  PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38]
       K13239  ECI2, PECI; Delta3-Delta2-enoyl-CoA isomerase [EC:5.3.3.8]
       K22587  DCI1; Delta3,5-Delta2,4-dienoyl-CoA isomerase [EC:5.3.3.21]
       K17879  NUDT7; peroxisomal coenzyme A diphosphatase NUDT7 [EC:3.6.1.-]
       K03426  E3.6.1.22, NUDT12, nudC; NAD+ diphosphatase [EC:3.6.1.22]
       K13355  NUDT19; nucleoside diphosphate-linked moiety X motif 19, mitochondrial [EC:3.6.1.-]
       K11992  ACOT8, PTE; acyl-CoA thioesterase 8 [EC:3.1.2.27]
       K00624  E2.3.1.7; carnitine O-acetyltransferase [EC:2.3.1.7]
       K05940  CROT; carnitine O-octanoyltransferase [EC:2.3.1.137]
       K01578  MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
       K00649  GNPAT; glyceronephosphate O-acyltransferase [EC:2.3.1.42]
       K00803  AGPS, agpS; alkyldihydroxyacetonephosphate synthase [EC:2.5.1.26]
       K13356  FAR; alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]
       K00869  E2.7.1.36, MVK, mvaK1; mevalonate kinase [EC:2.7.1.36]
       K13273  PMVK; phosphomevalonate kinase [EC:2.7.4.2]
       K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
       K00273  DAO, aao; D-amino-acid oxidase [EC:1.4.3.3]
       K00272  DDO; D-aspartate oxidase [EC:1.4.3.1]
       K00031  IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42]
       K00308  PAOX; N1-acetylpolyamine oxidase [EC:1.5.3.13]
       K00306  PIPOX; sarcosine oxidase / L-pipecolate oxidase [EC:1.5.3.1 1.5.3.7]
       K01640  E4.1.3.4, HMGCL, hmgL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
       K11517  HAO; (S)-2-hydroxy-acid oxidase [EC:1.1.3.15]
       K03781  katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
       K11187  PRDX5; peroxiredoxin 5, atypical 2-Cys peroxiredoxin [EC:1.11.1.15]
       K04565  SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
       K04564  SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K13279  PRDX1; peroxiredoxin 1 [EC:1.11.1.15]
       K08726  EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
       K13299  GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
       K00106  XDH; xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
       K11147  DHRS4; dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-]
     04140 Autophagy - animal [PATH:ko04140]
     04138 Autophagy - yeast [PATH:ko04138]
     04136 Autophagy - other [PATH:ko04136]
     04137 Mitophagy - animal [PATH:ko04137]
     04139 Mitophagy - yeast [PATH:ko04139]
 
   09143 Cell growth and death
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

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Last updated: July 23, 2019