KEGG Orthology (KO)

[ Brite menu | Download htext | Download json | Help ]
Search

1st Level  2nd Level  3rd Level  4th Level 

 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system [PATH:ko02020]
     04010 MAPK signaling pathway [PATH:ko04010]
     04013 MAPK signaling pathway - fly [PATH:ko04013]
       K12377  TSL; torso-like protein
       K20226  TRK; protein trunk
       K20227  FS1M3; female sterile (1) M3, polehole
       K20228  FS1N; female sterile (1) Nasrat
       K12378  TOR; tyrosine-protein kinase receptor torso [EC:2.7.10.1]
       K02104  AOS; protein giant-lens (argos)
       K16690  VN; protein vein
       K20229  SPI; protein spitz
       K02447  GRK; protein gruken
       K16691  KRN; keren
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K20230  KEK1; kekkon-1
       K04623  BOSS; bride of sevenless protein
       K05088  ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]
       K06279  SHC1; SHC-transforming protein 1
       K04364  GRB2; growth factor receptor-bound protein 2
       K20231  DOS; protein daughter of sevenless
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K03099  SOS; son of sevenless
       K17383  SPRY2; protein sprouty homolog 2
       K07827  KRAS, KRAS2; GTPase KRas
       K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
       K12380  RASA3; Ras GTPase-activating protein 3
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K17536  CNKSR2, CNK2, KSR2; connector enhancer of kinase suppressor of Ras 2
       K18529  KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K20220  PTP-ER; tyrosine-protein phosphatase ERK [EC:3.1.3.48]
       K20223  IPO7, RANBP7; importin-7
       K20225  CIC; capicua transcriptional repressor
       K08545  NR2E1, TLX, tll; nuclear receptor subfamily 2 group E member 1
       K04497  GROUCHO; groucho
       K12379  HKB; huckebein
       K02678  ETS1, pnt; C-ets-1
       K03211  ETV6_7, yan; ETS translocation variant 6/7
       K20232  EDL; ETS-domain lacking
       K14290  XPO1, CRM1; exportin-1
       K09237  TTK; tramtrack
       K20233  PHYL; phyllopod
       K04506  SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
       K04508  TBL1; transducin (beta)-like 1
       K06689  UBE2D, UBC4, UBC5; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
       K20214  LZ; RUNX transcription factor Lozenge
       K20211  PROX1; prospero homeobox 1
       K16678  EGR; eiger
       K16679  WGN; wengen
       K20234  DOK2; docking protein 2
       K08892  FRK, PTK5; fyn-related kinase [EC:2.7.10.2]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K07364  TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
       K17512  SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]
       K08840  TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K08601  CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04417  MAP3K9, MLK1; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04461  PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K17608  STRN1_3_4; striatin 1/3/4
       K04448  JUN; transcription factor AP-1
       K09031  FOSLN; fos-like antigen, invertebrate
       K20210  RREB1; ras-responsive element-binding protein 1
       K20235  RAW; raw
       K04662  BMP4; bone morphogenetic protein 4
       K05759  PFN; profilin
       K20216  DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
       K20016  HID; cell death protein hid
       K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
       K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K13411  DUOX, THOX; dual oxidase [EC:1.6.3.1 1.11.1.-]
       K10176  TBX2; T-box protein 2
       K09260  MEF2A; MADS-box transcription enhancer factor 2A
       K04564  SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
     04016 MAPK signaling pathway - plant [PATH:ko04016]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04341 Hedgehog signaling pathway - fly [PATH:ko04341]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway - fly [PATH:ko04391]
       K16673  LIX1L; LIX1-like protein
       K16674  FJX1; four-jointed box protein 1
       K16507  DCHS1_2, PCDH16_23; protocadherin-16/23
       K16669  FAT4; protocadherin Fat 4
       K08960  CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
       K05628  RERE; arginine-glutamic acid dipeptide repeats protein
       K16675  ZDHHC9_14_18; palmitoyltransferase ZDHHC9/14/18 [EC:2.3.1.225]
       K16676  LPP; lipoma-prefererred partner
       K16677  DACHS; dachs
       K06094  LLGL; lethal(2) giant larvae protein
       K06069  PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
       K09851  RASSF2_4; Ras association domain-containing protein 2/4
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K10149  TP63; tumor protein p63
       K16678  EGR; eiger
       K16679  WGN; wengen
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K16680  ED; echinoid
       K05692  ACTB_G1; actin beta/gamma 1
       K16681  CRB; protein crumbs
       K04237  PARD3; partitioning defective protein 3
       K06093  PARD6; partitioning defective protein 6
       K06091  MPP5, PALS1; MAGUK p55 subfamily member 5
       K06095  MPDZ, MUPP1, Patj; multiple PDZ domain protein
       K16682  AJUBA, LIMD1, WTIP; LIM domain-containing protein
       K16175  SCRIB; protein scribble
       K12076  DLG1; disks large protein 1
       K24050  DLG5; discs large protein 5
       K16683  EX; protein expanded
       K16684  NF2; merlin
       K16685  WWC1; protein KIBRA
       K04412  STK3, MST2; serine/threonine kinase 3
       K16686  SAV1, Sav; scaffold protein salvador
       K08791  LATS1_2, Wts; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
       K06685  MOB1, Mats; MOB kinase activator 1
       K16687  YAP1, Yki; transcriptional coactivator YAP1
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K04676  SMAD1; mothers against decapentaplegic homolog 1
       K09448  TEAD; transcriptional enhancer factor
       K16672  HTH; homeobox protein homothorax
       K09236  TSHZ; teashirt
       K16736  BAN; bantam
       K16688  DIA; diaphanous
       K06626  CCNE; G1/S-specific cyclin-E1
       K04377  MYC; Myc proto-oncogene protein
       K02306  DALLY; dally
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K16689  UPD; unpaired
       K16690  VN; protein vein
       K16691  KRN; keren
     04392 Hippo signaling pathway - multiple species [PATH:ko04392]
     04370 VEGF signaling pathway [PATH:ko04370]
     04371 Apelin signaling pathway [PATH:ko04371]
     04630 JAK-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04072 Phospholipase D signaling pathway [PATH:ko04072]
     04071 Sphingolipid signaling pathway [PATH:ko04071]
     04024 cAMP signaling pathway [PATH:ko04024]
     04022 cGMP-PKG signaling pathway [PATH:ko04022]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
     04152 AMPK signaling pathway [PATH:ko04152]
     04150 mTOR signaling pathway [PATH:ko04150]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:ko04110]
     04111 Cell cycle - yeast [PATH:ko04111]
     04112 Cell cycle - Caulobacter [PATH:ko04112]
     04113 Meiosis - yeast [PATH:ko04113]
     04114 Oocyte meiosis [PATH:ko04114]
     04210 Apoptosis [PATH:ko04210]
     04214 Apoptosis - fly [PATH:ko04214]
       K14034  NR1H1, EcR; ecdysone receptor
       K14030  NR2B4, usp; nuclear receptor subfamily 2 group B member 4
       K20014  RPR; cell death protein rpr
       K20009  DRONC; caspase Dronc [EC:3.4.22.-]
       K09428  ELF1_2_4; E74-like factor 1/2/4
       K02174  BR-C; broad-complex core protein
       K20015  EIP93F; ecdysone-induced protein 93F, isoform B
       K20016  HID; cell death protein hid
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K02084  APAF1; apoptotic protease-activating factor
       K20010  STRICA; Ser/Thr-rich caspase [EC:3.4.22.-]
       K02561  BOK; Bcl-2-related ovarian killer protein
       K20017  BUFFY; Bcl-2 family protein
       K17065  DNM1L; dynamin 1-like protein [EC:3.6.5.5]
       K06030  MFN2, FZO1; mitofusin 2 [EC:3.6.5.-]
       K08738  CYC; cytochrome c
       K05770  TSPO, BZRP; translocator protein
       K04727  AIFM1, PDCD8; apoptosis-inducing factor 1 [EC:1.-.-.-]
       K07870  RHOT1, ARHT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
       K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
       K03386  PRDX2_4, ahpC; peroxiredoxin 2/4 [EC:1.11.1.24]
       K20018  GRIM; cell death protein Grim
       K20019  SKL; IAP-inhibitory protein Sickle
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K08669  HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K20008  DCP1; death caspase-1 [EC:3.4.22.-]
       K01527  EGD1, BTF3; nascent polypeptide-associated complex subunit beta
       K03262  EIF5; translation initiation factor 5
       K07611  LMNB; lamin B
       K24070  PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
       K16736  BAN; bantam
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K07827  KRAS, KRAS2; GTPase KRas
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04412  STK3, MST2; serine/threonine kinase 3
       K16686  SAV1, Sav; scaffold protein salvador
       K08791  LATS1_2, Wts; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
       K09848  TRAF4; TNF receptor-associated factor 4
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K16678  EGR; eiger
       K16679  WGN; wengen
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K09031  FOSLN; fos-like antigen, invertebrate
       K20216  DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
       K04728  ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
       K06640  ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
       K10149  TP63; tumor protein p63
     04215 Apoptosis - multiple species [PATH:ko04215]
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04726  BID; BH3 interacting domain death agonist
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
       K10132  BBC3, PUMA; Bcl-2-binding component 3
       K02161  BCL2; apoptosis regulator Bcl-2
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K02159  BAX; apoptosis regulator BAX
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K10522  DIABLO, SMAC; diablo
       K08669  HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
       K16943  SEPT4; septin 4
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
       K08731  BIRC5; baculoviral IAP repeat-containing protein 5
       K16679  WGN; wengen
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K20009  DRONC; caspase Dronc [EC:3.4.22.-]
       K20008  DCP1; death caspase-1 [EC:3.4.22.-]
       K02561  BOK; Bcl-2-related ovarian killer protein
       K20017  BUFFY; Bcl-2 family protein
       K20018  GRIM; cell death protein Grim
       K20014  RPR; cell death protein rpr
       K20016  HID; cell death protein hid
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K20104  EGL1; programmed cell death activator egl-1 EGL-1
       K20094  CED-9; cell death protein 9
       K20105  CED-4; cell death protein 4
       K20106  CED-3; cell death protein 3
       K02583  NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
       K08334  BECN, VPS30, ATG6; beclin
       K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
       K04489  CASP3A; caspase 3A [EC:3.4.22.-]
     04216 Ferroptosis [PATH:ko04216]
     04217 Necroptosis [PATH:ko04217]
     04115 p53 signaling pathway [PATH:ko04115]
     04218 Cellular senescence [PATH:ko04218]
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: January 25, 2021