KEGG Orthology (KO)

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 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
   09151 Immune system
 
   09152 Endocrine system
 
   09153 Circulatory system
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
 
   09149 Aging
     04211 Longevity regulating pathway [PATH:ko04211]
     04212 Longevity regulating pathway - worm [PATH:ko04212]
     04213 Longevity regulating pathway - multiple species [PATH:ko04213]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K07201  FOXO1; forkhead box protein O1
       K09408  FOXO3; forkhead box protein O3
       K04564  SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
       K03781  katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
       K08339  ATG5; autophagy-related protein 5
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K11411  SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
       K19805  ILP7; insulin-like peptide 7
       K04565  SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
       K18644  EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
       K03283  HSPA1_6_8; heat shock 70kDa protein 1/6/8
       K09542  CRYAB; crystallin, alpha B
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K19764  INS7; insulin-like neuropeptide
       K08035  FOXA2, HNF3B; forkhead box protein A2, hepatocyte nuclear factor 3-beta
       K19766  HSP16.1; heat shock protein Hsp-16.1/Hsp-16.11
       K19767  HSP16.49; heat shock protein Hsp-16.48/Hsp-16.49
       K19768  HSP12.6; heat shock protein 12.6
       K19769  SIP1; stress-induced protein 1
       K12762  GPR1; G protein-coupled receptor GPR1
       K01768  E4.6.1.1; adenylate cyclase [EC:4.6.1.1]
       K09468  MSN2_4; zinc finger protein MSN2/4
       K12767  RIM15; serine/threonine-protein kinase RIM15 [EC:2.7.11.1]
       K19798  GIS1; transcriptional activator/repressor GIS1
       K19800  SCH9; serine/threonine protein kinase SCH9 [EC:2.7.11.1]
       K03695  clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
       K01440  PNC1; nicotinamidase [EC:3.5.1.19]
       K11121  SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
     03000 Transcription factors [BR:ko03000]
     03021 Transcription machinery [BR:ko03021]
     03019 Messenger RNA biogenesis [BR:ko03019]
       K00565  RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
       K13917  RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
       K04563  CDC28, CDC2; cyclin-dependent kinase [EC:2.7.11.22]
       K02202  CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
       K00987  CEG1; mRNA guanylyltransferase [EC:2.7.7.50]
       K01098  CET1; polynucleotide 5'-triphosphatase [EC:3.6.1.74]
       K14589  CMTR1, FTSJD2, MTR1; cap1 methyltransferase [EC:2.1.1.57]
       K14590  CMTR2, FTSJD1, AFT; cap2 methyltransferase [EC:2.1.1.296]
       K18776  MTR2, MT48; cap2 methyltransferase [EC:2.1.1.296]
       K18777  MTR3, MT57; cap3/cap4 methyltransferase [EC:2.1.1.-]
       K18708  FAM103A1; RNMT-activating mini protein
       K12882  NCBP1, CBP80; nuclear cap-binding protein subunit 1
       K12883  NCBP2, CBP20; nuclear cap-binding protein subunit 2
       K14397  NUDT21, CPSF5, CFIM25; cleavage and polyadenylation specificity factor subunit 5
       K14398  CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
       K14399  CLP1, HERB; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
       K14400  PCF11; pre-mRNA cleavage complex 2 protein Pcf11
       K14401  CPSF1, CFT1; cleavage and polyadenylation specificity factor subunit 1
       K14402  CPSF2, CFT2; cleavage and polyadenylation specificity factor subunit 2
       K14403  CPSF3, YSH1; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
       K14404  CPSF4, YTH1; cleavage and polyadenylation specificity factor subunit 4
       K14405  FIP1L1, FIP1; pre-mRNA 3'-end-processing factor FIP1
       K15541  MPE1; protein MPE1
       K15542  PFS2; polyadenylation factor subunit 2
       K14962  WDR82, SWD2, CPS35; COMPASS component SWD2
       K15543  REF2; RNA end formation protein 2
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K15544  SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
       K14406  CSTF1; cleavage stimulation factor subunit 1
       K14407  CSTF2, RNA15; cleavage stimulation factor subunit 2
       K14408  CSTF3, RNA14; cleavage stimulation factor subunit 3
       K06100  SYMPK; symplekin
       K11086  SNRPB, SMB; small nuclear ribonucleoprotein B and B'
       K11088  SNRPD3, SMD3; small nuclear ribonucleoprotein D3
       K11097  SNRPE, SME; small nuclear ribonucleoprotein E
       K11098  SNRPF, SMF; small nuclear ribonucleoprotein F
       K11099  SNRPG, SMG; small nuclear ribonucleoprotein G
       K25591  LSM10; U7 snRNA-associated Sm-like protein LSm10
       K25592  LSM11; U7 snRNA-associated Sm-like protein LSm11
       K18710  SLBP; histone RNA hairpin-binding protein
       K25593  CASP8AP2; CASP8-associated protein 2
       K15171  SUPT4H1, SPT4; transcription elongation factor SPT4
       K15172  SUPT5H, SPT5; transcription elongation factor SPT5
       K05925  METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
       K23960  METTL14; mRNA m6A methyltransferase non-catalytic subunit
       K24174  METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
       K11393  METTL16, METT10D; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
       K22824  WTAP; pre-mRNA-splicing regulator WTAP
       K22910  VIRMA; protein virilizer
       K13190  RBM15; RNA-binding protein 15
       K22909  ZC3H13; zinc finger CCCH domain-containing protein 13
       K15685  CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
       K14376  PAP; poly(A) polymerase [EC:2.7.7.19]
       K14079  PAPD4, GLD2; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
       K18709  TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
       K10683  BARD1; BRCA1-associated RING domain protein 1
       K13192  RBM26; RNA-binding protein 26
       K19469  FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
       K10767  ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
       K23600  TARDBP, TDP43; TAR DNA-binding protein 43
       K18711  DHX40, DDX40; ATP-dependent RNA helicase DHX40 [EC:3.6.4.13]
       K13102  KIN; DNA/RNA-binding protein KIN17
       K24975  METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
       K23040  METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
       K23033  TENT5A_B, FAM46A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
       K23034  TENT5C, FAM46C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
       K23035  TENT5D, FAM46D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
       K23038  ZC3H14; zinc finger CCCH domain-containing protein 14
       K27103  SRRT, ARS2; serrate RNA effector molecule
       K23039  NAB2; nuclear polyadenylated RNA-binding protein NAB2
       K12876  RBM8A, Y14; RNA-binding protein 8A
       K12877  MAGOH; protein mago nashi
       K12881  THOC4, ALY; THO complex subunit 4
       K12812  DDX39B, UAP56, SUB2; ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13]
       K13025  EIF4A3, FAL1; ATP-dependent RNA helicase [EC:3.6.4.13]
       K25178  CCDC174; coiled-coil domain-containing protein 174
       K14323  CASC3, MLN51; protein CASC3
       K14324  SAP18; histone deacetylase complex subunit SAP18
       K13114  PNN; pinin
       K12875  ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
       K14325  RNPS1; RNA-binding protein with serine-rich domain 1
       K13171  SRRM1, SRM160; serine/arginine repetitive matrix protein 1
       K12878  THOC1; THO complex subunit 1
       K12879  THOC2; THO complex subunit 2
       K12880  THOC3; THO complex subunit 3
       K13174  THOC5; THO complex subunit 5
       K13175  THOC6; THO complex subunit 6
       K13176  THOC7; THO complex subunit 7
       K18712  HPR1; THO complex subunit HPR1
       K18713  THP2; THO complex subunit THP2
       K18714  MFT1; THO complex subunit MFT1
       K23801  PCID2, THP1; nuclear mRNA export protein PCID2/THP1
       K10881  SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
       K11368  ENY2, DC6, SUS1; enhancer of yellow 2 transcription factor
       K10840  CETN2; centrin-2
       K16466  CETN3, CDC31; centrin-3
       K24317  MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
       K23719  SAC3; nuclear mRNA export protein SAC3
       K09291  TPR, MLP1, MLP2; nucleoprotein TPR
       K14298  RAE1, GLE2; mRNA export factor
       K14004  SEC13; protein transport protein SEC13
       K14302  NUP37; nuclear pore complex protein Nup37
       K14304  NUP85; nuclear pore complex protein Nup85
       K14305  NUP43; nuclear pore complex protein Nup43
       K14295  NUP50, NPAP60; nuclear pore complex protein Nup50
       K14308  NUP54, NUP57; nuclear pore complex protein Nup54
       K14306  NUP62, NSP1; nuclear pore complex protein Nup62
       K14318  NUP88; nuclear pore complex protein Nup88
       K14309  NUP93, NIC96; nuclear pore complex protein Nup93
       K14297  NUP98, ADAR2, NUP116; nuclear pore complex protein Nup98-Nup96
       K14301  NUP107, NUP84; nuclear pore complex protein Nup107
       K14300  NUP133; nuclear pore complex protein Nup133
       K14311  NUP188; nuclear pore complex protein Nup188
       K14296  NUP153; nuclear pore complex protein Nup153
       K14312  NUP155, NUP170, NUP157; nuclear pore complex protein Nup155
       K14303  NUP160, NUP120; nuclear pore complex protein Nup160
       K14313  NUP35, NUP53; nuclear pore complex protein Nup53
       K14310  NUP205, NUP192; nuclear pore complex protein Nup205
       K14314  NUP210, GP210; nuclear pore complex protein Nup210
       K14317  NUP214, CAN; nuclear pore complex protein Nup214
       K14316  POM121, NUP121; nuclear pore complex protein Nup121
       K14307  NUPL1, NUP49; nucleoporin p58/p45
       K14321  NUPL2, NUP42, CG1; nucleoporin-like protein 2
       K14315  NDC1, TMEM48; nucleoporin NDC1
       K14299  SEH1; nucleoporin SEH1
       K12172  RANBP2, NUP358; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
       K03345  SENP2, AXAM2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
       K14320  AAAS; aladin
       K18715  NUP159; nucleoporin NUP159
       K18716  NUP42, RIP1; nucleoporin NUP42
       K18717  ASM4, NUP59; nucleoporin ASM4
       K18718  NUP60; nucleoporin NUP60
       K18719  NUP82; nucleoporin NUP82
       K18720  NUP145; nucleoporin NUP145
       K18721  NUP1; nucleoporin NUP1
       K18722  NUP2; nucleoporin NUP2
       K18723  GLE1; nucleoporin GLE1
       K14284  NXF, TAP, MEX67; nuclear RNA export factor
       K14285  NXT1_2, P15; NTF2-related export protein 1/2
       K26564  NPAP1; nuclear pore-associated protein 1
       K14543  MTR2; mRNA transport regulator MTR2
       K18724  POM34; nucleoporin POM34
       K18725  POM152; nucleoporin POM152
       K14017  SNL1; HSP70 co-chaperone SNL1
       K07936  RAN; GTP-binding nuclear protein Ran
       K18646  ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
       K18647  ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
       K05475  TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
       K13088  ELAVL1, HUR; ELAV-like protein 1
       K13208  ELAVL2_3_4; ELAV like protein 2/3/4
       K18726  FAF2, UBXD8; FAS-associated factor 2
       K13525  VCP, CDC48; transitional endoplasmic reticulum ATPase
       K21806  VCPKMT, METTL21D; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
       K18727  TNPO2, IPO3, KPNB2B; transportin-2
       K14290  XPO1, CRM1; exportin-1
       K18460  XPO7, EXP7; exportin-7
       K24115  RANBP17; Ran-binding protein 17
       K14319  RANGAP1; Ran GTPase-activating protein 1
       K14651  TAF15, NPL3; transcription initiation factor TFIID subunit 15
       K03259  EIF4E; translation initiation factor 4E
       K03257  EIF4A; translation initiation factor 4A
       K03260  EIF4G; translation initiation factor 4G
       K03258  EIF4B; translation initiation factor 4B
       K24086  EIF4H; translation initiation factor 4H
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K18644  EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
       K18645  EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3
       K18728  EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
       K18729  ANGEL; protein angel
       K15516  FMR; fragile X mental retardation protein
       K05749  CYFIP; cytoplasmic FMR1 interacting protein
       K13133  GEMIN5; gem associated protein 5
       K14283  TACC3, maskin; transforming acidic coiled-coil-containing protein 3
       K02602  CPEB, ORB; cytoplasmic polyadenylation element-binding protein
       K11594  DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
       K18730  GIGYF; PERQ amino acid-rich with GYF domain-containing protein
       K13126  PABPC; polyadenylate-binding protein
       K14322  PAIP1; polyadenylate-binding protein-interacting protein 1
       K12599  SKI2, SKIV2L; antiviral helicase SKI2 [EC:3.6.4.13]
       K18664  SLH1; antiviral helicase SLH1 [EC:3.6.4.13]
       K23041  DEAF1; deformed epidermal autoregulatory factor 1
       K07575  MCTS, TMA20; malignant T-cell-amplified sequence
       K24272  DENR, TMA22; density-regulated protein
       K16932  APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
       K24978  A1CF; APOBEC1 complementation factor
       K14294  WIBG, PYM; partner of Y14 and mago
       K12741  HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
       K14411  MSI; RNA-binding protein Musashi
       K14416  HBS1; elongation factor 1 alpha-like protein
       K06965  PELO, DOM34, pelA; protein pelota
       K14396  PABPN1, PABP2; polyadenylate-binding protein 2
       K18731  GFD1; mRNA transport factor GFD1
       K18655  DDX19, DBP5; ATP-dependent RNA helicase DDX19/DBP5 [EC:3.6.4.13]
       K18656  DDX25, GRTH; ATP-dependent RNA helicase DDX25 [EC:3.6.4.13]
       K12867  SYF1, XAB2; pre-mRNA-splicing factor SYF1
       K18732  SARNP, CIP29, THO1; SAP domain-containing ribonucleoprotein
       K11493  RCC1; regulator of chromosome condensation
       K18733  LARP6; la-related protein 6
       K21772  PURA; transcriptional activator protein Pur-alpha
       K21799  PURB; transcriptional activator protein Pur-beta
       K22414  POLDIP3; polymerase delta-interacting protein 3
       K22415  ZC3H11; zinc finger CCCH domain-containing protein 11
       K23802  LENG8, THP3; SAC3 family protein LENG8/THP3
       K24823  PATL2; protein PAT1 homolog 2
       K23799  YRA2; RNA annealing protein YRA2
       K03265  ETF1, ERF1; peptide chain release factor subunit 1
       K03267  ERF3, GSPT; peptide chain release factor subunit 3
       K14326  UPF1, RENT1; regulator of nonsense transcripts 1 [EC:3.6.4.13 5.6.2.3]
       K14327  UPF2, RENT2; regulator of nonsense transcripts 2
       K14328  UPF3, RENT3; regulator of nonsense transcripts 3
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K08873  SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
       K11125  SMG5, EST1B; protein SMG5
       K11124  SMG6, EST1A; protein SMG6 [EC:3.1.-.-]
       K14409  SMG7, EST1C; protein SMG7
       K18734  SMG8; protein SMG8
       K18735  SMG9; protein SMG9
       K19539  SECISBP2, SBP2; selenocysteine insertion sequence-binding protein 2
       K20101  DHX34; ATP-dependent RNA helicase DHX34 [EC:3.6.4.13]
       K24887  GTPBP1; GTP-binding protein 1
       K18736  SHE2; SWI5-dependent HO expression protein 2
       K18737  SHE3; SWI5-dependent HO expression protein 3
       K14844  PUF6; pumilio homology domain family member 6
       K18738  HEK; heterogeneous nuclear rnp K-like protein
       K10357  MYO5; myosin V
       K18658  ASH1; transcriptional regulatory protein ASH1
       K18739  BICD; protein bicaudal D
       K18740  EXD1, EGL; exonuclease 3'-5' domain-containing protein 1
       K05692  ACTB_G1; actin beta/gamma 1
       K17269  MBP; myelin basic protein
       K07606  VIM; vimentin
       K14739  MT1_2; metallothionein 1/2
       K04377  MYC; Myc proto-oncogene protein
       K18659  BCD; homeotic protein bicoid
       K05495  GDF1; growth differentiation factor 1
       K10180  TBX6; T-box protein 6
       K18741  NANOS1, NOS1; protein nanos 1
       K18742  OSK; maternal effect protein oskar
       K02524  K10; DNA binding protein (fs(1)K10, female sterile(1)K10)
       K02447  GRK; protein gruken
       K09090  HESN; hairy and enhancer of split, invertebrate
       K12965  ZBP1, DAI; Z-DNA binding protein 1
       K13210  FUBP; far upstream element-binding protein
       K03231  EEF1A; elongation factor 1-alpha
       K03233  EEF1G; elongation factor 1-gamma
       K13158  HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
       K16220  HAX1; HCLS1-associated protein X-1
       K15044  AGFG1; Arf-GAP domain and FG repeats-containing protein 1
       K17597  STAU; double-stranded RNA-binding protein Staufen
       K13197  IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
       K13218  PTBP1, PTB; polypyrimidine tract-binding protein 1
       K03102  SQD; squid
       K13162  PCBP2; poly(rC)-binding protein 2
       K21444  PCBP3_4; poly(rC)-binding protein 3/4
       K18743  CAPRIN1, GPIAP1; caprin-1
       K18744  CAPRIN2, EEG1; caprin-2
       K02177  BRU; bruno
       K18745  EXU; maternal protein exuperantia
       K09276  YBX1, NSEP1; Y-box-binding protein 1
       K18746  CUP; protein cup
       K18747  SXL; protein sex-lethal
       K18748  SSD1; protein SSD1
       K12618  XRN1, SEP1, KEM1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
       K11593  ELF2C, AGO; eukaryotic translation initiation factor 2C
       K17642  DDX3Y; ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13]
       K12614  DDX6, RCK, DHH1; ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13]
       K15686  MEX3, RKHD; RNA-binding protein MEX3 [EC:2.3.2.27]
       K08290  FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
       K18749  LSM14, RAP55, SCD6; protein LSM14
       K12889  PCBP1; poly(rC)-binding protein 1
       K16682  AJUBA, LIMD1, WTIP; LIM domain-containing protein
       K18750  APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
       K18422  MOV10; helicase MOV-10 [EC:3.6.4.13]
       K18751  PNRC2; proline-rich nuclear receptor coactivator 2
       K18752  TNPO1, IPO2, KPNB2; transportin-1
       K15308  TTP; tristetraprolin
       K18753  ZFP36L; butyrate response factor
       K18754  LIN28; protein lin-28
       K04533  HD; huntingtin
       K18755  IPO8, RANBP8; importin-8
       K18756  BICC1, BICC; protein bicaudal C
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K18757  LARP1; la-related protein 1
       K23625  ATXN2_2L; ataxin 2/2L
       K12613  DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
       K12610  DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
       K12611  DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
       K12612  DCP1; mRNA-decapping enzyme subunit 1
       K12620  LSM1; U6 snRNA-associated Sm-like protein LSm1
       K12621  LSM2; U6 snRNA-associated Sm-like protein LSm2
       K12622  LSM3; U6 snRNA-associated Sm-like protein LSm3
       K12623  LSM4; U6 snRNA-associated Sm-like protein LSm4
       K12624  LSM5; U6 snRNA-associated Sm-like protein LSm5
       K12625  LSM6; U6 snRNA-associated Sm-like protein LSm6
       K12626  LSM7; U6 snRNA-associated Sm-like protein LSm7
       K12627  LSM8; U6 snRNA-associated Sm-like protein LSm8
       K10407  KLC; kinesin light chain
       K07374  TUBA; tubulin alpha
       K18412  TNRC6, GW182; trinucleotide repeat-containing gene 6 protein
       K12604  CNOT1, NOT1; CCR4-NOT transcription complex subunit 1
       K12605  CNOT2, NOT2; CCR4-NOT transcription complex subunit 2
       K12580  CNOT3, NOT3; CCR4-NOT transcription complex subunit 3
       K10643  CNOT4, NOT4, MOT2; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
       K12603  CNOT6, CCR4; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
       K12581  CNOT7_8, CAF1, POP2; CCR4-NOT transcription complex subunit 7/8
       K26671  GARRE1; granule associated Rac and RHOG effector protein 1
       K18758  DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
       K12571  PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
       K12572  PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
       K14443  TOB; protein Tob/BTG
       K12617  PATL1, PAT1; DNA topoisomerase 2-associated protein PAT1
       K18759  EDC1_2; enhancer of mRNA-decapping protein 1/2
       K12615  EDC3; enhancer of mRNA-decapping protein 3
       K12616  EDC4; enhancer of mRNA-decapping protein 4
       K18760  NANOS2, NOS2; protein nanos 2
       K18761  NANOS3, NOS3; protein nanos 3
       K10651  TRIM21, SSA1; tripartite motif-containing protein 21 [EC:2.3.2.27]
       K12035  TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
       K03015  RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K18762  ZAR1; zygote arrest protein 1
       K20102  YTHDF; YTH domain-containing family protein
       K13201  TIA1, TIAL1; nucleolysin TIA-1/TIAR
       K17265  G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.3 3.6.4.13]
       K24983  G3BP2; Ras GTPase-activating protein-binding protein 2
       K15026  EIF2A; translation initiation factor 2A
       K03253  EIF3B; translation initiation factor 3 subunit B
       K04373  RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
       K14753  RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K11407  HDAC6; histone deacetylase 6 [EC:3.5.1.98]
       K18404  TDRD3; tudor domain-containing protein 3
       K18763  LARP4; la-related protein 4
       K12619  XRN2, RAT1; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
       K20553  XRN4; 5'-3' exoribonuclease 4 [EC:3.1.13.-]
       K16855  NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
       K12584  DCPS, DCS; m7GpppX diphosphatase [EC:3.6.1.59]
       K25168  HELZ; helicase with zinc finger domain [EC:3.6.4.-]
       K07573  CSL4, EXOSC1; exosome complex component CSL4
       K03679  RRP4, EXOSC2; exosome complex component RRP4
       K03681  RRP40, EXOSC3; exosome complex component RRP40
       K11600  RRP41, EXOSC4, SKI6; exosome complex component RRP41
       K12590  RRP46, EXOSC5; exosome complex component RRP46
       K12587  MTR3, EXOSC6; exosome complex component MTR3
       K12589  RRP42, EXOSC7; exosome complex component RRP42
       K12586  RRP43, EXOSC8, OIP2; exosome complex component RRP43
       K03678  RRP45, EXOSC9; exosome complex component RRP45
       K12585  DIS3, RRP44; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
       K18681  DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
       K12591  RRP6, EXOSC10; exosome complex exonuclease RRP6 [EC:3.1.13.-]
       K12592  C1D, LRP1; exosome complex protein LRP1
       K12593  MPHOSPH6, MPP6; M-phase phosphoprotein 6, animal type
       K12594  MPP6; M-phase phosphoprotein 6, fungi type
       K12595  SKI7; superkiller protein 7
       K20103  DDX60; ATP-dependent RNA helicase DDX60 [EC:3.6.4.13]
       K03514  PAPD5_7, TRF4; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
       K12597  AIR1_2; protein AIR1/2
       K12598  MTR4, SKIV2L2; ATP-dependent RNA helicase DOB1 [EC:3.6.4.13]
       K12596  TRF5; poly(A) RNA polymerase
       K12600  SKI3, TTC37; superkiller protein 3
       K12601  SKI8; superkiller protein 8
       K12602  WDR61, REC14, SKI8; WD repeat-containing protein 61
       K12606  RCD1, CNOT9, CAF40; CCR4-NOT transcription complex subunit 9
       K12607  CNOT10; CCR4-NOT transcription complex subunit 10
       K12608  CAF16; CCR4-NOT complex subunit CAF16
       K12609  CAF120; CCR4-NOT transcriptional complex subunit CAF120
       K01148  PARN, PNLDC1; poly(A)-specific ribonuclease [EC:3.1.13.4]
       K14442  DHX36, RHAU; ATP-dependent RNA helicase DHX36 [EC:3.6.4.13]
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K18764  NOCT, CCRN4L; nocturnin [EC:3.1.3.108]
       K18416  THEX1, ERI1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
       K18417  ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
       K19612  PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
       K22416  IREB2; iron-responsive element-binding protein 2
       K26109  NRDE2; nuclear exosome regulator NRDE2
       K27396  SMG; protein Smaug
       K27407  VTS1; RNA-binding protein VTS1
       K01168  RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
       K10787  RNASE3, ECP; eosinophil cationic protein [EC:3.1.27.-]
       K16632  RNASE4; ribonuclease 4 [EC:3.1.27.-]
       K01172  RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
       K16633  RNASE11; ribonuclease 11 [EC:3.1.27.-]
       K18668  ZC3H12, MCPIP; ribonuclease ZC3H12 [EC:3.1.-.-]
       K23175  RNU2; ribonuclease U2 [EC:4.6.1.20]
       K08300  rne; ribonuclease E [EC:3.1.26.12]
       K08301  rng, cafA; ribonuclease G [EC:3.1.26.-]
       K03685  rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]
       K12574  rnj; ribonuclease J [EC:3.1.-.-]
       K18682  rny; ribonucrease Y [EC:3.1.-.-]
       K12573  rnr, vacB; ribonuclease R [EC:3.1.13.1]
       K01167  rnaSA; ribonuclease T1 [EC:4.6.1.24]
       K13288  orn, REX2, REXO2; oligoribonuclease [EC:3.1.-.-]
       K03698  cbf, cbf1; 3'-5' exoribonuclease [EC:3.1.-.-]
       K03732  rhlB; ATP-dependent RNA helicase RhlB [EC:3.6.4.13]
       K11927  rhlE; ATP-dependent RNA helicase RhlE [EC:3.6.4.13]
       K05592  deaD, cshA; ATP-dependent RNA helicase DeaD [EC:3.6.4.13]
       K18692  cshB; ATP-dependent RNA helicase CshB [EC:3.6.4.13]
       K03654  recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
       K01689  ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11]
       K00962  pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
       K03628  rho; transcription termination factor Rho
       K00850  pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
       K04043  dnaK, HSPA9; molecular chaperone DnaK
       K04077  groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
       K03666  hfq; host factor-I protein
       K00937  ppk1; polyphosphate kinase [EC:2.7.4.1]
       K22468  ppk2; polyphosphate kinase [EC:2.7.4.34]
       K00970  pcnB; poly(A) polymerase [EC:2.7.7.19]
       K08311  nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
       K03563  csrA; carbon storage regulator
       K18765  csrD; RNase E specificity factor CsrD
       K02553  rraA, menG; regulator of ribonuclease activity A
       K09893  rraB; regulator of ribonuclease activity B
       K06958  rapZ; RNase adapter protein RapZ
       K03727  helY; ATP-dependent RNA helicase HelY [EC:3.6.4.-]
       K18502  dsrA; small regulatory RNA DsrA
       K18503  chiX, sroB; small regulatory RNA ChiX
       K18504  arcZ; small regulatory RNA ArcZ
       K15841  glmY; small regulatory RNA GlmY
       K18505  glmZ; small regulatory RNA GlmZ
       K18506  sgrS; small regulatory RNA SgrS
       K18507  ryhB; small regulatory RNA RyhB
       K18508  rybB; small regulatory RNA RybB
       K18509  rydC; small regulatory RNA RydC
       K18510  fnrS; small regulatory RNA FnrS
       K18511  micA; small regulatory RNA MicA
       K18512  micC; small regulatory RNA MicC
       K18513  micF; small regulatory RNA MicF
       K18514  mgrR; small regulatory RNA MgrR
       K18515  csrB; small regulatory RNA CsrB
       K18516  csrC; small regulatory RNA CsrC
       K18517  dicF; small regulatory RNA DicF
       K18518  rprA; small regulatory RNA RprA
       K18519  rseX; small regulatory RNA RseX
       K18520  cyaR, ryeE; small regulatory RNA CyaR
       K18521  gcvB; small regulatory RNA GcvB
       K18522  omrA, rygA; small regulatory RNA OmrA
       K18523  omrB, rygB; small regulatory RNA OmrB
       K18525  gadY; small regulatory RNA GadY
       K18526  istR; sRNA antisense regulator of TisB protein
       K18527  spf; small regulatory RNA Spot 42
       K18528  oxyS; small regulatory RNA OxyS
       K03725  K03725; putative ATP-dependent RNA helicase [EC:3.6.4.-]
     03041 Spliceosome [BR:ko03041]
     03011 Ribosome [BR:ko03011]
     03009 Ribosome biogenesis [BR:ko03009]
     03016 Transfer RNA biogenesis [BR:ko03016]
     03012 Translation factors [BR:ko03012]
     03110 Chaperones and folding catalysts [BR:ko03110]
     04131 Membrane trafficking [BR:ko04131]
     04121 Ubiquitin system [BR:ko04121]
     03051 Proteasome [BR:ko03051]
     03032 DNA replication proteins [BR:ko03032]
     03036 Chromosome and associated proteins [BR:ko03036]
     03400 DNA repair and recombination proteins [BR:ko03400]
     03029 Mitochondrial biogenesis [BR:ko03029]
 
   09183 Protein families: signaling and cellular processes
 
   09185 Viral protein families
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: March 27, 2024