KEGG Orthology (KO)

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 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:ko04110]
     04111 Cell cycle - yeast [PATH:ko04111]
     04112 Cell cycle - Caulobacter [PATH:ko04112]
     04113 Meiosis - yeast [PATH:ko04113]
     04114 Oocyte meiosis [PATH:ko04114]
     04210 Apoptosis [PATH:ko04210]
     04214 Apoptosis - fly [PATH:ko04214]
       K14034  NR1H1, EcR; ecdysone receptor
       K14030  NR2B4, usp; nuclear receptor subfamily 2 group B member 4
       K20014  RPR; cell death protein rpr
       K20009  DRONC; caspase Dronc [EC:3.4.22.-]
       K09428  ELF1_2_4; E74-like factor 1/2/4
       K02174  BR-C; broad-complex core protein
       K20015  EIP93F; ecdysone-induced protein 93F, isoform B
       K20016  HID; cell death protein hid
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K02084  APAF1; apoptotic protease-activating factor
       K20010  STRICA; Ser/Thr-rich caspase [EC:3.4.22.-]
       K02561  BOK; Bcl-2-related ovarian killer protein
       K20017  BUFFY; Bcl-2 family protein
       K17065  DNM1L; dynamin 1-like protein [EC:3.6.5.5]
       K06030  MFN2, FZO1; mitofusin 2 [EC:3.6.5.-]
       K08738  CYC; cytochrome c
       K05770  TSPO, BZRP; translocator protein
       K04727  AIFM1, PDCD8; apoptosis-inducing factor 1 [EC:1.-.-.-]
       K07870  RHOT1, ARHT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
       K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
       K03386  PRDX2_4, ahpC; peroxiredoxin 2/4 [EC:1.11.1.24]
       K20018  GRIM; cell death protein Grim
       K20019  SKL; IAP-inhibitory protein Sickle
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K08669  HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K20008  DCP1; death caspase-1 [EC:3.4.22.-]
       K01527  EGD1, BTF3; nascent polypeptide-associated complex subunit beta
       K03262  EIF5; translation initiation factor 5
       K07611  LMNB; lamin B
       K24070  PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
       K16736  BAN; bantam
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K07827  KRAS, KRAS2; GTPase KRas
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04412  STK3, MST2; serine/threonine kinase 3
       K16686  SAV1, Sav; scaffold protein salvador
       K08791  LATS1_2, Wts; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
       K09848  TRAF4; TNF receptor-associated factor 4
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K16678  EGR; eiger
       K16679  WGN; wengen
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K09031  FOSLN; fos-like antigen, invertebrate
       K20216  DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
       K04728  ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
       K06640  ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
       K10149  TP63; tumor protein p63
     04215 Apoptosis - multiple species [PATH:ko04215]
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04726  BID; BH3 interacting domain death agonist
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
       K10132  BBC3, PUMA; Bcl-2-binding component 3
       K02161  BCL2; apoptosis regulator Bcl-2
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K02159  BAX; apoptosis regulator BAX
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K10522  DIABLO, SMAC; diablo
       K08669  HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
       K16943  SEPT4; septin 4
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
       K08731  BIRC5; baculoviral IAP repeat-containing protein 5
       K16679  WGN; wengen
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K20009  DRONC; caspase Dronc [EC:3.4.22.-]
       K20008  DCP1; death caspase-1 [EC:3.4.22.-]
       K02561  BOK; Bcl-2-related ovarian killer protein
       K20017  BUFFY; Bcl-2 family protein
       K20018  GRIM; cell death protein Grim
       K20014  RPR; cell death protein rpr
       K20016  HID; cell death protein hid
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K20104  EGL1; programmed cell death activator egl-1 EGL-1
       K20094  CED-9; cell death protein 9
       K20105  CED-4; cell death protein 4
       K20106  CED-3; cell death protein 3
       K02583  NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
       K08334  BECN, VPS30, ATG6; beclin
       K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
       K04489  CASP3A; caspase 3A [EC:3.4.22.-]
     04216 Ferroptosis [PATH:ko04216]
     04217 Necroptosis [PATH:ko04217]
     04115 p53 signaling pathway [PATH:ko04115]
     04218 Cellular senescence [PATH:ko04218]
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

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Last updated: January 23, 2021