KEGG Orthology (KO)

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 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:ko04110]
     04111 Cell cycle - yeast [PATH:ko04111]
     04112 Cell cycle - Caulobacter [PATH:ko04112]
     04113 Meiosis - yeast [PATH:ko04113]
     04114 Oocyte meiosis [PATH:ko04114]
     04210 Apoptosis [PATH:ko04210]
     04214 Apoptosis - fly [PATH:ko04214]
     04215 Apoptosis - multiple species [PATH:ko04215]
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04726  BID; BH3 interacting domain death agonist
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
       K10132  BBC3, PUMA; Bcl-2-binding component 3
       K02161  BCL2; apoptosis regulator Bcl-2
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K02159  BAX; apoptosis regulator BAX
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K10522  DIABLO, SMAC; diablo
       K08669  HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
       K16943  SEPT4; septin 4
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
       K08731  BIRC5; baculoviral IAP repeat-containing protein 5
       K16679  WGN; wengen
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K20009  DRONC; caspase Dronc [EC:3.4.22.-]
       K20008  DCP1; death caspase-1 [EC:3.4.22.-]
       K02561  BOK; Bcl-2-related ovarian killer protein
       K20017  BUFFY; Bcl-2 family protein
       K20018  GRIM; cell death protein Grim
       K20014  RPR; cell death protein rpr
       K20016  HID; cell death protein hid
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K20104  EGL1; programmed cell death activator egl-1 EGL-1
       K20094  CED-9; cell death protein 9
       K20105  CED-4; cell death protein 4
       K20106  CED-3; cell death protein 3
       K02583  NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
       K08334  BECN, VPS30, ATG6; beclin
       K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
       K04489  CASP3A; caspase 3A [EC:3.4.22.-]
     04216 Ferroptosis [PATH:ko04216]
     04217 Necroptosis [PATH:ko04217]
     04115 p53 signaling pathway [PATH:ko04115]
     04218 Cellular senescence [PATH:ko04218]
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
   09151 Immune system
 
   09152 Endocrine system
 
   09153 Circulatory system
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
     04320 Dorso-ventral axis formation [PATH:ko04320]
     04360 Axon guidance [PATH:ko04360]
     04361 Axon regeneration [PATH:ko04361]
       K04851  CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K20105  CED-4; cell death protein 4
       K20106  CED-3; cell death protein 3
       K10693  MYCBP2, PAM; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
       K04422  MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
       K09442  SPDEF; SAM pointed domain-containing ETS transcription factor
       K23479  CCAAT/enhancer binding protein (C/EBP), other
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K12494  PSD; PH and SEC7 domain-containing protein
       K10393  KIF2_24, MCAK; kinesin family member 2/24
       K23439  AGBL4, CCP6; cytosolic carboxypeptidase protein 6 [EC:3.4.17.24]
       K04459  DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
       K23489  SVH1, Teq; HGF/MSP/plasminogen-like protein
       K04417  MAP3K9, MLK1; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K09031  FOSLN; fos-like antigen, invertebrate
       K15528  FAAH; fatty acid amide hydrolase [EC:3.5.1.99]
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K04163  HTR7; 5-hydroxytryptamine receptor 7
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K04513  RHOA; Ras homolog gene family, member A
       K00901  dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K00502  TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
       K01593  DDC, TDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K09408  FOXO3; forkhead box protein O3
       K16336  SDC2, CD362; syndecan 2
       K06704  ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
       K02599  NOTCH1; Notch 1
       K04505  PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K06839  SLIT2; slit 2
       K05110  EPHB1, ELK, NET; Eph receptor B1 [EC:2.7.10.1]
       K06754  ROBO2; roundabout, axon guidance receptor 2
       K06843  NTN1; netrin 1
       K23487  EVL; Ena/VASP-like protein
       K23488  RAPH1; Ras-associated and pleckstrin homology domains-containing protein 1
       K19862  NCK2, GRB4; NCK adaptor protein 2
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K16980  MIRLET7; microRNA let-7
       K12035  TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
       K11593  ELF2C, AGO; eukaryotic translation initiation factor 2C
       K23480  ZNF362_384, LIN-29; zinc finger protein 362/384
     04380 Osteoclast differentiation [PATH:ko04380]
 
   09149 Aging
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

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Last updated: January 22, 2021