 1. Oxidoreductases
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 2. Transferases
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2.1 Transferring one-carbon groups
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2.2 Transferring aldehyde or ketonic groups
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2.3 Acyltransferases
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2.4 Glycosyltransferases
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2.5 Transferring alkyl or aryl groups, other than methyl groups
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2.6 Transferring nitrogenous groups
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2.7 Transferring phosphorus-containing groups
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2.7.1 Phosphotransferases with an alcohol group as acceptor
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2.7.2 Phosphotransferases with a carboxy group as acceptor
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2.7.3 Phosphotransferases with a nitrogenous group as acceptor
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2.7.4 Phosphotransferases with a phosphate group as acceptor
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2.7.6 Diphosphotransferases
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2.7.7 Nucleotidyltransferases
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2.7.7.1 nicotinamide-nucleotide adenylyltransferase
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2.7.7.2 FAD synthase
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2.7.7.3 pantetheine-phosphate adenylyltransferase
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2.7.7.4 sulfate adenylyltransferase
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2.7.7.5 sulfate adenylyltransferase (ADP)
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2.7.7.6 DNA-directed RNA polymerase
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2.7.7.7 DNA-directed DNA polymerase
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 K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K02331 POL5, MYBBP1A; DNA polymerase phi [EC:2.7.7.7]
K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
K02334 dpo; DNA polymerase bacteriophage-type [EC:2.7.7.7]
K02335 polA; DNA polymerase I [EC:2.7.7.7]
K02336 polB; DNA polymerase II [EC:2.7.7.7]
K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
K02350 REV3L, POLZ; DNA polymerase zeta [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K03508 POLZ2, rev7; DNA polymerase zeta [EC:2.7.7.7]
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
K14159 rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
K18942 gp43; Straboviridae DNA polymerase [EC:2.7.7.7]
K18963 pol; Baculoviridae DNA polymerase [EC:2.7.7.7]
K18964 UL30, UL54, BALF5, U38; Herpesviridae DNA polymerase catalytic subunit [EC:2.7.7.7]
K21037 P; Hepadnaviridae DNA polymerase / reverse transcriptase / ribonuclease H [EC:2.7.7.7 2.7.7.49 3.1.26.4]
K21237 gp2; Podoviridae DNA polymerase [EC:2.7.7.7]
K21238 gp5; Autographiviridae DNA-directed DNA polymerase [EC:2.7.7.7]
K21314 pol; Demerecviridae DNA polymerase [EC:2.7.7.7]
K21923 POL; Adenoviridae DNA polymerase [EC:2.7.7.7]
K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
K24802 RT; HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13]
K25055 RT; HTLV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.4]
K25268 POL; Poxviridae DNA polymerase [EC:2.7.7.7 3.1.11.-]
K26366 ORF1; Ascoviridae DNA polymerase [EC:2.7.7.7]
K26367 FV3-060R; Iridoviridae putative DNA polymerase [EC:2.7.7.7]
K26378 O174L; Asfivirus repair DNA polymerase X [EC:2.7.7.7]
K26379 DPOL; Asfivirus DNA polymerase beta [EC:2.7.7.7]
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2.7.7.8 polyribonucleotide nucleotidyltransferase
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2.7.7.9 UTP---glucose-1-phosphate uridylyltransferase
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2.7.7.10 UTP---hexose-1-phosphate uridylyltransferase
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2.7.7.11 UTP---xylose-1-phosphate uridylyltransferase
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2.7.7.12 UDP-glucose---hexose-1-phosphate uridylyltransferase
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2.7.7.13 mannose-1-phosphate guanylyltransferase
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2.7.7.14 ethanolamine-phosphate cytidylyltransferase
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2.7.7.15 choline-phosphate cytidylyltransferase
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2.7.7.18 nicotinate-nucleotide adenylyltransferase
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2.7.7.19 polynucleotide adenylyltransferase
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2.7.7.22 mannose-1-phosphate guanylyltransferase (GDP)
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2.7.7.23 UDP-N-acetylglucosamine diphosphorylase
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2.7.7.24 glucose-1-phosphate thymidylyltransferase
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2.7.7.27 glucose-1-phosphate adenylyltransferase
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2.7.7.28 nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase
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2.7.7.30 fucose-1-phosphate guanylyltransferase
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2.7.7.31 DNA nucleotidylexotransferase
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2.7.7.32 galactose-1-phosphate thymidylyltransferase
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2.7.7.33 glucose-1-phosphate cytidylyltransferase
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2.7.7.34 glucose-1-phosphate guanylyltransferase
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2.7.7.35 ADP ribose phosphorylase
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2.7.7.36 aldose-1-phosphate adenylyltransferase
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2.7.7.37 aldose-1-phosphate nucleotidyltransferase
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2.7.7.38 3-deoxy-manno-octulosonate cytidylyltransferase
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2.7.7.39 glycerol-3-phosphate cytidylyltransferase
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2.7.7.40 D-ribitol-5-phosphate cytidylyltransferase
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2.7.7.41 phosphatidate cytidylyltransferase
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2.7.7.42 [glutamine synthetase] adenylyltransferase
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2.7.7.43 N-acylneuraminate cytidylyltransferase
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2.7.7.44 glucuronate-1-phosphate uridylyltransferase
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2.7.7.45 guanosine-triphosphate guanylyltransferase
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2.7.7.46 gentamicin 2''-nucleotidyltransferase
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2.7.7.47 streptomycin 3''-adenylyltransferase
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2.7.7.48 RNA-directed RNA polymerase
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2.7.7.49 RNA-directed DNA polymerase
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2.7.7.50 mRNA guanylyltransferase
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2.7.7.51 adenylylsulfate---ammonia adenylyltransferase
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2.7.7.52 RNA uridylyltransferase
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2.7.7.53 ATP adenylyltransferase
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2.7.7.56 tRNA nucleotidyltransferase
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2.7.7.57 N-methylphosphoethanolamine cytidylyltransferase
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2.7.7.59 [protein-PII] uridylyltransferase
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2.7.7.60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
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2.7.7.61 citrate lyase holo-[acyl-carrier protein] synthase
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2.7.7.62 adenosylcobinamide-phosphate guanylyltransferase
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2.7.7.64 UTP-monosaccharide-1-phosphate uridylyltransferase
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2.7.7.65 diguanylate cyclase
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2.7.7.66 malonate decarboxylase holo-[acyl-carrier protein] synthase
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2.7.7.67 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
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2.7.7.68 2-phospho-L-lactate guanylyltransferase
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2.7.7.69 GDP-L-galactose/GDP-D-glucose: hexose 1-phosphate guanylyltransferase
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2.7.7.70 D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase
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2.7.7.71 D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase
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2.7.7.72 CCA tRNA nucleotidyltransferase
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2.7.7.73 sulfur carrier protein ThiS adenylyltransferase
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2.7.7.74 1L-myo-inositol 1-phosphate cytidylyltransferase
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2.7.7.75 molybdopterin adenylyltransferase
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2.7.7.76 molybdenum cofactor cytidylyltransferase
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2.7.7.77 molybdenum cofactor guanylyltransferase
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2.7.7.78 GDP-D-glucose phosphorylase
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2.7.7.79 tRNAHis guanylyltransferase
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2.7.7.80 molybdopterin-synthase adenylyltransferase
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2.7.7.81 pseudaminic acid cytidylyltransferase
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2.7.7.82 CMP-N,N'-diacetyllegionaminic acid synthase
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2.7.7.83 UDP-N-acetylgalactosamine diphosphorylase
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2.7.7.84 2'-5' oligoadenylate synthase
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2.7.7.85 diadenylate cyclase
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2.7.7.86 cyclic GMP-AMP synthase
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2.7.7.87 L-threonylcarbamoyladenylate synthase
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2.7.7.88 GDP polyribonucleotidyltransferase
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2.7.7.89 [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
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2.7.7.90 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase
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2.7.7.91 valienol-1-phosphate guanylyltransferase
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2.7.7.92 3-deoxy-D-glycero-D-galacto-nonulopyranosonate cytidylyltransferase
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2.7.7.93 phosphonoformate cytidylyltransferase
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2.7.7.96 ADP-D-ribose pyrophosphorylase
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2.7.7.97 3-hydroxy-4-methylanthranilate adenylyltransferase
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2.7.7.99 N-acetyl-alpha-D-muramate 1-phosphate uridylyltransferase
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2.7.7.100 SAMP-activating enzyme
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2.7.7.101 DNA primase DnaG
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2.7.7.102 DNA primase AEP
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2.7.7.103 L-glutamine-phosphate cytidylyltransferase
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2.7.7.104 2-hydroxyethylphosphonate cytidylyltransferase
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2.7.7.105 phosphoenolpyruvate guanylyltransferase
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2.7.7.106 3-phospho-D-glycerate guanylyltransferase
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2.7.7.107 (2-aminoethyl)phosphonate cytidylyltransferase
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2.7.7.108 protein adenylyltransferase
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2.7.8 Transferases for other substituted phosphate groups
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2.7.9 Phosphotransferases with paired acceptors
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2.7.10 Protein-tyrosine kinases
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2.7.11 Protein-serine/threonine kinases
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2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
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2.7.13 Protein-histidine kinases
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2.7.14 Protein-arginine kinases
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2.7.99 Other protein kinases
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2.8 Transferring sulfur-containing groups
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2.9 Transferring selenium-containing groups
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2.10 Transferring molybdenum- or tungsten-containing groups
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3. Hydrolases
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4. Lyases
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5. Isomerases
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6. Ligases
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7. Translocases
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Enzymes