1. Oxidoreductases
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2. Transferases
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2.1 Transferring one-carbon groups
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2.2 Transferring aldehyde or ketonic groups
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2.3 Acyltransferases
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2.4 Glycosyltransferases
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2.5 Transferring alkyl or aryl groups, other than methyl groups
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2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
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2.5.1.1 dimethylallyltranstransferase
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2.5.1.2 thiamine pyridinylase
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2.5.1.3 thiamine phosphate synthase
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2.5.1.5 galactose-6-sulfurylase
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2.5.1.6 methionine adenosyltransferase
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2.5.1.7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase
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2.5.1.9 riboflavin synthase
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2.5.1.10 (2E,6E)-farnesyl diphosphate synthase
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2.5.1.15 dihydropteroate synthase
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2.5.1.16 spermidine synthase
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2.5.1.17 corrinoid adenosyltransferase
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2.5.1.18 glutathione transferase
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2.5.1.19 3-phosphoshikimate 1-carboxyvinyltransferase
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2.5.1.20 rubber cis-polyprenylcistransferase
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2.5.1.21 squalene synthase
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2.5.1.22 spermine synthase
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2.5.1.23 sym-norspermidine synthase
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2.5.1.24 discadenine synthase
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2.5.1.25 tRNA-uridine aminocarboxypropyltransferase
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2.5.1.26 alkylglycerone-phosphate synthase
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2.5.1.27 adenylate dimethylallyltransferase (AMP-dependent)
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2.5.1.28 dimethylallylcistransferase
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2.5.1.29 geranylgeranyl diphosphate synthase
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2.5.1.30 heptaprenyl diphosphate synthase
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2.5.1.31 ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
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2.5.1.32 15-cis-phytoene synthase
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2.5.1.34 4-dimethylallyltryptophan synthase
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2.5.1.35 aspulvinone dimethylallyltransferase
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2.5.1.36 trihydroxypterocarpan dimethylallyltransferase
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2.5.1.38 isonocardicin synthase
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2.5.1.39 4-hydroxybenzoate polyprenyltransferase
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2.5.1.41 phosphoglycerol geranylgeranyltransferase
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2.5.1.42 geranylgeranylglycerol-phosphate geranylgeranyltransferase
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2.5.1.43 nicotianamine synthase
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2.5.1.44 homospermidine synthase
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2.5.1.45 homospermidine synthase (spermidine-specific)
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2.5.1.46 deoxyhypusine synthase
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2.5.1.47 cysteine synthase
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2.5.1.48 cystathionine gamma-synthase
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2.5.1.49 O-acetylhomoserine aminocarboxypropyltransferase
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2.5.1.50 zeatin 9-aminocarboxyethyltransferase
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2.5.1.51 beta-pyrazolylalanine synthase
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2.5.1.52 L-mimosine synthase
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2.5.1.53 uracilylalanine synthase
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2.5.1.54 3-deoxy-7-phosphoheptulonate synthase
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K01626 E2.5.1.54, aroF, aroG, aroH; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
K03856 AROA2, aroA; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
K13853 aroG, aroA; 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase [EC:2.5.1.54 5.4.99.5]
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2.5.1.55 3-deoxy-8-phosphooctulonate synthase
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2.5.1.56 N-acetylneuraminate synthase
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2.5.1.57 N-acylneuraminate-9-phosphate synthase
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2.5.1.58 protein farnesyltransferase
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2.5.1.59 protein geranylgeranyltransferase type I
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2.5.1.60 protein geranylgeranyltransferase type II
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2.5.1.61 hydroxymethylbilane synthase
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2.5.1.62 chlorophyll synthase
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2.5.1.63 adenosyl-fluoride synthase
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2.5.1.65 O-phosphoserine sulfhydrylase
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2.5.1.66 N2-(2-carboxyethyl)arginine synthase
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2.5.1.67 chrysanthemyl diphosphate synthase
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2.5.1.68 (2Z,6E)-farnesyl diphosphate synthase
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2.5.1.69 lavandulyl diphosphate synthase
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2.5.1.70 naringenin 8-dimethylallyltransferase
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2.5.1.71 leachianone-G 2''-dimethylallyltransferase
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2.5.1.72 quinolinate synthase
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2.5.1.73 O-phospho-L-seryl-tRNA:Cys-tRNA synthase
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2.5.1.74 1,4-dihydroxy-2-naphthoate polyprenyltransferase
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2.5.1.75 tRNA dimethylallyltransferase
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2.5.1.76 cysteate synthase
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2.5.1.78 6,7-dimethyl-8-ribityllumazine synthase
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2.5.1.79 thermospermine synthase
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2.5.1.80 7-dimethylallyltryptophan synthase
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2.5.1.81 geranylfarnesyl diphosphate synthase
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2.5.1.82 hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
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2.5.1.83 hexaprenyl diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
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2.5.1.84 all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific]
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2.5.1.85 all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
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2.5.1.86 trans,polycis-decaprenyl diphosphate synthase
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2.5.1.87 ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific]
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2.5.1.88 trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific]
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2.5.1.89 tritrans,polycis-undecaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
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2.5.1.90 all-trans-octaprenyl-diphosphate synthase
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2.5.1.91 all-trans-decaprenyl-diphosphate synthase
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2.5.1.92 (2Z,6Z)-farnesyl diphosphate synthase
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2.5.1.93 4-hydroxybenzoate geranyltransferase
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2.5.1.94 adenosyl-chloride synthase
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2.5.1.95 xanthan ketal pyruvate transferase
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2.5.1.96 4,4'-diapophytoene synthase
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2.5.1.97 pseudaminic acid synthase
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2.5.1.98 Rhizobium leguminosarum exopolysaccharide glucosyl ketal-pyruvate-transferase
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2.5.1.100 fumigaclavine A dimethylallyltransferase
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2.5.1.101 N,N'-diacetyllegionaminate synthase
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2.5.1.102 geranyl-pyrophosphate---olivetolic acid geranyltransferase
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2.5.1.103 presqualene diphosphate synthase
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2.5.1.104 N1-aminopropylagmatine synthase
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2.5.1.105 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase
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2.5.1.106 tryprostatin B synthase
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2.5.1.107 verruculogen prenyltransferase
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2.5.1.108 2-(3-amino-3-carboxypropyl)histidine synthase
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2.5.1.109 brevianamide F prenyltransferase (deoxybrevianamide E-forming)
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2.5.1.110 12alpha,13alpha-dihydroxyfumitremorgin C prenyltransferase
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2.5.1.111 4-hydroxyphenylpyruvate 3-dimethylallyltransferase
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2.5.1.112 adenylate dimethylallyltransferase (ADP/ATP-dependent)
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2.5.1.113 [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase
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2.5.1.114 tRNAPhe (4-demethylwyosine37-C7) aminocarboxypropyltransferase
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2.5.1.115 homogentisate phytyltransferase
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2.5.1.116 homogentisate geranylgeranyltransferase
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2.5.1.117 homogentisate solanesyltransferase
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2.5.1.118 beta-(isoxazolin-5-on-2-yl)-L-alanine synthase
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2.5.1.119 beta-(isoxazolin-5-on-4-yl)-L-alanine synthase
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2.5.1.120 aminodeoxyfutalosine synthase
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2.5.1.121 5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase
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2.5.1.122 4-O-dimethylallyl-L-tyrosine synthase
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2.5.1.123 flaviolin linalyltransferase
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2.5.1.124 6-linalyl-2-O,3-dimethylflaviolin synthase
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2.5.1.125 7-geranyloxy-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione synthase
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2.5.1.126 norspermine synthase
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2.5.1.127 caldopentamine synthase
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2.5.1.128 N4-bis(aminopropyl)spermidine synthase
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2.5.1.129 flavin prenyltransferase
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2.5.1.130 2-carboxy-1,4-naphthoquinone phytyltransferase
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2.5.1.131 (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
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2.5.1.132 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase
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2.5.1.133 bacteriochlorophyll a synthase
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2.5.1.134 cystathionine beta-synthase (O-acetyl-L-serine)
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2.5.1.135 validamine 7-phosphate valienyltransferase
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2.5.1.136 2-acylphloroglucinol 4-prenyltransferase
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2.5.1.137 2-acyl-4-prenylphloroglucinol 6-prenyltransferase
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2.5.1.138 coumarin 8-geranyltransferase
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2.5.1.139 umbelliferone 6-dimethylallyltransferase
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2.5.1.140 N-(2-amino-2-carboxyethyl)-L-glutamate synthase
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2.5.1.141 heme o synthase
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2.5.1.142 nerylneryl diphosphate synthase
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2.5.1.143 pyridinium-3,5-biscarboxylic acid mononucleotide synthase
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2.5.1.144 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent)
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2.5.1.145 phosphatidylglycerol---prolipoprotein diacylglyceryl transferase
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2.5.1.146 3-geranyl-3-[(Z)-2-isocyanoethenyl]indole synthase
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2.5.1.147 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase
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2.5.1.148 lycopaoctaene synthase
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2.5.1.149 lycopene elongase/hydratase (flavuxanthin-forming)
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2.5.1.150 lycopene elongase/hydratase (dihydrobisanhydrobacterioruberin-forming)
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2.5.1.151 alkylcobalamin dealkylase
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2.5.1.152 D-histidine 2-aminobutanoyltransferase
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2.5.1.153 adenosine tuberculosinyltransferase
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2.5.1.154 corrinoid adenosyltransferase EutT
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2.5.1.155 phosphoglycerol geranylfarnesyltransferase
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2.5.1.156 geranylfarnesylglycerol-phosphate geranylfarnesyltransferase
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2.5.1.157 rRNA small subunit aminocarboxypropyltransferase
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2.5.1.158 hexaprenyl diphosphate synthase (prenyl-diphosphate specific)
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2.5.1.159 hapalindole G dimethylallyltransferase
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2.6 Transferring nitrogenous groups
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2.7 Transferring phosphorus-containing groups
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2.8 Transferring sulfur-containing groups
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2.9 Transferring selenium-containing groups
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2.10 Transferring molybdenum- or tungsten-containing groups
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3. Hydrolases
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4. Lyases
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5. Isomerases
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5.1 Racemases and epimerases
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5.2 cis-trans-Isomerases
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5.3 Intramolecular oxidoreductases
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5.4 Intramolecular transferases
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5.4.1 Transferring acyl groups
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5.4.2 Phosphotransferases (phosphomutases)
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5.4.3 Transferring amino groups
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5.4.4 Transferring hydroxy groups
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5.4.99 Transferring other groups
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5.4.99.1 methylaspartate mutase
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5.4.99.2 methylmalonyl-CoA mutase
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5.4.99.3 2-acetolactate mutase
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5.4.99.4 2-methyleneglutarate mutase
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5.4.99.5 chorismate mutase
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K01850 E5.4.99.5; chorismate mutase [EC:5.4.99.5]
K04092 tyrA1; chorismate mutase [EC:5.4.99.5]
K04093 pheA1; chorismate mutase [EC:5.4.99.5]
K04516 AROA1, aroA; chorismate mutase [EC:5.4.99.5]
K06208 aroH; chorismate mutase [EC:5.4.99.5]
K06209 pheB; chorismate mutase [EC:5.4.99.5]
K13853 aroG, aroA; 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase [EC:2.5.1.54 5.4.99.5]
K14170 pheA; chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51]
K14187 tyrA; chorismate mutase / prephenate dehydrogenase [EC:5.4.99.5 1.3.1.12]
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5.4.99.7 lanosterol synthase
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5.4.99.8 cycloartenol synthase
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5.4.99.9 UDP-galactopyranose mutase
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5.4.99.11 isomaltulose synthase
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5.4.99.12 tRNA pseudouridine38-40 synthase
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5.4.99.13 isobutyryl-CoA mutase
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5.4.99.14 4-carboxymethyl-4-methylbutenolide mutase
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5.4.99.15 (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase
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5.4.99.16 maltose alpha-D-glucosyltransferase
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5.4.99.17 squalene---hopene cyclase
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5.4.99.18 5-(carboxyamino)imidazole ribonucleotide mutase
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5.4.99.19 16S rRNA pseudouridine516 synthase
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5.4.99.20 23S rRNA pseudouridine2457 synthase
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5.4.99.21 23S rRNA pseudouridine2604 synthase
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5.4.99.22 23S rRNA pseudouridine2605 synthase
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5.4.99.23 23S rRNA pseudouridine1911/1915/1917 synthase
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5.4.99.24 23S rRNA pseudouridine955/2504/2580 synthase
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5.4.99.25 tRNA pseudouridine55 synthase
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5.4.99.26 tRNA pseudouridine65 synthase
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5.4.99.27 tRNA pseudouridine13 synthase
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5.4.99.28 tRNA pseudouridine32 synthase
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5.4.99.29 23S rRNA pseudouridine746 synthase
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5.4.99.30 UDP-arabinopyranose mutase
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5.4.99.31 thalianol synthase
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5.4.99.32 protostadienol synthase
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5.4.99.33 cucurbitadienol synthase
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5.4.99.34 germanicol synthase
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5.4.99.35 taraxerol synthase
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5.4.99.36 isomultiflorenol synthase
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5.4.99.37 dammaradiene synthase
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5.4.99.38 camelliol C synthase
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5.4.99.39 beta-amyrin synthase
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5.4.99.40 alpha-amyrin synthase
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5.4.99.41 lupeol synthase
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5.4.99.42 tRNA pseudouridine31 synthase
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5.4.99.43 21S rRNA pseudouridine2819 synthase
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5.4.99.44 mitochondrial tRNA pseudouridine27/28 synthase
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5.4.99.45 tRNA pseudouridine38/39 synthase
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5.4.99.46 shionone synthase
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5.4.99.47 parkeol synthase
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5.4.99.48 achilleol B synthase
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5.4.99.49 glutinol synthase
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5.4.99.50 friedelin synthase
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5.4.99.51 baccharis oxide synthase
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5.4.99.52 alpha-seco-amyrin synthase
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5.4.99.53 marneral synthase
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5.4.99.54 beta-seco-amyrin synthase
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5.4.99.55 delta-amyrin synthase
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5.4.99.56 tirucalladienol synthase
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5.4.99.57 baruol synthase
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5.4.99.58 methylornithine synthase
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5.4.99.59 dTDP-fucopyranose mutase
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5.4.99.60 cobalt-precorrin-8 methylmutase
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5.4.99.61 precorrin-8X methylmutase
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5.4.99.62 D-ribose pyranase
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5.4.99.63 ethylmalonyl-CoA mutase
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5.4.99.64 2-hydroxyisobutanoyl-CoA mutase
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5.4.99.65 pre-alpha-onocerin synthase
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5.4.99.66 alpha-onocerin synthase
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5.4.99.67 4-amino-4-deoxychorismate mutase
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5.5 Intramolecular lyases
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5.6 Isomerases altering macromolecular conformation
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5.99 Other isomerases
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6. Ligases
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7. Translocases
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