KEGG Orthology (KO) - Loxodonta africana (African savanna elephant)

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     KO 
 09100 Metabolism

 





   09101 Carbohydrate metabolism





 







   09102 Energy metabolism





 







   09103 Lipid metabolism





 







   09104 Nucleotide metabolism





 







   09105 Amino acid metabolism





     00250 Alanine, aspartate and glutamate metabolism [PATH:lav00250]





     00260 Glycine, serine and threonine metabolism [PATH:lav00260]





     00270 Cysteine and methionine metabolism [PATH:lav00270]





     00280 Valine, leucine and isoleucine degradation [PATH:lav00280]





     00290 Valine, leucine and isoleucine biosynthesis [PATH:lav00290]





     00300 Lysine biosynthesis





     00310 Lysine degradation [PATH:lav00310]





     00220 Arginine biosynthesis [PATH:lav00220]





     00330 Arginine and proline metabolism [PATH:lav00330]





     00340 Histidine metabolism [PATH:lav00340]





     00350 Tyrosine metabolism [PATH:lav00350]





       100666637 GOT1; aspartate aminotransferase, cytoplasmic
       100674813 GOT1L1; putative aspartate aminotransferase, cytoplasmic 2
       100662129 GOT2; aspartate aminotransferase, mitochondrial isoform X1
       100670549 TAT; tyrosine aminotransferase
       100665294 IL4I1; LOW QUALITY PROTEIN: L-amino-acid oxidase
       100677374 L-amino-acid oxidase-like
       100657023 L-amino-acid oxidase-like
       100668207 HPD; 4-hydroxyphenylpyruvate dioxygenase
       100658305 HGD; homogentisate 1,2-dioxygenase
       100655538 GSTZ1; maleylacetoacetate isomerase isoform X1
       100677367 FAH; fumarylacetoacetase
       100676924 TYR; tyrosinase
       100656003 DCT; L-dopachrome tautomerase
       100670218 TYRP1; 5,6-dihydroxyindole-2-carboxylic acid oxidase
       100677538 DDC; aromatic-L-amino-acid decarboxylase
       100675803 DBH; dopamine beta-hydroxylase
       100655935 PNMT; phenylethanolamine N-methyltransferase
       100672368 COMT; LOW QUALITY PROTEIN: catechol O-methyltransferase
       100665450 TOMT; transmembrane O-methyltransferase
       100661468 MAOB; amine oxidase [flavin-containing] B isoform X1
       100662037 amine oxidase [flavin-containing] A
       100675868 AOC2; retina-specific copper amine oxidase
       100676341 AOC3; membrane primary amine oxidase
       100673883 membrane primary amine oxidase-like
       100667345 ALDH3B1; aldehyde dehydrogenase family 3 member B1 isoform X4
       100657867 LOW QUALITY PROTEIN: aldehyde dehydrogenase, dimeric NADP-preferring
       100667915 LOW QUALITY PROTEIN: aldehyde dehydrogenase family 3 member B1-like
       100658769 LOW QUALITY PROTEIN: alcohol dehydrogenase class 4 mu/sigma chain
       100657356 alcohol dehydrogenase E chain
       100658488 alcohol dehydrogenase E chain-like
       100657066 alcohol dehydrogenase E chain-like isoform X1
       100657924 alcohol dehydrogenase E chain-like
       100670136 alcohol dehydrogenase class-3
       100673473 LOW QUALITY PROTEIN: alcohol dehydrogenase 6-like
       100654315 TPO; thyroid peroxidase isoform X1
       100665288 aldehyde oxidase 4-like
       100665571 AOX1; aldehyde oxidase 1
       100662726 aldehyde oxidase 3-like
       100665003 LOW QUALITY PROTEIN: aldehyde oxidase 2-like
       100672838 FAHD1; acylpyruvase FAHD1, mitochondrial
       104845409 MIF; LOW QUALITY PROTEIN: macrophage migration inhibitory factor



K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
K14455 GOT2; aspartate aminotransferase, mitochondrial [EC:2.6.1.1]
K00815 TAT; tyrosine aminotransferase [EC:2.6.1.5]
K03334 IL4I1; L-amino-acid oxidase [EC:1.4.3.2]
K03334 IL4I1; L-amino-acid oxidase [EC:1.4.3.2]
K03334 IL4I1; L-amino-acid oxidase [EC:1.4.3.2]
K00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]
K00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5]
K01800 maiA; maleylacetoacetate isomerase [EC:5.2.1.2]
K01555 FAH; fumarylacetoacetase [EC:3.7.1.2]
K00505 TYR; tyrosinase [EC:1.14.18.1]
K01827 DCT; dopachrome tautomerase [EC:5.3.3.12]
K00506 TYRP1; tyrosinase-related protein 1 [EC:1.14.18.-]
K01593 DDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
K00503 DBH; dopamine beta-monooxygenase [EC:1.14.17.1]
K00553 PNMT; phenylethanolamine N-methyltransferase [EC:2.1.1.28]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K00276 AOC3; primary-amine oxidase [EC:1.4.3.21]
K00276 AOC3; primary-amine oxidase [EC:1.4.3.21]
K00276 AOC3; primary-amine oxidase [EC:1.4.3.21]
K00129 ALDH3; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 ALDH3; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 ALDH3; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K13952 ADH6; alcohol dehydrogenase 6 [EC:1.1.1.1]
K00431 TPO; thyroid peroxidase [EC:1.11.1.8]
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K01557 FAHD1; acylpyruvate hydrolase [EC:3.7.1.5]
K07253 MIF; phenylpyruvate tautomerase [EC:5.3.2.1]





     00360 Phenylalanine metabolism [PATH:lav00360]





     00380 Tryptophan metabolism [PATH:lav00380]





     00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:lav00400]





 







   09106 Metabolism of other amino acids





 







   09107 Glycan biosynthesis and metabolism





 







   09108 Metabolism of cofactors and vitamins





 







   09109 Metabolism of terpenoids and polyketides





 







   09110 Biosynthesis of other secondary metabolites





 







   09111 Xenobiotics biodegradation and metabolism





 







   09112 Not included in regular maps





 







 09120 Genetic Information Processing





 







 09130 Environmental Information Processing





 







 09140 Cellular Processes





 







 09150 Organismal Systems





 







   09151 Immune system





 







   09152 Endocrine system





     04911 Insulin secretion [PATH:lav04911]





     04910 Insulin signaling pathway [PATH:lav04910]





     04922 Glucagon signaling pathway [PATH:lav04922]





     04923 Regulation of lipolysis in adipocytes [PATH:lav04923]





     04920 Adipocytokine signaling pathway [PATH:lav04920]





     03320 PPAR signaling pathway [PATH:lav03320]





     04929 GnRH secretion [PATH:lav04929]





     04912 GnRH signaling pathway [PATH:lav04912]





     04913 Ovarian steroidogenesis [PATH:lav04913]





     04915 Estrogen signaling pathway [PATH:lav04915]





     04914 Progesterone-mediated oocyte maturation [PATH:lav04914]





     04917 Prolactin signaling pathway [PATH:lav04917]





     04921 Oxytocin signaling pathway [PATH:lav04921]





     04926 Relaxin signaling pathway [PATH:lav04926]





     04935 Growth hormone synthesis, secretion and action [PATH:lav04935]





     04918 Thyroid hormone synthesis [PATH:lav04918]





     04919 Thyroid hormone signaling pathway [PATH:lav04919]





     04928 Parathyroid hormone synthesis, secretion and action [PATH:lav04928]





     04916 Melanogenesis [PATH:lav04916]





       100669102 POMC; LOW QUALITY PROTEIN: pro-opiomelanocortin
       100664659 ASIP; agouti-signaling protein
       100655206 guanine nucleotide-binding protein G(s) subunit alpha isoform X1
       100669226 neuroendocrine secretory protein 55-like
       100671072 ADCY1; adenylate cyclase type 1
       100673570 ADCY2; LOW QUALITY PROTEIN: adenylate cyclase type 2
       100674724 ADCY3; adenylate cyclase type 3
       100675525 ADCY4; adenylate cyclase type 4
       100670244 ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5
       100653532 ADCY6; adenylate cyclase type 6 isoform X1
       100653771 ADCY7; adenylate cyclase type 7 isoform X1
       100661616 ADCY8; adenylate cyclase type 8
       100663448 ADCY9; LOW QUALITY PROTEIN: adenylate cyclase type 9
       100656966 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1
       100674245 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha
       100675162 CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1
       100653565 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1
       100673694 CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4
       100666211 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2
       100670574 CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3
       100677344 CREB3; cyclic AMP-responsive element-binding protein 3 isoform X1
       100661096 EP300; LOW QUALITY PROTEIN: histone acetyltransferase p300
       100663731 LOW QUALITY PROTEIN: CREB-binding protein
       100668533 MITF; microphthalmia-associated transcription factor isoform X1
       100653551 WNT2B; protein Wnt-2b
       100657046 WNT2; protein Wnt-2
       100663058 WNT3; proto-oncogene Wnt-3
       100662337 WNT3A; protein Wnt-3a
       100664388 WNT4; LOW QUALITY PROTEIN: protein Wnt-4
       100664544 WNT5B; protein Wnt-5b isoform X2
       100658849 WNT5A; protein Wnt-5a isoform X1
       100675069 WNT6; protein Wnt-6
       100675463 WNT7A; protein Wnt-7a
       100660629 WNT7B; protein Wnt-7b
       100665788 WNT8B; protein Wnt-8b
       100668409 WNT8A; protein Wnt-8a
       100658979 WNT9B; protein Wnt-9b
       100662057 WNT9A; protein Wnt-9a
       100674782 WNT10A; protein Wnt-10a
       100655805 WNT10B; protein Wnt-10b
       100656630 WNT11; protein Wnt-11
       100659037 WNT16; protein Wnt-16
       100657335 FZD1; frizzled-1
       100658936 FZD7; frizzled-7
       100654997 FZD2; frizzled-2
       100666465 FZD3; frizzled-3
       100675317 FZD4; frizzled-4
       100674586 FZD5; frizzled-5
       100666499 FZD8; LOW QUALITY PROTEIN: frizzled-8
       100677440 FZD6; frizzled-6
       100660631 FZD10; frizzled-10
       100658419 GNAO1; guanine nucleotide-binding protein G(o) subunit alpha
       100656672 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha isoform X1
       100673586 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1
       100657749 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1
       100657649 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
       100675105 GSK3B; glycogen synthase kinase-3 beta isoform X2
       100670988 CTNNB1; LOW QUALITY PROTEIN: catenin beta-1
       100663559 TCF7; transcription factor 7 isoform X3
       100656106 TCF7L2; transcription factor 7-like 2 isoform X22
       100658960 LEF1; lymphoid enhancer-binding factor 1 isoform X2
       100654759 KITLG; kit ligand isoform X1
       100655943 KIT; mast/stem cell growth factor receptor Kit isoform X2
       100661512 KRAS; GTPase KRas isoform X2
       100659051 NRAS; GTPase NRas
       100655727 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       100667623 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       100657587 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       100658240 MAPK3; mitogen-activated protein kinase 3
       100665157 MAPK1; mitogen-activated protein kinase 1
       100676924 TYR; tyrosinase
       100670218 TYRP1; 5,6-dihydroxyindole-2-carboxylic acid oxidase
       100656003 DCT; L-dopachrome tautomerase
       100672459 EDN1; endothelin-1 isoform X1
       100654118 EDNRB; endothelin receptor type B isoform X1
       100666344 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1
       100670234 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2
       100667957 GNAI3; LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(k) subunit alpha
       100670617 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3
       100672435 PLCB1; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
       100668575 PLCB2; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
       100663829 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
       100663507 CALM1; calmodulin-1
       100664679 CALM2; calmodulin-2
       100657612 calmodulin
       100669885 CALML4; calmodulin-like protein 4 isoform X1
       100658962 CALML3; calmodulin-like protein 3
       100658208 calmodulin
       104846071 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha
       100653927 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1
       100663321 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X2
       100658516 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta
       100665537 PRKCA; protein kinase C alpha type isoform X1
       100672078 PRKCB; LOW QUALITY PROTEIN: protein kinase C beta type
       100671733 PRKCG; LOW QUALITY PROTEIN: protein kinase C gamma type



K05228 POMC; proopiomelanocortin
K08725 ASIP; agouti signaling protein
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K09455 MITF; microphthalmia-associated transcription factor
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02620 TCF7; transcription factor 7
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00505 TYR; tyrosinase [EC:1.14.18.1]
K00506 TYRP1; tyrosinase-related protein 1 [EC:1.14.18.-]
K01827 DCT; dopachrome tautomerase [EC:5.3.3.12]
K16366 EDN1; endothelin-1
K04198 EDNRB; endothelin receptor type B
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]





     04924 Renin secretion [PATH:lav04924]





     04614 Renin-angiotensin system [PATH:lav04614]





     04925 Aldosterone synthesis and secretion [PATH:lav04925]





     04927 Cortisol synthesis and secretion [PATH:lav04927]





 







   09153 Circulatory system





 







   09154 Digestive system





 







   09155 Excretory system





 







   09156 Nervous system





 







   09157 Sensory system





 







   09158 Development and regeneration





 







   09149 Aging





 







   09159 Environmental adaptation





 







 09160 Human Diseases





 







 09180 Brite Hierarchies





 







 09190 Not Included in Pathway or Brite













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Last updated: April 25, 2024