KEGG Orthology (KO) - Latimeria chalumnae (coelacanth)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:lcm04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:lcm04012]
       102348800 pro-epidermal growth factor-like
       102356822 EGF; epidermal growth factor
       102367184 TGFA; transforming growth factor alpha
       106706150 amphiregulin-like
       102355882 AREG; amphiregulin
       102348821 ERBB2; erb-b2 receptor tyrosine kinase 2
       102362442 PLCG1; phospholipase C gamma 1
       102352804 1-phosphatidylinositol 4
       102358132 PLCG2; phospholipase C gamma 2
       102360263 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta
       102361646 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       102346458 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       102360076 calcium/calmodulin-dependent protein kinase type II subunit delta
       102361415 PRKCA; protein kinase C alpha
       102364971 PRKCB; protein kinase C beta
       102352260 PRKCG; protein kinase C gamma
       102349292 CBLC; Cbl proto-oncogene C
       102345712 CBL; Cbl proto-oncogene
       102346401 CBLB; Cbl proto-oncogene B
       102350580 STAT6; signal transducer and activator of transcription 6
       102348150 STAT5B; signal transducer and activator of transcription 5B
       102360542 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
       102356941 PTK2; protein tyrosine kinase 2
       102345797 crk-like protein
       102350481 CRK; CRK proto-oncogene, adaptor protein
       102352845 crk-like protein
       102364341 crk-like protein
       102355014 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       102352150 ABL2; ABL proto-oncogene 2, non-receptor tyrosine kinase
       102363552 NCK1; NCK adaptor protein 1
       102359773 NCK2; NCK adaptor protein 2
       102349047 PAK1; p21 (RAC1) activated kinase 1
       102367003 PAK2; p21 (RAC1) activated kinase 2
       102367518 PAK3; p21 (RAC1) activated kinase 3
       102367182 PAK4; p21 (RAC1) activated kinase 4
       102347021 PAK5; p21 (RAC1) activated kinase 5
       102355098 serine/threonine-protein kinase PAK 6-like
       102352547 MAP2K4; mitogen-activated protein kinase kinase 4
       102365163 MAP2K7; mitogen-activated protein kinase kinase 7
       102357573 MAPK8; mitogen-activated protein kinase 8
       102351693 MAPK9; mitogen-activated protein kinase 9
       102351958 MAPK10; mitogen-activated protein kinase 10
       102350279 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       102358101 transcription factor AP-1-like
       102363355 ETS domain-containing protein Elk-1-like
       102351917 ELK1; ELK1, ETS transcription factor
       102352450 BTC; betacellulin
       102353749 HBEGF; heparin binding EGF like growth factor
       102355423 EREG; epiregulin
       102353616 ERBB3; erb-b2 receptor tyrosine kinase 3
       102365318 NRG2; neuregulin 2
       102360220 ERBB4; erb-b2 receptor tyrosine kinase 4
       102356771 SHC1; SHC adaptor protein 1
       102355047 SHC2; SHC adaptor protein 2
       102362793 SHC3; SHC adaptor protein 3
       102354432 SHC4; SHC adaptor protein 4
       102353904 GRB2; growth factor receptor bound protein 2
       102347108 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       102348404 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       102355427 HRAS; HRas proto-oncogene, GTPase
       102352473 KRAS; KRAS proto-oncogene, GTPase
       102357700 GTPase HRas-like
       102361045 NRAS; neuroblastoma RAS viral oncogene homolog
       102351967 serine/threonine-protein kinase A-Raf-like
       102365161 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       102357545 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       102358560 MAP2K1; mitogen-activated protein kinase kinase 1
       102350370 MAP2K2; mitogen-activated protein kinase kinase 2
       102355992 MAPK1; mitogen-activated protein kinase 1
       102354262 mitogen-activated protein kinase 3
       102359985 transcriptional regulator Myc-2-like
       102357079 MYC; v-myc avian myelocytomatosis viral oncogene homolog
       102356417 GAB1; GRB2 associated binding protein 1
       102345605 pro-neuregulin-3
       102346205 NRG4; neuregulin 4
       102351622 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       102350948 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       102351332 phosphatidylinositol 4
       102359335 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       102353218 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       102348007 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       102359797 AKT1; AKT serine/threonine kinase 1
       102359272 AKT2; AKT serine/threonine kinase 2
       102346546 AKT3; AKT serine/threonine kinase 3
       102360124 MTOR; mechanistic target of rapamycin
       102353676 RPS6KB1; ribosomal protein S6 kinase B1
       102361574 ribosomal protein S6 kinase beta-1-like
       102357265 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       102363793 BAD; BCL2 associated agonist of cell death
       102350787 GSK3B; glycogen synthase kinase 3 beta
       102355060 CDKN1B; cyclin dependent kinase inhibitor 1B
       102361382 CDKN1A; cyclin dependent kinase inhibitor 1A
K04357 EGF; epidermal growth factor
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09782 AREG; amphiregulin
K09782 AREG; amphiregulin
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K11224 STAT5B; signal transducer and activator of transcription 5B
K11224 STAT5B; signal transducer and activator of transcription 5B
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K07365 NCK1; NCK adaptor protein 1
K19862 NCK2; NCK adaptor protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04448 JUN; transcription factor AP-1
K04375 ELK1; ETS domain-containing protein Elk-1
K04375 ELK1; ETS domain-containing protein Elk-1
K09783 BTC; betacellulin
K08523 HBEGF; heparin-binding EGF-like growth factor
K09784 EREG; epiregulin
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05456 NRG2; neuregulin 2
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K04377 MYC; Myc proto-oncogene protein
K09593 GAB1; GRB2-associated-binding protein 1
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04310 Wnt signaling pathway [PATH:lcm04310]
     04330 Notch signaling pathway [PATH:lcm04330]
     04340 Hedgehog signaling pathway [PATH:lcm04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:lcm04350]
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species
     04370 VEGF signaling pathway [PATH:lcm04370]
     04371 Apelin signaling pathway [PATH:lcm04371]
     04630 JAK-STAT signaling pathway
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway [PATH:lcm04068]
       102364242 TGFB1; transforming growth factor beta 1
       102352268 transforming growth factor beta-2-like
       102358422 TGFB2; transforming growth factor beta 2
       102358543 TGFB3; transforming growth factor beta 3
       102350402 TGFBR1; transforming growth factor beta receptor 1
       102346621 TGFBR2; transforming growth factor beta receptor 2
       102356233 TGF-beta receptor type-2-like
       102358988 mothers against decapentaplegic homolog 4-like
       102353847 SMAD4; SMAD family member 4
       102356317 SMAD3; SMAD family member 3
       102364462 STK11; serine/threonine kinase 11
       102365637 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
       102349521 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
       102350587 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
       102345693 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
       102348610 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
       102345950 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
       102366003 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
       102352356 NLK; nemo like kinase
       102353948 serine/threonine-protein kinase NLK2
       102356499 SKP2; S-phase kinase associated protein 2
       102353921 MDM2; MDM2 proto-oncogene
       102350182 SETD7; SET domain containing lysine methyltransferase 7
       102363820 CREBBP; CREB binding protein
       102352539 histone acetyltransferase p300-like
       102348704 SIRT1; sirtuin 1
       102352615 USP7; ubiquitin specific peptidase 7
       102365328 SLC2A4; solute carrier family 2 member 4
       102357573 MAPK8; mitogen-activated protein kinase 8
       102351693 MAPK9; mitogen-activated protein kinase 9
       102351958 MAPK10; mitogen-activated protein kinase 10
       102354634 STK4; serine/threonine kinase 4
       102365620 insulin-like growth factor I
       102361051 IGF1; insulin like growth factor 1
       102367342 IGF1R; insulin like growth factor 1 receptor
       102348278 INS; insulin
       102366510 IRS1; insulin receptor substrate 1
       102367331 insulin receptor substrate 1-B-like
       102364884 IRS2; insulin receptor substrate 2
       102366705 IRS4; insulin receptor substrate 4
       102351622 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       102350948 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       102351332 phosphatidylinositol 4
       102359335 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       102353218 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       102348007 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       102346160 PDPK1; 3-phosphoinositide dependent protein kinase 1
       102361819 CHUK; conserved helix-loop-helix ubiquitous kinase
       102358966 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       102348548 PTEN; phosphatase and tensin homolog
       102359797 AKT1; AKT serine/threonine kinase 1
       102359272 AKT2; AKT serine/threonine kinase 2
       102346546 AKT3; AKT serine/threonine kinase 3
       102356269 serine/threonine-protein kinase Sgk1-like
       102364173 serine/threonine-protein kinase Sgk1-like
       102363200 SGK2; SGK2, serine/threonine kinase 2
       102345438 SGK3; serine/threonine-protein kinase Sgk3
       102347273 FOXO1; forkhead box O1
       102359675 FOXO3; forkhead box O3
       102357644 FOXO4; forkhead box O4
       102349981 FOXO6; forkhead box O6
       102359097 GRM1; glutamate metabotropic receptor 1
       102350323 HOMER2; homer scaffolding protein 2
       102363688 HOMER3; homer scaffolding protein 3
       102367322 HOMER1; homer scaffolding protein 1
       102347384 AGAP2; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
       102354380 CSNK1E; casein kinase 1 epsilon
       102347088 IL6; interleukin 6
       102366797 IL10; interleukin 10
       102365345 STAT3; signal transducer and activator of transcription 3
       102348800 pro-epidermal growth factor-like
       102356822 EGF; epidermal growth factor
       102353904 GRB2; growth factor receptor bound protein 2
       102347108 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       102348404 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       102355427 HRAS; HRas proto-oncogene, GTPase
       102352473 KRAS; KRAS proto-oncogene, GTPase
       102357700 GTPase HRas-like
       102361045 NRAS; neuroblastoma RAS viral oncogene homolog
       102365161 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       102357545 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       102351967 serine/threonine-protein kinase A-Raf-like
       102358560 MAP2K1; mitogen-activated protein kinase kinase 1
       102350370 MAP2K2; mitogen-activated protein kinase kinase 2
       102355992 MAPK1; mitogen-activated protein kinase 1
       102354262 mitogen-activated protein kinase 3
       102354316 MAPK11; mitogen-activated protein kinase 11
       102354774 MAPK12; mitogen-activated protein kinase 12
       102358042 MAPK14; mitogen-activated protein kinase 14
       102366560 CDK2; cyclin dependent kinase 2
       102367189 cyclin-dependent kinase 2-like
       102359562 PRMT1; protein arginine methyltransferase 1
       102360373 forkhead box protein G1-like
       102357614 forkhead box protein G1-like
       102345768 FOXG1; forkhead box G1
       102360112 G2/mitotic-specific cyclin-B1-like
       102359547 CCNB1; cyclin B1
       102349107 CCNB2; cyclin B2
       102349356 CCNB3; cyclin B3
       102361167 CCND1; cyclin D1
       102367471 G1/S-specific cyclin-D1-like
       102351286 CCND2; cyclin D2
       102345953 G1/S-specific cyclin-D2-like
       102365710 CCNG2; cyclin G2
       102356560 CDKN2B; cyclin-dependent kinase 4 inhibitor B
       102345210 CDKN2D; cyclin dependent kinase inhibitor 2D
       102361382 CDKN1A; cyclin dependent kinase inhibitor 1A
       102355060 CDKN1B; cyclin dependent kinase inhibitor 1B
       102352332 RBL2; RB transcriptional corepressor like 2
       102348600 PLK1; polo like kinase 1
       102363585 PLK5; polo like kinase 5
       102364369 PLK2; polo like kinase 2
       102355147 PLK3; polo like kinase 3
       102349883 PLK4; polo like kinase 4
       102353479 GADD45G; growth arrest and DNA damage inducible gamma
       102361538 GADD45B; growth arrest and DNA damage inducible beta
       102349018 GADD45A; growth arrest and DNA damage inducible alpha
       102366280 FASLG; Fas ligand
       102361141 tumor necrosis factor ligand superfamily member 6-like
       102345421 TNFSF10; tumor necrosis factor superfamily member 10
       102350689 BCL6; B-cell CLL/lymphoma 6
       102352134 BCL6B; B-cell CLL/lymphoma 6B
       102363775 BNIP3; BCL2 interacting protein 3
       102354722 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
       102348303 ATG12; autophagy related 12
       102356442 gamma-aminobutyric acid receptor-associated protein-like 1
       102357322 GABARAPL2; GABA type A receptor associated protein like 2
       102348715 GABARAPL1; GABA type A receptor associated protein like 1
       102347899 CAT; catalase
       102351325 SOD2; superoxide dismutase 2
       102347668 ATM; ATM serine/threonine kinase
       102345191 PCK1; phosphoenolpyruvate carboxykinase 1
       102354904 PCK2; phosphoenolpyruvate carboxykinase, cytosolic [GTP]
       102353877 G6PC3; glucose-6-phosphatase catalytic subunit 3
       102352326 G6PC2; glucose-6-phosphatase catalytic subunit 2
       102366630 G6PC; glucose-6-phosphatase catalytic subunit
       102355178 KLF2; Kruppel like factor 2
       102345178 sphingosine 1-phosphate receptor 1-like
       102346859 S1PR1; sphingosine 1-phosphate receptor 1
       102357176 S1PR4; sphingosine-1-phosphate receptor 4
       102354195 RAG1; recombination activating 1
       102361038 RAG2; recombination activating 2
       102359606 FBXO32; F-box protein 32
       102348086 FBXO25; F-box protein 25
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K16172 IRS1; insulin receptor substrate 1
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K07187 IRS2; insulin receptor substrate 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K04603 GRM1; metabotropic glutamate receptor 1
K15010 HOMER; homer
K15010 HOMER; homer
K15010 HOMER; homer
K17848 AGAP2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05443 IL10; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04357 EGF; epidermal growth factor
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K09385 FOXG; forkhead box protein G
K09385 FOXG; forkhead box protein G
K09385 FOXG; forkhead box protein G
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10151 CCND2; G1/S-specific cyclin-D2
K10146 CCNG2; cyclin G2
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K06623 CDKN2D; cyclin-dependent kinase inhibitor 2D
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K03781 katE; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
K10305 FBXO25_32; F-box protein 25/32
     04020 Calcium signaling pathway [PATH:lcm04020]
     04070 Phosphatidylinositol signaling system [PATH:lcm04070]
     04072 Phospholipase D signaling pathway
     04071 Sphingolipid signaling pathway
     04024 cAMP signaling pathway
     04022 cGMP-PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway [PATH:lcm04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:lcm04110]
       102361167 CCND1; cyclin D1
       102367471 G1/S-specific cyclin-D1-like
       102351286 CCND2; cyclin D2
       102345953 G1/S-specific cyclin-D2-like
       102363370 CDK4; cyclin dependent kinase 4
       102366718 cyclin-dependent kinase 6-like
       102353660 CDK6; cyclin dependent kinase 6
       102347219 retinoblastoma-associated protein-like
       102366565 RB1; RB transcriptional corepressor 1
       102362730 RBL1; RB transcriptional corepressor like 1
       102352332 RBL2; RB transcriptional corepressor like 2
       102355014 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       102364559 HDAC1; histone deacetylase 1
       102358341 E2F1; E2F transcription factor 1
       102353099 E2F2; E2F transcription factor 2
       102355481 E2F3; E2F transcription factor 3
       102349190 E2F4; transcription factor E2F4
       106704459 transcription factor E2F4-like
       102354113 E2F5; E2F transcription factor 5
       102355381 TFDP1; transcription factor Dp-1
       102349473 TFDP2; transcription factor Dp-2
       102350787 GSK3B; glycogen synthase kinase 3 beta
       102364242 TGFB1; transforming growth factor beta 1
       102352268 transforming growth factor beta-2-like
       102358422 TGFB2; transforming growth factor beta 2
       102358543 TGFB3; transforming growth factor beta 3
       102360430 SMAD2; mothers against decapentaplegic homolog 2
       102356317 SMAD3; SMAD family member 3
       102358988 mothers against decapentaplegic homolog 4-like
       102353847 SMAD4; SMAD family member 4
       102359985 transcriptional regulator Myc-2-like
       102357079 MYC; v-myc avian myelocytomatosis viral oncogene homolog
       102353114 ZBTB17; zinc finger and BTB domain containing 17
       102356560 CDKN2B; cyclin-dependent kinase 4 inhibitor B
       102367385 CDKN2C; cyclin dependent kinase inhibitor 2C
       102345210 CDKN2D; cyclin dependent kinase inhibitor 2D
       102355060 CDKN1B; cyclin dependent kinase inhibitor 1B
       102365218 cyclin-dependent kinase inhibitor 1B-like
       102360661 CDKN1C; cyclin dependent kinase inhibitor 1C
       102361382 CDKN1A; cyclin dependent kinase inhibitor 1A
       102366176 CCNE1; cyclin E1
       102363290 CCNE2; cyclin E2
       102366560 CDK2; cyclin dependent kinase 2
       102367189 cyclin-dependent kinase 2-like
       102350053 SKP1; S-phase kinase associated protein 1
       102360768 CUL1; cullin 1
       102352187 RBX1; ring-box 1
       102356499 SKP2; S-phase kinase associated protein 2
       102363965 CCNA2; cyclin A2
       102366921 CCNA1; cyclin A1
       102366031 CDC6; cell division cycle 6
       102359199 CDC45; cell division cycle 45
       102346218 CDC7; cell division cycle 7
       102356028 DBF4; DBF4 zinc finger
       102364653 CDK1; cyclin dependent kinase 1
       102360112 G2/mitotic-specific cyclin-B1-like
       102359547 CCNB1; cyclin B1
       102349107 CCNB2; cyclin B2
       102349356 CCNB3; cyclin B3
       102366036 CDC25B; cell division cycle 25B
       102356985 CDC25C; cell division cycle 25C
       106703998 14-3-3 protein beta/alpha-1-like
       102355868 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
       102345251 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
       102359202 YWHAZ; 14-3-3 protein zeta/delta
       102351704 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
       102347422 14-3-3 protein epsilon
       102352354 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
       102361947 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
       102348600 PLK1; polo like kinase 1
       102352550 WEE2; WEE1 homolog 2
       102367221 wee1-like protein kinase 1-B
       102351877 PKMYT1; protein kinase, membrane associated tyrosine/threonine 1
       102353317 CCNH; cyclin H
       102360377 cyclin-dependent kinase 7-like
       102349004 ANAPC1; anaphase promoting complex subunit 1
       102352690 ANAPC2; anaphase promoting complex subunit 2
       102358952 CDC27; cell division cycle 27
       102365164 ANAPC4; anaphase promoting complex subunit 4
       102354298 anaphase-promoting complex subunit 4-like
       102345994 ANAPC5; anaphase promoting complex subunit 5
       102356648 CDC16; cell division cycle 16
       102366421 ANAPC7; anaphase promoting complex subunit 7
       102356105 CDC23; cell division cycle 23
       102348137 ANAPC10; anaphase promoting complex subunit 10
       102356804 ANAPC11; anaphase promoting complex subunit 11
       102364023 CDC26; cell division cycle 26
       102365997 ANAPC13; anaphase promoting complex subunit 13
       102346337 CDC20; cell division cycle 20
       102364481 PTTG1; pituitary tumor-transforming 1
       102366561 ESPL1; extra spindle pole bodies like 1, separase
       102354172 SMC1A; structural maintenance of chromosomes 1A
       106703120 SMC1B; structural maintenance of chromosomes 1B
       102345584 SMC3; structural maintenance of chromosomes 3
       102365220 STAG1; stromal antigen 1
       102349458 cohesin subunit SA-2-like
       102350539 STAG2; stromal antigen 2
       102345596 RAD21L1; RAD21 cohesin complex component like 1
       102352395 RAD21; RAD21 cohesin complex component
       102357881 TTK; TTK protein kinase
       102349821 BUB1; BUB1 mitotic checkpoint serine/threonine kinase
       102356157 BUB3; BUB3, mitotic checkpoint protein
       102350418 MAD1L1; MAD1 mitotic arrest deficient like 1
       102349134 MAD2L1; MAD2 mitotic arrest deficient-like 1 (yeast)
       102362803 MAD2L2; MAD2 mitotic arrest deficient-like 2 (yeast)
       102348914 FZR1; fizzy/cell division cycle 20 related 1
       102365114 fizzy-related protein homolog
       102358691 CDC14A; cell division cycle 14A
       102360761 CDC14B; cell division cycle 14B
       102354343 ATR; ATR serine/threonine kinase
       102347668 ATM; ATM serine/threonine kinase
       102366539 TP53; tumor protein p53
       102357495 CHEK1; checkpoint kinase 1
       102362683 CHEK2; checkpoint kinase 2
       102363820 CREBBP; CREB binding protein
       102352539 histone acetyltransferase p300-like
       102352949 PRKDC; protein kinase, DNA-activated, catalytic polypeptide
       102353921 MDM2; MDM2 proto-oncogene
       102353479 GADD45G; growth arrest and DNA damage inducible gamma
       102361538 GADD45B; growth arrest and DNA damage inducible beta
       102349018 GADD45A; growth arrest and DNA damage inducible alpha
       102347218 PCNA; proliferating cell nuclear antigen
       102350994 ORC1; origin recognition complex subunit 1
       102357006 ORC2; origin recognition complex subunit 2
       102362018 ORC3; origin recognition complex subunit 3
       102354182 origin recognition complex subunit 4
       102348827 ORC5; origin recognition complex subunit 5
       102346440 ORC6; origin recognition complex subunit 6
       102350529 MCM2; minichromosome maintenance complex component 2
       102361476 MCM3; minichromosome maintenance complex component 3
       102352679 MCM4; minichromosome maintenance complex component 4
       102355068 MCM5; minichromosome maintenance complex component 5
       102360691 MCM6; minichromosome maintenance complex component 6
       102354377 MCM7; minichromosome maintenance complex component 7
K04503 CCND1; G1/S-specific cyclin-D1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10151 CCND2; G1/S-specific cyclin-D2
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04683 TFDP1; transcription factor Dp-1
K09392 TFDP2; transcription factor Dp-2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04377 MYC; Myc proto-oncogene protein
K04377 MYC; Myc proto-oncogene protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K06623 CDKN2D; cyclin-dependent kinase inhibitor 2D
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K09993 CDKN1C; cyclin-dependent kinase inhibitor 1C
K09993 CDKN1C; cyclin-dependent kinase inhibitor 1C
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; RING-box protein 1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K02213 CDC6; cell division control protein 6
K06628 CDC45; cell division control protein 45
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K06629 ASK; activator of S phase kinase
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K06634 CCNH; cyclin H
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K06636 SMC1; structural maintenance of chromosome 1
K06636 SMC1; structural maintenance of chromosome 1
K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06670 SCC1; cohesin complex subunit SCC1
K06670 SCC1; cohesin complex subunit SCC1
K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04802 PCNA; proliferating cell nuclear antigen
K02603 ORC1; origin recognition complex subunit 1
K02604 ORC2; origin recognition complex subunit 2
K02605 ORC3; origin recognition complex subunit 3
K02606 ORC4; origin recognition complex subunit 4
K02607 ORC5; origin recognition complex subunit 5
K02608 ORC6; origin recognition complex subunit 6
K02540 MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:3.6.4.12]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:3.6.4.12]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
K02210 MCM7; DNA replication licensing factor MCM7 [EC:3.6.4.12]
     04111 Cell cycle - yeast
     04112 Cell cycle - Caulobacter
     04113 Meiosis - yeast
     04114 Oocyte meiosis [PATH:lcm04114]
     04210 Apoptosis [PATH:lcm04210]
     04214 Apoptosis - fly
     04215 Apoptosis - multiple species
     04216 Ferroptosis [PATH:lcm04216]
     04217 Necroptosis [PATH:lcm04217]
     04115 p53 signaling pathway [PATH:lcm04115]
       102347668 ATM; ATM serine/threonine kinase
       102362683 CHEK2; checkpoint kinase 2
       102354343 ATR; ATR serine/threonine kinase
       102357495 CHEK1; checkpoint kinase 1
       102348269 GORAB; golgin, RAB6 interacting
       102353921 MDM2; MDM2 proto-oncogene
       102358918 MDM4; MDM4, p53 regulator
       102366539 TP53; tumor protein p53
       102361382 CDKN1A; cyclin dependent kinase inhibitor 1A
       102361167 CCND1; cyclin D1
       102367471 G1/S-specific cyclin-D1-like
       102351286 CCND2; cyclin D2
       102345953 G1/S-specific cyclin-D2-like
       102363370 CDK4; cyclin dependent kinase 4
       102366718 cyclin-dependent kinase 6-like
       102353660 CDK6; cyclin dependent kinase 6
       102366176 CCNE1; cyclin E1
       102363290 CCNE2; cyclin E2
       102366560 CDK2; cyclin dependent kinase 2
       102367189 cyclin-dependent kinase 2-like
       106702484 protein reprimo A-like
       102363451 RPRM; reprimo, TP53 dependent G2 arrest mediator candidate
       102360112 G2/mitotic-specific cyclin-B1-like
       102359547 CCNB1; cyclin B1
       102349107 CCNB2; cyclin B2
       102364653 CDK1; cyclin dependent kinase 1
       102353479 GADD45G; growth arrest and DNA damage inducible gamma
       102361538 GADD45B; growth arrest and DNA damage inducible beta
       102349018 GADD45A; growth arrest and DNA damage inducible alpha
       102347366 GTSE1; G2 and S-phase expressed 1
       102349412 FAS; Fas cell surface death receptor
       102349614 PIDD1; p53-induced death domain protein 1
       102366259 uncharacterized LOC102366259
       102366681 tumor necrosis factor receptor superfamily member 10A-like
       102361530 tumor necrosis factor receptor superfamily member 10B-like
       102355925 caspase-8-like
       102356202 caspase-8-like
       102349989 caspase-8-like
       102360597 BID; BH3-interacting domain death agonist
       102359041 apoptosis regulator BAX-like
       102352490 BAX; BCL2 associated X, apoptosis regulator
       102362452 apoptosis regulatory protein Siva-like
       102358360 SIVA1; SIVA1 apoptosis inducing factor
       102358181 BCL2L1; BCL2 like 1
       102361889 TP53I3; tumor protein p53 inducible protein 3
       102356381 EI24; EI24, autophagy associated transmembrane protein
       102352894 SHISA5; shisa family member 5
       102361707 p53 apoptosis effector related to PMP-22-like
       102361982 p53 apoptosis effector related to PMP-22-like
       102347863 ZMAT3; zinc finger matrin-type 3
       102361177 SIAH1; siah E3 ubiquitin protein ligase 1
       102363280 cytochrome c
       102345199 cytochrome c-like
       102354670 APAF1; apoptotic peptidase activating factor 1
       102362720 CASP9; caspase 9
       106705928 CASP3; caspase 3
       102358055 AIFM2; apoptosis inducing factor, mitochondria associated 2
       102347870 IGFBP3; insulin like growth factor binding protein 3
       102365620 insulin-like growth factor I
       102361051 IGF1; insulin like growth factor 1
       102360184 SERPINE1; serpin family E member 1
       102364066 CD82; CD82 molecule
       102358103 THBS1; thrombospondin 1
       102361010 RRM2; ribonucleotide reductase regulatory subunit M2
       102361950 SESN1; sestrin 1
       102356692 SESN3; sestrin-3
       102348720 SESN2; sestrin-2
       102348548 PTEN; phosphatase and tensin homolog
       102365821 TSC2; tuberous sclerosis 2
       102356275 STEAP3; STEAP3 metalloreductase
       102363850 RFWD2; ring finger and WD repeat domain 2
       102350333 RCHY1; ring finger and CHY zinc finger domain containing 1
       102346817 CCNG1; cyclin G1
       102365710 CCNG2; cyclin G2
       102359801 PPM1D; protein phosphatase, Mg2+/Mn2+ dependent 1D
       102364155 TP73; tumor protein p73
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K19748 GORAB; RAB6-interacting golgin
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10151 CCND2; G1/S-specific cyclin-D2
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K10128 RPRM; reprimo, TP53-dependent G2 arrest mediator candidate
K10128 RPRM; reprimo, TP53-dependent G2 arrest mediator candidate
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10129 GTSE1; G-2 and S-phase expressed protein 1
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K02159 BAX; apoptosis regulator BAX
K22744 SIVA1; apoptosis regulatory protein Siva
K22744 SIVA1; apoptosis regulatory protein Siva
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K10133 TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]
K10134 EI24; etoposide-induced 2.4 mRNA
K10135 SCOTIN; scotin
K10136 PERP; TP53 apoptosis effector
K10136 PERP; TP53 apoptosis effector
K10137 ZMAT3; zinc finger, matrin type 3
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K22745 AIFM2; apoptosis-inducing factor 2
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05459 IGF1; insulin-like growth factor 1
K05459 IGF1; insulin-like growth factor 1
K03982 SERPINE1; plasminogen activator inhibitor 1
K06509 KAI1; CD82 antigen
K16857 THBS1; thrombospondin 1
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K07207 TSC2; tuberous sclerosis 2
K10142 STEAP3; metalloreductase STEAP3 [EC:1.16.1.-]
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10145 CCNG1; cyclin G1
K10146 CCNG2; cyclin G2
K10147 PPM1D; protein phosphatase 1D [EC:3.1.3.16]
K10148 TP73; tumor protein p73
     04218 Cellular senescence [PATH:lcm04218]
       102364242 TGFB1; transforming growth factor beta 1
       102352268 transforming growth factor beta-2-like
       102358422 TGFB2; transforming growth factor beta 2
       102358543 TGFB3; transforming growth factor beta 3
       102350402 TGFBR1; transforming growth factor beta receptor 1
       102346621 TGFBR2; transforming growth factor beta receptor 2
       102356233 TGF-beta receptor type-2-like
       102360430 SMAD2; mothers against decapentaplegic homolog 2
       102356317 SMAD3; SMAD family member 3
       102356560 CDKN2B; cyclin-dependent kinase 4 inhibitor B
       102363370 CDK4; cyclin dependent kinase 4
       102366718 cyclin-dependent kinase 6-like
       102353660 CDK6; cyclin dependent kinase 6
       102361167 CCND1; cyclin D1
       102367471 G1/S-specific cyclin-D1-like
       102351286 CCND2; cyclin D2
       102345953 G1/S-specific cyclin-D2-like
       102347219 retinoblastoma-associated protein-like
       102366565 RB1; RB transcriptional corepressor 1
       102362730 RBL1; RB transcriptional corepressor like 1
       102352332 RBL2; RB transcriptional corepressor like 2
       102358341 E2F1; E2F transcription factor 1
       102353099 E2F2; E2F transcription factor 2
       102355481 E2F3; E2F transcription factor 3
       102349190 E2F4; transcription factor E2F4
       106704459 transcription factor E2F4-like
       102354113 E2F5; E2F transcription factor 5
       102351622 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       102350948 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       102351332 phosphatidylinositol 4
       102359335 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       102353218 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       102348007 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       102347273 FOXO1; forkhead box O1
       102359675 FOXO3; forkhead box O3
       102361382 CDKN1A; cyclin dependent kinase inhibitor 1A
       102366560 CDK2; cyclin dependent kinase 2
       102367189 cyclin-dependent kinase 2-like
       102366176 CCNE1; cyclin E1
       102363290 CCNE2; cyclin E2
       102360671 Lach-UA-02; uncharacterized LOC102360671
       102356482 major histocompatibility complex class I-related gene protein-like
       102360930 class I histocompatibility antigen
       102358245 Lach-UA-01; class I histocompatibility antigen, F10 alpha chain-like
       102345632 Lach-UB-03; uncharacterized LOC102345632
       102345904 Lach-UB-05; class I histocompatibility antigen, F10 alpha chain
       106706643 Lach-UB-05; major histocompatibility complex class I-related gene protein-like
       102351815 Lach-UB-02; major histocompatibility complex class I-related gene protein
       102348567 Lach-UC-01; major histocompatibility complex class I-related gene protein-like
       102348044 class I histocompatibility antigen
       102354307 major histocompatibility complex class I-related gene protein-like
       102356466 class I histocompatibility antigen
       102365873 major histocompatibility complex class I-related gene protein-like
       102345098 Lach-UX-02; class I histocompatibility antigen, F10 alpha chain-like
       102365812 major histocompatibility complex class I-related gene protein-like
       102365553 Lach-UD-01; major histocompatibility complex class I-related gene protein-like
       102352473 KRAS; KRAS proto-oncogene, GTPase
       102357700 GTPase HRas-like
       102361045 NRAS; neuroblastoma RAS viral oncogene homolog
       102358831 RRAS2; related RAS viral (r-ras) oncogene homolog 2
       102349532 RRAS; related RAS viral (r-ras) oncogene homolog
       102359118 MRAS; muscle RAS oncogene homolog
       102356108 ras-related protein M-Ras-like
       102355427 HRAS; HRas proto-oncogene, GTPase
       102359797 AKT1; AKT serine/threonine kinase 1
       102359272 AKT2; AKT serine/threonine kinase 2
       102346546 AKT3; AKT serine/threonine kinase 3
       102358393 TSC1; tuberous sclerosis 1
       102365821 TSC2; tuberous sclerosis 2
       102353752 RHEBL1; Ras homolog enriched in brain like 1
       102345677 RHEB; Ras homolog enriched in brain
       102360124 MTOR; mechanistic target of rapamycin
       102348548 PTEN; phosphatase and tensin homolog
       102348704 SIRT1; sirtuin 1
       102363965 CCNA2; cyclin A2
       102366921 CCNA1; cyclin A1
       102351447 MYBL2; MYB proto-oncogene like 2
       102351028 LIN9; lin-9 DREAM MuvB core complex component
       102365437 LIN52; lin-52 DREAM MuvB core complex component
       102348852 LIN54; lin-54 DREAM MuvB core complex component
       102355927 RBBP4; RB binding protein 4, chromatin remodeling factor
       102356605 FOXM1; forkhead box M1
       102359985 transcriptional regulator Myc-2-like
       102357079 MYC; v-myc avian myelocytomatosis viral oncogene homolog
       102353921 MDM2; MDM2 proto-oncogene
       102366539 TP53; tumor protein p53
       102367332 RASSF5; Ras association domain family member 5
       102363698 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
       102350584 FBXW11; F-box and WD repeat domain containing 11
       102367633 HIPK1; homeodomain interacting protein kinase 1
       102350851 HIPK2; homeodomain interacting protein kinase 2
       102359392 HIPK4; homeodomain interacting protein kinase 4
       102357860 HIPK3; homeodomain interacting protein kinase 3
       102361180 PPP1CA; protein phosphatase 1 catalytic subunit alpha
       102359594 serine/threonine-protein phosphatase PP1-beta catalytic subunit-like
       102359947 PPP1CB; protein phosphatase 1 catalytic subunit beta
       102362859 PPP1CC; protein phosphatase 1 catalytic subunit gamma
       102361284 serine/threonine-protein phosphatase PP1-gamma catalytic subunit B-like
       102357545 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       102358560 MAP2K1; mitogen-activated protein kinase kinase 1
       102350370 MAP2K2; mitogen-activated protein kinase kinase 2
       102355992 MAPK1; mitogen-activated protein kinase 1
       102354262 mitogen-activated protein kinase 3
       102352546 ETS1; ETS proto-oncogene 1, transcription factor
       102351267 MAP2K3; dual specificity mitogen-activated protein kinase kinase 3
       102362389 MAP2K6; mitogen-activated protein kinase kinase 6
       102354316 MAPK11; mitogen-activated protein kinase 11
       102354774 MAPK12; mitogen-activated protein kinase 12
       102358042 MAPK14; mitogen-activated protein kinase 14
       102353479 GADD45G; growth arrest and DNA damage inducible gamma
       102361538 GADD45B; growth arrest and DNA damage inducible beta
       102349018 GADD45A; growth arrest and DNA damage inducible alpha
       102364653 CDK1; cyclin dependent kinase 1
       102360112 G2/mitotic-specific cyclin-B1-like
       102359547 CCNB1; cyclin B1
       102349107 CCNB2; cyclin B2
       102349356 CCNB3; cyclin B3
       102358712 MRE11; MRE11 homolog, double strand break repair nuclease
       102346081 RAD50; RAD50 double strand break repair protein
       102355701 NBN; nibrin
       102347668 ATM; ATM serine/threonine kinase
       102362683 CHEK2; checkpoint kinase 2
       102361438 RAD9A; RAD9 checkpoint clamp component A
       102346815 RAD9B; RAD9 checkpoint clamp component B
       102357110 RAD1; RAD1 checkpoint DNA exonuclease
       102352975 HUS1; HUS1 checkpoint clamp component
       102354343 ATR; ATR serine/threonine kinase
       102357495 CHEK1; checkpoint kinase 1
       102359142 SQSTM1; sequestosome 1
       102351802 GATA4; GATA binding protein 4
       102358239 adapter protein CIKS-like
       102354220 TRAF3IP2; TRAF3 interacting protein 2
       102356725 NFKB1; nuclear factor kappa B subunit 1
       102347088 IL6; interleukin 6
       102363632 interleukin-8-like
       106706701 interleukin-8-like
       102363090 interleukin-8-like
       102362822 interleukin-8-like
       102363372 interleukin-8-like
       102347870 IGFBP3; insulin like growth factor binding protein 3
       102360184 SERPINE1; serpin family E member 1
       102357265 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       102362783 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2
       102355269 ZFP36L1; ZFP36 ring finger protein like 1
       102366706 ZFP36L2; ZFP36 ring finger protein like 2
       102352903 zinc finger protein 36
       102360815 CACNA1D; calcium voltage-gated channel subunit alpha1 D
       102362597 TRPV4; transient receptor potential cation channel subfamily V member 4
       102357315 TRPM7; transient receptor potential cation channel subfamily M member 7
       102347136 CAPN1; calpain 1
       102363773 CAPN11; calpain 11
       102347065 CAPN2; calpain-2 catalytic subunit
       102345989 parvalbumin beta-like
       102366907 CALML6; calmodulin like 6
       102360791 calmodulin
       102347246 CALM1; calmodulin 1
       102359711 CALM2; calmodulin 2
       102361286 calmodulin
       102359693 CALML4; calmodulin like 4
       102352270 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like
       102361410 PPP3CC; protein phosphatase 3 catalytic subunit gamma
       102346544 serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
       102363964 PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
       102353071 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like
       102367157 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
       102350112 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
       102349968 nuclear factor of activated T-cells
       102352958 NFATC2; nuclear factor of activated T-cells 2
       102356282 NFATC3; nuclear factor of activated T-cells 3
       102352427 NFATC4; nuclear factor of activated T-cells 4
       102361301 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
       102359880 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
       102349825 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
       102350158 SLC25A31; solute carrier family 25 member 31
       102347011 SLC25A5; solute carrier family 25 member 5
       102349731 ADP/ATP translocase 2-like
       102356552 SLC25A4; solute carrier family 25 member 4
       102351959 PPID; peptidylprolyl isomerase D
       102350599 VDAC1; voltage dependent anion channel 1
       102366723 VDAC2; voltage dependent anion channel 2
       102358420 VDAC3; voltage dependent anion channel 3
       102366118 MCU; mitochondrial calcium uniporter
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10151 CCND2; G1/S-specific cyclin-D2
K06618 RB1; retinoblastoma-associated protein
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07830 RRAS2; Ras-related protein R-Ras2
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K07831 MRAS; Ras-related protein M-Ras
K02833 HRAS; GTPase HRas
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K21769 MYBL2; myb-related protein B
K21773 LIN9; protein lin-9
K21775 LIN52; protein lin-52
K21776 LIN54; protein lin-54
K10752 RBBP4; histone-binding protein RBBP4
K09406 FOXM; forkhead box protein M
K04377 MYC; Myc proto-oncogene protein
K04377 MYC; Myc proto-oncogene protein
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K08015 RASSF5; Ras association domain-containing protein 5
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1; C-ets-1
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K10903 HUS1; HUS1 checkpoint protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K14381 SQSTM1; sequestosome 1
K09183 GATA4; GATA-binding protein 4
K21124 TRAF3IP2; adaptor protein CIKS
K21124 TRAF3IP2; adaptor protein CIKS
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K03982 SERPINE1; plasminogen activator inhibitor 1
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K18753 ZFP36L; butyrate response factor
K18753 ZFP36L; butyrate response factor
K18753 ZFP36L; butyrate response factor
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: November 27, 2020