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KO |
 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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 02020 Two-component system
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04010 MAPK signaling pathway [PATH:mcc04010]
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04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
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04011 MAPK signaling pathway - yeast
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04012 ErbB signaling pathway [PATH:mcc04012]
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04014 Ras signaling pathway [PATH:mcc04014]
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04015 Rap1 signaling pathway [PATH:mcc04015]
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704404 RAP1A; ras-related protein Rap-1A
718171 RAP1B; ras-related protein Rap-1b
693750 LOW QUALITY PROTEIN: ras-related protein Rap-1b
716352 MRAS; ras-related protein M-Ras
711698 RAPGEF5; rap guanine nucleotide exchange factor 5
703726 DOCK4; dedicator of cytokinesis protein 4 isoform X1
574380 GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X1
100429880 GRIN2A; glutamate receptor ionotropic, NMDA 2A isoform X1
698571 GRIN2B; glutamate receptor ionotropic, NMDA 2B isoform X1
717686 calmodulin
698552 CALM1; calmodulin-1 isoform X1
715270 CALM2; calmodulin-2
703514 CALML6; calmodulin-like protein 6 isoform X1
712159 CALML5; calmodulin-like protein 5
722513 CALML3; calmodulin-like protein 3
716584 CALM3; calmodulin-3 isoform X1
693753 CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4
706351 calmodulin-like
707370 F2R; proteinase-activated receptor 1
718843 F2RL3; proteinase-activated receptor 4
708507 P2RY1; P2Y purinoceptor 1
719782 FPR1; fMet-Leu-Phe receptor
709208 LPAR1; lysophosphatidic acid receptor 1
719844 LPAR2; lysophosphatidic acid receptor 2
710828 LPAR3; lysophosphatidic acid receptor 3
707170 LPAR4; lysophosphatidic acid receptor 4
713283 LPAR5; lysophosphatidic acid receptor 5
707865 ADORA2A; adenosine receptor A2a isoform X1
696848 ADORA2B; adenosine receptor A2b
694289 guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X2
100424899 neuroendocrine secretory protein 55
697230 ADCY1; adenylate cyclase type 1 isoform X1
695328 ADCY2; adenylate cyclase type 2
693523 ADCY3; adenylate cyclase type 3
714684 ADCY4; adenylate cyclase type 4 isoform X1
715897 ADCY5; adenylate cyclase type 5
707978 ADCY6; adenylate cyclase type 6 isoform X1
694730 ADCY7; adenylate cyclase type 7
695792 ADCY8; adenylate cyclase type 8 isoform X1
706789 ADCY9; adenylate cyclase type 9 isoform X1
703967 RAPGEF3; rap guanine nucleotide exchange factor 3 isoform X2
698148 RAPGEF4; rap guanine nucleotide exchange factor 4 isoform X1
705680 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
701951 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
718418 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3
718387 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
717764 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
707225 RASGRP3; ras guanyl-releasing protein 3
722044 RASGRP2; RAS guanyl-releasing protein 2
698619 EGF; pro-epidermal growth factor isoform X2
705970 FGF1; fibroblast growth factor 1
574136 FGF2; fibroblast growth factor 2
710739 FGF6; fibroblast growth factor 6
574345 FGF7; fibroblast growth factor 7 precursor
701584 FGF10; fibroblast growth factor 10 precursor
705612 FGF16; fibroblast growth factor 16
702727 FGF22; fibroblast growth factor 22 precursor
701847 FGF20; fibroblast growth factor 20
708918 FGF3; fibroblast growth factor 3 precursor
709016 FGF4; fibroblast growth factor 4
706659 FGF17; fibroblast growth factor 17 precursor
721324 FGF9; fibroblast growth factor 9
695896 FGF5; fibroblast growth factor 5 isoform X1
702072 FGF18; fibroblast growth factor 18
722394 FGF8; fibroblast growth factor 8
709109 FGF19; fibroblast growth factor 19
718288 FGF21; fibroblast growth factor 21
710643 FGF23; fibroblast growth factor 23 precursor
711681 NGF; beta-nerve growth factor
704534 INS; insulin
698444 IGF1; insulin-like growth factor I precursor
707725 PDGFA; platelet-derived growth factor subunit A isoform X1
703173 PDGFB; platelet-derived growth factor subunit B
704310 PDGFD; platelet-derived growth factor D isoform X2
700236 PDGFC; platelet-derived growth factor C
702532 CSF1; macrophage colony-stimulating factor 1 isoform X1
574254 KITLG; kit ligand isoform X1
574209 VEGFA; vascular endothelial growth factor A isoform 1 precursor
722115 VEGFB; vascular endothelial growth factor B isoform X2
701219 PGF; placenta growth factor isoform X2
712654 VEGFD; vascular endothelial growth factor D
699502 VEGFC; vascular endothelial growth factor C precursor
708316 HGF; hepatocyte growth factor isoform X3
697017 ANGPT1; angiopoietin-1 precursor
716811 ANGPT2; angiopoietin-2 isoform X1
715213 ANGPT4; angiopoietin-4
717399 EFNA1; ephrin-A1
717373 EFNA3; ephrin-A3 precursor
704351 EFNA5; ephrin-A5 precursor
717315 EFNA4; ephrin-A4 isoform X2
721231 EFNA2; ephrin-A2
613027 EGFR; epidermal growth factor receptor isoform X1
700126 FGFR1; fibroblast growth factor receptor 1 precursor
715949 FGFR2; fibroblast growth factor receptor 2 isoform X1
712829 FGFR3; fibroblast growth factor receptor 3 isoform X10
698494 FGFR4; fibroblast growth factor receptor 4
574304 NGFR; tumor necrosis factor receptor superfamily member 16
706009 INSR; LOW QUALITY PROTEIN: insulin receptor
708227 IGF1R; insulin-like growth factor 1 receptor precursor
697002 PDGFRA; platelet-derived growth factor receptor alpha
711353 PDGFRB; platelet-derived growth factor receptor beta
711512 CSF1R; macrophage colony-stimulating factor 1 receptor
696759 KIT; mast/stem cell growth factor receptor Kit precursor
574133 FLT1; vascular endothelial growth factor receptor 1 isoform X1
716412 FLT4; vascular endothelial growth factor receptor 3 isoform X1
698293 KDR; vascular endothelial growth factor receptor 2
704562 MET; hepatocyte growth factor receptor precursor
707455 TEK; angiopoietin-1 receptor isoform X1
692343 EPHA2; ephrin type-A receptor 2 precursor
696584 CRKL; crk-like protein
701185 CRK; adapter molecule crk isoform X1
715272 RAPGEF1; rap guanine nucleotide exchange factor 1 isoform X1
713965 BCAR1; breast cancer anti-estrogen resistance protein 1 isoform X1
704387 CDH1; cadherin-1
574265 CTNNB1; catenin beta-1
698092 MAGI1; membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X13
693359 MAGI2; membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X7
709341 MAGI3; membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X1
704717 RAPGEF2; rap guanine nucleotide exchange factor 2 isoform X13
706541 RAPGEF6; rap guanine nucleotide exchange factor 6 isoform X11
710149 uncharacterized protein LOC710149
698785 LOW QUALITY PROTEIN: uncharacterized protein LOC698785
696306 T cell receptor beta variable 3-1
697904 uncharacterized protein LOC697904
703029 immunoglobulin lambda-1 light chain-like
704656 LAT; linker for activation of T-cells family member 1 isoform X2
693951 FYB1; FYN-binding protein 1 isoform X1
700374 LCP2; lymphocyte cytosolic protein 2
697043 SKAP1; src kinase-associated phosphoprotein 1 isoform X1
697069 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
718412 PRKCA; protein kinase C alpha type
701195 PRKCB; protein kinase C beta type
720263 PRKCG; protein kinase C gamma type
709647 PRKD3; serine/threonine-protein kinase D3
716937 PRKD1; serine/threonine-protein kinase D1 isoform X1
716736 PRKD2; serine/threonine-protein kinase D2 isoform X1
694181 DRD2; D(2) dopamine receptor
574142 CNR1; cannabinoid receptor 1
699310 GNAI3; guanine nucleotide-binding protein G(k) subunit alpha
703780 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2
708940 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X1
574394 GNAO1; guanine nucleotide-binding protein G(o) subunit alpha
717830 RAP1GAP; rap1 GTPase-activating protein 1 isoform X8
694485 SIPA1L1; signal-induced proliferation-associated 1-like protein 1
715958 SIPA1; signal-induced proliferation-associated protein 1 isoform X1
100425123 SIPA1L2; signal-induced proliferation-associated 1-like protein 2 isoform X1
714601 SIPA1L3; signal-induced proliferation-associated 1-like protein 3 isoform X1
713160 ID1; DNA-binding protein inhibitor ID-1
705413 THBS1; thrombospondin-1
714436 RALGDS; ral guanine nucleotide dissociation stimulator isoform X4
710293 ral-GDS-related protein isoform X2
711158 ral-GDS-related protein-like isoform X1
114670406 ral-GDS-related protein-like isoform X1
100426259 ral-GDS-related protein-like
106992479 ral-GDS-related protein-like
106995524 ral-GDS-related protein-like isoform X1
710997 ral-GDS-related protein-like isoform X1
106995478 ral-GDS-related protein-like isoform X1
703440 RALA; ras-related protein Ral-A
695852 RALB; ras-related protein Ral-B
717755 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
696709 RAC2; ras-related C3 botulinum toxin substrate 2
719305 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1
707383 amyloid beta A4 precursor protein-binding family B member 1-interacting protein isoform X1
705008 TLN2; talin-2 isoform X1
696298 TLN1; talin-1 isoform X1
714955 ITGA2B; integrin alpha-IIb isoform X2
717379 ITGB3; integrin beta-3
704416 PFN4; profilin-4
703982 PFN3; profilin-3
710753 PFN1; profilin-1
713460 PFN2; profilin-2 isoform X1
716022 VASP; vasodilator-stimulated phosphoprotein isoform X1
700559 ENAH; protein enabled homolog isoform X1
706316 EVL; ena/VASP-like protein isoform X7
713687 ACTG1; actin, cytoplasmic 2
574285 ACTB; actin, cytoplasmic 1
705671 actin
701400 ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1
706455 RHOA; transforming protein RhoA
701057 SRC; proto-oncogene tyrosine-protein kinase Src
701179 FARP2; FERM, ARHGEF and pleckstrin domain-containing protein 2 isoform X1
707637 CDC42; cell division control protein 42 homolog
694685 VAV3; guanine nucleotide exchange factor VAV3 isoform X2
713227 VAV2; guanine nucleotide exchange factor VAV2
100424246 VAV1; proto-oncogene vav isoform X1
702288 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
706472 PARD3; partitioning defective 3 homolog isoform X1
699479 PARD6G; partitioning defective 6 homolog gamma
712004 PARD6B; partitioning defective 6 homolog beta
699351 PARD6A; partitioning defective 6 homolog alpha
710340 PRKCZ; protein kinase C zeta type isoform X1
574352 PRKCI; protein kinase C iota type isoform X1
693560 AFDN; afadin isoform X1
704212 CTNND1; catenin delta-1
702623 KRIT1; krev interaction trapped protein 1
699625 RGS14; regulator of G-protein signaling 14 isoform X1
695382 RASSF5; ras association domain-containing protein 5 isoform X1
711945 ITGAL; integrin alpha-L isoform X2
714832 ITGAM; integrin alpha-M isoform X3
710577 ITGB2; integrin beta-2 isoform X1
574312 ITGB1; integrin beta-1 isoform X1
693554 BRAF; serine/threonine-protein kinase B-raf isoform X1
694725 RAF1; RAF proto-oncogene serine/threonine-protein kinase
710415 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
721821 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
708938 MAPK3; mitogen-activated protein kinase 3 isoform X1
698569 MAPK1; mitogen-activated protein kinase 1
705195 MAP2K3; dual specificity mitogen-activated protein kinase kinase 3
693914 MAP2K6; dual specificity mitogen-activated protein kinase kinase 6
715745 MAPK12; mitogen-activated protein kinase 12 isoform X1
715794 MAPK11; mitogen-activated protein kinase 11
718976 MAPK14; mitogen-activated protein kinase 14 isoform X1
719085 MAPK13; mitogen-activated protein kinase 13 isoform X1
716098 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
709959 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
710552 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
707310 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
719367 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
698996 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
714717 AKT3; RAC-gamma serine/threonine-protein kinase
697747 AKT1; RAC-alpha serine/threonine-protein kinase
700591 AKT2; RAC-beta serine/threonine-protein kinase
701758 PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
698830 HRAS; GTPase HRas
707977 KRAS; GTPase KRas
709089 NRAS; GTPase NRas
718939 RRAS; ras-related protein R-Ras
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K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K07836 RAP1B; Ras-related protein Rap-1B
K07831 MRAS; Ras-related protein M-Ras
K08019 RAPGEF5; Rap guanine nucleotide exchange factor 5
K17697 DOCK4; dedicator of cytokinesis protein 4
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04270 P2RY1; P2Y purinoceptor 1
K04172 FPR1; formyl peptide receptor 1
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04266 ADORA2A; adenosine receptor A2a
K04267 ADORA2B; adenosine receptor A2b
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K08014 RAPGEF3; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4; Rap guanine nucleotide exchange factor 4
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12361 RASGRP2; RAS guanyl-releasing protein 2
K04357 EGF; epidermal growth factor
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K02582 NGFB; nerve growth factor, beta
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2; Eph receptor A2 [EC:2.7.10.1]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K05726 BCAR1; breast cancer anti-estrogen resistance 1
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05631 AIP3; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K05629 AIP1; atrophin-1 interacting protein 1
K06112 MAGI3; membrane-associated guanylate kinase-related
K08018 RAPGEF2; Rap guanine nucleotide exchange factor 2
K08020 RAPGEF6; Rap guanine nucleotide exchange factor 6
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K10785 TRBV; T-cell receptor beta chain V region
K10785 TRBV; T-cell receptor beta chain V region
K10785 TRBV; T-cell receptor beta chain V region
K07362 LAT; linker for activation of T cells
K17698 FYB; FYN binding protein
K07361 LCP2; lymphocyte cytosolic protein 2
K17699 SKAP1; src kinase associated phosphoprotein 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K04145 DRD2; dopamine receptor D2
K04277 CNR1; cannabinoid receptor 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K17700 RAP1GAP; RAP1 GTPase activating protein 1
K17701 SIPA1L1; signal-induced proliferation-associated 1 like protein 1
K08013 SIPA1; signal-induced proliferation-associated gene 1
K17702 SIPA1L2; signal-induced proliferation-associated 1 like protein 2
K17703 SIPA1L3; signal-induced proliferation-associated 1 like protein 3
K04680 ID1; DNA-binding protein inhibitor ID1
K16857 THBS1; thrombospondin 1
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K17704 APBB1IP; amyloid beta A4 precursor protein-binding family B member 1-interacting protein
K06271 TLN; talin
K06271 TLN; talin
K06476 ITGA2B; integrin alpha 2B
K06493 ITGB3; integrin beta 3
K05759 PFN; profilin
K05759 PFN; profilin
K05759 PFN; profilin
K05759 PFN; profilin
K06274 VASP; vasodilator-stimulated phosphoprotein
K05746 ENAH; enabled
K23487 EVL; Ena/VASP-like protein
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K12490 ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
K04513 RHOA; Ras homolog gene family, member A
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06082 FARP2; FERM, RhoGEF and pleckstrin domain protein 2
K04393 CDC42; cell division control protein 42
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K05702 AF6; afadin
K05690 CTNND1; catenin (cadherin-associated protein), delta 1
K17705 KRIT1; Krev interaction trapped protein 1
K17706 RGS14; regulator of G-protein signaling 14
K08015 RASSF5; Ras association domain-containing protein 5
K05718 ITGAL; integrin alpha L
K06461 ITGAM; integrin alpha M
K06464 ITGB2; integrin beta 2
K05719 ITGB1; integrin beta 1
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
|
04310 Wnt signaling pathway [PATH:mcc04310]
|
04330 Notch signaling pathway [PATH:mcc04330]
|
04340 Hedgehog signaling pathway [PATH:mcc04340]
|
04341 Hedgehog signaling pathway - fly
|
04350 TGF-beta signaling pathway [PATH:mcc04350]
|
04390 Hippo signaling pathway [PATH:mcc04390]
|
04391 Hippo signaling pathway - fly
|
04392 Hippo signaling pathway - multiple species [PATH:mcc04392]
|
04370 VEGF signaling pathway [PATH:mcc04370]
|
04371 Apelin signaling pathway [PATH:mcc04371]
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04630 JAK-STAT signaling pathway [PATH:mcc04630]
|
04064 NF-kappa B signaling pathway [PATH:mcc04064]
|
04668 TNF signaling pathway [PATH:mcc04668]
|
04066 HIF-1 signaling pathway [PATH:mcc04066]
|
04068 FoxO signaling pathway [PATH:mcc04068]
|
04020 Calcium signaling pathway [PATH:mcc04020]
|
04070 Phosphatidylinositol signaling system [PATH:mcc04070]
|
04072 Phospholipase D signaling pathway [PATH:mcc04072]
|
04071 Sphingolipid signaling pathway [PATH:mcc04071]
|
04024 cAMP signaling pathway [PATH:mcc04024]
|
04022 cGMP-PKG signaling pathway [PATH:mcc04022]
|
04151 PI3K-Akt signaling pathway [PATH:mcc04151]
|
04152 AMPK signaling pathway [PATH:mcc04152]
|
04150 mTOR signaling pathway [PATH:mcc04150]
|
04075 Plant hormone signal transduction
|
|
|
09133 Signaling molecules and interaction
|
|
|
09140 Cellular Processes
|
|
|
09141 Transport and catabolism
|
|
|
09143 Cell growth and death
|
|
|
09144 Cellular community - eukaryotes
|
04510 Focal adhesion [PATH:mcc04510]
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574201 COL1A1; collagen alpha-1(I) chain isoform X1
700359 COL1A2; collagen alpha-2(I) chain precursor
704851 COL2A1; collagen alpha-1(II) chain isoform X2
708287 COL4A4; collagen alpha-4(IV) chain isoform X1
700281 COL4A1; collagen alpha-1(IV) chain
703707 COL4A6; collagen alpha-6(IV) chain isoform X1
100429807 COL4A2; collagen alpha-2(IV) chain isoform X1
703814 COL4A5; collagen alpha-5(IV) chain isoform X1
712444 COL4A3; collagen alpha-3(IV) chain isoform X1
721855 COL6A1; collagen alpha-1(VI) chain
694701 COL6A3; collagen alpha-3(VI) chain isoform X4
709493 COL6A2; collagen alpha-2(VI) chain isoform X2
719319 COL6A6; collagen alpha-6(VI) chain isoform X1
693357 collagen alpha-4(VI) chain-like isoform X1
719331 COL6A5; collagen alpha-5(VI) chain
694248 COL9A2; collagen alpha-2(IX) chain isoform X2
719943 COL9A3; collagen alpha-3(IX) chain isoform X2
714809 COL9A1; collagen alpha-1(IX) chain isoform X4
722472 LAMA1; LOW QUALITY PROTEIN: laminin subunit alpha-1
715394 LAMA2; laminin subunit alpha-2 isoform X1
701313 LAMA3; laminin subunit alpha-3 isoform X1
100430603 LAMA5; laminin subunit alpha-5
696685 LAMA4; laminin subunit alpha-4 isoform X1
702111 LAMB1; laminin subunit beta-1 isoform X2
707892 LAMB2; laminin subunit beta-2 precursor
720945 LAMB3; laminin subunit beta-3 isoform X1
702225 LAMB4; laminin subunit beta-4 isoform X1
715265 LAMC1; laminin subunit gamma-1
715212 LAMC2; laminin subunit gamma-2
722430 LAMC3; laminin subunit gamma-3
702601 CHAD; chondroadherin
696372 RELN; reelin isoform X3
705413 THBS1; thrombospondin-1
574276 THBS4; thrombospondin-4
720286 COMP; cartilage oligomeric matrix protein
708165 THBS2; thrombospondin-2
717572 THBS3; thrombospondin-3 precursor
613269 FN1; fibronectin isoform X1
704930 SPP1; osteopontin precursor
708499 VTN; vitronectin
702720 TNC; tenascin isoform X1
708707 TNR; tenascin-R
708587 TNN; tenascin-N isoform X1
716998 TNXB; tenascin-X isoform X7
722019 VWF; von Willebrand factor precursor
701835 IBSP; bone sialoprotein 2
703456 ITGA1; integrin alpha-1
703572 ITGA2; integrin alpha-2 precursor
714955 ITGA2B; integrin alpha-IIb isoform X2
700962 ITGA3; integrin alpha-3 isoform X1
704745 ITGA4; integrin alpha-4
574315 ITGA5; integrin alpha-5
697643 ITGA6; integrin alpha-6 precursor
707279 ITGA7; integrin alpha-7 isoform X1
698888 ITGA8; integrin alpha-8 isoform X1
106992270 ITGA9; integrin alpha-9
100428484 ITGA10; integrin alpha-10 isoform X3
694090 ITGA11; integrin alpha-11
707756 ITGAV; integrin alpha-V precursor
574312 ITGB1; integrin beta-1 isoform X1
717379 ITGB3; integrin beta-3
703770 ITGB4; integrin beta-4 isoform X4
715710 ITGB5; integrin beta-5 precursor
700454 ITGB6; integrin beta-6 isoform X1
699405 ITGB7; integrin beta-7
707247 ITGB8; integrin beta-8 precursor
707725 PDGFA; platelet-derived growth factor subunit A isoform X1
703173 PDGFB; platelet-derived growth factor subunit B
704310 PDGFD; platelet-derived growth factor D isoform X2
700236 PDGFC; platelet-derived growth factor C
698619 EGF; pro-epidermal growth factor isoform X2
698444 IGF1; insulin-like growth factor I precursor
574209 VEGFA; vascular endothelial growth factor A isoform 1 precursor
722115 VEGFB; vascular endothelial growth factor B isoform X2
701219 PGF; placenta growth factor isoform X2
712654 VEGFD; vascular endothelial growth factor D
699502 VEGFC; vascular endothelial growth factor C precursor
708316 HGF; hepatocyte growth factor isoform X3
697002 PDGFRA; platelet-derived growth factor receptor alpha
711353 PDGFRB; platelet-derived growth factor receptor beta
708227 IGF1R; insulin-like growth factor 1 receptor precursor
698293 KDR; vascular endothelial growth factor receptor 2
613027 EGFR; epidermal growth factor receptor isoform X1
574133 FLT1; vascular endothelial growth factor receptor 1 isoform X1
716412 FLT4; vascular endothelial growth factor receptor 3 isoform X1
704562 MET; hepatocyte growth factor receptor precursor
697573 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
701057 SRC; proto-oncogene tyrosine-protein kinase Src
716936 ARHGAP35; rho GTPase-activating protein 35
100430157 ARHGAP5; rho GTPase-activating protein 5
706455 RHOA; transforming protein RhoA
700918 DIAPH1; protein diaphanous homolog 1 isoform X1
698223 ROCK1; rho-associated protein kinase 1
708444 ROCK2; rho-associated protein kinase 2
711937 MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform
697765 MYL5; myosin light chain 5 isoform X1
707293 MYL7; myosin regulatory light chain 2, atrial isoform
709784 MYL9; myosin regulatory light polypeptide 9
106997584 MYL10; myosin regulatory light chain 10 isoform X3
694957 MYL12B; myosin regulatory light chain 12B
695077 MYL12A; myosin, light chain 12A, regulatory, non-sarcomeric isoform X1
711778 MYLPF; myosin regulatory light chain 2, skeletal muscle isoform
703302 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit
709935 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit
721735 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit
695735 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
705775 PPP1R12B; protein phosphatase 1 regulatory subunit 12B isoform X6
698538 LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 12C
114674157 PPP1R12C; LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 12C
712830 MYLK2; myosin light chain kinase 2, skeletal/cardiac muscle
707361 MYLK4; myosin light chain kinase family member 4 isoform X1
715422 MYLK; myosin light chain kinase, smooth muscle isoform X1
716132 MYLK3; myosin light chain kinase 3 isoform X1
700538 PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1
710007 PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
721744 PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1
713687 ACTG1; actin, cytoplasmic 2
574285 ACTB; actin, cytoplasmic 1
705671 actin
717161 RASGRF1; ras-specific guanine nucleotide-releasing factor 1 isoform X1
703047 CAPN2; calpain-2 catalytic subunit
693666 ACTN4; alpha-actinin-4
711994 ACTN1; alpha-actinin-1 isoform X1
705008 TLN2; talin-2 isoform X1
696298 TLN1; talin-1 isoform X1
699524 FLNA; filamin-A isoform X1
702732 FLNB; filamin-B isoform X1
700223 FLNC; filamin-C isoform X1
696336 PXN; paxillin isoform X1
709944 ILK; integrin-linked protein kinase
706407 ZYX; zyxin
716022 VASP; vasodilator-stimulated phosphoprotein isoform X1
721921 VCL; vinculin isoform X1
712624 PARVG; gamma-parvin isoform X2
703481 PARVA; alpha-parvin isoform X1
715859 PARVB; beta-parvin isoform X1
697523 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X2
714717 AKT3; RAC-gamma serine/threonine-protein kinase
697747 AKT1; RAC-alpha serine/threonine-protein kinase
700591 AKT2; RAC-beta serine/threonine-protein kinase
713114 GSK3B; glycogen synthase kinase-3 beta isoform X1
574265 CTNNB1; catenin beta-1
718412 PRKCA; protein kinase C alpha type
701195 PRKCB; protein kinase C beta type
720263 PRKCG; protein kinase C gamma type
700634 PTK2; focal adhesion kinase 1 isoform X8
716098 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
709959 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
710552 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
707310 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
719367 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
698996 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
705121 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
694685 VAV3; guanine nucleotide exchange factor VAV3 isoform X2
713227 VAV2; guanine nucleotide exchange factor VAV2
100424246 VAV1; proto-oncogene vav isoform X1
717755 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
696709 RAC2; ras-related C3 botulinum toxin substrate 2
719305 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1
698585 PAK1; serine/threonine-protein kinase PAK 1 isoform X5
710314 PAK2; serine/threonine-protein kinase PAK 2
706217 PAK3; serine/threonine-protein kinase PAK 3 isoform X1
696676 PAK4; serine/threonine-protein kinase PAK 4 isoform X1
719458 PAK5; serine/threonine-protein kinase PAK 7
701589 PAK6; serine/threonine-protein kinase PAK 6
707637 CDC42; cell division control protein 42 homolog
713965 BCAR1; breast cancer anti-estrogen resistance protein 1 isoform X1
696584 CRKL; crk-like protein
701185 CRK; adapter molecule crk isoform X1
700788 DOCK1; dedicator of cytokinesis protein 1 isoform X1
715272 RAPGEF1; rap guanine nucleotide exchange factor 1 isoform X1
704404 RAP1A; ras-related protein Rap-1A
718171 RAP1B; ras-related protein Rap-1b
693750 LOW QUALITY PROTEIN: ras-related protein Rap-1b
699736 MAPK10; mitogen-activated protein kinase 10 isoform 1
711115 MAPK8; mitogen-activated protein kinase 8 isoform X1
715782 MAPK9; mitogen-activated protein kinase 9 isoform X2
716452 JUN; transcription factor AP-1
693554 BRAF; serine/threonine-protein kinase B-raf isoform X1
704449 CAV1; caveolin-1
706980 CAV2; caveolin-2
702163 CAV3; caveolin-3
574214 FYN; tyrosine-protein kinase Fyn isoform X1
718982 SHC1; SHC-transforming protein 1
721021 SHC2; SHC-transforming protein 2
574275 SHC3; SHC-transforming protein 3
714611 SHC4; SHC-transforming protein 4
702041 GRB2; growth factor receptor-bound protein 2
713777 SOS1; son of sevenless homolog 1 isoform X1
705601 SOS2; son of sevenless homolog 2
698830 HRAS; GTPase HRas
694725 RAF1; RAF proto-oncogene serine/threonine-protein kinase
710415 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
708938 MAPK3; mitogen-activated protein kinase 3 isoform X1
698569 MAPK1; mitogen-activated protein kinase 1
712610 ELK1; ETS domain-containing protein Elk-1
114672301 ETS domain-containing protein Elk-1-like isoform X1
574320 CCND1; G1/S-specific cyclin-D1
710379 CCND2; G1/S-specific cyclin-D2
695215 CCND3; G1/S-specific cyclin-D3
702592 BIRC2; baculoviral IAP repeat-containing protein 2
702468 BIRC3; baculoviral IAP repeat-containing protein 3
698057 XIAP; E3 ubiquitin-protein ligase XIAP
717740 BAD; bcl2-associated agonist of cell death
707407 BCL2; apoptosis regulator Bcl-2
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K06236 COL1A; collagen type I alpha
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K08131 COL9A; collagen type IX alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K05459 IGF1; insulin-like growth factor 1
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05732 ARHGAP35; glucocorticoid receptor DNA-binding factor 1
K13709 ARHGAP5; Rho GTPase-activating protein 5
K04513 RHOA; Ras homolog gene family, member A
K05740 DIAPH1; diaphanous 1
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
K17457 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
K17457 PPP1R12C; protein phosphatase 1 regulatory subunit 12C
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K05699 ACTN1_4; actinin alpha 1/4
K05699 ACTN1_4; actinin alpha 1/4
K06271 TLN; talin
K06271 TLN; talin
K04437 FLNA; filamin
K04437 FLNA; filamin
K04437 FLNA; filamin
K05760 PXN; paxillin
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K06273 ZYX; zyxin
K06274 VASP; vasodilator-stimulated phosphoprotein
K05700 VCL; vinculin
K06275 PARV; parvin
K06275 PARV; parvin
K06275 PARV; parvin
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04393 CDC42; cell division control protein 42
K05726 BCAR1; breast cancer anti-estrogen resistance 1
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K07836 RAP1B; Ras-related protein Rap-1B
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04375 ELK1; ETS domain-containing protein Elk-1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K02158 BAD; Bcl-2-antagonist of cell death
K02161 BCL2; apoptosis regulator Bcl-2
|
04520 Adherens junction [PATH:mcc04520]
|
04530 Tight junction [PATH:mcc04530]
|
04540 Gap junction [PATH:mcc04540]
|
04550 Signaling pathways regulating pluripotency of stem cells [PATH:mcc04550]
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09145 Cellular community - prokaryotes
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09142 Cell motility
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09150 Organismal Systems
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09151 Immune system
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09152 Endocrine system
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04911 Insulin secretion [PATH:mcc04911]
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04910 Insulin signaling pathway [PATH:mcc04910]
|
704534 INS; insulin
706009 INSR; LOW QUALITY PROTEIN: insulin receptor
707870 IRS1; insulin receptor substrate 1
698536 IRS2; insulin receptor substrate 2
703846 IRS4; insulin receptor substrate 4
707310 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
719367 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
698996 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
716098 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
709959 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
710552 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
697523 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X2
714717 AKT3; RAC-gamma serine/threonine-protein kinase
697747 AKT1; RAC-alpha serine/threonine-protein kinase
700591 AKT2; RAC-beta serine/threonine-protein kinase
713114 GSK3B; glycogen synthase kinase-3 beta isoform X1
574233 GYS1; glycogen [starch] synthase, muscle
706152 GYS2; glycogen [starch] synthase, liver isoform X1
703302 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit
709935 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit
721735 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit
701281 PPP1R3D; protein phosphatase 1 regulatory subunit 3D
697381 PPP1R3C; protein phosphatase 1 regulatory subunit 3C
699128 PPP1R3B; protein phosphatase 1 regulatory subunit 3B
703562 PPP1R3A; protein phosphatase 1 regulatory subunit 3A
713209 PPP1R3E; protein phosphatase 1 regulatory subunit 3E
715950 PPP1R3F; protein phosphatase 1 regulatory subunit 3F isoform X1
703091 PHKG1; phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
100423096 PHKG2; phosphorylase b kinase gamma catalytic chain, liver/testis isoform isoform X1
694376 PHKA2; phosphorylase b kinase regulatory subunit alpha, liver isoform isoform X1
699764 PHKA1; phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform
716390 PHKB; phosphorylase b kinase regulatory subunit beta
717686 calmodulin
698552 CALM1; calmodulin-1 isoform X1
715270 CALM2; calmodulin-2
703514 CALML6; calmodulin-like protein 6 isoform X1
712159 CALML5; calmodulin-like protein 5
722513 CALML3; calmodulin-like protein 3
716584 CALM3; calmodulin-3 isoform X1
693753 CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4
706351 calmodulin-like
706853 PYGL; glycogen phosphorylase, liver form
705777 PYGB; glycogen phosphorylase, brain form
717451 PYGM; glycogen phosphorylase, muscle form
698954 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X1
709728 PRKACB; cAMP-dependent protein kinase catalytic subunit beta
718632 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X1
700652 PRKACG; cAMP-dependent protein kinase catalytic subunit gamma
700770 PRKAR2B; cAMP-dependent protein kinase type II-beta regulatory subunit
695770 PRKAR1B; cAMP-dependent protein kinase type I-beta regulatory subunit isoform X1
708981 PRKAR2A; cAMP-dependent protein kinase type II-alpha regulatory subunit
719021 PRKAR1A; cAMP-dependent protein kinase type I-alpha regulatory subunit
707997 LIPE; hormone-sensitive lipase
710340 PRKCZ; protein kinase C zeta type isoform X1
574352 PRKCI; protein kinase C iota type isoform X1
714701 SLC2A4; solute carrier family 2, facilitated glucose transporter member 4
716527 flotillin-2 isoform X1
714175 FLOT1; flotillin-1
114669752 FLOT2; LOW QUALITY PROTEIN: flotillin-2
714861 SH2B2; SH2B adapter protein 2 isoform X3
100424331 SORBS1; sorbin and SH3 domain-containing protein 1 isoform X1
704311 CBL; E3 ubiquitin-protein ligase CBL
703879 CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1
696584 CRKL; crk-like protein
701185 CRK; adapter molecule crk isoform X1
715272 RAPGEF1; rap guanine nucleotide exchange factor 1 isoform X1
717769 RHOQ; rho-related GTP-binding protein RhoQ isoform X1
705801 EXOC7; exocyst complex component 7 isoform X2
703934 TRIP10; cdc42-interacting protein 4 isoform X2
706972 SREBF1; sterol regulatory element-binding protein 1 isoform X1
714218 ACACA; acetyl-CoA carboxylase 1 precursor
706909 ACACB; acetyl-CoA carboxylase 2 isoform X1
715708 FASN; fatty acid synthase
719152 PKLR; pyruvate kinase PKLR isoform X1
710479 HK2; hexokinase-2 isoform X1
698120 HK3; hexokinase-3 isoform X1
711922 HK1; hexokinase-1 isoform X1
711995 HKDC1; putative hexokinase HKDC1 isoform X1
699728 GCK; glucokinase isoform X1
695558 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1
717703 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2
695737 PRKAB1; 5'-AMP-activated protein kinase subunit beta-1
699806 PRKAB2; 5'-AMP-activated protein kinase subunit beta-2
702782 PRKAG3; 5'-AMP-activated protein kinase subunit gamma-3 isoform X2
709298 PRKAG1; 5'-AMP-activated protein kinase subunit gamma-1
100425255 PRKAG2; 5'-AMP-activated protein kinase subunit gamma-2 isoform X1
700030 FOXO1; forkhead box protein O1
715762 PPARGC1A; peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X3
712053 G6PC; glucose-6-phosphatase
709062 G6PC2; glucose-6-phosphatase 2
714276 G6PC3; glucose-6-phosphatase 3
709022 FBP1; fructose-1,6-bisphosphatase 1
100430821 FBP2; fructose-1,6-bisphosphatase isozyme 2
714922 PCK2; phosphoenolpyruvate carboxykinase [GTP], mitochondrial
696207 PCK1; phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X1
106992736 MTOR; serine/threonine-protein kinase mTOR
712848 RPTOR; regulatory-associated protein of mTOR isoform X1
721731 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X2
711979 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
712274 40S ribosomal protein S6
703628 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1
713487 EIF4E2; eukaryotic translation initiation factor 4E type 2
706751 EIF4E; eukaryotic translation initiation factor 4E
703732 EIF4E1B; eukaryotic translation initiation factor 4E type 1B
714645 TSC1; hamartin isoform X1
694965 TSC2; tuberin isoform X7
715378 RHEB; GTP-binding protein Rheb
717740 BAD; bcl2-associated agonist of cell death
718982 SHC1; SHC-transforming protein 1
721021 SHC2; SHC-transforming protein 2
574275 SHC3; SHC-transforming protein 3
714611 SHC4; SHC-transforming protein 4
702041 GRB2; growth factor receptor-bound protein 2
713777 SOS1; son of sevenless homolog 1 isoform X1
705601 SOS2; son of sevenless homolog 2
698830 HRAS; GTPase HRas
707977 KRAS; GTPase KRas
709089 NRAS; GTPase NRas
707169 ARAF; serine/threonine-protein kinase A-Raf
693554 BRAF; serine/threonine-protein kinase B-raf isoform X1
694725 RAF1; RAF proto-oncogene serine/threonine-protein kinase
710415 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
721821 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
708938 MAPK3; mitogen-activated protein kinase 3 isoform X1
698569 MAPK1; mitogen-activated protein kinase 1
721436 MKNK2; MAP kinase-interacting serine/threonine-protein kinase 2
710061 MKNK1; MAP kinase-interacting serine/threonine-protein kinase 1 isoform X3
712610 ELK1; ETS domain-containing protein Elk-1
114672301 ETS domain-containing protein Elk-1-like isoform X1
711180 SOCS1; suppressor of cytokine signaling 1
715772 SOCS2; suppressor of cytokine signaling 2
715680 SOCS3; suppressor of cytokine signaling 3
696146 SOCS4; suppressor of cytokine signaling 4
702016 PTPN1; tyrosine-protein phosphatase non-receptor type 1
701160 PTPRF; receptor-type tyrosine-protein phosphatase F isoform X1
699736 MAPK10; mitogen-activated protein kinase 10 isoform 1
711115 MAPK8; mitogen-activated protein kinase 8 isoform X1
715782 MAPK9; mitogen-activated protein kinase 9 isoform X2
704683 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta
718421 INPPL1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
719508 INPP5A; type I inositol 1,4,5-trisphosphate 5-phosphatase isoform X1
|
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K17453 PPP1R3F; protein phosphatase 1 regulatory subunit 3F
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K07192 FLOT; flotillin
K07192 FLOT; flotillin
K07192 FLOT; flotillin
K07193 SH2B; SH2B adapter protein 2
K06086 SORBS1; sorbin and SH3 domain containing protein 1
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K07194 RHOQ; Ras homolog gene family, member Q
K07195 EXOC7; exocyst complex component 7
K07196 TRIP10; thyroid hormone receptor interactor 10
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K12407 GCK; glucokinase [EC:2.7.1.2]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07201 FOXO1; forkhead box protein O1
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e; small subunit ribosomal protein S6e
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K02158 BAD; Bcl-2-antagonist of cell death
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04375 ELK1; ETS domain-containing protein Elk-1
K04375 ELK1; ETS domain-containing protein Elk-1
K04694 SOCS1; suppressor of cytokine signaling 1
K04695 SOCS2; suppressor of cytokine signaling 2
K04696 SOCS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K05696 PTPN1; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K05695 PTPRF; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K15909 SHIP2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K01106 INPP5A; inositol polyphosphate 5-phosphatase INPP5A [EC:3.1.3.56]
|
04922 Glucagon signaling pathway [PATH:mcc04922]
|
04923 Regulation of lipolysis in adipocytes [PATH:mcc04923]
|
04920 Adipocytokine signaling pathway [PATH:mcc04920]
|
03320 PPAR signaling pathway [PATH:mcc03320]
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04929 GnRH secretion [PATH:mcc04929]
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04912 GnRH signaling pathway [PATH:mcc04912]
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04913 Ovarian steroidogenesis [PATH:mcc04913]
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04915 Estrogen signaling pathway [PATH:mcc04915]
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04914 Progesterone-mediated oocyte maturation [PATH:mcc04914]
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04917 Prolactin signaling pathway [PATH:mcc04917]
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04921 Oxytocin signaling pathway [PATH:mcc04921]
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04926 Relaxin signaling pathway [PATH:mcc04926]
|
04935 Growth hormone synthesis, secretion and action [PATH:mcc04935]
|
04918 Thyroid hormone synthesis [PATH:mcc04918]
|
04919 Thyroid hormone signaling pathway [PATH:mcc04919]
|
04928 Parathyroid hormone synthesis, secretion and action [PATH:mcc04928]
|
04916 Melanogenesis [PATH:mcc04916]
|
04924 Renin secretion [PATH:mcc04924]
|
04614 Renin-angiotensin system [PATH:mcc04614]
|
04925 Aldosterone synthesis and secretion [PATH:mcc04925]
|
04927 Cortisol synthesis and secretion [PATH:mcc04927]
|
|
|
09153 Circulatory system
|
|
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09154 Digestive system
|
|
|
09155 Excretory system
|
|
|
09156 Nervous system
|
04724 Glutamatergic synapse [PATH:mcc04724]
|
04727 GABAergic synapse [PATH:mcc04727]
|
04725 Cholinergic synapse [PATH:mcc04725]
|
04728 Dopaminergic synapse [PATH:mcc04728]
|
04726 Serotonergic synapse [PATH:mcc04726]
|
04720 Long-term potentiation [PATH:mcc04720]
|
04730 Long-term depression [PATH:mcc04730]
|
04723 Retrograde endocannabinoid signaling [PATH:mcc04723]
|
04721 Synaptic vesicle cycle [PATH:mcc04721]
|
04722 Neurotrophin signaling pathway [PATH:mcc04722]
|
711681 NGF; beta-nerve growth factor
701245 BDNF; brain-derived neurotrophic factor isoform X1
718534 NTF4; neurotrophin-4 precursor
721988 NTF3; neurotrophin-3 isoform X1
719670 NTRK1; high affinity nerve growth factor receptor isoform X3
709757 NTRK2; BDNF/NT-3 growth factors receptor precursor
697615 NTRK3; NT-3 growth factor receptor precursor
714861 SH2B2; SH2B adapter protein 2 isoform X3
710839 SH2B3; SH2B adapter protein 3 isoform X6
708160 SH2B1; SH2B adapter protein 1 isoform X1
702041 GRB2; growth factor receptor-bound protein 2
713777 SOS1; son of sevenless homolog 1 isoform X1
705601 SOS2; son of sevenless homolog 2
698830 HRAS; GTPase HRas
707977 KRAS; GTPase KRas
709089 NRAS; GTPase NRas
694725 RAF1; RAF proto-oncogene serine/threonine-protein kinase
693554 BRAF; serine/threonine-protein kinase B-raf isoform X1
710415 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
721821 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
708938 MAPK3; mitogen-activated protein kinase 3 isoform X1
698569 MAPK1; mitogen-activated protein kinase 1
710337 RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1
716899 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1
696825 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1
714794 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1
699798 RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1
703965 ATF4; cyclic AMP-dependent transcription factor ATF-4
707407 BCL2; apoptosis regulator Bcl-2
693522 KIDINS220; kinase D-interacting substrate of 220 kDa isoform X1
717117 FRS2; fibroblast growth factor receptor substrate 2
696584 CRKL; crk-like protein
701185 CRK; adapter molecule crk isoform X1
715272 RAPGEF1; rap guanine nucleotide exchange factor 1 isoform X1
704404 RAP1A; ras-related protein Rap-1A
718171 RAP1B; ras-related protein Rap-1b
693750 LOW QUALITY PROTEIN: ras-related protein Rap-1b
717866 MAP3K3; mitogen-activated protein kinase kinase kinase 3
711672 MAP2K5; dual specificity mitogen-activated protein kinase kinase 5 isoform X4
702837 MAPK7; mitogen-activated protein kinase 7 isoform X4
715745 MAPK12; mitogen-activated protein kinase 12 isoform X1
715794 MAPK11; mitogen-activated protein kinase 11
718976 MAPK14; mitogen-activated protein kinase 14 isoform X1
719085 MAPK13; mitogen-activated protein kinase 13 isoform X1
695044 MAPKAPK2; MAP kinase-activated protein kinase 2 isoform X2
718982 SHC1; SHC-transforming protein 1
721021 SHC2; SHC-transforming protein 2
574275 SHC3; SHC-transforming protein 3
714611 SHC4; SHC-transforming protein 4
700367 GAB1; GRB2-associated-binding protein 1
707310 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
719367 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
698996 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
716098 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
709959 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
710552 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
714717 AKT3; RAC-gamma serine/threonine-protein kinase
697747 AKT1; RAC-alpha serine/threonine-protein kinase
700591 AKT2; RAC-beta serine/threonine-protein kinase
694844 NFKBIB; NF-kappa-B inhibitor beta
695335 NFKBIA; NF-kappa-B inhibitor alpha
702498 NFKBIE; LOW QUALITY PROTEIN: NF-kappa-B inhibitor epsilon
710324 NFKB1; nuclear factor NF-kappa-B p105 subunit
715919 RELA; transcription factor p65 isoform X1
700731 FOXO3; forkhead box protein O3
574159 FASLG; tumor necrosis factor ligand superfamily member 6
717740 BAD; bcl2-associated agonist of cell death
713114 GSK3B; glycogen synthase kinase-3 beta isoform X1
697523 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X2
707870 IRS1; insulin receptor substrate 1
697069 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
714173 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1
694656 PRKCD; protein kinase C delta type
717686 calmodulin
698552 CALM1; calmodulin-1 isoform X1
715270 CALM2; calmodulin-2
703514 CALML6; calmodulin-like protein 6 isoform X1
712159 CALML5; calmodulin-like protein 5
722513 CALML3; calmodulin-like protein 3
716584 CALM3; calmodulin-3 isoform X1
693753 CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4
706351 calmodulin-like
705980 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma
702504 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X2
706977 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X11
710540 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
712322 CAMK4; calcium/calmodulin-dependent protein kinase type IV isoform X1
722449 ABL1; tyrosine-protein kinase ABL1 isoform X1
712044 PTPN11; tyrosine-protein phosphatase non-receptor type 11
100430078 MATK; megakaryocyte-associated tyrosine-protein kinase isoform X1
574304 NGFR; tumor necrosis factor receptor superfamily member 16
722292 ARHGDIG; rho GDP-dissociation inhibitor 3
702320 ARHGDIB; rho GDP-dissociation inhibitor 2
714752 ARHGDIA; rho GDP-dissociation inhibitor 1
706455 RHOA; transforming protein RhoA
707637 CDC42; cell division control protein 42 homolog
717755 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
710979 MAP3K1; mitogen-activated protein kinase kinase kinase 1
711382 MAP3K5; mitogen-activated protein kinase kinase kinase 5 isoform X1
710077 MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1
699736 MAPK10; mitogen-activated protein kinase 10 isoform 1
711115 MAPK8; mitogen-activated protein kinase 8 isoform X1
715782 MAPK9; mitogen-activated protein kinase 9 isoform X2
716452 JUN; transcription factor AP-1
716170 TP53; cellular tumor antigen p53
718948 BAX; apoptosis regulator BAX
695164 TP73; tumor protein p73 isoform X1
716907 TRAF6; TNF receptor-associated factor 6
712237 ZNF274; neurotrophin receptor-interacting factor homolog isoform X3
704529 PRDM4; PR domain zinc finger protein 4
696658 MAGED1; melanoma-associated antigen D1
100428980 BEX3; protein BEX3
720156 YWHAE; 14-3-3 protein epsilon isoform X1
695567 RIPK2; receptor-interacting serine/threonine-protein kinase 2 isoform X1
699919 IRAK1; interleukin-1 receptor-associated kinase 1
698091 IRAK2; interleukin-1 receptor-associated kinase-like 2 isoform X1
717845 IRAK3; interleukin-1 receptor-associated kinase 3 isoform X1
700568 IRAK4; interleukin-1 receptor-associated kinase 4
704683 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta
698310 SORT1; sortilin isoform X1
696274 PSEN1; presenilin-1
698770 PSEN2; presenilin-2
|
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K12457 NTF4; neurotrophin 4
K04356 NTF3; neurotrophin 3
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K05101 NTRK3; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
K07193 SH2B; SH2B adapter protein 2
K12459 SH2B1_3; SH2B adaptor protein 1/3
K12459 SH2B1_3; SH2B adaptor protein 1/3
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K02161 BCL2; apoptosis regulator Bcl-2
K12460 KIDINS220; ankyrin repeat-rich membrane spanning protein
K12461 FRS2; fibroblast growth factor receptor substrate 2
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K07836 RAP1B; Ras-related protein Rap-1B
K04421 MAP3K3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04463 MAP2K5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K09593 GAB1; GRB2-associated-binding protein 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K09408 FOXO3; forkhead box protein O3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K16172 IRS1; insulin receptor substrate 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K08888 MATK; megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K12462 ARHGDI; Rho GDP-dissociation inhibitor
K12462 ARHGDI; Rho GDP-dissociation inhibitor
K12462 ARHGDI; Rho GDP-dissociation inhibitor
K04513 RHOA; Ras homolog gene family, member A
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04451 TP53; tumor protein p53
K02159 BAX; apoptosis regulator BAX
K10148 TP73; tumor protein p73
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K12458 ZNF274; zinc finger protein 274
K12463 PRDM4; PR domain zinc finger protein 4 [EC:2.1.1.-]
K12464 MAGED1; melanoma-associated antigen D1
K12465 NGFRAP1; nerve growth factor receptor-associated protein 1
K06630 YWHAE; 14-3-3 protein epsilon
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
K04732 IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K12388 SORT1; sortilin
K04505 PSEN1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2; presenilin 2 [EC:3.4.23.-]
|
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09157 Sensory system
|
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|
09158 Development and regeneration
|
|
|
09149 Aging
|
|
|
09159 Environmental adaptation
|
|
|
09160 Human Diseases
|
|
|
09161 Cancer: overview
|
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:mcc05210]
|
05212 Pancreatic cancer [PATH:mcc05212]
|
05225 Hepatocellular carcinoma [PATH:mcc05225]
|
05226 Gastric cancer [PATH:mcc05226]
|
05214 Glioma [PATH:mcc05214]
|
05216 Thyroid cancer [PATH:mcc05216]
|
05221 Acute myeloid leukemia [PATH:mcc05221]
|
05220 Chronic myeloid leukemia [PATH:mcc05220]
|
05217 Basal cell carcinoma [PATH:mcc05217]
|
05218 Melanoma [PATH:mcc05218]
|
05211 Renal cell carcinoma [PATH:mcc05211]
|
704678 HIF1A; hypoxia-inducible factor 1-alpha isoform X4
714641 EPAS1; endothelial PAS domain-containing protein 1 isoform X1
713410 EGLN1; egl nine homolog 1 isoform X1
717342 EGLN3; egl nine homolog 3
703083 EGLN2; egl nine homolog 2
114674212 EGLN2; LOW QUALITY PROTEIN: egl nine homolog 2
106996285 VHL; von Hippel-Lindau disease tumor suppressor isoform X1
698922 ELOC; transcription elongation factor B polypeptide 1
100428355 elongin-C-like
715218 elongin-B
700034 ELOB; elongin-B
710252 RBX1; E3 ubiquitin-protein ligase RBX1
698384 CUL2; cullin-2
715971 ARNT; aryl hydrocarbon receptor nuclear translocator isoform X1
712786 ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X1
706258 EP300; histone acetyltransferase p300
704331 CREBBP; CREB-binding protein
698931 SLC2A1; solute carrier family 2, facilitated glucose transporter member 1
574209 VEGFA; vascular endothelial growth factor A isoform 1 precursor
106992315 TGFB1; transforming growth factor beta-1 proprotein isoform X2
707540 TGFB2; transforming growth factor beta-2 precursor
703239 TGFB3; transforming growth factor beta-3 precursor
703173 PDGFB; platelet-derived growth factor subunit B
613031 TGFA; protransforming growth factor alpha isoform X2
708316 HGF; hepatocyte growth factor isoform X3
704562 MET; hepatocyte growth factor receptor precursor
700367 GAB1; GRB2-associated-binding protein 1
716098 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
709959 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
710552 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
707310 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
719367 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
698996 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
714717 AKT3; RAC-gamma serine/threonine-protein kinase
697747 AKT1; RAC-alpha serine/threonine-protein kinase
700591 AKT2; RAC-beta serine/threonine-protein kinase
717740 BAD; bcl2-associated agonist of cell death
696584 CRKL; crk-like protein
701185 CRK; adapter molecule crk isoform X1
715272 RAPGEF1; rap guanine nucleotide exchange factor 1 isoform X1
704404 RAP1A; ras-related protein Rap-1A
718171 RAP1B; ras-related protein Rap-1b
693750 LOW QUALITY PROTEIN: ras-related protein Rap-1b
712044 PTPN11; tyrosine-protein phosphatase non-receptor type 11
702041 GRB2; growth factor receptor-bound protein 2
713777 SOS1; son of sevenless homolog 1 isoform X1
705601 SOS2; son of sevenless homolog 2
698830 HRAS; GTPase HRas
707977 KRAS; GTPase KRas
709089 NRAS; GTPase NRas
707169 ARAF; serine/threonine-protein kinase A-Raf
693554 BRAF; serine/threonine-protein kinase B-raf isoform X1
694725 RAF1; RAF proto-oncogene serine/threonine-protein kinase
710415 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
721821 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
708938 MAPK3; mitogen-activated protein kinase 3 isoform X1
698569 MAPK1; mitogen-activated protein kinase 1
714697 ETS1; protein C-ets-1 isoform X1
716452 JUN; transcription factor AP-1
717755 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
707637 CDC42; cell division control protein 42 homolog
698585 PAK1; serine/threonine-protein kinase PAK 1 isoform X5
710314 PAK2; serine/threonine-protein kinase PAK 2
706217 PAK3; serine/threonine-protein kinase PAK 3 isoform X1
696676 PAK4; serine/threonine-protein kinase PAK 4 isoform X1
719458 PAK5; serine/threonine-protein kinase PAK 7
701589 PAK6; serine/threonine-protein kinase PAK 6
718660 PRCC; proline-rich protein PRCC
712161 TFE3; transcription factor E3
719199 CDKN1A; cyclin-dependent kinase inhibitor 1
707542 FH; fumarate hydratase, mitochondrial
698082 FLCN; folliculin
|
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03873 ELOB; elongin-B
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03870 CUL2; cullin 2
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K05448 VEGFA; vascular endothelial growth factor A
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K17386 PDGFB; platelet-derived growth factor subunit B
K08774 TGFA; transforming growth factor, alpha
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K07836 RAP1B; Ras-related protein Rap-1B
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1; C-ets-1
K04448 JUN; transcription factor AP-1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04393 CDC42; cell division control protein 42
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K13105 PRCC; proline-rich protein PRCC
K09105 TFE3; transcription factor E3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K09594 FLCN; folliculin
|
05219 Bladder cancer [PATH:mcc05219]
|
05215 Prostate cancer [PATH:mcc05215]
|
05213 Endometrial cancer [PATH:mcc05213]
|
05224 Breast cancer [PATH:mcc05224]
|
05222 Small cell lung cancer [PATH:mcc05222]
|
05223 Non-small cell lung cancer [PATH:mcc05223]
|
|
|
09172 Infectious disease: viral
|
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|
09171 Infectious disease: bacterial
|
|
|
09174 Infectious disease: parasitic
|
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|
09163 Immune disease
|
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|
09164 Neurodegenerative disease
|
|
|
09165 Substance dependence
|
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|
09166 Cardiovascular disease
|
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|
09167 Endocrine and metabolic disease
|
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09175 Drug resistance: antimicrobial
|
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09176 Drug resistance: antineoplastic
|
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09180 Brite Hierarchies
|
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09190 Not Included in Pathway or Brite
|
KEGG Orthology (KO) - Macaca mulatta (rhesus monkey)