Messenger RNA Biogenesis - Mus musculus (mouse)

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     KO
 Eukaryotic type
   mRNA processing factors
   mRNA surveillance and transport factors
     Transport factors
     Surveillance factors
     Factors involved in mRNA localization
     mRNA cycle factors
       Common to processing body (P body) and stress granule
         24127 Xrn1; 5'-3' exoribonuclease 1
         214150 Ago3; argonaute RISC catalytic subunit 3
         236511 Ago1; argonaute RISC catalytic subunit 1
         76850 Ago4; argonaute RISC catalytic subunit 4
         239528 Ago2; argonaute RISC catalytic subunit 2
         13684 Eif4e; eukaryotic translation initiation factor 4E
         26987 Eif4e2; eukaryotic translation initiation factor 4E member 2
         218268 Eif4e1b; eukaryotic translation initiation factor 4E family member 1B
         19704 Upf1; UPF1 regulator of nonsense transcripts homolog (yeast)
         13205 Ddx3x; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
         110957 D1Pas1; DNA segment, Chr 1, Pasteur Institute 1
         26900 Ddx3y; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
         13209 Ddx6; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
         108797 Mex3b; mex3 RNA binding family member B
         237400 Mex3d; mex3 RNA binding family member D
         240396 Mex3c; mex3 RNA binding family member C
         72640 Mex3a; mex3 RNA binding family member A
         66587 Fastk; Fas-activated serine/threonine kinase
         241846 Lsm14b; LSM family member 14B
         67070 Lsm14a; LSM14A mRNA processing body assembly factor
         23983 Pcbp1; poly(rC) binding protein 1
         18521 Pcbp2; poly(rC) binding protein 2
         22608 Ybx1; Y box protein 1
         16475 Ajuba; ajuba LIM protein
         101543 Wtip; WT1-interacting protein
         29806 Limd1; LIM domains containing 1
         11810 Apobec1; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
         80287 Apobec3; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
         17454 Mov10; Mov10 RISC complex RNA helicase
         52830 Pnrc2; proline-rich nuclear receptor coactivator 2
         238799 Tnpo1; transportin 1
         233789 Smg1; SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
         229512 Smg5; Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
         103677 Smg6; Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)
         226517 Smg7; Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
         22695 Zfp36; zinc finger protein 36
         12192 Zfp36l1; zinc finger protein 36, C3H type-like 1
         12193 Zfp36l2; zinc finger protein 36, C3H type-like 2
         380669 Lin28b; lin-28 homolog B (C. elegans)
         83557 Lin28a; lin-28 homolog A (C. elegans)
         15194 Htt; huntingtin
         320727 Ipo8; importin 8
         83675 Bicc1; BicC family RNA binding protein 1
         15382 Hnrnpa1; heterogeneous nuclear ribonucleoprotein A1
         229279 Hnrnpa3; heterogeneous nuclear ribonucleoprotein A3
         545091 Hnrnpa1l2-ps2; heterogeneous nuclear ribonucleoprotein A1-like 2, pseudogene 2
         18747 Prkaca; protein kinase, cAMP dependent, catalytic, alpha
         18749 Prkacb; protein kinase, cAMP dependent, catalytic, beta
         73158 Larp1; La ribonucleoprotein domain family, member 1
         214048 Larp1b; La ribonucleoprotein domain family, member 1B
         20239 Atxn2; ataxin 2
         233871 Atxn2l; ataxin 2-like
K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
K11593 ELF2C; eukaryotic translation initiation factor 2C 
K11593 ELF2C; eukaryotic translation initiation factor 2C 
K11593 ELF2C; eukaryotic translation initiation factor 2C 
K11593 ELF2C; eukaryotic translation initiation factor 2C 
K03259 EIF4E; translation initiation factor 4E 
K03259 EIF4E; translation initiation factor 4E 
K03259 EIF4E; translation initiation factor 4E 
K14326 UPF1; regulator of nonsense transcripts 1 [EC:3.6.4.-] 
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13] 
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13] 
K17642 DDX3Y; ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13] 
K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13] 
K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8] 
K18749 LSM14; protein LSM14 
K18749 LSM14; protein LSM14 
K12889 PCBP1; poly(rC)-binding protein 1 
K13162 PCBP2; poly(rC)-binding protein 2 
K09276 YBX1; Y-box-binding protein 1 
K16682 AJUBA; LIM domain-containing protein 
K16682 AJUBA; LIM domain-containing protein 
K16682 AJUBA; LIM domain-containing protein 
K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36] 
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-] 
K18422 MOV10; helicase MOV-10 [EC:3.6.4.13] 
K18751 PNRC2; proline-rich nuclear receptor coactivator 2 
K18752 TNPO1; transportin-1 
K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1] 
K11125 SMG5; protein SMG5 
K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
K14409 SMG7; protein SMG7 
K15308 TTP; tristetraprolin 
K18753 ZFP36L; butyrate response factor 
K18753 ZFP36L; butyrate response factor 
K18754 LIN28; protein lin-28 
K18754 LIN28; protein lin-28 
K04533 HD; huntingtin 
K18755 IPO8; importin-8 
K18756 BICC1; protein bicaudal C 
K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K18757 LARP1; la-related protein 1 
K18757 LARP1; la-related protein 1 
K23625 ATXN2_2L; ataxin 2/2L 
K23625 ATXN2_2L; ataxin 2/2L 
       P-body specific factors
       Stress granule specific factors
   mRNA degradation factors
 
 Prokaryotic type

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Last updated: August 8, 2019