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KO |
Eukaryotic type
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Sister chromatid cohesion proteins
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Meiosis-specific proteins
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Nucleosome assembly factors
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Histone modification proteins
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HATs (histone acetyltransferases)
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HAT complexes
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HDACs (histone deacetylases)
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HDAC complexes
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HMTs (histone methyltransferases)
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HKMTs (histone lysine methyltransferases)
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192195 Ash1l; ASH1 like histone lysine methyltransferase
208266 Dot1l; DOT1 like histone lysine methyltransferase
110147 Ehmt2; euchromatic histone lysine N-methyltransferase 2
77683 Ehmt1; euchromatic histone methyltransferase 1
14055 Ezh1; enhancer of zeste 1 polycomb repressive complex 2 subunit
14056 Ezh2; enhancer of zeste 2 polycomb repressive complex 2 subunit
214162 Kmt2a; lysine (K)-specific methyltransferase 2A
381022 Kmt2d; lysine (K)-specific methyltransferase 2D
231051 Kmt2c; lysine (K)-specific methyltransferase 2C
75410 Kmt2b; lysine (K)-specific methyltransferase 2B
69188 Kmt2e; lysine (K)-specific methyltransferase 2E
18193 Nsd1; nuclear receptor-binding SET-domain protein 1
107823 Nsd2; nuclear receptor binding SET domain protein 2
234135 Nsd3; nuclear receptor binding SET domain protein 3
110593 Prdm2; PR domain containing 2, with ZNF domain
14013 Mecom; MDS1 and EVI1 complex locus
225518 Prdm6; PR domain containing 6
213389 Prdm9; PR domain containing 9
77630 Prdm8; PR domain containing 8
381359 Prdm12; PR domain containing 12
70673 Prdm16; PR domain containing 16
233904 Setd1a; SET domain containing 1A
208043 Setd1b; SET domain containing 1B
235626 Setd2; SET domain containing 2
224440 Setd4; SET domain containing 4
66083 Setd6; SET domain containing 6
73251 Setd7; SET domain containing (lysine methyltransferase) 7
67956 Kmt5a; lysine methyltransferase 5A
84505 Setdb1; SET domain, bifurcated 1
239122 Setdb2; SET domain, bifurcated 2
107303348 Gm45935; predicted gene, 45935
74729 Setmar; SET domain without mariner transposase fusion
226830 Smyd2; SET and MYND domain containing 2
69726 Smyd3; SET and MYND domain containing 3
12180 Smyd1; SET and MYND domain containing 1
20937 Suv39h1; suppressor of variegation 3-9 1
64707 Suv39h2; suppressor of variegation 3-9 2
232811 Kmt5c; lysine methyltransferase 5C
225888 Kmt5b; lysine methyltransferase 5B
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K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
K09187 MLL2; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354]
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
K11424 WHSC1; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357]
K11425 WHSC1L1; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371]
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361]
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-]
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359]
K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364]
K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355]
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355]
K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
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PRMTs (protein arginine metyltransferases)
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HMT complexes
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COMPASS/SET1 complex
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233904 Setd1a; SET domain containing 1A
208043 Setd1b; SET domain containing 1B
74322 Cxxc1; CXXC finger protein 1
213464 Rbbp5; retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit
77305 Wdr82; WD repeat domain containing 82
69544 Wdr5b; WD repeat domain 5B
140858 Wdr5; WD repeat domain 5
23808 Ash2l; ASH2 like histone lysine methyltransferase complex subunit
66310 Dpy30; dpy-30, histone methyltransferase complex regulatory subunit
15161 Hcfc1; host cell factor C1
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K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K14960 CXXC1; COMPASS component SPP1
K14961 RBBP5; COMPASS component SWD1
K14962 WDR82; COMPASS component SWD2
K14963 WDR5; COMPASS component SWD3
K14963 WDR5; COMPASS component SWD3
K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
K14965 DPY30; protein dpy-30
K14966 HCFC1; host cell factor 1
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COMPASS/SET1 complex (yeast)
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233904 Setd1a; SET domain containing 1A
208043 Setd1b; SET domain containing 1B
74322 Cxxc1; CXXC finger protein 1
213464 Rbbp5; retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit
77305 Wdr82; WD repeat domain containing 82
69544 Wdr5b; WD repeat domain 5B
140858 Wdr5; WD repeat domain 5
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K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K14960 CXXC1; COMPASS component SPP1
K14961 RBBP5; COMPASS component SWD1
K14962 WDR82; COMPASS component SWD2
K14963 WDR5; COMPASS component SWD3
K14963 WDR5; COMPASS component SWD3
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MLL-HCF complex
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MLL3/MLL4 complex
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Dot1-containing complex
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Histone demethylases
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Polycomb repressive complex (PRC) and associated proteins
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Sir proteins
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Other histone modification proteins
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Chromosome condensation proteins
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Centromeric chromatin formation proteins
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Heterochromatin formation proteins
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Gene silencing
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Centrosome formation proteins
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Sister chromatid separation proteins
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Chromatin remodeling factors
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Prokaryotic type
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