Chromosome and Associated Proteins - Mus musculus (house mouse)

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     KO
 Eukaryotic type
   Sister chromatid cohesion proteins
   Meiosis-specific proteins
   Nucleosome assembly factors
   Histone modification proteins
     HATs (histone acetyltransferases)
     HAT complexes
     HDACs (histone deacetylases)
     HDAC complexes
     HMTs (histone methyltransferases)
       HKMTs (histone lysine methyltransferases)
         192195 Ash1l; ASH1 like histone lysine methyltransferase
         208266 Dot1l; DOT1 like histone lysine methyltransferase
         110147 Ehmt2; euchromatic histone lysine N-methyltransferase 2
         77683 Ehmt1; euchromatic histone methyltransferase 1
         14055 Ezh1; enhancer of zeste 1 polycomb repressive complex 2 subunit
         14056 Ezh2; enhancer of zeste 2 polycomb repressive complex 2 subunit
         214162 Kmt2a; lysine (K)-specific methyltransferase 2A
         381022 Kmt2d; lysine (K)-specific methyltransferase 2D
         231051 Kmt2c; lysine (K)-specific methyltransferase 2C
         75410 Kmt2b; lysine (K)-specific methyltransferase 2B
         69188 Kmt2e; lysine (K)-specific methyltransferase 2E
         18193 Nsd1; nuclear receptor-binding SET-domain protein 1
         107823 Nsd2; nuclear receptor binding SET domain protein 2
         234135 Nsd3; nuclear receptor binding SET domain protein 3
         110593 Prdm2; PR domain containing 2, with ZNF domain
         14013 Mecom; MDS1 and EVI1 complex locus
         225518 Prdm6; PR domain containing 6
         213389 Prdm9; PR domain containing 9
         77630 Prdm8; PR domain containing 8
         381359 Prdm12; PR domain containing 12
         70673 Prdm16; PR domain containing 16
         233904 Setd1a; SET domain containing 1A
         208043 Setd1b; SET domain containing 1B
         235626 Setd2; SET domain containing 2
         224440 Setd4; SET domain containing 4
         66083 Setd6; SET domain containing 6
         73251 Setd7; SET domain containing (lysine methyltransferase) 7
         67956 Kmt5a; lysine methyltransferase 5A
         84505 Setdb1; SET domain, bifurcated 1
         239122 Setdb2; SET domain, bifurcated 2
         107303348 Gm45935; predicted gene, 45935
         74729 Setmar; SET domain without mariner transposase fusion
         226830 Smyd2; SET and MYND domain containing 2
         69726 Smyd3; SET and MYND domain containing 3
         12180 Smyd1; SET and MYND domain containing 1
         20937 Suv39h1; suppressor of variegation 3-9 1
         64707 Suv39h2; suppressor of variegation 3-9 2
         232811 Kmt5c; lysine methyltransferase 5C
         225888 Kmt5b; lysine methyltransferase 5B
K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354] 
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360] 
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355] 
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355] 
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356] 
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356] 
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354] 
K09187 MLL2; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354] 
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354] 
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354] 
K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354] 
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357] 
K11424 WHSC1; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357] 
K11425 WHSC1L1; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371] 
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355] 
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367] 
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361] 
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354] 
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-] 
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-] 
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367] 
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354] 
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354] 
K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359] 
K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364] 
K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-] 
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364] 
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361] 
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366] 
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355] 
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355] 
K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355] 
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355] 
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362] 
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362] 
       PRMTs (protein arginine metyltransferases)
     HMT complexes
       COMPASS/SET1 complex
         233904 Setd1a; SET domain containing 1A
         208043 Setd1b; SET domain containing 1B
         74322 Cxxc1; CXXC finger protein 1
         213464 Rbbp5; retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit
         77305 Wdr82; WD repeat domain containing 82
         69544 Wdr5b; WD repeat domain 5B
         140858 Wdr5; WD repeat domain 5
         23808 Ash2l; ASH2 like histone lysine methyltransferase complex subunit
         66310 Dpy30; dpy-30, histone methyltransferase complex regulatory subunit
         15161 Hcfc1; host cell factor C1
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354] 
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354] 
K14960 CXXC1; COMPASS component SPP1 
K14961 RBBP5; COMPASS component SWD1 
K14962 WDR82; COMPASS component SWD2 
K14963 WDR5; COMPASS component SWD3 
K14963 WDR5; COMPASS component SWD3 
K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2 
K14965 DPY30; protein dpy-30 
K14966 HCFC1; host cell factor 1 
       COMPASS/SET1 complex (yeast)
         233904 Setd1a; SET domain containing 1A
         208043 Setd1b; SET domain containing 1B
         74322 Cxxc1; CXXC finger protein 1
         213464 Rbbp5; retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit
         77305 Wdr82; WD repeat domain containing 82
         69544 Wdr5b; WD repeat domain 5B
         140858 Wdr5; WD repeat domain 5
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354] 
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354] 
K14960 CXXC1; COMPASS component SPP1 
K14961 RBBP5; COMPASS component SWD1 
K14962 WDR82; COMPASS component SWD2 
K14963 WDR5; COMPASS component SWD3 
K14963 WDR5; COMPASS component SWD3 
       MLL-HCF complex
       MLL3/MLL4 complex
       Dot1-containing complex
     Histone demethylases
     Polycomb repressive complex (PRC) and associated proteins
     Sir proteins
     Other histone modification proteins
   Chromosome condensation proteins
   Centromeric chromatin formation proteins
   Heterochromatin formation proteins
   Gene silencing
   Centrosome formation proteins
   Sister chromatid separation proteins
   Chromatin remodeling factors
 
 Prokaryotic type

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Last updated: April 10, 2024