KEGG Orthology (KO) - Mycobacterium tuberculosis HKBS1

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 09100 Metabolism

 





   09101 Carbohydrate metabolism





     00010 Glycolysis / Gluconeogenesis [PATH:mtq00010]





     00020 Citrate cycle (TCA cycle) [PATH:mtq00020]





       HKBS1_1200 gltA1; citrate synthase
       HKBS1_0935 citA; citrate synthase II
       HKBS1_0942 gltA2; citrate synthase I
       HKBS1_1576 acn; aconitate hydratase
       HKBS1_3534 icd1; isocitrate dehydrogenase
       HKBS1_0073 icd2; isocitrate dehydrogenase
       HKBS1_1330 kgd; alpha-ketoglutarate decarboxylase
       HKBS1_0480 lpd; dihydrolipoamide dehydrogenase
       HKBS1_2600 ferredoxin oxidoreductase subunit alpha
       HKBS1_2599 2-oxoglutarate ferredoxin oxidoreductase subunit beta
       HKBS1_1002 sucD; succinyl-CoA synthetase subunit alpha
       HKBS1_1001 sucC; succinyl-CoA synthetase subunit beta
       HKBS1_3508 sdhA; succinate dehydrogenase flavoprotein subunit
       HKBS1_0265 succinate dehydrogenase iron-sulfur subunit
       HKBS1_3509 sdhB; succinate dehydrogenase iron-sulfur subunit
       HKBS1_0264 succinate dehydrogenase iron-sulfur subunit
       HKBS1_3506 sdhC; succinate dehydrogenase cytochrome B-556 subunit SdhC
       HKBS1_3507 sdhD; succinate dehydrogenase hydrophobic membrane anchor subunit SdhD
       HKBS1_1659 frdA; fumarate reductase flavoprotein subunit
       HKBS1_1660 frdB; fumarate reductase iron-sulfur subunit FrdB
       HKBS1_1661 frdC; fumarate reductase subunit C
       HKBS1_1662 frdD; fumarate reductase subunit D
       HKBS1_1165 fumC; fumarate hydratase
       HKBS1_1322 mdh; malate dehydrogenase
       HKBS1_3002 mqo; malate:quinone oxidoreductase
       HKBS1_3123 pca; pyruvate carboxylase
       HKBS1_0227 pckA; iron-regulated phosphoenolpyruvate carboxykinase
       HKBS1_2370 aceE; pyruvate dehydrogenase subunit E1
       HKBS1_2341 dlaT; dihydrolipoamide acetyltransferase



K01647 CS; citrate synthase [EC:2.3.3.1]
K01647 CS; citrate synthase [EC:2.3.3.1]
K01647 CS; citrate synthase [EC:2.3.3.1]
K01681 ACO; aconitate hydratase [EC:4.2.1.3]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K01616 kgd; multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00241 sdhC; succinate dehydrogenase cytochrome b subunit
K00242 sdhD; succinate dehydrogenase membrane anchor subunit
K00244 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00245 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00246 frdC; succinate dehydrogenase subunit C
K00247 frdD; succinate dehydrogenase subunit D
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
K00116 mqo; malate dehydrogenase (quinone) [EC:1.1.5.4]
K01958 PC; pyruvate carboxylase [EC:6.4.1.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]





     00030 Pentose phosphate pathway [PATH:mtq00030]





     00040 Pentose and glucuronate interconversions [PATH:mtq00040]





     00051 Fructose and mannose metabolism [PATH:mtq00051]





     00052 Galactose metabolism [PATH:mtq00052]





     00053 Ascorbate and aldarate metabolism [PATH:mtq00053]





     00500 Starch and sucrose metabolism [PATH:mtq00500]





     00520 Amino sugar and nucleotide sugar metabolism [PATH:mtq00520]





     00620 Pyruvate metabolism [PATH:mtq00620]





     00630 Glyoxylate and dicarboxylate metabolism [PATH:mtq00630]





     00640 Propanoate metabolism [PATH:mtq00640]





     00650 Butanoate metabolism [PATH:mtq00650]





       HKBS1_0902 fadA; acyl-CoA thiolase FadA
       HKBS1_3759 fadA5; acetyl-CoA acetyltransferase
       HKBS1_3769 fadA6; acetyl-CoA acetyltransferase
       HKBS1_0962 lipid carrier protein or keto acyl-CoA thiolase
       HKBS1_1960 acetyl-CoA acetyltransferase
       HKBS1_3736 ltp3; acetyl-CoA acetyltransferase
       HKBS1_0260 fadA2; acetyl-CoA acyltransferase FadA2
       HKBS1_1137 fadA3; acetyl-CoA acetyltransferase
       HKBS1_1411 fadA4; acetyl-CoA acetyltransferase
       HKBS1_1811 fadB3; 3-hydroxybutyryl-CoA dehydrogenase FadB3
       HKBS1_0486 3-hydroxybutyryl-CoA dehydrogenase
       HKBS1_0903 fadB; fatty-acid oxidation protein FadB
       HKBS1_1133 echA8; enoyl-CoA hydratase
       HKBS1_2631 echA14; enoyl-CoA hydratase
       HKBS1_1572 echA12; enoyl-CoA hydratase
       HKBS1_3205 echA17; enoyl-CoA hydratase
       HKBS1_3748 acetaldehyde dehydrogenase
       HKBS1_3508 sdhA; succinate dehydrogenase flavoprotein subunit
       HKBS1_0265 succinate dehydrogenase iron-sulfur subunit
       HKBS1_3509 sdhB; succinate dehydrogenase iron-sulfur subunit
       HKBS1_0264 succinate dehydrogenase iron-sulfur subunit
       HKBS1_3506 sdhC; succinate dehydrogenase cytochrome B-556 subunit SdhC
       HKBS1_3507 sdhD; succinate dehydrogenase hydrophobic membrane anchor subunit SdhD
       HKBS1_1659 frdA; fumarate reductase flavoprotein subunit
       HKBS1_1660 frdB; fumarate reductase iron-sulfur subunit FrdB
       HKBS1_1661 frdC; fumarate reductase subunit C
       HKBS1_1662 frdD; fumarate reductase subunit D
       HKBS1_3646 gadB; glutamate decarboxylase
       HKBS1_2738 gabT; 4-aminobutyrate aminotransferase
       HKBS1_0250 gabD1; succinate-semialdehyde dehydrogenase [NADP+] dependent
       HKBS1_1829 gabD2; succinate-semialdehyde dehydrogenase [NADP+]-dependent
       HKBS1_2600 ferredoxin oxidoreductase subunit alpha
       HKBS1_2599 2-oxoglutarate ferredoxin oxidoreductase subunit beta
       HKBS1_2651 scoA; succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A
       HKBS1_2650 scoB; succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B
       HKBS1_3684 ilvB2; putative acetolactate synthase large subunit
       HKBS1_3162 ilvB1; acetolactate synthase large subunit
       HKBS1_3722 ilvX; acetohydroxyacid synthase
       HKBS1_3161 ilvN; acetolactate synthase small subunit



K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
K04073 mhpF; acetaldehyde dehydrogenase [EC:1.2.1.10]
K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00241 sdhC; succinate dehydrogenase cytochrome b subunit
K00242 sdhD; succinate dehydrogenase membrane anchor subunit
K00244 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00245 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00246 frdC; succinate dehydrogenase subunit C
K00247 frdD; succinate dehydrogenase subunit D
K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
K01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]
K01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]
K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]





     00660 C5-Branched dibasic acid metabolism [PATH:mtq00660]





     00562 Inositol phosphate metabolism [PATH:mtq00562]





 







   09102 Energy metabolism





     00190 Oxidative phosphorylation [PATH:mtq00190]





       HKBS1_3320 nuoA; NADH dehydrogenase subunit A
       HKBS1_3321 nuoB; NADH dehydrogenase subunit B
       HKBS1_3322 nuoC; NADH dehydrogenase subunit C
       HKBS1_3323 nuoD; NADH dehydrogenase subunit D
       HKBS1_3324 nuoE; NADH dehydrogenase subunit E
       HKBS1_3325 nuoF; NADH dehydrogenase subunit F
       HKBS1_3326 nuoG; NADH dehydrogenase subunit G
       HKBS1_3327 nuoH; NADH dehydrogenase subunit H
       HKBS1_3328 nuoI; NADH dehydrogenase subunit I
       HKBS1_3329 nuoJ; NADH dehydrogenase subunit J
       HKBS1_3330 nuoK; NADH dehydrogenase subunit K
       HKBS1_3331 nuoL; NADH dehydrogenase subunit L
       HKBS1_3332 nuoM; NADH dehydrogenase subunit M
       HKBS1_3333 nuoN; NADH dehydrogenase subunit N
       HKBS1_0407 ndhA; membrane NADH dehydrogenase
       HKBS1_1905 putative dehydrogenase
       HKBS1_1947 ndh; NADH dehydrogenase Ndh
       HKBS1_3508 sdhA; succinate dehydrogenase flavoprotein subunit
       HKBS1_0265 succinate dehydrogenase iron-sulfur subunit
       HKBS1_3509 sdhB; succinate dehydrogenase iron-sulfur subunit
       HKBS1_0264 succinate dehydrogenase iron-sulfur subunit
       HKBS1_3506 sdhC; succinate dehydrogenase cytochrome B-556 subunit SdhC
       HKBS1_3507 sdhD; succinate dehydrogenase hydrophobic membrane anchor subunit SdhD
       HKBS1_1659 frdA; fumarate reductase flavoprotein subunit
       HKBS1_1660 frdB; fumarate reductase iron-sulfur subunit FrdB
       HKBS1_1661 frdC; fumarate reductase subunit C
       HKBS1_1662 frdD; fumarate reductase subunit D
       HKBS1_2321 qcrA; putative iron-sulfur protein
       HKBS1_2322 qcrB; ubiquinol-cytochrome C reductase QcrB
       HKBS1_2320 qcrC; cytochrome c family protein
       HKBS1_1549 ctaB; protoheme IX farnesyltransferase
       HKBS1_2325 putative integral membrane protein
       HKBS1_2319 ctaE; cytochrome c oxidase subunit III
       HKBS1_3209 ctaD; cytochrome c oxidase subunit I
       HKBS1_2326 ctaC; cytochrome c oxidase subunit II
       HKBS1_1554 antibiotic ABC transporter permease
       HKBS1_1716 cydA; cytochrome d ubiquinol oxidase subunit I
       HKBS1_1715 cydB; cytochrome d ubiquinol oxidase subunit II
       HKBS1_1393 atpA; F0F1 ATP synthase subunit alpha
       HKBS1_1395 atpD; F0F1 ATP synthase subunit beta
       HKBS1_1394 atpG; F0F1 ATP synthase subunit gamma
       HKBS1_1392 atpH; F0F1 ATP synthase subunit delta
       HKBS1_1396 atpC; F0F1 ATP synthase subunit epsilon
       HKBS1_1389 atpB; F0F1 ATP synthase subunit A
       HKBS1_1391 atpF; F0F1 ATP synthase subunit B
       HKBS1_1390 atpE; F0F1 ATP synthase subunit C
       HKBS1_3841 ppa; inorganic pyrophosphatase
       HKBS1_3141 ppk; polyphosphate kinase
       HKBS1_3419 pvdS; putative RNA polymerase sigma factor



K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]
K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00241 sdhC; succinate dehydrogenase cytochrome b subunit
K00242 sdhD; succinate dehydrogenase membrane anchor subunit
K00244 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00245 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00246 frdC; succinate dehydrogenase subunit C
K00247 frdD; succinate dehydrogenase subunit D
K03890 qcrA; quinol---cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K03891 qcrB; quinol---cytochrome-c reductase cytochrome b subunit [EC:7.1.1.8]
K03889 qcrC; quinol---cytochrome-c reductase cytochrome c subunit [EC:7.1.1.8]
K02257 COX10; heme o synthase [EC:2.5.1.141]
K27109 ctaF; cytochrome c oxidase subunit IV [EC:7.1.1.9]
K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]
K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
K02259 COX15; heme a synthase [EC:1.17.99.9]
K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
K02109 ATPF0B; F-type H+-transporting ATPase subunit b
K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
K02108 ATPF0A; F-type H+-transporting ATPase subunit a
K02109 ATPF0B; F-type H+-transporting ATPase subunit b
K02110 ATPF0C; F-type H+-transporting ATPase subunit c
K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
K22468 ppk2; polyphosphate kinase [EC:2.7.4.34]





     00195 Photosynthesis





     00196 Photosynthesis - antenna proteins





     00710 Carbon fixation in photosynthetic organisms





     00720 Carbon fixation pathways in prokaryotes





     00680 Methane metabolism [PATH:mtq00680]





     00910 Nitrogen metabolism [PATH:mtq00910]





     00920 Sulfur metabolism [PATH:mtq00920]





 







   09103 Lipid metabolism





 







   09104 Nucleotide metabolism





 







   09105 Amino acid metabolism





 







   09106 Metabolism of other amino acids





 







   09107 Glycan biosynthesis and metabolism





 







   09108 Metabolism of cofactors and vitamins





 







   09109 Metabolism of terpenoids and polyketides





 







   09110 Biosynthesis of other secondary metabolites





 







   09111 Xenobiotics biodegradation and metabolism





 







   09112 Not included in regular maps





 







 09120 Genetic Information Processing





 







 09130 Environmental Information Processing





 







 09140 Cellular Processes





 







 09150 Organismal Systems





 







 09160 Human Diseases





 







 09180 Brite Hierarchies





 







 09190 Not Included in Pathway or Brite













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Last updated: April 23, 2024