KEGG Orthology (KO) - Oryctolagus cuniculus (rabbit)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
   09121 Transcription
 
   09122 Translation
 
   09123 Folding, sorting and degradation
 
   09124 Replication and repair
     03030 DNA replication [PATH:ocu03030]
     03410 Base excision repair [PATH:ocu03410]
     03420 Nucleotide excision repair [PATH:ocu03420]
       103352470 RBX1; ring-box 1
       100354247 CUL4A; cullin 4A
       100351102 CUL4B; cullin 4B
       100354475 DDB1; damage specific DNA binding protein 1
       100352386 DDB2; damage specific DNA binding protein 2
       100346279 XPC; XPC complex subunit, DNA damage recognition and repair factor
       100353489 RAD23B; RAD23 homolog B, nucleotide excision repair protein
       108178685 UV excision repair protein RAD23 homolog B-like
       100350600 CETN2; centrin 2
       100352258 ERCC8; ERCC excision repair 8, CSA ubiquitin ligase complex subunit
       100345784 ERCC6; ERCC excision repair 6, chromatin remodeling factor
       100358882 CDK7; cyclin dependent kinase 7
       100349698 MNAT1; MNAT1, CDK activating kinase assembly factor
       100358948 CCNH; cyclin H
       100348395 ERCC3; ERCC excision repair 3, TFIIH core complex helicase subunit
       100347957 ERCC2; ERCC excision repair 2, TFIIH core complex helicase subunit
       103349943 GTF2H5; general transcription factor IIH subunit 5
       100342919 GTF2H1; general transcription factor IIH subunit 1
       100338745 general transcription factor IIH subunit 2
       100347110 GTF2H3; general transcription factor IIH subunit 3
       108175387 ERCC5; ERCC excision repair 5, endonuclease
       108178030 XPA; XPA, DNA damage recognition and repair factor
       100341460 RPA1; replication protein A1
       100347550 RPA2; replication protein A2
       100358262 RPA3; replication protein A3
       103351965 RPA4; replication protein A4
       100350642 ERCC4; ERCC excision repair 4, endonuclease catalytic subunit
       100348713 ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit
       100358263 POLD2; DNA polymerase delta 2, accessory subunit
       100357626 POLD3; DNA polymerase delta 3, accessory subunit
       100356010 POLD4; DNA polymerase delta 4, accessory subunit
       100338950 POLE; DNA polymerase epsilon, catalytic subunit
       100345613 POLE2; DNA polymerase epsilon 2, accessory subunit
       100355895 POLE3; DNA polymerase epsilon 3, accessory subunit
       100358589 POLE4; DNA polymerase epsilon 4, accessory subunit
       100339381 PCNA; proliferating cell nuclear antigen
       100352565 RFC1; replication factor C subunit 1
       100343517 RFC2; replication factor C subunit 2
       100342140 RFC4; replication factor C subunit 4
       100339186 RFC3; replication factor C subunit 3
       100345366 RFC5; replication factor C subunit 5
       100340979 LIG1; DNA ligase 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K10609 CUL4; cullin 4
K10609 CUL4; cullin 4
K10610 DDB1; DNA damage-binding protein 1
K10140 DDB2; DNA damage-binding protein 2
K10838 XPC; xeroderma pigmentosum group C-complementing protein
K10839 RAD23; UV excision repair protein RAD23
K10839 RAD23; UV excision repair protein RAD23
K10840 CETN2; centrin-2
K10570 ERCC8; DNA excision repair protein ERCC-8
K10841 ERCC6; DNA excision repair protein ERCC-6
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K10842 MNAT1; CDK-activating kinase assembly factor MAT1
K06634 CCNH; cyclin H
K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:3.6.4.12]
K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:3.6.4.12]
K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
K10846 ERCC5; DNA excision repair protein ERCC-5
K10847 XPA; DNA-repair protein complementing XP-A cells
K07466 RFA1; replication factor A1
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K10741 RPA4; replication factor A4
K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K10849 ERCC1; DNA excision repair protein ERCC-1
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K04802 PCNA; proliferating cell nuclear antigen
K10754 RFC1; replication factor C subunit 1
K10755 RFC2_4; replication factor C subunit 2/4
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K10756 RFC3_5; replication factor C subunit 3/5
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
     03430 Mismatch repair [PATH:ocu03430]
     03440 Homologous recombination [PATH:ocu03440]
     03450 Non-homologous end-joining [PATH:ocu03450]
     03460 Fanconi anemia pathway [PATH:ocu03460]
       100355293 ATRIP; ATR interacting protein
       100359062 ATR; ATR serine/threonine kinase
       100354209 FANCM; Fanconi anemia complementation group M
       100357310 FAAP24; Fanconi anemia core complex associated protein 24
       100534620 CENPS; centromere protein S
       100354742 CENPX; centromere protein X
       100356602 TELO2; telomere maintenance 2
       100358704 HES1; hes family bHLH transcription factor 1
       108176186 Fanconi anemia core complex-associated protein 100-like
       100340806 FANCA; Fanconi anemia complementation group A
       100355151 FANCB; Fanconi anemia complementation group B
       100344788 FANCC; Fanconi anemia complementation group C
       100359053 FANCE; Fanconi anemia complementation group E
       100340638 FANCF; Fanconi anemia complementation group F
       100346331 FANCG; Fanconi anemia complementation group G
       100344973 FANCL; Fanconi anemia complementation group L
       100354945 WDR48; WD repeat domain 48
       100358366 USP1; ubiquitin specific peptidase 1
       100357338 UBE2T; ubiquitin conjugating enzyme E2 T
       100347941 FANCI; Fanconi anemia complementation group I
       100346581 FANCD2; Fanconi anemia complementation group D2
       100355331 BRCA2; BRCA2, DNA repair associated
       100356031 PALB2; partner and localizer of BRCA2
       100339674 RAD51C; RAD51 paralog C
       100008661 RAD51; RAD51 recombinase
       100347269 BRCA1; BRCA1, DNA repair associated
       100359326 BRIP1; BRCA1 interacting protein C-terminal helicase 1
       100345357 FAN1; FANCD2 and FANCI associated nuclease 1
       100337912 MLH1; mutL homolog 1
       100355997 PMS2; PMS1 homolog 2, mismatch repair system component
       100345920 REV1; REV1, DNA directed polymerase
       100359215 REV3L; REV3 like, DNA directed polymerase zeta catalytic subunit
       100357494 POLH; DNA polymerase eta
       100342545 POLI; DNA polymerase iota
       100352218 POLK; DNA polymerase kappa
       100349293 POLN; DNA polymerase nu
       100352297 RMI1; RecQ mediated genome instability 1
       100348643 RMI2; RecQ mediated genome instability 2
       100338026 TOP3A; topoisomerase (DNA) III alpha
       100345272 TOP3B; topoisomerase (DNA) III beta
       100345123 BLM; Bloom syndrome RecQ like helicase
       100341460 RPA1; replication protein A1
       100347550 RPA2; replication protein A2
       100358262 RPA3; replication protein A3
       103351965 RPA4; replication protein A4
       100341582 MUS81; MUS81 structure-specific endonuclease subunit
       100341377 EME1; essential meiotic structure-specific endonuclease 1
       100350642 ERCC4; ERCC excision repair 4, endonuclease catalytic subunit
       100348713 ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit
       103348603 SLX1A; SLX1 homolog A, structure-specific endonuclease subunit
       100347540 SLX4; SLX4 structure-specific endonuclease subunit
K10905 ATRIP; ATR interacting protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K10896 FANCM; fanconi anemia group M protein
K10898 FAAP24; fanconi anemia-associated protein
K11511 APITD1; centromere protein S
K15360 STRA13; centromere protein X
K11137 TELO2; telomere length regulation protein
K06054 HES1; hairy and enhancer of split 1
K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
K10888 FANCA; fanconi anemia group A protein
K10889 FANCB; fanconi anemia group B protein
K10890 FANCC; fanconi anemia group C protein
K10892 FANCE; fanconi anemia group E protein
K10893 FANCF; fanconi anemia group F protein
K10894 FANCG; fanconi anemia group G protein
K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
K15361 WDR48; WD repeat-containing protein 48
K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
K10895 FANCI; fanconi anemia group I protein
K10891 FANCD2; fanconi anemia group D2 protein
K08775 BRCA2; breast cancer 2 susceptibility protein
K10897 PALB2; partner and localizer of BRCA2
K10870 RAD51L2; RAD51-like protein 2
K04482 RAD51; DNA repair protein RAD51
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K15362 BRIP1; fanconi anemia group J protein [EC:3.6.4.12]
K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
K08734 MLH1; DNA mismatch repair protein MLH1
K10858 PMS2; DNA mismatch repair protein PMS2
K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
K10990 RMI1; RecQ-mediated genome instability protein 1
K15365 RMI2; RecQ-mediated genome instability protein 2
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K10901 BLM; bloom syndrome protein [EC:3.6.4.12]
K07466 RFA1; replication factor A1
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K10741 RPA4; replication factor A4
K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K10849 ERCC1; DNA excision repair protein ERCC-1
K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
     01521 EGFR tyrosine kinase inhibitor resistance [PATH:ocu01521]
     01524 Platinum drug resistance [PATH:ocu01524]
       100349206 SLC31A1; solute carrier family 31 member 1
       100344865 ATP7B; ATPase copper transporting beta
       100343248 ATP7A; ATPase copper transporting alpha
       100353174 glutathione S-transferase 3
       100353681 glutathione S-transferase alpha I
       100353428 glutathione S-transferase Yc
       100341104 glutathione S-transferase Yc
       100353927 glutathione S-transferase alpha I
       100354186 glutathione S-transferase Yc
       100354436 glutathione S-transferase A4
       100341622 GSTA4; glutathione S-transferase A4
       100340711 glutathione S-transferase theta-1-like
       100338449 glutathione S-transferase theta-2B
       100338194 glutathione S-transferase theta-1
       100009073 GSTM2; glutathione S-transferase mu 2 (muscle)
       100340829 MGST1; microsomal glutathione S-transferase 1
       100356052 GSTM3; glutathione S-transferase mu 3
       100356307 glutathione S-transferase Mu 1
       100357148 glutathione S-transferase Yb-3
       100328911 glutathione S-transferase Yc
       100008879 MGST3; microsomal glutathione S-transferase 3
       103350707 MGST2; microsomal glutathione S-transferase 2
       100328910 glutathione S-transferase alpha I
       100339996 glutathione S-transferase Mu 1-like
       100357403 glutathione S-transferase Yb-3-like
       100357917 glutathione S-transferase Mu 1
       100358177 GSTM4; glutathione S-transferase Mu 1
       100349021 GSTO1; glutathione S-transferase omega 1
       100339842 GSTO2; glutathione S-transferase omega-2
       100340967 glutathione S-transferase theta-4
       100342268 GSTP1; glutathione S-transferase pi 1
       100343242 ABCC2; ATP binding cassette subfamily C member 2
       100357494 POLH; DNA polymerase eta
       100359215 REV3L; REV3 like, DNA directed polymerase zeta catalytic subunit
       103347805 MSH2; mutS homolog 2
       100337807 MSH3; mutS homolog 3
       100351645 MSH6; mutS homolog 6
       100337912 MLH1; mutL homolog 1
       108178030 XPA; XPA, DNA damage recognition and repair factor
       100348713 ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit
       100351427 TOP2B; topoisomerase (DNA) II beta
       100357676 TOP2A; topoisomerase (DNA) II alpha
       100347269 BRCA1; BRCA1, DNA repair associated
       100349299 ATM; ATM serine/threonine kinase
       100009292 TP53; tumor protein p53
       100340625 CDKN2A; cyclin-dependent kinase inhibitor 2A
       100340389 MDM2; MDM2 proto-oncogene
       100008609 FAS; Fas cell surface death receptor
       100355675 BAX; BCL2 associated X, apoptosis regulator
       100342046 BAK1; BCL2 antagonist/killer 1
       103349392 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       100357703 BBC3; BCL2 binding component 3
       100344073 FASLG; Fas ligand
       103346753 FADD; Fas associated via death domain
       100348477 CASP8; caspase 8
       100008840 CASP3; caspase 3
       100355991 BID; BH3 interacting domain death agonist
       100340120 BIRC3; baculoviral IAP repeat containing 3
       100338118 BIRC2; baculoviral IAP repeat containing 2
       100328700 XIAP; X-linked inhibitor of apoptosis
       103346801 BIRC5; baculoviral IAP repeat containing 5
       100009554 ERBB2; erb-b2 receptor tyrosine kinase 2
       100348663 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       100345181 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       100337822 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       100357841 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       100345250 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       100347954 PDPK1; 3-phosphoinositide dependent protein kinase 1
       100342852 AKT2; AKT serine/threonine kinase 2
       100353706 AKT3; AKT serine/threonine kinase 3
       100348489 CDKN1A; cyclin dependent kinase inhibitor 1A
       100340498 MAP3K5; mitogen-activated protein kinase kinase kinase 5
       100347345 MAPK1; mitogen-activated protein kinase 1
       100348561 MAPK3; mitogen-activated protein kinase 3
       100358587 BAD; BCL2 associated agonist of cell death
       100008875 BCL2L1; BCL2 like 1
       103349397 BCL2; BCL2, apoptosis regulator
       100357840 cytochrome c-like
       100355084 cytochrome c
       100341050 cytochrome c-like
       100354468 cytochrome c-like
       100357329 cytochrome c
       100341515 cytochrome c-like
       100353673 cytochrome c
       100351037 cytochrome c-like
       100341175 cytochrome c
       103347723 cytochrome c-like
       100354724 cytochrome c-like
       103351673 cytochrome c-like
       108178730 cytochrome c-like
       108177422 cytochrome c-like
       103348383 APAF1; apoptotic peptidase activating factor 1
       100101592 CASP9; caspase 9
K14686 SLC31A1; solute carrier family 31 (copper transporter), member 1
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08734 MLH1; DNA mismatch repair protein MLH1
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
     01523 Antifolate resistance [PATH:ocu01523]
     01522 Endocrine resistance [PATH:ocu01522]
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
     03000 Transcription factors [BR:ocu03000]
     03021 Transcription machinery [BR:ocu03021]
     03019 Messenger RNA biogenesis [BR:ocu03019]
     03041 Spliceosome [BR:ocu03041]
     03011 Ribosome [BR:ocu03011]
     03009 Ribosome biogenesis [BR:ocu03009]
     03016 Transfer RNA biogenesis [BR:ocu03016]
     03012 Translation factors [BR:ocu03012]
     03110 Chaperones and folding catalysts [BR:ocu03110]
     04131 Membrane trafficking [BR:ocu04131]
     04121 Ubiquitin system [BR:ocu04121]
     03051 Proteasome [BR:ocu03051]
     03032 DNA replication proteins [BR:ocu03032]
     03036 Chromosome and associated proteins [BR:ocu03036]
     03400 DNA repair and recombination proteins [BR:ocu03400]
       100344525 MGMT; O-6-methylguanine-DNA methyltransferase
       100338111 ALKBH2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
       100342939 ALKBH3; alkB homolog 3, alpha-ketoglutaratedependent dioxygenase
       100339241 ASCC3; activating signal cointegrator 1 complex subunit 3
       100344454 CRY2; cryptochrome circadian clock 2
       100347047 CRY1; cryptochrome circadian clock 1
       100338366 UNG; uracil DNA glycosylase
       100346974 CCNO; cyclin O
       100355930 TDG; thymine DNA glycosylase
       100357369 MPG; N-methylpurine DNA glycosylase
       100352573 SMUG1; single-strand-selective monofunctional uracil-DNA glycosylase 1
       100344165 MUTYH; mutY DNA glycosylase
       100339392 MBD4; methyl-CpG binding domain 4, DNA glycosylase
       103345505 OGG1; 8-oxoguanine DNA glycosylase
       100358670 NEIL2; nei like DNA glycosylase 2
       100338717 NEIL3; nei like DNA glycosylase 3
       100348924 APEX1; apurinic/apyrimidinic endodeoxyribonuclease 1
       100350593 APEX2; apurinic/apyrimidinic endodeoxyribonuclease 2
       100358263 POLD2; DNA polymerase delta 2, accessory subunit
       100357626 POLD3; DNA polymerase delta 3, accessory subunit
       100356010 POLD4; DNA polymerase delta 4, accessory subunit
       100338950 POLE; DNA polymerase epsilon, catalytic subunit
       100345613 POLE2; DNA polymerase epsilon 2, accessory subunit
       100355895 POLE3; DNA polymerase epsilon 3, accessory subunit
       100358589 POLE4; DNA polymerase epsilon 4, accessory subunit
       100339381 PCNA; proliferating cell nuclear antigen
       100352966 FEN1; flap structure-specific endonuclease 1
       100340979 LIG1; DNA ligase 1
       100348691 POLB; DNA polymerase beta
       100350130 XRCC1; X-ray repair cross complementing 1
       100344941 LIG3; DNA ligase 3
       100349532 TDP1; tyrosyl-DNA phosphodiesterase 1
       103348750 aprataxin-like
       100351115 APTX; aprataxin
       100342776 APLF; aprataxin and PNKP like factor
       100328641 HMGB1; high mobility group box 1
       100358889 high mobility group protein B1
       100359149 high mobility group protein B1
       100351030 POLL; DNA polymerase lambda
       100347336 PARP1; poly(ADP-ribose) polymerase 1
       100351185 PARP2; poly(ADP-ribose) polymerase 2
       100346107 PARP4; poly(ADP-ribose) polymerase family member 4
       100344824 PARP3; poly(ADP-ribose) polymerase family member 3
       100346279 XPC; XPC complex subunit, DNA damage recognition and repair factor
       100353489 RAD23B; RAD23 homolog B, nucleotide excision repair protein
       108178685 UV excision repair protein RAD23 homolog B-like
       100350600 CETN2; centrin 2
       103352470 RBX1; ring-box 1
       100354247 CUL4A; cullin 4A
       100351102 CUL4B; cullin 4B
       100354475 DDB1; damage specific DNA binding protein 1
       100352386 DDB2; damage specific DNA binding protein 2
       100344349 POLR2A; RNA polymerase II subunit A
       100348087 POLR2B; RNA polymerase II subunit B
       100346702 POLR2C; RNA polymerase II subunit C
       100358254 POLR2D; RNA polymerase II subunit D
       100354248 POLR2F; RNA polymerase II subunit F
       100347609 POLR2G; RNA polymerase II subunit G
       100347834 POLR2H; RNA polymerase II subunit H
       100349199 POLR2I; RNA polymerase II subunit I
       108176664 POLR2L; RNA polymerase II subunit L
       100358757 POLR2J; RNA polymerase II subunit J
       108178187 DNA-directed RNA polymerases I
       108176524 POLR2K; RNA polymerase II subunit K
       100352258 ERCC8; ERCC excision repair 8, CSA ubiquitin ligase complex subunit
       100345784 ERCC6; ERCC excision repair 6, chromatin remodeling factor
       100348395 ERCC3; ERCC excision repair 3, TFIIH core complex helicase subunit
       100347957 ERCC2; ERCC excision repair 2, TFIIH core complex helicase subunit
       100342919 GTF2H1; general transcription factor IIH subunit 1
       100338745 general transcription factor IIH subunit 2
       100347110 GTF2H3; general transcription factor IIH subunit 3
       103349943 GTF2H5; general transcription factor IIH subunit 5
       100358882 CDK7; cyclin dependent kinase 7
       100358948 CCNH; cyclin H
       100349698 MNAT1; MNAT1, CDK activating kinase assembly factor
       100341460 RPA1; replication protein A1
       100347550 RPA2; replication protein A2
       100358262 RPA3; replication protein A3
       103351965 RPA4; replication protein A4
       108178030 XPA; XPA, DNA damage recognition and repair factor
       100348713 ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit
       100350642 ERCC4; ERCC excision repair 4, endonuclease catalytic subunit
       108175387 ERCC5; ERCC excision repair 5, endonuclease
       100347339 MMS19; MMS19 homolog, cytosolic iron-sulfur assembly component
       100338738 CUL3; cullin 3
       100009207 CUL5; cullin 5
       100341083 ELOC; elongin C
       100355441 transcription elongation factor B polypeptide 1-like
       100340879 ELOB; elongin B
       100357661 ELOA; elongin A
       100339926 transcription elongation factor B polypeptide 3
       100354413 transcription elongation factor B polypeptide 3-like
       103347805 MSH2; mutS homolog 2
       100337807 MSH3; mutS homolog 3
       100351645 MSH6; mutS homolog 6
       100345599 MSH4; mutS homolog 4
       100352507 MSH5; mutS homolog 5
       100342037 PMS1; PMS1 homolog 1, mismatch repair system component
       100337912 MLH1; mutL homolog 1
       100355997 PMS2; PMS1 homolog 2, mismatch repair system component
       100339094 MLH3; mutL homolog 3
       100352565 RFC1; replication factor C subunit 1
       100343517 RFC2; replication factor C subunit 2
       100342140 RFC4; replication factor C subunit 4
       100339186 RFC3; replication factor C subunit 3
       100345366 RFC5; replication factor C subunit 5
       100338764 EXO1; exonuclease 1
       100328690 WDR76; WD repeat domain 76
       100356946 MRE11; MRE11 homolog, double strand break repair nuclease
       100328725 RAD50; RAD50 double strand break repair protein
       100352398 NBN; nibrin
       100347269 BRCA1; BRCA1, DNA repair associated
       100340914 BARD1; BRCA1 associated RING domain 1
       100350582 FAM175A; family with sequence similarity 175 member A
       100354766 UIMC1; ubiquitin interaction motif containing 1
       100347469 BRE; brain and reproductive organ-expressed (TNFRSF1A modulator)
       100339276 BRCC3; BRCA1/BRCA2-containing complex subunit 3
       100359326 BRIP1; BRCA1 interacting protein C-terminal helicase 1
       100349197 TOPBP1; topoisomerase (DNA) II binding protein 1
       100353053 DNA endonuclease RBBP8-like
       100354690 RBBP8; RB binding protein 8, endonuclease
       100355331 BRCA2; BRCA2, DNA repair associated
       100356031 PALB2; partner and localizer of BRCA2
       100008661 RAD51; RAD51 recombinase
       100351948 RAD51B; RAD51 paralog B
       100339674 RAD51C; RAD51 paralog C
       100357424 RAD51D; RAD51 paralog D
       100342809 XRCC2; X-ray repair cross complementing 2
       100354479 XRCC3; X-ray repair cross complementing 3
       100338134 DMC1; DNA meiotic recombinase 1
       100350648 RAD52; RAD52 homolog, DNA repair protein
       100342481 RDM1; RAD52 motif containing 1
       100340671 RAD54L; RAD54-like (S. cerevisiae)
       100343308 RAD54L2; RAD54-like 2 (S. cerevisiae)
       100354266 RAD54B; RAD54 homolog B (S. cerevisiae)
       100341857 RECQL; RecQ like helicase
       100341925 WRN; Werner syndrome RecQ like helicase
       100345123 BLM; Bloom syndrome RecQ like helicase
       100341996 RECQL5; RecQ like helicase 5
       100338026 TOP3A; topoisomerase (DNA) III alpha
       100345272 TOP3B; topoisomerase (DNA) III beta
       100352297 RMI1; RecQ mediated genome instability 1
       100348643 RMI2; RecQ mediated genome instability 2
       100009163 PPP4C; protein phosphatase 4 catalytic subunit
       100354033 PPP4R1; protein phosphatase 4 regulatory subunit 1
       100352584 PPP4R2; protein phosphatase 4 regulatory subunit 2
       100345999 PPP4R3B; protein phosphatase 4 regulatory subunit 3B
       100347843 PPP4R3A; protein phosphatase 4 regulatory subunit 3A
       100357964 PPP4R4; protein phosphatase 4 regulatory subunit 4
       100341073 AP5B1; adaptor related protein complex 5 beta 1 subunit
       100358901 AP5M1; adaptor related protein complex 5 mu 1 subunit
       100347137 AP5S1; adaptor related protein complex 5 sigma 1 subunit
       100353386 AP5Z1; adaptor related protein complex 5 zeta 1 subunit
       100358575 SMC5; structural maintenance of chromosomes 5
       100354764 SMC6; structural maintenance of chromosomes 6
       100340991 FAM84A; family with sequence similarity 84 member A
       100359125 NSMCE1; NSE1 homolog, SMC5-SMC6 complex component
       100356538 NSMCE2; NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
       100345871 NSMCE3; NSE3 homolog, SMC5-SMC6 complex component
       100356831 NSMCE4A; NSE4 homolog A, SMC5-SMC6 complex component
       100349362 SYCP2; synaptonemal complex protein 2
       103348357 SYCP3; synaptonemal complex protein 3
       100341377 EME1; essential meiotic structure-specific endonuclease 1
       100348519 EXD2; exonuclease 3'-5' domain containing 2
       100343911 HFM1; HFM1, ATP dependent DNA helicase homolog
       100341582 MUS81; MUS81 structure-specific endonuclease subunit
       108178368 26S proteasome complex subunit DSS1
       100359270 SPO11; SPO11, initiator of meiotic double stranded breaks
       108178495 C1H11orf80; chromosome 1 open reading frame, human C11orf80
       103348603 SLX1A; SLX1 homolog A, structure-specific endonuclease subunit
       100347540 SLX4; SLX4 structure-specific endonuclease subunit
       100355273 GEN1; GEN1, Holliday junction 5' flap endonuclease
       100357157 SPG11; spastic paraplegia 11 (autosomal recessive)
       100353465 ZFYVE26; zinc finger FYVE-type containing 26
       100343305 RAD51AP1; RAD51 associated protein 1
       100340614 MORF4L1; mortality factor 4 like 1
       100345655 MEIOB; meiosis specific with OB domains
       100353117 SPATA22; spermatogenesis associated 22
       100353160 SAMHD1; SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
       100356925 FIGNL1; fidgetin like 1
       100348975 SPIDR; scaffolding protein involved in DNA repair
       100357048 FAM84B; family with sequence similarity 84 member B
       103346583 BRAT1; BRCA1 associated ATM activator 1
       100351956 XRCC6; X-ray repair cross complementing 6
       100347656 XRCC5; X-ray repair cross complementing 5
       100125348 PRKDC; protein kinase, DNA-activated, catalytic polypeptide
       100340318 LIG4; DNA ligase 4
       100355796 XRCC4; X-ray repair cross complementing 4
       100353092 NHEJ1; non-homologous end joining factor 1
       100358003 POLM; DNA polymerase mu
       100353958 DNTT; DNA nucleotidylexotransferase
       100349686 DCLRE1C; DNA cross-link repair 1C
       100351584 TDP2; tyrosyl-DNA phosphodiesterase 2
       100348571 SMCHD1; structural maintenance of chromosomes flexible hinge domain containing 1
       100340790 MUM1L1; MUM1 like 1
       100353147 titin
       100340806 FANCA; Fanconi anemia complementation group A
       100355151 FANCB; Fanconi anemia complementation group B
       100344788 FANCC; Fanconi anemia complementation group C
       100359053 FANCE; Fanconi anemia complementation group E
       100340638 FANCF; Fanconi anemia complementation group F
       100346331 FANCG; Fanconi anemia complementation group G
       100344973 FANCL; Fanconi anemia complementation group L
       100354209 FANCM; Fanconi anemia complementation group M
       100357310 FAAP24; Fanconi anemia core complex associated protein 24
       108176186 Fanconi anemia core complex-associated protein 100-like
       100358704 HES1; hes family bHLH transcription factor 1
       100534620 CENPS; centromere protein S
       100354742 CENPX; centromere protein X
       100357338 UBE2T; ubiquitin conjugating enzyme E2 T
       100346581 FANCD2; Fanconi anemia complementation group D2
       100347941 FANCI; Fanconi anemia complementation group I
       100345357 FAN1; FANCD2 and FANCI associated nuclease 1
       100356602 TELO2; telomere maintenance 2
       100358366 USP1; ubiquitin specific peptidase 1
       100354945 WDR48; WD repeat domain 48
       100341981 PPP6C; protein phosphatase 6 catalytic subunit
       100354502 PPP6R1; protein phosphatase 6 regulatory subunit 1
       100352630 PPP6R2; protein phosphatase 6 regulatory subunit 2
       100338706 PPP6R3; protein phosphatase 6 regulatory subunit 3
       100343070 ANKRD28; ankyrin repeat domain 28
       100340911 ANKRD44; ankyrin repeat domain 44
       100350556 ANKRD52; ankyrin repeat domain 52
       100343659 RNF8; ring finger protein 8
       100348840 RNF168; ring finger protein 168
       100356853 RNF169; ring finger protein 169
       100340267 E3 ubiquitin-protein ligase HERC2
       100343593 WRAP53; WD repeat containing antisense to TP53
       100339809 ZCWPW1; zinc finger CW-type and PWWP domain containing 1
       100348233 WDR70; WD repeat domain 70
       100357494 POLH; DNA polymerase eta
       100342545 POLI; DNA polymerase iota
       100352218 POLK; DNA polymerase kappa
       100345920 REV1; REV1, DNA directed polymerase
       100359215 REV3L; REV3 like, DNA directed polymerase zeta catalytic subunit
       100349293 POLN; DNA polymerase nu
       100339096 UBE2A; ubiquitin conjugating enzyme E2 A
       100009132 UBE2B; ubiquitin conjugating enzyme E2 B
       100345274 RAD18; RAD18, E3 ubiquitin protein ligase
       100009232 HLTF; helicase like transcription factor
       108177259 ubiquitin-conjugating enzyme E2 variant 1-like
       100352653 UBE2V2; ubiquitin conjugating enzyme E2 V2
       100350804 UBE2V1; ubiquitin conjugating enzyme E2 V1
       100344152 ubiquitin-conjugating enzyme E2 variant 2
       100339349 ubiquitin-conjugating enzyme E2 N-like
       100343655 ubiquitin-conjugating enzyme E2 N
       100353764 UBE2N; ubiquitin conjugating enzyme E2 N
       100341684 ubiquitin-conjugating enzyme E2 N-like
       100349507 ARMT1; acidic residue methyltransferase 1
       100351432 SPRTN; SprT-like N-terminal domain
       100356526 RAD9A; RAD9 checkpoint clamp component A
       100358383 RAD9B; RAD9 checkpoint clamp component B
       100357438 HUS1; HUS1 checkpoint clamp component
       100354386 HUS1B; HUS1 checkpoint clamp component B
       100351835 RAD1; RAD1 checkpoint DNA exonuclease
       100339735 RAD17; RAD17 checkpoint clamp loader component
       100345229 TIMELESS; timeless circadian clock
       100348340 TIPIN; TIMELESS interacting protein
       100352399 TTI1; TELO2 interacting protein 1
       100358152 TTI2; TELO2 interacting protein 2
       100350337 BAG6; BCL2 associated athanogene 6
       100328764 UBL4A; ubiquitin like 4A
       100338070 UBL4B; ubiquitin like 4B
       100359062 ATR; ATR serine/threonine kinase
       100355293 ATRIP; ATR interacting protein
       100349299 ATM; ATM serine/threonine kinase
       100009292 TP53; tumor protein p53
       100345729 CHEK1; checkpoint kinase 1
       100339430 CHEK2; checkpoint kinase 2
       100354280 CDC25A; cell division cycle 25A
       103348219 CDC25B; cell division cycle 25B
       100343637 CDC25C; cell division cycle 25C
       100358299 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
       100008930 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
       100342694 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
       100328734 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
       100354276 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
       100358813 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
       100352991 NAV2; neuron navigator 2
       100356408 WEE2; WEE1 homolog 2
       100345730 WEE1; WEE1 G2 checkpoint kinase
       100342071 PER1; period circadian clock 1
       100349720 PER2; period circadian clock 2
       100351506 MDC1; mediator of DNA damage checkpoint 1
       100345115 PLS3; plastin 3
       103347192 AEN; apoptosis enhancing nuclease
       100349159 PLK3; polo like kinase 3
       100349662 NEK4; NIMA related kinase 4
       100346687 NEK1; NIMA related kinase 1
       100345120 NEK5; NIMA related kinase 5
       100340252 NEK10; NIMA related kinase 10
       100339160 NEK11; NIMA related kinase 11
       100357779 DONSON; downstream neighbor of SON
       100358626 KANK4; KN motif and ankyrin repeat domains 4
       100358825 KANK3; KN motif and ankyrin repeat domains 3
       103348186 KANK1; KN motif and ankyrin repeat domains 1
       100357938 SLFN13; schlafen family member 13
       100347474 CHMP4C; charged multivesicular body protein 4C
       100338152 VPS4B; vacuolar protein sorting 4 homolog B
       100340140 VPS4A; vacuolar protein sorting 4 homolog A
       100345353 ZFYVE19; zinc finger FYVE-type containing 19
       100341958 POLQ; DNA polymerase theta
       100349437 MYBBP1A; MYB binding protein 1a
       100342519 PRIMPOL; primase and DNA directed polymerase
       100355546 TREX1; three prime repair exonuclease 1
       100357277 TREX2; three prime repair exonuclease 2
       100359072 DCLRE1A; DNA cross-link repair 1A
       100354044 DCLRE1B; DNA cross-link repair 1B
       100338162 EXO5; exonuclease 5
       100357722 ENDOV; endonuclease V
       100349596 HELQ; helicase, POLQ-like
       100345815 ERCC6L2; ERCC excision repair 6 like 2
       100358501 PRPF19; pre-mRNA processing factor 19
       100340843 CDC5L; cell division cycle 5 like
       100345435 BCAS2; BCAS2, pre-mRNA processing factor
       100350581 PLRG1; pleiotropic regulator 1
       100356660 NUDT15; nudix hydrolase 15
       100348373 NUDT1; nudix hydrolase 1
       100357274 NUDT18; nudix hydrolase 18
       100346219 deoxyuridine 5'-triphosphate nucleotidohydrolase
       100341806 DUT; deoxyuridine triphosphatase
       100345823 RRM1; ribonucleotide reductase catalytic subunit M1
       100346325 RRM2; ribonucleotide reductase regulatory subunit M2
       100337711 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
       100008866 SSBP1; single stranded DNA binding protein 1
K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:3.6.4.12]
K02295 CRY; cryptochrome
K02295 CRY; cryptochrome
K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
K10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]
K10569 NEIL3; endonuclease VIII-like 3
K10771 APEX1; AP endonuclease 1 [EC:4.2.99.18]
K10772 APEX2; AP endonuclease 2 [EC:4.2.99.18]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K04802 PCNA; proliferating cell nuclear antigen
K04799 FEN1; flap endonuclease-1 [EC:3.-.-.-]
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K10803 XRCC1; DNA-repair protein XRCC1
K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
K13295 APLF; aprataxin and PNK-like factor [EC:4.2.99.18]
K10802 HMGB1; high mobility group protein B1
K10802 HMGB1; high mobility group protein B1
K10802 HMGB1; high mobility group protein B1
K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10838 XPC; xeroderma pigmentosum group C-complementing protein
K10839 RAD23; UV excision repair protein RAD23
K10839 RAD23; UV excision repair protein RAD23
K10840 CETN2; centrin-2
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K10609 CUL4; cullin 4
K10609 CUL4; cullin 4
K10610 DDB1; DNA damage-binding protein 1
K10140 DDB2; DNA damage-binding protein 2
K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
K03014 RPB6; DNA-directed RNA polymerases I, II, and III subunit RPABC2
K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
K03016 RPB8; DNA-directed RNA polymerases I, II, and III subunit RPABC3
K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
K03007 RPB10; DNA-directed RNA polymerases I, II, and III subunit RPABC5
K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
K03009 RPB12; DNA-directed RNA polymerases I, II, and III subunit RPABC4
K03009 RPB12; DNA-directed RNA polymerases I, II, and III subunit RPABC4
K10570 ERCC8; DNA excision repair protein ERCC-8
K10841 ERCC6; DNA excision repair protein ERCC-6
K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:3.6.4.12]
K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:3.6.4.12]
K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K06634 CCNH; cyclin H
K10842 MNAT1; CDK-activating kinase assembly factor MAT1
K07466 RFA1; replication factor A1
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K10741 RPA4; replication factor A4
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K10846 ERCC5; DNA excision repair protein ERCC-5
K15075 MET18; DNA repair/transcription protein MET18/MMS19
K03869 CUL3; cullin 3
K10612 CUL5; cullin 5
K03872 ELOC; elongin-C
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K15076 ELOA; elongin-A
K15076 ELOA; elongin-A
K15076 ELOA; elongin-A
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08740 MSH4; DNA mismatch repair protein MSH4
K08741 MSH5; DNA mismatch repair protein MSH5
K10864 PMS1; DNA mismatch repair protein PMS1
K08734 MLH1; DNA mismatch repair protein MLH1
K10858 PMS2; DNA mismatch repair protein PMS2
K08739 MLH3; DNA mismatch repair protein MLH3
K10754 RFC1; replication factor C subunit 1
K10755 RFC2_4; replication factor C subunit 2/4
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K10756 RFC3_5; replication factor C subunit 3/5
K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
K24755 WDR76; WD repeat-containing protein 76
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K10683 BARD1; BRCA1-associated RING domain protein 1
K20774 FAM175A; BRCA1-A complex subunit Abraxas
K20775 UIMC1; BRCA1-A complex subunit RAP80
K12173 BRE; BRCA1-A complex subunit BRE
K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
K15362 BRIP1; fanconi anemia group J protein [EC:3.6.4.12]
K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]
K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]
K08775 BRCA2; breast cancer 2 susceptibility protein
K10897 PALB2; partner and localizer of BRCA2
K04482 RAD51; DNA repair protein RAD51
K10869 RAD51L1; RAD51-like protein 1
K10870 RAD51L2; RAD51-like protein 2
K10871 RAD51L3; RAD51-like protein 3
K10879 XRCC2; DNA-repair protein XRCC2
K10880 XRCC3; DNA-repair protein XRCC3
K10872 DMC1; meiotic recombination protein DMC1
K10873 RAD52; DNA repair and recombination protein RAD52
K10874 RDM1; RAD52 motif-containing protein 1
K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:3.6.4.-]
K10876 RAD54L2; RAD54-like protein 2 [EC:3.6.4.12]
K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:3.6.4.-]
K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:3.6.4.12]
K10900 WRN; werner syndrome ATP-dependent helicase [EC:3.6.4.12]
K10901 BLM; bloom syndrome protein [EC:3.6.4.12]
K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:3.6.4.12]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K10990 RMI1; RecQ-mediated genome instability protein 1
K15365 RMI2; RecQ-mediated genome instability protein 2
K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
K19022 AP5B1; AP-5 complex subunit beta-1
K19023 AP5M1; AP-5 complex subunit mu-1
K19024 AP5S1; AP-5 complex subunit sigma-1
K19025 AP5Z1; AP-5 complex subunit zeta-1
K22803 SMC5; structural maintenance of chromosomes protein 5
K22804 SMC6; structural maintenance of chromosomes protein 6
K22805 FAM84A; protein FAM84A
K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
K22823 NSMCE3; non-structural maintenance of chromosomes element 3
K22825 NSMCE4; non-structural maintenance of chromosomes element 4
K19529 SYCP2; synaptonemal complex protein 2
K19528 SYCP3; synaptonemal complex protein 3
K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
K15271 HFM1; ATP-dependent DNA helicase HFM1/MER3 [EC:3.6.4.12]
K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
K10881 SHFM1; 26 proteasome complex subunit DSS1
K10878 SPO11; meiotic recombination protein SPO11
 
K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
K15338 GEN1; flap endonuclease GEN [EC:3.1.-.-]
K19026 SPG11; spatacsin
K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
K20778 RAD51AP1; RAD51-associated protein 1
K11339 MORF4L1; mortality factor 4-like protein 1
K22420 MEIOB; meiosis-specific with OB domain-containing protein [EC:3.1.-.-]
K22421 SPATA22; spermatogenesis-associated protein 22
K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
K22766 FIGNL1; fidgetin-like protein 1 [EC:3.6.4.-]
K22806 SPIDR; DNA repair-scaffolding protein
K22810 FAM84B; protein FAM84B
K23112 BRAT1; BRCA1-associated ATM activator 1
K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
K10886 XRCC4; DNA-repair protein XRCC4
K10980 NHEJ1; non-homologous end-joining factor 1
K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
K23386 PWWP3; PWWP domain-containing DNA repair factor 3
K23386 PWWP3; PWWP domain-containing DNA repair factor 3
K10888 FANCA; fanconi anemia group A protein
K10889 FANCB; fanconi anemia group B protein
K10890 FANCC; fanconi anemia group C protein
K10892 FANCE; fanconi anemia group E protein
K10893 FANCF; fanconi anemia group F protein
K10894 FANCG; fanconi anemia group G protein
K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
K10896 FANCM; fanconi anemia group M protein
K10898 FAAP24; fanconi anemia-associated protein
K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
K06054 HES1; hairy and enhancer of split 1
K11511 APITD1; centromere protein S
K15360 STRA13; centromere protein X
K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
K10891 FANCD2; fanconi anemia group D2 protein
K10895 FANCI; fanconi anemia group I protein
K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
K11137 TELO2; telomere length regulation protein
K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
K15361 WDR48; WD repeat-containing protein 48
K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
K15499 PPP6R1; serine/threonine-protein phosphatase 6 regulatory subunit 1
K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
K23314 WRAP53; telomerase Cajal body protein 1
K24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1
K24752 WDR70; WD repeat-containing protein 70
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:3.6.4.- 2.3.2.27]
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K23114 ARMT1; protein-glutamate O-methyltransferase [EC:2.1.1.-]
K24051 SPRTN; SprT-like domain-contaning protein Spartan
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K10903 HUS1; HUS1 checkpoint protein
K10996 HUS1B; checkpoint protein HUS1B
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K06662 HRAD17; cell cycle checkpoint protein
K03155 TIMELESS; timeless
K10904 TIPIN; TIMELESS-interacting protein
K20403 TTI1; TELO2-interacting protein 1
K23115 TTI2; TELO2-interacting protein 2
K23390 BAG6; large proline-rich protein BAG6
K23388 UBL4; ubiquitin-like protein 4
K23388 UBL4; ubiquitin-like protein 4
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K10905 ATRIP; ATR interacting protein
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06630 YWHAE; 14-3-3 protein epsilon
K19483 NAV2; neuron navigator 2 [EC:3.6.4.12]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K21944 PER1; period circadian protein 1
K02633 PER2; period circadian protein 2
K20780 MDC1; mediator of DNA damage checkpoint protein 1
K17336 PLS3; plastin-3
K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08857 NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]
K08857 NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]
K08857 NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]
K20879 NEK10; NIMA (never in mitosis gene a)-related kinase 10 [EC:2.7.11.1]
K20880 NEK11; NIMA (never in mitosis gene a)-related kinase 11 [EC:2.7.11.1]
K22422 DONSON; protein downstream neighbor of Son
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K24458 SLFN11; schlafen family member 11 [EC:3.6.-.-]
K24782 CHMP4C; charged multivesicular body protein 4C
K12196 VPS4; vacuolar protein-sorting-associated protein 4
K12196 VPS4; vacuolar protein-sorting-associated protein 4
K24778 ZFYVE19; abscission/NoCut checkpoint regulator
K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
K10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]
K15340 DCLRE1A; DNA cross-link repair 1A protein
K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
K17815 EXO5; exonuclease V [EC:3.1.-.-]
K21813 ENDOV; endonuclease V [EC:3.1.26.-]
K19178 HELQ; POLQ-like helicase [EC:3.6.4.12]
K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:3.6.4.-]
K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
K12861 BCAS2; pre-mRNA-splicing factor SPF27
K12862 PLRG1; pleiotropic regulator 1
K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
K01520 dut; dUTP pyrophosphatase [EC:3.6.1.23]
K01520 dut; dUTP pyrophosphatase [EC:3.6.1.23]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K03111 ssb; single-strand DNA-binding protein
     03029 Mitochondrial biogenesis [BR:ocu03029]
 
   09183 Protein families: signaling and cellular processes
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: March 5, 2021