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KO |
Eukaryotic type
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Sister chromatid cohesion proteins
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Meiosis-specific proteins
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Nucleosome assembly factors
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Histone modification proteins
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HATs (histone acetyltransferases)
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HAT complexes
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HDACs (histone deacetylases)
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HDAC complexes
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HMTs (histone methyltransferases)
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HKMTs (histone lysine methyltransferases)
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101156847 ash1l; histone-lysine N-methyltransferase ASH1L isoform X1
101161417 histone-lysine N-methyltransferase ASH1L isoform X2
101166952 dot1l; histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
101171173 histone-lysine N-methyltransferase EHMT1 isoform X1
101167635 histone-lysine N-methyltransferase EHMT1 isoform X1
101167716 ehmt2; histone-lysine N-methyltransferase EHMT2
101166385 ezh1; histone-lysine N-methyltransferase EZH1
100125823 ezh2; histone-lysine N-methyltransferase EZH2
101171020 kmt2a; histone-lysine N-methyltransferase 2A isoform X1
101172242 kmt2d; histone-lysine N-methyltransferase 2D isoform X1
101162786 histone-lysine N-methyltransferase 2C isoform X1
101171448 histone-lysine N-methyltransferase 2C isoform X1
101174945 kmt2b; histone-lysine N-methyltransferase 2B isoform X1
101157226 histone-lysine N-methyltransferase 2B
101162568 kmt2e; histone-lysine N-methyltransferase 2E isoform X1
101160669 histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific
101161079 histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific isoform X2
101172132 nsd2; histone-lysine N-methyltransferase NSD2
101156018 nsd3; histone-lysine N-methyltransferase NSD3 isoform X1
101156736 PR domain zinc finger protein 2
101157610 prdm2; PR domain zinc finger protein 2 isoform X1
101169474 mecom; MDS1 and EVI1 complex locus protein EVI1 isoform X1
105354834 prdm6; putative histone-lysine N-methyltransferase PRDM6
101168249 histone-lysine N-methyltransferase PRDM9
101160915 prdm8; PR domain zinc finger protein 8
101164500 PR domain zinc finger protein 8 isoform X2
101159281 prdm12; PR domain zinc finger protein 12
101172909 PR domain zinc finger protein 12
101156011 prdm16; PR domain zinc finger protein 16 isoform X1
101168786 histone-lysine N-methyltransferase SETD1A
101162384 setd1b; histone-lysine N-methyltransferase SETD1B isoform X1
101163764 setd2; histone-lysine N-methyltransferase SETD2 isoform X1
101154890 setd4; SET domain-containing protein 4 isoform X1
101166221 setd6; N-lysine methyltransferase SETD6
101168630 setd7; histone-lysine N-methyltransferase SETD7
101172663 N-lysine methyltransferase KMT5A isoform X4
101169793 kmt5a; N-lysine methyltransferase KMT5A isoform X1
101158302 setdb1; histone-lysine N-methyltransferase SETDB1
101163233 histone-lysine N-methyltransferase SETDB2 isoform X1
101172575 histone-lysine N-methyltransferase SETMAR
101169349 smyd3; histone-lysine N-methyltransferase SMYD3
101161247 histone-lysine N-methyltransferase SMYD1 isoform X2
101164768 smyd2; N-lysine methyltransferase SMYD2 isoform X1
101173073 histone-lysine N-methyltransferase Smyd1
101159335 N-lysine methyltransferase SMYD2-A
101155408 suv39h1; histone-lysine N-methyltransferase SUV39H1 isoform X1
101165555 uncharacterized protein LOC101165555
101156070 kmt5b; histone-lysine N-methyltransferase KMT5B isoform X1
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K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
K09187 MLL2; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354]
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
K11424 WHSC1; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357]
K11425 WHSC1L1; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371]
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361]
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-]
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-]
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359]
K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364]
K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355]
K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
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PRMTs (protein arginine metyltransferases)
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HMT complexes
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COMPASS/SET1 complex
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101168786 histone-lysine N-methyltransferase SETD1A
101162384 setd1b; histone-lysine N-methyltransferase SETD1B isoform X1
101158437 cxxc1; CXXC-type zinc finger protein 1 isoform X1
101175046 CXXC-type zinc finger protein 1 isoform X1
101164873 rbbp5; retinoblastoma-binding protein 5 isoform X1
101173843 WD repeat-containing protein 82
110015105 wdr82; WD repeat-containing protein 82
101166483 wdr5; WD repeat-containing protein 5
101168557 ash2l; set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1
101157935 hcfc1; host cell factor 1
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K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K14960 CXXC1; COMPASS component SPP1
K14960 CXXC1; COMPASS component SPP1
K14961 RBBP5; COMPASS component SWD1
K14962 WDR82; COMPASS component SWD2
K14962 WDR82; COMPASS component SWD2
K14963 WDR5; COMPASS component SWD3
K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
K14966 HCFC1; host cell factor 1
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COMPASS/SET1 complex (yeast)
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101168786 histone-lysine N-methyltransferase SETD1A
101162384 setd1b; histone-lysine N-methyltransferase SETD1B isoform X1
101158437 cxxc1; CXXC-type zinc finger protein 1 isoform X1
101175046 CXXC-type zinc finger protein 1 isoform X1
101164873 rbbp5; retinoblastoma-binding protein 5 isoform X1
101173843 WD repeat-containing protein 82
110015105 wdr82; WD repeat-containing protein 82
101166483 wdr5; WD repeat-containing protein 5
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K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K14960 CXXC1; COMPASS component SPP1
K14960 CXXC1; COMPASS component SPP1
K14961 RBBP5; COMPASS component SWD1
K14962 WDR82; COMPASS component SWD2
K14962 WDR82; COMPASS component SWD2
K14963 WDR5; COMPASS component SWD3
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MLL-HCF complex
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MLL3/MLL4 complex
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Dot1-containing complex
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Histone demethylases
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Polycomb repressive complex (PRC) and associated proteins
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Sir proteins
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Other histone modification proteins
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Chromosome condensation proteins
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Centromeric chromatin formation proteins
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Heterochromatin formation proteins
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Gene silencing
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Centrosome formation proteins
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Sister chromatid separation proteins
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Chromatin remodeling factors
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Prokaryotic type
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