KEGG Orthology (KO) - Pongo abelii (Sumatran orangutan)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
   09151 Immune system
     04640 Hematopoietic cell lineage [PATH:pon04640]
     04610 Complement and coagulation cascades [PATH:pon04610]
     04611 Platelet activation [PATH:pon04611]
     04613 Neutrophil extracellular trap formation [PATH:pon04613]
     04620 Toll-like receptor signaling pathway [PATH:pon04620]
     04624 Toll and Imd signaling pathway
     04621 NOD-like receptor signaling pathway [PATH:pon04621]
     04622 RIG-I-like receptor signaling pathway [PATH:pon04622]
     04623 Cytosolic DNA-sensing pathway [PATH:pon04623]
     04625 C-type lectin receptor signaling pathway [PATH:pon04625]
     04650 Natural killer cell mediated cytotoxicity [PATH:pon04650]
     04612 Antigen processing and presentation [PATH:pon04612]
     04660 T cell receptor signaling pathway [PATH:pon04660]
     04658 Th1 and Th2 cell differentiation [PATH:pon04658]
     04659 Th17 cell differentiation [PATH:pon04659]
     04657 IL-17 signaling pathway [PATH:pon04657]
     04662 B cell receptor signaling pathway [PATH:pon04662]
     04664 Fc epsilon RI signaling pathway [PATH:pon04664]
     04666 Fc gamma R-mediated phagocytosis [PATH:pon04666]
       100939231 uncharacterized protein LOC100939231
       100939054 immunoglobulin alpha-2 heavy chain-like
       100939294 uncharacterized protein LOC100939294
       100431520 immunoglobulin delta heavy chain-like
       100431914 high affinity immunoglobulin gamma Fc receptor I isoform X2
       100455333 FCGR2A; low affinity immunoglobulin gamma Fc region receptor II-a isoform X1
       100453994 low affinity immunoglobulin gamma Fc region receptor III-A isoform X1
       100446144 PTPRC; receptor-type tyrosine-protein phosphatase C isoform X1
       100455620 HCK; tyrosine-protein kinase HCK
       100447326 LYN; tyrosine-protein kinase Lyn isoform X1
       100438875 SYK; tyrosine-protein kinase SYK isoform X1
       100432846 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100453779 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       103889133 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       100174298 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       100173589 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
       100437617 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100454279 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
       100448114 AKT3; RAC-gamma serine/threonine-protein kinase
       100442100 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
       100462008 LOW QUALITY PROTEIN: ribosomal protein S6 kinase beta-1
       100459428 RPS6KB2; ribosomal protein S6 kinase beta-2
       100456988 RPS6KB1; LOW QUALITY PROTEIN: ribosomal protein S6 kinase beta-1
       100450941 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2
       100457650 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       100452668 PRKCD; protein kinase C delta type isoform X1
       100440778 PRKCE; protein kinase C epsilon type
       100173732 RAF1; RAF proto-oncogene serine/threonine-protein kinase
       100446021 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       100169740 MAPK1; mitogen-activated protein kinase 1 isoform X1
       100431824 MAPK3; LOW QUALITY PROTEIN: mitogen-activated protein kinase 3
       100454614 PLA2G4E; cytosolic phospholipase A2 epsilon
       100173125 PLA2G4A; cytosolic phospholipase A2
       100447631 PLA2G4B; cytosolic phospholipase A2 beta
       100434495 PLA2G4C; cytosolic phospholipase A2 gamma isoform X3
       100454977 PLA2G4D; cytosolic phospholipase A2 delta
       100448616 PLA2G4F; cytosolic phospholipase A2 zeta
       100445065 PLA2G6; 85/88 kDa calcium-independent phospholipase A2 isoform X2
       100445187 MARCKS; myristoylated alanine-rich C-kinase substrate
       100434835 MARCKSL1; MARCKS-related protein
       100439813 PLD1; phospholipase D1 isoform X1
       100457163 PLD2; phospholipase D2
       100442989 PLPP2; phospholipid phosphatase 2 isoform X1
       100448168 PLPP1; phospholipid phosphatase 1 isoform X1
       100455097 PLPP3; phospholipid phosphatase 3
       100433232 SPHK1; sphingosine kinase 1 isoform X1
       100172513 SPHK2; sphingosine kinase 2
       100434355 PRKCA; protein kinase C alpha type isoform X1
       100439900 PRKCB; protein kinase C beta type isoform X2
       100451563 PRKCG; protein kinase C gamma type
       100442050 NCF1; neutrophil cytosol factor 1
       100172865 GSN; gelsolin
       100441440 SCIN; adseverin isoform X1
       100442703 VAV3; guanine nucleotide exchange factor VAV3
       100171723 VAV2; guanine nucleotide exchange factor VAV2
       100447155 VAV1; proto-oncogene vav isoform X1
       100438199 CDC42; cell division control protein 42 homolog
       100452449 WAS; LOW QUALITY PROTEIN: wiskott-Aldrich syndrome protein
       100462324 VASP; vasodilator-stimulated phosphoprotein isoform X1
       100173969 ACTR2; actin-related protein 2
       100454564 ACTR3B; LOW QUALITY PROTEIN: actin-related protein 3B
       100173023 ACTR3; actin-related protein 3
       100461245 ARPC1A; actin-related protein 2/3 complex subunit 1A
       100458060 ARPC1B; actin-related protein 2/3 complex subunit 1B
       100173646 ARPC2; actin-related protein 2/3 complex subunit 2
       100460433 ARPC3; actin-related protein 2/3 complex subunit 3
       100936009 ARPC4; actin-related protein 2/3 complex subunit 4 isoform X1
       100173958 ARPC5L; actin-related protein 2/3 complex subunit 5-like protein
       100174767 ARPC5; actin-related protein 2/3 complex subunit 5
       100443271 RAC1; ras-related C3 botulinum toxin substrate 1
       100431483 RAC2; ras-related C3 botulinum toxin substrate 2
       100174148 WASF1; wiskott-Aldrich syndrome protein family member 1
       100437132 LOW QUALITY PROTEIN: wiskott-Aldrich syndrome protein family member 2-like
       100447501 WASF2; wiskott-Aldrich syndrome protein family member 2
       100445243 WASF3; wiskott-Aldrich syndrome protein family member 3 isoform X1
       100449316 PAK1; serine/threonine-protein kinase PAK 1 isoform X1
       100432626 LIMK1; LIM domain kinase 1
       100460494 LIMK2; LIM domain kinase 2 isoform X1
       100454363 CFL2; cofilin-2 isoform X1
       103891788 CFL1; cofilin-1 isoform X1
       100456775 PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X3
       100432274 PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta
       100435603 PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1
       100443776 putative PIP5K1A and PSMD4-like protein
       100444466 phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1
       100432444 ARF6; ADP-ribosylation factor 6
       100452410 CRK; adapter molecule crk isoform X1
       100443298 CRKL; crk-like protein
       100462022 DOCK1; dedicator of cytokinesis protein 1 isoform X1
       100460279 ASAP1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1
       100458725 ASAP3; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X1
       100440164 ASAP2; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform X1
       100453137 FCGR2B; low affinity immunoglobulin gamma Fc region receptor II-b isoform X3
       100446045 INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
       100450015 INPPL1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1
       100457376 GAB2; GRB2-associated-binding protein 2
       100453027 LAT; linker for activation of T-cells family member 1 isoform X2
       100442734 DNM2; dynamin-2 isoform X1
       100446471 AMPH; amphiphysin
       103889932 BIN1; myc box-dependent-interacting protein 1 isoform X3
       100432603 MYO10; unconventional myosin-X isoform X1
K06856 IGH; immunoglobulin heavy chain
K06856 IGH; immunoglobulin heavy chain
K06856 IGH; immunoglobulin heavy chain
K06856 IGH; immunoglobulin heavy chain
K06498 FCGR1A; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A; low affinity immunoglobulin gamma Fc receptor II-a
K06463 FCGR3; low affinity immunoglobulin gamma Fc receptor III
K06478 PTPRC; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
K12561 MARCKS; myristoylated alanine-rich C-kinase substrate
K13536 MARCKSL1; MARCKS-related protein
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K08011 NCF1; neutrophil cytosolic factor 1
K05768 GSN; gelsolin
K05768 GSN; gelsolin
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K04393 CDC42; cell division control protein 42
K05747 WAS; Wiskott-Aldrich syndrome protein
K06274 VASP; vasodilator-stimulated phosphoprotein
K17260 ACTR2; actin-related protein 2
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K05753 WASF1; WAS protein family, member 1
K05748 WASF2; WAS protein family, member 2
K05748 WASF2; WAS protein family, member 2
K06083 WASF3; WAS protein family, member 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05765 CFL; cofilin
K05765 CFL; cofilin
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K07941 ARF6; ADP-ribosylation factor 6
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
K12560 FCGR2B; low affinity immunoglobulin gamma Fc receptor II-b
K03084 SHIP1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
K15909 SHIP2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K08091 GAB2; GRB2-associated-binding protein 2
K07362 LAT; linker for activation of T cells
K23484 DNM2; dynamin 2 [EC:3.6.5.5]
K12562 AMPH; amphiphysin
K12562 AMPH; amphiphysin
K12559 MYO10; myosin X
     04670 Leukocyte transendothelial migration [PATH:pon04670]
     04672 Intestinal immune network for IgA production [PATH:pon04672]
     04062 Chemokine signaling pathway [PATH:pon04062]
 
   09152 Endocrine system
 
   09153 Circulatory system
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
 
   09149 Aging
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
   09161 Cancer: overview
     05200 Pathways in cancer [PATH:pon05200]
     05202 Transcriptional misregulation in cancer [PATH:pon05202]
     05206 MicroRNAs in cancer [PATH:pon05206]
       100171828 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
       100449905 CDKN1B; cyclin-dependent kinase inhibitor 1B
       100440197 TIMP3; metalloproteinase inhibitor 3
       100462513 KRAS; GTPase KRas isoform X1
       100454924 CDK6; cyclin-dependent kinase 6
       100460228 CDC25A; M-phase inducer phosphatase 1 isoform X3
       100434256 CDC25B; M-phase inducer phosphatase 2 isoform X1
       100451443 CDC25C; M-phase inducer phosphatase 3 isoform X1
       100436170 HMGA2; high mobility group protein HMGI-C isoform X2
       100171625 CCND1; G1/S-specific cyclin-D1
       100457978 CCND2; G1/S-specific cyclin-D2
       100438282 CCNE2; G1/S-specific cyclin-E2 isoform X1
       100461587 CCNE1; G1/S-specific cyclin-E1 isoform X1
       100452410 CRK; adapter molecule crk isoform X1
       100443298 CRKL; crk-like protein
       100458256 HDAC5; histone deacetylase 5 isoform X1
       100440788 HDAC4; histone deacetylase 4 isoform X1
       100432353 FOXP1; forkhead box protein P1 isoform X7
       100461844 PIM1; serine/threonine-protein kinase pim-1
       100137030 MET; hepatocyte growth factor receptor precursor
       100459471 DNMT3A; DNA (cytosine-5)-methyltransferase 3A isoform X1
       100459992 DNMT3B; DNA (cytosine-5)-methyltransferase 3B isoform X1
       100436188 MCL1; induced myeloid leukemia cell differentiation protein Mcl-1 isoform X1
       100442963 bcl-2-like protein 2 isoform X3
       100459280 EGFR; epidermal growth factor receptor isoform X2
       100448769 VEGFA; vascular endothelial growth factor A isoform X1
       100171534 ZEB1; zinc finger E-box-binding homeobox 1
       100461291 TGFB2; transforming growth factor beta-2 isoform X1
       100458178 EZR; ezrin isoform X1
       100173014 PDCD4; programmed cell death protein 4
       100455260 EP300; histone acetyltransferase p300 isoform X2
       100445634 CREBBP; LOW QUALITY PROTEIN: CREB-binding protein
       100172445 TPM1; tropomyosin alpha-1 chain
       100173576 SPRY2; protein sprouty homolog 2
       100938429 BCL2; apoptosis regulator Bcl-2 isoform X1
       100444556 SERPINB5; serpin B5
       100448596 ST14; suppressor of tumorigenicity 14 protein
       100172192 CYP1B1; cytochrome P450 1B1
       100456786 MTOR; serine/threonine-protein kinase mTOR
       100434731 RPTOR; regulatory-associated protein of mTOR isoform X1
       100457433 1
       100450307 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
       100174431 ERBB3; receptor tyrosine-protein kinase erbB-3 precursor
       100453216 ABL1; tyrosine-protein kinase ABL1 isoform X1
       100444448 TP63; tumor protein 63 isoform X1
       100171900 ZEB2; zinc finger E-box-binding homeobox 2
       100439960 FSCN1; LOW QUALITY PROTEIN: fascin
       103888520 RASSF1; ras association domain-containing protein 1 isoform X3
       100174239 HOXD10; homeobox protein Hox-D10
       100445736 DDIT4; DNA damage-inducible transcript 4 protein
       100454976 BMF; bcl-2-modifying factor isoform X3
       100457556 PAK4; serine/threonine-protein kinase PAK 4 isoform X1
       100455867 MMP9; LOW QUALITY PROTEIN: matrix metalloproteinase-9
       100459572 SLC7A1; high affinity cationic amino acid transporter 1
       100173395 CCNG1; cyclin-G1
       100173339 HMOX1; heme oxygenase 1
       100435715 STMN1; stathmin
       100171541 STAT3; signal transducer and activator of transcription 3
       100456735 MYC; myc proto-oncogene protein
       100435491 CASP3; caspase-3
       100459427 HRAS; GTPase HRas
       100174317 NRAS; GTPase NRas precursor
       100436978 DNMT1; DNA (cytosine-5)-methyltransferase 1 isoform X1
       100431482 APC; adenomatous polyposis coli protein isoform X2
       100435472 APC2; adenomatous polyposis coli protein 2 isoform X1
       100442255 IRS1; insulin receptor substrate 1
       100174298 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       100173589 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
       100437617 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100451029 MAPK7; mitogen-activated protein kinase 7 isoform X1
       100432846 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100453779 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       103889133 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       100173769 HNRNPK; heterogeneous nuclear ribonucleoprotein K
       100431403 RECK; reversion-inducing cysteine-rich protein with Kazal motifs isoform X1
       100448297 E2F3; transcription factor E2F3 isoform X3
       100452233 IRS2; insulin receptor substrate 2
       100449179 NOTCH1; neurogenic locus notch homolog protein 1
       100447628 NOTCH2; neurogenic locus notch homolog protein 2 isoform X1
       100454773 NOTCH3; neurogenic locus notch homolog protein 3
       100436768 NOTCH4; neurogenic locus notch homolog protein 4
       100173052 BMI1; polycomb complex protein BMI-1
       100447086 MMP16; matrix metalloproteinase-16 isoform X1
       100451505 ATM; serine-protein kinase ATM isoform X1
       100445635 SOCS1; suppressor of cytokine signaling 1
       100172786 CD44; CD44 antigen precursor
       100462160 DICER1; endoribonuclease Dicer isoform X1
       100457942 FZD3; frizzled-3
       100453984 ITGA5; integrin alpha-5
       100453730 RDX; radixin isoform X2
       100171605 RHOA; transforming protein RhoA precursor
       100171578 PLAU; urokinase-type plasminogen activator precursor
       100460189 bcl-2 homologous antagonist/killer
       100432001 BAK1; bcl-2 homologous antagonist/killer isoform X1
       100444744 ZFPM2; zinc finger protein ZFPM2 isoform X1
       100445345 ITGB3; integrin beta-3
       100454750 UBE2I; SUMO-conjugating enzyme UBC9
       100449029 SOX4; transcription factor SOX-4
       100451868 TNC; tenascin isoform X4
       100443502 TNXB; LOW QUALITY PROTEIN: tenascin-X
       100452638 TNR; tenascin-R isoform X1
       100453010 TNN; tenascin-N isoform X1
       100452463 ABCB1; multidrug resistance protein 1
       100431822 ABCC1; multidrug resistance-associated protein 1
       100439533 BRCA1; breast cancer type 1 susceptibility protein isoform X5
       100453682 CDKN1A; cyclin-dependent kinase inhibitor 1
       100448360 EFNA1; ephrin-A1
       100448970 EFNA3; ephrin-A3 isoform X1
       100449916 EFNA4; ephrin-A4 isoform X2
       100451193 EFNA5; ephrin-A5
       112130075 EFNA2; ephrin-A2
       100453386 THBS1; thrombospondin-1
       100451737 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1 isoform X1
       100446303 TRIM71; E3 ubiquitin-protein ligase TRIM71
       100461595 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       100440586 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X3
       100436566 PTGS2; prostaglandin G/H synthase 2
       100169740 MAPK1; mitogen-activated protein kinase 1 isoform X1
       100431824 MAPK3; LOW QUALITY PROTEIN: mitogen-activated protein kinase 3
       100434355 PRKCA; protein kinase C alpha type isoform X1
       100439900 PRKCB; protein kinase C beta type isoform X2
       100451563 PRKCG; protein kinase C gamma type
       100173972 GRB2; growth factor receptor-bound protein 2
       100433126 FGFR3; LOW QUALITY PROTEIN: fibroblast growth factor receptor 3
       100173967 RPS6KA5; ribosomal protein S6 kinase alpha-5
       100435218 TP53; cellular tumor antigen p53
       100171532 MDM2; E3 ubiquitin-protein ligase Mdm2
       100461293 MDM4; protein Mdm4
       100431735 PDGFRA; platelet-derived growth factor receptor alpha
       100450941 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2
       100457650 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       100173732 RAF1; RAF proto-oncogene serine/threonine-protein kinase
       100446021 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       100450988 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       100434331 SOS2; son of sevenless homolog 2 isoform X1
       100458733 SOS1; son of sevenless homolog 1 isoform X1
       100173225 SHC1; SHC-transforming protein 1
       100440212 PDGFA; platelet-derived growth factor subunit A isoform X1
       100431574 SHC4; SHC-transforming protein 4
       100460243 PDGFB; platelet-derived growth factor subunit B
       100460001 PDGFRB; platelet-derived growth factor receptor beta isoform X1
       100461015 cyclin-dependent kinase inhibitor 2A
       100435851 E2F1; transcription factor E2F1
       100458002 E2F2; transcription factor E2F2 isoform X1
       100443209 BCL2L11; bcl-2-like protein 11 isoform X1
       100445187 MARCKS; myristoylated alanine-rich C-kinase substrate
       100441517 BMPR2; bone morphogenetic protein receptor type-2
       100172663 HDAC1; histone deacetylase 1
       100294534 HDAC2; histone deacetylase 2
       100447447 EZH2; histone-lysine N-methyltransferase EZH2 isoform X1
       100431592 GLS; glutaminase kidney isoform, mitochondrial isoform X1
       100453856 GLS2; glutaminase liver isoform, mitochondrial isoform X2
       100443901 SIRT1; NAD-dependent protein deacetylase sirtuin-1 isoform X1
       100431449 WNT3; proto-oncogene Wnt-3
       100448240 WNT3A; protein Wnt-3a isoform X1
       100445606 CDCA5; sororin
       100460820 KIF23; kinesin-like protein KIF23 isoform X1
       100432582 ROCK1; rho-associated protein kinase 1
       100440778 PRKCE; protein kinase C epsilon type
       100454606 SLC45A3; solute carrier family 45 member 3
       100936414 VIM; vimentin
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16866 TIMP3; metalloproteinase inhibitor 3
K07827 KRAS; GTPase KRas
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K09283 HMGA2; high mobility group AT-hook protein 2
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K23582 FOXP1; forkhead box protein P1
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K02163 BCLW; apoptosis regulator BCL-W
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K09299 ZEB1; zinc finger homeobox protein 1
K13376 TGFB2; transforming growth factor beta-2
K08007 VIL2; villin 2 (ezrin)
K16865 PDCD4; programmed cell death protein 4
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K10373 TPM1; tropomyosin 1
K17383 SPRY2; protein sprouty homolog 2
K02161 BCL2; apoptosis regulator Bcl-2
K10139 SERPINB5; serpin B5
K08670 ST14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07436 CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.15.16]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K10149 TP63; tumor protein p63
K23560 ZEB2; zinc finger homeobox protein 2
K23551 FSCN1; fascin 1
K09850 RASSF1; Ras association domain-containing protein 1
K09295 HOXD10; homrobox protein Hox-D10
K08270 DDIT4; DNA-damage-inducible transcript 4
K17460 BMF; Bcl-2-modifying factor
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K13863 SLC7A1; solute carrier family 7 (cationic amino acid transporter), member 1
K10145 CCNG1; cyclin G1
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K04381 STMN1; stathmin
K04692 STAT3; signal transducer and activator of transcription 3
K04377 MYC; Myc proto-oncogene protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
K17461 RECK; reversion-inducing-cysteine-rich protein with kazal motifs
K06620 E2F3; transcription factor E2F3
K07187 IRS2; insulin receptor substrate 2
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K11459 PCGF4; polycomb group RING finger protein 4
K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04694 SOCS1; suppressor of cytokine signaling 1
K06256 CD44; CD44 antigen
K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
K02329 FZD3; frizzled 3
K06484 ITGA5; integrin alpha 5
K05762 RDX; radixin
K04513 RHOA; Ras homolog gene family, member A
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K14021 BAK; Bcl-2 homologous antagonist/killer
K14021 BAK; Bcl-2 homologous antagonist/killer
K17442 ZFPM2; zinc finger protein ZFPM2
K06493 ITGB3; integrin beta 3
K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
K23581 SOX4; transcription factor SOX4 (SOX group C)
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K16857 THBS1; thrombospondin 1
K17391 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04364 GRB2; growth factor receptor-bound protein 2
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K06279 SHC1; SHC-transforming protein 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17449 SHC4; SHC-transforming protein 4
K17386 PDGFB; platelet-derived growth factor subunit B
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K16341 BCL2L11; Bcl-2-like protein 11
K12561 MARCKS; myristoylated alanine-rich C-kinase substrate
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K01425 glsA; glutaminase [EC:3.5.1.2]
K01425 glsA; glutaminase [EC:3.5.1.2]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K17390 CDCA5; sororin
K17387 KIF23; kinesin family member 23
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K15379 SLC45A3; solute carrier family 45, member 3
K07606 VIM; vimentin
     05205 Proteoglycans in cancer [PATH:pon05205]
     05204 Chemical carcinogenesis [PATH:pon05204]
     05203 Viral carcinogenesis [PATH:pon05203]
     05230 Central carbon metabolism in cancer [PATH:pon05230]
     05231 Choline metabolism in cancer [PATH:pon05231]
     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:pon05235]
 
   09162 Cancer: specific types
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: March 2, 2021