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KO |
 09100 Metabolism
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09140 Cellular Processes
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 09150 Organismal Systems
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09151 Immune system
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04640 Hematopoietic cell lineage [PATH:pon04640]
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04610 Complement and coagulation cascades [PATH:pon04610]
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04611 Platelet activation [PATH:pon04611]
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04613 Neutrophil extracellular trap formation [PATH:pon04613]
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04620 Toll-like receptor signaling pathway [PATH:pon04620]
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 04624 Toll and Imd signaling pathway
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04621 NOD-like receptor signaling pathway [PATH:pon04621]
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04622 RIG-I-like receptor signaling pathway [PATH:pon04622]
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04623 Cytosolic DNA-sensing pathway [PATH:pon04623]
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04625 C-type lectin receptor signaling pathway [PATH:pon04625]
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04650 Natural killer cell mediated cytotoxicity [PATH:pon04650]
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04612 Antigen processing and presentation [PATH:pon04612]
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04660 T cell receptor signaling pathway [PATH:pon04660]
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04658 Th1 and Th2 cell differentiation [PATH:pon04658]
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04659 Th17 cell differentiation [PATH:pon04659]
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04657 IL-17 signaling pathway [PATH:pon04657]
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04662 B cell receptor signaling pathway [PATH:pon04662]
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04664 Fc epsilon RI signaling pathway [PATH:pon04664]
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04666 Fc gamma R-mediated phagocytosis [PATH:pon04666]
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100939231 uncharacterized protein LOC100939231
100939054 immunoglobulin alpha-2 heavy chain-like
100939294 uncharacterized protein LOC100939294
100431520 immunoglobulin delta heavy chain-like
100431914 high affinity immunoglobulin gamma Fc receptor I isoform X2
100455333 FCGR2A; low affinity immunoglobulin gamma Fc region receptor II-a isoform X1
100453994 low affinity immunoglobulin gamma Fc region receptor III-A isoform X1
100446144 PTPRC; receptor-type tyrosine-protein phosphatase C isoform X1
100455620 HCK; tyrosine-protein kinase HCK
100447326 LYN; tyrosine-protein kinase Lyn isoform X1
100438875 SYK; tyrosine-protein kinase SYK isoform X1
100432846 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
100453779 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
103889133 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100174298 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
100173589 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
100437617 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100454279 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
100448114 AKT3; RAC-gamma serine/threonine-protein kinase
100442100 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
100462008 LOW QUALITY PROTEIN: ribosomal protein S6 kinase beta-1
100459428 RPS6KB2; ribosomal protein S6 kinase beta-2
100456988 RPS6KB1; LOW QUALITY PROTEIN: ribosomal protein S6 kinase beta-1
100450941 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2
100457650 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
100452668 PRKCD; protein kinase C delta type isoform X1
100440778 PRKCE; protein kinase C epsilon type
100173732 RAF1; RAF proto-oncogene serine/threonine-protein kinase
100446021 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
100169740 MAPK1; mitogen-activated protein kinase 1 isoform X1
100431824 MAPK3; LOW QUALITY PROTEIN: mitogen-activated protein kinase 3
100454614 PLA2G4E; cytosolic phospholipase A2 epsilon
100173125 PLA2G4A; cytosolic phospholipase A2
100447631 PLA2G4B; cytosolic phospholipase A2 beta
100434495 PLA2G4C; cytosolic phospholipase A2 gamma isoform X3
100454977 PLA2G4D; cytosolic phospholipase A2 delta
100448616 PLA2G4F; cytosolic phospholipase A2 zeta
100445065 PLA2G6; 85/88 kDa calcium-independent phospholipase A2 isoform X2
100445187 MARCKS; myristoylated alanine-rich C-kinase substrate
100434835 MARCKSL1; MARCKS-related protein
100439813 PLD1; phospholipase D1 isoform X1
100457163 PLD2; phospholipase D2
100442989 PLPP2; phospholipid phosphatase 2 isoform X1
100448168 PLPP1; phospholipid phosphatase 1 isoform X1
100455097 PLPP3; phospholipid phosphatase 3
100433232 SPHK1; sphingosine kinase 1 isoform X1
100172513 SPHK2; sphingosine kinase 2
100434355 PRKCA; protein kinase C alpha type isoform X1
100439900 PRKCB; protein kinase C beta type isoform X2
100451563 PRKCG; protein kinase C gamma type
100442050 NCF1; neutrophil cytosol factor 1
100172865 GSN; gelsolin
100441440 SCIN; adseverin isoform X1
100442703 VAV3; guanine nucleotide exchange factor VAV3
100171723 VAV2; guanine nucleotide exchange factor VAV2
100447155 VAV1; proto-oncogene vav isoform X1
100438199 CDC42; cell division control protein 42 homolog
100452449 WAS; LOW QUALITY PROTEIN: wiskott-Aldrich syndrome protein
100462324 VASP; vasodilator-stimulated phosphoprotein isoform X1
100173969 ACTR2; actin-related protein 2
100454564 ACTR3B; LOW QUALITY PROTEIN: actin-related protein 3B
100173023 ACTR3; actin-related protein 3
100461245 ARPC1A; actin-related protein 2/3 complex subunit 1A
100458060 ARPC1B; actin-related protein 2/3 complex subunit 1B
100173646 ARPC2; actin-related protein 2/3 complex subunit 2
100460433 ARPC3; actin-related protein 2/3 complex subunit 3
100936009 ARPC4; actin-related protein 2/3 complex subunit 4 isoform X1
100173958 ARPC5L; actin-related protein 2/3 complex subunit 5-like protein
100174767 ARPC5; actin-related protein 2/3 complex subunit 5
100443271 RAC1; ras-related C3 botulinum toxin substrate 1
100431483 RAC2; ras-related C3 botulinum toxin substrate 2
100174148 WASF1; wiskott-Aldrich syndrome protein family member 1
100437132 LOW QUALITY PROTEIN: wiskott-Aldrich syndrome protein family member 2-like
100447501 WASF2; wiskott-Aldrich syndrome protein family member 2
100445243 WASF3; wiskott-Aldrich syndrome protein family member 3 isoform X1
100449316 PAK1; serine/threonine-protein kinase PAK 1 isoform X1
100432626 LIMK1; LIM domain kinase 1
100460494 LIMK2; LIM domain kinase 2 isoform X1
100454363 CFL2; cofilin-2 isoform X1
103891788 CFL1; cofilin-1 isoform X1
100456775 PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X3
100432274 PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta
100435603 PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1
100443776 putative PIP5K1A and PSMD4-like protein
100444466 phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1
100432444 ARF6; ADP-ribosylation factor 6
100452410 CRK; adapter molecule crk isoform X1
100443298 CRKL; crk-like protein
100462022 DOCK1; dedicator of cytokinesis protein 1 isoform X1
100460279 ASAP1; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1
100458725 ASAP3; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X1
100440164 ASAP2; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform X1
100453137 FCGR2B; low affinity immunoglobulin gamma Fc region receptor II-b isoform X3
100446045 INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
100450015 INPPL1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1
100457376 GAB2; GRB2-associated-binding protein 2
100453027 LAT; linker for activation of T-cells family member 1 isoform X2
100442734 DNM2; dynamin-2 isoform X1
100446471 AMPH; amphiphysin
103889932 BIN1; myc box-dependent-interacting protein 1 isoform X3
100432603 MYO10; unconventional myosin-X isoform X1
|
K06856 IGH; immunoglobulin heavy chain
K06856 IGH; immunoglobulin heavy chain
K06856 IGH; immunoglobulin heavy chain
K06856 IGH; immunoglobulin heavy chain
K06498 FCGR1A; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A; low affinity immunoglobulin gamma Fc receptor II-a
K06463 FCGR3; low affinity immunoglobulin gamma Fc receptor III
K06478 PTPRC; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
K12561 MARCKS; myristoylated alanine-rich C-kinase substrate
K13536 MARCKSL1; MARCKS-related protein
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K08011 NCF1; neutrophil cytosolic factor 1
K05768 GSN; gelsolin
K05768 GSN; gelsolin
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K04393 CDC42; cell division control protein 42
K05747 WAS; Wiskott-Aldrich syndrome protein
K06274 VASP; vasodilator-stimulated phosphoprotein
K17260 ACTR2; actin-related protein 2
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K05753 WASF1; WAS protein family, member 1
K05748 WASF2; WAS protein family, member 2
K05748 WASF2; WAS protein family, member 2
K06083 WASF3; WAS protein family, member 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05765 CFL; cofilin
K05765 CFL; cofilin
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K07941 ARF6; ADP-ribosylation factor 6
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
K12560 FCGR2B; low affinity immunoglobulin gamma Fc receptor II-b
K03084 SHIP1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
K15909 SHIP2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K08091 GAB2; GRB2-associated-binding protein 2
K07362 LAT; linker for activation of T cells
K23484 DNM2; dynamin 2 [EC:3.6.5.5]
K12562 AMPH; amphiphysin
K12562 AMPH; amphiphysin
K12559 MYO10; myosin X
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04670 Leukocyte transendothelial migration [PATH:pon04670]
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04672 Intestinal immune network for IgA production [PATH:pon04672]
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04062 Chemokine signaling pathway [PATH:pon04062]
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09152 Endocrine system
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09153 Circulatory system
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09154 Digestive system
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09155 Excretory system
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09156 Nervous system
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09157 Sensory system
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09158 Development and regeneration
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09149 Aging
|
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09159 Environmental adaptation
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09160 Human Diseases
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09161 Cancer: overview
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05200 Pathways in cancer [PATH:pon05200]
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05202 Transcriptional misregulation in cancer [PATH:pon05202]
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05206 MicroRNAs in cancer [PATH:pon05206]
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100171828 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
100449905 CDKN1B; cyclin-dependent kinase inhibitor 1B
100440197 TIMP3; metalloproteinase inhibitor 3
100462513 KRAS; GTPase KRas isoform X1
100454924 CDK6; cyclin-dependent kinase 6
100460228 CDC25A; M-phase inducer phosphatase 1 isoform X3
100434256 CDC25B; M-phase inducer phosphatase 2 isoform X1
100451443 CDC25C; M-phase inducer phosphatase 3 isoform X1
100436170 HMGA2; high mobility group protein HMGI-C isoform X2
100171625 CCND1; G1/S-specific cyclin-D1
100457978 CCND2; G1/S-specific cyclin-D2
100438282 CCNE2; G1/S-specific cyclin-E2 isoform X1
100461587 CCNE1; G1/S-specific cyclin-E1 isoform X1
100452410 CRK; adapter molecule crk isoform X1
100443298 CRKL; crk-like protein
100458256 HDAC5; histone deacetylase 5 isoform X1
100440788 HDAC4; histone deacetylase 4 isoform X1
100432353 FOXP1; forkhead box protein P1 isoform X7
100461844 PIM1; serine/threonine-protein kinase pim-1
100137030 MET; hepatocyte growth factor receptor precursor
100459471 DNMT3A; DNA (cytosine-5)-methyltransferase 3A isoform X1
100459992 DNMT3B; DNA (cytosine-5)-methyltransferase 3B isoform X1
100436188 MCL1; induced myeloid leukemia cell differentiation protein Mcl-1 isoform X1
100442963 bcl-2-like protein 2 isoform X3
100459280 EGFR; epidermal growth factor receptor isoform X2
100448769 VEGFA; vascular endothelial growth factor A isoform X1
100171534 ZEB1; zinc finger E-box-binding homeobox 1
100461291 TGFB2; transforming growth factor beta-2 isoform X1
100458178 EZR; ezrin isoform X1
100173014 PDCD4; programmed cell death protein 4
100455260 EP300; histone acetyltransferase p300 isoform X2
100445634 CREBBP; LOW QUALITY PROTEIN: CREB-binding protein
100172445 TPM1; tropomyosin alpha-1 chain
100173576 SPRY2; protein sprouty homolog 2
100938429 BCL2; apoptosis regulator Bcl-2 isoform X1
100444556 SERPINB5; serpin B5
100448596 ST14; suppressor of tumorigenicity 14 protein
100172192 CYP1B1; cytochrome P450 1B1
100456786 MTOR; serine/threonine-protein kinase mTOR
100434731 RPTOR; regulatory-associated protein of mTOR isoform X1
100457433 1
100450307 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
100174431 ERBB3; receptor tyrosine-protein kinase erbB-3 precursor
100453216 ABL1; tyrosine-protein kinase ABL1 isoform X1
100444448 TP63; tumor protein 63 isoform X1
100171900 ZEB2; zinc finger E-box-binding homeobox 2
100439960 FSCN1; LOW QUALITY PROTEIN: fascin
103888520 RASSF1; ras association domain-containing protein 1 isoform X3
100174239 HOXD10; homeobox protein Hox-D10
100445736 DDIT4; DNA damage-inducible transcript 4 protein
100454976 BMF; bcl-2-modifying factor isoform X3
100457556 PAK4; serine/threonine-protein kinase PAK 4 isoform X1
100455867 MMP9; LOW QUALITY PROTEIN: matrix metalloproteinase-9
100459572 SLC7A1; high affinity cationic amino acid transporter 1
100173395 CCNG1; cyclin-G1
100173339 HMOX1; heme oxygenase 1
100435715 STMN1; stathmin
100171541 STAT3; signal transducer and activator of transcription 3
100456735 MYC; myc proto-oncogene protein
100435491 CASP3; caspase-3
100459427 HRAS; GTPase HRas
100174317 NRAS; GTPase NRas precursor
100436978 DNMT1; DNA (cytosine-5)-methyltransferase 1 isoform X1
100431482 APC; adenomatous polyposis coli protein isoform X2
100435472 APC2; adenomatous polyposis coli protein 2 isoform X1
100442255 IRS1; insulin receptor substrate 1
100174298 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
100173589 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
100437617 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100451029 MAPK7; mitogen-activated protein kinase 7 isoform X1
100432846 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
100453779 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
103889133 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100173769 HNRNPK; heterogeneous nuclear ribonucleoprotein K
100431403 RECK; reversion-inducing cysteine-rich protein with Kazal motifs isoform X1
100448297 E2F3; transcription factor E2F3 isoform X3
100452233 IRS2; insulin receptor substrate 2
100449179 NOTCH1; neurogenic locus notch homolog protein 1
100447628 NOTCH2; neurogenic locus notch homolog protein 2 isoform X1
100454773 NOTCH3; neurogenic locus notch homolog protein 3
100436768 NOTCH4; neurogenic locus notch homolog protein 4
100173052 BMI1; polycomb complex protein BMI-1
100447086 MMP16; matrix metalloproteinase-16 isoform X1
100451505 ATM; serine-protein kinase ATM isoform X1
100445635 SOCS1; suppressor of cytokine signaling 1
100172786 CD44; CD44 antigen precursor
100462160 DICER1; endoribonuclease Dicer isoform X1
100457942 FZD3; frizzled-3
100453984 ITGA5; integrin alpha-5
100453730 RDX; radixin isoform X2
100171605 RHOA; transforming protein RhoA precursor
100171578 PLAU; urokinase-type plasminogen activator precursor
100460189 bcl-2 homologous antagonist/killer
100432001 BAK1; bcl-2 homologous antagonist/killer isoform X1
100444744 ZFPM2; zinc finger protein ZFPM2 isoform X1
100445345 ITGB3; integrin beta-3
100454750 UBE2I; SUMO-conjugating enzyme UBC9
100449029 SOX4; transcription factor SOX-4
100451868 TNC; tenascin isoform X4
100443502 TNXB; LOW QUALITY PROTEIN: tenascin-X
100452638 TNR; tenascin-R isoform X1
100453010 TNN; tenascin-N isoform X1
100452463 ABCB1; multidrug resistance protein 1
100431822 ABCC1; multidrug resistance-associated protein 1
100439533 BRCA1; breast cancer type 1 susceptibility protein isoform X5
100453682 CDKN1A; cyclin-dependent kinase inhibitor 1
100448360 EFNA1; ephrin-A1
100448970 EFNA3; ephrin-A3 isoform X1
100449916 EFNA4; ephrin-A4 isoform X2
100451193 EFNA5; ephrin-A5
112130075 EFNA2; ephrin-A2
100453386 THBS1; thrombospondin-1
100451737 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1 isoform X1
100446303 TRIM71; E3 ubiquitin-protein ligase TRIM71
100461595 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
100440586 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X3
100436566 PTGS2; prostaglandin G/H synthase 2
100169740 MAPK1; mitogen-activated protein kinase 1 isoform X1
100431824 MAPK3; LOW QUALITY PROTEIN: mitogen-activated protein kinase 3
100434355 PRKCA; protein kinase C alpha type isoform X1
100439900 PRKCB; protein kinase C beta type isoform X2
100451563 PRKCG; protein kinase C gamma type
100173972 GRB2; growth factor receptor-bound protein 2
100433126 FGFR3; LOW QUALITY PROTEIN: fibroblast growth factor receptor 3
100173967 RPS6KA5; ribosomal protein S6 kinase alpha-5
100435218 TP53; cellular tumor antigen p53
100171532 MDM2; E3 ubiquitin-protein ligase Mdm2
100461293 MDM4; protein Mdm4
100431735 PDGFRA; platelet-derived growth factor receptor alpha
100450941 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2
100457650 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
100173732 RAF1; RAF proto-oncogene serine/threonine-protein kinase
100446021 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
100450988 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
100434331 SOS2; son of sevenless homolog 2 isoform X1
100458733 SOS1; son of sevenless homolog 1 isoform X1
100173225 SHC1; SHC-transforming protein 1
100440212 PDGFA; platelet-derived growth factor subunit A isoform X1
100431574 SHC4; SHC-transforming protein 4
100460243 PDGFB; platelet-derived growth factor subunit B
100460001 PDGFRB; platelet-derived growth factor receptor beta isoform X1
100461015 cyclin-dependent kinase inhibitor 2A
100435851 E2F1; transcription factor E2F1
100458002 E2F2; transcription factor E2F2 isoform X1
100443209 BCL2L11; bcl-2-like protein 11 isoform X1
100445187 MARCKS; myristoylated alanine-rich C-kinase substrate
100441517 BMPR2; bone morphogenetic protein receptor type-2
100172663 HDAC1; histone deacetylase 1
100294534 HDAC2; histone deacetylase 2
100447447 EZH2; histone-lysine N-methyltransferase EZH2 isoform X1
100431592 GLS; glutaminase kidney isoform, mitochondrial isoform X1
100453856 GLS2; glutaminase liver isoform, mitochondrial isoform X2
100443901 SIRT1; NAD-dependent protein deacetylase sirtuin-1 isoform X1
100431449 WNT3; proto-oncogene Wnt-3
100448240 WNT3A; protein Wnt-3a isoform X1
100445606 CDCA5; sororin
100460820 KIF23; kinesin-like protein KIF23 isoform X1
100432582 ROCK1; rho-associated protein kinase 1
100440778 PRKCE; protein kinase C epsilon type
100454606 SLC45A3; solute carrier family 45 member 3
100936414 VIM; vimentin
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K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16866 TIMP3; metalloproteinase inhibitor 3
K07827 KRAS; GTPase KRas
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K09283 HMGA2; high mobility group AT-hook protein 2
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K23582 FOXP1; forkhead box protein P1
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K02163 BCLW; apoptosis regulator BCL-W
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K09299 ZEB1; zinc finger homeobox protein 1
K13376 TGFB2; transforming growth factor beta-2
K08007 VIL2; villin 2 (ezrin)
K16865 PDCD4; programmed cell death protein 4
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K10373 TPM1; tropomyosin 1
K17383 SPRY2; protein sprouty homolog 2
K02161 BCL2; apoptosis regulator Bcl-2
K10139 SERPINB5; serpin B5
K08670 ST14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07436 CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.15.16]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K10149 TP63; tumor protein p63
K23560 ZEB2; zinc finger homeobox protein 2
K23551 FSCN1; fascin 1
K09850 RASSF1; Ras association domain-containing protein 1
K09295 HOXD10; homrobox protein Hox-D10
K08270 DDIT4; DNA-damage-inducible transcript 4
K17460 BMF; Bcl-2-modifying factor
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K13863 SLC7A1; solute carrier family 7 (cationic amino acid transporter), member 1
K10145 CCNG1; cyclin G1
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K04381 STMN1; stathmin
K04692 STAT3; signal transducer and activator of transcription 3
K04377 MYC; Myc proto-oncogene protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
K17461 RECK; reversion-inducing-cysteine-rich protein with kazal motifs
K06620 E2F3; transcription factor E2F3
K07187 IRS2; insulin receptor substrate 2
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K11459 PCGF4; polycomb group RING finger protein 4
K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04694 SOCS1; suppressor of cytokine signaling 1
K06256 CD44; CD44 antigen
K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
K02329 FZD3; frizzled 3
K06484 ITGA5; integrin alpha 5
K05762 RDX; radixin
K04513 RHOA; Ras homolog gene family, member A
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K14021 BAK; Bcl-2 homologous antagonist/killer
K14021 BAK; Bcl-2 homologous antagonist/killer
K17442 ZFPM2; zinc finger protein ZFPM2
K06493 ITGB3; integrin beta 3
K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
K23581 SOX4; transcription factor SOX4 (SOX group C)
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K16857 THBS1; thrombospondin 1
K17391 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04364 GRB2; growth factor receptor-bound protein 2
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K06279 SHC1; SHC-transforming protein 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17449 SHC4; SHC-transforming protein 4
K17386 PDGFB; platelet-derived growth factor subunit B
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K16341 BCL2L11; Bcl-2-like protein 11
K12561 MARCKS; myristoylated alanine-rich C-kinase substrate
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K01425 glsA; glutaminase [EC:3.5.1.2]
K01425 glsA; glutaminase [EC:3.5.1.2]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K17390 CDCA5; sororin
K17387 KIF23; kinesin family member 23
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K15379 SLC45A3; solute carrier family 45, member 3
K07606 VIM; vimentin
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05205 Proteoglycans in cancer [PATH:pon05205]
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05204 Chemical carcinogenesis [PATH:pon05204]
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05203 Viral carcinogenesis [PATH:pon05203]
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05230 Central carbon metabolism in cancer [PATH:pon05230]
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05231 Choline metabolism in cancer [PATH:pon05231]
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05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:pon05235]
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09162 Cancer: specific types
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09172 Infectious disease: viral
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09171 Infectious disease: bacterial
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09174 Infectious disease: parasitic
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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09167 Endocrine and metabolic disease
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Pongo abelii (Sumatran orangutan)