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KO |
 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
|
 02020 Two-component system
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04010 MAPK signaling pathway [PATH:pon04010]
|
04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
|
04011 MAPK signaling pathway - yeast
|
04012 ErbB signaling pathway [PATH:pon04012]
|
100455021 EGF; pro-epidermal growth factor isoform X1
100172994 TGFA; protransforming growth factor alpha precursor
100443606 AREG; amphiregulin
100459280 EGFR; epidermal growth factor receptor isoform X2
100450307 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
100450941 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2
100457650 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
100433531 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1
100172212 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha
100462386 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1
100436747 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1
100434355 PRKCA; protein kinase C alpha type isoform X1
100439900 PRKCB; protein kinase C beta type isoform X2
100451563 PRKCG; protein kinase C gamma type
100462634 CBL; E3 ubiquitin-protein ligase CBL
100452289 CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1
100461695 STAT5A; signal transducer and activator of transcription 5A isoform X1
100462537 STAT5B; signal transducer and activator of transcription 5B isoform X1
100436498 SRC; proto-oncogene tyrosine-protein kinase Src isoform X1
100447959 PTK2; focal adhesion kinase 1 isoform X1
100452410 CRK; adapter molecule crk isoform X1
100443298 CRKL; crk-like protein
100453216 ABL1; tyrosine-protein kinase ABL1 isoform X1
100437449 ABL2; Abelson tyrosine-protein kinase 2 isoform X2
100171550 NCK1; cytoplasmic protein NCK1
100452789 NCK2; cytoplasmic protein NCK2 isoform X1
100449316 PAK1; serine/threonine-protein kinase PAK 1 isoform X1
100439815 PAK2; serine/threonine-protein kinase PAK 2
100294571 PAK3; serine/threonine-protein kinase PAK 3
100457556 PAK4; serine/threonine-protein kinase PAK 4 isoform X1
100174593 PAK7; serine/threonine-protein kinase PAK 7
100172971 PAK6; serine/threonine-protein kinase PAK 6
100439299 MAP2K4; dual specificity mitogen-activated protein kinase kinase 4
100431600 MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X2
100174482 MAPK10; mitogen-activated protein kinase 10
100459133 MAPK9; mitogen-activated protein kinase 9 isoform X1
100437424 MAPK8; mitogen-activated protein kinase 8 isoform X1
100450292 JUN; transcription factor AP-1
100432611 ELK1; ETS domain-containing protein Elk-1
100445807 BTC; probetacellulin isoform X1
100437870 HBEGF; proheparin-binding EGF-like growth factor
100443243 EREG; proepiregulin
100174431 ERBB3; receptor tyrosine-protein kinase erbB-3 precursor
100171905 NRG1; pro-neuregulin-1, membrane-bound isoform
100432995 NRG2; pro-neuregulin-2, membrane-bound isoform isoform X1
100938677 ERBB4; receptor tyrosine-protein kinase erbB-4 isoform X1
100173225 SHC1; SHC-transforming protein 1
100445042 SHC2; SHC-transforming protein 2
100462011 SHC3; SHC-transforming protein 3
100431574 SHC4; SHC-transforming protein 4
100173972 GRB2; growth factor receptor-bound protein 2
100434331 SOS2; son of sevenless homolog 2 isoform X1
100458733 SOS1; son of sevenless homolog 1 isoform X1
100459427 HRAS; GTPase HRas
100462513 KRAS; GTPase KRas isoform X1
100174317 NRAS; GTPase NRas precursor
100431871 ARAF; serine/threonine-protein kinase A-Raf isoform X4
100442288 BRAF; serine/threonine-protein kinase B-raf isoform X1
100173732 RAF1; RAF proto-oncogene serine/threonine-protein kinase
100446021 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
100450988 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
100169740 MAPK1; mitogen-activated protein kinase 1 isoform X1
100431824 MAPK3; LOW QUALITY PROTEIN: mitogen-activated protein kinase 3
100456735 MYC; myc proto-oncogene protein
100458884 GAB1; GRB2-associated-binding protein 1 isoform X1
100460909 NRG3; pro-neuregulin-3, membrane-bound isoform isoform X1
100446528 NRG4; pro-neuregulin-4, membrane-bound isoform
100432846 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
100453779 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
103889133 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100174298 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
100173589 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
100437617 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100454279 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
100448114 AKT3; RAC-gamma serine/threonine-protein kinase
100442100 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
100456786 MTOR; serine/threonine-protein kinase mTOR
100462008 LOW QUALITY PROTEIN: ribosomal protein S6 kinase beta-1
100459428 RPS6KB2; ribosomal protein S6 kinase beta-2
100456988 RPS6KB1; LOW QUALITY PROTEIN: ribosomal protein S6 kinase beta-1
100455169 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1
100454097 BAD; bcl2-associated agonist of cell death
100447772 GSK3B; glycogen synthase kinase-3 beta isoform X1
100449905 CDKN1B; cyclin-dependent kinase inhibitor 1B
100453682 CDKN1A; cyclin-dependent kinase inhibitor 1
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K07365 NCK1; NCK adaptor protein 1
K19862 NCK2; NCK adaptor protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04375 ELK1; ETS domain-containing protein Elk-1
K09783 BTC; betacellulin
K08523 HBEGF; heparin-binding EGF-like growth factor
K09784 EREG; epiregulin
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K09593 GAB1; GRB2-associated-binding protein 1
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
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04014 Ras signaling pathway [PATH:pon04014]
|
04015 Rap1 signaling pathway [PATH:pon04015]
|
04310 Wnt signaling pathway [PATH:pon04310]
|
04330 Notch signaling pathway [PATH:pon04330]
|
04340 Hedgehog signaling pathway [PATH:pon04340]
|
04341 Hedgehog signaling pathway - fly
|
04350 TGF-beta signaling pathway [PATH:pon04350]
|
04390 Hippo signaling pathway [PATH:pon04390]
|
04391 Hippo signaling pathway - fly
|
04392 Hippo signaling pathway - multiple species [PATH:pon04392]
|
04370 VEGF signaling pathway [PATH:pon04370]
|
04371 Apelin signaling pathway [PATH:pon04371]
|
04630 JAK-STAT signaling pathway [PATH:pon04630]
|
04064 NF-kappa B signaling pathway [PATH:pon04064]
|
04668 TNF signaling pathway [PATH:pon04668]
|
04066 HIF-1 signaling pathway [PATH:pon04066]
|
04068 FoxO signaling pathway [PATH:pon04068]
|
04020 Calcium signaling pathway [PATH:pon04020]
|
04070 Phosphatidylinositol signaling system [PATH:pon04070]
|
04072 Phospholipase D signaling pathway [PATH:pon04072]
|
04071 Sphingolipid signaling pathway [PATH:pon04071]
|
04024 cAMP signaling pathway [PATH:pon04024]
|
04022 cGMP-PKG signaling pathway [PATH:pon04022]
|
04151 PI3K-Akt signaling pathway [PATH:pon04151]
|
04152 AMPK signaling pathway [PATH:pon04152]
|
04150 mTOR signaling pathway [PATH:pon04150]
|
04075 Plant hormone signal transduction
|
|
|
09133 Signaling molecules and interaction
|
|
|
09140 Cellular Processes
|
|
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09150 Organismal Systems
|
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09151 Immune system
|
04640 Hematopoietic cell lineage [PATH:pon04640]
|
04610 Complement and coagulation cascades [PATH:pon04610]
|
04611 Platelet activation [PATH:pon04611]
|
04613 Neutrophil extracellular trap formation [PATH:pon04613]
|
04620 Toll-like receptor signaling pathway [PATH:pon04620]
|
04624 Toll and Imd signaling pathway
|
04621 NOD-like receptor signaling pathway [PATH:pon04621]
|
04622 RIG-I-like receptor signaling pathway [PATH:pon04622]
|
04623 Cytosolic DNA-sensing pathway [PATH:pon04623]
|
04625 C-type lectin receptor signaling pathway [PATH:pon04625]
|
04650 Natural killer cell mediated cytotoxicity [PATH:pon04650]
|
04612 Antigen processing and presentation [PATH:pon04612]
|
04660 T cell receptor signaling pathway [PATH:pon04660]
|
112128523 uncharacterized protein LOC112128523
100440740 CD3D; T-cell surface glycoprotein CD3 delta chain
100440004 CD3E; T-cell surface glycoprotein CD3 epsilon chain
100440370 CD3G; T-cell surface glycoprotein CD3 gamma chain isoform X2
100458470 CD247; T-cell surface glycoprotein CD3 zeta chain isoform X1
100452381 CD4; T-cell surface glycoprotein CD4 isoform X3
100454128 CD8A; T-cell surface glycoprotein CD8 alpha chain isoform X1
100451669 CD8B; T-cell surface glycoprotein CD8 beta chain isoform X1
100446144 PTPRC; receptor-type tyrosine-protein phosphatase C isoform X1
100436326 LCK; LOW QUALITY PROTEIN: tyrosine-protein kinase Lck
100439712 FYN; tyrosine-protein kinase Fyn isoform X1
100451782 tyrosine-protein kinase ZAP-70 isoform X1
100456827 LCP2; lymphocyte cytosolic protein 2
100453027 LAT; linker for activation of T-cells family member 1 isoform X2
100459632 ITK; tyrosine-protein kinase ITK/TSK
100457311 TEC; tyrosine-protein kinase Tec
100171550 NCK1; cytoplasmic protein NCK1
100452789 NCK2; cytoplasmic protein NCK2 isoform X1
100442703 VAV3; guanine nucleotide exchange factor VAV3
100171723 VAV2; guanine nucleotide exchange factor VAV2
100447155 VAV1; proto-oncogene vav isoform X1
100431748 GRAP2; GRB2-related adapter protein 2 isoform X1
100173972 GRB2; growth factor receptor-bound protein 2
100449316 PAK1; serine/threonine-protein kinase PAK 1 isoform X1
100439815 PAK2; serine/threonine-protein kinase PAK 2
100294571 PAK3; serine/threonine-protein kinase PAK 3
100457556 PAK4; serine/threonine-protein kinase PAK 4 isoform X1
100174593 PAK7; serine/threonine-protein kinase PAK 7
100172971 PAK6; serine/threonine-protein kinase PAK 6
100171605 RHOA; transforming protein RhoA precursor
100438199 CDC42; cell division control protein 42 homolog
100444925 DLG1; disks large homolog 1 isoform X1
100449269 MAPK14; mitogen-activated protein kinase 14 isoform X2
100449853 MAPK13; mitogen-activated protein kinase 13 isoform X1
100437263 MAPK12; mitogen-activated protein kinase 12 isoform X1
100438358 MAPK11; mitogen-activated protein kinase 11
100450941 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2
100174530 PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
100455542 PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
100436675 PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X9
100461146 PPP3R2; calcineurin subunit B type 2
103889825 PPP3R1; calcineurin subunit B type 1
100436209 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1
100450332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1
100458008 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X3
100434331 SOS2; son of sevenless homolog 2 isoform X1
100458733 SOS1; son of sevenless homolog 1 isoform X1
100451529 RASGRP1; RAS guanyl-releasing protein 1 isoform X1
100459427 HRAS; GTPase HRas
100462513 KRAS; GTPase KRas isoform X1
100174317 NRAS; GTPase NRas precursor
100173732 RAF1; RAF proto-oncogene serine/threonine-protein kinase
100446021 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
100450988 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
100169740 MAPK1; mitogen-activated protein kinase 1 isoform X1
100431824 MAPK3; LOW QUALITY PROTEIN: mitogen-activated protein kinase 3
100462290 FOS; proto-oncogene c-Fos
100450292 JUN; transcription factor AP-1
100443896 PRKCQ; protein kinase C theta type
100461490 CARD11; caspase recruitment domain-containing protein 11
100446273 BCL10; B-cell lymphoma/leukemia 10 isoform X1
100452420 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1
100171454 MAP3K7; mitogen-activated protein kinase kinase kinase 7
100431600 MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X2
100174482 MAPK10; mitogen-activated protein kinase 10
100459133 MAPK9; mitogen-activated protein kinase 9 isoform X1
100437424 MAPK8; mitogen-activated protein kinase 8 isoform X1
100174735 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
100440586 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X3
100449496 IKBKG; NF-kappa-B essential modulator isoform X5
100461595 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
100456049 RELA; transcription factor p65
100459445 NF-kappa-B inhibitor alpha
100454648 NFKBIB; NF-kappa-B inhibitor beta
100446325 NFKBIE; LOW QUALITY PROTEIN: NF-kappa-B inhibitor epsilon
100450920 CD28; T-cell-specific surface glycoprotein CD28 isoform X1
100450190 ICOS; inducible T-cell costimulator isoform X1
100434130 CD40LG; CD40 ligand isoform X1
100174298 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
100173589 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
100437617 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100432846 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
100453779 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
103889133 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100452403 LOW QUALITY PROTEIN: 3-phosphoinositide-dependent protein kinase 1
112129400 LOW QUALITY PROTEIN: putative 3-phosphoinositide-dependent protein kinase 2
100454279 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
100448114 AKT3; RAC-gamma serine/threonine-protein kinase
100442100 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
103889401 MAP3K8; mitogen-activated protein kinase kinase kinase 8
100436201 MAP3K14; mitogen-activated protein kinase kinase kinase 14
100447772 GSK3B; glycogen synthase kinase-3 beta isoform X1
100462318 PDCD1; programmed cell death protein 1
100449582 CTLA4; cytotoxic T-lymphocyte protein 4 isoform X1
100448471 PTPN6; tyrosine-protein phosphatase non-receptor type 6
100440983 PTPN11; tyrosine-protein phosphatase non-receptor type 11 isoform X1
100437405 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
100461606 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
100173260 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
100437928 PPP2R1B; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1
100436819 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X2
100443527 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1
100174027 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
100462193 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma
100453295 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
100458345 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1
100450088 PPP2R3B; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1
100173941 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
100439998 PPP2R5B; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
100433271 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X1
100448353 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
100457751 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1
100452289 CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1
100455248 IL2; interleukin-2
100451705 IL4; interleukin-4 isoform X1
100450694 IL5; interleukin-5
100446386 IL10; interleukin-10
100444043 IFNG; interferon gamma
100447424 CSF2; granulocyte-macrophage colony-stimulating factor
100447558 TNF; tumor necrosis factor
100443314 CDK4; cyclin-dependent kinase 4 isoform X2
|
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06453 CD3Z; CD3Z antigen, zeta polypeptide
K06454 CD4; T-cell surface glycoprotein CD4
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K06478 PTPRC; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07361 LCP2; lymphocyte cytosolic protein 2
K07362 LAT; linker for activation of T cells family member 1
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
K07365 NCK1; NCK adaptor protein 1
K19862 NCK2; NCK adaptor protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K07366 GRAP2; GRB2-related adaptor protein 2
K04364 GRB2; growth factor receptor-bound protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K04393 CDC42; cell division control protein 42
K12076 DLG1; disks large protein 1
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K04350 RASGRP1; RAS guanyl-releasing protein 1
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K07367 CARD11; caspase recruitment domain-containing protein 11
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K06470 CD28; CD28 antigen
K06713 ICOS; inducible T-cell co-stimulator
K03161 TNFSF5; tumor necrosis factor ligand superfamily member 5
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04415 MAP3K8; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06744 PDCD1; programmed cell death protein 1
K06538 CTLA4; cytotoxic T-lymphocyte-associated protein 4
K05697 PTPN6; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05443 IL10; interleukin 10
K04687 IFNG; interferon gamma
K05427 CSF2; granulocyte-macrophage colony-stimulating factor
K03156 TNF; tumor necrosis factor superfamily, member 2
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
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04658 Th1 and Th2 cell differentiation [PATH:pon04658]
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04659 Th17 cell differentiation [PATH:pon04659]
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04657 IL-17 signaling pathway [PATH:pon04657]
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04662 B cell receptor signaling pathway [PATH:pon04662]
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04664 Fc epsilon RI signaling pathway [PATH:pon04664]
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04666 Fc gamma R-mediated phagocytosis [PATH:pon04666]
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04670 Leukocyte transendothelial migration [PATH:pon04670]
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04672 Intestinal immune network for IgA production [PATH:pon04672]
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04062 Chemokine signaling pathway [PATH:pon04062]
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09152 Endocrine system
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09153 Circulatory system
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09154 Digestive system
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09155 Excretory system
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09156 Nervous system
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09157 Sensory system
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09158 Development and regeneration
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04320 Dorso-ventral axis formation
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04360 Axon guidance [PATH:pon04360]
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100441611 NTNG1; netrin-G1 isoform X1
100445349 NTNG2; netrin-G2 isoform X1
100443780 LRRC4C; leucine-rich repeat-containing protein 4C
100439478 LRRC4; leucine-rich repeat-containing protein 4
100456320 NTN1; netrin-1
100450904 NTN3; netrin-3
100172474 NTN4; netrin-4 precursor
100442362 DCC; netrin receptor DCC
100450941 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2
100457650 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
100450201 TRPC1; short transient receptor potential channel 1 isoform X3
100454158 TRPC3; short transient receptor potential channel 3 isoform X1
100453863 TRPC4; short transient receptor potential channel 4 isoform X2
100437515 TRPC5; short transient receptor potential channel 5
100455441 TRPC6; short transient receptor potential channel 6 isoform X1
100174530 PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
100455542 PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
100436675 PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X9
100461146 PPP3R2; calcineurin subunit B type 2
103889825 PPP3R1; calcineurin subunit B type 1
100450332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1
100458008 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X3
100461543 NFATC4; LOW QUALITY PROTEIN: nuclear factor of activated T-cells, cytoplasmic 4
100447959 PTK2; focal adhesion kinase 1 isoform X1
100439712 FYN; tyrosine-protein kinase Fyn isoform X1
100436498 SRC; proto-oncogene tyrosine-protein kinase Src isoform X1
100443271 RAC1; ras-related C3 botulinum toxin substrate 1
100431483 RAC2; ras-related C3 botulinum toxin substrate 2
112129584 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1
100438199 CDC42; cell division control protein 42 homolog
100174330 ABLIM1; actin-binding LIM protein 1
100173729 ABLIM3; actin-binding LIM protein 3
100455017 ABLIM2; actin-binding LIM protein 2 isoform X1
100171550 NCK1; cytoplasmic protein NCK1
100449316 PAK1; serine/threonine-protein kinase PAK 1 isoform X1
100439815 PAK2; serine/threonine-protein kinase PAK 2
100294571 PAK3; serine/threonine-protein kinase PAK 3
100457556 PAK4; serine/threonine-protein kinase PAK 4 isoform X1
100174593 PAK7; serine/threonine-protein kinase PAK 7
100172971 PAK6; serine/threonine-protein kinase PAK 6
100171605 RHOA; transforming protein RhoA precursor
100432582 ROCK1; rho-associated protein kinase 1
100461801 ROCK2; rho-associated protein kinase 2 isoform X1
100447821 UNC5D; netrin receptor UNC5D isoform X1
100449535 UNC5B; netrin receptor UNC5B isoform X1
100443113 UNC5C; netrin receptor UNC5C
100457928 UNC5A; netrin receptor UNC5A
100440983 PTPN11; tyrosine-protein phosphatase non-receptor type 11 isoform X1
100433845 RGMA; repulsive guidance molecule A
100448839 NEO1; neogenin isoform X1
100455740 MYL5; myosin light chain 5 isoform X2
100172462 MYL9; myosin regulatory light polypeptide 9
100450310 myosin regulatory light chain 12B
100172271 MYL12A; myosin regulatory light chain 12A
100432987 myosin regulatory light chain 12B isoform X1
100457621 ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1
100432621 LRIG2; leucine-rich repeats and immunoglobulin-like domains protein 2 isoform X1
100448360 EFNA1; ephrin-A1
100448970 EFNA3; ephrin-A3 isoform X1
100449916 EFNA4; ephrin-A4 isoform X2
100451193 EFNA5; ephrin-A5
112130075 EFNA2; ephrin-A2
100437201 EFNB2; ephrin-B2
100458568 EFNB3; ephrin-B3
100443625 EFNB1; ephrin-B1
100459900 EPHA1; ephrin type-A receptor 1
100451664 EPHA2; ephrin type-A receptor 2
100439679 EPHA3; ephrin type-A receptor 3
100458982 EPHA4; ephrin type-A receptor 4 isoform X1
100438830 EPHA5; ephrin type-A receptor 5 isoform X1
100450926 EPHA6; ephrin type-A receptor 6 isoform X1
100449745 EPHA7; ephrin type-A receptor 7 isoform X1
100435582 EPHA8; ephrin type-A receptor 8
100450679 EPHB1; ephrin type-B receptor 1
100432564 EPHB2; ephrin type-B receptor 2 isoform X1
100453908 EPHB3; ephrin type-B receptor 3
100461743 EPHB4; ephrin type-B receptor 4 isoform X1
100453089 EPHB6; ephrin type-B receptor 6
100453216 ABL1; tyrosine-protein kinase ABL1 isoform X1
100439142 ENAH; LOW QUALITY PROTEIN: protein enabled homolog
100172162 RASA1; ras GTPase-activating protein 1
100171841 NGEF; ephexin-1
100459427 HRAS; GTPase HRas
100462513 KRAS; GTPase KRas isoform X1
100174317 NRAS; GTPase NRas precursor
100169740 MAPK1; mitogen-activated protein kinase 1 isoform X1
100431824 MAPK3; LOW QUALITY PROTEIN: mitogen-activated protein kinase 3
100452789 NCK2; cytoplasmic protein NCK2 isoform X1
100445111 RGS3; regulator of G-protein signaling 3 isoform X1
100173045 CXCL12; stromal cell-derived factor 1 precursor
100451032 CXCR4; C-X-C chemokine receptor type 4
100456074 GNAI3; guanine nucleotide-binding protein G(k) subunit alpha
100172679 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1
100458137 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 isoform X1
100459557 SLIT1; slit homolog 1 protein
100434105 SLIT2; slit homolog 2 protein isoform X1
100452700 SLIT3; slit homolog 3 protein isoform X1
100459973 ROBO1; roundabout homolog 1 isoform X2
100460588 ROBO2; roundabout homolog 2 isoform X1
100172083 ROBO3; roundabout homolog 3
100462396 SRGAP1; SLIT-ROBO Rho GTPase-activating protein 1 isoform X1
100449084 SRGAP2; SLIT-ROBO Rho GTPase-activating protein 2 isoform X2
100437356 SRGAP3; SLIT-ROBO Rho GTPase-activating protein 3 isoform X1
100171774 SEMA3C; semaphorin-3C precursor
100456971 SEMA3D; semaphorin-3D
100458068 SEMA3A; semaphorin-3A
100460264 SEMA3E; semaphorin-3E
100461952 SEMA3G; semaphorin-3G
100458869 SEMA3F; semaphorin-3F isoform X1
100460340 SEMA3B; semaphorin-3B isoform X1
100436265 PLXNA4; plexin-A4 isoform X1
100450590 PLXNA3; plexin-A3 isoform X1
100437578 PLXNA2; plexin-A2 isoform X2
100437718 PLXNA1; plexin-A1
100171901 NRP1; neuropilin-1 precursor
100437141 L1CAM; neural cell adhesion molecule L1
100432626 LIMK1; LIM domain kinase 1
100460494 LIMK2; LIM domain kinase 2 isoform X1
100454363 CFL2; cofilin-2 isoform X1
103891788 CFL1; cofilin-1 isoform X1
100462266 RHOD; rho-related GTP-binding protein RhoD
100439634 RND1; rho-related GTP-binding protein Rho6
100447871 FES; tyrosine-protein kinase Fes/Fps isoform X2
100454014 DPYSL5; dihydropyrimidinase-related protein 5
100172763 DPYSL2; dihydropyrimidinase-related protein 2
100442658 CDK5; cyclin-dependent-like kinase 5
100447772 GSK3B; glycogen synthase kinase-3 beta isoform X1
100446769 SEMA4B; semaphorin-4B
100445454 SEMA4C; semaphorin-4C
100435299 SEMA4D; semaphorin-4D
100172970 SEMA4A; semaphorin-4A precursor
100454952 SEMA4G; semaphorin-4G isoform X1
100458612 SEMA4F; semaphorin-4F isoform X1
100455967 SEMA5B; semaphorin-5B
100448412 SEMA5A; semaphorin-5A
100457516 SEMA6C; semaphorin-6C isoform X1
100173330 SEMA6D; semaphorin-6D precursor
100443615 SEMA6A; semaphorin-6A isoform X1
100452051 SEMA6B; semaphorin-6B
100441548 PLXNB3; plexin-B3 isoform X1
100172633 PLXNB2; plexin-B2 precursor
100455234 PLXNB1; LOW QUALITY PROTEIN: plexin-B1
100137030 MET; hepatocyte growth factor receptor precursor
100173732 RAF1; RAF proto-oncogene serine/threonine-protein kinase
100440912 RRAS; ras-related protein R-Ras isoform X2
100451776 SEMA7A; semaphorin-7A
100445880 PLXNC1; plexin-C1
100172223 ITGB1; integrin beta-1 precursor
100461003 SHH; sonic hedgehog protein isoform X1
100452966 SMO; smoothened homolog
100434355 PRKCA; protein kinase C alpha type isoform X1
100173674 ILK; integrin-linked protein kinase
100458622 BOC; brother of CDO isoform X1
100174132 WNT5B; protein Wnt-5b precursor
100447525 WNT5A; protein Wnt-5a isoform X1
100457942 FZD3; frizzled-3
100447775 RYK; tyrosine-protein kinase RYK isoform X1
100433531 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1
100172212 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha
100462386 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1
100436747 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1
100436330 WNT4; protein Wnt-4
100432846 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
100453779 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
103889133 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100174298 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
100173589 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
100437617 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100452403 LOW QUALITY PROTEIN: 3-phosphoinositide-dependent protein kinase 1
112129400 LOW QUALITY PROTEIN: putative 3-phosphoinositide-dependent protein kinase 2
100431669 PARD3; partitioning defective 3 homolog isoform X3
100174126 PRKCZ; protein kinase C zeta type
100446406 PARD6A; partitioning defective 6 homolog alpha isoform X1
100446683 PARD6B; partitioning defective 6 homolog beta
112129943 PARD6G; partitioning defective 6 homolog gamma
100434184 SSH3; protein phosphatase Slingshot homolog 3 isoform X1
100435219 SSH2; protein phosphatase Slingshot homolog 2 isoform X1
100443917 SSH1; protein phosphatase Slingshot homolog 1 isoform X1
100434378 BMP7; bone morphogenetic protein 7
100443944 GDF7; growth/differentiation factor 7
100441517 BMPR2; bone morphogenetic protein receptor type-2
100444576 BMPR1B; bone morphogenetic protein receptor type-1B isoform X1
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K07522 NTNG1; netrin-G1
K16359 NTNG2; netrin-G2
K07523 LRRC4C; netrin-G1 ligand
K16351 LRRC4; netrin-G2 ligand
K06843 NTN1; netrin 1
K06844 NTN3; netrin 3
K06845 NTN4; netrin 4
K06765 DCC; deleted in colorectal carcinoma
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04964 TRPC1; transient receptor potential cation channel subfamily C member 1
K04966 TRPC3; transient receptor potential cation channel subfamily C member 3
K04967 TRPC4; transient receptor potential cation channel subfamily C member 4
K04968 TRPC5; transient receptor potential cation channel subfamily C member 5
K04969 TRPC6; transient receptor potential cation channel subfamily C member 6
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K07520 ABLIM; actin-binding LIM protein
K07520 ABLIM; actin-binding LIM protein
K07520 ABLIM; actin-binding LIM protein
K07365 NCK1; NCK adaptor protein 1
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K07521 UNC5; netrin receptor unc-5
K07521 UNC5; netrin receptor unc-5
K07521 UNC5; netrin receptor unc-5
K07521 UNC5; netrin receptor unc-5
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K23096 RGMA; repulsive guidance molecule A
K06766 NEO1; neogenin
K12753 MYL5; myosin regulatory light chain 5
K12755 MYL9; myosin regulatory light chain 9
K12757 MYL12; myosin regulatory light chain 12
K12757 MYL12; myosin regulatory light chain 12
K12757 MYL12; myosin regulatory light chain 12
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K24609 LRIG2; leucine-rich repeats and immunoglobulin-like domains protein 2
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05463 EFNB; ephrin-B
K05463 EFNB; ephrin-B
K05463 EFNB; ephrin-B
K05102 EPHA1; Eph receptor A1 [EC:2.7.10.1]
K05103 EPHA2; Eph receptor A2 [EC:2.7.10.1]
K05104 EPHA3; Eph receptor A3 [EC:2.7.10.1]
K05105 EPHA4; Eph receptor A4 [EC:2.7.10.1]
K05106 EPHA5; Eph receptor A5 [EC:2.7.10.1]
K05107 EPHA6; Eph receptor A6 [EC:2.7.10.1]
K05108 EPHA7; EphA7 [EC:2.7.10.1]
K05109 EPHA8; Eph receptor A8 [EC:2.7.10.1]
K05110 EPHB1; Eph receptor B1 [EC:2.7.10.1]
K05111 EPHB2; Eph receptor B2 [EC:2.7.10.1]
K05112 EPHB3; Eph receptor B3 [EC:2.7.10.1]
K05113 EPHB4; Eph receptor B4 [EC:2.7.10.1]
K05114 EPHB6; Eph receptor B6 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K05746 ENAH; enabled
K04352 RASA1; Ras GTPase-activating protein 1
K07525 NGEF; neuronal guanine nucleotide exchange factor
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K19862 NCK2; NCK adaptor protein 2
K07524 RGS3; regulator of G-protein signalling 3
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K06838 SLIT1; slit 1
K06839 SLIT2; slit 2
K06850 SLIT3; slit 3
K06753 ROBO1; roundabout, axon guidance receptor 1
K06754 ROBO2; roundabout, axon guidance receptor 2
K06755 ROBO3; roundabout, axon guidance receptor 3
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein
K07526 SRGAP; SLIT-ROBO Rho GTPase activating protein
K06840 SEMA3; semaphorin 3
K06840 SEMA3; semaphorin 3
K06840 SEMA3; semaphorin 3
K06840 SEMA3; semaphorin 3
K06840 SEMA3; semaphorin 3
K06840 SEMA3; semaphorin 3
K06840 SEMA3; semaphorin 3
K06820 PLXNA; plexin A
K06820 PLXNA; plexin A
K06820 PLXNA; plexin A
K06820 PLXNA; plexin A
K06724 NRP1; neuropilin 1
K06550 L1CAM; L1 cell adhesion molecule
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05765 CFL; cofilin
K05765 CFL; cofilin
K07530 RHOD; Ras homolog gene family, member D
K07531 RND1; Rho family GTPase 1
K07527 FES; tyrosine-protein kinase Fes/Fps [EC:2.7.10.2]
K07529 DPYSL5; dihydropyrimidinase-like 5
K07528 DPYSL2; dihydropyrimidinase-like 2
K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06521 SEMA4; semaphorin 4
K06521 SEMA4; semaphorin 4
K06521 SEMA4; semaphorin 4
K06521 SEMA4; semaphorin 4
K06521 SEMA4; semaphorin 4
K06521 SEMA4; semaphorin 4
K06841 SEMA5; semaphorin 5
K06841 SEMA5; semaphorin 5
K06842 SEMA6; semaphorin 6
K06842 SEMA6; semaphorin 6
K06842 SEMA6; semaphorin 6
K06842 SEMA6; semaphorin 6
K06821 PLXNB; plexin B
K06821 PLXNB; plexin B
K06821 PLXNB; plexin B
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07829 RRAS; Ras-related protein R-Ras
K06529 SEMA7; semaphorin 7
K06572 PLXNC; plexin C
K05719 ITGB1; integrin beta 1
K11988 SHH; sonic hedgehog
K06226 SMO; smoothened
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K20020 BOC; brother of CDO
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K02329 FZD3; frizzled 3
K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04237 PARD3; partitioning defective protein 3
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
K16621 BMP7; bone morphogenetic protein 7
K20013 GDF7; growth differentiation factor 7
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
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04361 Axon regeneration
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04380 Osteoclast differentiation [PATH:pon04380]
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09149 Aging
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09159 Environmental adaptation
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09160 Human Diseases
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Pongo abelii (Sumatran orangutan)