KEGG Orthology (KO) - Rhincodon typus (whale shark)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:rtp04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:rtp04012]
       109929559 egf; pro-epidermal growth factor
       109925311 tgfa; protransforming growth factor alpha
       109927384 LOW QUALITY PROTEIN: epidermal growth factor receptor-like
       109930473 receptor tyrosine-protein kinase erbB-2-like
       109912305 LOW QUALITY PROTEIN: 1-phosphatidylinositol 4
       109939029 plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
       109928136 LOW QUALITY PROTEIN: 1-phosphatidylinositol 4
       109922295 camk2d; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1
       109912036 calcium/calmodulin-dependent protein kinase type II subunit beta-like
       109913788 LOW QUALITY PROTEIN: protein kinase C beta type-like
       109922666 cbl; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase CBL
       109911921 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase CBL-B-like
       109924857 signal transducer and activator of transcription 5B-like
       109929795 signal transducer and activator of transcription 5B-like
       109921818 proto-oncogene tyrosine-protein kinase Src
       109923915 crkl; crk-like protein
       109916685 crk; adapter molecule crk
       109930229 LOW QUALITY PROTEIN: tyrosine-protein kinase ABL1-like
       109929176 Abelson tyrosine-protein kinase 2-like
       109917774 nck1; cytoplasmic protein NCK1 isoform X1
       109936440 nck2; cytoplasmic protein NCK2
       109939010 LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 1-like
       109911747 pak2; serine/threonine-protein kinase PAK 2
       109911891 LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 3-like
       109921489 serine/threonine-protein kinase PAK 5-like
       109938171 pak4; serine/threonine-protein kinase PAK 4
       109935293 pak5; serine/threonine-protein kinase PAK 5
       109913245 serine/threonine-protein kinase PAK 4-like
       109935414 map2k4; dual specificity mitogen-activated protein kinase kinase 4
       109911816 map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1
       109927876 mapk10; mitogen-activated protein kinase 10 isoform X1
       109917844 mitogen-activated protein kinase 9 isoform X1
       109917855 mitogen-activated protein kinase 8 isoform X1
       109913093 transcription factor AP-1-like
       109925743 jun; transcription factor AP-1
       109923001 transcription factor AP-1-like
       109922435 probetacellulin-like
       109933026 proheparin-binding EGF-like growth factor
       109925072 proepiregulin-like
       109912652 pro-neuregulin-2
       109923881 LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-4-like
       109937865 shc2; SHC-transforming protein 2
       109933522 grb2; growth factor receptor-bound protein 2
       109923392 son of sevenless homolog 2-like
       109919917 sos1; son of sevenless homolog 1
       109922179 son of sevenless homolog 2-like
       109915744 GTPase HRas
       109919287 GTPase HRas-like
       109931543 kras; GTPase KRas isoform X1
       109917328 nras; GTPase NRas
       109925193 serine/threonine-protein kinase A-Raf-like
       109917885 braf; LOW QUALITY PROTEIN: serine/threonine-protein kinase B-raf
       109911534 raf1; RAF proto-oncogene serine/threonine-protein kinase
       109922810 map2k1; dual specificity mitogen-activated protein kinase kinase 1
       109923051 dual specificity mitogen-activated protein kinase kinase 1-like
       109911767 map2k2; dual specificity mitogen-activated protein kinase kinase 2
       109918415 mitogen-activated protein kinase 1
       109916636 myc proto-oncogene protein-like
       109923817 transcriptional regulator Myc-B-like
       109924954 gab1; GRB2-associated-binding protein 1 isoform X1
       109923018 LOW QUALITY PROTEIN: pro-neuregulin-3
       109915990 pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       109915713 pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
       109921900 LOW QUALITY PROTEIN: phosphatidylinositol 4
       109916739 LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit alpha-like
       109917303 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       109931632 RAC-beta serine/threonine-protein kinase
       109915958 RAC-alpha serine/threonine-protein kinase-like isoform X1
       109916533 RAC-gamma serine/threonine-protein kinase isoform X1
       109914403 serine/threonine-protein kinase mTOR
       109911139 ribosomal protein S6 kinase beta-1-like isoform X1
       109910841 glycogen synthase kinase-3 beta
       109931217 cyclin-dependent kinase inhibitor 1B-like
       109923052 cdkn1b; cyclin-dependent kinase inhibitor 1B
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K11224 STAT5B; signal transducer and activator of transcription 5B
K11224 STAT5B; signal transducer and activator of transcription 5B
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K07365 NCK1; NCK adaptor protein 1
K19862 NCK2; NCK adaptor protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04448 JUN; transcription factor AP-1
K04448 JUN; transcription factor AP-1
K09783 BTC; betacellulin
K08523 HBEGF; heparin-binding EGF-like growth factor
K09784 EREG; epiregulin
K05456 NRG2; neuregulin 2
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K17447 SHC2; SHC-transforming protein 2
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K04377 MYC; Myc proto-oncogene protein
K09593 GAB1; GRB2-associated-binding protein 1
K05457 NRG3; neuregulin 3
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04310 Wnt signaling pathway [PATH:rtp04310]
     04330 Notch signaling pathway [PATH:rtp04330]
     04340 Hedgehog signaling pathway [PATH:rtp04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:rtp04350]
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species
     04370 VEGF signaling pathway [PATH:rtp04370]
     04371 Apelin signaling pathway [PATH:rtp04371]
     04630 JAK-STAT signaling pathway
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway [PATH:rtp04068]
       109936507 transforming growth factor beta-3-like
       109911779 tgfb2; transforming growth factor beta-2
       109921206 tgfb3; transforming growth factor beta-3
       109921531 TGF-beta receptor type-1-like
       109916891 LOW QUALITY PROTEIN: TGF-beta receptor type-2-like
       109926924 TGF-beta receptor type-2-like isoform X1
       109911226 smad4; mothers against decapentaplegic homolog 4 isoform X1
       109928938 mothers against decapentaplegic homolog 4-like
       109922540 mothers against decapentaplegic homolog 4-like
       109936169 smad3; mothers against decapentaplegic homolog 3
       109931437 stk11; serine/threonine-protein kinase STK11 isoform X1
       109937292 5'-AMP-activated protein kinase catalytic subunit alpha-2
       109914373 5'-AMP-activated protein kinase subunit beta-2-like isoform X1
       109917053 5'-AMP-activated protein kinase subunit beta-1-like isoform X1
       109917049 LOW QUALITY PROTEIN: 5'-AMP-activated protein kinase subunit beta-1-like
       109913511 5'-AMP-activated protein kinase subunit gamma-2-like isoform X1
       109918573 5'-AMP-activated protein kinase subunit gamma-1-like
       109923993 5'-AMP-activated protein kinase subunit gamma-1-like
       109922887 5'-AMP-activated protein kinase subunit gamma-1-like
       109936130 5'-AMP-activated protein kinase subunit gamma-2-like
       109933967 nlk; serine/threonine-protein kinase NLK
       109923386 skp2; S-phase kinase-associated protein 2
       109934681 E3 ubiquitin-protein ligase Mdm2-like
       109919566 setd7; histone-lysine N-methyltransferase SETD7
       109916767 CREB-binding protein-like
       109934587 LOW QUALITY PROTEIN: histone acetyltransferase p300-like
       109912079 sirt1; LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-1
       109915840 usp7; ubiquitin carboxyl-terminal hydrolase 7
       109924526 solute carrier family 2
       109927876 mapk10; mitogen-activated protein kinase 10 isoform X1
       109917844 mitogen-activated protein kinase 9 isoform X1
       109917855 mitogen-activated protein kinase 8 isoform X1
       109919516 serine/threonine-protein kinase 3/4
       109914145 igf1; insulin-like growth factor I
       109921259 ins; insulin
       109916967 insulin receptor substrate 1-like
       109924087 LOW QUALITY PROTEIN: insulin receptor substrate 1-B-like
       109921559 irs2; insulin receptor substrate 2
       109919326 LOW QUALITY PROTEIN: insulin receptor substrate 2-A-like
       109915990 pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       109915713 pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
       109921900 LOW QUALITY PROTEIN: phosphatidylinositol 4
       109916739 LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit alpha-like
       109917303 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       109934300 pdpk1; LOW QUALITY PROTEIN: 3-phosphoinositide-dependent protein kinase 1
       109918795 chuk; inhibitor of nuclear factor kappa-B kinase subunit alpha
       109927975 ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
       109913977 pten; LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
       109931632 RAC-beta serine/threonine-protein kinase
       109915958 RAC-alpha serine/threonine-protein kinase-like isoform X1
       109916533 RAC-gamma serine/threonine-protein kinase isoform X1
       109911769 serine/threonine-protein kinase Sgk1-like
       109926745 serine/threonine-protein kinase Sgk1-like isoform X1
       109934538 serine/threonine-protein kinase Sgk1-like isoform X1
       109911055 sgk2; serine/threonine-protein kinase Sgk2 isoform X1
       109926926 foxo1; forkhead box protein O1 isoform X1
       109921049 forkhead box protein O6-like
       109928072 foxo3; forkhead box protein O3
       109918547 forkhead box protein O3-like
       109912450 LOW QUALITY PROTEIN: homer protein homolog 3-like
       109930421 homer1; homer protein homolog 1
       109935778 casein kinase I
       109925335 interleukin-6-like
       109925317 il6; interleukin-6 isoform X1
       109918245 il10; interleukin-10
       109928447 stat3; signal transducer and activator of transcription 3
       109929559 egf; pro-epidermal growth factor
       109927384 LOW QUALITY PROTEIN: epidermal growth factor receptor-like
       109933522 grb2; growth factor receptor-bound protein 2
       109923392 son of sevenless homolog 2-like
       109919917 sos1; son of sevenless homolog 1
       109922179 son of sevenless homolog 2-like
       109915744 GTPase HRas
       109919287 GTPase HRas-like
       109931543 kras; GTPase KRas isoform X1
       109917328 nras; GTPase NRas
       109917885 braf; LOW QUALITY PROTEIN: serine/threonine-protein kinase B-raf
       109911534 raf1; RAF proto-oncogene serine/threonine-protein kinase
       109925193 serine/threonine-protein kinase A-Raf-like
       109922810 map2k1; dual specificity mitogen-activated protein kinase kinase 1
       109923051 dual specificity mitogen-activated protein kinase kinase 1-like
       109911767 map2k2; dual specificity mitogen-activated protein kinase kinase 2
       109918415 mitogen-activated protein kinase 1
       109936687 mitogen-activated protein kinase 11-like
       109927220 mapk12; mitogen-activated protein kinase 12
       109932340 mitogen-activated protein kinase 13-like
       109932351 mitogen-activated protein kinase 14 isoform X1
       109914201 LOW QUALITY PROTEIN: mitogen-activated protein kinase 14B-like
       109923466 cyclin-dependent kinase 2-like isoform X1
       109926412 cyclin-dependent kinase 2-like
       109934225 prmt1; protein arginine N-methyltransferase 1
       109916400 forkhead box protein G1-like
       109922922 forkhead box protein G1-like
       109925235 foxg1; forkhead box protein G1
       109935081 ccnb1; G2/mitotic-specific cyclin-B1
       109914894 ccnb2; G2/mitotic-specific cyclin-B2
       109911281 ccnb3; G2/mitotic-specific cyclin-B3
       109919627 LOW QUALITY PROTEIN: G1/S-specific cyclin-D1-like
       109925537 G1/S-specific cyclin-D1-like
       109931888 G1/S-specific cyclin-D2-like
       109913131 ccng2; cyclin-G2
       109935914 cyclin-dependent kinase 4 inhibitor D-like
       109923052 cdkn1b; cyclin-dependent kinase inhibitor 1B
       109931217 cyclin-dependent kinase inhibitor 1B-like
       109915431 rbl2; retinoblastoma-like protein 2 isoform X1
       109910478 plk1; serine/threonine-protein kinase PLK1
       109932494 plk2; serine/threonine-protein kinase PLK2
       109920893 plk4; serine/threonine-protein kinase PLK4
       109911340 growth arrest and DNA damage-inducible protein GADD45 alpha-like
       109933624 gadd45g; growth arrest and DNA damage-inducible protein GADD45 gamma
       109926854 gadd45a; growth arrest and DNA damage-inducible protein GADD45 alpha
       109912678 LOW QUALITY PROTEIN: growth arrest and DNA damage-inducible protein GADD45 beta-like
       109930946 tumor necrosis factor ligand superfamily member 6-like
       109930950 tumor necrosis factor ligand superfamily member 6-like
       109930951 tumor necrosis factor ligand superfamily member 6-like
       109938453 tumor necrosis factor ligand superfamily member 10-like
       109920675 tumor necrosis factor ligand superfamily member 10-like
       109912665 B-cell lymphoma 6 protein homolog
       109932991 LOW QUALITY PROTEIN: B-cell lymphoma 6 protein homolog
       109924930 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
       109935590 bnip3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
       109925439 gabarap; gamma-aminobutyric acid receptor-associated protein
       109921630 gabarapl2; gamma-aminobutyric acid receptor-associated protein-like 2
       109918715 cat; catalase
       109920881 sod2; superoxide dismutase [Mn], mitochondrial
       109934178 atm; LOW QUALITY PROTEIN: serine-protein kinase ATM
       109913389 pck1; phosphoenolpyruvate carboxykinase, cytosolic [GTP]
       109937251 phosphoenolpyruvate carboxykinase
       109912270 glucose-6-phosphatase-like
       109912271 glucose-6-phosphatase-like
       109912272 glucose-6-phosphatase-like isoform X1
       109937261 g6pc3; glucose-6-phosphatase 3
       109936134 LOW QUALITY PROTEIN: Krueppel-like factor 2
       109911482 s1pr1; sphingosine 1-phosphate receptor 1
       109912735 s1pr4; sphingosine 1-phosphate receptor 4
       109930497 rag1; V(D)J recombination-activating protein 1
       109930494 rag2; LOW QUALITY PROTEIN: V(D)J recombination-activating protein 2
       109914364 F-box only protein 25-like
       109913601 fbxo32; F-box only protein 32
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K04526 INS; insulin
K16172 IRS1; insulin receptor substrate 1
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K07187 IRS2; insulin receptor substrate 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K09408 FOXO3; forkhead box protein O3
K17847 FOXO6; forkhead box protein O6
K15010 HOMER; homer
K15010 HOMER; homer
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05405 IL6; interleukin 6
K05443 IL10; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K09385 FOXG; forkhead box protein G
K09385 FOXG; forkhead box protein G
K09385 FOXG; forkhead box protein G
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10146 CCNG2; cyclin G2
K06623 CDKN2D; cyclin-dependent kinase inhibitor 2D
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K03781 katE; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
K10305 FBXO25_32; F-box protein 25/32
     04020 Calcium signaling pathway [PATH:rtp04020]
     04070 Phosphatidylinositol signaling system [PATH:rtp04070]
     04072 Phospholipase D signaling pathway
     04071 Sphingolipid signaling pathway
     04024 cAMP signaling pathway
     04022 cGMP-PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway [PATH:rtp04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:rtp04110]
       109919627 LOW QUALITY PROTEIN: G1/S-specific cyclin-D1-like
       109925537 G1/S-specific cyclin-D1-like
       109931888 G1/S-specific cyclin-D2-like
       109925336 cdk4; cyclin-dependent kinase 4
       109936365 cyclin-dependent kinase 6-like
       109920140 cyclin-dependent kinase 6-like
       109937908 rb1; LOW QUALITY PROTEIN: retinoblastoma-associated protein
       109919372 rbl1; retinoblastoma-like protein 1
       109915431 rbl2; retinoblastoma-like protein 2 isoform X1
       109930229 LOW QUALITY PROTEIN: tyrosine-protein kinase ABL1-like
       109936171 histone deacetylase 2
       109913967 probable histone deacetylase 1-B
       109915257 e2f1; transcription factor E2F1
       109929351 transcription factor E2F2-like
       109923152 e2f3; transcription factor E2F3
       109917377 e2f5; transcription factor E2F5
       109918432 e2f4; transcription factor E2F4 isoform X1
       109912302 transcription factor Dp-1-like isoform X1
       109932287 tfdp2; transcription factor Dp-2
       109910841 glycogen synthase kinase-3 beta
       109936507 transforming growth factor beta-3-like
       109911779 tgfb2; transforming growth factor beta-2
       109921206 tgfb3; transforming growth factor beta-3
       109914262 mothers against decapentaplegic homolog 2 isoform X1
       109936169 smad3; mothers against decapentaplegic homolog 3
       109911226 smad4; mothers against decapentaplegic homolog 4 isoform X1
       109928938 mothers against decapentaplegic homolog 4-like
       109922540 mothers against decapentaplegic homolog 4-like
       109916636 myc proto-oncogene protein-like
       109923817 transcriptional regulator Myc-B-like
       109926945 zbtb17; zinc finger and BTB domain-containing protein 17 isoform X1
       109914995 cdkn2c; cyclin-dependent kinase 4 inhibitor C
       109935914 cyclin-dependent kinase 4 inhibitor D-like
       109931217 cyclin-dependent kinase inhibitor 1B-like
       109912617 cyclin-dependent kinase inhibitor 1C-like
       109923052 cdkn1b; cyclin-dependent kinase inhibitor 1B
       109924247 ccne2; G1/S-specific cyclin-E2
       109932834 ccne1; G1/S-specific cyclin-E1 isoform X1
       109923466 cyclin-dependent kinase 2-like isoform X1
       109926412 cyclin-dependent kinase 2-like
       109912239 S-phase kinase-associated protein 1
       109934365 S-phase kinase-associated protein 1-like isoform X1
       109916300 cul1; cullin-1
       109921792 rbx1; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RBX1
       109923386 skp2; S-phase kinase-associated protein 2
       109916715 cyclin-A2-like
       109923733 ccna1; cyclin-A1
       109921699 cdc6; cell division control protein 6 homolog
       109939113 cdc45; cell division control protein 45 homolog isoform X1
       109913944 cdc7; cell division cycle 7-related protein kinase
       109928488 protein DBF4 homolog A-like isoform X1
       109911524 cdk1; cyclin-dependent kinase 1
       109935081 ccnb1; G2/mitotic-specific cyclin-B1
       109914894 ccnb2; G2/mitotic-specific cyclin-B2
       109911281 ccnb3; G2/mitotic-specific cyclin-B3
       109923609 M-phase inducer phosphatase 1-A-like
       109928665 14-3-3 protein beta/alpha-1-like
       109915867 14-3-3 protein beta/alpha-1
       109927423 14-3-3-like protein
       109935218 14-3-3 protein beta/alpha-1-like
       109916686 ywhae; 14-3-3 protein epsilon
       109918614 14-3-3 protein gamma-B
       109924564 14-3-3 protein gamma-1-like
       109910478 plk1; serine/threonine-protein kinase PLK1
       109921278 wee1; wee1-like protein kinase isoform X1
       109920944 wee1-like protein kinase 2-A
       109912981 ccnh; LOW QUALITY PROTEIN: cyclin-H
       109927171 cdk7; cyclin-dependent kinase 7
       109913405 LOW QUALITY PROTEIN: anaphase-promoting complex subunit 1-like
       109929700 anaphase-promoting complex subunit 1-like
       109914695 anapc2; LOW QUALITY PROTEIN: anaphase-promoting complex subunit 2
       109914857 LOW QUALITY PROTEIN: cell division cycle protein 27 homolog
       109932557 anapc4; LOW QUALITY PROTEIN: anaphase-promoting complex subunit 4
       109913952 anapc5; anaphase-promoting complex subunit 5 isoform X1
       109916704 cdc16; LOW QUALITY PROTEIN: cell division cycle protein 16 homolog
       109911396 anapc7; LOW QUALITY PROTEIN: anaphase-promoting complex subunit 7
       109920184 cdc23; cell division cycle protein 23 homolog
       109925514 cullin-7-like
       109931211 anapc11; anaphase-promoting complex subunit 11
       109921450 cdc26; anaphase-promoting complex subunit CDC26
       109914450 anapc13; anaphase-promoting complex subunit 13
       109927894 cdc20; cell division cycle protein 20 homolog
       109916342 securin-like
       109937248 LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 1B-like
       109923263 smc1a; structural maintenance of chromosomes protein 1A isoform X1
       109930775 smc3; LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 3
       109927345 stag2; cohesin subunit SA-2
       109922845 cohesin subunit SA-1-like
       109917382 cohesin subunit SA-2-like
       109934307 stag1; cohesin subunit SA-1 isoform X1
       109916220 double-strand-break repair protein rad21 homolog
       109924678 rad21; double-strand-break repair protein rad21 homolog isoform X1
       109932309 ttk; dual specificity protein kinase TTK
       109933534 mitotic checkpoint serine/threonine-protein kinase BUB1-like
       109933535 mitotic checkpoint serine/threonine-protein kinase BUB1-like
       109927467 bub3; mitotic checkpoint protein BUB3
       109930089 mad1l1; mitotic spindle assembly checkpoint protein MAD1
       109912975 mad2l2; LOW QUALITY PROTEIN: mitotic spindle assembly checkpoint protein MAD2B
       109922560 fzr1; fizzy-related protein homolog isoform X1
       109930947 LOW QUALITY PROTEIN: fizzy-related protein homolog
       109923255 dual specificity protein phosphatase CDC14A-like
       109919808 dual specificity protein phosphatase CDC14A-like isoform X1
       109934427 atr; serine/threonine-protein kinase ATR
       109934178 atm; LOW QUALITY PROTEIN: serine-protein kinase ATM
       109921452 chek1; serine/threonine-protein kinase Chk1
       109911275 chek2; serine/threonine-protein kinase Chk2
       109916767 CREB-binding protein-like
       109934587 LOW QUALITY PROTEIN: histone acetyltransferase p300-like
       109915842 LOW QUALITY PROTEIN: DNA-dependent protein kinase catalytic subunit-like
       109934681 E3 ubiquitin-protein ligase Mdm2-like
       109911340 growth arrest and DNA damage-inducible protein GADD45 alpha-like
       109933624 gadd45g; growth arrest and DNA damage-inducible protein GADD45 gamma
       109926854 gadd45a; growth arrest and DNA damage-inducible protein GADD45 alpha
       109912678 LOW QUALITY PROTEIN: growth arrest and DNA damage-inducible protein GADD45 beta-like
       109919937 pcna; proliferating cell nuclear antigen
       109923550 orc1; origin recognition complex subunit 1
       109923184 orc2; origin recognition complex subunit 2
       109910808 orc3; origin recognition complex subunit 3 isoform X1
       109912423 orc4; origin recognition complex subunit 4 isoform X1
       109926881 orc5; origin recognition complex subunit 5 isoform X1
       109934885 orc6; origin recognition complex subunit 6 isoform X1
       109915245 mcm2; DNA replication licensing factor MCM2 isoform X1
       109918292 mcm3; DNA replication licensing factor MCM3
       109913874 mcm4; DNA replication licensing factor MCM4
       109912736 mcm5; LOW QUALITY PROTEIN: DNA replication licensing factor MCM5
       109921189 LOW QUALITY PROTEIN: DNA replication licensing factor MCM6-like
       109926938 LOW QUALITY PROTEIN: maternal DNA replication licensing factor mcm6-like
       109936786 mcm7; DNA replication licensing factor MCM7
K04503 CCND1; G1/S-specific cyclin-D1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04683 TFDP1; transcription factor Dp-1
K09392 TFDP2; transcription factor Dp-2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04377 MYC; Myc proto-oncogene protein
K04377 MYC; Myc proto-oncogene protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K06623 CDKN2D; cyclin-dependent kinase inhibitor 2D
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K09993 CDKN1C; cyclin-dependent kinase inhibitor 1C
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K03094 SKP1; S-phase kinase-associated protein 1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; RING-box protein 1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K02213 CDC6; cell division control protein 6
K06628 CDC45; cell division control protein 45
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K06629 ASK; activator of S phase kinase
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06634 CCNH; cyclin H
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K03348 APC1; anaphase-promoting complex subunit 1
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K06636 SMC1; structural maintenance of chromosome 1
K06636 SMC1; structural maintenance of chromosome 1
K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06670 SCC1; cohesin complex subunit SCC1
K06670 SCC1; cohesin complex subunit SCC1
K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04802 PCNA; proliferating cell nuclear antigen
K02603 ORC1; origin recognition complex subunit 1
K02604 ORC2; origin recognition complex subunit 2
K02605 ORC3; origin recognition complex subunit 3
K02606 ORC4; origin recognition complex subunit 4
K02607 ORC5; origin recognition complex subunit 5
K02608 ORC6; origin recognition complex subunit 6
K02540 MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:3.6.4.12]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:3.6.4.12]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
K02210 MCM7; DNA replication licensing factor MCM7 [EC:3.6.4.12]
     04111 Cell cycle - yeast
     04112 Cell cycle - Caulobacter
     04113 Meiosis - yeast
     04114 Oocyte meiosis [PATH:rtp04114]
     04210 Apoptosis [PATH:rtp04210]
     04214 Apoptosis - fly
     04215 Apoptosis - multiple species
     04216 Ferroptosis [PATH:rtp04216]
     04217 Necroptosis [PATH:rtp04217]
     04115 p53 signaling pathway [PATH:rtp04115]
       109934178 atm; LOW QUALITY PROTEIN: serine-protein kinase ATM
       109911275 chek2; serine/threonine-protein kinase Chk2
       109934427 atr; serine/threonine-protein kinase ATR
       109921452 chek1; serine/threonine-protein kinase Chk1
       109915034 gorab; RAB6-interacting golgin
       109934681 E3 ubiquitin-protein ligase Mdm2-like
       109921413 mdm4; protein Mdm4
       109923052 cdkn1b; cyclin-dependent kinase inhibitor 1B
       109919627 LOW QUALITY PROTEIN: G1/S-specific cyclin-D1-like
       109925537 G1/S-specific cyclin-D1-like
       109931888 G1/S-specific cyclin-D2-like
       109925336 cdk4; cyclin-dependent kinase 4
       109936365 cyclin-dependent kinase 6-like
       109920140 cyclin-dependent kinase 6-like
       109924247 ccne2; G1/S-specific cyclin-E2
       109932834 ccne1; G1/S-specific cyclin-E1 isoform X1
       109923466 cyclin-dependent kinase 2-like isoform X1
       109926412 cyclin-dependent kinase 2-like
       109931295 protein reprimo-like
       109935081 ccnb1; G2/mitotic-specific cyclin-B1
       109914894 ccnb2; G2/mitotic-specific cyclin-B2
       109911524 cdk1; cyclin-dependent kinase 1
       109911340 growth arrest and DNA damage-inducible protein GADD45 alpha-like
       109933624 gadd45g; growth arrest and DNA damage-inducible protein GADD45 gamma
       109926854 gadd45a; growth arrest and DNA damage-inducible protein GADD45 alpha
       109912678 LOW QUALITY PROTEIN: growth arrest and DNA damage-inducible protein GADD45 beta-like
       109937287 gtse1; LOW QUALITY PROTEIN: G2 and S phase-expressed protein 1
       109929457 tumor necrosis factor receptor superfamily member 6-like
       109912098 LOW QUALITY PROTEIN: p53-induced death domain-containing protein 1-like
       109911310 tumor necrosis factor receptor superfamily member 10A-like isoform X1
       109929740 caspase-8-like
       109915462 LOW QUALITY PROTEIN: caspase-8-like
       109932037 uncharacterized protein LOC109932037
       109918844 apoptosis regulator BAX-like
       109915959 siva1; apoptosis regulatory protein Siva
       109923202 LOW QUALITY PROTEIN: bcl-2-like protein 1
       109930204 apoptosis regulator Bcl-2-like
       109916500 ei24; etoposide-induced protein 2.4 homolog
       109911547 protein shisa-5-like isoform X1
       109925665 perp; p53 apoptosis effector related to PMP-22
       109925601 zmat3; zinc finger matrin-type protein 3
       109912553 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase SIAH1-like
       109910711 cytochrome c
       109932546 cytochrome c
       109932240 LOW QUALITY PROTEIN: apoptotic protease-activating factor 1-like
       109927787 casp9; caspase-9 isoform X1
       109921085 aifm2; apoptosis-inducing factor 2
       109914316 apoptosis-inducing factor 2-like
       109910480 igfbp3; insulin-like growth factor-binding protein 3
       109914145 igf1; insulin-like growth factor I
       109921922 LOW QUALITY PROTEIN: plasminogen activator inhibitor 1-like
       109918114 thbs1; thrombospondin-1
       109921474 ribonucleoside-diphosphate reductase subunit M2-like
       109915267 ribonucleoside-diphosphate reductase subunit M2-like
       109914342 LOW QUALITY PROTEIN: sestrin-3-like
       109915661 sesn1; sestrin-1 isoform X1
       109936061 sestrin-3-like
       109938487 sestrin-1-like isoform X1
       109913977 pten; LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
       109913050 tsc2; LOW QUALITY PROTEIN: tuberin
       109919944 steap3; metalloreductase STEAP3
       109921638 rfwd2; E3 ubiquitin-protein ligase RFWD2 isoform X1
       109918898 RING finger and CHY zinc finger domain-containing protein 1-like
       109913221 rchy1; RING finger and CHY zinc finger domain-containing protein 1
       109933099 ccng1; cyclin-G1
       109913131 ccng2; cyclin-G2
       109913101 ppm1d; protein phosphatase 1D
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K19748 GORAB; RAB6-interacting golgin
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K10128 RPRM; reprimo, TP53-dependent G2 arrest mediator candidate
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10129 GTSE1; G-2 and S-phase expressed protein 1
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02159 BAX; apoptosis regulator BAX
K22744 SIVA1; apoptosis regulatory protein Siva
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K10134 EI24; etoposide-induced 2.4 mRNA
K10135 SCOTIN; scotin
K10136 PERP; TP53 apoptosis effector
K10137 ZMAT3; zinc finger, matrin type 3
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K22745 AIFM2; apoptosis-inducing factor 2
K22745 AIFM2; apoptosis-inducing factor 2
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05459 IGF1; insulin-like growth factor 1
K03982 SERPINE1; plasminogen activator inhibitor 1
K16857 THBS1; thrombospondin 1
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K07207 TSC2; tuberous sclerosis 2
K10142 STEAP3; metalloreductase STEAP3 [EC:1.16.1.-]
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10145 CCNG1; cyclin G1
K10146 CCNG2; cyclin G2
K10147 PPM1D; protein phosphatase 1D [EC:3.1.3.16]
     04218 Cellular senescence [PATH:rtp04218]
       109936507 transforming growth factor beta-3-like
       109911779 tgfb2; transforming growth factor beta-2
       109921206 tgfb3; transforming growth factor beta-3
       109921531 TGF-beta receptor type-1-like
       109916891 LOW QUALITY PROTEIN: TGF-beta receptor type-2-like
       109926924 TGF-beta receptor type-2-like isoform X1
       109914262 mothers against decapentaplegic homolog 2 isoform X1
       109936169 smad3; mothers against decapentaplegic homolog 3
       109925336 cdk4; cyclin-dependent kinase 4
       109936365 cyclin-dependent kinase 6-like
       109920140 cyclin-dependent kinase 6-like
       109919627 LOW QUALITY PROTEIN: G1/S-specific cyclin-D1-like
       109925537 G1/S-specific cyclin-D1-like
       109931888 G1/S-specific cyclin-D2-like
       109937908 rb1; LOW QUALITY PROTEIN: retinoblastoma-associated protein
       109919372 rbl1; retinoblastoma-like protein 1
       109915431 rbl2; retinoblastoma-like protein 2 isoform X1
       109915257 e2f1; transcription factor E2F1
       109929351 transcription factor E2F2-like
       109923152 e2f3; transcription factor E2F3
       109917377 e2f5; transcription factor E2F5
       109918432 e2f4; transcription factor E2F4 isoform X1
       109915990 pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       109915713 pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
       109921900 LOW QUALITY PROTEIN: phosphatidylinositol 4
       109916739 LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit alpha-like
       109917303 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       109926926 foxo1; forkhead box protein O1 isoform X1
       109921049 forkhead box protein O6-like
       109928072 foxo3; forkhead box protein O3
       109923052 cdkn1b; cyclin-dependent kinase inhibitor 1B
       109923466 cyclin-dependent kinase 2-like isoform X1
       109926412 cyclin-dependent kinase 2-like
       109924247 ccne2; G1/S-specific cyclin-E2
       109932834 ccne1; G1/S-specific cyclin-E1 isoform X1
       109938595 H-2 class I histocompatibility antigen
       109910400 class I histocompatibility antigen
       109911286 class I histocompatibility antigen
       109911288 class I histocompatibility antigen
       109919518 LOW QUALITY PROTEIN: H-2 class I histocompatibility antigen
       109929266 class I histocompatibility antigen
       109916317 class I histocompatibility antigen
       109915363 DLA class I histocompatibility antigen
       109922012 class I histocompatibility antigen
       109919789 H-2 class I histocompatibility antigen
       109925809 class I histocompatibility antigen
       109923802 major histocompatibility complex class I-related gene protein-like
       109919429 major histocompatibility complex class I-related gene protein-like
       109929269 class I histocompatibility antigen
       109924683 major histocompatibility complex class I-related gene protein-like
       109919287 GTPase HRas-like
       109931543 kras; GTPase KRas isoform X1
       109917328 nras; GTPase NRas
       109919272 rras2; ras-related protein R-Ras2
       109920125 ras-related protein R-Ras2-like
       109932084 mras; ras-related protein M-Ras
       109915744 GTPase HRas
       109931632 RAC-beta serine/threonine-protein kinase
       109915958 RAC-alpha serine/threonine-protein kinase-like isoform X1
       109916533 RAC-gamma serine/threonine-protein kinase isoform X1
       109916041 tsc1; hamartin isoform X1
       109913050 tsc2; LOW QUALITY PROTEIN: tuberin
       109921290 rheb; GTP-binding protein Rheb
       109914403 serine/threonine-protein kinase mTOR
       109913977 pten; LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
       109912079 sirt1; LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-1
       109916715 cyclin-A2-like
       109923733 ccna1; cyclin-A1
       109920876 lin9; protein lin-9 homolog
       109925764 lin37; protein lin-37 homolog
       109921501 lin52; protein lin-52 homolog isoform X1
       109931783 protein lin-54 homolog
       109910822 lin54; protein lin-54 homolog
       109928621 histone-binding protein RBBP7
       109920441 histone-binding protein RBBP4 isoform X1
       109925114 foxm1; forkhead box protein M1
       109916636 myc proto-oncogene protein-like
       109923817 transcriptional regulator Myc-B-like
       109934681 E3 ubiquitin-protein ligase Mdm2-like
       109926781 rassf5; ras association domain-containing protein 5 isoform X1
       109915133 fbxw11; F-box/WD repeat-containing protein 11 isoform X1
       109920037 beta-TrCP
       109917037 homeodomain-interacting protein kinase 4-like
       109931770 homeodomain-interacting protein kinase 4-like
       109921333 homeodomain-interacting protein kinase 1-like isoform X1
       109911671 hipk3; homeodomain-interacting protein kinase 3 isoform X1
       109934948 homeodomain-interacting protein kinase 2-like
       109910556 ppp1cb; serine/threonine-protein phosphatase PP1-beta catalytic subunit
       109935119 ppp1cc; serine/threonine-protein phosphatase PP1-gamma catalytic subunit
       109911534 raf1; RAF proto-oncogene serine/threonine-protein kinase
       109922810 map2k1; dual specificity mitogen-activated protein kinase kinase 1
       109923051 dual specificity mitogen-activated protein kinase kinase 1-like
       109911767 map2k2; dual specificity mitogen-activated protein kinase kinase 2
       109918415 mitogen-activated protein kinase 1
       109935925 ets1; protein C-ets-1
       109922694 dual specificity mitogen-activated protein kinase kinase 3
       109935499 dual specificity mitogen-activated protein kinase kinase 6
       109936687 mitogen-activated protein kinase 11-like
       109927220 mapk12; mitogen-activated protein kinase 12
       109932340 mitogen-activated protein kinase 13-like
       109932351 mitogen-activated protein kinase 14 isoform X1
       109914201 LOW QUALITY PROTEIN: mitogen-activated protein kinase 14B-like
       109911340 growth arrest and DNA damage-inducible protein GADD45 alpha-like
       109933624 gadd45g; growth arrest and DNA damage-inducible protein GADD45 gamma
       109926854 gadd45a; growth arrest and DNA damage-inducible protein GADD45 alpha
       109912678 LOW QUALITY PROTEIN: growth arrest and DNA damage-inducible protein GADD45 beta-like
       109911524 cdk1; cyclin-dependent kinase 1
       109935081 ccnb1; G2/mitotic-specific cyclin-B1
       109914894 ccnb2; G2/mitotic-specific cyclin-B2
       109911281 ccnb3; G2/mitotic-specific cyclin-B3
       109922609 double-strand break repair protein MRE11-like
       109927708 rad50; DNA repair protein RAD50
       109911127 nbn; nibrin
       109934178 atm; LOW QUALITY PROTEIN: serine-protein kinase ATM
       109911275 chek2; serine/threonine-protein kinase Chk2
       109913845 rad9a; cell cycle checkpoint control protein RAD9A
       109932584 LOW QUALITY PROTEIN: cell cycle checkpoint protein RAD1-like
       109934870 cell cycle checkpoint protein RAD1-like
       109934871 LOW QUALITY PROTEIN: cell cycle checkpoint protein RAD1-like
       109933730 hus1; checkpoint protein HUS1
       109934427 atr; serine/threonine-protein kinase ATR
       109921452 chek1; serine/threonine-protein kinase Chk1
       109927682 sqstm1; sequestosome-1 isoform X1
       109936429 transcription factor GATA-4-like isoform X1
       109936155 uncharacterized protein LOC109936155
       109916525 adapter protein CIKS-like
       109918515 nfkb1; nuclear factor NF-kappa-B p105 subunit
       109925335 interleukin-6-like
       109925317 il6; interleukin-6 isoform X1
       109932570 interleukin-8-like isoform X1
       109932587 interleukin-8-like
       109932598 interleukin-8-like isoform X1
       109915679 interleukin-8-like
       109915680 interleukin-8-like
       109932532 permeability factor 2-like
       109932542 interleukin-8-like isoform X1
       109936586 interleukin-8-like
       109936587 interleukin-8-like
       109910480 igfbp3; insulin-like growth factor-binding protein 3
       109921922 LOW QUALITY PROTEIN: plasminogen activator inhibitor 1-like
       109917680 MAP kinase-activated protein kinase 3-like
       109918144 mapkapk2; MAP kinase-activated protein kinase 2
       109938847 LOW QUALITY PROTEIN: MAP kinase-activated protein kinase 2-like
       109916273 zfp36l1; mRNA decay activator protein ZFP36L1 isoform X1
       109937644 mRNA decay activator protein ZFP36L2-A-like
       109918134 zfp36l2; LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36L2
       109930589 cacna1d; voltage-dependent L-type calcium channel subunit alpha-1D
       109914855 trpv4; transient receptor potential cation channel subfamily V member 4
       109924110 transient receptor potential cation channel subfamily M member 7-like
       109915698 trpm7; transient receptor potential cation channel subfamily M member 7 isoform X1
       109920196 transient receptor potential cation channel subfamily M member 6-like
       109926169 LOW QUALITY PROTEIN: calpain-1 catalytic subunit-like
       109927474 calpain-2 catalytic subunit-like
       109924922 EF-hand calcium-binding domain-containing protein 7-like
       109911843 calml6; calmodulin-like protein 6
       109911975 calm2; calmodulin
       109919921 LOW QUALITY PROTEIN: calmodulin-alpha-like
       109912684 calml4; calmodulin-like protein 4
       109916628 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like
       109917904 serine/threonine-protein phosphatase 2B catalytic subunit beta isoform-like
       109928191 serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
       109934526 ppp3r1; calcineurin subunit B type 1 isoform X1
       109911161 nuclear factor of activated T-cells
       109928122 nfatc2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1
       109938900 nfatc3; nuclear factor of activated T-cells, cytoplasmic 3
       109918007 itpr2; inositol 1,4,5-trisphosphate receptor type 2
       109924065 ADP/ATP translocase 1
       109914009 ADP/ATP translocase 1-like
       109928789 slc25a31; ADP/ATP translocase 4
       109917841 ppid; peptidyl-prolyl cis-trans isomerase D
       109928316 vdac1; voltage-dependent anion-selective channel protein 1
       109935019 vdac2; voltage-dependent anion-selective channel protein 2
       109927500 voltage-dependent anion-selective channel protein 2-like
       109936848 mcu; calcium uniporter protein, mitochondrial
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K09408 FOXO3; forkhead box protein O3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07830 RRAS2; Ras-related protein R-Ras2
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K02833 HRAS; GTPase HRas
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K21773 LIN9; protein lin-9
K21774 LIN37; protein lin-37
K21775 LIN52; protein lin-52
K21776 LIN54; protein lin-54
K21776 LIN54; protein lin-54
K10752 RBBP4; histone-binding protein RBBP4
K10752 RBBP4; histone-binding protein RBBP4
K09406 FOXM; forkhead box protein M
K04377 MYC; Myc proto-oncogene protein
K04377 MYC; Myc proto-oncogene protein
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K08015 RASSF5; Ras association domain-containing protein 5
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1; C-ets-1
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K10903 HUS1; HUS1 checkpoint protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K14381 SQSTM1; sequestosome 1
K09183 GATA4; GATA-binding protein 4
K21124 TRAF3IP2; adaptor protein CIKS
K21124 TRAF3IP2; adaptor protein CIKS
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K05405 IL6; interleukin 6
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K03982 SERPINE1; plasminogen activator inhibitor 1
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K18753 ZFP36L; butyrate response factor
K18753 ZFP36L; butyrate response factor
K18753 ZFP36L; butyrate response factor
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15040 VDAC2; voltage-dependent anion channel protein 2
K20858 MCU; calcium uniporter protein, mitochondrial
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: December 1, 2020