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KO |
 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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 02020 Two-component system
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04010 MAPK signaling pathway [PATH:shr04010]
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04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
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04011 MAPK signaling pathway - yeast
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04012 ErbB signaling pathway [PATH:shr04012]
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04014 Ras signaling pathway [PATH:shr04014]
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100933169 EGF; pro-epidermal growth factor isoform X1
100928770 TGFA; protransforming growth factor alpha isoform X1
100929695 FGF1; fibroblast growth factor 1 isoform X1
100934542 FGF2; fibroblast growth factor 2
100923118 FGF18; fibroblast growth factor 18
100925286 FGF20; fibroblast growth factor 20
100928224 FGF5; fibroblast growth factor 5
100934722 FGF6; fibroblast growth factor 6
100921812 FGF4; fibroblast growth factor 4
100922075 FGF3; fibroblast growth factor 3
100925381 FGF8; fibroblast growth factor 8 isoform X3
100925383 FGF7; fibroblast growth factor 7
100932059 FGF17; fibroblast growth factor 17
100934743 FGF16; fibroblast growth factor 16
100915656 FGF22; fibroblast growth factor 22
100920456 FGF9; fibroblast growth factor 9
116423189 FGF10; fibroblast growth factor 10
100916676 FGF19; fibroblast growth factor 19
100931317 FGF21; fibroblast growth factor 21
100914586 FGF23; fibroblast growth factor 23
100930279 NGF; beta-nerve growth factor
100934810 BDNF; brain-derived neurotrophic factor isoform X2
100918745 NTF3; neurotrophin-3 isoform X1
100918816 IGF1; insulin-like growth factor I isoform X1
100928068 IGF2; insulin-like growth factor II
100924985 PDGFA; platelet-derived growth factor subunit A isoform X1
116422035 platelet-derived growth factor subunit A-like
100917875 PDGFB; platelet-derived growth factor subunit B isoform X2
100928148 PDGFC; platelet-derived growth factor C
100916102 PDGFD; platelet-derived growth factor D isoform X1
100930278 CSF1; macrophage colony-stimulating factor 1 isoform X2
100934452 KITLG; kit ligand isoform X1
100913507 FLT3LG; fms-related tyrosine kinase 3 ligand
100913423 VEGFA; vascular endothelial growth factor A
100922413 VEGFB; vascular endothelial growth factor B
100925473 PGF; placenta growth factor
100918372 VEGFD; vascular endothelial growth factor D
100928742 VEGFC; vascular endothelial growth factor C
100915696 HGF; hepatocyte growth factor isoform X1
100923925 ANGPT1; angiopoietin-1 isoform X1
100930153 ANGPT2; angiopoietin-2 isoform X1
100920602 ANGPT4; angiopoietin-4
100928870 EFNA2; ephrin-A2
100926716 EFNA5; ephrin-A5 isoform X1
100927939 EFNA1; ephrin-A1
116423339 EFNA3; LOW QUALITY PROTEIN: ephrin-A3
116423340 EFNA4; ephrin-A4 isoform X1
100914017 EGFR; epidermal growth factor receptor isoform X1
100914347 FGFR1; fibroblast growth factor receptor 1 isoform X1
100932215 FGFR2; fibroblast growth factor receptor 2 isoform X4
100913979 FGFR3; fibroblast growth factor receptor 3 isoform X1
100919819 FGFR4; fibroblast growth factor receptor 4
100931911 death domain-containing membrane protein NRADD
100927086 NGFR; tumor necrosis factor receptor superfamily member 16
100916388 NTRK1; high affinity nerve growth factor receptor
100927322 NTRK2; BDNF/NT-3 growth factors receptor isoform X1
100929204 INSR; insulin receptor isoform X1
100916673 IGF1R; insulin-like growth factor 1 receptor
100925116 PDGFRA; platelet-derived growth factor receptor alpha isoform X2
100917212 PDGFRB; platelet-derived growth factor receptor beta
100916950 CSF1R; macrophage colony-stimulating factor 1 receptor
100929346 KIT; mast/stem cell growth factor receptor Kit isoform X2
100929912 FLT3; receptor-type tyrosine-protein kinase FLT3 isoform X1
100930426 FLT1; vascular endothelial growth factor receptor 1
111721579 vascular endothelial growth factor receptor kdr-like
100932306 FLT4; vascular endothelial growth factor receptor 3
100929091 KDR; vascular endothelial growth factor receptor 2
100917007 MET; hepatocyte growth factor receptor
100926118 TEK; angiopoietin-1 receptor
100926384 EPHA2; LOW QUALITY PROTEIN: ephrin type-A receptor 2
100928380 GRB2; growth factor receptor-bound protein 2
100925463 GAB1; GRB2-associated-binding protein 1 isoform X1
100928367 GAB2; GRB2-associated-binding protein 2 isoform X1
100926921 SHC1; SHC-transforming protein 1 isoform X4
100917745 SHC2; SHC-transforming protein 2 isoform X1
100914800 SHC3; SHC-transforming protein 3 isoform X1
100927458 SHC4; SHC-transforming protein 4 isoform X1
100930062 PTPN11; tyrosine-protein phosphatase non-receptor type 11 isoform X1
100915682 LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 11
100931009 SOS1; son of sevenless homolog 1 isoform X2
100932999 SOS2; son of sevenless homolog 2 isoform X1
100923119 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
100919206 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X2
100923297 RASGRP1; RAS guanyl-releasing protein 1 isoform X1
100916150 RASGRP2; RAS guanyl-releasing protein 2
100913998 RASGRP3; ras guanyl-releasing protein 3 isoform X1
100916458 RASGRP4; RAS guanyl-releasing protein 4
100916187 tyrosine-protein kinase ZAP-70
105749549 LAT; LOW QUALITY PROTEIN: linker for activation of T-cells family member 1
100923811 HTR7; 5-hydroxytryptamine receptor 7
100930507 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
100917513 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
100914745 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
100932612 GNB4; guanine nucleotide-binding protein subunit beta-4
100931703 GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X1
116419987 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
100917856 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
100933735 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
100920700 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
100934873 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
116419978 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
100920799 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 isoform X2
100920266 GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14
100914479 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
100927581 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
100920537 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
100915783 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
100929360 cAMP-dependent protein kinase catalytic subunit alpha
100915481 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha
100934183 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X2
100913731 cAMP-dependent protein kinase catalytic subunit alpha-like
100920760 RASGRF1; ras-specific guanine nucleotide-releasing factor 1 isoform X1
100916434 RASGRF2; ras-specific guanine nucleotide-releasing factor 2 isoform X2
100922600 GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X3
100920008 GRIN2A; glutamate receptor ionotropic, NMDA 2A isoform X1
100926323 GRIN2B; glutamate receptor ionotropic, NMDA 2B
100929017 CALM1; calmodulin-1 isoform X2
100920429 CALM2; calmodulin-2
105750699 calmodulin-A
100935134 CALM3; calmodulin-3 isoform X1
100925046 CALML4; calmodulin-like protein 4
116419081 calmodulin
116423459 calmodulin-like
116423460 calmodulin-like
100929168 ras-like protein
116419913 HRAS; GTPase HRas
100915526 KRAS; GTPase KRas isoform X1
100927252 ras-related protein Rab-26-like
100929426 ras protein let-60-like
100928986 NRAS; GTPase NRas
100926472 MRAS; ras-related protein M-Ras
100925964 RRAS; LOW QUALITY PROTEIN: ras-related protein R-Ras
100935072 RRAS2; ras-related protein R-Ras2
100923881 NF1; neurofibromin isoform X1
100933624 RASA1; ras GTPase-activating protein 1 isoform X1
100935390 RASA2; ras GTPase-activating protein 2 isoform X1
100918630 RASA3; ras GTPase-activating protein 3 isoform X1
116423480 RASA4B; ras GTPase-activating protein 4B isoform X1
100917774 SYNGAP1; ras/Rap GTPase-activating protein SynGAP isoform X1
100927484 RASAL1; rasGAP-activating-like protein 1
100933484 RASAL2; ras GTPase-activating protein nGAP isoform X1
100928263 RASAL3; RAS protein activator like-3 isoform X2
100917052 RASSF1; ras association domain-containing protein 1 isoform X2
100917434 RASSF5; ras association domain-containing protein 5 isoform X2
100929626 STK4; serine/threonine-protein kinase 4 isoform X1
100920711 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1
100919657 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
100932383 RAC2; ras-related C3 botulinum toxin substrate 2
100924669 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1
100928883 PAK1; serine/threonine-protein kinase PAK 1
100926699 serine/threonine-protein kinase PAK 3 isoform X1
100919323 PAK4; LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 4
100932749 PAK5; serine/threonine-protein kinase PAK 5
100924604 PAK6; serine/threonine-protein kinase PAK 6
100921931 RHOA; transforming protein RhoA
100929811 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
100932099 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
105749979 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
100926892 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100924976 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2
100935230 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
100917987 AKT1; RAC-alpha serine/threonine-protein kinase
100913262 AKT3; RAC-gamma serine/threonine-protein kinase
100925440 AKT2; RAC-beta serine/threonine-protein kinase
100926701 IKBKG; NF-kappa-B essential modulator isoform X3
100913624 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
100928932 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
100917619 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
100932473 RELA; transcription factor p65
100923199 BAD; bcl2-associated agonist of cell death isoform X1
100915548 BCL2L1; bcl-2-like protein 1 isoform X1
100919776 FASLG; tumor necrosis factor ligand superfamily member 6 isoform X1
100915809 RALGAPA1; ral GTPase-activating protein subunit alpha-1 isoform X13
100921036 RALGAPA2; ral GTPase-activating protein subunit alpha-2 isoform X1
100925388 RALGAPB; ral GTPase-activating protein subunit beta isoform X1
100917637 RALGDS; ral guanine nucleotide dissociation stimulator isoform X1
100918735 RGL1; ral guanine nucleotide dissociation stimulator-like 1 isoform X2
100935053 RGL2; ral guanine nucleotide dissociation stimulator-like 2 isoform X2
100922286 RALA; ras-related protein Ral-A
100922803 RALB; ras-related protein Ral-B
100926651 PLD1; phospholipase D1 isoform X1
100914579 PLD2; phospholipase D2
100915740 EXOC2; exocyst complex component 2
100915362 TBK1; serine/threonine-protein kinase TBK1 isoform X1
100932316 REL; proto-oncogene c-Rel
100930815 MAPK8; mitogen-activated protein kinase 8 isoform X1
100928480 MAPK10; mitogen-activated protein kinase 10 isoform X1
100924267 MAPK9; mitogen-activated protein kinase 9 isoform X1
100930842 RALBP1; ralA-binding protein 1
100918370 CDC42; cell division control protein 42 homolog isoform X1
100934446 AFDN; afadin isoform X1
100929610 SHOC2; leucine-rich repeat protein SHOC-2
100935202 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2
100921899 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
100917396 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
100934330 MAPK3; mitogen-activated protein kinase 3
100913231 MAPK1; mitogen-activated protein kinase 1 isoform X1
100920035 PLA1A; phospholipase A1 member A
100931036 phospholipase A2 homolog otoconin-22-like
100930695 PLA2G2D; group IID secretory phospholipase A2
100930174 PLA2G2C; putative inactive group IIC secretory phospholipase A2
100913626 PLA2G12B; group XIIB secretory phospholipase A2-like protein isoform X1
100916182 PLA2G10; group 10 secretory phospholipase A2
100930955 phospholipase A2, membrane associated-like
100919048 PLA2G1B; phospholipase A2
100930429 PLA2G2F; group IIF secretory phospholipase A2
100931218 phospholipase A2, membrane associated-like
105749658 PLA2G3; group 3 secretory phospholipase A2
105749916 acidic phospholipase A2 PLA-1-like isoform X1
100930545 group XIIA secretory phospholipase A2 isoform X4
100926134 group IIE secretory phospholipase A2
100926652 phospholipase A2, membrane associated-like
100927268 PLA2G4A; cytosolic phospholipase A2 isoform X1
100913647 PLA2G4E; cytosolic phospholipase A2 epsilon
100927005 PLA2G4C; cytosolic phospholipase A2 gamma isoform X1
100914602 PLA2G4B; cytosolic phospholipase A2 beta
100917893 PLA2G4D; cytosolic phospholipase A2 delta
100918158 PLA2G4F; cytosolic phospholipase A2 zeta isoform X1
100916580 PLA2G6; 85/88 kDa calcium-independent phospholipase A2 isoform X1
100932477 phospholipase A and acyltransferase 3 isoform X2
100932220 uncharacterized protein LOC100932220
100914678 ELK1; ETS domain-containing protein Elk-1
100926740 ETS1; protein C-ets-1 isoform X2
100925162 ETS2; protein C-ets-2
100916877 BRAP; BRCA1-associated protein isoform X1
100927277 KSR1; kinase suppressor of Ras 1 isoform X1
100918007 KSR2; kinase suppressor of Ras 2 isoform X1
100930457 RAPGEF5; rap guanine nucleotide exchange factor 5 isoform X1
100935403 RAP1A; ras-related protein Rap-1A isoform X2
100920135 RAP1B; ras-related protein Rap-1b
100917022 LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
100913337 PRKCA; protein kinase C alpha type
100924022 PRKCB; protein kinase C beta type isoform X1
100935225 PRKCG; protein kinase C gamma type
100930047 ABL1; tyrosine-protein kinase ABL1 isoform X2
100934520 ABL2; tyrosine-protein kinase ABL2 isoform X2
100925458 RAB5A; ras-related protein Rab-5A
100920142 RAB5B; ras-related protein Rab-5B
100922389 RAB5C; ras-related protein Rab-5C
100933960 ARF6; ADP-ribosylation factor 6
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K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2; Eph receptor A2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K09593 GAB1; GRB2-associated-binding protein 1
K08091 GAB2; GRB2-associated-binding protein 2
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K04163 HTR7; 5-hydroxytryptamine receptor 7
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K12326 RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02833 HRAS; GTPase HRas
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K08052 NF1; neurofibromin 1
K04352 RASA1; Ras GTPase-activating protein 1
K08053 RASA2; Ras GTPase-activating protein 2
K12380 RASA3; Ras GTPase-activating protein 3
K17630 RASA4; Ras GTPase-activating protein 4
K17631 SYNGAP; Ras/Rap GTPase-activating protein SynGAP
K17632 RASAL1; RAS protein activator-like 1
K17633 RASAL2; RAS protein activator-like 2
K17634 RASAL3; RAS protein activator-like 3
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K25768 RALGAPA; Ral GTPase-activating protein subunit alpha
K25768 RALGAPA; Ral GTPase-activating protein subunit alpha
K25769 RALGAPB; Ral GTPase-activating protein subunit beta
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K17635 RGL1; ral guanine nucleotide dissociation stimulator-like 1
K17636 RGL2; ral guanine nucleotide dissociation stimulator-like 2
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K17637 EXOC2; exocyst complex component 2
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09254 REL; c-Rel proto-oncogene protein
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K05702 AF6; afadin
K19613 SHOC2; leucine-rich repeat protein SHOC2
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K13618 PLA1A; phosphatidylserine sn-1 acylhydrolase [EC:3.1.1.111]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K04375 ELK1; ETS domain-containing protein Elk-1
K02678 ETS1; C-ets-1
K21932 ETS2; C-ets-2
K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
K14958 KSR1; kinase suppressor of Ras 1
K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
K08019 RAPGEF5; Rap guanine nucleotide exchange factor 5
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K07941 ARF6; ADP-ribosylation factor 6
|
04015 Rap1 signaling pathway [PATH:shr04015]
|
04310 Wnt signaling pathway [PATH:shr04310]
|
04330 Notch signaling pathway [PATH:shr04330]
|
04340 Hedgehog signaling pathway [PATH:shr04340]
|
04341 Hedgehog signaling pathway - fly
|
04350 TGF-beta signaling pathway [PATH:shr04350]
|
04390 Hippo signaling pathway [PATH:shr04390]
|
100919112 CRB2; protein crumbs homolog 2
100914305 CRB1; protein crumbs homolog 1
100914747 PARD3; partitioning defective 3 homolog isoform X1
100927657 PARD6G; partitioning defective 6 homolog gamma isoform X1
100913302 PARD6A; partitioning defective 6 homolog alpha isoform X1
100917902 PARD6B; partitioning defective 6 homolog beta
116423715 LOW QUALITY PROTEIN: partitioning defective 6 homolog gamma-like
100916377 PRKCZ; protein kinase C zeta type isoform X1
100925605 PRKCI; protein kinase C iota type
100919857 PATJ; inaD-like protein isoform X1
100920505 MPP5; MAGUK p55 subfamily member 5
100923995 AMOT; angiomotin isoform X1
100932865 YAP1; transcriptional coactivator YAP1 isoform X4
100925176 WWTR1; WW domain-containing transcription regulator protein 1
100920258 CDH1; cadherin-1
100934392 WTIP; Wilms tumor protein 1-interacting protein
116421812 AJUBA; LIM domain-containing protein ajuba
100915840 NF2; merlin isoform X1
100917518 merlin-like isoform X1
100918162 WWC1; protein KIBRA
100934978 FRMD1; FERM domain-containing protein 1
100932161 FRMD6; FERM domain-containing protein 6
100913559 SAV1; protein salvador homolog 1 isoform X1
100933711 STK3; serine/threonine-protein kinase 3 isoform X1
100914925 RASSF6; ras association domain-containing protein 6
100917052 RASSF1; ras association domain-containing protein 1 isoform X2
100921980 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
100927043 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
100932648 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform-like
100922551 PPP2R1B; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1
100927161 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
100931978 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1
100935274 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1
100922930 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X1
100933266 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X3
100919146 LATS2; serine/threonine-protein kinase LATS2
100931242 LATS1; serine/threonine-protein kinase LATS1
100931518 MOB1B; MOB kinase activator 1B isoform X2
100917131 MOB1A; MOB kinase activator 1A
100930570 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit
100915116 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit
100920526 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform X1
100920563 TP53BP2; apoptosis-stimulating of p53 protein 2 isoform X1
100927347 LLGL2; LLGL scribble cell polarity complex component 2 isoform X1
100921321 LLGL1; lethal(2) giant larvae protein homolog 1 isoform X1
100919917 SCRIB; protein scribble homolog isoform X1
100924037 DLG1; disks large homolog 1 isoform X1
100922041 DLG2; disks large homolog 2 isoform X1
100930826 DLG3; disks large homolog 3 isoform X1
100930883 DLG4; disks large homolog 4 isoform X3
100923022 DLG5; disks large homolog 5 isoform X1
105750662 LOW QUALITY PROTEIN: casein kinase I-like
100915794 CSNK1E; casein kinase I isoform X1
100923383 FBXW11; F-box/WD repeat-containing protein 11 isoform X1
100925642 BTRC; F-box/WD repeat-containing protein 1A isoform X4
100918460 TP73; tumor protein p73
116423037 BBC3; LOW QUALITY PROTEIN: bcl-2-binding component 3
100923438 TEAD3; transcriptional enhancer factor TEF-5
100918817 TEAD4; transcriptional enhancer factor TEF-3 isoform X2
100923718 TEAD1; transcriptional enhancer factor TEF-1 isoform X5
100926574 CCN2; CCN family member 2
100922034 GLI2; zinc finger protein GLI2 isoform X1
100924075 AREG; amphiregulin
100934619 BIRC5; baculoviral IAP repeat-containing protein 5
100914403 AFP; alpha-fetoprotein
100925715 ITGB2; integrin beta-2
100929695 FGF1; fibroblast growth factor 1 isoform X1
100932607 TGFB1; LOW QUALITY PROTEIN: transforming growth factor beta-1 proprotein
100914910 TGFB2; transforming growth factor beta-2 proprotein
100929617 TGFB3; transforming growth factor beta-3 proprotein
100913844 TGFBR1; TGF-beta receptor type-1 isoform X1
100913352 TGFBR2; TGF-beta receptor type-2
100916171 SMAD7; mothers against decapentaplegic homolog 7 isoform X1
100914956 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
100923201 SMAD3; mothers against decapentaplegic homolog 3
100923569 SMAD4; mothers against decapentaplegic homolog 4
100922915 SERPINE1; plasminogen activator inhibitor 1
100935094 BMP2; bone morphogenetic protein 2
100916609 BMP4; bone morphogenetic protein 4
100932026 BMP5; bone morphogenetic protein 5
100929544 BMP6; bone morphogenetic protein 6
100914254 BMP7; bone morphogenetic protein 7
100916021 bone morphogenetic protein 8B
100930564 GDF5; growth/differentiation factor 5
100929797 GDF6; growth/differentiation factor 6
116421208 GDF7; growth/differentiation factor 7
100919390 AMH; muellerian-inhibiting factor
100928319 BMPR1A; bone morphogenetic protein receptor type-1A
100920492 BMPR1B; bone morphogenetic protein receptor type-1B isoform X1
100925781 BMPR2; bone morphogenetic protein receptor type-2 isoform X1
100921630 SMAD1; mothers against decapentaplegic homolog 1
116421719 ID1; DNA-binding protein inhibitor ID-1
100929699 ID2; DNA-binding protein inhibitor ID-2
100928059 WNT1; proto-oncogene Wnt-1
100918306 WNT2; protein Wnt-2 isoform X3
100918389 WNT2B; protein Wnt-2b
100914628 WNT3A; protein Wnt-3a
100935307 WNT3; proto-oncogene Wnt-3
100925510 WNT4; protein Wnt-4 isoform X1
100917926 WNT5A; protein Wnt-5a
100924415 WNT5B; protein Wnt-5b
100933826 WNT6; protein Wnt-6
100925362 WNT7B; protein Wnt-7b
100931119 WNT7A; protein Wnt-7a
100934290 WNT8B; protein Wnt-8b
100923381 WNT8A; protein Wnt-8a
100914365 WNT9A; protein Wnt-9a
100919162 WNT9B; LOW QUALITY PROTEIN: protein Wnt-9b
100917765 WNT10A; protein Wnt-10a
100932979 WNT10B; protein Wnt-10b isoform X2
100913767 WNT11; protein Wnt-11
100921973 WNT16; protein Wnt-16
100921540 FZD1; frizzled-1
100923425 FZD7; frizzled-7
100932536 FZD2; frizzled-2
100919821 FZD3; frizzled-3 isoform X1
100919498 FZD4; frizzled-4
100916636 FZD5; frizzled-5
111721152 FZD8; frizzled-8
100919476 FZD6; frizzled-6 isoform X1
100914963 FZD10; frizzled-10
100932600 DVL1; segment polarity protein dishevelled homolog DVL-1
100932119 DVL3; segment polarity protein dishevelled homolog DVL-3
100931932 DVL2; segment polarity protein dishevelled homolog DVL-2
100913480 YWHAZ; 14-3-3 protein zeta/delta
100929371 YWHAB; 14-3-3 protein beta/alpha
100926531 YWHAQ; 14-3-3 protein theta
100922737 YWHAE; 14-3-3 protein epsilon isoform X1
100932455 YWHAG; 14-3-3 protein gamma
100921764 YWHAH; 14-3-3 protein eta
100920192 GSK3B; glycogen synthase kinase-3 beta isoform X1
100930636 CTNNB1; catenin beta-1 isoform X1
100925931 APC2; adenomatous polyposis coli protein 2 isoform X1
100915224 APC; adenomatous polyposis coli protein isoform X1
100923576 AXIN1; axin-1 isoform X1
100933740 AXIN2; axin-2 isoform X1
100913385 NKD2; protein naked cuticle homolog 2 isoform X1
100929536 NKD1; protein naked cuticle homolog 1
100930141 TCF7; transcription factor 7 isoform X1
100922609 TCF7L1; transcription factor 7-like 1
100922675 TCF7L2; transcription factor 7-like 2 isoform X11
100934638 LEF1; lymphoid enhancer-binding factor 1 isoform X1
100921308 MYC; myc proto-oncogene protein
100917462 CCND1; G1/S-specific cyclin-D1
100915359 CCND2; G1/S-specific cyclin-D2
100921166 CCND3; G1/S-specific cyclin-D3 isoform X1
100918115 SOX2; transcription factor SOX-2
100913837 SNAI2; zinc finger protein SNAI2
100914028 baculoviral IAP repeat-containing protein 2 isoform X1
100933131 baculoviral IAP repeat-containing protein 3 isoform X1
100928302 ACTG1; actin, cytoplasmic 2
100923807 actin, cytoplasmic type 5
100919051 ACTB; actin, cytoplasmic 1
100916712 LOW QUALITY PROTEIN: actin, cytoplasmic 2
100930828 catenin alpha-1
100925228 CTNNA2; catenin alpha-2 isoform X1
100921282 CTNNA3; catenin alpha-3 isoform X1
|
K16681 CRB; protein crumbs
K16681 CRB; protein crumbs
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K06092 INADL; InaD-like protein
K06091 MPP5; MAGUK p55 subfamily member 5
K16819 AMOT; angiomotin
K16687 YAP1; transcriptional coactivator YAP1
K16820 WWTR1; WW domain-containing transcription regulator protein 1
K05689 CDH1; cadherin 1, type 1, E-cadherin
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16684 NF2; merlin
K16684 NF2; merlin
K16685 WWC1; protein KIBRA
K16821 FRMD1; FERM domain-containing protein 1
K16822 FRMD6; FERM domain-containing protein 6
K16686 SAV1; scaffold protein salvador
K04412 STK3; serine/threonine kinase 3
K09854 RASSF6; Ras association domain-containing protein 6
K09850 RASSF1; Ras association domain-containing protein 1
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K06685 MOB1; MOB kinase activator 1
K06685 MOB1; MOB kinase activator 1
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K16823 TP53BP2; apoptosis-stimulating of p53 protein 2
K06094 LLGL; lethal(2) giant larvae protein
K06094 LLGL; lethal(2) giant larvae protein
K16175 SCRIB; protein scribble
K12076 DLG1; disks large protein 1
K12075 DLG2; discs large protein 2
K21098 DLG3; discs large protein 3
K11828 DLG4; discs large protein 4
K24050 DLG5; discs large protein 5
K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K10148 TP73; tumor protein p73
K10132 BBC3; Bcl-2-binding component 3
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K06827 CTGF; connective tissue growth factor (insulin-like growth factor-binding protein 8)
K16798 GLI2; zinc finger protein GLI2
K09782 AREG; amphiregulin
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K16144 AFP; alpha-fetoprotein
K06464 ITGB2; integrin beta 2
K18496 FGF1; fibroblast growth factor 1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K19631 SMAD7; mothers against decapentaplegic homolog 7
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03982 SERPINE1; plasminogen activator inhibitor 1
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K04665 AMH; anti-mullerian hormone
K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04676 SMAD1; mothers against decapentaplegic homolog 1
K04680 ID1; DNA-binding protein inhibitor ID1
K17693 ID2; DNA-binding protein inhibitor ID2
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K03213 NKD; naked cuticle
K03213 NKD; naked cuticle
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K16796 SOX2; transcription factor SOX2 (SOX group B)
K05706 SNAI2; snail 2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
|
04391 Hippo signaling pathway - fly
|
04392 Hippo signaling pathway - multiple species [PATH:shr04392]
|
100932466 DCHS2; protocadherin-23
100918722 DCHS1; protocadherin-16
100932038 FAT4; protocadherin Fat 4 isoform X1
100915794 CSNK1E; casein kinase I isoform X1
100915840 NF2; merlin isoform X1
100917518 merlin-like isoform X1
100918162 WWC1; protein KIBRA
100934978 FRMD1; FERM domain-containing protein 1
100932161 FRMD6; FERM domain-containing protein 6
100917052 RASSF1; ras association domain-containing protein 1 isoform X2
100914925 RASSF6; ras association domain-containing protein 6
100933711 STK3; serine/threonine-protein kinase 3 isoform X1
100913559 SAV1; protein salvador homolog 1 isoform X1
100919146 LATS2; serine/threonine-protein kinase LATS2
100931242 LATS1; serine/threonine-protein kinase LATS1
100931518 MOB1B; MOB kinase activator 1B isoform X2
100917131 MOB1A; MOB kinase activator 1A
100934392 WTIP; Wilms tumor protein 1-interacting protein
116421812 AJUBA; LIM domain-containing protein ajuba
100932865 YAP1; transcriptional coactivator YAP1 isoform X4
100925176 WWTR1; WW domain-containing transcription regulator protein 1
100923438 TEAD3; transcriptional enhancer factor TEF-5
100918817 TEAD4; transcriptional enhancer factor TEF-3 isoform X2
100923718 TEAD1; transcriptional enhancer factor TEF-1 isoform X5
100920147 RASSF4; ras association domain-containing protein 4 isoform X1
100927126 RASSF2; ras association domain-containing protein 2
100928883 PAK1; serine/threonine-protein kinase PAK 1
|
K16507 DCHS1_2; protocadherin-16/23
K16507 DCHS1_2; protocadherin-16/23
K16669 FAT4; protocadherin Fat 4
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K16684 NF2; merlin
K16684 NF2; merlin
K16685 WWC1; protein KIBRA
K16821 FRMD1; FERM domain-containing protein 1
K16822 FRMD6; FERM domain-containing protein 6
K09850 RASSF1; Ras association domain-containing protein 1
K09854 RASSF6; Ras association domain-containing protein 6
K04412 STK3; serine/threonine kinase 3
K16686 SAV1; scaffold protein salvador
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K06685 MOB1; MOB kinase activator 1
K06685 MOB1; MOB kinase activator 1
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16687 YAP1; transcriptional coactivator YAP1
K16820 WWTR1; WW domain-containing transcription regulator protein 1
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09851 RASSF2_4; Ras association domain-containing protein 2/4
K09851 RASSF2_4; Ras association domain-containing protein 2/4
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
|
04370 VEGF signaling pathway [PATH:shr04370]
|
04371 Apelin signaling pathway [PATH:shr04371]
|
04630 JAK-STAT signaling pathway [PATH:shr04630]
|
04064 NF-kappa B signaling pathway [PATH:shr04064]
|
04668 TNF signaling pathway [PATH:shr04668]
|
04066 HIF-1 signaling pathway [PATH:shr04066]
|
04068 FoxO signaling pathway [PATH:shr04068]
|
04020 Calcium signaling pathway [PATH:shr04020]
|
04070 Phosphatidylinositol signaling system [PATH:shr04070]
|
04072 Phospholipase D signaling pathway [PATH:shr04072]
|
04071 Sphingolipid signaling pathway [PATH:shr04071]
|
04024 cAMP signaling pathway [PATH:shr04024]
|
04022 cGMP-PKG signaling pathway [PATH:shr04022]
|
04151 PI3K-Akt signaling pathway [PATH:shr04151]
|
04152 AMPK signaling pathway [PATH:shr04152]
|
04150 mTOR signaling pathway [PATH:shr04150]
|
04075 Plant hormone signal transduction
|
|
|
09133 Signaling molecules and interaction
|
|
|
09140 Cellular Processes
|
|
|
09150 Organismal Systems
|
|
|
09160 Human Diseases
|
|
|
09161 Cancer: overview
|
05200 Pathways in cancer [PATH:shr05200]
|
116420529 DCC; netrin receptor DCC
100922757 caspase-3-like
100922500 CASP3; caspase-3
100931481 CASP9; caspase-9
100921499 APPL1; DCC-interacting protein 13-alpha
100920258 CDH1; cadherin-1
100930636 CTNNB1; catenin beta-1 isoform X1
100930828 catenin alpha-1
100925228 CTNNA2; catenin alpha-2 isoform X1
100921282 CTNNA3; catenin alpha-3 isoform X1
100923576 AXIN1; axin-1 isoform X1
100933740 AXIN2; axin-2 isoform X1
100925931 APC2; adenomatous polyposis coli protein 2 isoform X1
100915224 APC; adenomatous polyposis coli protein isoform X1
100920192 GSK3B; glycogen synthase kinase-3 beta isoform X1
100930141 TCF7; transcription factor 7 isoform X1
100922609 TCF7L1; transcription factor 7-like 1
100922675 TCF7L2; transcription factor 7-like 2 isoform X11
100934638 LEF1; lymphoid enhancer-binding factor 1 isoform X1
100934619 BIRC5; baculoviral IAP repeat-containing protein 5
100921308 MYC; myc proto-oncogene protein
100917462 CCND1; G1/S-specific cyclin-D1
100928059 WNT1; proto-oncogene Wnt-1
100918306 WNT2; protein Wnt-2 isoform X3
100918389 WNT2B; protein Wnt-2b
100914628 WNT3A; protein Wnt-3a
100935307 WNT3; proto-oncogene Wnt-3
100925510 WNT4; protein Wnt-4 isoform X1
100917926 WNT5A; protein Wnt-5a
100924415 WNT5B; protein Wnt-5b
100933826 WNT6; protein Wnt-6
100925362 WNT7B; protein Wnt-7b
100931119 WNT7A; protein Wnt-7a
100934290 WNT8B; protein Wnt-8b
100923381 WNT8A; protein Wnt-8a
100914365 WNT9A; protein Wnt-9a
100919162 WNT9B; LOW QUALITY PROTEIN: protein Wnt-9b
100917765 WNT10A; protein Wnt-10a
100932979 WNT10B; protein Wnt-10b isoform X2
100913767 WNT11; protein Wnt-11
100921973 WNT16; protein Wnt-16
100921540 FZD1; frizzled-1
100923425 FZD7; frizzled-7
100932536 FZD2; frizzled-2
100919821 FZD3; frizzled-3 isoform X1
100919498 FZD4; frizzled-4
100916636 FZD5; frizzled-5
111721152 FZD8; frizzled-8
100919476 FZD6; frizzled-6 isoform X1
100914963 FZD10; frizzled-10
100930633 LRP6; low-density lipoprotein receptor-related protein 6
100916936 LRP5; low-density lipoprotein receptor-related protein 5
100932600 DVL1; segment polarity protein dishevelled homolog DVL-1
100932119 DVL3; segment polarity protein dishevelled homolog DVL-3
100931932 DVL2; segment polarity protein dishevelled homolog DVL-2
105749059 proto-oncogene FRAT1
100930993 GSK-3-binding protein FRAT2
100915186 F2; prothrombin
100932795 AGT; angiotensinogen isoform X2
100934757 F2R; proteinase-activated receptor 1
100915832 F2RL3; proteinase-activated receptor 4
100928953 LPAR1; lysophosphatidic acid receptor 1 isoform X1
100932534 lysophosphatidic acid receptor 1-A-like
100915220 LPAR2; lysophosphatidic acid receptor 2
100915601 LPAR3; lysophosphatidic acid receptor 3
100914083 LPAR4; lysophosphatidic acid receptor 4
100922143 LPAR5; lysophosphatidic acid receptor 5
105749898 LPAR6; lysophosphatidic acid receptor 6
100927259 AGTR1; type-1 angiotensin II receptor
100916443 GNA12; guanine nucleotide-binding protein subunit alpha-12
100932191 GNA13; guanine nucleotide-binding protein subunit alpha-13
100913854 ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1
100927520 ARHGEF11; rho guanine nucleotide exchange factor 11 isoform X1
105750075 ARHGEF1; LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 1
100924388 PLEKHG5; pleckstrin homology domain-containing family G member 5
100921931 RHOA; transforming protein RhoA
100916611 ROCK1; rho-associated protein kinase 1 isoform X1
100916865 ROCK2; rho-associated protein kinase 2 isoform X1
100918574 CXCL12; stromal cell-derived factor 1 isoform X2
100934336 CXCR4; C-X-C chemokine receptor type 4 isoform X1
100914706 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2
100928725 GNAI3; guanine nucleotide-binding protein G(i) subunit alpha
100916740 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X1
100921047 PTGER1; prostaglandin E2 receptor EP1 subtype
116423723 PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1
100931285 PTGER4; prostaglandin E2 receptor EP4 subtype
100930666 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
100922193 ADCY1; adenylate cyclase type 1
100922434 ADCY2; adenylate cyclase type 2
100925657 ADCY3; adenylate cyclase type 3
100920243 ADCY4; adenylate cyclase type 4 isoform X1
100932634 ADCY6; adenylate cyclase type 6 isoform X1
100929278 ADCY7; adenylate cyclase type 7 isoform X3
100923926 ADCY8; adenylate cyclase type 8 isoform X1
100926025 ADCY9; adenylate cyclase type 9 isoform X2
100929360 cAMP-dependent protein kinase catalytic subunit alpha
100915481 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha
100934183 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X2
100913731 cAMP-dependent protein kinase catalytic subunit alpha-like
100930507 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
100917513 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
100914745 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
100932612 GNB4; guanine nucleotide-binding protein subunit beta-4
100931703 GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X1
116419987 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
100917856 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
100933735 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
100920700 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
100934873 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
116419978 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
100920799 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 isoform X2
100920266 GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14
100914479 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
100927581 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
100920537 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
100915783 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
100917328 COL4A3; collagen alpha-3(IV) chain
100923249 COL4A2; collagen alpha-2(IV) chain
100923506 COL4A1; collagen alpha-1(IV) chain
100931618 COL4A5; collagen alpha-5(IV) chain
100917586 COL4A4; collagen alpha-4(IV) chain
100925578 LAMA1; laminin subunit alpha-1
100924495 LAMA2; laminin subunit alpha-2 isoform X4
100924531 LAMA5; laminin subunit alpha-5
100934145 LAMA3; laminin subunit alpha-3 isoform X1
100926054 LAMA4; laminin subunit alpha-4 isoform X1
100929086 LAMB1; laminin subunit beta-1
100931469 laminin subunit beta-2
111719421 laminin subunit beta-2-like
100922990 LAMB3; LOW QUALITY PROTEIN: laminin subunit beta-3
100930114 LAMB4; laminin subunit beta-4 isoform X1
100921255 LAMC1; laminin subunit gamma-1
100921523 LAMC2; laminin subunit gamma-2
100935179 LAMC3; laminin subunit gamma-3 isoform X1
100927509 FN1; fibronectin isoform X4
105749727 ITGA2; integrin alpha-2
100932021 ITGA2B; integrin alpha-IIb
100928379 ITGA3; integrin alpha-3 isoform X1
100929219 ITGA6; integrin alpha-6 isoform X1
100929053 ITGAV; integrin alpha-V
100913968 ITGB1; integrin beta-1 isoform X1
100933019 PTK2; focal adhesion kinase 1 isoform X6
100929811 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
100932099 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
105749979 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
100926892 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100924976 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2
100935230 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
100927199 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
100913737 NKX3-1; homeobox protein Nkx-3.1
100917987 AKT1; RAC-alpha serine/threonine-protein kinase
100913262 AKT3; RAC-gamma serine/threonine-protein kinase
100925440 AKT2; RAC-beta serine/threonine-protein kinase
100913624 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
100928932 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
100926701 IKBKG; NF-kappa-B essential modulator isoform X3
100919027 NFKBIA; LOW QUALITY PROTEIN: NF-kappa-B inhibitor alpha
100917619 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
100923463 NFKB2; nuclear factor NF-kappa-B p100 subunit
100932473 RELA; transcription factor p65
100926756 PTGS2; prostaglandin G/H synthase 2
100927789 NOS2; nitric oxide synthase, inducible
100934666 BCL2; apoptosis regulator Bcl-2
100914028 baculoviral IAP repeat-containing protein 2 isoform X1
100933131 baculoviral IAP repeat-containing protein 3 isoform X1
100928240 XIAP; E3 ubiquitin-protein ligase XIAP
100918596 BIRC7; LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 7
100915548 BCL2L1; bcl-2-like protein 1 isoform X1
100932053 TRAF1; TNF receptor-associated factor 1
100934749 TRAF2; TNF receptor-associated factor 2 isoform X1
100926344 TRAF3; TNF receptor-associated factor 3 isoform X1
100932711 TRAF4; TNF receptor-associated factor 4
100926831 TRAF5; TNF receptor-associated factor 5 isoform X2
100922331 TRAF6; TNF receptor-associated factor 6
100931480 MTOR; serine/threonine-protein kinase mTOR isoform X1
100935081 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
100930707 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X2
100923199 BAD; bcl2-associated agonist of cell death isoform X1
100928882 FOXO1; forkhead box protein O1
100919874 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
100920321 E3 ubiquitin-protein ligase Mdm2-like isoform X1
100922473 TP53; cellular tumor antigen p53 isoform X1
100928055 CDKN1B; cyclin-dependent kinase inhibitor 1B isoform X1
100926666 CDKN1A; cyclin-dependent kinase inhibitor 1
100920111 BCR; breakpoint cluster region protein
100930047 ABL1; tyrosine-protein kinase ABL1 isoform X2
100923581 CRKL; crk-like protein
116423462 CRK; adapter molecule crk isoform X1
100920890 CBL; E3 ubiquitin-protein ligase CBL
100920045 LOW QUALITY PROTEIN: signal transducer and activator of transcription 5A
100920307 STAT5B; signal transducer and activator of transcription 5B
100931060 PIM1; serine/threonine-protein kinase pim-1 isoform X1
100919108 PIM2; serine/threonine-protein kinase pim-2
100931404 KNG1; kininogen-1 isoform X1
100918955 EDN1; endothelin-1
100917896 BDKRB1; B1 bradykinin receptor
100918161 BDKRB2; B2 bradykinin receptor
100918230 EDNRA; endothelin-1 receptor
100931399 EDNRB; endothelin receptor type B
100916183 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha isoform X1
100920179 GNA11; guanine nucleotide-binding protein subunit alpha-11
100922938 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
100934049 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
100934311 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
100929015 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
100913337 PRKCA; protein kinase C alpha type
100924022 PRKCB; protein kinase C beta type isoform X1
100935225 PRKCG; protein kinase C gamma type
100935068 uncharacterized LOC100935068 precursor
100914681 IL4; interleukin-4
100934043 IL5; interleukin-5
105750762 IL6; interleukin-6
116420560 IL7; interleukin-7
100914201 IL12A; interleukin-12 subunit alpha
100932486 IL12B; interleukin-12 subunit beta
111720829 IL13; interleukin-13
100926512 IL15; interleukin-15 isoform X1
100933427 IL23A; interleukin-23 subunit alpha
100924490 EPO; erythropoietin
100914965 interferon tau-like
100920968 interferon tau-2-like
100914703 interferon tau-2-like
116420987 interferon omega-1-like
116420989 interferon omega-1-like
105750683 IFNG; interferon gamma
105750698 IL2RA; interleukin-2 receptor subunit alpha isoform X1
100913275 IL2RB; interleukin-2 receptor subunit beta
100929781 IL2RG; cytokine receptor common subunit gamma isoform X2
105749995 interleukin-3 receptor subunit alpha
100917948 IL3RA; interleukin-3 receptor subunit alpha isoform X1
100922104 IL4R; interleukin-4 receptor subunit alpha isoform X1
105750684 CSF2RB; cytokine receptor common subunit beta isoform X1
100916709 IL5RA; interleukin-5 receptor subunit alpha isoform X1
100924664 IL6R; interleukin-6 receptor subunit alpha
100913307 IL6ST; interleukin-6 receptor subunit beta isoform X1
100915478 IL7R; interleukin-7 receptor subunit alpha isoform X1
105749415 IL12RB1; LOW QUALITY PROTEIN: interleukin-12 receptor subunit beta-1
100931154 IL12RB2; interleukin-12 receptor subunit beta-2
100930920 IL13RA1; interleukin-13 receptor subunit alpha-1
105750697 IL15RA; interleukin-15 receptor subunit alpha
100930891 IL23R; interleukin-23 receptor
100922441 EPOR; erythropoietin receptor isoform X1
100919064 IFNAR1; LOW QUALITY PROTEIN: interferon alpha/beta receptor 1
105750087 IFNAR2; interferon alpha/beta receptor 2 isoform X1
111720994 IFNGR1; interferon gamma receptor 1
100929576 IFNGR2; interferon gamma receptor 2
100929628 EML4; echinoderm microtubule-associated protein-like 4 isoform X1
100931895 ALK; ALK tyrosine kinase receptor
100923297 RASGRP1; RAS guanyl-releasing protein 1 isoform X1
100916150 RASGRP2; RAS guanyl-releasing protein 2
100913998 RASGRP3; ras guanyl-releasing protein 3 isoform X1
100916458 RASGRP4; RAS guanyl-releasing protein 4
100916991 JAK1; tyrosine-protein kinase JAK1 isoform X1
100927237 JAK2; tyrosine-protein kinase JAK2 isoform X1
100920108 JAK3; tyrosine-protein kinase JAK3
100933581 STAT3; signal transducer and activator of transcription 3 isoform X1
105749862 STAT1; signal transducer and activator of transcription 1-alpha/beta
100933167 STAT2; signal transducer and activator of transcription 2 isoform X1
100933645 STAT4; signal transducer and activator of transcription 4
100930901 STAT6; signal transducer and activator of transcription 6 isoform X1
100913423 VEGFA; vascular endothelial growth factor A
100922413 VEGFB; vascular endothelial growth factor B
100925473 PGF; placenta growth factor
100918372 VEGFD; vascular endothelial growth factor D
100928742 VEGFC; vascular endothelial growth factor C
100928770 TGFA; protransforming growth factor alpha isoform X1
100933169 EGF; pro-epidermal growth factor isoform X1
100914017 EGFR; epidermal growth factor receptor isoform X1
100914727 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
100924985 PDGFA; platelet-derived growth factor subunit A isoform X1
116422035 platelet-derived growth factor subunit A-like
100917875 PDGFB; platelet-derived growth factor subunit B isoform X2
100925116 PDGFRA; platelet-derived growth factor receptor alpha isoform X2
100917212 PDGFRB; platelet-derived growth factor receptor beta
100918816 IGF1; insulin-like growth factor I isoform X1
100928068 IGF2; insulin-like growth factor II
100916673 IGF1R; insulin-like growth factor 1 receptor
100934452 KITLG; kit ligand isoform X1
100929346 KIT; mast/stem cell growth factor receptor Kit isoform X2
100913507 FLT3LG; fms-related tyrosine kinase 3 ligand
100929912 FLT3; receptor-type tyrosine-protein kinase FLT3 isoform X1
100915696 HGF; hepatocyte growth factor isoform X1
100917007 MET; hepatocyte growth factor receptor
100929695 FGF1; fibroblast growth factor 1 isoform X1
100934542 FGF2; fibroblast growth factor 2
100923118 FGF18; fibroblast growth factor 18
100925286 FGF20; fibroblast growth factor 20
100928224 FGF5; fibroblast growth factor 5
100934722 FGF6; fibroblast growth factor 6
100921812 FGF4; fibroblast growth factor 4
100922075 FGF3; fibroblast growth factor 3
100925381 FGF8; fibroblast growth factor 8 isoform X3
100925383 FGF7; fibroblast growth factor 7
100932059 FGF17; fibroblast growth factor 17
100934743 FGF16; fibroblast growth factor 16
100915656 FGF22; fibroblast growth factor 22
100920456 FGF9; fibroblast growth factor 9
116423189 FGF10; fibroblast growth factor 10
100916676 FGF19; fibroblast growth factor 19
100931317 FGF21; fibroblast growth factor 21
100914586 FGF23; fibroblast growth factor 23
100914347 FGFR1; fibroblast growth factor receptor 1 isoform X1
100932215 FGFR2; fibroblast growth factor receptor 2 isoform X4
100913979 FGFR3; fibroblast growth factor receptor 3 isoform X1
100919819 FGFR4; fibroblast growth factor receptor 4
100928380 GRB2; growth factor receptor-bound protein 2
100931009 SOS1; son of sevenless homolog 1 isoform X2
100932999 SOS2; son of sevenless homolog 2 isoform X1
100929168 ras-like protein
116419913 HRAS; GTPase HRas
100915526 KRAS; GTPase KRas isoform X1
100927252 ras-related protein Rab-26-like
100929426 ras protein let-60-like
100928986 NRAS; GTPase NRas
100913901 ARAF; serine/threonine-protein kinase A-Raf
100934801 BRAF; serine/threonine-protein kinase B-raf isoform X1
100935202 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2
100921899 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
100917396 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
100934330 MAPK3; mitogen-activated protein kinase 3
100913231 MAPK1; mitogen-activated protein kinase 1 isoform X1
116423739 JUN; transcription factor AP-1
100924435 FOS; proto-oncogene c-Fos
100926740 ETS1; protein C-ets-1 isoform X2
100915062 MMP1; interstitial collagenase
100935012 MMP2; 72 kDa type IV collagenase
100934566 MMP9; matrix metalloproteinase-9
100933600 CXCL8; interleukin-8
100932899 CDK4; cyclin-dependent kinase 4
100931885 RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1
100927200 RET; proto-oncogene tyrosine-protein kinase receptor Ret
100926427 CCDC6; LOW QUALITY PROTEIN: coiled-coil domain-containing protein 6
100918319 NCOA4; nuclear receptor coactivator 4
100916388 NTRK1; high affinity nerve growth factor receptor
100916994 TPM3; tropomyosin alpha-3 chain isoform X1
100926491 TPR; nucleoprotein TPR isoform X1
100916189 TFG; protein TFG isoform X1
100917052 RASSF1; ras association domain-containing protein 1 isoform X2
100917434 RASSF5; ras association domain-containing protein 5 isoform X2
100929626 STK4; serine/threonine-protein kinase 4 isoform X1
100916127 death-associated protein kinase 2 isoform X1
100933287 DAPK1; death-associated protein kinase 1
100934384 DAPK2; death-associated protein kinase 2 isoform X1
100914009 DAPK3; death-associated protein kinase 3
100923119 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
100919206 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X2
100914678 ELK1; ETS domain-containing protein Elk-1
100929017 CALM1; calmodulin-1 isoform X2
100920429 CALM2; calmodulin-2
105750699 calmodulin-A
100935134 CALM3; calmodulin-3 isoform X1
100925046 CALML4; calmodulin-like protein 4
116419081 calmodulin
116423459 calmodulin-like
116423460 calmodulin-like
100934917 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
100916233 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1
100913975 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1
100918427 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1
100917637 RALGDS; ral guanine nucleotide dissociation stimulator isoform X1
100922286 RALA; ras-related protein Ral-A
100922803 RALB; ras-related protein Ral-B
100930842 RALBP1; ralA-binding protein 1
100918370 CDC42; cell division control protein 42 homolog isoform X1
100919657 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
100932383 RAC2; ras-related C3 botulinum toxin substrate 2
100924669 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1
100926651 PLD1; phospholipase D1 isoform X1
100914579 PLD2; phospholipase D2
100930815 MAPK8; mitogen-activated protein kinase 8 isoform X1
100928480 MAPK10; mitogen-activated protein kinase 10 isoform X1
100924267 MAPK9; mitogen-activated protein kinase 9 isoform X1
100924183 PAX8; paired box protein Pax-8 isoform X1
100934154 PPARG; peroxisome proliferator-activated receptor gamma isoform X1
100926708 RXRA; retinoic acid receptor RXR-alpha isoform X3
100914649 RXRB; retinoic acid receptor RXR-beta isoform X2
100932014 RXRG; retinoic acid receptor RXR-gamma isoform X1
100928834 RARB; retinoic acid receptor beta isoform X1
100935401 ESR1; estrogen receptor isoform X1
100915121 ESR2; estrogen receptor beta
100924872 NCOA1; nuclear receptor coactivator 1 isoform X1
100923646 NCOA3; nuclear receptor coactivator 3 isoform X2
100930024 SP1; transcription factor Sp1 isoform X1
100920568 PPARD; peroxisome proliferator-activated receptor delta isoform X1
100923958 JUP; junction plakoglobin
100933393 ZBTB16; zinc finger and BTB domain-containing protein 16 isoform X1
100923612 RARA; retinoic acid receptor alpha isoform X1
100917627 CCNA2; cyclin-A2
100919936 CCNA1; cyclin-A1 isoform X1
100925902 PML; protein PML
100921236 RUNX1; runt-related transcription factor 1
100922016 RUNX1T1; protein CBFA2T1 isoform X1
100932651 SPI1; transcription factor PU.1 isoform X2
100933872 CEBPA; CCAAT/enhancer-binding protein alpha
105749994 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha
100928707 CSF3R; granulocyte colony-stimulating factor receptor
100916950 CSF1R; macrophage colony-stimulating factor 1 receptor
116421696 E2F1; transcription factor E2F1 isoform X1
100921594 E2F2; transcription factor E2F2
100934669 E2F3; transcription factor E2F3 isoform X1
100919026 MAX; protein max isoform X5
100928371 ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1
100924154 CDK6; cyclin-dependent kinase 6
100915359 CCND2; G1/S-specific cyclin-D2
100921166 CCND3; G1/S-specific cyclin-D3 isoform X1
100917592 CKS1B; cyclin-dependent kinases regulatory subunit 1
100915745 uncharacterized protein LOC100915745
100927300 SKP1; S-phase kinase-associated protein 1
100926417 CUL1; cullin-1
100918404 RBX1; E3 ubiquitin-protein ligase RBX1
100915218 SKP2; S-phase kinase-associated protein 2
100925631 CDK2; cyclin-dependent kinase 2 isoform X4
100920942 CCNE1; G1/S-specific cyclin-E1
100924454 CCNE2; G1/S-specific cyclin-E2 isoform X1
100914196 RB1; retinoblastoma-associated protein
100926902 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
100920439 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
116423727 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
100916731 BAK1; bcl-2 homologous antagonist/killer isoform X2
100916232 DDB2; DNA damage-binding protein 2
100923657 POLK; DNA polymerase kappa isoform X1
100914433 TERT; telomerase reverse transcriptase
100933029 MITF; microphthalmia-associated transcription factor isoform X5
100932607 TGFB1; LOW QUALITY PROTEIN: transforming growth factor beta-1 proprotein
100914910 TGFB2; transforming growth factor beta-2 proprotein
100929617 TGFB3; transforming growth factor beta-3 proprotein
100913844 TGFBR1; TGF-beta receptor type-1 isoform X1
100913352 TGFBR2; TGF-beta receptor type-2
100914956 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
100923201 SMAD3; mothers against decapentaplegic homolog 3
100923569 SMAD4; mothers against decapentaplegic homolog 4
100928711 MECOM; histone-lysine N-methyltransferase MECOM isoform X6
100915704 CTBP1; C-terminal-binding protein 1 isoform X3
116422006 CTBP2; C-terminal-binding protein 2
100913322 HDAC1; histone deacetylase 1
100927352 HDAC2; histone deacetylase 2
100931562 MLH1; DNA mismatch repair protein Mlh1
100928256 MSH2; DNA mismatch repair protein Msh2
100916871 MSH3; DNA mismatch repair protein Msh3 isoform X1
100919645 MSH6; DNA mismatch repair protein Msh6
100915673 BRCA2; breast cancer type 2 susceptibility protein
100931619 RAD51; DNA repair protein RAD51 homolog 1
100919776 FASLG; tumor necrosis factor ligand superfamily member 6 isoform X1
105749219 FAS; tumor necrosis factor receptor superfamily member 6
100925732 FADD; FAS-associated death domain protein
100931580 CASP8; caspase-8
100929676 BID; BH3-interacting domain death agonist
116423037 BBC3; LOW QUALITY PROTEIN: bcl-2-binding component 3
100932232 BCL2L11; LOW QUALITY PROTEIN: bcl-2-like protein 11
100919671 cytochrome c 2
111721251 cytochrome c
100932636 APAF1; apoptotic protease-activating factor 1 isoform X1
100927801 CASP7; caspase-7
100927230 KEAP1; kelch-like ECH-associated protein 1
100915496 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X2
100925365 HMOX1; heme oxygenase 1
100916256 NQO1; NAD(P)H dehydrogenase [quinone] 1
100928482 MGST2; microsomal glutathione S-transferase 2
100929215 GSTT2B; glutathione S-transferase theta-2B
100924507 MGST1; microsomal glutathione S-transferase 1
100926836 LOW QUALITY PROTEIN: glutathione S-transferase A4
100935165 GSTO1; glutathione S-transferase omega-1
100913363 glutathione S-transferase omega-1-like isoform X2
100927430 glutathione S-transferase Mu 2 isoform X2
100927692 glutathione S-transferase Mu 1-like
100927944 glutathione S-transferase Mu 3
100929408 MGST3; microsomal glutathione S-transferase 3
100926310 glutathione S-transferase-like
100926572 GSTA1; glutathione S-transferase A1
100927091 glutathione S-transferase
100917755 GSTP1; glutathione S-transferase P
100933898 TXNRD2; thioredoxin reductase 2, mitochondrial isoform X1
100921449 TXNRD1; thioredoxin reductase 1, cytoplasmic isoform X2
100922886 TXNRD3; thioredoxin reductase 3 isoform X2
111719447 VHL; von Hippel-Lindau disease tumor suppressor
100928425 ELOC; elongin-C
100915663 ELOB; elongin-B
100934724 CUL2; cullin-2
100913457 EGLN3; egl nine homolog 3
100929665 EGLN1; egl nine homolog 1
116422889 EGLN2; LOW QUALITY PROTEIN: egl nine homolog 2
100915344 FH; fumarate hydratase, mitochondrial isoform X1
100931887 HIF1A; hypoxia-inducible factor 1-alpha
100921392 EPAS1; endothelial PAS domain-containing protein 1
100917700 ARNT; aryl hydrocarbon receptor nuclear translocator isoform X1
100916593 ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X1
100921187 EP300; histone acetyltransferase p300 isoform X1
100926283 CREBBP; CREB-binding protein isoform X2
100915589 SLC2A1; solute carrier family 2, facilitated glucose transporter member 1
100931367 JAG1; protein jagged-1
100921475 JAG2; protein jagged-2 isoform X1
100919868 DLL1; delta-like protein 1
100933691 DLL4; delta-like protein 4 isoform X1
100928250 NOTCH1; neurogenic locus notch homolog protein 1
100919958 NOTCH2; neurogenic locus notch homolog protein 2
100926977 NOTCH3; neurogenic locus notch homolog protein 3
111720114 HES1; transcription factor HES-1
116422873 HES4; transcription factor HES-4
100933566 transcription factor HES-5
100933821 transcription factor HES-5-like
100916286 HEYL; hairy/enhancer-of-split related with YRPW motif-like protein
100922275 HEY1; hairy/enhancer-of-split related with YRPW motif protein 1
100918295 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2
100932306 FLT4; vascular endothelial growth factor receptor 3
100925029 SHH; sonic hedgehog protein
100934585 PTCH1; protein patched homolog 1 isoform X1
100935413 SMO; smoothened homolog
100930912 KIF7; kinesin-like protein KIF7
100922414 SUFU; suppressor of fused homolog isoform X2
100930638 GLI1; zinc finger protein GLI1 isoform X1
100922034 GLI2; zinc finger protein GLI2 isoform X1
100929554 GLI3; transcriptional activator GLI3
100935094 BMP2; bone morphogenetic protein 2
100916609 BMP4; bone morphogenetic protein 4
100922845 HHIP; hedgehog-interacting protein isoform X1
100916643 PTCH2; protein patched homolog 2 isoform X1
100933955 AR; androgen receptor
100928900 HSP90AB1; heat shock protein HSP 90-beta
100929957 HSP90AA1; heat shock protein HSP 90-alpha
100917881 HSP90B1; endoplasmin
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K06054 HES1; hairy and enhancer of split 1
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
|
05202 Transcriptional misregulation in cancer [PATH:shr05202]
|
05206 MicroRNAs in cancer [PATH:shr05206]
|
102464800 MIR19B; sha-miR-19b
100927199 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
102466506 MIR221; sha-miR-221
102464792 MIR222; sha-miR-222
100928055 CDKN1B; cyclin-dependent kinase inhibitor 1B isoform X1
102464803 MIR21; sha-miR-21
100928993 TIMP3; metalloproteinase inhibitor 3
102464790 MIRLET7G; sha-let-7g
102466098 MIRLET7A; sha-let-7a
102464809 MIRLET7I; sha-let-7i
100915526 KRAS; GTPase KRas isoform X1
100927252 ras-related protein Rab-26-like
100929426 ras protein let-60-like
100924154 CDK6; cyclin-dependent kinase 6
100924467 CDC25A; M-phase inducer phosphatase 1 isoform X1
100927310 CDC25B; M-phase inducer phosphatase 2 isoform X2
100924438 CDC25C; M-phase inducer phosphatase 3
116419660 HMGA2; high mobility group protein HMGI-C isoform X1
100917462 CCND1; G1/S-specific cyclin-D1
100915359 CCND2; G1/S-specific cyclin-D2
100920942 CCNE1; G1/S-specific cyclin-E1
100924454 CCNE2; G1/S-specific cyclin-E2 isoform X1
102464781 MIR126; sha-miR-126
100923581 CRKL; crk-like protein
116423462 CRK; adapter molecule crk isoform X1
100923523 HDAC4; histone deacetylase 4
100930442 HDAC5; histone deacetylase 5 isoform X1
100933553 FOXP1; forkhead box protein P1 isoform X5
100931060 PIM1; serine/threonine-protein kinase pim-1 isoform X1
100917007 MET; hepatocyte growth factor receptor
100926710 DNMT3A; DNA (cytosine-5)-methyltransferase 3A isoform X1
100935177 DNMT3B; DNA (cytosine-5)-methyltransferase 3B isoform X1
102465942 MIR133A; sha-miR-133a
100928648 MCL1; induced myeloid leukemia cell differentiation protein Mcl-1 isoform X1
111719772 bcl-2-like protein 2 isoform X2
100914017 EGFR; epidermal growth factor receptor isoform X1
100913423 VEGFA; vascular endothelial growth factor A
102466952 MIR200C; sha-miR-200c
100917269 ZEB1; zinc finger E-box-binding homeobox 1 isoform X3
102465943 MIR141; sha-miR-141
100914910 TGFB2; transforming growth factor beta-2 proprotein
100921438 EZR; ezrin
102464796 MIR125A; sha-miR-125a
100929867 PDCD4; programmed cell death protein 4 isoform X2
100921187 EP300; histone acetyltransferase p300 isoform X1
100926283 CREBBP; CREB-binding protein isoform X2
102464799 MIR30E; sha-miR-30e
102466508 MIR30C; sha-miR-30c
100928750 TPM1; tropomyosin alpha-1 chain isoform X6
100933652 SPRY2; protein sprouty homolog 2
100934666 BCL2; apoptosis regulator Bcl-2
100915477 SERPINB5; serpin B5
102466509 MIR205; sha-miR-205
100930600 ST14; suppressor of tumorigenicity 14 protein
100935353 cytochrome P450 1B1 isoform X2
102464795 MIR100; sha-miR-100
100931480 MTOR; serine/threonine-protein kinase mTOR isoform X1
100930970 RPTOR; regulatory-associated protein of mTOR isoform X1
100916072 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
100914727 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
100924586 receptor tyrosine-protein kinase erbB-3
100930047 ABL1; tyrosine-protein kinase ABL1 isoform X2
100934175 TP63; tumor protein 63 isoform X1
100917061 ZEB2; zinc finger E-box-binding homeobox 2 isoform X1
100922971 FSCN1; fascin
100917052 RASSF1; ras association domain-containing protein 1 isoform X2
102464794 MIR10B; sha-miR-10b
100914714 HOXD10; homeobox protein Hox-D10
105750469 LOW QUALITY PROTEIN: DNA damage-inducible transcript 4 protein
116421948 DDIT4; DNA damage-inducible transcript 4 protein
100924344 BMF; bcl-2-modifying factor
100919323 PAK4; LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 4
100934566 MMP9; matrix metalloproteinase-9
102464808 MIR25; sha-miR-25
102466100 MIR10A; sha-miR-10a
102464784 MIR23A; sha-miR-23a
102464786 MIR23B; sha-miR-23b
100931741 SLC7A1; high affinity cationic amino acid transporter 1
100914510 CCNG1; cyclin-G1
100925365 HMOX1; heme oxygenase 1
102464798 MIR150; sha-miR-150
100916106 STMN1; stathmin
100933581 STAT3; signal transducer and activator of transcription 3 isoform X1
100921308 MYC; myc proto-oncogene protein
100922757 caspase-3-like
100922500 CASP3; caspase-3
100929168 ras-like protein
116419913 HRAS; GTPase HRas
100928986 NRAS; GTPase NRas
102464813 MIR26A; sha-miR-26a
100934323 DNA (cytosine-5)-methyltransferase 1
100920187 DNA (cytosine-5)-methyltransferase 1
102464810 MIR135A; sha-miR-135a
100925931 APC2; adenomatous polyposis coli protein 2 isoform X1
100915224 APC; adenomatous polyposis coli protein isoform X1
100918116 IRS1; insulin receptor substrate 1
100926892 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100924976 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2
100935230 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
100917749 MAPK7; mitogen-activated protein kinase 7
100929811 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
100932099 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
105749979 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102466901 MIR200A; sha-miR-200a
102464797 MIR200B; sha-miR-200b
100924987 HNRNPK; heterogeneous nuclear ribonucleoprotein K isoform X1
100926369 RECK; reversion-inducing cysteine-rich protein with Kazal motifs
102464793 MIR128; sha-miR-128
100934669 E2F3; transcription factor E2F3 isoform X1
100924829 IRS2; insulin receptor substrate 2
100931354 IRS4; insulin receptor substrate 4
100928250 NOTCH1; neurogenic locus notch homolog protein 1
100919958 NOTCH2; neurogenic locus notch homolog protein 2
100926977 NOTCH3; neurogenic locus notch homolog protein 3
100928474 BMI1; polycomb complex protein BMI-1
100920437 MMP16; matrix metalloproteinase-16
102464775 MIR181A-2; sha-miR-181a-5p
102464802 MIR181A-1; sha-miR-181a-5p
100925167 ATM; serine-protein kinase ATM isoform X1
100917658 SOCS1; suppressor of cytokine signaling 1
105750824 suppressor of cytokine signaling 1
105750947 CD44; CD44 antigen isoform X1
100918678 DICER1; endoribonuclease Dicer
100919821 FZD3; frizzled-3 isoform X1
100923187 ITGA5; integrin alpha-5
100924383 RDX; radixin isoform X1
100921931 RHOA; transforming protein RhoA
100918318 PLAU; urokinase-type plasminogen activator
100916731 BAK1; bcl-2 homologous antagonist/killer isoform X2
100920784 ZFPM2; zinc finger protein ZFPM2 isoform X1
100920734 ITGB3; integrin beta-3
100934942 UBE2I; SUMO-conjugating enzyme UBC9
100934146 SOX4; transcription factor SOX-4
100930353 TNR; tenascin-R isoform X1
100925562 TNC; tenascin isoform X1
100930095 TNN; tenascin-N
100932708 TNXB; tenascin-X isoform X1
100917353 LOW QUALITY PROTEIN: ATP-dependent translocase ABCB1
100932550 LOW QUALITY PROTEIN: ATP-dependent translocase ABCB1
100932170 ABCC1; multidrug resistance-associated protein 1
100914310 BRCA1; breast cancer type 1 susceptibility protein isoform X1
100926666 CDKN1A; cyclin-dependent kinase inhibitor 1
100928870 EFNA2; ephrin-A2
100926716 EFNA5; ephrin-A5 isoform X1
100927939 EFNA1; ephrin-A1
116423339 EFNA3; LOW QUALITY PROTEIN: ephrin-A3
116423340 EFNA4; ephrin-A4 isoform X1
100926698 THBS1; thrombospondin-1
100916208 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1 isoform X1
100916223 TRIM71; E3 ubiquitin-protein ligase TRIM71
102466503 MIR9; sha-miR-9
100917619 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
102464783 MIR199A; sha-miR-199a
100928932 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
100926756 PTGS2; prostaglandin G/H synthase 2
100934330 MAPK3; mitogen-activated protein kinase 3
100913231 MAPK1; mitogen-activated protein kinase 1 isoform X1
100913337 PRKCA; protein kinase C alpha type
100924022 PRKCB; protein kinase C beta type isoform X1
100935225 PRKCG; protein kinase C gamma type
100928380 GRB2; growth factor receptor-bound protein 2
100913979 FGFR3; fibroblast growth factor receptor 3 isoform X1
100931885 RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1
100922473 TP53; cellular tumor antigen p53 isoform X1
100919874 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
100920321 E3 ubiquitin-protein ligase Mdm2-like isoform X1
100930617 MDM4; protein Mdm4 isoform X1
100925116 PDGFRA; platelet-derived growth factor receptor alpha isoform X2
100923119 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
100919206 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X2
102464801 MIR101; sha-miR-101
100935202 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2
100921899 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
100917396 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
100931009 SOS1; son of sevenless homolog 1 isoform X2
100932999 SOS2; son of sevenless homolog 2 isoform X1
100926921 SHC1; SHC-transforming protein 1 isoform X4
100924985 PDGFA; platelet-derived growth factor subunit A isoform X1
116422035 platelet-derived growth factor subunit A-like
102466512 MIR129; sha-miR-129
100927458 SHC4; SHC-transforming protein 4 isoform X1
100917875 PDGFB; platelet-derived growth factor subunit B isoform X2
100917212 PDGFRB; platelet-derived growth factor receptor beta
116421696 E2F1; transcription factor E2F1 isoform X1
100921594 E2F2; transcription factor E2F2
100932232 BCL2L11; LOW QUALITY PROTEIN: bcl-2-like protein 11
105750472 MARCKS; myristoylated alanine-rich C-kinase substrate
100925781 BMPR2; bone morphogenetic protein receptor type-2 isoform X1
100913322 HDAC1; histone deacetylase 1
100927352 HDAC2; histone deacetylase 2
100926678 EZH2; histone-lysine N-methyltransferase EZH2 isoform X2
100933392 GLS; glutaminase kidney isoform, mitochondrial isoform X1
100931861 GLS2; glutaminase liver isoform, mitochondrial isoform X1
100920847 SIRT1; NAD-dependent protein deacetylase sirtuin-1 isoform X1
100914628 WNT3A; protein Wnt-3a
100935307 WNT3; proto-oncogene Wnt-3
100929613 KIF23; kinesin-like protein KIF23 isoform X3
100916611 ROCK1; rho-associated protein kinase 1 isoform X1
100921656 PRKCE; protein kinase C epsilon type isoform X1
100915868 SLC45A3; solute carrier family 45 member 3
100932975 VIM; vimentin
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K23559 MIR19B; microRNA 19b
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K17010 MIR221; microRNA 221
K17011 MIR222; microRNA 222
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16863 MIR21; microRNA 21
K16866 TIMP3; metalloproteinase inhibitor 3
K16980 MIRLET7; microRNA let-7
K16980 MIRLET7; microRNA let-7
K16980 MIRLET7; microRNA let-7
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K09283 HMGA2; high mobility group AT-hook protein 2
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K16978 MIR126; microRNA 126
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K23582 FOXP1; forkhead box protein P1
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K16970 MIR133A; microRNA 133a
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K02163 BCLW; apoptosis regulator BCL-W
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K17017 MIR200C; microRNA 200c
K09299 ZEB1; zinc finger homeobox protein 1
K17018 MIR141; microRNA 141
K13376 TGFB2; transforming growth factor beta-2
K08007 EZR; ezrin
K16993 MIR125A; microRNA 125a
K16865 PDCD4; programmed cell death protein 4
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K17110 MIR30A_D_E; microRNA 30a/d/e
K17040 MIR30C; microRNA 30c
K10373 TPM1; tropomyosin 1
K17383 SPRY2; protein sprouty homolog 2
K02161 BCL2; apoptosis regulator Bcl-2
K10139 SERPINB5; serpin B5
K17150 MIR205; microRNA 205
K08670 ST14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K17041 MIR100; microRNA 100
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07436 CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.15.16]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K10149 TP63; tumor protein p63
K23560 ZEB2; zinc finger homeobox protein 2
K23551 FSCN1; fascin 1
K09850 RASSF1; Ras association domain-containing protein 1
K17393 MIR10B; microRNA 10b
K09295 HOXD10; homrobox protein Hox-D10
K08270 DDIT4; DNA-damage-inducible transcript 4
K08270 DDIT4; DNA-damage-inducible transcript 4
K17460 BMF; Bcl-2-modifying factor
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K17038 MIR25; microRNA 25
K16864 MIR10A; microRNA 10a
K17165 MIR23A; microRNA 23a
K17394 MIR23B; microRNA 23b
K13863 SLC7A1; solute carrier family 7 (cationic amino acid transporter), member 1
K10145 CCNG1; cyclin G1
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K17024 MIR150; microRNA 150
K04381 STMN1; stathmin 1
K04692 STAT3; signal transducer and activator of transcription 3
K04377 MYC; Myc proto-oncogene protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02833 HRAS; GTPase HRas
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K16984 MIR26A; microRNA 26a
K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K17144 MIR135; microRNA 135
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K17015 MIR200A; microRNA 200a
K17016 MIR200B; microRNA 200b
K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
K17461 RECK; reversion-inducing-cysteine-rich protein with kazal motifs
K17130 MIR128; microRNA 128
K06620 E2F3; transcription factor E2F3
K07187 IRS2; insulin receptor substrate 2
K07187 IRS2; insulin receptor substrate 2
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K11459 PCGF4; polycomb group RING finger protein 4
K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
K17025 MIR181A; microRNA 181a
K17025 MIR181A; microRNA 181a
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04694 SOCS1; suppressor of cytokine signaling 1
K04694 SOCS1; suppressor of cytokine signaling 1
K06256 CD44; CD44 antigen
K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
K02329 FZD3; frizzled 3
K06484 ITGA5; integrin alpha 5
K05762 RDX; radixin
K04513 RHOA; Ras homolog gene family, member A
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K14021 BAK; Bcl-2 homologous antagonist/killer
K17442 ZFPM2; zinc finger protein ZFPM2
K06493 ITGB3; integrin beta 3
K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
K23581 SOX4; transcription factor SOX4 (SOX group C)
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K16857 THBS1; thrombospondin 1
K17391 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
K16977 MIR9; microRNA 9
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K17118 MIR199A; microRNA 199a
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04364 GRB2; growth factor receptor-bound protein 2
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K17129 MIR101; microRNA 101
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K06279 SHC1; SHC-transforming protein 1
K04359 PDGFA; platelet-derived growth factor subunit A
K04359 PDGFA; platelet-derived growth factor subunit A
K17368 MIR129; microRNA 129
K17449 SHC4; SHC-transforming protein 4
K17386 PDGFB; platelet-derived growth factor subunit B
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K16341 BCL2L11; Bcl-2-like protein 11
K12561 MARCKS; myristoylated alanine-rich C-kinase substrate
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K01425 glsA; glutaminase [EC:3.5.1.2]
K01425 glsA; glutaminase [EC:3.5.1.2]
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K17387 KIF23; kinesin family member 23
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K15379 SLC45A3; solute carrier family 45, member 3
K07606 VIM; vimentin
|
05205 Proteoglycans in cancer [PATH:shr05205]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:shr05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:shr05207]
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:shr05208]
|
05203 Viral carcinogenesis [PATH:shr05203]
|
05230 Central carbon metabolism in cancer [PATH:shr05230]
|
05231 Choline metabolism in cancer [PATH:shr05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:shr05235]
|
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:shr05210]
|
05212 Pancreatic cancer [PATH:shr05212]
|
05225 Hepatocellular carcinoma [PATH:shr05225]
|
05226 Gastric cancer [PATH:shr05226]
|
05214 Glioma [PATH:shr05214]
|
05216 Thyroid cancer [PATH:shr05216]
|
05221 Acute myeloid leukemia [PATH:shr05221]
|
05220 Chronic myeloid leukemia [PATH:shr05220]
|
05217 Basal cell carcinoma [PATH:shr05217]
|
05218 Melanoma [PATH:shr05218]
|
05211 Renal cell carcinoma [PATH:shr05211]
|
05219 Bladder cancer [PATH:shr05219]
|
100913979 FGFR3; fibroblast growth factor receptor 3 isoform X1
100929168 ras-like protein
116419913 HRAS; GTPase HRas
100915526 KRAS; GTPase KRas isoform X1
100927252 ras-related protein Rab-26-like
100929426 ras protein let-60-like
100928986 NRAS; GTPase NRas
100913901 ARAF; serine/threonine-protein kinase A-Raf
100934801 BRAF; serine/threonine-protein kinase B-raf isoform X1
100935202 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2
100921899 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
100917396 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
100934330 MAPK3; mitogen-activated protein kinase 3
100913231 MAPK1; mitogen-activated protein kinase 1 isoform X1
100931885 RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1
100921308 MYC; myc proto-oncogene protein
100917052 RASSF1; ras association domain-containing protein 1 isoform X2
100916127 death-associated protein kinase 2 isoform X1
100933287 DAPK1; death-associated protein kinase 1
100934384 DAPK2; death-associated protein kinase 2 isoform X1
100914009 DAPK3; death-associated protein kinase 3
100919874 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
100920321 E3 ubiquitin-protein ligase Mdm2-like isoform X1
100922473 TP53; cellular tumor antigen p53 isoform X1
100926666 CDKN1A; cyclin-dependent kinase inhibitor 1
100917462 CCND1; G1/S-specific cyclin-D1
100932899 CDK4; cyclin-dependent kinase 4
100914196 RB1; retinoblastoma-associated protein
116421696 E2F1; transcription factor E2F1 isoform X1
100921594 E2F2; transcription factor E2F2
100934669 E2F3; transcription factor E2F3 isoform X1
100926698 THBS1; thrombospondin-1
100933188 HBEGF; proheparin-binding EGF-like growth factor
100935012 MMP2; 72 kDa type IV collagenase
100934566 MMP9; matrix metalloproteinase-9
100922486 UPK3A; uroplakin-3a
100926529 SRC; proto-oncogene tyrosine-protein kinase Src isoform X3
100933169 EGF; pro-epidermal growth factor isoform X1
100914727 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
100914017 EGFR; epidermal growth factor receptor isoform X1
100931155 TYMP; thymidine phosphorylase
100913423 VEGFA; vascular endothelial growth factor A
100915062 MMP1; interstitial collagenase
100933600 CXCL8; interleukin-8
100920258 CDH1; cadherin-1
|
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04377 MYC; Myc proto-oncogene protein
K09850 RASSF1; Ras association domain-containing protein 1
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K16857 THBS1; thrombospondin 1
K08523 HBEGF; heparin-binding EGF-like growth factor
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K19520 UPK3A; uroplakin-3a
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04357 EGF; epidermal growth factor
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K00758 deoA; thymidine phosphorylase [EC:2.4.2.4]
K05448 VEGFA; vascular endothelial growth factor A
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K10030 IL8; interleukin 8
K05689 CDH1; cadherin 1, type 1, E-cadherin
|
05215 Prostate cancer [PATH:shr05215]
|
05213 Endometrial cancer [PATH:shr05213]
|
05224 Breast cancer [PATH:shr05224]
|
05222 Small cell lung cancer [PATH:shr05222]
|
05223 Non-small cell lung cancer [PATH:shr05223]
|
100923843 FHIT; bis(5'-adenosyl)-triphosphatase
100928834 RARB; retinoic acid receptor beta isoform X1
100926708 RXRA; retinoic acid receptor RXR-alpha isoform X3
100914649 RXRB; retinoic acid receptor RXR-beta isoform X2
100932014 RXRG; retinoic acid receptor RXR-gamma isoform X1
100932899 CDK4; cyclin-dependent kinase 4
100924154 CDK6; cyclin-dependent kinase 6
100917462 CCND1; G1/S-specific cyclin-D1
100914196 RB1; retinoblastoma-associated protein
116421696 E2F1; transcription factor E2F1 isoform X1
100921594 E2F2; transcription factor E2F2
100934669 E2F3; transcription factor E2F3 isoform X1
100915526 KRAS; GTPase KRas isoform X1
100927252 ras-related protein Rab-26-like
100929426 ras protein let-60-like
100917052 RASSF1; ras association domain-containing protein 1 isoform X2
100917434 RASSF5; ras association domain-containing protein 5 isoform X2
100929626 STK4; serine/threonine-protein kinase 4 isoform X1
100929811 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
100932099 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
105749979 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
100926892 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100924976 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2
100935230 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
100917568 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X1
100917987 AKT1; RAC-alpha serine/threonine-protein kinase
100913262 AKT3; RAC-gamma serine/threonine-protein kinase
100925440 AKT2; RAC-beta serine/threonine-protein kinase
100923199 BAD; bcl2-associated agonist of cell death isoform X1
100931481 CASP9; caspase-9
100917083 FOXO3; forkhead box protein O3
100933169 EGF; pro-epidermal growth factor isoform X1
100928770 TGFA; protransforming growth factor alpha isoform X1
100914017 EGFR; epidermal growth factor receptor isoform X1
100914727 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
100915696 HGF; hepatocyte growth factor isoform X1
100917007 MET; hepatocyte growth factor receptor
100928380 GRB2; growth factor receptor-bound protein 2
100931009 SOS1; son of sevenless homolog 1 isoform X2
100932999 SOS2; son of sevenless homolog 2 isoform X1
100929168 ras-like protein
116419913 HRAS; GTPase HRas
100928986 NRAS; GTPase NRas
100913901 ARAF; serine/threonine-protein kinase A-Raf
100934801 BRAF; serine/threonine-protein kinase B-raf isoform X1
100935202 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2
100921899 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
100917396 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
100934330 MAPK3; mitogen-activated protein kinase 3
100913231 MAPK1; mitogen-activated protein kinase 1 isoform X1
100923119 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
100919206 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X2
100913337 PRKCA; protein kinase C alpha type
100924022 PRKCB; protein kinase C beta type isoform X1
100935225 PRKCG; protein kinase C gamma type
100922473 TP53; cellular tumor antigen p53 isoform X1
100926666 CDKN1A; cyclin-dependent kinase inhibitor 1
100926902 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
100920439 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
116423727 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
100916731 BAK1; bcl-2 homologous antagonist/killer isoform X2
100916232 DDB2; DNA damage-binding protein 2
100923657 POLK; DNA polymerase kappa isoform X1
100931867 KIF5A; kinesin heavy chain isoform X3
100916485 KIF5B; kinesin-1 heavy chain isoform X1
100921508 KIF5C; kinesin heavy chain isoform X1
100927200 RET; proto-oncogene tyrosine-protein kinase receptor Ret
100929628 EML4; echinoderm microtubule-associated protein-like 4 isoform X1
100931895 ALK; ALK tyrosine kinase receptor
100920108 JAK3; tyrosine-protein kinase JAK3
100933581 STAT3; signal transducer and activator of transcription 3 isoform X1
100920045 LOW QUALITY PROTEIN: signal transducer and activator of transcription 5A
100920307 STAT5B; signal transducer and activator of transcription 5B
|
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K08528 RARB; retinoic acid receptor beta
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K09408 FOXO3; forkhead box protein O3
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
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09172 Infectious disease: viral
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09171 Infectious disease: bacterial
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09174 Infectious disease: parasitic
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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09167 Endocrine and metabolic disease
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Sarcophilus harrisii (Tasmanian devil)