KEGG Orthology (KO) - Ursus maritimus (polar bear)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
   09121 Transcription
 
   09122 Translation
 
   09123 Folding, sorting and degradation
 
   09124 Replication and repair
     03030 DNA replication [PATH:umr03030]
     03410 Base excision repair [PATH:umr03410]
     03420 Nucleotide excision repair [PATH:umr03420]
     03430 Mismatch repair [PATH:umr03430]
       103669017 SSBP1; single stranded DNA binding protein 1
       103669972 PMS2; PMS1 homolog 2, mismatch repair system component
       103680847 MLH1; mutL homolog 1
       103671242 MSH6; mutS homolog 6
       103671767 MSH2; mutS homolog 2
       103681472 MSH3; mutS homolog 3
       103671057 MLH3; mutL homolog 3
       103672677 RFC1; replication factor C subunit 1
       103676051 RFC4; replication factor C subunit 4
       103670233 RFC2; replication factor C subunit 2
       103661224 RFC5; replication factor C subunit 5
       103664364 RFC3; replication factor C subunit 3
       103674409 PCNA; proliferating cell nuclear antigen
       103666634 EXO1; exonuclease 1
       103667158 RPA1; replication protein A1
       103666754 RPA2; replication protein A2
       103658764 RPA3; replication protein A3
       103673017 RPA4; replication protein A4
       103657272 POLD1; DNA polymerase delta 1, catalytic subunit
       103674686 POLD2; DNA polymerase delta 2, accessory subunit
       103678051 POLD3; DNA polymerase delta 3, accessory subunit
       103679511 POLD4; DNA polymerase delta 4, accessory subunit
       103657224 LIG1; DNA ligase 1
K03111 ssb; single-strand DNA-binding protein
K10858 PMS2; DNA mismatch repair protein PMS2
K08734 MLH1; DNA mismatch repair protein MLH1
K08737 MSH6; DNA mismatch repair protein MSH6
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08739 MLH3; DNA mismatch repair protein MLH3
K10754 RFC1; replication factor C subunit 1
K10755 RFC2_4; replication factor C subunit 2/4
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K10756 RFC3_5; replication factor C subunit 3/5
K04802 PCNA; proliferating cell nuclear antigen
K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
K07466 RFA1; replication factor A1
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K10741 RPA4; replication factor A4
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
     03440 Homologous recombination [PATH:umr03440]
     03450 Non-homologous end-joining [PATH:umr03450]
     03460 Fanconi anemia pathway [PATH:umr03460]
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
     05200 Pathways in cancer [PATH:umr05200]
       103665235 DCC; DCC netrin 1 receptor
       103680991 CASP3; caspase 3
       103666628 CASP9; caspase 9
       103675060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
       103673974 cadherin-1-like
       103673623 CDH1; cadherin 1
       103680384 CTNNB1; catenin beta 1
       103663779 CTNNA1; catenin alpha 1
       103667757 CTNNA3; catenin alpha 3
       103671441 CTNNA2; catenin alpha 2
       103668450 AXIN1; axin 1
       103665908 AXIN2; axin 2
       103675797 APC; APC, WNT signaling pathway regulator
       103678785 GSK3B; glycogen synthase kinase 3 beta
       103663815 TCF7; transcription factor 7 (T-cell specific, HMG-box)
       103671448 TCF7L1; transcription factor 7 like 1
       103657263 TCF7L2; transcription factor 7 like 2
       103661728 LEF1; lymphoid enhancer binding factor 1
       103665963 BIRC5; baculoviral IAP repeat containing 5
       103661697 MYC; v-myc avian myelocytomatosis viral oncogene homolog
       103671139 CCND1; cyclin D1
       103675620 WNT1; Wnt family member 1
       103675048 WNT2B; Wnt family member 2B
       103676588 WNT2; Wnt family member 2
       103678870 WNT3A; Wnt family member 3A
       103665889 WNT3; Wnt family member 3
       103666795 WNT4; Wnt family member 4
       103675062 WNT5A; Wnt family member 5A
       103675761 WNT5B; Wnt family member 5B
       103674134 WNT7B; Wnt family member 7B
       103669629 WNT7A; Wnt family member 7A
       103658927 WNT8B; Wnt family member 8B
       103663793 WNT8A; Wnt family member 8A
       103678871 WNT9A; Wnt family member 9A
       103665888 WNT9B; Wnt family member 9B
       103662888 WNT10A; Wnt family member 10A
       103675452 WNT10B; Wnt family member 10B
       103678127 WNT11; Wnt family member 11
       103676602 WNT16; Wnt family member 16
       103658791 FZD1; frizzled class receptor 1
       103659948 FZD7; frizzled class receptor 7
       103665868 FZD2; frizzled class receptor 2
       103675953 FZD3; frizzled class receptor 3
       103675375 FZD4; frizzled class receptor 4
       103659958 FZD5; frizzled class receptor 5
       103661527 FZD6; frizzled class receptor 6
       103661238 FZD10; frizzled class receptor 10
       103670220 FZD9; frizzled class receptor 9
       103677754 LRP6; LDL receptor related protein 6
       103679626 LRP5; LDL receptor related protein 5
       103660462 DVL2; dishevelled segment polarity protein 2
       103682075 segment polarity protein dishevelled homolog DVL-1-like
       103676184 DVL3; dishevelled segment polarity protein 3
       103672390 F2; coagulation factor II, thrombin
       103661870 AGT; angiotensinogen
       103663554 F2R; coagulation factor II thrombin receptor
       103678568 LPAR1; lysophosphatidic acid receptor 1
       103675138 LPAR2; lysophosphatidic acid receptor 2
       103662965 LPAR3; lysophosphatidic acid receptor 3
       103675824 LPAR4; lysophosphatidic acid receptor 4
       103677601 LPAR6; lysophosphatidic acid receptor 6
       103678133 AGTR1; angiotensin II receptor type 1
       103669942 GNA12; G protein subunit alpha 12
       103665670 GNA13; G protein subunit alpha 13
       103662491 ARHGEF12; Rho guanine nucleotide exchange factor 12
       103680778 rho guanine nucleotide exchange factor 11-like
       103668671 ARHGEF11; Rho guanine nucleotide exchange factor 11
       103680187 ARHGEF1; Rho guanine nucleotide exchange factor 1
       103666890 PLEKHG5; pleckstrin homology and RhoGEF domain containing G5
       103674825 RHOA; ras homolog family member A
       103662842 ROCK1; Rho associated coiled-coil containing protein kinase 1
       103660117 ROCK2; Rho associated coiled-coil containing protein kinase 2
       103667923 CXCL12; C-X-C motif chemokine ligand 12
       103667676 CXCR4; C-X-C motif chemokine receptor 4
       103658775 GNAI1; G protein subunit alpha i1
       103674803 GNAI2; G protein subunit alpha i2
       103675000 GNAI3; G protein subunit alpha i3
       103672874 PTGER2; prostaglandin E receptor 2
       103663132 PTGER3; prostaglandin E receptor 3
       103664680 PTGER4; prostaglandin E receptor 4
       103670935 guanine nucleotide-binding protein G(s) subunit alpha
       103670936 neuroendocrine secretory protein 55
       103679250 ADCY2; adenylate cyclase 2
       103671685 ADCY3; adenylate cyclase 3
       103679331 ADCY4; adenylate cyclase 4
       103678826 ADCY5; adenylate cyclase 5
       103675618 ADCY6; adenylate cyclase 6
       103673916 ADCY7; adenylate cyclase 7
       103661704 ADCY8; adenylate cyclase 8
       103668547 ADCY9; adenylate cyclase 9
       103662972 PRKACB; protein kinase cAMP-activated catalytic subunit beta
       103682183 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
       103682042 GNB1; G protein subunit beta 1
       103670041 GNB2; G protein subunit beta 2
       103656186 GNB3; G protein subunit beta 3
       103676121 GNB4; G protein subunit beta 4
       103676755 GNB5; G protein subunit beta 5
       103672837 GNG2; G protein subunit gamma 2
       103678196 GNG3; G protein subunit gamma 3
       103661898 GNG4; G protein subunit gamma 4
       103663109 GNG5; G protein subunit gamma 5
       103681653 GNG7; G protein subunit gamma 7
       103657071 GNG8; G protein subunit gamma 8
       103663361 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like
       103658734 GNG11; G protein subunit gamma 11
       103663028 GNG12; G protein subunit gamma 12
       103668461 GNG13; G protein subunit gamma 13
       103658731 GNGT1; G protein subunit gamma transducin 1
       103660550 GNGT2; G protein subunit gamma transducin 2
       103657624 COL4A2; collagen type IV alpha 2 chain
       103657625 COL4A1; collagen type IV alpha 1 chain
       103662858 COL4A3; collagen type IV alpha 3 chain
       103662859 COL4A4; collagen type IV alpha 4 chain
       103668926 COL4A5; collagen type IV alpha 5 chain
       103668927 COL4A6; collagen type IV alpha 6 chain
       103664656 LAMA1; laminin subunit alpha 1
       103663512 LAMA2; laminin subunit alpha 2
       103664853 LAMA3; laminin subunit alpha 3
       103660581 LAMA5; laminin subunit alpha 5
       103676980 LAMA4; laminin subunit alpha 4
       103674704 LAMB1; laminin subunit beta 1
       103675103 LAMB2; laminin subunit beta 2
       103672489 LAMB3; laminin subunit beta 3
       103674619 LAMB4; laminin subunit beta 4
       103672511 LAMC1; laminin subunit gamma 1
       103672510 LAMC2; laminin subunit gamma 2
       103670411 LAMC3; laminin subunit gamma 3
       103662788 FN1; fibronectin 1
       103664633 ITGA2; integrin subunit alpha 2
       103665592 ITGA2B; integrin subunit alpha 2b
       103660962 ITGA3; integrin subunit alpha 3
       103659892 ITGA6; integrin subunit alpha 6
       103659655 ITGAV; integrin subunit alpha V
       103656511 ITGB1; integrin subunit beta 1
       103670589 PTK2; protein tyrosine kinase 2
       103678592 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       103666874 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       103676125 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       103675162 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       103663617 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       103670766 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       103661921 PTEN; phosphatase and tensin homolog
       103666688 AKT3; AKT serine/threonine kinase 3
       103661038 AKT2; AKT serine/threonine kinase 2
       103676878 AKT1; AKT serine/threonine kinase 1
       103658916 CHUK; conserved helix-loop-helix ubiquitous kinase
       103677059 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       103679680 IKBKG; inhibitor of nuclear factor kappa B kinase subunit gamma
       103666055 NFKBIA; NFKB inhibitor alpha
       103677947 NFKB1; nuclear factor kappa B subunit 1
       103659023 NFKB2; nuclear factor kappa B subunit 2
       103679584 RELA; RELA proto-oncogene, NF-kB subunit
       103668648 PTGS2; prostaglandin-endoperoxide synthase 2
       103667420 NOS2; nitric oxide synthase 2
       103676164 BCL2; BCL2, apoptosis regulator
       103662462 BIRC2; baculoviral IAP repeat containing 2
       103662463 baculoviral IAP repeat-containing protein 3-like
       103680228 XIAP; X-linked inhibitor of apoptosis
       103660541 BIRC7; baculoviral IAP repeat containing 7
       103674345 BCL2L1; BCL2 like 1
       103670373 TRAF1; TNF receptor associated factor 1
       103675245 TRAF2; TNF receptor associated factor 2
       103656774 TRAF3; TNF receptor associated factor 3
       103667407 TRAF4; TNF receptor associated factor 4
       103672476 TRAF5; TNF receptor associated factor 5
       103659308 TRAF6; TNF receptor associated factor 6
       103666660 MTOR; mechanistic target of rapamycin
       103679516 RPS6KB2; ribosomal protein S6 kinase B2
       103667329 RPS6KB1; ribosomal protein S6 kinase B1
       103679423 BAD; BCL2 associated agonist of cell death
       103677704 FOXO1; forkhead box O1
       103656869 MDM2; MDM2 proto-oncogene
       103660368 TP53; tumor protein p53
       103677760 CDKN1B; cyclin dependent kinase inhibitor 1B
       103665536 CDKN1A; cyclin dependent kinase inhibitor 1A
       103669198 BCR; BCR, RhoGEF and GTPase activating protein
       103670413 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       103669230 CRKL; CRK like proto-oncogene, adaptor protein
       103667390 CRK; CRK proto-oncogene, adaptor protein
       103662312 CBL; Cbl proto-oncogene
       103672571 STAT5A; signal transducer and activator of transcription 5A
       103672570 STAT5B; signal transducer and activator of transcription 5B
       103665531 PIM1; Pim-1 proto-oncogene, serine/threonine kinase
       103668477 PIM2; Pim-2 proto-oncogene, serine/threonine kinase
       103676052 KNG1; kininogen 1
       103664910 EDN1; endothelin 1
       103673646 BDKRB1; bradykinin receptor B1
       103669660 BDKRB2; bradykinin receptor B2
       103658004 EDNRA; endothelin receptor type A
       103659180 endothelin B receptor-like
       103663281 GNAQ; G protein subunit alpha q
       103681813 GNA11; G protein subunit alpha 11
       103673552 PLCB2; phospholipase C beta 2
       103674425 PLCB1; phospholipase C beta 1
       103674426 PLCB4; phospholipase C beta 4
       103679549 PLCB3; phospholipase C beta 3
       103665907 PRKCA; protein kinase C alpha
       103668895 PRKCB; protein kinase C beta
       103672914 PRKCG; protein kinase C gamma
       103661804 IL2; interleukin 2
       103670504 IL3; interleukin 3
       103663832 IL4; interleukin 4
       103663836 IL5; interleukin 5
       103658871 IL6; interleukin 6
       103661362 IL7; interleukin 7
       103681335 IL12A; interleukin 12A
       103664531 IL12B; interleukin 12B
       103663833 IL13; interleukin 13
       103657977 IL15; interleukin 15
       103656219 IL23A; interleukin 23 subunit alpha
       103670120 EPO; erythropoietin
       103662147 interferon alpha-1/2-like
       103662148 interferon alpha-1/2-like
       103662149 interferon alpha-2-like
       103662193 interferon alpha-2-like
       103680385 interferon alpha-1/2-like
       103680386 interferon alpha-1/2-like
       103666985 interferon alpha-1/2-like
       103656858 IFNG; interferon gamma
       103676245 IL2RA; interleukin 2 receptor subunit alpha
       103676409 IL2RB; interleukin 2 receptor subunit beta
       103682591 IL2RG; interleukin 2 receptor subunit gamma
       103666330 IL3RA; interleukin 3 receptor subunit alpha
       103657902 IL4R; interleukin 4 receptor
       103676415 CSF2RB; colony stimulating factor 2 receptor beta common subunit
       103674266 IL5RA; interleukin 5 receptor subunit alpha
       103668717 IL6R; interleukin 6 receptor
       103663669 IL6ST; interleukin 6 signal transducer
       103664716 IL7R; interleukin 7 receptor
       103674947 IL12RB1; interleukin 12 receptor subunit beta 1
       103663034 IL12RB2; interleukin 12 receptor subunit beta 2
       103677732 IL13RA1; interleukin 13 receptor subunit alpha 1
       103676282 IL15RA; interleukin 15 receptor subunit alpha
       103663036 IL23R; interleukin 23 receptor
       103678709 EPOR; erythropoietin receptor
       103673220 IFNAR1; interferon alpha and beta receptor subunit 1
       103663370 IFNGR1; interferon gamma receptor 1
       103673221 IFNGR2; interferon gamma receptor 2
       103671544 EML4; echinoderm microtubule associated protein like 4
       103671905 ALK; anaplastic lymphoma receptor tyrosine kinase
       103673478 RASGRP1; RAS guanyl releasing protein 1
       103679557 RASGRP2; RAS guanyl releasing protein 2
       103671590 RASGRP3; RAS guanyl releasing protein 3
       103661068 RASGRP4; RAS guanyl releasing protein 4
       103663059 JAK1; Janus kinase 1
       103663212 JAK2; Janus kinase 2
       103675167 JAK3; Janus kinase 3
       103672573 STAT3; signal transducer and activator of transcription 3
       103659933 STAT1; signal transducer and activator of transcription 1
       103656206 STAT2; signal transducer and activator of transcription 2
       103659686 STAT4; signal transducer and activator of transcription 4
       103656427 STAT6; signal transducer and activator of transcription 6
       103664148 VEGFA; vascular endothelial growth factor A
       103679547 VEGFB; vascular endothelial growth factor B
       103671076 PGF; placental growth factor
       103679375 VEGFC; vascular endothelial growth factor C
       103668144 VEGFD; vascular endothelial growth factor D
       103671814 TGFA; transforming growth factor alpha
       103661742 EGF; epidermal growth factor
       103674660 EGFR; epidermal growth factor receptor
       103661560 ERBB2; erb-b2 receptor tyrosine kinase 2
       103670054 PDGFA; platelet derived growth factor subunit A
       103676520 PDGFB; platelet derived growth factor subunit B
       103672737 PDGFRA; platelet derived growth factor receptor alpha
       103664600 PDGFRB; platelet derived growth factor receptor beta
       103676495 IGF1; insulin like growth factor 1
       103671055 IGF2; insulin like growth factor 2
       103660044 insulin-like growth factor 1 receptor
       103660144 KITLG; KIT ligand
       103672804 KIT; KIT proto-oncogene receptor tyrosine kinase
       103657125 FLT3LG; fms related tyrosine kinase 3 ligand
       103664318 FLT3; fms related tyrosine kinase 3
       103658669 HGF; hepatocyte growth factor
       103676585 MET; MET proto-oncogene, receptor tyrosine kinase
       103663709 FGF1; fibroblast growth factor 1
       103661850 FGF2; fibroblast growth factor 2
       103664645 FGF10; fibroblast growth factor 10
       103664292 FGF9; fibroblast growth factor 9
       103681372 FGF20; fibroblast growth factor 20
       103673325 FGF17; fibroblast growth factor 17
       103675746 FGF6; fibroblast growth factor 6
       103675826 FGF16; fibroblast growth factor 16
       103676724 FGF7; fibroblast growth factor 7
       103665349 FGF5; fibroblast growth factor 5
       103671137 FGF3; fibroblast growth factor 3
       103664781 FGF18; fibroblast growth factor 18
       103658995 FGF8; fibroblast growth factor 8
       103671138 FGF19; fibroblast growth factor 19
       103657101 FGF21; fibroblast growth factor 21
       103675745 FGF23; fibroblast growth factor 23
       103659146 FGFR1; fibroblast growth factor receptor 1
       103657802 FGFR2; fibroblast growth factor receptor 2
       103664454 FGFR4; fibroblast growth factor receptor 4
       103665736 GRB2; growth factor receptor bound protein 2
       103671891 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       103665409 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       103669173 GTPase HRas-like
       103671035 HRAS; HRas proto-oncogene, GTPase
       103665244 KRAS; KRAS proto-oncogene, GTPase
       103669422 NRAS; neuroblastoma RAS viral oncogene homolog
       103669103 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       103669540 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       103679064 MAP2K1; mitogen-activated protein kinase kinase 1
       103681834 MAP2K2; mitogen-activated protein kinase kinase 2
       103669286 MAPK1; mitogen-activated protein kinase 1
       103657827 MAPK3; mitogen-activated protein kinase 3
       103670861 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       103671011 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       103660663 ETS1; ETS proto-oncogene 1, transcription factor
       103662453 MMP1; matrix metallopeptidase 1
       103662455 interstitial collagenase-like
       103673901 MMP2; matrix metallopeptidase 2
       103669705 MMP9; matrix metallopeptidase 9
       103665307 CXCL8; C-X-C motif chemokine ligand 8
       103656694 CDK4; cyclin dependent kinase 4
       103673837 RPS6KA5; ribosomal protein S6 kinase A5
       103668071 proto-oncogene tyrosine-protein kinase receptor Ret-like
       103667987 CCDC6; coiled-coil domain containing 6
       103667907 NCOA4; nuclear receptor coactivator 4
       103668407 TPM3; tropomyosin 3
       103668718 tropomyosin alpha-3 chain-like
       103669375 TPR; translocated promoter region, nuclear basket protein
       103673261 TFG; TRK-fused gene
       103674796 RASSF1; Ras association domain family member 1
       103671019 RASSF5; Ras association domain family member 5
       103669878 STK4; serine/threonine kinase 4
       103681831 DAPK3; death associated protein kinase 3
       103682208 DAPK1; death associated protein kinase 1
       103679099 DAPK2; death associated protein kinase 2
       103669754 PLCG1; phospholipase C gamma 1
       103662093 PLCG2; phospholipase C gamma 2
       103666919 ELK1; ELK1, ETS transcription factor
       103670304 CALM1; calmodulin 1
       103682041 CALML6; calmodulin like 6
       103676238 CALML5; calmodulin like 5
       103676239 CALML3; calmodulin like 3
       103671240 CALM2; calmodulin 2
       103679049 CALML4; calmodulin like 4
       103661761 CAMK2D; calcium/calmodulin dependent protein kinase II delta
       103664598 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       103668027 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       103674683 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       103670397 RALGDS; ral guanine nucleotide dissociation stimulator
       103674594 RALA; RAS like proto-oncogene A
       103658585 RALB; RAS like proto-oncogene B
       103662385 RALBP1; ralA binding protein 1
       103666578 CDC42; cell division cycle 42
       103670095 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
       103676407 RAC2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
       103666008 RAC3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
       103660447 PLD2; phospholipase D2
       103676145 PLD1; phospholipase D1
       103676947 MAPK10; mitogen-activated protein kinase 10
       103679990 MAPK9; mitogen-activated protein kinase 9
       103667893 MAPK8; mitogen-activated protein kinase 8
       103671861 PAX8; paired box 8
       103669544 PPARG; peroxisome proliferator activated receptor gamma
       103679944 RXRA; retinoid X receptor alpha
       103665560 RXRB; retinoid X receptor beta
       103658229 RXRG; retinoid X receptor gamma
       103681999 retinoic acid receptor beta-like
       103666963 ESR1; estrogen receptor 1
       103672317 ESR2; estrogen receptor 2
       103671686 NCOA1; nuclear receptor coactivator 1
       103669689 NCOA3; nuclear receptor coactivator 3
       103675530 SP1; Sp1 transcription factor
       103665463 PPARD; peroxisome proliferator activated receptor delta
       103672610 JUP; junction plakoglobin
       103662371 ZBTB16; zinc finger and BTB domain containing 16
       103662226 RARA; retinoic acid receptor alpha
       103661798 CCNA2; cyclin A2
       103664372 CCNA1; cyclin A1
       103679001 PML; promyelocytic leukemia
       103673224 RUNX1; runt related transcription factor 1
       103661423 RUNX1T1; RUNX1 translocation partner 1
       103672387 SPI1; Spi-1 proto-oncogene
       103666290 CSF2RA; colony stimulating factor 2 receptor alpha subunit
       103666329 granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like
       103666378 CSF3R; colony stimulating factor 3 receptor
       103664603 CSF1R; colony stimulating factor 1 receptor
       103674455 E2F1; E2F transcription factor 1
       103666789 E2F2; E2F transcription factor 2
       103678383 E2F3; E2F transcription factor 3
       103672194 MAX; MYC associated factor X
       103666838 ZBTB17; zinc finger and BTB domain containing 17
       103667098 ankyrin repeat domain-containing protein 34A-like
       103679831 cyclin-dependent kinase 4 inhibitor B-like
       103658796 CDK6; cyclin dependent kinase 6
       103675743 CCND2; cyclin D2
       103664092 CCND3; cyclin D3
       103663311 CKS2; CDC28 protein kinase regulatory subunit 2
       103664750 cyclin-dependent kinases regulatory subunit 2-like
       103668384 CKS1B; CDC28 protein kinase regulatory subunit 1B
       103663817 SKP1; S-phase kinase associated protein 1
       103668956 CUL1; cullin 1
       103674160 RBX1; ring-box 1
       103664708 SKP2; S-phase kinase associated protein 2
       103682503 CDK2; cyclin dependent kinase 2
       103661328 CCNE1; cyclin E1
       103661444 CCNE2; cyclin E2
       103677688 RB1; RB transcriptional corepressor 1
       103681651 GADD45B; growth arrest and DNA damage inducible beta
       103663135 GADD45A; growth arrest and DNA damage inducible alpha
       103657107 BAX; BCL2 associated X, apoptosis regulator
       103665481 putative Bcl-2 homologous antagonist/killer 2
       103672315 DDB2; damage specific DNA binding protein 2
       103663562 POLK; DNA polymerase kappa
       103679263 TERT; telomerase reverse transcriptase
       103674247 MITF; melanogenesis associated transcription factor
       103677394 transforming growth factor beta-1
       103658194 TGFB2; transforming growth factor beta 2
       103670922 TGFB3; transforming growth factor beta 3
       103678627 TGFBR1; transforming growth factor beta receptor 1
       103682015 TGFBR2; transforming growth factor beta receptor 2
       103663939 SMAD2; SMAD family member 2
       103664305 SMAD4; SMAD family member 4
       103680825 MECOM; MDS1 and EVI1 complex locus
       103659474 CTBP2; C-terminal binding protein 2
       103676926 CTBP1; C-terminal binding protein 1
       103676974 HDAC2; histone deacetylase 2
       103666443 HDAC1; histone deacetylase 1
       103680847 MLH1; mutL homolog 1
       103671767 MSH2; mutS homolog 2
       103681472 MSH3; mutS homolog 3
       103671242 MSH6; mutS homolog 6
       103664352 BRCA2; BRCA2, DNA repair associated
       103673456 RAD51; RAD51 recombinase
       103668115 FASLG; Fas ligand
       103661934 FAS; Fas cell surface death receptor
       103671072 FADD; Fas associated via death domain
       103659742 CASP8; caspase 8
       103675694 BID; BH3 interacting domain death agonist
       103657211 BBC3; BCL2 binding component 3
       103671504 BCL2L11; BCL2 like 11
       103658902 cytochrome c
       103660136 APAF1; apoptotic peptidase activating factor 1
       103657312 CASP7; caspase 7
       103678690 KEAP1; kelch like ECH associated protein 1
       103659605 NFE2L2; nuclear factor, erythroid 2 like 2
       103676557 HMOX1; heme oxygenase 1
       103673610 NQO1; NAD(P)H quinone dehydrogenase 1
       103658225 MGST3; microsomal glutathione S-transferase 3
       103657965 MGST2; microsomal glutathione S-transferase 2
       103663998 GSTA4; glutathione S-transferase alpha 4
       103663999 glutathione S-transferase A2-like
       103664000 glutathione S-transferase A4-like
       103664001 glutathione S-transferase A1
       103664002 glutathione S-transferase-like
       103675003 glutathione S-transferase Mu 1
       103675005 glutathione S-transferase Mu 1
       103675006 GSTM3; glutathione S-transferase mu 3
       103677796 MGST1; microsomal glutathione S-transferase 1
       103656766 GSTO1; glutathione S-transferase omega 1
       103656834 GSTO2; glutathione S-transferase omega 2
       103669208 glutathione S-transferase theta-1-like
       103669209 glutathione S-transferase theta-1
       103669212 glutathione S-transferase theta-2B-like
       103669279 glutathione S-transferase theta-1-like
       103669210 glutathione S-transferase theta-4-like
       103679616 glutathione S-transferase P-like
       103679521 glutathione S-transferase P-like
       103672175 uncharacterized LOC103672175
       103676482 TXNRD1; thioredoxin reductase 1
       103669473 TXNRD3; thioredoxin reductase 3
       103669257 TXNRD2; thioredoxin reductase 2
       103669642 VHL; von Hippel-Lindau tumor suppressor
       103681263 ELOC; elongin C
       103657431 transcription elongation factor B polypeptide 2-like
       103668800 ELOB; elongin B
       103656516 CUL2; cullin 2
       103661051 EGLN2; egl-9 family hypoxia inducible factor 2
       103661877 EGLN1; egl-9 family hypoxia inducible factor 1
       103680905 EGLN3; egl-9 family hypoxia inducible factor 3
       103666582 FH; fumarate hydratase
       103672464 HIF1A; hypoxia inducible factor 1 alpha subunit
       103671227 EPAS1; endothelial PAS domain protein 1
       103667537 ARNT; aryl hydrocarbon receptor nuclear translocator
       103660293 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       103668810 CREBBP; CREB binding protein
       103674159 EP300; E1A binding protein p300
       103670822 SLC2A1; solute carrier family 2 member 1
       103674543 JAG1; jagged 1
       103661087 DLL3; delta like canonical Notch ligand 3
       103660784 DLL1; delta like canonical Notch ligand 1
       103673543 DLL4; delta like canonical Notch ligand 4
       103675283 NOTCH1; notch 1
       103677132 NOTCH2; notch 2
       103677204 NOTCH3; notch 3
       103682271 NOTCH4; notch 4
       103676171 HES1; hes family bHLH transcription factor 1
       103661365 HEY1; hes related family bHLH transcription factor with YRPW motif 1
       103663519 HEY2; hes related family bHLH transcription factor with YRPW motif 2
       103666348 HEYL; hes related family bHLH transcription factor with YRPW motif-like
       103680018 FLT4; fms related tyrosine kinase 4
       103660977 SHH; sonic hedgehog
       103682234 PTCH1; patched 1
       103676698 SMO; smoothened, frizzled class receptor
       103660257 KIF7; kinesin family member 7
       103659044 SUFU; SUFU negative regulator of hedgehog signaling
       103656579 GLI1; GLI family zinc finger 1
       103658624 GLI2; GLI family zinc finger 2
       103674694 GLI3; GLI family zinc finger 3
       103674423 BMP2; bone morphogenetic protein 2
       103672975 BMP4; bone morphogenetic protein 4
       103657987 HHIP; hedgehog interacting protein
       103670897 PTCH2; patched 2
       103681153 AR; androgen receptor
       103664050 HSP90AB1; heat shock protein 90 alpha family class B member 1
       103656761 HSP90AA1; heat shock protein 90 alpha family class A member 1
       103676491 HSP90B1; heat shock protein 90 beta family member 1
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K03914 F2R; coagulation factor II (thrombin) receptor
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA. CD125; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K09290 TPM3; tropomyosin 3
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; probable transcription factor PML
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein
K04496 CTBP; C-terminal binding protein
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
     05202 Transcriptional misregulation in cancer [PATH:umr05202]
     05206 MicroRNAs in cancer [PATH:umr05206]
     05205 Proteoglycans in cancer [PATH:umr05205]
     05204 Chemical carcinogenesis [PATH:umr05204]
     05203 Viral carcinogenesis [PATH:umr05203]
     05230 Central carbon metabolism in cancer [PATH:umr05230]
     05231 Choline metabolism in cancer [PATH:umr05231]
     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:umr05235]
 
   09162 Cancer: specific types
     05210 Colorectal cancer [PATH:umr05210]
       103678785 GSK3B; glycogen synthase kinase 3 beta
       103668450 AXIN1; axin 1
       103665908 AXIN2; axin 2
       103680384 CTNNB1; catenin beta 1
       103675797 APC; APC, WNT signaling pathway regulator
       103663815 TCF7; transcription factor 7 (T-cell specific, HMG-box)
       103671448 TCF7L1; transcription factor 7 like 1
       103657263 TCF7L2; transcription factor 7 like 2
       103661728 LEF1; lymphoid enhancer binding factor 1
       103665963 BIRC5; baculoviral IAP repeat containing 5
       103661697 MYC; v-myc avian myelocytomatosis viral oncogene homolog
       103671139 CCND1; cyclin D1
       103665244 KRAS; KRAS proto-oncogene, GTPase
       103678592 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       103666874 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       103676125 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       103675162 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       103663617 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       103670766 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       103666688 AKT3; AKT serine/threonine kinase 3
       103661038 AKT2; AKT serine/threonine kinase 2
       103676878 AKT1; AKT serine/threonine kinase 1
       103679423 BAD; BCL2 associated agonist of cell death
       103666628 CASP9; caspase 9
       103669103 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       103669540 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       103679064 MAP2K1; mitogen-activated protein kinase kinase 1
       103681834 MAP2K2; mitogen-activated protein kinase kinase 2
       103669286 MAPK1; mitogen-activated protein kinase 1
       103657827 MAPK3; mitogen-activated protein kinase 3
       103670861 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       103671011 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       103670397 RALGDS; ral guanine nucleotide dissociation stimulator
       103674594 RALA; RAS like proto-oncogene A
       103658585 RALB; RAS like proto-oncogene B
       103670095 RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
       103676407 RAC2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
       103666008 RAC3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
       103674825 RHOA; ras homolog family member A
       103676947 MAPK10; mitogen-activated protein kinase 10
       103679990 MAPK9; mitogen-activated protein kinase 9
       103667893 MAPK8; mitogen-activated protein kinase 8
       103665235 DCC; DCC netrin 1 receptor
       103680991 CASP3; caspase 3
       103675060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
       103677394 transforming growth factor beta-1
       103658194 TGFB2; transforming growth factor beta 2
       103670922 TGFB3; transforming growth factor beta 3
       103678627 TGFBR1; transforming growth factor beta receptor 1
       103682015 TGFBR2; transforming growth factor beta receptor 2
       103663939 SMAD2; SMAD family member 2
       103664305 SMAD4; SMAD family member 4
       103680847 MLH1; mutL homolog 1
       103671767 MSH2; mutS homolog 2
       103681472 MSH3; mutS homolog 3
       103671242 MSH6; mutS homolog 6
       103657107 BAX; BCL2 associated X, apoptosis regulator
       103671504 BCL2L11; BCL2 like 11
       103657211 BBC3; BCL2 binding component 3
       103676164 BCL2; BCL2, apoptosis regulator
       103658902 cytochrome c
       103660368 TP53; tumor protein p53
       103665536 CDKN1A; cyclin dependent kinase inhibitor 1A
       103681651 GADD45B; growth arrest and DNA damage inducible beta
       103663135 GADD45A; growth arrest and DNA damage inducible alpha
       103665481 putative Bcl-2 homologous antagonist/killer 2
       103672315 DDB2; damage specific DNA binding protein 2
       103663562 POLK; DNA polymerase kappa
       103661742 EGF; epidermal growth factor
       103671814 TGFA; transforming growth factor alpha
       103665393 EREG; epiregulin
       103665316 AREG; amphiregulin
       103674660 EGFR; epidermal growth factor receptor
       103665736 GRB2; growth factor receptor bound protein 2
       103671891 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       103665409 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       103669173 GTPase HRas-like
       103671035 HRAS; HRas proto-oncogene, GTPase
       103669422 NRAS; neuroblastoma RAS viral oncogene homolog
       103666660 MTOR; mechanistic target of rapamycin
       103679516 RPS6KB2; ribosomal protein S6 kinase B2
       103667329 RPS6KB1; ribosomal protein S6 kinase B1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08733 APPL1; DCC-interacting protein 13 alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K02159 BAX; apoptosis regulator BAX
K16341 BCL2L11; Bcl-2-like protein 11
K10132 BBC3; Bcl-2-binding component 3
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
     05212 Pancreatic cancer [PATH:umr05212]
     05225 Hepatocellular carcinoma [PATH:umr05225]
     05226 Gastric cancer [PATH:umr05226]
     05214 Glioma [PATH:umr05214]
     05216 Thyroid cancer [PATH:umr05216]
     05221 Acute myeloid leukemia [PATH:umr05221]
     05220 Chronic myeloid leukemia [PATH:umr05220]
     05217 Basal cell carcinoma [PATH:umr05217]
     05218 Melanoma [PATH:umr05218]
     05211 Renal cell carcinoma [PATH:umr05211]
     05219 Bladder cancer [PATH:umr05219]
     05215 Prostate cancer [PATH:umr05215]
     05213 Endometrial cancer [PATH:umr05213]
     05224 Breast cancer [PATH:umr05224]
     05222 Small cell lung cancer [PATH:umr05222]
     05223 Non-small cell lung cancer [PATH:umr05223]
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
     01521 EGFR tyrosine kinase inhibitor resistance [PATH:umr01521]
     01524 Platinum drug resistance [PATH:umr01524]
       103678593 SLC31A1; solute carrier family 31 member 1
       103677629 ATP7B; ATPase copper transporting beta
       103675820 ATP7A; ATPase copper transporting alpha
       103658225 MGST3; microsomal glutathione S-transferase 3
       103657965 MGST2; microsomal glutathione S-transferase 2
       103663998 GSTA4; glutathione S-transferase alpha 4
       103663999 glutathione S-transferase A2-like
       103664000 glutathione S-transferase A4-like
       103664001 glutathione S-transferase A1
       103664002 glutathione S-transferase-like
       103675003 glutathione S-transferase Mu 1
       103675005 glutathione S-transferase Mu 1
       103675006 GSTM3; glutathione S-transferase mu 3
       103677796 MGST1; microsomal glutathione S-transferase 1
       103656766 GSTO1; glutathione S-transferase omega 1
       103656834 GSTO2; glutathione S-transferase omega 2
       103669208 glutathione S-transferase theta-1-like
       103669209 glutathione S-transferase theta-1
       103669212 glutathione S-transferase theta-2B-like
       103669279 glutathione S-transferase theta-1-like
       103669210 glutathione S-transferase theta-4-like
       103679616 glutathione S-transferase P-like
       103679521 glutathione S-transferase P-like
       103672175 uncharacterized LOC103672175
       103658893 ABCC2; ATP binding cassette subfamily C member 2
       103664061 POLH; DNA polymerase eta
       103676993 REV3L; REV3 like, DNA directed polymerase zeta catalytic subunit
       103671767 MSH2; mutS homolog 2
       103681472 MSH3; mutS homolog 3
       103671242 MSH6; mutS homolog 6
       103680847 MLH1; mutL homolog 1
       103678497 XPA; XPA, DNA damage recognition and repair factor
       103657053 ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit
       103661780 TOP2A; topoisomerase (DNA) II alpha
       103682010 TOP2B; topoisomerase (DNA) II beta
       103672599 BRCA1; BRCA1, DNA repair associated
       103662421 ATM; ATM serine/threonine kinase
       103660368 TP53; tumor protein p53
       103656869 MDM2; MDM2 proto-oncogene
       103661934 FAS; Fas cell surface death receptor
       103657107 BAX; BCL2 associated X, apoptosis regulator
       103665481 putative Bcl-2 homologous antagonist/killer 2
       103657211 BBC3; BCL2 binding component 3
       103668115 FASLG; Fas ligand
       103671072 FADD; Fas associated via death domain
       103659742 CASP8; caspase 8
       103680991 CASP3; caspase 3
       103675694 BID; BH3 interacting domain death agonist
       103662462 BIRC2; baculoviral IAP repeat containing 2
       103662463 baculoviral IAP repeat-containing protein 3-like
       103680228 XIAP; X-linked inhibitor of apoptosis
       103665963 BIRC5; baculoviral IAP repeat containing 5
       103661560 ERBB2; erb-b2 receptor tyrosine kinase 2
       103678592 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       103666874 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       103676125 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       103675162 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       103663617 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       103670766 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       103668498 PDPK1; 3-phosphoinositide dependent protein kinase 1
       103666688 AKT3; AKT serine/threonine kinase 3
       103661038 AKT2; AKT serine/threonine kinase 2
       103676878 AKT1; AKT serine/threonine kinase 1
       103665536 CDKN1A; cyclin dependent kinase inhibitor 1A
       103663496 MAP3K5; mitogen-activated protein kinase kinase kinase 5
       103669286 MAPK1; mitogen-activated protein kinase 1
       103657827 MAPK3; mitogen-activated protein kinase 3
       103679423 BAD; BCL2 associated agonist of cell death
       103674345 BCL2L1; BCL2 like 1
       103676164 BCL2; BCL2, apoptosis regulator
       103658902 cytochrome c
       103660136 APAF1; apoptotic peptidase activating factor 1
       103666628 CASP9; caspase 9
K14686 SLC31A1; solute carrier family 31 (copper transporter), member 1
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08734 MLH1; DNA mismatch repair protein MLH1
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10132 BBC3; Bcl-2-binding component 3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
     01523 Antifolate resistance [PATH:umr01523]
     01522 Endocrine resistance [PATH:umr01522]
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
     03000 Transcription factors [BR:umr03000]
     03021 Transcription machinery [BR:umr03021]
     03019 Messenger RNA biogenesis [BR:umr03019]
     03041 Spliceosome [BR:umr03041]
     03011 Ribosome [BR:umr03011]
     03009 Ribosome biogenesis [BR:umr03009]
     03016 Transfer RNA biogenesis [BR:umr03016]
     03012 Translation factors [BR:umr03012]
     03110 Chaperones and folding catalysts [BR:umr03110]
     04131 Membrane trafficking [BR:umr04131]
     04121 Ubiquitin system [BR:umr04121]
     03051 Proteasome [BR:umr03051]
     03032 DNA replication proteins [BR:umr03032]
     03036 Chromosome and associated proteins [BR:umr03036]
     03400 DNA repair and recombination proteins [BR:umr03400]
       103658228 MGMT; O-6-methylguanine-DNA methyltransferase
       103678299 ALKBH2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
       103672347 ALKBH3; alkB homolog 3, alpha-ketoglutaratedependent dioxygenase
       103675907 ASCC3; activating signal cointegrator 1 complex subunit 3
       103676459 CRY1; cryptochrome circadian clock 1
       103672397 CRY2; cryptochrome circadian clock 2
       103678346 UNG; uracil DNA glycosylase
       103663895 CCNO; cyclin O
       103676486 TDG; thymine DNA glycosylase
       103668443 MPG; N-methylpurine DNA glycosylase
       103675556 SMUG1; single-strand-selective monofunctional uracil-DNA glycosylase 1
       103670779 MUTYH; mutY DNA glycosylase
       103669535 MBD4; methyl-CpG binding domain 4, DNA glycosylase
       103669574 OGG1; 8-oxoguanine DNA glycosylase
       103679116 NEIL1; nei like DNA glycosylase 1
       103675933 NEIL2; nei like DNA glycosylase 2
       103679361 NEIL3; nei like DNA glycosylase 3
       103668778 NTHL1; nth like DNA glycosylase 1
       103656308 APEX1; apurinic/apyrimidinic endodeoxyribonuclease 1
       103682096 APEX2; apurinic/apyrimidinic endodeoxyribonuclease 2
       103657272 POLD1; DNA polymerase delta 1, catalytic subunit
       103674686 POLD2; DNA polymerase delta 2, accessory subunit
       103678051 POLD3; DNA polymerase delta 3, accessory subunit
       103679511 POLD4; DNA polymerase delta 4, accessory subunit
       103678890 POLE; DNA polymerase epsilon, catalytic subunit
       103666285 POLE2; DNA polymerase epsilon 2, accessory subunit
       103678602 POLE3; DNA polymerase epsilon 3, accessory subunit
       103663520 POLE4; DNA polymerase epsilon 4, accessory subunit
       103674409 PCNA; proliferating cell nuclear antigen
       103678171 FEN1; flap structure-specific endonuclease 1
       103657224 LIG1; DNA ligase 1
       103677058 POLB; DNA polymerase beta
       103657007 XRCC1; X-ray repair cross complementing 1
       103667279 LIG3; DNA ligase 3
       103670370 TDP1; tyrosyl-DNA phosphodiesterase 1
       103667027 APTX; aprataxin
       103671349 APLF; aprataxin and PNKP like factor
       103657264 PNKP; polynucleotide kinase 3'-phosphatase
       103664333 HMGB1; high mobility group box 1
       103668179 high mobility group protein B1-like
       103658987 POLL; DNA polymerase lambda
       103669036 PARP1; poly(ADP-ribose) polymerase 1
       103664268 PARP4; poly(ADP-ribose) polymerase family member 4
       103656304 PARP2; poly(ADP-ribose) polymerase 2
       103674775 PARP3; poly(ADP-ribose) polymerase family member 3
       103669510 XPC; XPC complex subunit, DNA damage recognition and repair factor
       103682145 RAD23A; RAD23 homolog A, nucleotide excision repair protein
       103678550 RAD23B; RAD23 homolog B, nucleotide excision repair protein
       103674164 CETN2; centrin 2
       103674160 RBX1; ring-box 1
       103657525 CUL4A; cullin 4A
       103680235 CUL4B; cullin 4B
       103678159 DDB1; damage specific DNA binding protein 1
       103672315 DDB2; damage specific DNA binding protein 2
       103660476 POLR2A; RNA polymerase II subunit A
       103672816 POLR2B; RNA polymerase II subunit B
       103673892 POLR2C; RNA polymerase II subunit C
       103658564 POLR2D; RNA polymerase II subunit D
       103681776 POLR2E; RNA polymerase II subunit E
       103676392 POLR2F; RNA polymerase II subunit F
       103678202 POLR2G; RNA polymerase II subunit G
       103676079 POLR2H; RNA polymerase II subunit H
       103682534 POLR2I; RNA polymerase II subunit I
       103671102 POLR2L; RNA polymerase II subunit L
       103670139 POLR2J; RNA polymerase II subunit J
       103661503 POLR2K; RNA polymerase II subunit K
       103663651 ERCC8; ERCC excision repair 8, CSA ubiquitin ligase complex subunit
       103667902 ERCC6; ERCC excision repair 6, chromatin remodeling factor
       103676937 UVSSA; UV stimulated scaffold protein A
       103658572 ERCC3; ERCC excision repair 3, TFIIH core complex helicase subunit
       103657184 ERCC2; ERCC excision repair 2, TFIIH core complex helicase subunit
       103659412 GTF2H1; general transcription factor IIH subunit 1
       103663603 GTF2H2C; GTF2H2 family member C
       103661127 GTF2H3; general transcription factor IIH subunit 3
       103665011 GTF2H4; general transcription factor IIH subunit 4
       103660850 GTF2H5; general transcription factor IIH subunit 5
       103663610 CDK7; cyclin dependent kinase 7
       103672148 CCNH; cyclin H
       103672572 MNAT1; MNAT1, CDK activating kinase assembly factor
       103667158 RPA1; replication protein A1
       103666754 RPA2; replication protein A2
       103658764 RPA3; replication protein A3
       103673017 RPA4; replication protein A4
       103678497 XPA; XPA, DNA damage recognition and repair factor
       103657053 ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit
       103668836 ERCC4; ERCC excision repair 4, endonuclease catalytic subunit
       103657553 DNA repair protein complementing XP-G cells-like
       103673169 MMS19; MMS19 homolog, cytosolic iron-sulfur assembly component
       103662718 CUL3; cullin 3
       103662541 CUL5; cullin 5
       103681263 ELOC; elongin C
       103657431 transcription elongation factor B polypeptide 2-like
       103668800 ELOB; elongin B
       103666558 ELOA; elongin A
       103671767 MSH2; mutS homolog 2
       103681472 MSH3; mutS homolog 3
       103671242 MSH6; mutS homolog 6
       103662996 MSH4; mutS homolog 4
       103682297 MSH5; mutS homolog 5
       103659673 PMS1; PMS1 homolog 1, mismatch repair system component
       103680847 MLH1; mutL homolog 1
       103669972 PMS2; PMS1 homolog 2, mismatch repair system component
       103671057 MLH3; mutL homolog 3
       103672677 RFC1; replication factor C subunit 1
       103676051 RFC4; replication factor C subunit 4
       103670233 RFC2; replication factor C subunit 2
       103661224 RFC5; replication factor C subunit 5
       103664364 RFC3; replication factor C subunit 3
       103666634 EXO1; exonuclease 1
       103673388 WDR76; WD repeat domain 76
       103660707 MRE11; MRE11 homolog, double strand break repair nuclease
       103663834 RAD50; RAD50 double strand break repair protein
       103661472 NBN; nibrin
       103672599 BRCA1; BRCA1, DNA repair associated
       103662899 BARD1; BRCA1 associated RING domain 1
       103665421 FAM175A; family with sequence similarity 175 member A
       103664760 UIMC1; ubiquitin interaction motif containing 1
       103674961 BABAM1; BRISC and BRCA1 A complex member 1
       103671625 BRE; brain and reproductive organ-expressed (TNFRSF1A modulator)
       103659292 BRCC3; BRCA1/BRCA2-containing complex subunit 3
       103667455 BRIP1; BRCA1 interacting protein C-terminal helicase 1
       103679022 TOPBP1; topoisomerase (DNA) II binding protein 1
       103662987 RBBP8; RB binding protein 8, endonuclease
       103664352 BRCA2; BRCA2, DNA repair associated
       103668856 PALB2; partner and localizer of BRCA2
       103673456 RAD51; RAD51 recombinase
       103671745 RAD51B; RAD51 paralog B
       103667345 RAD51C; RAD51 paralog C
       103667434 RAD51D; RAD51 paralog D
       103660935 XRCC2; X-ray repair cross complementing 2
       103676921 XRCC3; X-ray repair cross complementing 3
       103676384 DMC1; DNA meiotic recombinase 1
       103675716 RAD52; RAD52 homolog, DNA repair protein
       103665607 RDM1; RAD52 motif containing 1
       103670759 RAD54L; RAD54-like (S. cerevisiae)
       103674784 RAD54L2; RAD54-like 2 (S. cerevisiae)
       103661439 RAD54B; RAD54 homolog B (S. cerevisiae)
       103665225 RECQL; RecQ like helicase
       103659100 WRN; Werner syndrome RecQ like helicase
       103660200 BLM; Bloom syndrome RecQ like helicase
       103656685 RECQL4; RecQ like helicase 4
       103665741 RECQL5; RecQ like helicase 5
       103658498 TOP3A; topoisomerase (DNA) III alpha
       103669218 TOP3B; topoisomerase (DNA) III beta
       103667629 RMI1; RecQ mediated genome instability 1
       103657830 PPP4C; protein phosphatase 4 catalytic subunit
       103662378 PPP4R1; protein phosphatase 4 regulatory subunit 1
       103670942 putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like
       103674258 PPP4R2; protein phosphatase 4 regulatory subunit 2
       103673811 PPP4R3A; protein phosphatase 4 regulatory subunit 3A
       103671275 PPP4R3B; protein phosphatase 4 regulatory subunit 3B
       103668194 serine/threonine-protein phosphatase 4 regulatory subunit 3B-like
       103673735 PPP4R4; protein phosphatase 4 regulatory subunit 4
       103679586 AP5B1; adaptor related protein complex 5 beta 1 subunit
       103673258 AP5M1; adaptor related protein complex 5 mu 1 subunit
       103674394 AP5S1; adaptor related protein complex 5 sigma 1 subunit
       103670080 AP5Z1; adaptor related protein complex 5 zeta 1 subunit
       103663252 SMC5; structural maintenance of chromosomes 5
       103671718 SMC6; structural maintenance of chromosomes 6
       103671951 FAM84A; family with sequence similarity 84 member A
       103657808 NSMCE1; NSE1 homolog, SMC5-SMC6 complex component
       103661627 NSMCE2; NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
       103659973 NSMCE3; NSE3 homolog, SMC5-SMC6 complex component
       103657843 NSMCE4A; NSE4 homolog A, SMC5-SMC6 complex component
       103676481 EID3; EP300 interacting inhibitor of differentiation 3
       103660591 synaptonemal complex protein 2-like
       103676504 SYCP3; synaptonemal complex protein 3
       103660413 EME1; essential meiotic structure-specific endonuclease 1
       103671636 EXD2; exonuclease 3'-5' domain containing 2
       103663097 HFM1; HFM1, ATP dependent DNA helicase homolog
       103679589 MUS81; MUS81 structure-specific endonuclease subunit
       103657400 26S proteasome complex subunit DSS1-like
       103670950 SPO11; SPO11, initiator of meiotic double stranded breaks
       103657914 SLX1A; SLX1 homolog A, structure-specific endonuclease subunit
       103668809 SLX4; SLX4 structure-specific endonuclease subunit
       103671717 GEN1; GEN1, Holliday junction 5' flap endonuclease
       103673381 SPG11; spastic paraplegia 11 (autosomal recessive)
       103671836 ZFYVE26; zinc finger FYVE-type containing 26
       103675751 RAD51AP1; RAD51 associated protein 1
       103660297 MORF4L1; mortality factor 4 like 1
       103668481 MEIOB; meiosis specific with OB domains
       103667139 SPATA22; spermatogenesis associated 22
       103669780 SAMHD1; SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
       103674554 FIGNL1; fidgetin like 1
       103677408 SPIDR; scaffolding protein involved in DNA repair
       103670073 BRAT1; BRCA1 associated ATM activator 1
       103680749 CUNH21orf2; chromosome unknown C21orf2 homolog
       103674078 XRCC6; X-ray repair cross complementing 6
       103662783 XRCC5; X-ray repair cross complementing 5
       103677407 PRKDC; protein kinase, DNA-activated, catalytic polypeptide
       103657546 LIG4; DNA ligase 4
       103677136 XRCC4; X-ray repair cross complementing 4
       103662751 NHEJ1; non-homologous end joining factor 1
       103674688 POLM; DNA polymerase mu
       103672419 DNTT; DNA nucleotidylexotransferase
       103664190 DCLRE1C; DNA cross-link repair 1C
       103665179 TDP2; tyrosyl-DNA phosphodiesterase 2
       103662690 SMCHD1; structural maintenance of chromosomes flexible hinge domain containing 1
       103668910 MUM1L1; MUM1 like 1
       103679708 PWWP domain-containing protein MUM1L1-like
       103681782 PWWP domain-containing protein MUM1
       103673972 FANCA; Fanconi anemia complementation group A
       103668114 FANCB; Fanconi anemia complementation group B
       103682212 FANCC; Fanconi anemia complementation group C
       103665462 FANCE; Fanconi anemia complementation group E
       103659382 FANCF; Fanconi anemia complementation group F
       103667064 FANCG; Fanconi anemia complementation group G
       103671282 FANCL; Fanconi anemia complementation group L
       103665654 FANCM; Fanconi anemia complementation group M
       103661336 FAAP24; Fanconi anemia core complex associated protein 24
       103665993 FAAP100; Fanconi anemia core complex associated protein 100
       103676171 HES1; hes family bHLH transcription factor 1
       103666872 centromere protein S-like
       103665825 CENPX; centromere protein X
       103657719 UBE2T; ubiquitin conjugating enzyme E2 T
       103669643 FANCD2; Fanconi anemia complementation group D2
       103660177 FANCI; Fanconi anemia complementation group I
       103659969 FAN1; FANCD2 and FANCI associated nuclease 1
       103668767 telomere length regulation protein TEL2 homolog
       103663070 USP1; ubiquitin specific peptidase 1
       103680603 WDR48; WD repeat domain 48
       103670456 PPP6C; protein phosphatase 6 catalytic subunit
       103680306 PPP6R1; protein phosphatase 6 regulatory subunit 1
       103674003 PPP6R2; protein phosphatase 6 regulatory subunit 2
       103679531 PPP6R3; protein phosphatase 6 regulatory subunit 3
       103679404 ANKRD28; ankyrin repeat domain 28
       103659707 ANKRD44; ankyrin repeat domain 44
       103656930 ANKRD52; ankyrin repeat domain 52
       103665434 RNF8; ring finger protein 8
       103678933 RNF168; ring finger protein 168
       103678119 RNF169; ring finger protein 169
       103677087 HERC2; HECT and RLD domain containing E3 ubiquitin protein ligase 2
       103660369 WRAP53; WD repeat containing antisense to TP53
       103675314 TPRN; taperin
       103670026 ZCWPW1; zinc finger CW-type and PWWP domain containing 1
       103664697 WDR70; WD repeat domain 70
       103664061 POLH; DNA polymerase eta
       103664376 POLI; DNA polymerase iota
       103663562 POLK; DNA polymerase kappa
       103671167 REV1; REV1, DNA directed polymerase
       103676993 REV3L; REV3 like, DNA directed polymerase zeta catalytic subunit
       103676577 POLN; DNA polymerase nu
       103677738 UBE2A; ubiquitin conjugating enzyme E2 A
       103663813 UBE2B; ubiquitin conjugating enzyme E2 B
       103669584 RAD18; RAD18, E3 ubiquitin protein ligase
       103678072 HLTF; helicase like transcription factor
       103677417 UBE2V2; ubiquitin conjugating enzyme E2 V2
       103660152 UBE2N; ubiquitin conjugating enzyme E2 N
       103667777 ubiquitin-conjugating enzyme E2 N-like
       103666908 ARMT1; acidic residue methyltransferase 1
       103661876 SPRTN; SprT-like N-terminal domain
       103679610 RAD9A; RAD9 checkpoint clamp component A
       103661178 RAD9B; RAD9 checkpoint clamp component B
       103674670 HUS1; HUS1 checkpoint clamp component
       103664981 HUS1B; HUS1 checkpoint clamp component B
       103664724 RAD1; RAD1 checkpoint DNA exonuclease
       103663604 RAD17; RAD17 checkpoint clamp loader component
       103656241 TIMELESS; timeless circadian clock
       103679067 TIPIN; TIMELESS interacting protein
       103669771 TTI1; TELO2 interacting protein 1
       103681353 TTI2; TELO2 interacting protein 2
       103682313 BAG6; BCL2 associated athanogene 6
       103679683 UBL4A; ubiquitin like 4A
       103675206 UBL4B; ubiquitin like 4B
       103670056 GET4; golgi to ER traffic protein 4
       103678381 ATR; ATR serine/threonine kinase
       103674851 ATRIP; ATR interacting protein
       103662421 ATM; ATM serine/threonine kinase
       103660368 TP53; tumor protein p53
       103660629 CHEK1; checkpoint kinase 1
       103659236 CHEK2; checkpoint kinase 2
       103675112 CDC25A; cell division cycle 25A
       103674532 CDC25B; cell division cycle 25B
       103663783 M-phase inducer phosphatase 3-like
       103661509 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
       103675032 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
       103669726 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
       103681113 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
       103670210 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
       103667175 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
       103659389 NAV2; neuron navigator 2
       103656401 WEE1; WEE1 G2 checkpoint kinase
       103669018 WEE2; WEE1 homolog 2
       103660489 PER1; period circadian clock 1
       103662618 PER2; period circadian clock 2
       103666883 PER3; period circadian clock 3
       103665003 MDC1; mediator of DNA damage checkpoint 1
       103679749 PLS3; plastin 3
       103660250 AEN; apoptosis enhancing nuclease
       103670899 PLK3; polo like kinase 3
       103674753 NEK4; NIMA related kinase 4
       103658148 NEK1; NIMA related kinase 1
       103677632 NEK5; NIMA related kinase 5
       103679872 NEK10; NIMA related kinase 10
       103679205 NEK11; NIMA related kinase 11
       103673222 DONSON; downstream neighbor of SON
       103663072 KANK4; KN motif and ankyrin repeat domains 4
       103663334 KANK1; KN motif and ankyrin repeat domains 1
       103678679 KANK2; KN motif and ankyrin repeat domains 2
       103681883 KANK3; KN motif and ankyrin repeat domains 3
       103661998 KLLN; killin, p53-regulated DNA replication inhibitor
       103678778 POLQ; DNA polymerase theta
       103660420 MYBBP1A; MYB binding protein 1a
       103680990 PRIMPOL; primase and DNA directed polymerase
       103674850 TREX1; three prime repair exonuclease 1
       103657341 DCLRE1A; DNA cross-link repair 1A
       103669432 DCLRE1B; DNA cross-link repair 1B
       103682386 EXO5; exonuclease 5
       103665981 ENDOV; endonuclease V
       103675183 ANKLE1; ankyrin repeat and LEM domain containing 1
       103665373 HELQ; helicase, POLQ-like
       103682214 ERCC6L2; ERCC excision repair 6 like 2
       103678218 PRPF19; pre-mRNA processing factor 19
       103664046 CDC5L; cell division cycle 5 like
       103669425 BCAS2; BCAS2, pre-mRNA processing factor
       103658032 PLRG1; pleiotropic regulator 1
       103677596 NUDT15; nudix hydrolase 15
       103669938 NUDT1; nudix hydrolase 1
       103673345 NUDT18; nudix hydrolase 18
       103676713 DUT; deoxyuridine triphosphatase
       103678102 RRM1; ribonucleotide reductase catalytic subunit M1
       103661517 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
       103660736 RRM2; ribonucleotide reductase regulatory subunit M2
       103669017 SSBP1; single stranded DNA binding protein 1
K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:3.6.4.12]
K02295 CRY; cryptochrome
K02295 CRY; cryptochrome
K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
K10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]
K10569 NEIL3; endonuclease VIII-like 3
K10773 NTH; endonuclease III [EC:4.2.99.18]
K10771 APEX1; AP endonuclease 1 [EC:4.2.99.18]
K10772 APEX2; AP endonuclease 2 [EC:4.2.99.18]
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K04802 PCNA; proliferating cell nuclear antigen
K04799 FEN1; flap endonuclease-1 [EC:3.-.-.-]
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K10803 XRCC1; DNA-repair protein XRCC1
K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
K13295 APLF; aprataxin and PNK-like factor [EC:4.2.99.18]
K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
K10802 HMGB1; high mobility group protein B1
K10802 HMGB1; high mobility group protein B1
K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10838 XPC; xeroderma pigmentosum group C-complementing protein
K10839 RAD23; UV excision repair protein RAD23
K10839 RAD23; UV excision repair protein RAD23
K10840 CETN2; centrin-2
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K10609 CUL4; cullin 4
K10609 CUL4; cullin 4
K10610 DDB1; DNA damage-binding protein 1
K10140 DDB2; DNA damage-binding protein 2
K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
K03013 RPB5; DNA-directed RNA polymerases I, II, and III subunit RPABC1
K03014 RPB6; DNA-directed RNA polymerases I, II, and III subunit RPABC2
K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
K03016 RPB8; DNA-directed RNA polymerases I, II, and III subunit RPABC3
K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
K03007 RPB10; DNA-directed RNA polymerases I, II, and III subunit RPABC5
K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
K03009 RPB12; DNA-directed RNA polymerases I, II, and III subunit RPABC4
K10570 ERCC8; DNA excision repair protein ERCC-8
K10841 ERCC6; DNA excision repair protein ERCC-6
K23720 UVSSA; UV-stimulated scaffold protein A
K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:3.6.4.12]
K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:3.6.4.12]
K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K06634 CCNH; cyclin H
K10842 MNAT1; CDK-activating kinase assembly factor MAT1
K07466 RFA1; replication factor A1
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K10741 RPA4; replication factor A4
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K10846 ERCC5; DNA excision repair protein ERCC-5
K15075 MET18; DNA repair/transcription protein MET18/MMS19
K03869 CUL3; cullin 3
K10612 CUL5; cullin 5
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03873 ELOB; elongin-B
K15076 ELOA; elongin-A
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08740 MSH4; DNA mismatch repair protein MSH4
K08741 MSH5; DNA mismatch repair protein MSH5
K10864 PMS1; DNA mismatch repair protein PMS1
K08734 MLH1; DNA mismatch repair protein MLH1
K10858 PMS2; DNA mismatch repair protein PMS2
K08739 MLH3; DNA mismatch repair protein MLH3
K10754 RFC1; replication factor C subunit 1
K10755 RFC2_4; replication factor C subunit 2/4
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K10756 RFC3_5; replication factor C subunit 3/5
K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
K24755 
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K10683 BARD1; BRCA1-associated RING domain protein 1
K20774 FAM175A; BRCA1-A complex subunit Abraxas
K20775 UIMC1; BRCA1-A complex subunit RAP80
K20776 BABAM; BRISC and BRCA1-A complex member 1
K12173 BRE; BRCA1-A complex subunit BRE
K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
K15362 BRIP1; fanconi anemia group J protein [EC:3.6.4.12]
K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]
K08775 BRCA2; breast cancer 2 susceptibility protein
K10897 PALB2; partner and localizer of BRCA2
K04482 RAD51; DNA repair protein RAD51
K10869 RAD51L1; RAD51-like protein 1
K10870 RAD51L2; RAD51-like protein 2
K10871 RAD51L3; RAD51-like protein 3
K10879 XRCC2; DNA-repair protein XRCC2
K10880 XRCC3; DNA-repair protein XRCC3
K10872 DMC1; meiotic recombination protein DMC1
K10873 RAD52; DNA repair and recombination protein RAD52
K10874 RDM1; RAD52 motif-containing protein 1
K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:3.6.4.-]
K10876 RAD54L2; RAD54-like protein 2 [EC:3.6.4.12]
K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:3.6.4.-]
K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:3.6.4.12]
K10900 WRN; werner syndrome ATP-dependent helicase [EC:3.6.4.12]
K10901 BLM; bloom syndrome protein [EC:3.6.4.12]
K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:3.6.4.12]
K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:3.6.4.12]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K10990 RMI1; RecQ-mediated genome instability protein 1
K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
K19022 AP5B1; AP-5 complex subunit beta-1
K19023 AP5M1; AP-5 complex subunit mu-1
K19024 AP5S1; AP-5 complex subunit sigma-1
K19025 AP5Z1; AP-5 complex subunit zeta-1
K22803 SMC5; structural maintenance of chromosomes protein 5
K22804 SMC6; structural maintenance of chromosomes protein 6
K22805 FAM84A; protein FAM84A
K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
K22823 NSMCE3; non-structural maintenance of chromosomes element 3
K22825 NSMCE4; non-structural maintenance of chromosomes element 4
K22826 EID3; EP300-interacting inhibitor of differentiation 3
K19529 SYCP2; synaptonemal complex protein 2
K19528 SYCP3; synaptonemal complex protein 3
K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
K15271 HFM1; ATP-dependent DNA helicase HFM1/MER3 [EC:3.6.4.12]
K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
K10881 SHFM1; 26 proteasome complex subunit DSS1
K10878 SPO11; meiotic recombination protein SPO11
K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
K15338 GEN1; flap endonuclease GEN [EC:3.1.-.-]
K19026 SPG11; spatacsin
K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
K20778 RAD51AP1; RAD51-associated protein 1
K11339 MORF4L1; mortality factor 4-like protein 1
K22420 MEIOB; meiosis-specific with OB domain-containing protein [EC:3.1.-.-]
K22421 SPATA22; spermatogenesis-associated protein 22
K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
K22766 FIGNL1; fidgetin-like protein 1 [EC:3.6.4.-]
K22806 SPIDR; DNA repair-scaffolding protein
K23112 BRAT1; BRCA1-associated ATM activator 1
K23456 CFAP410; cilla- and flagella-associated protein
K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
K10886 XRCC4; DNA-repair protein XRCC4
K10980 NHEJ1; non-homologous end-joining factor 1
K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
K23386 PWWP3; PWWP domain-containing DNA repair factor 3
K23386 PWWP3; PWWP domain-containing DNA repair factor 3
K23386 PWWP3; PWWP domain-containing DNA repair factor 3
K10888 FANCA; fanconi anemia group A protein
K10889 FANCB; fanconi anemia group B protein
K10890 FANCC; fanconi anemia group C protein
K10892 FANCE; fanconi anemia group E protein
K10893 FANCF; fanconi anemia group F protein
K10894 FANCG; fanconi anemia group G protein
K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
K10896 FANCM; fanconi anemia group M protein
K10898 FAAP24; fanconi anemia-associated protein
K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
K06054 HES1; hairy and enhancer of split 1
K11511 APITD1; centromere protein S
K15360 STRA13; centromere protein X
K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
K10891 FANCD2; fanconi anemia group D2 protein
K10895 FANCI; fanconi anemia group I protein
K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
K11137 TELO2; telomere length regulation protein
K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
K15361 WDR48; WD repeat-containing protein 48
K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
K15499 PPP6R1; serine/threonine-protein phosphatase 6 regulatory subunit 1
K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
K23314 WRAP53; telomerase Cajal body protein 1
K24164 TPRN; taperin
K24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1
K24752 
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:3.6.4.- 2.3.2.27]
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K23114 ARMT1; protein-glutamate O-methyltransferase [EC:2.1.1.-]
K24051 SPRTN; SprT-like domain-contaning protein Spartan
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K10903 HUS1; HUS1 checkpoint protein
K10996 HUS1B; checkpoint protein HUS1B
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K06662 HRAD17; cell cycle checkpoint protein
K03155 TIMELESS; timeless
K10904 TIPIN; TIMELESS-interacting protein
K20403 TTI1; TELO2-interacting protein 1
K23115 TTI2; TELO2-interacting protein 2
K23390 BAG6; large proline-rich protein BAG6
K23388 UBL4; ubiquitin-like protein 4
K23388 UBL4; ubiquitin-like protein 4
K23387 GET4; golgi to ER traffic protein 4
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K10905 ATRIP; ATR interacting protein
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06630 YWHAE; 14-3-3 protein epsilon
K19483 NAV2; neuron navigator 2 [EC:3.6.4.12]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K21944 PER1; period circadian protein 1
K02633 PER2; period circadian protein 2
K21945 PER3; period circadian protein 3
K20780 MDC1; mediator of DNA damage checkpoint protein 1
K17336 PLS3; plastin-3
K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08857 NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]
K08857 NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]
K08857 NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]
K20879 NEK10; NIMA (never in mitosis gene a)-related kinase 10 [EC:2.7.11.1]
K20880 NEK11; NIMA (never in mitosis gene a)-related kinase 11 [EC:2.7.11.1]
K22422 DONSON; protein downstream neighbor of Son
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K23389 KLLN; killin
K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
K15340 DCLRE1A; DNA cross-link repair 1A protein
K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
K17815 EXO5; exonuclease V [EC:3.1.-.-]
K21813 ENDOV; endonuclease V [EC:3.1.26.-]
K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
K19178 HELQ; POLQ-like helicase [EC:3.6.4.12]
K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:3.6.4.-]
K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
K12861 BCAS2; pre-mRNA-splicing factor SPF27
K12862 PLRG1; pleiotropic regulator 1
K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
K01520 dut; dUTP pyrophosphatase [EC:3.6.1.23]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K03111 ssb; single-strand DNA-binding protein
     03029 Mitochondrial biogenesis [BR:umr03029]
 
   09183 Protein families: signaling and cellular processes
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: February 24, 2021