Search BRITE hierarchies

KEGG Orthology (KO) [BR:aml00001]
  09130 Environmental Information Processing
    09132 Signal transduction
      04010 MAPK signaling pathway [PATH:aml04010]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04014 Ras signaling pathway [PATH:aml04014]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04310 Wnt signaling pathway [PATH:aml04310]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04340 Hedgehog signaling pathway [PATH:aml04340]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04371 Apelin signaling pathway [PATH:aml04371]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04020 Calcium signaling pathway [PATH:aml04020]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04024 cAMP signaling pathway [PATH:aml04024]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
  09140 Cellular Processes
    09141 Transport and catabolism
      04140 Autophagy - animal [PATH:aml04140]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09143 Cell growth and death
      04114 Oocyte meiosis [PATH:aml04114]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09144 Cellular community - eukaryotes
      04530 Tight junction [PATH:aml04530]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04540 Gap junction [PATH:aml04540]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
  09150 Organismal Systems
    09151 Immune system
      04611 Platelet activation [PATH:aml04611]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04062 Chemokine signaling pathway [PATH:aml04062]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09152 Endocrine system
      04911 Insulin secretion [PATH:aml04911]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04910 Insulin signaling pathway [PATH:aml04910]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04922 Glucagon signaling pathway [PATH:aml04922]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04923 Regulation of lipolysis in adipocytes [PATH:aml04923]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04912 GnRH signaling pathway [PATH:aml04912]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04913 Ovarian steroidogenesis [PATH:aml04913]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04915 Estrogen signaling pathway [PATH:aml04915]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04914 Progesterone-mediated oocyte maturation [PATH:aml04914]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04921 Oxytocin signaling pathway [PATH:aml04921]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04926 Relaxin signaling pathway [PATH:aml04926]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04935 Growth hormone synthesis, secretion and action [PATH:aml04935]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04918 Thyroid hormone synthesis [PATH:aml04918]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04919 Thyroid hormone signaling pathway [PATH:aml04919]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04928 Parathyroid hormone synthesis, secretion and action [PATH:aml04928]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04916 Melanogenesis [PATH:aml04916]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04924 Renin secretion [PATH:aml04924]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04925 Aldosterone synthesis and secretion [PATH:aml04925]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04927 Cortisol synthesis and secretion [PATH:aml04927]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09153 Circulatory system
      04261 Adrenergic signaling in cardiomyocytes [PATH:aml04261]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04270 Vascular smooth muscle contraction [PATH:aml04270]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09154 Digestive system
      04970 Salivary secretion [PATH:aml04970]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04971 Gastric acid secretion [PATH:aml04971]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04976 Bile secretion [PATH:aml04976]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09155 Excretory system
      04962 Vasopressin-regulated water reabsorption [PATH:aml04962]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04961 Endocrine and other factor-regulated calcium reabsorption [PATH:aml04961]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09156 Nervous system
      04724 Glutamatergic synapse [PATH:aml04724]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04727 GABAergic synapse [PATH:aml04727]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04725 Cholinergic synapse [PATH:aml04725]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04728 Dopaminergic synapse [PATH:aml04728]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04726 Serotonergic synapse [PATH:aml04726]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04720 Long-term potentiation [PATH:aml04720]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04723 Retrograde endocannabinoid signaling [PATH:aml04723]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09157 Sensory system
      04740 Olfactory transduction [PATH:aml04740]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04742 Taste transduction [PATH:aml04742]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04750 Inflammatory mediator regulation of TRP channels [PATH:aml04750]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09149 Aging
      04211 Longevity regulating pathway [PATH:aml04211]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04213 Longevity regulating pathway - multiple species [PATH:aml04213]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09159 Environmental adaptation
      04713 Circadian entrainment [PATH:aml04713]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      04714 Thermogenesis [PATH:aml04714]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
  09160 Human Diseases
    09161 Cancer: overview
      05200 Pathways in cancer [PATH:aml05200]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      05205 Proteoglycans in cancer [PATH:aml05205]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      05207 Chemical carcinogenesis - receptor activation [PATH:aml05207]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      05203 Viral carcinogenesis [PATH:aml05203]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09172 Infectious disease: viral
      05166 Human T-cell leukemia virus 1 infection [PATH:aml05166]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      05163 Human cytomegalovirus infection [PATH:aml05163]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      05165 Human papillomavirus infection [PATH:aml05165]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09174 Infectious disease: parasitic
      05146 Amoebiasis [PATH:aml05146]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09164 Neurodegenerative disease
      05012 Parkinson disease [PATH:aml05012]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      05020 Prion disease [PATH:aml05020]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09165 Substance dependence
      05030 Cocaine addiction [PATH:aml05030]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      05031 Amphetamine addiction [PATH:aml05031]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      05032 Morphine addiction [PATH:aml05032]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      05034 Alcoholism [PATH:aml05034]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09166 Cardiovascular disease
      05414 Dilated cardiomyopathy [PATH:aml05414]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09167 Endocrine and metabolic disease
      04934 Cushing syndrome [PATH:aml04934]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09176 Drug resistance: antineoplastic
      01522 Endocrine resistance [PATH:aml01522]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
  09180 Brite Hierarchies
    09181 Protein families: metabolism
      01001 Protein kinases [BR:aml01001]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
    09182 Protein families: genetic information processing
      03019 Messenger RNA biogenesis [BR:aml03019]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]
      03036 Chromosome and associated proteins [BR:aml03036]
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11]

Enzymes [BR:aml01000]
  2. Transferases
    2.7  Transferring phosphorus-containing groups
      2.7.11  Protein-serine/threonine kinases
        2.7.11.11  cAMP-dependent protein kinase
          100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11] 

Protein kinases [BR:aml01001]
  Serine/threonine kinases: AGC group
    PKA family
      100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11] 

Messenger RNA biogenesis [BR:aml03019]
  Eukaryotic type
    mRNA surveillance and transport factors
      mRNA cycle factors
        Common to processing body (P body) and stress granule
          100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11] 

Chromosome and associated proteins [BR:aml03036]
  Eukaryotic type
    Centrosome formation proteins
      Kinases and associated factors
        100468252 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2	K04345 PKA; protein kinase A [EC:2.7.11.11] 

[ BRITE | KEGG2 | KEGG ]