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KEGG Orthology (KO) [BR:hsa00001]
  09130 Environmental Information Processing
    09132 Signal transduction
      04151 PI3K-Akt signaling pathway [PATH:hsa04151]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
  09140 Cellular Processes
    09143 Cell growth and death
      04110 Cell cycle [PATH:hsa04110]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      04115 p53 signaling pathway [PATH:hsa04115]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      04218 Cellular senescence [PATH:hsa04218]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
    09144 Cellular community - eukaryotes
      04530 Tight junction [PATH:hsa04530]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
  09150 Organismal Systems
    09151 Immune system
      04660 T cell receptor signaling pathway [PATH:hsa04660]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
  09160 Human Diseases
    09161 Cancer: overview
      05200 Pathways in cancer [PATH:hsa05200]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05203 Viral carcinogenesis [PATH:hsa05203]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
    09162 Cancer: specific types
      05212 Pancreatic cancer [PATH:hsa05212]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05225 Hepatocellular carcinoma [PATH:hsa05225]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05214 Glioma [PATH:hsa05214]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05220 Chronic myeloid leukemia [PATH:hsa05220]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05218 Melanoma [PATH:hsa05218]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05219 Bladder cancer [PATH:hsa05219]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05224 Breast cancer [PATH:hsa05224]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05222 Small cell lung cancer [PATH:hsa05222]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05223 Non-small cell lung cancer [PATH:hsa05223]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
    09167 Endocrine and metabolic disease
      04933 AGE-RAGE signaling pathway in diabetic complications [PATH:hsa04933]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      04934 Cushing syndrome [PATH:hsa04934]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
    09172 Infectious disease: viral
      05166 Human T-cell leukemia virus 1 infection [PATH:hsa05166]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05162 Measles [PATH:hsa05162]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05164 Influenza A [PATH:hsa05164]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05160 Hepatitis C [PATH:hsa05160]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05163 Human cytomegalovirus infection [PATH:hsa05163]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05167 Kaposi sarcoma-associated herpesvirus infection [PATH:hsa05167]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05169 Epstein-Barr virus infection [PATH:hsa05169]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
      05165 Human papillomavirus infection [PATH:hsa05165]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
    09176 Drug resistance: antineoplastic
      01522 Endocrine resistance [PATH:hsa01522]
        1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]

Enzymes [BR:hsa01000]
  2. Transferases
    2.7  Transferring phosphorus-containing groups
      2.7.11  Protein-serine/threonine kinases
        2.7.11.22  cyclin-dependent kinase
          1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22] 

Protein kinases [BR:hsa01001]
  Serine/threonine kinases: CMGC group
    CDK family
      1019 CDK4; cyclin dependent kinase 4	K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22] 

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