| Entry |
Thumbnail Image |
Name |
Description |
Object |
Legend |
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hsa01100
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Metabolic pathways |
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...gin) C12434 ((S)-DNPA) C18356 ((S)-Hemiketal) C18354 ((S)-Chiral alcohol) C18709 (Decaketide tricycl... |
Metabolism of Terpenoids and Polyketides Lipid Metabolism Glycan Biosynthesis and Metabolism Carbohy... |
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hsa04613
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Neutrophil extracellular trap formation |
Neutrophils play a central role in innate immune defense. One of the mechanisms of neutrophil action... |
... (H3C1), 8351 (H3C4), 8352 (H3C3), 8353 (H3C6), 8354 (H3C11), 8355 (H3C8), 8356 (H3C12), 8357 (H3C10... |
Neutrophil FcγRIIA FcγRI Src Syk IgG PI3K PIP PLC DAG PKC Raf1 MEK ERK1/2 Akt NOD-like receptor si... |
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hsa00240
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Pyrimidine metabolism |
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...TPD3) 139596 (UPRT) 54963 (UCKL1), 7371 (UCK2), 83549 (UCK1) 100526794 (NT5C1B-RDH14), 115024 (NT5C3... |
(extracellular) CTP 1.17.4.1 3-Oxo-3-ureido-propanoate 3.5.1.95 2.7.4.22 3.5.4.30 2.1.1.148 L-Glutam... |
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hsa00983
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Drug metabolism - other enzymes |
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... (UPB1) 7372 (UMPS) 54963 (UCKL1), 7371 (UCK2), 83549 (UCK1) 7083 (TK1), 7084 (TK2) 3614 (IMPDH1), 3... |
Isoniazid 6-Thioinosine-5'-monophosphate Capecitabine Isonicotinic acid DRUG METABOLISM - OTHER ENZ... |
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hsa04145
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Phagosome |
Phagocytosis is the process of taking in relatively large particles by a cell, and is a central mech... |
...RAB5C) 338382 (RAB7B), 7879 (RAB7A) 1536 (CYBB) 83547 (RILP) 1535 (CYBA) 4689 (NCF4) 653361 (NCF1) 4... |
PHAGOSOME Fc gamma R-mediated phagocytosis Endocytosis Phagocytic cup pathogen Conventional p... |
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hsa05014
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Amyotrophic lateral sclerosis |
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by a progressive d... |
...), 56171 (DNAH7), 64446 (DNAI2), 7802 (DNALI1), 83544 (DNAL1), 8632 (DNAH17), 8701 (DNAH11) 10376 (T... |
SOD1 EAAT2 AMYOTROPHIC LATERAL SCLEROSIS Motor neuron Astrocyte Presynaptic neuron Microglial cell... |
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hsa05016
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Huntington disease |
Huntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects m... |
...), 56171 (DNAH7), 64446 (DNAI2), 7802 (DNALI1), 83544 (DNAL1), 8632 (DNAH17), 8701 (DNAH11) 7052 (TG... |
HUNTINGTON DISEASE Cx I Cx II Cx III Cx IV Cx V Htt Htt Htt Htt Htt REST REST coREST Sin3A HDACs DN... |
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hsa05022
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Pathways of neurodegeneration - multiple diseases |
Neurodegeneration is generally defined as progressive, irreversible loss of neurons, which may affec... |
...), 56171 (DNAH7), 64446 (DNAI2), 7802 (DNALI1), 83544 (DNAL1), 8632 (DNAH17), 8701 (DNAH11) 10376 (T... |
PATHWAYS OF NEURODEGENERATION - MULTIPLE DISEASES Endoplasmic reticulum (ER) PrP ER stress CASP... |
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hsa05034
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Alcoholism |
Alcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is pro... |
... (H3C1), 8351 (H3C4), 8352 (H3C3), 8353 (H3C6), 8354 (H3C11), 8355 (H3C8), 8356 (H3C12), 8357 (H3C10... |
ALCOHOLISM Neuron (Presynaptic terminal) Neuron (Postsynaptic cell) VMAT Control Dopaminergic synaps... |
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hsa05131
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Shigellosis |
Shigellosis, or bacillary dysentery, is an intestinal infection caused by Shigella, a genus of enter... |
... (H3C1), 8351 (H3C4), 8352 (H3C3), 8353 (H3C6), 8354 (H3C11), 8355 (H3C8), 8356 (H3C12), 8357 (H3C10... |
SHIGELLOSIS Shigella dysenteria Shigella flexneri Shigella boydii Shigella sonnei TNF-R1 TNFα IκBÎ... |
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hsa05132
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Salmonella infection |
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid ... |
...MO2), 9844 (ELMO1) 338382 (RAB7B), 7879 (RAB7A) 83547 (RILP) 79443 (FYCO1) 140735 (DYNLL2), 1778 (DY... |
SopB AvrA MyD88 MyD88 MyD88 ERK IKKβ TAK1 p38 IRAK1/4 IKKα IL-8 TIRAP MyD88 JNK IL-1β TRAF6 IL-6 ... |
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hsa05202
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Transcriptional misregulation in cancer |
In tumor cells, genes encoding transcription factors (TFs) are often amplified, deleted, rearranged ... |
... (H3C1), 8351 (H3C4), 8352 (H3C3), 8353 (H3C6), 8354 (H3C11), 8355 (H3C8), 8356 (H3C12), 8357 (H3C10... |
TRANSCRIPTIONAL MISREGULATION IN CANCER Ewing's sarcoma Clear-cell sarcoma Desmoplastic small ro... |
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hsa05322
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Systemic lupus erythematosus |
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterised by the productio... |
... (H3C1), 8351 (H3C4), 8352 (H3C3), 8353 (H3C6), 8354 (H3C11), 8355 (H3C8), 8356 (H3C12), 8357 (H3C10... |
BCR FcγR FcγR IgG IgG IgG IgG Elastase Cathepsin C1s C1q C1r MAC TNF-α IFN-γ IL-10 C1q C1q CD80/... |