Pathway Text Search

Number of entries in a page   

Items : 1 - 20 of 20

Entry Thumbnail Image Name Description Object Legend
hsa04012 ErbB signaling pathway ... exploited by others. These include the adaptors Crk, Nck, the phospholipase C gamma (PLCgamma), the... ... 5599 (MAPK8), 5601 (MAPK9), 5602 (MAPK10) 1398 (CRK), 1399 (CRKL) 5747 (PTK2) 6654 (SOS1), 6655 (SO... ...B1 TGFα JNKK Cbl ErbB-4 ErbB-3 NRG3 NRG2 Elk JNK Crk FAK Sos Grb2 Shc PKC CAMK PLCγ HB-EGF NRG1 EPR ...
hsa04062 Chemokine signaling pathway Inflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon... ...NG8) 2885 (GRB2) 9564 (BCAR1) 9844 (ELMO1) 1398 (CRK), 1399 (CRKL) 131890 (GRK7), 156 (GRK2), 157 (G... ...phocyte Macrophage Eosinophil GRB2 p130Cas ELMO1 Crk GRK β-arrestin Receptor internalization ROCK Ja...
hsa05100 Bacterial invasion of epithelial cells Many pathogenic bacteria can invade phagocytic and non-phagocytic cells and colonize them intracellu... ...ACTG1) 1793 (DOCK1) 5829 (PXN) 5747 (PTK2) 1398 (CRK), 1399 (CRKL) 23607 (CD2AP) 110117499 (P3R3URF-... ...in Arp2/3 actin Rho GTPases Dock180 Paxillin FAK Crk CD2AP PI3K Cbl Met dynamin Cas Clathrin WAVE N-...
hsa05200 Pathways in cancer ... (FZD9) 26060 (APPL1) 25 (ABL1), 613 (BCR) 1398 (CRK), 1399 (CRKL) 867 (CBL) 1398 (CRK), 1399 (CRKL)... ...ITGB Dvl ECM ITGA FAK PTEN Frizzled APPL BCR-ABL CRKL CBL CRK PI3K STAT5 Jak EGFR ERBB2 PDGFR IGFR c...
hsa05220 Chronic myeloid leukemia Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of a pluripotent stem cell. T... ...C4), 53358 (SHC3), 6464 (SHC1) 9846 (GAB2) 1398 (CRK), 1399 (CRKL) 867 (CBL) 1398 (CRK), 1399 (CRKL)... ...27 MDM2 IKK Bcl-xl Bad p14 p21 Sos Grb2 Shc Gab2 CRK CBL CRKL PIP MDM2 p53 E2F Smad3 CDK4/6 CyclinD1...
hsa04010 MAPK signaling pathway The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in... ... 5601 (MAPK9), 5602 (MAPK10) 6416 (MAP2K4) 1398 (CRK), 1399 (CRKL) 408 (ARRB1), 409 (ARRB2) 2122 (ME... ...c42/Rac PAK1/2 MEKK2/3 JIP1/2 MLK3 MKK7 JNK MKK4 CrkII ARRB Evi1 HSP72 JunD AP1 NFAT-4 NFAT-2 PPP3C ...
hsa04015 Rap1 signaling pathway Rap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction fo... ..., 5330 (PLCB2), 5331 (PLCB3), 5332 (PLCB4) 1398 (CRK), 1399 (CRKL) 999 (CDH1) 2889 (RAPGEF1) 1499 (C... ...ion of actin cytoskeleton (GAPs) (GEFs) GPCR PLC Crk E-cad C3G cAMP DAG β-cat MAGI PDZ-GEF Vav2 Tiam...
hsa04148 Efferocytosis ...(ITGB5) 4240 (MFGE8) 558 (AXL) 5747 (PTK2) 1398 (CRK), 1399 (CRKL) 9564 (BCAR1) 948 (CD36) 2621 (GAS... ...rization ITGA STAB ITGB MFGE8 Efferocyte AXL FAK CRK Apoptotic cell p130CAS CD36 GAS6 CD47 LRP1 CALR...
hsa04510 Focal adhesion Cell-matrix adhesions play essential roles in important biological processes including cell motility... ...4), 53358 (SHC3), 6464 (SHC1) 9564 (BCAR1) 1398 (CRK), 1399 (CRKL) 2889 (RAPGEF1) 5906 (RAP1A), 5908... ...MEK1 B-Raf Raf-1 Ha-Ras Sos Grb2 RTK Shc p130Cas Crk GRF2 Rap1 DOCK1 JNK c-Jun PAK Rac Vav β-Catenin...
hsa04666 Fc gamma R-mediated phagocytosis Phagocytosis plays an essential role in host-defense mechanisms through the uptake and destruction o... ...RPC5L) 998 (CDC42) 7454 (WAS) 1793 (DOCK1) 1398 (CRK), 1399 (CRKL) 5337 (PLD1), 5338 (PLD2) 5058 (PA... ...70S6K Vav Rac WAVE Arp2/3 Cdc42 WASP PIP DOCK180 CrkII PLD PAK1 VASP LIMK Cofilin PAG3 Pseudopod ext...
hsa04722 Neurotrophin signaling pathway Neurotrophins are a family of trophic factors involved in differentiation and survival of neural cel... ... (RPS6KA1), 6196 (RPS6KA2), 6197 (RPS6KA3) 1398 (CRK), 1399 (CRKL) 2889 (RAPGEF1) 5906 (RAP1A), 5908... ... Synapse formation Axonal guidance Erk1/2 p90RSK Crk C3G Rap1 SH-PTP2 B-Raf Gab1 Bad GSK3β FKHRL1 Iκ...
hsa04810 Regulation of actin cytoskeleton ...1) 2245 (FGD1), 89846 (FGD3) 55970 (GNG12) 1398 (CRK), 1399 (CRKL) 9564 (BCAR1) 5747 (PTK2) 1128 (CH... ...iam1 ERK MEK Raf PI3K Rac1GEF Dock180 FGD1/3 Gβγ CrkII Cas FAK GPCR c-Src ITG FN1 Ras Gα12,13 Sos RT...
hsa04910 Insulin signaling pathway Insulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrat... ...K1), 3099 (HK2), 3101 (HK3), 80201 (HKDC1) 1398 (CRK), 1399 (CRKL) 5584 (PRKCI), 5590 (PRKCZ) 10603 ... ...C-1α CAP Rheb Akt P13K TC10 GSK-3β SREBP-1c GRF2 CrkII aPKC APS GLUT4 PDK1/2 Cbl IRS PIP Flotillin I...
hsa04935 Growth hormone synthesis, secretion and action Growth hormone (GH) is a peptide hormone secreted from the anterior pituitary and plays a critical r... ...(FOS) 3726 (JUNB) 5747 (PTK2) 9564 (BCAR1) 1398 (CRK), 1399 (CRKL) 4214 (MAP3K1) 1432 (MAPK14), 5600... ...TOR GSK3 Igf1 Socs1-3 c-Fos JunB DNA FAK p130Cas CrkII MEKK p38 STAT Cytoskeleton re-organization GH...
hsa05131 Shigellosis Shigellosis, or bacillary dysentery, is an intestinal infection caused by Shigella, a genus of enter... ...), 54874 (FNBP1L) 5879 (RAC1) 1793 (DOCK1) 1398 (CRK), 1399 (CRKL) 2017 (CTTN), 3059 (HCLS1) 6714 (S... ... in proinflammatory gene transcript Rac1 Dock180 Crk Cortactin Src ELMO Cdc42 WAVE Arp2/3 ROCK mDia1...
hsa05135 Yersinia infection Pathogenic Yersinia injects virulent Yersinia outer proteins (Yops) into the host cell through a typ... ...C), 81873 (ARPC5L) 2335 (FN1) 9564 (BCAR1) 1398 (CRK), 1399 (CRKL) 1793 (DOCK1) 23396 (PIP5K1C), 839... ITGB1 Src N-WASP Arp2/3 Fibronectin p130Cas Crk DOCK180 PIP(5)KIα Actin PI(4,5)P PIP -binding protei...
hsa05163 Human cytomegalovirus infection Human cytomegalovirus (HCMV) is an enveloped, double-stranded DNA virus that is a member of beta-her... ...R5) 6387 (CXCL12) 7852 (CXCR4) 5747 (PTK2) 1398 (CRK), 1399 (CRKL) 9564 (BCAR1) 5829 (PXN) 5578 (PRK... ...kocyte chemotaxis CXCL12 CXCR4 US27 cmvIL-10 FAK Crk p130CAS Paxillin PKC PYK2 DAG PLCβ Migration IL...
hsa05170 Human immunodeficiency virus 1 infection Human immunodeficiency virus type 1 (HIV-1) , the causative agent of AIDS (acquired immunodeficiency... ...GNAO1) 7124 (TNF) 7852 (CXCR4) 5747 (PTK2) 1398 (CRK), 1399 (CRKL) 5829 (PXN) 5578 (PRKCA), 5579 (PR... ... of actin cytoskeleton Proteasome TNFα CXCR4 FAK Crk Paxillin PKC PYK2 DAG Chemotaxis Uninfected CD4...
hsa05206 MicroRNAs in cancer MicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, ... ...I) 3845 (KRAS) 1021 (CDK6) 406913 (MIR126) 1398 (CRK), 1399 (CRKL) 406948 (MIR15A), 406949 (MIR15B),... ...dc25 BCL2L2 VEGF-A Cdk6 Let-7 K-Ras Cdk6 miR-126 CRK miR-15/16 miR-107 miR-17-92 miR-29 DNMT3 miR-1 ...
hsa05211 Renal cell carcinoma Renal cell cancer (RCC) accounts for ~3% of human malignancies and its incidence appears to be risin... ... (FLCN) 2271 (FH) 7422 (VEGFA) 5879 (RAC1) 1398 (CRK), 1399 (CRKL) 2889 (RAPGEF1) 6654 (SOS1), 6655 ... ...onginB ElonginC TGF-β TGF-α PDGF-β BHD VEGF Rac1 Crk C3G SOS Grb2 HPH VHL HIF-β p300/CBP HIF-α MET G...

Items : 1 - 20 of 20


[ PATHWAY | KEGG ]