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Entry Thumbnail Image Name Description Object Legend
hsa01521 EGFR tyrosine kinase inhibitor resistance EGFR is a tyrosine kinase that participates in the regulation of cellular homeostasis. EGFR also ser... ...4 (RPS6) 1977 (EIF4E), 253314 (EIF4E1B), 9470 (EIF4E2) 2309 (FOXO3) 10018 (BCL2L11) 7039 (TGFA) 1956... Non-small cell lung cancer Her3 Her2 EGFR Pancreatic cancer mTOR signaling pathway GSK-3 eI...
hsa03013 RNA transport RNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RN... ...(EIF4A2) 1977 (EIF4E), 253314 (EIF4E1B), 9470 (EIF4E2) 1981 (EIF4G1), 1982 (EIF4G2), 8672 (EIF4G3) 1... NPC RNA TRANSPORT Nucleus Cytoplasm pre-tRNA U snRNA pre-mRNA pre-rRNA RanGTP exportin-t Expt Ran ...
hsa04066 HIF-1 signaling pathway Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of... ...IF4EBP1) 1977 (EIF4E), 253314 (EIF4E1B), 9470 (EIF4E2) 6198 (RPS6KB1), 6199 (RPS6KB2) 6194 (RPS6) 55... CUL2 Rbx1 ElonginB ElonginC VEGF PHD VHL HIF-1β p300/CBP HIF-1α Glut1 HIF-1 SIGNALING PATHWAY mT...
hsa04150 mTOR signaling pathway The mammalian (mechanistic) target of rapamycin (mTOR) is a highly conserved serine/threonine protei... ... (DDIT4) 1977 (EIF4E), 253314 (EIF4E1B), 9470 (EIF4E2) 8408 (ULK1), 9706 (ULK2) 6194 (RPS6) 7124 (TN... mTOR SIGNALING PATHWAY IRS1 PI3K Raf MAPK signaling pathway ERK1/2 Ras MEK PTEN PDK1 Akt TSC1/2 Rh...
hsa04151 PI3K-Akt signaling pathway The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellul... ...20 (AMP) 1977 (EIF4E), 253314 (EIF4E1B), 9470 (EIF4E2) 1978 (EIF4EBP1) 6194 (RPS6) 1975 (EIF4B) 6198... PIP eIF4E 4EBPs eIF4B S6K1/2 Raptor mTOR GβL Rheb TSC2 TSC1 AKT PDK1 PI3K p53 signaling pathway mTO...
hsa04211 Longevity regulating pathway Regulation of longevity depends on genetic and environmental factors. Caloric restriction (CR), that... ...IF4EBP1) 1977 (EIF4E), 253314 (EIF4E1B), 9470 (EIF4E2) 6794 (STK11) 7157 (TP53) 143686 (SESN3), 2724... FOXO S6K mTOR Akt P13K PIP LONGEVITY REGULATING PATHWAY DNA IGF-I IGF-IR IRS1-4 Ras cAMP PKA AMPK ...
hsa04910 Insulin signaling pathway Insulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrat... ...3 (NRAS) 1977 (EIF4E), 253314 (EIF4E1B), 9470 (EIF4E2) 5604 (MAP2K1), 5605 (MAP2K2) 25759 (SHC2), 39... TSC1 SKIP SHIP2 IKK JNK LAR PTP1B SOCS Elk1 MNK ERK1/2 FAS AMPK Glycogen cAMP INS Glucose HSL PP1 PY...

Items : 1 - 7 of 7


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