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Thumbnail Image |
Name |
Description |
Object |
Legend |
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hsa05131
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Shigellosis |
Shigellosis, or bacillary dysentery, is an intestinal infection caused by Shigella, a genus of enter... |
...2) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (GABARAPL1) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (... |
SHIGELLOSIS Shigella dysenteria Shigella flexneri Shigella boydii Shigella sonnei TNF-R1 TNFα IκBÎ... |
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hsa04136
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Autophagy - other |
Autophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and... |
...3) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (GABARAPL1) 115201 (ATG4A), 23192 (ATG4B), 84938 (ATG4C... |
AUTOPHAGY - OTHER Nutrient starvation TORC1 complex Raptor TOR LST8 ATG1 complex ATG1 ATG13 ATG11 ... |
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hsa04140
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Autophagy - animal |
Autophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, orga... |
...Q) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (GABARAPL1) 115201 (ATG4A), 23192 (ATG4B), 84938 (ATG4C... |
PI3P AUTOPHAGY - ANIMAL Nutrient starvation (Amino acids, glucose) mTORC1 complex ER stress Fusion... |
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hsa05167
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Kaposi sarcoma-associated herpesvirus infection |
Kaposi sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), is the most... |
...L) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (GABARAPL1) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (... |
IFN-α/β TRAF3 IRF7 IFN-β IFN-α IKK JNK TBK1 IKKε AKT STAT1 IκBα IRF3 TLR3 TRIF KAPOSI SARCO... |
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hsa04068
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FoxO signaling pathway |
The forkhead box O (FOXO) family of transcription factors regulates the expression of genes in cellu... |
...3) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (GABARAPL1) 9140 (ATG12) 100533105 (C8orf44-SGK3), 1011... |
IKKα/β JNK ERK1/2 AMPK INS Glucose FOXO SOS Ras MEK1/2 INSR Raf PEPCK G6PC Akt P13K PDK1/2 IRS PIP... |
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hsa04137
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Mitophagy - animal |
Mitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to gro... |
...1) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (GABARAPL1) 6714 (SRC) 8408 (ULK1) 139341 (FUNDC1) 1457... |
MITOPHAGY - ANIMAL PINK1 Mfn1/2 Depolarization of mitochondria USP30 USP15 AMBRA1 USP8 Parkin Auto... |
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hsa04371
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Apelin signaling pathway |
Apelin is an endogenous peptide capable of binding the apelin receptor (APJ), which was originally d... |
...3) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (GABARAPL1) 441925 (BECN2), 8678 (BECN1) 1958 (EGR1) 66... |
APELIN SIGNALING PATHWAY APJ AMPK Sphk1 PAI-1 Gα βγ PI3K Akt MEK1/2 ERK1/2 P70S6K PLCβ IP3 IP3... |
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hsa04621
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NOD-like receptor signaling pathway |
Specific families of pattern recognition receptors are responsible for detecting various pathogens a... |
...1) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (GABARAPL1) 4790 (NFKB1), 5970 (RELA) 9140 (ATG12) 9474... |
ASC pro-CASP1 ASC pro-CASP1 ASC pro-CASP1 ASC pro-CASP1 NOD1 NOD2 iE-DAP RIP2 IKKα/β TAK1 TAB NLRP... |
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hsa04727
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GABAergic synapse |
Gamma aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in the mammalian cen... |
...Q) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (GABARAPL1) 4905 (NSF) 2554 (GABRA1), 2555 (GABRA2), 25... |
GABAERGIC SYNAPSE Glial cell Neuron (Presynaptic terminal) Neuron (Postsynaptic cell) GABA GAT2/3 V... |
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hsa05014
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Amyotrophic lateral sclerosis |
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by a progressive d... |
...1) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (GABARAPL1) 7416 (VDAC1) 596 (BCL2) 23435 (TARDBP) 2343... |
SOD1 EAAT2 AMYOTROPHIC LATERAL SCLEROSIS Motor neuron Astrocyte Presynaptic neuron Microglial cell... |
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hsa05022
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Pathways of neurodegeneration - multiple diseases |
Neurodegeneration is generally defined as progressive, irreversible loss of neurons, which may affec... |
...N) 11337 (GABARAP), 11345 (GABARAPL2), 23710 (GABARAPL1) 7416 (VDAC1) 596 (BCL2) 23435 (TARDBP) 9896... |
PATHWAYS OF NEURODEGENERATION - MULTIPLE DISEASES Endoplasmic reticulum (ER) PrP ER stress CASP... |