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Entry Thumbnail Image Name Description Object Legend
hsa04933 AGE-RAGE signaling pathway in diabetic complications Advanced glycation end products (AGEs) are a complex group of compounds produced through the non-enz... ...SMAD3) 4089 (SMAD4) 1906 (EDN1) 2152 (F3) 7056 (THBD) 3552 (IL1A), 3553 (IL1B) 3569 (IL6) 7124 (TNF)... ...K1/2 TGF-β TGFβRI TGFβRII Smad2/3 Smad4 END1 THBD IL-1 IL-6 TNF-α VCAM-1 ICAM-1 IL-8 AP-1 JAK2 S...
hsa04610 Complement and coagulation cascades The complement system is a proteolytic cascade in blood plasma and a mediator of innate immunity, a ... ...PA), 725 (C4BPB) 5627 (PROS1) 5624 (PROC) 7056 (THBD) 5265 (SERPINA1) 2147 (F2) 2 (A2M) 5345 (SERPIN... COMPLEMENT AND COAGULATION CASCADES Coagulation cascade F12 F11 F10 Fibrin monomer Fibrinogen F1...
hsa05418 Fluid shear stress and atherosclerosis Shear stress represents the frictional force that the flow of blood exerts at the endothelial surfac... ...(NOS3) 4880 (NPPC) 445 (ASS1) 4846 (NOS3) 7056 (THBD) 5327 (PLAT) 4846 (NOS3) 1499 (CTNNB1) 4313 (MM... FLUID SHEAR STRESS AND ATHEROSCLEROSIS ONOO MAPK signaling pathway p38 VCAM-1 ICAM-1 AP-1 Akt P...

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