Entry |
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Name |
Description |
Object |
Legend |
hsa04137
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Mitophagy - animal |
Mitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to gro... |
... 51024 (FIS1) 5868 (RAB5A), 5869 (RAB5B), 5878 (RAB5C) 5868 (RAB5A), 5869 (RAB5B), 5878 (RAB5C) 3383... |
MITOPHAGY - ANIMAL PINK1 Parkin OPTN TBK1 P62 NDP52 NBR1 TAX1BP1 ARIH1 SIAH1 HUWE1 GP78 MUL1 SMURF... |
hsa04144
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Endocytosis |
Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins... |
...) 9101 (USP8) 5868 (RAB5A), 5869 (RAB5B), 5878 (RAB5C) 382 (ARF6) 10617 (STAMBP) 26119 (LDLRAP1) 160... |
ENDOCYTOSIS STAM Hrs PI(3)P PI(3)P ESCRT-I ESCRT-0 ESCRT-II ESCRT-III Late endosome and multivesicul... |
hsa05152
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Tuberculosis |
Tuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the... |
...) 3586 (IL10) 5868 (RAB5A), 5869 (RAB5B), 5878 (RAB5C) 5289 (PIK3C3) 10312 (TCIRG1), 23545 (ATP6V0A2... |
SapM TUBERCULOSIS DC-SIGN Raf1 IL-10 Pro-inflammatory cytokines Phagosome maturation arrest Rab5 VPS... |
hsa04014
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Ras signaling pathway |
The Ras proteins are GTPases that function as molecular switches for signaling pathways regulating c... |
..., 2114 (ETS2) 5868 (RAB5A), 5869 (RAB5B), 5878 (RAB5C) 22800 (RRAS2), 22808 (MRAS), 3265 (HRAS), 384... |
MAPK signaling pathway RAS SIGNALING PATHWAY ERK MEK Raf-1 Ras PI3K-Akt signaling pathway Grb2 SOS... |
hsa04145
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Phagosome |
Phagocytosis is the process of taking in relatively large particles by a cell, and is a central mech... |
...) 8411 (EEA1) 5868 (RAB5A), 5869 (RAB5B), 5878 (RAB5C) 338382 (RAB7B), 7879 (RAB7A) 1536 (CYBB) 8354... |
PHAGOSOME Fc gamma R-mediated phagocytosis Endocytosis Phagocytic cup pathogen Conventional p... |
hsa04148
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Efferocytosis |
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...1) 19 (ABCA1) 5868 (RAB5A), 5869 (RAB5B), 5878 (RAB5C) 64284 (RAB17) 23355 (VPS8), 55823 (VPS11), 57... |
ADGRB1 MERTK DOCK1 Rac1 GULP1 ELMO Actin polymerization ITGA STAB ITGB MFGE8 Efferocyte AXL FAK CRK ... |
hsa04962
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Vasopressin-regulated water reabsorption |
In the kidney, the antidiuretic hormone vasopressin (AVP) is a critical regulator of water homeostas... |
...9230 (RAB11B) 5868 (RAB5A), 5869 (RAB5B), 5878 (RAB5C) 6810 (STX4) 6844 (VAMP2) 4905 (NSF) 10540 (DC... |
VASOPRESSIN-REGULATED WATER REABSORPTION Renal interstitium fluid (blood) DNA Urinary lumen Nucleu... |
hsa05132
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Salmonella infection |
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid ... |
...5082 (VPS33A) 5868 (RAB5A), 5869 (RAB5B), 5878 (RAB5C) 5289 (PIK3C3) 23207 (PLEKHM2) 8677 (STX10) 96... |
SopB AvrA MyD88 MyD88 MyD88 ERK IKKβ TAK1 p38 IRAK1/4 IKKα IL-8 TIRAP MyD88 JNK IL-1β TRAF6 IL-6 TAB... |
hsa05146
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Amoebiasis |
Entamoeba histolytica, an extracellular protozoan parasite is a human pathogen that invades the inte... |
...8382 (RAB7B), 5868 (RAB5A), 5869 (RAB5B), 5878 (RAB5C), 7879 (RAB7A) 3315 (HSPB1) 7097 (TLR2) 909 (C... |
Extracellular matrix Intestinal epithelial cell Entamoeba histolytica trophozoite IL1β MUC2 Laminin... |