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Entry Thumbnail Image Name Description Object Legend
hsa04218 Cellular senescence ...h as telomere shortening, oncogene activation, irradiation, DNA damage and oxidative stress. It is c... C16844 (Hydroxyl radical), C00027 (Hydrogen peroxide) C07909 (Sirolimus) C00076 (Calcium cation) C16... CELLULAR SENESCENCE NORE1A PP1A C-Myc HIPK2 ARF MDM2 p53 P53 signaling pathway PI3K AKT TSC1/2 RHEB...
hsa04010 MAPK signaling pathway The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in... C00338 (Lipopolysaccharide) C00165 (Diacylglycerol) C00575 (3',5'-Cyclic AMP) C01245 (D-myo-Inositol... ...meric G-protein Serum, cytotoxic drugs, irradiation, heatshock, reactive oxygen species, ...
hsa04115 p53 signaling pathway p53 activation is induced by a number of stress signals, including DNA damage, oxidative stress and ... 6477 (SIAH1) 3486 (IGFBP3) 10912 (GADD45G), 1647 (GADD45A), 4616 (GADD45B) 4194 (MDM4) 1111 (CHEK1) ... ...G PATHWAY Cell cycle Siah P53AIP PUMA Noxa γ-irradiation Genotoxic drugs Nutrition deprivation Hea...
hsa05332 Graft-versus-host disease Graft-versus-host disease (GVHD) is a lethal complication of allogeneic hematopoietic stem cell tran... C00533 (Nitric oxide) C00338 (Lipopolysaccharide) 3108 (HLA-DMA), 3109 (HLA-DMB), 3111 (HLA-DOA), 31... ...d donor Th1 cell Donor NK (chemotherapy and/or irradiation) Endotoxin enters circulation Tissue dama...

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