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Name |
Description |
Object |
Legend |
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hsa04110
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Cell cycle |
Mitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replic... |
...) 4193 (MDM2) 1387 (CREBBP), 2033 (EP300) 6502 (SKP2) 9088 (PKMYT1) 494551 (WEE2), 7465 (WEE1) 10744... |
...4 14-3-3 14-3-3σ Chk1, 2 Cip1 DNA-PK Mdm2 p300 Skp2 Myt1 Wee PTTG Esp1 Smc1 Apoptosis Skp2 GADD45 p... |
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hsa05169
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Epstein-Barr virus infection |
Epstein-Barr virus (EBV) is a gamma-herpes virus that widely infects human populations predominantly... |
... 3065 (HDAC1), 3066 (HDAC2) 1027 (CDKN1B) 6502 (SKP2) 5925 (RB1) 7874 (USP7) 7157 (TP53) 8717 (TRADD... |
...ion of latent infection CD21 HDAC1/2 EBNA3C p27 Skp2 EBNA1 USP7 p53 Cell proliferation LMP1 TRADD RI... |
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hsa04068
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FoxO signaling pathway |
The forkhead box O (FOXO) family of transcription factors regulates the expression of genes in cellu... |
...(GRB2) 6789 (STK4) 1950 (EGF) 5728 (PTEN) 6502 (SKP2) 4193 (MDM2) 1387 (CREBBP), 2033 (EP300) 23411 ... |
...b2 ROS MST1 EGF PI3K-Akt signaling pathway PTEN SKP2 Ubiquitination MDM2 CBP SIRT1 IGF1 IGF1R FOXO U... |
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hsa04150
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mTOR signaling pathway |
The mammalian (mechanistic) target of rapamycin (mTOR) is a highly conserved serine/threonine protei... |
...31 (NPRL3), 9681 (DEPDC5) 220441 (RNF152) 6502 (SKP2) 54468 (MIOS), 6396 (SEC13), 79726 (WDR59), 819... |
... IKKβ TNFR S6K SLC7A5 SLC3A2 SOS GATOR1 RNF152 Skp2 GATOR2 SESN2 Leu V-ATPase SLC38A9 Ragulator Lys... |
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hsa05200
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Pathways in cancer |
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...F3) 1017 (CDK2) 898 (CCNE1), 9134 (CCNE2) 6502 (SKP2) 1163 (CKS1B), 1164 (CKS2) 890 (CCNA2), 8900 (C... |
...yc Max Miz1 CyclinD p21 CDK4/6 E2F CDK2 CyclinE Skp2 CKS1 CyclinA1 Tissue invasion & metastasis Ev... |
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hsa05203
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Viral carcinogenesis |
There is a strong association between viruses and the development of human malignancies. We now know... |
... 7532 (YWHAG), 7533 (YWHAH), 7534 (YWHAZ) 6502 (SKP2) 11317 (RBPJL), 3516 (RBPJ) 22938 (SNW1) 2965 (... |
...ion Induction of FasL Mitochondrial dysfunction Skp2 RBP-Jκ SKIP TFIIH TFIIE p100 p300/CBP TFIIB Tr... |
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hsa05222
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Small cell lung cancer |
Lung cancer is a leading cause of cancer death among men and women in industrialized countries. Smal... |
...DK6) 4790 (NFKB1), 5970 (RELA) 5925 (RB1) 6502 (SKP2) 1030 (CDKN2B) 581 (BAX) 836 (CASP3) 7157 (TP53... |
...COX-2 IKK IκBα Bcl-XL TRAFs E2F CDK4/6 NF-κB Skp2 p15 INK4b Kip1 Neuroendocrine epithelial cells ... |
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hsa04120
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Ubiquitin mediated proteolysis |
Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions... |
...32 (FBXO2), 26272 (FBXO4), 55294 (FBXW7), 6502 (SKP2), 8945 (BTRC) 23221 (RHOBTB2), 55958 (KLHL9), 9... |
UBLE1B UBLE1A EloC EloB RBX1 RBX1 RBX1 RBX1 F-box BTB DCAF SOCSbox VHLbox HERC4 HERC3 UBE2W UBE2F UB... |