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Items : 1 - 14 of 14

Entry Thumbnail Image Name Description Object Legend
hsa04662 B cell receptor signaling pathway B cells are an important component of adaptive immunity. They produce and secrete millions of differ... ...) 5579 (PRKCB) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 5290 (PIK3CA), 5291 (PIK3CB), 5293 (PIK3CD), 5... PIP DAG IκB NFκB IKKβ IKKγ IKKα GSK3β MALT1 BCL-10 CARMA1 AKT PKCβ VAV PI3K CD21 CD19 CD81 LE...
hsa04670 Leukocyte transendothelial migration Leukocyte migaration from the blood into tissues is vital for immune surveillance and inflammation. ... ..., 5908 (RAP1B) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 3684 (ITGAM) 3683 (ITGAL) 5879 (RAC1) 5880 (RA... CAMs MMPs CAMs SHP-2 CDH5 CD99 PECAM1 ITGB2 p120ctn p130 AF-6 SPA-1 PECAM1 JAM1 ITGAL CDH5 SHP-2 CD9...
hsa04015 Rap1 signaling pathway Rap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction fo... ...9693 (RAPGEF2) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 7074 (TIAM1) 5879 (RAC1), 5880 (RAC2), 5881 (R... ... PLC Crk E-cad C3G cAMP DAG β-cat MAGI PDZ-GEF Vav2 Tiam Rac PAR3 Arap3 Rho PKD1 Krit Src FRG Cdc42...
hsa04024 cAMP signaling pathway cAMP is one of the most common and universal second messengers, and its formation is promoted by ade... ...) 7074 (TIAM1) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 5879 (RAC1), 5880 (RAC2), 5881 (RAC3) 5058 (PA... ...elial cell, smooth muscle cell) Apoptosis Tiam1 Vav2 Rac PAK1 Cytoskeletal remodelling, adherens jun...
hsa05205 Proteoglycans in cancer Many proteoglycans (PGs) in the tumor microenvironment have been shown to be key macromolecules that... ...C) 2885 (GRB2) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 5879 (RAC1) 9138 (ARHGEF1) 387 (RHOA) 960 (CD4... ...Oncogenic signaling CD44 c-Src Lipid Raft Grb2 Vav2 Rac1 Cytoskeleton activation p115 RhoA (Head an...
hsa04062 Chemokine signaling pathway Inflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon... ..., 9475 (ROCK2) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 3702 (ITK) 998 (CDC42) 107 (ADCY1), 108 (ADCY2... Migration Apoptosis Degranulation Cellular shape changes Cell survival chemokineR chemokine JAK2/3 ...
hsa04510 Focal adhesion Cell-matrix adhesions play essential roles in important biological processes including cell motility... ...), 5881 (RAC3) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 1499 (CTNNB1) 2932 (GSK3B) 60 (ACTB), 71 (ACTG... ECM-receptor interaction Cytokine-cytokine receptor interaction MAPK signaling pathway ITGB ITGA Fil...
hsa04650 Natural killer cell mediated cytotoxicity Natural killer (NK) cells are lymphocytes of the innate immune system that are involved in early def... ...), 5881 (RAC3) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 356 (FASLG) 3002 (GZMB) 5551 (PRF1) 3824 (KLRD... IgG NFAT CaN PI(3,4,5)P Fyn TRAIL IFNγR PLCγ LAT Perforin HLA-E IFN-γ GM-CSF TNF-α PKC 3BP2 PLC...
hsa04660 T cell receptor signaling pathway Activation of T lymphocytes is a key event for an efficient response of the immune system. It requir... ...) 9402 (GRAP2) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 387 (RHOA), 998 (CDC42) 10298 (PAK4), 10682173... PIP DAG CDK4 TNFα GM-CSF IFN-γ IL-10 IL-5 IL-4 IL-2 IκB NFκB IKKβ IKKγ IKKα NIK COT AKT MALT1...
hsa04664 Fc epsilon RI signaling pathway Fc epsilon RI-mediated signaling pathways in mast cells are initiated by the interaction of antigen ... ...), 5881 (RAC3) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 3567 (IL5) 3562 (IL3) 240 (ALOX5) 241 (ALOX5AP... IgE IgE FcεRIγ FcεRIβ FcεRIα PGD LTE LTD LTC Arachidonic acid Heparin Histamine DAG FcεRIβ F...
hsa04666 Fc gamma R-mediated phagocytosis Phagocytosis plays an essential role in host-defense mechanisms through the uptake and destruction o... ...6199 (RPS6KB2) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 5879 (RAC1), 5880 (RAC2) 10163 (WASF2), 10810 ... Macrophage Monocyte Neutrophil FcγRIIIA FcγRIIB FcγRIIA FcγRI Src Syk CD45 IgG PI3K SHIP LAT PIP...
hsa04810 Regulation of actin cytoskeleton ... 10451 (VAV3), 7074 (TIAM1), 7409 (VAV1), 7410 (VAV2) 5594 (MAPK1), 5595 (MAPK3) 5604 (MAP2K1), 5605... PIP PIP PIP Acetylcholine TMSB4 Arp2/3 PFN WAVE2 WAVE1 HSPC300 APC NWASP Asef Abi2 Nap125 PIR121 IRS...
hsa05135 Yersinia infection Pathogenic Yersinia injects virulent Yersinia outer proteins (Yops) into the host cell through a typ... ...2) 3586 (IL10) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 2353 (FOS), 3725 (JUN) 5879 (RAC1) 3551 (IKBKB... ITGB1 Src N-WASP Arp2/3 Fibronectin p130Cas Crk DOCK180 PIP(5)KIα Actin PI(4,5)P PIP -binding prote...
hsa05417 Lipid and atherosclerosis Atherosclerosis is a chronic inflammatory disease marked by a narrowing of the arteries from lipid-r... ...N) 5747 (PTK2) 10451 (VAV3), 7409 (VAV1), 7410 (VAV2) 5468 (PPARG) 6256 (RXRA), 6257 (RXRB), 6258 (R... PIP AKT PDK1 PI3K p53 signaling pathway LIPID AND ATHEROSCLEROSIS GSK3β p53 Apoptosis Apoptosis F...

Items : 1 - 14 of 14


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