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map00563
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Glycosylphosphatidylinositol (GPI)-anchor biosynthesis |
...ycolipid structure called glycosylphosphatidylinositol (GPI) anchor. Hundreds of GPI-anchored protei... |
...13150 G12396 (6-(alpha-D-glucosaminyl)-1D-myo-inositol) G00145 G00143 G00144 G00146 G13151 G13128 C0... |
...PIG-U PIG-T PIG-S 6-(α-D-Glucosaminyl)-1D-myo-inositol PIG-M Phosphatidyl-ethanolamine PIG-F PIG-L P... |
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map00562
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Inositol phosphate metabolism |
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C11557 (1-Phosphatidyl-1D-myo-inositol 5-phosphate) C11555 (1D-myo-Inositol 1,4,5,6-tetrakisphosphat... |
1-Phosphatidyl-1D-myo-inositol-5P 2.7.1.149 1D-myo-Inositol- 1,4,5,6P 3.1.3.36 2.7.1.151 2.7.1.151 3... |
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map04070
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Phosphatidylinositol signaling system |
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C11554 (1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate) C11556 (1-Phosphatidyl-1D-myo-inositol 3,5-... |
... PI(3)P PI(3,4,5)P PI(4)P Phosphatidyl-1D-myo-inositol (PI) CALM IP3R 2.7.8.11 PIK3C PIP5K PIKFYVE P... |
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map00571
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Lipoarabinomannan (LAM) biosynthesis |
...rally related lipomannan (LM) and phosphatidylinositol mannosides (PIMs), are major glycolipids foun... |
C01194 (1-Phosphatidyl-D-myo-inositol) G11291 (Phosphatidyl-myo-inositol monomannoside) G13108 (Tria... |
...an CapA CapA CapA Man Man Man Man Phospho-myo-inositol cap of PILAM Ino-P PPM MptC MptC MptC No cap ... |
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map04151
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PI3K-Akt signaling pathway |
The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellul... |
C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00533 (Nitric oxide) C04637 (1-Phosphatidyl-D-myo... |
PIP eIF4E 4EBPs eIF4B S6K1/2 Raptor mTOR GβL Rheb TSC2 TSC1 AKT PDK1 PI3K p53 signaling pathway mTOR... |
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map00521
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Streptomycin biosynthesis |
...The streptidine moiety is synthesized via myo-inositol, which is then oxidized at C-1 and transamina... |
C01214 (1-Amino-1-deoxy-scyllo-inositol) C03319 (dTDP-L-rhamnose) C06592 (NDP-N-methyl-L-glucosamine... |
...ose-6P Streptidine-6P scyllo-Inosamine-4P myo-Inositol 1L-myo-Inositol-1P 2.7.1.72 3.1.3.39 5.1.3.13... |
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map04072
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Phospholipase D signaling pathway |
...amilies and the phosphoinositide, phosphatidylinositol 4,5-bisphosphate (PIP2). The PLD-produced PA ... |
C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00165 (Diacylglycerol) C01245 (D-myo-Inositol 1,4... |
MAPK signaling pathway PHOSPHOLIPASE D SIGNALING PATHWAY ERK MEK Raf-1 Ras PI3K-Akt signaling pat... |
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map04014
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Ras signaling pathway |
... through effectors including Raf, phosphatidylinositol 3-kinase (PI3K) and Ral guanine nucleotide-di... |
C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00165 (Diacylglycerol) C01245 (D-myo-Inositol 1,4... |
MAPK signaling pathway RAS SIGNALING PATHWAY ERK MEK Raf-1 Ras PI3K-Akt signaling pathway Grb2 SOS... |
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map05225
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Hepatocellular carcinoma |
...n pathway (CTNNB1 and AXIN1), the phosphatidylinositol-3 kinase (PI3K)/AKT/mammalian target of rapam... |
C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) ... |
HEPATOCELLULAR CARCINOMA EGFR Ras Raf MEK ERK1/2 Shc Grb2 SOS mTOR S6K IGF-II IGF1R PI3K-Akt signal... |
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map04020
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Calcium signaling pathway |
...smic/sarcoplasmic reticulum (ER/SR), in which inositol-1,4,5-trisphosphate receptors (IP3Rs) or ryan... |
...2 (ATP) C00165 (Diacylglycerol) C01245 (D-myo-Inositol 1,4,5-trisphosphate) C00575 (3',5'-Cyclic AMP... |
...depression Long term potentiation Phosphatidylinositol signaling pathway Apoptosis MAPK si... |
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map04012
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ErbB signaling pathway |
...ll ErbB receptors. Similarly, the phosphatidylinositol-3-kinase (PI-3K) pathway is directly or indir... |
...cation) C00165 (Diacylglycerol) C01245 (D-myo-Inositol 1,4,5-trisphosphate) C05981 (Phosphatidylinos... |
Non-small cell lung cancer Grb2 Elk ErbB-4 ErbB-4 ErbB-3 ErbB-3 STAT5 ErbB-2 ErbB-2 ErbB-2 ErbB-2... |
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map04370
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VEGF signaling pathway |
...growth, whereas activation of the phosphatidylinositol 3' -kinase (PI3K)-Akt pathway leads to increa... |
... oxide) C00076 (Calcium cation) C01245 (D-myo-Inositol 1,4,5-trisphosphate) C00165 (Diacylglycerol) ... |
Cdc42 DAG Calcium signaling pathway Focal adhesion MAPK signaling pathway VEGFR2 PLCγ SPK PIP PGI CO... |
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map04662
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B cell receptor signaling pathway |
...family kinase BTK- are activated. Phosphatidylinositol 3-kinase (PI3K) and phospholipase C-gamma 2 (... |
C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00165 (Diacylglycerol) C00076 (Calcium cation) C0... |
PIP DAG IκB NFκB IKKβ IKKγ IKKα GSK3β MALT1 BCL-10 CARMA1 AKT PKCβ VAV PI3K CD21 CD19 CD81 LEU13 SHI... |
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map04725
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Cholinergic synapse |
...lter cellular homeostasis of phospholipase C, inositol trisphosphate, cAMP, and free calcium. In the... |
...line) C00575 (3',5'-Cyclic AMP) C01245 (D-myo-Inositol 1,4,5-trisphosphate) C00165 (Diacylglycerol) ... |
CHOLINERGIC SYNAPSE Neuron (Presynaptic terminal) Neuron (Postsynaptic cell) nAChR AChE vAChT AcCoA... |
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map04917
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Prolactin signaling pathway |
...t, the major cascade, Src kinase, phosphatidylinositol-3-kinase (PI3K)/AKT, and mitogen-activated pr... |
C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) ... |
Jak_STAT signaling pathway MAPK signaling pathway PIP Akt/PKB PI3K PROLACTIN SIGNALING PATHWAY ERK... |
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map04919
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Thyroid hormone signaling pathway |
...e binds only T3 and activates the phosphatidylinositol 3-kinase (PI3K) pathway. The other binding si... |
C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C02465 (Triiodothyronine) C01829 (Thyroxine) C0246... |
MAPK signaling pathway ITGB ITGA PIP Akt/PKB PDK1 PI3K PKC THYROID HORMONE SIGNALING PATHWAY Regu... |
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map04068
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FoxO signaling pathway |
...kinase B (Akt/PKB), downstream of phosphatidylinositol 3-kinase (PI3K), in response to insulin or se... |
C00031 (D-Glucose) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00008 (ADP) C00020 (AMP) C0002... |
IKKα/β JNK ERK1/2 AMPK INS Glucose FOXO SOS Ras MEK1/2 INSR Raf PEPCK G6PC Akt P13K PDK1/2 IRS PIP F... |
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map04912
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GnRH signaling pathway |
...nsmits its signal to diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG activates the ... |
...donate) C00165 (Diacylglycerol) C01245 (D-myo-Inositol 1,4,5-trisphosphate) C00076 (Calcium cation) ... |
PKC αGSU LHβ PA, PE DAG PLCβ CDC42 cAMP CREB CaMK MKK3/6 p38MAPK MEKK BMK PLA2 IP3R CaM q/11 MT1 GnR... |
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map05120
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Epithelial cell signaling in Helicobacter pylori infection |
... binds to lipid rafts and glycosylphosphatidylinositol-anchored proteins (GPI-APs) of the target cel... |
C01342 (NH4+) C00080 (H+) C00014 (Ammonia) G00263 (Lewis b antigen) C00698 (Cl-) C00086 (Urea) G0024... |
HopZ AlpB AlpA VacA p38 AP-1 JNK MKK4 IKKα IKKγ IKKβ IκBα ATPeV CASP3 PAK1 NF-κB RANTES GRO-α IL-8 C... |
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map01100
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Metabolic pathways |
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...13044 G12396 (6-(alpha-D-glucosaminyl)-1D-myo-inositol) G00032 G00403 (iGb3-Cer) G00392 (iGb4-Cer) G... |
...ycan biosynthesis - heparan sulfate / heparin Inositol phosphate metabolism Fructose and mannose met... |