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Entry Thumbnail Image Name Description Object Legend
map00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis ...ycolipid structure called glycosylphosphatidylinositol (GPI) anchor. Hundreds of GPI-anchored protei... ...13150 G12396 (6-(alpha-D-glucosaminyl)-1D-myo-inositol) G00145 G00143 G00144 G00146 G13151 G13128 C0... ...IG-U PIG-T PIG-S 6-(α-D-Glucosaminyl)-1D-myo-inositol PIG-M Phosphatidyl-ethanolamine PIG-F PIG-L P...
map00562 Inositol phosphate metabolism C11557 (1-Phosphatidyl-1D-myo-inositol 5-phosphate) C11555 (1D-myo-Inositol 1,4,5,6-tetrakisphosphat... 1-Phosphatidyl-1D-myo-inositol-5P 2.7.1.149 1D-myo-Inositol- 1,4,5,6P 3.1.3.36 2.7.1.151 2.7.1.151 3...
map04070 Phosphatidylinositol signaling system C11554 (1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate) C11556 (1-Phosphatidyl-1D-myo-inositol 3,5-... ... PI(3)P PI(3,4,5)P PI(4)P Phosphatidyl-1D-myo-inositol (PI) CALM IP3R 2.7.8.11 PIK3C PIP5K PIKFYVE P...
map00571 Lipoarabinomannan (LAM) biosynthesis ...rally related lipomannan (LM) and phosphatidylinositol mannosides (PIMs), are major glycolipids foun... C01194 (1-Phosphatidyl-D-myo-inositol) G11291 (Phosphatidyl-myo-inositol monomannoside) G13108 (Tria... ...A Man α1 Man α1 Man α1 Man α1 Phospho-myo-inositol cap of PILAM Ino-P PPM MptC MptC MptC No cap ...
map04151 PI3K-Akt signaling pathway The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellul... C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00533 (Nitric oxide) C04637 (1-Phosphatidyl-D-myo... PIP eIF4E 4EBPs eIF4B S6K1/2 Raptor mTOR GβL Rheb TSC2 TSC1 AKT PDK1 PI3K p53 signaling pathway mTO...
map00521 Streptomycin biosynthesis ...The streptidine moiety is synthesized via myo-inositol, which is then oxidized at C-1 and transamina... C01214 (1-Amino-1-deoxy-scyllo-inositol) C03319 (dTDP-L-rhamnose) C06592 (NDP-N-methyl-L-glucosamine... ...ose-6P Streptidine-6P scyllo-Inosamine-4P myo-Inositol 1L-myo-Inositol-1P 2.7.1.72 3.1.3.39 5.1.3.13...
map04072 Phospholipase D signaling pathway ...amilies and the phosphoinositide, phosphatidylinositol 4,5-bisphosphate (PIP2). The PLD-produced PA ... C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00165 (Diacylglycerol) C01245 (D-myo-Inositol 1,4... MAPK signaling pathway PHOSPHOLIPASE D SIGNALING PATHWAY ERK MEK Raf-1 Ras PI3K-Akt signaling pat...
map04020 Calcium signaling pathway ...smic/sarcoplasmic reticulum (ER/SR), in which inositol-1,4,5-trisphosphate receptors (IP3Rs) or ryan... ...2 (ATP) C00165 (Diacylglycerol) C01245 (D-myo-Inositol 1,4,5-trisphosphate) C00575 (3',5'-Cyclic AMP... ...depression Long term potentiation Phosphatidylinositol signaling pathway Apoptosis MAPK si...
map04014 Ras signaling pathway ... through effectors including Raf, phosphatidylinositol 3-kinase (PI3K) and Ral guanine nucleotide-di... C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00165 (Diacylglycerol) C01245 (D-myo-Inositol 1,4... MAPK signaling pathway RAS SIGNALING PATHWAY ERK MEK Raf-1 Ras PI3K-Akt signaling pathway Grb2 SOS...
map05225 Hepatocellular carcinoma ...n pathway (CTNNB1 and AXIN1), the phosphatidylinositol-3 kinase (PI3K)/AKT/mammalian target of rapam... C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) ... HEPATOCELLULAR CARCINOMA EGFR Ras Raf MEK ERK1/2 Shc Grb2 SOS mTOR S6K IGF-II IGF1R PI3K-Akt signal...
map04012 ErbB signaling pathway ...ll ErbB receptors. Similarly, the phosphatidylinositol-3-kinase (PI-3K) pathway is directly or indir... ...cation) C00165 (Diacylglycerol) C01245 (D-myo-Inositol 1,4,5-trisphosphate) C05981 (Phosphatidylinos... Non-small cell lung cancer Grb2 Elk ErbB-4 ErbB-4 ErbB-3 ErbB-3 STAT5 ErbB-2 ErbB-2 ErbB-2 ErbB-2...
map04370 VEGF signaling pathway ...growth, whereas activation of the phosphatidylinositol 3' -kinase (PI3K)-Akt pathway leads to increa... ... oxide) C00076 (Calcium cation) C01245 (D-myo-Inositol 1,4,5-trisphosphate) C00165 (Diacylglycerol) ... Cdc42 DAG Calcium signaling pathway Focal adhesion MAPK signaling pathway VEGFR2 PLCγ SPK PIP PGI C...
map04662 B cell receptor signaling pathway ...family kinase BTK- are activated. Phosphatidylinositol 3-kinase (PI3K) and phospholipase C-gamma 2 (... C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00165 (Diacylglycerol) C00076 (Calcium cation) C0... PIP DAG IκB NFκB IKKβ IKKγ IKKα GSK3β MALT1 BCL-10 CARMA1 AKT PKCβ VAV PI3K CD21 CD19 CD81 LE...
map04725 Cholinergic synapse ...lter cellular homeostasis of phospholipase C, inositol trisphosphate, cAMP, and free calcium. In the... ...line) C00575 (3',5'-Cyclic AMP) C01245 (D-myo-Inositol 1,4,5-trisphosphate) C00165 (Diacylglycerol) ... CHOLINERGIC SYNAPSE Neuron (Presynaptic terminal) Neuron (Postsynaptic cell) nAChR AChE vAChT AcCoA...
map04917 Prolactin signaling pathway ...t, the major cascade, Src kinase, phosphatidylinositol-3-kinase (PI3K)/AKT, and mitogen-activated pr... C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) ... Jak_STAT signaling pathway MAPK signaling pathway PIP Akt/PKB PI3K PROLACTIN SIGNALING PATHWAY ERK...
map04919 Thyroid hormone signaling pathway ...e binds only T3 and activates the phosphatidylinositol 3-kinase (PI3K) pathway. The other binding si... C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C02465 (Triiodothyronine) C01829 (Thyroxine) C0246... MAPK signaling pathway ITGB ITGA PIP Akt/PKB PDK1 PI3K PKC THYROID HORMONE SIGNALING PATHWAY Regu...
map04068 FoxO signaling pathway ...kinase B (Akt/PKB), downstream of phosphatidylinositol 3-kinase (PI3K), in response to insulin or se... C00031 (D-Glucose) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00008 (ADP) C00020 (AMP) C0002... IKKα/β JNK ERK1/2 AMPK INS Glucose FOXO SOS Ras MEK1/2 INSR Raf PEPCK G6PC Akt P13K PDK1/2 IRS PIP...
map04912 GnRH signaling pathway ...nsmits its signal to diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG activates the ... ...donate) C00165 (Diacylglycerol) C01245 (D-myo-Inositol 1,4,5-trisphosphate) C00076 (Calcium cation) ... PKC αGSU LHβ PA, PE DAG PLCβ CDC42 cAMP CREB CaMK MKK3/6 p38MAPK MEKK BMK PLA2 IP3R CaM q/11 MT1 ...
map05120 Epithelial cell signaling in Helicobacter pylori infection ... binds to lipid rafts and glycosylphosphatidylinositol-anchored proteins (GPI-APs) of the target cel... C01342 (NH4+) C00080 (H+) C00014 (Ammonia) G00263 (IV2Fuc,III4Fuc-Lc4-Cer) C00698 (Cl-) C00086 (Urea... HopZ AlpB AlpA VacA p38 AP-1 JNK MKK4 IKKα IKKγ IKKβ IκBα ATPeV CASP3 PAK1 NF-κB RANTES GRO-α...
map01100 Metabolic pathways ...13044 G12396 (6-(alpha-D-glucosaminyl)-1D-myo-inositol) G00032 G00403 (iGb3-Cer) G00392 (iGb4-Cer) G... ...ycan biosynthesis - heparan sulfate / heparin Inositol phosphate metabolism Fructose and mannose met...

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