KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:apre00010 apre01200 apre01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:apre00010 apre01200 apre01230 apre01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:apre00010 apre00020 apre01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:apre00010 apre00020 apre00620 apre00785 apre01200 apre01210 apre01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:apre00020 apre01200 apre01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:apre00020 apre01200 apre01210 apre01230 apre01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:apre00020 apre01200 apre01210 apre01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:apre00030 apre01200 apre01100 apre01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:apre00030 apre01200 apre01100 apre01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:apre00030 apre01200 apre01230 apre01100 apre01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:apre00030 apre00230 apre01200 apre01230 apre01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:apre00030 apre01200 apre01100 apre01120]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:apre00052 apre01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:apre00500 apre01100]
M00012 Glyoxylate cycle [PATH:apre00630 apre01200 apre01100 apre01110]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:apre00280 apre00630 apre00640 apre01200 apre01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:apre00910 apre01310 apre01100 apre01120]

Sulfur metabolism
Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:apre00190 apre01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:apre00190 apre01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:apre00190 apre01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:apre00190 apre01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:apre00190 apre01100]

Lipid metabolism
Fatty acid metabolism
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:apre00061 apre00071 apre01212 apre01100]
M00087 beta-Oxidation [PATH:apre00071 apre01212 apre01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:apre00564 apre01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:apre00230 apre01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:apre00230 apre01232 apre01240 apre01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:apre00230 apre01232 apre01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:apre00230 apre00240 apre01232 apre01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:apre00240 apre01232 apre01240 apre01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:apre00240 apre01232 apre01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:apre00260 apre00680 apre01200 apre01230 apre01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:apre00260 apre01230 apre01100 apre01110]
M00621 Glycine cleavage system [PATH:apre00260 apre00630 apre00670 apre00785 apre01200 apre01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:apre00260 apre00270 apre00670 apre01230 apre01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:apre00270 apre01230 apre01100]
M00035 Methionine degradation [PATH:apre00270 apre00670 apre01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:apre00290 apre00770 apre01210 apre01230 apre01100 apre01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:apre00290 apre01230 apre01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:apre00290 apre01210 apre01230 apre01100 apre01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:apre00280 apre01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:apre00300 apre01230 apre01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:apre00220 apre01210 apre01230 apre01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:apre00220 apre01230 apre01100]
M00978 Ornithine-ammonia cycle [PATH:apre00220 apre01100 apre01110]
M00015 Proline biosynthesis, glutamate => proline [PATH:apre00330 apre01230 apre01100]
M00970 Proline degradation, proline => glutamate [PATH:apre00330 apre01100]
M00972 Proline metabolism [PATH:apre00330 apre01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:apre00330 apre01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:apre00340 apre01230 apre01100 apre01110]

Aromatic amino acid metabolism
Other amino acid metabolism
M00949 Staphylopine biosynthesis, L-histidine => staphylopine [PATH:apre00470 apre01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:apre00520 apre01250 apre01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:apre00520]
M01004 UDP-Galf biosynthesis, UDP-Glc => UDP-Galf [PATH:apre00520 apre00052]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:apre00520 apre00052 apre01250 apre01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:apre00520]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:apre00521 apre00523 apre00541 apre01250 apre01100 apre01110]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:apre00750 apre01240 apre01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:apre00760 apre01240 apre01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:apre00770 apre01240 apre01100 apre01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:apre00770 apre01240 apre01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:apre00780 apre01240 apre01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:apre00785 apre01240 apre01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:apre00860 apre01240 apre01100 apre01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:apre00860 apre01240 apre01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:apre00860 apre01240 apre01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:apre00900 apre01100 apre01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:apre00900 apre01100 apre01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity